miRTarBase - #MIRT439749


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pre-miRNA Information
pre-miRNA hsa-mir-127   
Genomic Coordinates chr14: 100882979 - 100883075
Description Homo sapiens miR-127 stem-loop
Comment This miRNA sequence is predicted based on homology to a verified miRNA from mouse .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-127-5p
Sequence 23| CUGAAGCUCAGAGGGCUCUGAU |44
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM9722115 13 COSMIC
COSM7115045 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs867796380 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ROGDI   
Synonyms KTZS
Description rogdi homolog
Transcript NM_024589   
Expression
Putative miRNA Targets on ROGDI
3'UTR of ROGDI
(miRNA target sites are highlighted)		 
>ROGDI|NM_024589|3'UTR
   1 TCACAGCACCCAGGAGCTTGTCTCCAGGAAGGCGGCCCCGTCCCCTACTCATACCCACCACAGAGCACCAGCCAGTGCCA
  81 ACGCCAGGCTGCTATTTATCTCCCTATCCCACCCCCTACCCCACCTAACACATTTGCACTGCCGGGAATGGACACTGGAA
 161 GTGCCAGGAGGAAGGAAGGCTGGTTTGGTGGGGTAGTGGGGAGGTCAGGGAGGCGGGGCCAAGGGTGTCCCACATTCCCA
 241 ACACCGCCCTCTGATCACCATGGGAATCTTTGGACTCAGGACAGGGCCAGGCGCAGGGCTCTCCCTCCTCTCCCCTTCGC
 321 TGTCCCCTCCCCCTGGAGGGCATGGTGTCGGGGGGTGGCACTGAGCTATGAGTCCCGGGGATGGTGAGGAACGCCACAGA
 401 CAGAGCCACCCTAGGAGTGAGTATAGTGCTGGTGACTGTGTTTCATAGCCCCAGTCCAGGGCTGTCTAAGAAATAAAGAT
 481 CATCAGACTCCACCTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaGUCUCG-GGAGACUCGAAguc 5'
            || ||| ||   ||||||   
Target 5' -tCACAGCACCCAGGAGCTTgtc 3'
 1 - 22 120.00 -13.82
2 
miRNA  3' uaGUCUCGGGA-----GACUCGAAGUc 5'
            :| ||: ||     ||| |:|||| 
Target 5' agTATAGTGCTGGTGACTGTGTTTCAt 3'
 420 - 446 112.00 -10.50
3 
miRNA  3' uaGUCUCGG---GAGACUCGA-AGuc 5'
            |||:|||   | | |:||| ||  
Target 5' gaCAGGGCCAGGCGCAGGGCTCTCcc 3'
 280 - 305 100.00 -19.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
886971 24 ClinVar
885973 44 ClinVar
885972 54 ClinVar
319397 112 ClinVar
319396 144 ClinVar
885971 208 ClinVar
885970 246 ClinVar
319395 270 ClinVar
319394 292 ClinVar
885049 298 ClinVar
319393 347 ClinVar
319392 355 ClinVar
319391 380 ClinVar
319390 451 ClinVar
319389 454 ClinVar
COSN30492556 33 COSMIC
COSN31613370 36 COSMIC
COSN30193155 50 COSMIC
COSN30101078 53 COSMIC
COSN30458988 70 COSMIC
COSN31512925 83 COSMIC
COSN31588208 121 COSMIC
COSN28675319 144 COSMIC
COSN32076706 178 COSMIC
COSN21353035 206 COSMIC
COSN30139429 215 COSMIC
COSN32058597 395 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1374290381 2 dbSNP
rs1217370537 7 dbSNP
rs746123915 8 dbSNP
rs1441485886 9 dbSNP
rs779326500 10 dbSNP
rs757087992 14 dbSNP
rs568221664 15 dbSNP
rs777841751 19 dbSNP
rs756091670 24 dbSNP
rs1487393784 27 dbSNP
rs1417494356 28 dbSNP
rs752084585 33 dbSNP
rs202112305 34 dbSNP
rs367877060 39 dbSNP
rs370088479 40 dbSNP
rs376812863 42 dbSNP
rs1185925248 43 dbSNP
rs200440067 44 dbSNP
rs1448747163 46 dbSNP
rs1264000130 47 dbSNP
rs929049648 48 dbSNP
rs377528404 50 dbSNP
rs764440999 53 dbSNP
rs76593206 54 dbSNP
rs775622307 54 dbSNP
rs761273594 55 dbSNP
rs1313095349 56 dbSNP
rs772169351 57 dbSNP
rs1344124109 60 dbSNP
rs759731200 65 dbSNP
rs774710346 67 dbSNP
rs1326435654 68 dbSNP
rs771338314 69 dbSNP
rs749034241 70 dbSNP
rs1336238391 71 dbSNP
rs1239346998 72 dbSNP
rs777718834 75 dbSNP
