miRTarBase - #MIRT440005


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pre-miRNA Information
pre-miRNA hsa-mir-412   
Genomic Coordinates chr14: 101065447 - 101065537
Synonyms MIRN412, hsa-mir-412, MIR412
Description Homo sapiens miR-412 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-412-3p
Sequence 54| ACUUCACCUGGUCCACUAGCCGU |76
Evidence Not_experimental
Experiments
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
rs61992671 18 GWAS
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs369997462 1 dbSNP
rs1439693090 7 dbSNP
rs1301668924 11 dbSNP
rs534204576 13 dbSNP
rs775386036 14 dbSNP
rs762832140 15 dbSNP
rs1203323285 16 dbSNP
rs61992671 18 dbSNP
rs1022012324 19 dbSNP
rs1207609936 20 dbSNP
rs139967426 21 dbSNP
rs539487075 22 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PEG3   
Synonyms PW1, ZKSCAN22, ZNF904, ZSCAN24
Description paternally expressed 3
Transcript NM_001146184   
Other Transcripts NM_001146185 , NM_001146186 , NM_001146187 , NM_006210   
Expression
Putative miRNA Targets on PEG3
3'UTR of PEG3
(miRNA target sites are highlighted)		 
>PEG3|NM_001146184|3'UTR
   1 GGGCATGGGGTAAAGGTTAGAAAACCTTCACCTAGGACTTGACCCTTACCAAACCACAGAGAATCCAAACCAATCCATGA
  81 TAATGTCAGTAGGAGACTTAACCTTAGTGTGTTACACACCTGACTTAACATCTCTAAACTCAGATTGAAAAGAGACCGAA
 161 TGTGCAGATTCCACAGTCTTAAGCTTTCCCCTTCAGATGTCAGTGTCTGCATGTGGGAAAGCCATAGCACACATCTTACC
 241 TTTCCAAGTAATCAGATTGAGAAAACCCTATGAGTATTCCAGACTACAGAGTTTGCCCAAATCAACTGTAAATGACACTT
 321 GTGTAACGTATATATAGTGTTTCATGAGGTGTATATAAAATAGCAAATTATGACAGAACAGTGATCACATATATTTGGAT
 401 TTATATGATATACAGTTACAGTTTACTCTGCAGAGGTACCTTACCTGGTATTCTTTGAATTTTTTTTTTTTTTGGAGGAG
 481 GAAGAGAGCAACAAATTTGATTATATTTTTAAGTGTCTTAGATCCTGAGAAAGATTTATTGTGCATTATTTGAACCCTGT
 561 CAATATCTTTTTGAGTAATTGTTTTGTTTCTTACCCTTAAATAGTCTTGTGAAGCTGTAGGCATGATAGATAACATGGCT
 641 TTTACTCCTTACTGTTTGAAAAGATAAGTACTTTAGCTTCTTTCTGCAGCCATTTCATCTGCGCCAACACTTTGGAACCT
 721 AATACTGTGTAAGGCTTTACAATATACGGATTGGCTTTTTGTGACCCAGATTGATTGGTTGCCACATGTTATGTTTGTTG
 801 AAGTGGTTCTCATGCAAAAATATTACACATTTGTGTTCTGGGTTTTTTTTTTTTTTAACCAACTCAATATGTGTTTGATG
 881 ATAGTGAATTGATAAAACCCGAAGCTTTTCCCTGTAAATCTTACATCTTTGCCTTTAAAGAATGGGTTACAACCATCACT
 961 AGATCACAGTAGTGCCTAATGAAGGTTGAGAACCGTAGGAGAGGCTCTCATGCTGTAAATAATGTTGCAGGCTAATAACC
