miRTarBase - #MIRT438602


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pre-miRNA Information
pre-miRNA hsa-mir-758   
Genomic Coordinates chr14: 101026020 - 101026107
Synonyms MIRN758, hsa-mir-758, MIR758
Description Homo sapiens miR-758 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-758-3p
Sequence 52| UUUGUGACCUGGUCCACUAACC |73
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs992122694 10 dbSNP
rs1165305945 14 dbSNP
rs1432780238 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TLR7   
Synonyms TLR7-like
Description toll like receptor 7
Transcript NM_016562   
Expression
Putative miRNA Targets on TLR7
3'UTR of TLR7
(miRNA target sites are highlighted)		 
>TLR7|NM_016562|3'UTR
   1 CCCTTCTTTGCAAAACACAACTGCCTAGTTTACCAAGGAGAGGCCTGGCTGTTTAAATTGTTTTCATATATATCACACCA
  81 AAAGCGTGTTTTGAAATTCTTCAAGAAATGAGATTGCCCATATTTCAGGGGAGCCACCAACGTCTGTCACAGGAGTTGGA
 161 AAGATGGGGTTTATATAATGCATCAAGTCTTCTTTCTTATCTCTCTGTGTCTCTATTTGCACTTGAGTCTCTCACCTCAG
 241 CTCCTGTAAAAGAGTGGCAAGTAAAAAACATGGGGCTCTGATTCTCCTGTAATTGTGATAATTAAATATACACACAATCA
 321 TGACATTGAGAAGAACTGCATTTCTACCCTTAAAAAGTACTGGTATATACAGAAATAGGGTTAAAAAAAACTCAAGCTCT
 401 CTCTATATGAGACCAAAATGTACTAGAGTTAGTTTAGTGAAATAAAAAACCAGTCAGCTGGCCGGGCATGGTGGCTCATG
 481 CTTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTTTGAGACCAGTCTGGCCAACATGGT
 561 GAAACCCCGTCTGTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCT
 641 GAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGGTGGCAGTGAGCCGAGATCACGCCACTGCAATGCAGCCCGGGCAA
 721 CAGAGCTAGACTGTCTCAAAAGAACAAAAAAAAAAAAACACAAAAAAACTCAGTCAGCTTCTTAACCAATTGCTTCCGTG
 801 TCATCCAGGGCCCCATTCTGTGCAGATTGAGTGTGGGCACCACACAGGTGGTTGCTGCTTCAGTGCTTCCTGCTCTTTTT
 881 CCTTGGGCCTGCTTCTGGGTTCCATAGGGAAACAGTAAGAAAGAAAGACACATCCTTACCATAAATGCATATGGTCCACC
 961 TACAAATAGAAAAATATTTAAATGATCTGCCTTTATACAAAGTGATATTCTCTACCTTTGATAATTTACCTGCTTAAATG
1041 TTTTTATCTGCACTGCAAAGTACTGTATCCAAAGTAAAATTTCCTCATCCAATATCTTTCAAACTGTTTTGTTAACTAAT
1121 GCCATATATTTGTAAGTATCTGCACACTTGATACAGCAACGTTAGATGGTTTTGATGGTAAACCCTAAAGGAGGACTCCA
1201 AGAGTGTGTATTTATTTATAGTTTTATCAGAGATGACAATTATTTGAATGCCAATTATATGGATTCCTTTCATTTTTTGC
1281 TGGAGGATGGGAGAAGAAACCAAAGTTTATAGACCTTCACATTGAGAAAGCTTCAGTTTTGAACTTCAGCTATCAGATTC
1361 AAAAACAACAGAAAGAACCAAGACATTCTTAAGATGCCTGTACTTTCAGCTGGGTATAAATTCATGAGTTCAAAGATTGA
1441 AACCTGACCAATTTGCTTTATTTCATGGAAGAAGTGATCTACAAAGGTGTTTGTGCCATTTGGAAAACAGCGTGCATGTG
1521 TTCAAGCCTTAGATTGGCGATGTCGTATTTTCCTCACGTGTGGCAATGCCAAAGGCTTTACTTTACCTGTGAGTACACAC
1601 TATATGAATTATTTCCAACGTACATTTAATCAATAAGGGTCACAAATTCCCAAATCAATCTCTGGAATAAATAGAGAGGT
1681 AATTAAATTGCTGGAGCCAACTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccAAUCACCUGGU-CCAGUGUUu 5'
            ||| |  |: | |||||||| 
Target 5' atTTAATCAATAAGGGTCACAAa 3'
 1624 - 1646 156.00 -13.00
2 
miRNA  3' ccAAUCACC----UGGU--C---CAGUGUUu 5'
            | || ||    ||||  |   ||||||: 
Target 5' ttTCAGGGGAGCCACCAACGTCTGTCACAGg 3'
 123 - 153 132.00 -13.10
3 
miRNA  3' ccaaUCACCUGG---UCCAGUGUUu 5'
              :|||||:|   |||||| :| 
Target 5' ggcaGGTGGATCACGAGGTCAGGAg 3'
 510 - 534 122.00 -20.30
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1484294227 2 dbSNP
rs149611837 3 dbSNP
rs867332804 22 dbSNP
rs199920583 24 dbSNP
rs751496742 34 dbSNP
rs756192232 43 dbSNP
rs1183290880 50 dbSNP
rs769564508 61 dbSNP
rs1441014646 65 dbSNP
rs1241487046 66 dbSNP
rs978183669 66 dbSNP
rs773337198 70 dbSNP
rs1056679474 73 dbSNP
rs1353540372 79 dbSNP
rs201277735 86 dbSNP
rs56082712 87 dbSNP
rs939094310 90 dbSNP
rs200011546 91 dbSNP
rs1445446781 103 dbSNP
rs948229635 118 dbSNP
rs201146128 128 dbSNP
rs1247538669 130 dbSNP
rs201968045 132 dbSNP
rs916084034 133 dbSNP
rs948904253 137 dbSNP
rs1425608047 138 dbSNP
rs1479027899 139 dbSNP
rs1037948049 142 dbSNP
rs934982989 143 dbSNP
rs200445195 151 dbSNP
rs901549660 154 dbSNP
rs1265623117 159 dbSNP
rs1217760385 167 dbSNP
rs751676202 175 dbSNP
rs201428022 180 dbSNP
rs202076217 187 dbSNP
rs1048207601 190 dbSNP
rs1224486747 190 dbSNP
rs200340601 201 dbSNP
rs1171119914 212 dbSNP
rs10127190 219 dbSNP
rs1226132825 228 dbSNP
rs1341918514 236 dbSNP
rs201310571 238 dbSNP
rs199761230 240 dbSNP
rs200773978 244 dbSNP
rs755539535 248 dbSNP
rs143313366 251 dbSNP
rs1437914908 258 dbSNP
rs1350524489 259 dbSNP