rs1376875579 78 dbSNP
rs947409781 79 dbSNP
rs769581748 82 dbSNP
rs748143519 83 dbSNP
rs1424917589 84 dbSNP
rs781044131 86 dbSNP
rs1476689822 87 dbSNP
rs1263934259 89 dbSNP
rs1193013428 90 dbSNP
rs975501473 94 dbSNP
rs1259867295 98 dbSNP
rs1440775224 100 dbSNP
rs1178579350 101 dbSNP
rs754503264 102 dbSNP
rs565807247 103 dbSNP
rs1388547327 109 dbSNP
rs942816377 110 dbSNP
rs912753417 111 dbSNP
rs886052036 112 dbSNP
rs1471150340 113 dbSNP
rs552155335 114 dbSNP
rs951646609 115 dbSNP
rs78649123 116 dbSNP
rs1396966897 118 dbSNP
rs973760729 118 dbSNP
rs1445850321 119 dbSNP
rs563680803 120 dbSNP
rs1329225728 121 dbSNP
rs977511014 123 dbSNP
rs967880629 124 dbSNP
rs1023308719 126 dbSNP
rs1475456393 130 dbSNP
rs1253385063 131 dbSNP
rs1011966311 142 dbSNP
rs1014820058 143 dbSNP
rs7546 144 dbSNP
rs530258770 146 dbSNP
rs1470258145 149 dbSNP
rs1191219636 154 dbSNP
rs551438150 155 dbSNP
rs1172073673 158 dbSNP
rs1423982299 167 dbSNP
rs1027751266 170 dbSNP
rs993230917 171 dbSNP
rs897555304 173 dbSNP
rs1441583603 176 dbSNP
rs1294115779 179 dbSNP
rs902421684 188 dbSNP
rs1385215559 198 dbSNP
rs541234319 209 dbSNP
rs1318920518 210 dbSNP
rs888959454 214 dbSNP
rs370414913 215 dbSNP
rs935940459 217 dbSNP
rs1222966049 221 dbSNP
rs1265430819 229 dbSNP
rs1487217437 237 dbSNP
rs893155373 238 dbSNP
rs1263430098 245 dbSNP
rs1039786573 246 dbSNP
rs1191191707 248 dbSNP
rs1419762030 253 dbSNP
rs1405821514 257 dbSNP
rs76192577 270 dbSNP
rs1456427130 273 dbSNP
rs946093210 284 dbSNP
rs770358012 286 dbSNP
rs1300168168 289 dbSNP
rs917319617 291 dbSNP
rs8118 292 dbSNP
rs545854112 298 dbSNP
rs958826246 303 dbSNP
rs1229319156 308 dbSNP
rs1226239577 315 dbSNP
rs754421881 318 dbSNP
rs930174061 325 dbSNP
rs918808740 329 dbSNP
rs974739197 330 dbSNP
rs1214015473 335 dbSNP
rs1450668636 336 dbSNP
rs1472999794 338 dbSNP
rs952952714 342 dbSNP
rs1357714712 344 dbSNP
rs1420829305 345 dbSNP
rs117730440 347 dbSNP
rs1361263289 349 dbSNP
rs375211089 350 dbSNP
rs1296579741 351 dbSNP
rs886052035 355 dbSNP
rs1410237442 356 dbSNP
rs897527219 356 dbSNP
rs990470313 357 dbSNP
rs960431144 358 dbSNP
rs1242961203 360 dbSNP
rs1008607007 364 dbSNP
rs1352309076 368 dbSNP
rs1166215233 370 dbSNP
rs1448325059 374 dbSNP
rs557318424 376 dbSNP
rs1235553899 377 dbSNP
rs888926775 377 dbSNP
rs1481536789 379 dbSNP
rs3210637 380 dbSNP
rs935865854 383 dbSNP
rs904421384 385 dbSNP
rs1439133314 390 dbSNP
rs1156985405 391 dbSNP
rs565123612 392 dbSNP
rs1415292248 393 dbSNP
rs946032030 394 dbSNP
rs1357795522 395 dbSNP
rs966953175 395 dbSNP
rs765975136 399 dbSNP
rs1022182410 400 dbSNP
rs544857108 402 dbSNP
rs937425606 405 dbSNP
rs1237295893 407 dbSNP
rs1277013360 411 dbSNP
rs554770999 414 dbSNP
rs984273424 416 dbSNP
rs1341500309 423 dbSNP
rs1293140949 424 dbSNP
rs1199082937 426 dbSNP
rs1237472723 430 dbSNP
rs900443743 436 dbSNP
rs952879265 442 dbSNP
rs1248536542 444 dbSNP
rs1478448444 448 dbSNP
rs1377601382 450 dbSNP
rs886052034 451 dbSNP
rs74733389 452 dbSNP
rs540581745 454 dbSNP
rs1171888501 460 dbSNP
rs973040679 461 dbSNP
rs1006928118 464 dbSNP
rs1045939 466 dbSNP
rs1018633590 476 dbSNP
rs189197723 478 dbSNP
rs1365599152 486 dbSNP
rs953121647 491 dbSNP
rs377216620 493 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions islets
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO. ...