1041 TTTCATCACTTCCTTTGTGCGCTTCCTGCCTTAAGTGACAAGTAGCAACATGGCTTGGGTCCCCTGTGCAGCATCAGCTT
1121 ATGCTGCCACAAGTCAGTTTGCACCCTAGGTGCCCAGGAGCTAGTATCCTTAGATCTTTCTATCGCTAACTTAATTCTCT
1201 TCGTTATTTATCTGACCCTCTAACTCCATGTCTAACTTGCATTAAAAAAAAAAAAATTCTTTACAGTCAACCCAAGCTTA
1281 ACATGGACTCAGGTTCCCCAGCAGCCTTAATTTGTTTTGTTAACATCTGTTCCTTCTTTTTCAGCTCTCCTAGAGTATTT
1361 CTGAGTGTTGTGTTCATCTAATCTTAGTATTCTTTTAATTACAAATTGACCTCACAGCTTGAGGTTTCTTGTGTCCTATT
1441 CTGTGGACTACCTGTGCTCCTTTGCTTCCCCTCCCCTCGCATAATAACTATATTAAGAAATTTTTTTTGGCCTTGAGTTG
1521 GCTGGAAAAAAAATATAAAATTTAAAAAATTTAAAAAAAAAGATTTGCAAAATGTAAGTGTAGATCATTTGAACAAGCAA
1601 AATTAAAGTACCCACTGGGGGAAATGTGTCTGAATCTTACTCTTCTGGATCTGCAGGATTAGGGCTTGGAAGTATGTCAA
1681 AGATGCAGGGAGTGTCAAAGTTTAGGAAGATTGTAGAGCTGAGAGCAAGAAGCAGAAATGAGTGAGTCAAAGAAGGGAGT
1761 CCTAATATATCACCAGATCTAGGAGGGGAGAGGAGACAGACAGAAGAAAACACCAGAGGCAAGAACTGTAGAAGGCCAGG
1841 TTTCTGAGAATGAATTGAGCGGGGTGTCCTGAGCAGTTTGGAAAAGGAGTTTTTGATGGTATGGTGTAGGTGAGGGCTGG
1921 CTGCATAGGAAGGACTGAGGTTGGAACGGACATCGGGAAAGCTGAGGGGCAGTGAGGTTTACTACATGGGAAAAGGACTC
2001 TTGAAACGAGAATCAGTGTTGATGTCGGGGTGAACTTTGTGGGTACATTACTTGGTGTTAACATTGTTGGCAGTGGTAGC
2081 CCCTTTTCAGAAAGCAACTTGCTGTAAGTCAGGGTGTCCGTTCCAACCTTCAGCTAGTGAAAAGGTAGTAACAAATGGTA
2161 AACAAGAGAATGATTGTTTAAACCTATCTGTGGACACTTAATGCAACTGTTTAAAAATGATAATCACGAGTTATGTAGCA
2241 ACGTGGAAATATATTTACAGAACATTAAGTGGAGAAAGCAGGACACGAAAGTATATTTATACTACAGTTATAACTCAACA
2321 GTTCATTTATATGCTGTTCATTTAACAGTTCATTTAAACAGTTCATTATAACTGTTTAAAAATATATATGCTTATAGTCA
2401 AAAGCTGTTGTGGTGTTGTTGTTGTAGGCTTATAGTTGAGCATTATTTTCTTAAATTTCTTGAATGTTCTTTATGGTAGT
2481 GTTACTAAAAAGTTTATGATCACATTTTCATTGTGAACATAATTTGAACTCATTATCACACACTTGGAAAATACAGAAAA
2561 GTGGAGGAAAAAAAATCATATCCCCACCATCCAAAGACATATACTCTCCTCTTATCTTGTTCATTCTTGTTTCTGTGCAC
2641 AGGTTTATGATTATAACTGTGTCAAAATGTATATTCAAAATAGCTGTTACATTACCTTTGTGGAATTATGGTTAAATACT
2721 TTCACTTTAATTTTTTCAAATGTTCCCTATAATAATGTCCTGATAACAGTGTATTATGTGTGTCTCCATTGGTGTGCATA
2801 ATACATACCCAGAGGAAAAATTAGAAAATAAAGTAAATTATTTTAAAAAATTACCTATATTCCCAACACCTAACAACTAC
2881 TGCTAACATCTTGATCTGTTTCCTCTATCTTGTTTCAGTGCACACGCTTGTGATAACAGTGTTAAATATGTGTGCATAAA
2961 GTCTTAAATGAAAAGATGTGGAAAATAACTAAAATAGTGTTGTCATTGTGGGAATTTGGTTAAATATTTTGTCTCAAATT
3041 CCTTAAATAATCTTTGGTGTTTTGGTAATAAATTTTATGTATGTATTTTCCATTACAAATATAATACATACTCATACAAA