rs759605129 272 dbSNP
rs1164098808 287 dbSNP
rs199575918 297 dbSNP
rs200693848 299 dbSNP
rs753405332 300 dbSNP
rs754714991 310 dbSNP
rs201567667 312 dbSNP
rs200016156 313 dbSNP
rs972866866 314 dbSNP
rs964508102 318 dbSNP
rs1261567384 322 dbSNP
rs200783165 329 dbSNP
rs1489060292 331 dbSNP
rs1026061217 364 dbSNP
rs1218688323 369 dbSNP
rs1022193520 371 dbSNP
rs1333091687 373 dbSNP
rs1258279280 380 dbSNP
rs1338137476 383 dbSNP
rs967046441 383 dbSNP
rs1303209095 386 dbSNP
rs369975829 391 dbSNP
rs201629586 394 dbSNP
rs200181830 406 dbSNP
rs977754711 407 dbSNP
rs201136928 410 dbSNP
rs189026559 412 dbSNP
rs1453557210 415 dbSNP
rs202049781 421 dbSNP
rs1291740935 422 dbSNP
rs182036901 423 dbSNP
rs1434374607 424 dbSNP
rs1213719405 427 dbSNP
rs1241668100 428 dbSNP
rs1465355725 431 dbSNP
rs927625228 437 dbSNP
rs199903697 450 dbSNP
rs201214925 455 dbSNP
rs1267214058 459 dbSNP
rs5743782 464 dbSNP
rs1194364943 465 dbSNP
rs202137473 470 dbSNP
rs1238327966 476 dbSNP
rs990565734 481 dbSNP
rs1425728465 482 dbSNP
rs948198744 484 dbSNP
rs200428157 495 dbSNP
rs201172799 503 dbSNP
rs1162445332 508 dbSNP
rs980021532 508 dbSNP
rs201946332 509 dbSNP
rs1414049888 511 dbSNP
rs758275345 518 dbSNP
rs925503492 522 dbSNP
rs200605695 525 dbSNP
rs1332057656 538 dbSNP
rs1446138626 543 dbSNP
rs201185476 547 dbSNP
rs1038294937 552 dbSNP
rs199703164 553 dbSNP
rs920828141 554 dbSNP
rs189271787 569 dbSNP
rs929556047 570 dbSNP
rs1442144101 573 dbSNP
rs200230134 574 dbSNP
rs1047685039 594 dbSNP
rs1400108556 601 dbSNP
rs201028576 602 dbSNP
rs199802050 607 dbSNP
rs1200717696 608 dbSNP
rs1354122360 612 dbSNP
rs1254091217 613 dbSNP
rs200778441 619 dbSNP
rs5743783 629 dbSNP
rs1354246758 633 dbSNP
rs1308487580 634 dbSNP
rs1285218056 638 dbSNP
rs570004415 639 dbSNP
rs199536456 655 dbSNP
rs201000960 656 dbSNP
rs1283623810 665 dbSNP
rs201834069 666 dbSNP
rs897695550 676 dbSNP
rs199971769 679 dbSNP
rs749509695 680 dbSNP
rs1265171613 684 dbSNP
rs900620161 685 dbSNP
rs1369765160 689 dbSNP
rs1484683115 694 dbSNP
rs1187803795 695 dbSNP
rs994650274 697 dbSNP
rs768926097 698 dbSNP
rs200940642 715 dbSNP
rs1025733679 716 dbSNP
rs1237880480 738 dbSNP
rs1009306826 743 dbSNP
rs1245622262 746 dbSNP
rs1356697588 746 dbSNP
rs201617174 746 dbSNP
rs371951034 746 dbSNP
rs535557686 746 dbSNP
rs1010714448 748 dbSNP
rs200167328 749 dbSNP
rs1022560480 757 dbSNP
rs375210636 758 dbSNP
rs80280330 758 dbSNP
rs1399531599 759 dbSNP
rs74924954 760 dbSNP
rs1163266448 762 dbSNP
rs1393538522 762 dbSNP
rs773541794 769 dbSNP
rs200309779 776 dbSNP
rs201020241 779 dbSNP
rs1159948589 784 dbSNP
rs201873998 791 dbSNP
rs1195464278 800 dbSNP
rs200284325 801 dbSNP
rs1262288207 810 dbSNP
rs1191402471 811 dbSNP
rs1034974779 819 dbSNP
rs201121825 820 dbSNP
rs186383115 827 dbSNP
rs189922210 828 dbSNP
rs1355754978 846 dbSNP
rs200594450 847 dbSNP
rs990513295 848 dbSNP
rs1440495816 851 dbSNP
rs1277902161 860 dbSNP
rs1308714363 863 dbSNP
rs1429073642 876 dbSNP
rs5743784 880 dbSNP
rs3853839 882 dbSNP
rs1391703136 888 dbSNP
rs200584616 903 dbSNP
rs5743785 906 dbSNP
rs1342744031 914 dbSNP
rs935521964 914 dbSNP
rs1023367179 916 dbSNP
rs199793344 930 dbSNP
rs72552315 931 dbSNP
rs1279269498 932 dbSNP
rs72552316 934 dbSNP
rs201731284 936 dbSNP
rs199850221 947 dbSNP
rs962466999 953 dbSNP
rs932946081 957 dbSNP
rs201382146 958 dbSNP
rs201825820 968 dbSNP
rs182519380 979 dbSNP
rs973562842 984 dbSNP
rs1318797147 989 dbSNP
rs1257701630 992 dbSNP
rs1213127751 999 dbSNP
rs746889496 1008 dbSNP
rs746577358 1012 dbSNP
rs1439988432 1031 dbSNP
rs1275930684 1034 dbSNP
rs1233241278 1056 dbSNP
rs200825767 1060 dbSNP
rs1037656098 1066 dbSNP
rs12861036 1069 dbSNP
rs200136600 1076 dbSNP
rs200944677 1085 dbSNP
rs929532698 1090 dbSNP
rs202202029 1091 dbSNP
rs200299179 1093 dbSNP
rs1392768945 1101 dbSNP
rs201397543 1101 dbSNP
rs202110441 1102 dbSNP
rs1415936135 1106 dbSNP
rs781281045 1125 dbSNP
rs200353251 1126 dbSNP
rs201328919 1127 dbSNP
rs199556821 1129 dbSNP
rs186028172 1133 dbSNP
rs912176412 1146 dbSNP
rs1180549435 1147 dbSNP
rs190407990 1148 dbSNP
rs1013651435 1150 dbSNP
rs199637856 1155 dbSNP
rs1408515963 1161 dbSNP
rs200662302 1162 dbSNP
rs201804848 1177 dbSNP
rs969399656 1184 dbSNP
rs1200250387 1187 dbSNP
rs1346254949 1189 dbSNP