- Kameswaran V; Bramswig NC; McKenna LB; Penn et al., 2014, Cell metabolism.

Article - Kameswaran V; Bramswig NC; McKenna LB; Penn et al.
- Cell metabolism, 2014
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing beta cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the pathogenesis of human T2DM, we sequenced the small RNAs of human islets from diabetic and nondiabetic organ donors. We identified a cluster of microRNAs in an imprinted locus on human chromosome 14q32 that is highly and specifically expressed in human beta cells and dramatically downregulated in islets from T2DM organ donors. The downregulation of this locus strongly correlates with hypermethylation of its promoter. Using HITS-CLIP for the essential RISC-component Argonaute, we identified disease-relevant targets of the chromosome 14q32 microRNAs, such as IAPP and TP53INP1, that cause increased beta cell apoptosis upon overexpression in human islets. Our results support a role for microRNAs and their epigenetic control by DNA methylation in the pathogenesis of T2DM.
LinkOut: [PMID: 24374217]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.58 1.5e-3 0.562 2.1e-3 24 Click to see details
GSE28260 Renal cortex and medulla -0.604 1.4e-2 -0.648 8.3e-3 13 Click to see details
GSE38226 Liver fibrosis -0.347 6.2e-2 -0.326 7.5e-2 21 Click to see details
GSE19536 Breast cancer -0.122 1.1e-1 -0.113 1.3e-1 100 Click to see details
GSE19783 ER- ER- breast cancer -0.122 1.4e-1 -0.098 2.0e-1 79 Click to see details
GSE19350 CNS germ cell tumors -0.285 1.8e-1 -0.112 3.6e-1 12 Click to see details
GSE21687 Ependynoma primary tumors 0.099 2.2e-1 -0.004 4.9e-1 64 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.173 2.3e-1 0.107 3.3e-1 20 Click to see details
GSE42095 Differentiated embryonic stem cells -0.135 2.7e-1 -0.255 1.2e-1 23 Click to see details
GSE17498 Multiple myeloma 0.077 3.2e-1 0.078 3.2e-1 40 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.087 3.4e-1 -0.292 7.8e-2 25 Click to see details
GSE32688 Pancreatic cancer -0.072 3.5e-1 -0.021 4.5e-1 32 Click to see details
GSE19783 ER+ ER+ breast cancer -0.088 3.6e-1 -0.153 2.6e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.001 5.0e-1 0.265 1.1e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells -0.001 5.0e-1 0.265 1.1e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD -0.46 0 -0.390 0.01 32 Click to see details
CHOL -0.754 0.01 -0.750 0.01 9 Click to see details
KIRP -0.406 0.01 -0.409 0.01 32 Click to see details
COAD 0.697 0.03 0.667 0.04 8 Click to see details
PAAD 0.837 0.08 0.800 0.1 4 Click to see details
PCPG 0.962 0.09 1.000 0.5 3 Click to see details
LUSC 0.215 0.1 0.292 0.04 38 Click to see details
KICH -0.262 0.1 -0.205 0.16 25 Click to see details
BRCA 0.128 0.12 0.151 0.09 84 Click to see details
THCA -0.147 0.13 -0.095 0.24 59 Click to see details
CESC 0.913 0.13 1.000 0.5 3 Click to see details
KIRC -0.134 0.14 -0.166 0.09 68 Click to see details
PRAD 0.075 0.3 0.045 0.38 50 Click to see details
BLCA -0.129 0.3 -0.183 0.23 18 Click to see details
UCEC 0.124 0.31 0.226 0.18 19 Click to see details
ESCA 0.169 0.31 0.191 0.29 11 Click to see details
HNSC 0.078 0.31 0.137 0.19 42 Click to see details
LIHC -0.059 0.34 -0.058 0.35 49 Click to see details
LUAD 0.042 0.45 -0.042 0.45 12 Click to see details
LUAD 0.042 0.45 -0.042 0.45 12 Click to see details
LUAD 0.042 0.45 -0.042 0.45 12 Click to see details