3121 ACTTTGGAAATTCAGTAAAGAAAATTCACACATATTCCCAACACCCAACAACAATTAACTGTTAACATCTTGATCTGTGC
3201 ACTAGTCTGTGATTATTAGGGTGTTAGTGATAAGTATGCATAAATGTCAAAGATGGGAAGAAAGATGAAAAACAAGAAAT
3281 AGTTGTGTGGTTGTTGTGGGATTATGGTTATTTTGTTTCGGTTTCCTTGAAAGGTCATCATTCTAGTGTTTTGGTAGTCC
3361 ACCTTTACTACATATATTTCCATTATATATGAAATGTGTTCATTATAGAAACTTTGAAGTTACAGAAATGTAGAAGAGAA
3441 ACTCACCCATGTTTTCACCATCCAAAGAGTGTGGTTAACATCTTGATATATTTTCTTCATCTTGTTTCTGTGCACAGGTT
3521 TTTGGTTTGTTAATATGGTTGTGGTCATTCTATCTGTAATAGTGTCAACAATAAAAATAAAGTTAAAAATAAATATTTAA
3601 AAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugcCGAUCACCUGGUCCACUUCa 5'
             | || |||  :||||||:| 
Target 5' gatGGTA-TGGTGTAGGTGAGGg 3'
 1895 - 1916 143.00 -20.80
2 
miRNA  3' ugcCGAUCACCUGGUCCACUUca 5'
             |:|: | | | :||||||  
Target 5' agtGTTGAT-GTCGGGGTGAAct 3'
 2015 - 2036 131.00 -10.80
3 
miRNA  3' ugccgaucaccuggucCACUUCa 5'
                          |||||| 
Target 5' acccttaaatagtcttGTGAAGc 3'
 593 - 615 120.00 -8.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30464272 7 COSMIC
COSN30458500 8 COSMIC
COSN30469514 12 COSMIC
COSN30148814 20 COSMIC
COSN30151106 20 COSMIC
COSN30511180 26 COSMIC
COSN31524980 38 COSMIC
COSN13838685 39 COSMIC
COSN30156796 41 COSMIC
COSN31500115 44 COSMIC
COSN1082537 61 COSMIC
COSN30523726 61 COSMIC
COSN31578617 97 COSMIC
COSN28732243 108 COSMIC
COSN8606610 154 COSMIC
COSN31577963 157 COSMIC
COSN216866 186 COSMIC
COSN31584118 195 COSMIC
COSN30574709 319 COSMIC
COSN9852723 320 COSMIC
COSN27392586 458 COSMIC
COSN28701848 634 COSMIC
COSN30433195 639 COSMIC
COSN31590733 644 COSMIC
COSN28800064 703 COSMIC
COSN31591145 741 COSMIC
COSN22388656 822 COSMIC
COSN8976783 838 COSMIC
COSN30691324 839 COSMIC
COSN27277526 843 COSMIC
COSN30588956 843 COSMIC
COSN30597851 945 COSMIC
COSN28185651 950 COSMIC
COSN24306650 1022 COSMIC
COSN28638116 1039 COSMIC
COSN31538627 1060 COSMIC
COSN25054878 1104 COSMIC
COSN31577408 1169 COSMIC
COSN20116125 1243 COSMIC
COSN27341238 1244 COSMIC
COSN14657859 1259 COSMIC
COSN8976782 1549 COSMIC
COSN21674595 1553 COSMIC
COSN27657399 1591 COSMIC
COSN27672937 1591 COSMIC
COSN17246355 1831 COSMIC
COSN14591098 1860 COSMIC
COSN29363735 1860 COSMIC
COSN22697128 1879 COSMIC
COSN15976840 1955 COSMIC
COSN23760215 2364 COSMIC
COSN21511303 2407 COSMIC
COSN17882626 2475 COSMIC