rs1001491067 1193 dbSNP
rs1240179253 1198 dbSNP
rs1032598819 1199 dbSNP
rs200143078 1203 dbSNP
rs766423908 1209 dbSNP
rs1277375259 1212 dbSNP
rs1449854258 1215 dbSNP
rs5743786 1220 dbSNP
rs1333185706 1229 dbSNP
rs957070067 1236 dbSNP
rs900564466 1244 dbSNP
rs988342313 1247 dbSNP
rs188916453 1259 dbSNP
rs923464625 1267 dbSNP
rs954429195 1275 dbSNP
rs1407438433 1281 dbSNP
rs1234091015 1284 dbSNP
rs774514648 1299 dbSNP
rs1238270784 1309 dbSNP
rs769499471 1316 dbSNP
rs1347060488 1317 dbSNP
rs199936370 1322 dbSNP
rs910210155 1323 dbSNP
rs1288755110 1331 dbSNP
rs201018444 1342 dbSNP
rs34579000 1342 dbSNP
rs192357402 1345 dbSNP
rs1217214825 1354 dbSNP
rs919197358 1357 dbSNP
rs896426314 1359 dbSNP
rs1229543515 1361 dbSNP
rs1200198207 1379 dbSNP
rs1379393337 1381 dbSNP
rs200045264 1386 dbSNP
rs370353258 1396 dbSNP
rs1432052492 1399 dbSNP
rs1023314850 1401 dbSNP
rs201056208 1425 dbSNP
rs202115250 1438 dbSNP
rs749004761 1444 dbSNP
rs200448180 1445 dbSNP
rs962452740 1462 dbSNP
rs1343375281 1464 dbSNP
rs974227443 1482 dbSNP
rs1407182225 1489 dbSNP
rs201433363 1497 dbSNP
rs182605992 1513 dbSNP
rs202079175 1519 dbSNP
rs895676175 1533 dbSNP
rs1013620412 1534 dbSNP
rs200233209 1539 dbSNP
rs761079754 1540 dbSNP
rs1265877040 1542 dbSNP
rs1194865705 1543 dbSNP
rs1485790083 1546 dbSNP
rs1240898182 1553 dbSNP
rs201409174 1558 dbSNP
rs766965935 1559 dbSNP
rs150774542 1561 dbSNP
rs759081118 1565 dbSNP
rs1032978365 1575 dbSNP
rs139169733 1576 dbSNP
rs200891793 1580 dbSNP
rs1030504574 1594 dbSNP
rs1390300096 1599 dbSNP
rs1399165683 1603 dbSNP
rs1359725299 1612 dbSNP
rs1295239360 1615 dbSNP
rs201405977 1620 dbSNP
rs199579708 1621 dbSNP
rs1387371208 1631 dbSNP
rs1460124266 1632 dbSNP
rs1426058419 1633 dbSNP
rs1171786181 1634 dbSNP
rs752380482 1664 dbSNP
rs1325682847 1673 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions QSG-7701
Disease MIMAT0003879
Location of target site 3'UTR
Tools used in this research miRanda , Pictar
Original Description (Extracted from the article) ... "we transfected QSG-7701 cells with miR-758 mimics and inhibitors. The results showed that miR-758 down-regulated both TLR3 and TLR7 expression and that its inhibitor could upregulate both TLR3 and TLR7 expression (Fig. 4B). Furthermore ...

- Yang Q; Fu S; Wang J, 2014, Archives of virology.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ccAAUCACCUGGU-CCAGUGUUu 5'
            ||| |  |: | |||||||| 
Target 5' auUUAAUCAAUAAGGGUCACAAa 3'
 		1 - 23
Article - Yang Q; Fu S; Wang J
- Archives of virology, 2014
Chronic infection with hepatotropic viruses is the main cause of chronic liver disease and cirrhosis worldwide. Toll-like receptor 3 (TLR3) and Toll-like receptor 7 (TLR7) are pathogen-recognition receptors that are expressed on innate immune cells. They recognize viral RNA, which induces their activation, with a subsequent increase in type I interferon transcription. Hepatitis C virus (HCV) infection inhibits the expression of TLR3 and TLR7; however, the mechanism by which this occurs is unclear. MicroRNAs (miRNAs) are small RNAs that posttranscriptionally regulate gene expression. Their aberrant expression is commonly correlated with disease status, as is the case with HCV infection. Here, we found that miR-758 levels were increased in patients with HCV infection and were correlated with TLR3 and TLR7 expression levels in the patients with HCV infection, and bioinformatics analysis predicted that TLR3 and TLR7 are targets of miR-758. Therefore, we postulate that HCV may increase the level of miR-758, which inhibits the expression of TLR3 and TLR7, resulting in a loss of antiviral effect. In order to test our hypothesis, we constructed an HCV core protein expression plasmid and used it to transfect liver cells. The results showed that HCV infection increased miR-758 levels and decreased TLR3/TLR7 expression. Furthermore, using RT-PCR and luciferase reporter analysis, we found that miR-758 targets TLR3 and TLR7, with a subsequent decrease in IFNalpha and IFNbeta production. In conclusion, our results highlight the upregulation of miR-758 expression by HCV as a novel mechanism contributing to downregulation of TLR3 and TLR7 in patients with HCV infection.