113 hsa-miR-127-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT380928 ZNF264 zinc finger protein 264 2 2
MIRT439324 USP34 ubiquitin specific peptidase 34 1 1
MIRT439333 USP22 ubiquitin specific peptidase 22 1 1
MIRT439379 TTC37 tetratricopeptide repeat domain 37 1 1
MIRT439445 TMEM116 transmembrane protein 116 1 1
MIRT439498 SYNJ2 synaptojanin 2 1 1
MIRT439525 STBD1 starch binding domain 1 1 1
MIRT439562 SORL1 sortilin related receptor 1 1 1
MIRT439660 SF3B1 splicing factor 3b subunit 1 1 1
MIRT439749 ROGDI rogdi homolog 1 1
MIRT439836 RAB3B RAB3B, member RAS oncogene family 1 1
MIRT439923 PPL periplakin 1 1
MIRT439963 PKD1 polycystin 1, transient receptor potential channel interacting 1 1
MIRT439985 PHKG2 phosphorylase kinase catalytic subunit gamma 2 1 1
MIRT440029 PCLO piccolo presynaptic cytomatrix protein 1 1
MIRT440179 MTRNR2L8 MT-RNR2-like 8 1 1
MIRT440183 MTRNR2L4 MT-RNR2-like 4 1 1
MIRT440184 MTRNR2L6 MT-RNR2-like 6 1 1
MIRT440194 MTRNR2L1 MT-RNR2-like 1 1 1
MIRT440269 MBP myelin basic protein 1 1
MIRT440323 LIN7C lin-7 homolog C, crumbs cell polarity complex component 1 1
MIRT440331 LGALS8 galectin 8 1 1
MIRT440355 KLHL29 kelch like family member 29 1 1
MIRT440397 KDM6B lysine demethylase 6B 1 1
MIRT440411 KAT2B lysine acetyltransferase 2B 1 1
MIRT440424 ITCH itchy E3 ubiquitin protein ligase 1 1
MIRT440651 FBXO7 F-box protein 7 1 1
MIRT440773 DST dystonin 1 1
MIRT440824 DGKD diacylglycerol kinase delta 1 1
MIRT440914 COPA coatomer protein complex subunit alpha 1 1
MIRT441118 BBS4 Bardet-Biedl syndrome 4 1 1
MIRT441153 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 1 1
MIRT441193 ARID1A AT-rich interaction domain 1A 1 1
MIRT441260 ADM adrenomedullin 1 1
MIRT441282 ACTB actin beta 1 1
MIRT441306 ABHD2 abhydrolase domain containing 2 1 1
MIRT441860 TEX35 testis expressed 35 2 2
MIRT442190 CCDC132 VPS50, EARP/GARPII complex subunit 2 2
MIRT442886 RHCG Rh family C glycoprotein 2 2
MIRT444158 ZNF701 zinc finger protein 701 2 2
MIRT444506 ZNF525 zinc finger protein 525 2 2
MIRT444770 NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2 2
MIRT445830 SRSF11 serine and arginine rich splicing factor 11 2 2
MIRT445850 LRRC1 leucine rich repeat containing 1 2 2
MIRT445863 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT446161 C8A complement C8 alpha chain 2 2
MIRT447117 SLFN5 schlafen family member 5 2 2
MIRT447990 CDX1 caudal type homeobox 1 2 2
MIRT449032 ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 2 2
MIRT449295 SMIM19 small integral membrane protein 19 2 2
MIRT449541 PCDH9 protocadherin 9 2 2
MIRT449579 ZNF510 zinc finger protein 510 2 2
MIRT450062 SYT9 synaptotagmin 9 2 2
MIRT450437 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 2
MIRT450449 ZDHHC2 zinc finger DHHC-type containing 2 2 2
MIRT450695 RORA RAR related orphan receptor A 2 2
MIRT453654 RAB6C RAB6C, member RAS oncogene family 2 2
MIRT463771 YOD1 YOD1 deubiquitinase 2 2
MIRT468425 SETD1B SET domain containing 1B 2 2
MIRT468843 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT475594 HMGB2 high mobility group box 2 4 4
MIRT478284 DDX19A DEAD-box helicase 19A 2 2
MIRT487594 NKD2 naked cuticle homolog 2 2 4
MIRT493440 KANSL1 KAT8 regulatory NSL complex subunit 1 2 6
MIRT496169 RPL35A ribosomal protein L35a 2 4
MIRT497566 CCR6 C-C motif chemokine receptor 6 2 2
MIRT497917 BTG1 BTG anti-proliferation factor 1 2 2
MIRT498331 PRELID2 PRELI domain containing 2 2 2
MIRT498369 KLHL11 kelch like family member 11 2 2