LinkOut: [PMID: 25008898]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE21849 B cell lymphoma -0.366 2.5e-2 -0.348 3.2e-2 29 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.321 5.9e-2 -0.236 1.3e-1 25 Click to see details
GSE28544 Breast cancer 0.277 9.5e-2 0.242 1.3e-1 24 Click to see details
GSE32688 Pancreatic cancer -0.235 9.8e-2 -0.057 3.8e-1 32 Click to see details
GSE21687 Ependynoma primary tumors -0.161 1.0e-1 -0.049 3.5e-1 64 Click to see details
GSE17498 Multiple myeloma 0.202 1.1e-1 0.080 3.1e-1 40 Click to see details
GSE19783 ER- ER- breast cancer 0.133 1.2e-1 0.135 1.2e-1 79 Click to see details
GSE27834 Pluripotent stem cells 0.268 1.6e-1 0.682 1.8e-3 16 Click to see details
GSE19350 CNS germ cell tumors -0.287 1.8e-1 -0.469 6.2e-2 12 Click to see details
GSE28260 Renal cortex and medulla -0.269 1.9e-1 -0.258 2.0e-1 13 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.162 2.5e-1 0.244 1.5e-1 20 Click to see details
GSE19536 Breast cancer 0.052 3.0e-1 0.033 3.7e-1 100 Click to see details
GSE17306 Multiple myeloma -0.071 3.1e-1 0.177 1.1e-1 49 Click to see details
GSE19783 ER+ ER+ breast cancer -0.115 3.1e-1 -0.026 4.6e-1 20 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.026 4.5e-1 -0.097 3.2e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.026 4.5e-1 -0.097 3.2e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRC 0.317 0.01 0.279 0.02 52 Click to see details
KICH 0.451 0.02 0.454 0.01 23 Click to see details
KIRP 0.351 0.03 0.432 0.01 29 Click to see details
CESC 0.995 0.03 0.500 0.33 3 Click to see details
PRAD -0.196 0.09 -0.152 0.15 50 Click to see details
STAD 0.212 0.12 0.150 0.21 32 Click to see details
HNSC 0.183 0.12 0.257 0.05 42 Click to see details
LIHC 0.151 0.15 0.158 0.14 49 Click to see details
LUSC -0.164 0.16 -0.102 0.27 38 Click to see details
PCPG 0.781 0.21 0.500 0.33 3 Click to see details
CHOL 0.289 0.23 0.333 0.19 9 Click to see details
LUAD 0.169 0.3 0.203 0.26 12 Click to see details
ESCA 0.167 0.31 0.200 0.28 11 Click to see details
BRCA 0.05 0.33 0.049 0.33 84 Click to see details
BLCA 0.104 0.34 0.065 0.4 18 Click to see details
UCEC 0.04 0.44 0.063 0.4 19 Click to see details
PAAD -0.095 0.45 -0.400 0.3 4 Click to see details
COAD -0.045 0.46 0.190 0.33 8 Click to see details
THCA -0.011 0.47 -0.069 0.32 50 Click to see details
THCA -0.011 0.47 -0.069 0.32 50 Click to see details
THCA -0.011 0.47 -0.069 0.32 50 Click to see details
48 hsa-miR-758-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT118609 NCOA3 nuclear receptor coactivator 3 2 2
MIRT122451 SMIM13 small integral membrane protein 13 2 2
MIRT438602 TLR7 toll like receptor 7 3 1
MIRT438603 TLR3 toll like receptor 3 3 1
MIRT446951 CD248 CD248 molecule 2 2
MIRT447942 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT450648 TMEM70 transmembrane protein 70 2 2
MIRT463976 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT465151 TSC22D2 TSC22 domain family member 2 2 2
MIRT468670 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT469019 RNF41 ring finger protein 41 2 2
MIRT475623 HMGA1 high mobility group AT-hook 1 2 4
MIRT485794 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT492982 NAV1 neuron navigator 1 2 2
MIRT493720 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT498889 RBM12B RNA binding motif protein 12B 2 4
MIRT499194 TJAP1 tight junction associated protein 1 2 2
MIRT499331 RAB25 RAB25, member RAS oncogene family 2 2
MIRT510550 WTAP WT1 associated protein 2 4
MIRT524405 COL4A1 collagen type IV alpha 1 chain 2 4
MIRT530160 C11orf44 chromosome 11 open reading frame 44 2 2
MIRT534595 RORA RAR related orphan receptor A 2 2
MIRT538452 CNKSR2 connector enhancer of kinase suppressor of Ras 2 2 2
MIRT543494 MDM2 MDM2 proto-oncogene 2 4
MIRT547860 HSPA13 heat shock protein family A (Hsp70) member 13 2 2
MIRT553785 TACC1 transforming acidic coiled-coil containing protein 1 2 2
MIRT553903 SUN2 Sad1 and UNC84 domain containing 2 2 4
MIRT559303 ATXN1 ataxin 1 2 2
MIRT563350 ZNF181 zinc finger protein 181 2 2
MIRT565404 TFDP1 transcription factor Dp-1 2 2
MIRT566891 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT613227 CCDC39 coiled-coil domain containing 39 2 2
MIRT613470 TG thyroglobulin 2 4
MIRT619930 WSCD2 WSC domain containing 2 2 2
MIRT627180 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT632962 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT634304 SNTN sentan, cilia apical structure protein 2 2
MIRT635292 IRX2 iroquois homeobox 2 2 2
MIRT639740 SLC1A1 solute carrier family 1 member 1 2 2
MIRT641892 SMNDC1 survival motor neuron domain containing 1 2 2
MIRT645871 PRRG3 proline rich and Gla domain 3 2 2
MIRT648691 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT650048 KRBA1 KRAB-A domain containing 1 2 2
MIRT667626 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT669725 A1CF APOBEC1 complementation factor 2 2
MIRT710429 BTNL3 butyrophilin like 3 2 2
MIRT710805 SLC4A1AP solute carrier family 4 member 1 adaptor protein 2 2
MIRT723980 SOX17 SRY-box 17 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-758 Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-758 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-758 5-Fluorouracil approved 3385 Quantitative real-time PCR human squamous cell carcinoma cell line KYSE410 21743970 2011 up-regulated
miR-758 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-758 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-758 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-mir-758 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-758-3p (1-(((2-amino-6-chloro-4-pyrimidinyl)amino)methyl)-3-isopropylcyclobutyl)methanol 385230 NSC676343 sensitive
hsa-miR-758-3p (2e)-2-hydroxyimino-4-(3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-yl)-4-oxo-n-(2,4,5-trichlorophenyl)butanamide 6399319 NSC635544 resistant
hsa-miR-758-3p (2E,5Z)-2-[(5-acetyl-4-methyl-1,3-thiazol-2-yl)hydrazinylidene]-5-[(2-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one 135472679 NSC658292 sensitive
hsa-miR-758-3p (2S,6S,7S,12R)-16-bromo-9-tert-butyl-4-phenyl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 372657 NSC648154 sensitive
hsa-miR-758-3p (3-(trifluoromethyl)anilino)(2-(trifluoromethyl)phenyl)acetonitrile 375079 NSC654017 resistant
hsa-miR-758-3p (3e)-3-[(2-chloro-1-phenylindol-3-yl)methylidene]-5-methoxy-1h-indol-2-one 5471470 NSC711610 sensitive
hsa-miR-758-3p (4E)-2-(2-hydroxybenzoyl)-5-methyl-4-[(4-nitrophenyl)methylidene]pyrazol-3-one 5467414 NSC652175 sensitive
hsa-miR-758-3p (E)-1-[4-(quinazolin-4-ylamino)phenyl]-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one 155816064 NSC760015 sensitive
hsa-miR-758-3p (E)-3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)-methylamino]-2-oxoethyl]prop-2-enamide 51003603 NSC761184 resistant
hsa-miR-758-3p (NE)-N-[(6E)-2-[(hydroxyamino)-(4-phenylmethoxyphenyl)methyl]-6-[(4-phenylmethoxyphenyl)methylidene]cyclohexylidene]hydroxylamine 5928828 NSC632824 resistant
hsa-miR-758-3p [(11bR)-9,10-dimethoxy-4-phenylimino-2,6,7,11b-tetrahydro-1H-[1,3]thiazino[4,3-a]isoquinolin-1-yl]methyl benzoate 371073 NSC645016 sensitive
hsa-miR-758-3p [(1s,2s,3r,4s,7r,9s,10s,12r,15s)-4,12-diacetyloxy-15-[(2r,3s)-3-benzamido-2-hydroxy-3-(2-methylphenyl)propanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]hepta 383478 NSC671870 sensitive
hsa-miR-758-3p [(4e)-4-[2-(3,3,6a,10b-tetramethyl-8-methylidene-1,4a,5,6,7,9,10,10a-octahydronaphtho[2,1-d][1,3]dioxin-7-yl)ethylidene]-5-oxooxolan-3-yl] acetate 25121273 NSC750035 resistant
hsa-miR-758-3p [1-[[[2-amino-6-chloro-5-[(4-chlorophenyl)diazenyl]pyrimidin-4-yl]amino]methyl]-3-phenylmethoxycyclobutyl]methanol 385284 NSC676395 resistant
hsa-miR-758-3p [5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl [5-[5-fluoro-4-(octadecylamino)-2-oxopyrimidin-1-yl]-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate 390213 NSC687370 sensitive
hsa-miR-758-3p [acetyl-[5-(trityloxymethyl)spiro[3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole-2,1'-cyclopentane]-6-yl]amino] acetate 374290 NSC651809 sensitive
hsa-miR-758-3p {2-[(benzylamino)methyl]-1h-indole-1,3-diyl}bis(phenylmethanone) 374841 NSC653267 sensitive
hsa-miR-758-3p 1-(2-methoxyphenyl)-3-[(z)-1-(2-pyridyl)ethylideneamino]thiourea 5367237 NSC668297 resistant
hsa-miR-758-3p 1-(9-methoxy-11,12-dihydro-6h-indolo[1,2-b][2]benzazepin-13-yl)ethanone 365697 NSC633551 sensitive
hsa-miR-758-3p 1-[(4-bromophenyl)amino]cyclopentanecarbonitrile 238637 NSC43101 resistant
hsa-miR-758-3p 1-[5-[[[4-chlorobutyl(methyl)amino]-[(5-nitrofuran-2-yl)methoxy]phosphoryl]oxymethyl]-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione 404846 NSC721390 sensitive