MIRT498856 LITAF lipopolysaccharide induced TNF factor 2 2
MIRT505640 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT506128 PLRG1 pleiotropic regulator 1 2 4
MIRT512242 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT512489 ARID2 AT-rich interaction domain 2 2 2
MIRT525251 RNF213 ring finger protein 213 2 2
MIRT530197 ALX1 ALX homeobox 1 2 4
MIRT530551 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 2
MIRT534048 STC2 stanniocalcin 2 2 2
MIRT537508 FAM105A family with sequence similarity 105 member A 2 2
MIRT543005 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT543814 SNX10 sorting nexin 10 2 2
MIRT549303 ARID5B AT-rich interaction domain 5B 2 2
MIRT549407 ADIPOR2 adiponectin receptor 2 2 4
MIRT550547 ARSK arylsulfatase family member K 2 2
MIRT554319 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT554515 RUFY2 RUN and FYVE domain containing 2 2 2
MIRT559603 AMOT angiomotin 2 2
MIRT564844 ZBED3 zinc finger BED-type containing 3 2 2
MIRT566125 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT567484 FOXK1 forkhead box K1 2 2
MIRT576521 Txlna taxilin alpha 2 2
MIRT633635 CASC5 kinetochore scaffold 1 2 2
MIRT639325 C9orf41 carnosine N-methyltransferase 1 2 2
MIRT643174 MDM2 MDM2 proto-oncogene 2 2
MIRT651214 ZNF225 zinc finger protein 225 2 2
MIRT653039 STRIP2 striatin interacting protein 2 2 2
MIRT653042 STOX2 storkhead box 2 2 2
MIRT658769 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT666728 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT681223 DUSP19 dual specificity phosphatase 19 2 2
MIRT685562 SRD5A3 steroid 5 alpha-reductase 3 2 2
MIRT687434 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT688439 DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 2 2
MIRT692707 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT700552 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT704955 CBX2 chromobox 2 2 2
MIRT714524 ALKBH3 alkB homolog 3, alpha-ketoglutaratedependent dioxygenase 2 2
MIRT716225 DGKI diacylglycerol kinase iota 2 2
MIRT717953 MIA3 MIA family member 3, ER export factor 2 2
MIRT719902 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT732044 BLVRB biliverdin reductase B 3 1
MIRT733622 SNX5 sorting nexin 5 3 0
MIRT737210 CXCR4 C-X-C motif chemokine receptor 4 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-127 17beta-estradiol (E2) approved 5757 Quantitative real-time PCR rat breast 17700064 2007 down-regulated
miR-127 5-aza-2'-deoxycytidine (5-Aza-CdR) + 4-phenylbutyric acid (PBA) NULL NULL Microarray T24 human bladder cancer cells 16766263 2006 up-regulated
miR-127 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
miR-127-5p Glucose NULL 5793 Microarray endothelial cells 24394957 2014 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-127 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-mir-127 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-127-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-127-5p Palbociclib 5330286 NSC758247 approved resistant cell line (T47D)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-127-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM11)
hsa-miR-127-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-127-5p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-127-5p Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-127-5p Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR200)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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