hsa-miR-758-3p 1-benzyl-2-methyl-1-(2-phenylethyl)-4,5-dihydroimidazol-1-ium 413544 NSC49460 sensitive
hsa-miR-758-3p 16-methoxy-4-(4-methoxyphenyl)-9-propan-2-yl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 390916 NSC689137 sensitive
hsa-miR-758-3p 17-acetyl-9,14-dihydroxy-16-methyl-15-(4-methylphenyl)-15-azatetracyclo[8.7.0.01,14.03,8]heptadeca-3,5,7,9,12,16-hexaene-2,11-dione 405612 NSC722982 resistant
hsa-miR-758-3p 2'-(4-chlorobenzoyl)-1'-(4-chlorophenyl)-1'-hydroxyspiro[1,3-dihydro-1-benzazepine-4,4'-cyclohexane]-2,5-dione 388188 NSC682756 sensitive
hsa-miR-758-3p 2-(4-chlorophenyl)-1-methylene-3-phenyl-pyrazino[1,2-a]benzimidazole 390230 NSC687522 resistant
hsa-miR-758-3p 2-(hydroxymethyl)-5-[6-(2-propan-2-ylidenehydrazinyl)purin-9-yl]oxolane-3,4-diol 60147745 NSC752330 resistant
hsa-miR-758-3p 2-(trifluoromethyl)benzimidazo[2,1-b][1,3,5]benzothiadiazepin-12(13h)-imine 383194 NSC671313 sensitive
hsa-miR-758-3p 2-[2-[5-(ethoxycarbonylcarbamoyl)-3-methyl-2,4-dioxopyrimidin-1-yl]ethylsulfanyl]ethyl n-[6-[2-[2-[5-(ethoxycarbonylcarbamoyl)-3-methyl-2,4-dioxopyrimidin-1-yl]ethylsulfanyl]ethoxycarbonylamino]hexyl] 367630 NSC637505 sensitive
hsa-miR-758-3p 2-[2-methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]acetic acid 5934333 NSC643813 sensitive
hsa-miR-758-3p 2-[9-[(7-oxocyclohepta-1,3,5-trien-1-yl)amino]nonylamino]cyclohepta-2,4,6-trien-1-one 358331 NSC618296 sensitive
hsa-miR-758-3p 2-acetyl-1,2-dihydroellipticine 376328 NSC657149 resistant
hsa-miR-758-3p 2-azaadenine 5480214 NSC57048 resistant
hsa-miR-758-3p 2-methyl-1-[10-[(2-methylquinolin-4-yl)amino]decyl]quinolin-1-ium-4-amine;chloride;hydrochloride 387885 NSC682096 sensitive
hsa-miR-758-3p 2-methyl-4,4-diphenyl-1,4-benzoxaphosphinin-4-ium;bromide 24199840 NSC346098 sensitive
hsa-miR-758-3p 2-methylellpticinium 21123185 NSC351710 sensitive
hsa-miR-758-3p 2-methylolivacinium acetate 5458752 NSC336003 sensitive
hsa-miR-758-3p 2-n-methyl-6-thiaellipticinum iodide 367888 NSC638066 sensitive
hsa-miR-758-3p 2,2'-spirobi[indane]-5,5'-dicarbaldehyde 382743 NSC670421 sensitive
hsa-miR-758-3p 2,3-dibenzoyloxy-4-hydroxy-4-oxobutanoate;(2,5-dimethylphenyl)-(4-methylphenyl)-phenylsulfanium 5351228 NSC116693 sensitive
hsa-miR-758-3p 2,5-dibenzyl-2-undecyloctahydro-1h-pyrrolo[3,4-c]pyridin-2-ium bromide 378731 NSC661832 sensitive
hsa-miR-758-3p 2,5,11-trimethyl-9-phenoxy-6h-pyrido[4,3-b]carbazol-2-ium;acetate 10431819 NSC650269 sensitive
hsa-miR-758-3p 2,5,12-trimethyl-[1,4]benzodioxino[3,2-g]isoquinolin-2-ium acetate 388316 NSC683048 sensitive
hsa-miR-758-3p 3-(4-methoxyphenyl)-4-methyl-8-pyrrolidin-1-yl-8H-thieno[2,3-b]pyrrolizin-4-ium;iodide 388538 NSC683518 sensitive
hsa-miR-758-3p 3-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)-1,4-dioxane-2,6-diol 269951 NSC111702 resistant
hsa-miR-758-3p 3-bromo-4-(3,3-dimethyl-but-1-ynyl)-2(5h)-furanone 11413833 NSC726328 resistant
hsa-miR-758-3p 3,3-bis(3-(trifluoromethyl)phenyl)naphtho[1,2-c]furan-1(3h)-one 362080 NSC625603 sensitive
hsa-miR-758-3p 4-(4-carbazol-9-ylbutanoylamino)-n-[5-[3-(dimethylamino)propylcarbamoyl]-1-methylpyrrol-3-yl]-1-methylpyrrole-2-carboxamide 406397 NSC724462 sensitive
hsa-miR-758-3p 4-(bromomethyl)-2,2,5,5-tetramethyl-1-imidazolidinol 3-oxide 378673 NSC661470 resistant
hsa-miR-758-3p 4-[(13R)-13-hydroxy-13-[(2S,5S)-5-[(2S,5S)-5-[1-hydroxy-13-[(2S)-2-methyl-5-oxo-2H-furan-4-yl]tridecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]-2-methyl-2H-furan-5-one 374064 NSC651320 sensitive
hsa-miR-758-3p 4-[[(Z)-N-benzamido-C-[4-[bis(2-cyanoethyl)amino]-2-methylphenyl]carbonimidoyl]diazenyl]benzoic acid 135493923 NSC681974 sensitive
hsa-miR-758-3p 4-[4-(diethylamino)phenyl]-2-(4-hydroxypiperidin-1-yl)-6-(3,4,5-trimethoxyphenyl)pyridine-3-carbonitrile 60148088 NSC753601 resistant
hsa-miR-758-3p 4-[4-[2,3-bis(hydroxymethyl)pyrrol-1-yl]butanoylamino]-n-[5-[[5-[3-(dimethylamino)propylcarbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-1-methylpyrrole-2-carboxamide 384021 NSC673131 sensitive
hsa-miR-758-3p 4-methoxy-1,5-benzothiazepine-1,1-dioxide 358940 NSC619102 resistant
hsa-miR-758-3p 4-methyl-1,1-diphenyl-1,2,3,4-tetrahydrobenzo(h)phosphinolinium hexafluorophosphate 498151 NSC245398 sensitive
hsa-miR-758-3p 4-naphthalen-2-yl-2,4-dioxo-3-(3-oxo-1H-2-benzofuran-1-yl)-N-[3-(trifluoromethyl)phenyl]butanamide 369471 NSC641241 sensitive
hsa-miR-758-3p 4-pyridin-3-yl-2-(2,3,5-trichlorophenyl)-1,3-thiazole 24814783 NSC742842 resistant
hsa-miR-758-3p 4,10-bis(3-ethynylphenyl)-4,10-diazatetracyclo[5.5.2.02,6.08,12]tetradec-13-ene-3,5,9,11-tetrone 365547 NSC633253 sensitive
hsa-miR-758-3p 5-benzyl-5h-benzo[b]phosphindole 5-oxide 380786 NSC666496 sensitive
hsa-miR-758-3p 5-hydroxy-3,7-dimethoxy-3',4'-methylenedioxyflavone 5466137 NSC678102 sensitive
hsa-miR-758-3p 5-methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 NSC748147 sensitive
hsa-miR-758-3p 5,11-dimethyl-2-[(pentanoyloxy)methyl]-6h-pyrido[4,3-b]carbazol-2-ium iodide 367409 NSC637130 sensitive
hsa-miR-758-3p 6-aminotoyocamycin 300567 NSC175630 resistant
hsa-miR-758-3p 6-bromosangivamycin 270853 NSC113943 resistant
hsa-miR-758-3p 6,7-dimethyl-4-[(2z)-2-(5-oxooxolan-2-ylidene)ethoxy]chromen-2-one 24205380 NSC735332 resistant
hsa-miR-758-3p 7'-but-3-en-2-yl-7'-(3-phenylmethoxypropyl)spiro[1,3-dioxolane-2,2'-3,4,7a,8,9,10-hexahydro-1h-cyclopenta[i]indolizine]-6'-thione 361486 NSC624523 sensitive
hsa-miR-758-3p 7-[(3-fluorophenyl)methoxy]-9-[(3-fluorophenyl)methyl]-2-[(4-fluorophenyl)methyl]-1-methylpyrido[3,4-b]indol-2-ium 54766740 NSC760181 sensitive
hsa-miR-758-3p 7-hydroxy-2-nonyl-4h-chromen-4-one 5375154 NSC631965 sensitive
hsa-miR-758-3p 8-(6-fluorohexyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;hydrochloride 380336 NSC665863 resistant
hsa-miR-758-3p 8-[3-(1,3-dioxolan-2-yl)-2-(4-fluorophenyl)propyl]-3-ethyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;hydrochloride 380308 NSC665789 resistant
hsa-miR-758-3p 8-aminoadenosine 259812 NSC90394 resistant
hsa-miR-758-3p 8-chloro-7-methyl-5,5-dioxo-n-phenyl-[1,2,4]triazolo[4,3-b][1,4,2]benzodithiazin-3-amine 400657 NSC713019 sensitive
hsa-miR-758-3p 8-chloro-7-methyl-n-(4-methylphenyl)-5,5-dioxo-[1,2,4]triazolo[4,3-b][1,4,2]benzodithiazin-3-amine 400656 NSC713018 sensitive
hsa-miR-758-3p 8-trichloromethyldihydroberberine 320713 NSC269192 sensitive
hsa-miR-758-3p 9-((2-chloroethyl)thio)acridine 395387 NSC699923 resistant
hsa-miR-758-3p 9-(benzylsulfinyl)-2,7-dimethoxyacridine 395397 NSC699933 resistant
hsa-miR-758-3p 9-bromo-2,3-dimethoxy-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one 395805 NSC700693 resistant
hsa-miR-758-3p 9-hydroxy-2-(.beta.-diethylaminoethyl)ellipticinium acetate 72034 NSC311152 sensitive
hsa-miR-758-3p Berberine iodide 72350 NSC150446 sensitive
hsa-miR-758-3p Di-n-octyl-secalonsaure a 430141 NSC268925 sensitive
hsa-miR-758-3p Diaporthein b 54612739 NSC751295 resistant
hsa-miR-758-3p Diethyl (Z)-2-(2,4-dioxo-3-prop-2-ynylpyrimidin-1-yl)but-2-enedioate 5469884 NSC693983 resistant
hsa-miR-758-3p Diethyl 4-hydroxy-2-(4-methoxyphenyl)-6-oxo-4-phenyl-1,3-cyclohexanedicarboxylate 386764 NSC679443 sensitive
hsa-miR-758-3p Ellipticine 3213 NSC71795 sensitive
hsa-miR-758-3p Elliptinium acetate 42722 NSC264137 sensitive
hsa-miR-758-3p Ethyl (E)-3-(6-methoxy-1-thiophen-3-yl-3,4-dihydronaphthalen-2-yl)prop-2-enoate 24205739 NSC736553 sensitive
hsa-miR-758-3p Ethyl 16-(3,4-dimethoxyphenyl)-12,14-diphenyl-10-oxa-3,5,6,8,12,13-hexazatetracyclo[7.7.0.02,6.011,15]hexadeca-1(9),2,4,7,11(15),13-hexaene-4-carboxylate 391836 NSC691424 sensitive
hsa-miR-758-3p Fixierer p 70397 NSC63839 resistant
hsa-miR-758-3p Gtpl10345 378629 NSC661421 resistant
hsa-miR-758-3p Gw701427a 10276395 NSC756323 sensitive
hsa-miR-758-3p Haloprogin 3561 NSC100071 resistant
hsa-miR-758-3p Heteromine a 391982 NSC691767 sensitive
hsa-miR-758-3p Hexyl (e)-3-[(2s,4z)-2-(hydroxymethyl)-4-(4-methyl-3-propan-2-ylpentylidene)-5-oxooxolan-2-yl]prop-2-enoate 5471817 NSC714070 sensitive
hsa-miR-758-3p Hsdb 8106 16129719 NSC676825 resistant
hsa-miR-758-3p Inosine, 6-thio-, 2',3',5'-tripentanoate 4208664 NSC77495 resistant
hsa-miR-758-3p Isobaccharin 5358646 NSC269760 sensitive
hsa-miR-758-3p Isobrucein a 322357 NSC279503 sensitive
hsa-miR-758-3p J3.522.543i 6163542 NSC113053 resistant
hsa-miR-758-3p Kinetin riboside 3832 NSC120958 resistant
hsa-miR-758-3p Kuc100204 378309 NSC660313 sensitive
hsa-miR-758-3p Laurusin 135476719 NSC106486 resistant
hsa-miR-758-3p Maxima isoflavone d 343081 NSC382028 sensitive
hsa-miR-758-3p Mefloquine hydrochloride 456309 NSC157387 resistant
hsa-miR-758-3p Methyl (Z)-4,4-dicyano-4-[(3-methoxyphenyl)methylideneamino]but-2-enoate 5470182 NSC698278 resistant
hsa-miR-758-3p Methyl 4-[3-(2-thienyl)quinoxalin-2-yl]oxybenzoate 388002 NSC682365 sensitive
hsa-miR-758-3p Musennin 267361 NSC106554 sensitive
hsa-miR-758-3p N'-[(Z)-[(4Z)-2-(1,3-benzodioxol-5-yl)-4-[[4-oxo-4-[2-(trifluoromethyl)anilino]butanoyl]hydrazinylidene]chromen-3-ylidene]amino]-N-[2-(trifluoromethyl)phenyl]butanediamide 6399328 NSC641210 sensitive
hsa-miR-758-3p N'-chloro-4-[2-[2-[4-[(Z)-N'-chlorocarbamimidoyl]phenoxy]ethyl-(4-methylphenyl)sulfonylamino]ethoxy]benzenecarboximidamide 45028721 NSC743909 sensitive
hsa-miR-758-3p N-(6-methyl-1,3-benzothiazol-2-yl)-4-naphthalen-2-yl-2,4-dioxo-3-(3-oxo-1h-2-benzofuran-1-yl)butanamide 369455 NSC641225 sensitive
hsa-miR-758-3p N-[(z)-[phenyl(pyridin-2-yl)methylidene]amino]quinoxalin-2-amine 5869744 NSC693626 resistant
hsa-miR-758-3p N-[2-(dimethylamino)ethyl]-4-(furo[3,2-c]quinolin-4-ylamino)benzamide 24204686 NSC732490 resistant
hsa-miR-758-3p N-[2-chloro-5-(trifluoromethyl)phenyl]-4-naphthalen-2-yl-2,4-dioxo-3-(3-oxo-1h-2-benzofuran-1-yl)butanamide 369469 NSC641239 sensitive
hsa-miR-758-3p N-benzyl-1-[10-[4-(benzylamino)-2-methylquinolin-1-ium-1-yl]decyl]-2-methylquinolin-1-ium-4-amine;perchlorate 387881 NSC682094 sensitive
hsa-miR-758-3p N,n-dimethyl-4-[(e)-2-(1-methyl-2,5-diphenylpyrazol-1-ium-3-yl)ethenyl]aniline;trifluoromethanesulfonate 5469868 NSC693576 sensitive
hsa-miR-758-3p None 12201866 NSC179207 resistant
hsa-miR-758-3p NSC644919 NSC644919 sensitive
hsa-miR-758-3p NSC699071 NSC699071 sensitive
hsa-miR-758-3p NSC751830 NSC751830 resistant
hsa-miR-758-3p Oxidanium;1,3-diphenylpropane-1,3-dione;neodymium(3+);hydroxide 24202397 NSC647042 sensitive
hsa-miR-758-3p Phenoxathiin-2-ylmethyl carbamimidothioate;hydrochloride 392088 NSC691900 resistant
hsa-miR-758-3p Phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) 10714966 NSC289922 sensitive
hsa-miR-758-3p Propan-2-ylsulfanyl-(2,3,5,6-tetrachloropyridin-4-yl)sulfanylmethanethione 399833 NSC710969 resistant
hsa-miR-758-3p Protein: pahiv4 NSC678525 sensitive
hsa-miR-758-3p Pyrazolanthrone 8515 NSC75890 resistant
hsa-miR-758-3p Pyrimido[5,4-g]pteridine-2,4,6,8(1h,3h,7h,9h)-tetrone, 1,9-bis(methoxymethyl)-3,7-dimethyl-, 5-oxide 385097 NSC676032 sensitive
hsa-miR-758-3p Sarcoviolin 24202820 NSC726045 sensitive
hsa-miR-758-3p Stl298328 387753 NSC681782 resistant
hsa-miR-758-3p Stl323035 383655 NSC672073 sensitive
hsa-miR-758-3p Stl361983 256661 NSC83715 resistant
hsa-miR-758-3p Tetramethyl (1r,5r,6s,9s)-7-[4-[(e)-2,3-bis(4-chlorophenyl)prop-2-enoyl]oxyphenyl]-3,5-dihydroxybicyclo[3.3.1]non-2-ene-2,4,6,9-tetracarboxylate 54681588 NSC717067 resistant
hsa-miR-758-3p Tris(1,10-phenanthroline)lanthanum(iii)-trithiocyanate 24202211 NSC632737 resistant
hsa-miR-758-3p Xestin a 5352066 NSC647638 resistant
hsa-miR-758-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-758-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-758-3p Etoposide 36462 NSC141540 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-758-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive Low Esophageal Cancer cell line (ECA-109)
hsa-miR-758-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-758-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-758-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-758-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-758-3p Paclitaxel 36314 NSC125973 approved resistant cell line (HeyA8)
hsa-miR-758-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-miR-758-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-758-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM47)
hsa-miR-758-3p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-758-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-758-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (K562)
hsa-miR-758-3p Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR70)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-758-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-758-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVCAR3)
hsa-miR-758-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

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