COSN1772573 2568 COSMIC
COSN23524424 2572 COSMIC
COSN7450664 2592 COSMIC
COSN20116121 2606 COSMIC
COSN22433866 2845 COSMIC
COSN20966802 2926 COSMIC
COSN8754390 3371 COSMIC
COSN29403925 3516 COSMIC
COSN15680240 3525 COSMIC
COSN26099543 3573 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1284260452 1 dbSNP
rs763577550 2 dbSNP
rs1453922125 7 dbSNP
rs911500358 8 dbSNP
rs770291543 15 dbSNP
rs1469266180 16 dbSNP
rs762814539 17 dbSNP
rs1383221103 20 dbSNP
rs1277345455 21 dbSNP
rs775110506 25 dbSNP
rs368764800 26 dbSNP
rs777043046 28 dbSNP
rs922936061 31 dbSNP
rs770554190 32 dbSNP
rs1345156578 34 dbSNP
rs1304923154 37 dbSNP
rs374250449 42 dbSNP
rs961808552 44 dbSNP
rs1325714281 46 dbSNP
rs777193370 48 dbSNP
rs1001644049 49 dbSNP
rs1383768468 50 dbSNP
rs1431109771 59 dbSNP
rs539238902 71 dbSNP
rs1323734899 72 dbSNP
rs1171906280 76 dbSNP
rs1006037218 79 dbSNP
rs1410602737 81 dbSNP
rs571182889 104 dbSNP
rs1330899697 105 dbSNP
rs1368961971 108 dbSNP
rs878863696 112 dbSNP
rs557805153 115 dbSNP
rs1221388603 134 dbSNP
rs1409387604 136 dbSNP
rs951944282 149 dbSNP
rs1304163707 156 dbSNP
rs1347735245 157 dbSNP
rs1231763449 158 dbSNP
rs188136291 159 dbSNP
rs1288893810 161 dbSNP
rs995547300 162 dbSNP
rs1271803417 174 dbSNP
rs1225463760 176 dbSNP
rs1012587801 185 dbSNP
rs896448433 191 dbSNP
rs866118410 194 dbSNP
rs1449643227 197 dbSNP
rs1056910323 211 dbSNP
rs10422611 213 dbSNP
rs902629495 216 dbSNP
rs1373581638 217 dbSNP
rs549199414 220 dbSNP
rs1476317452 229 dbSNP
rs1170587779 233 dbSNP
rs1388358213 239 dbSNP
rs1407067926 244 dbSNP
rs1043899450 252 dbSNP
rs1338954815 254 dbSNP
rs760388990 257 dbSNP
rs775223474 259 dbSNP
rs535693354 265 dbSNP
rs1385447847 267 dbSNP
rs767080868 270 dbSNP
rs1008457541 271 dbSNP
rs569954278 272 dbSNP
rs550136201 273 dbSNP
rs1294824563 274 dbSNP
rs891319223 279 dbSNP
rs530908281 281 dbSNP
rs759045787 286 dbSNP
rs1293487449 289 dbSNP
rs1353742672 292 dbSNP
rs1176081260 294 dbSNP
rs1461381370 295 dbSNP
rs1448692674 296 dbSNP
rs1186560575 308 dbSNP
rs1244536647 317 dbSNP
rs1246312087 318 dbSNP
rs1448925675 321 dbSNP
rs773756326 325 dbSNP
rs565159494 327 dbSNP
rs1370419586 328 dbSNP
rs1460700224 335 dbSNP
rs373108798 336 dbSNP
rs770879903 337 dbSNP
rs1386092725 338 dbSNP
rs1459329300 339 dbSNP
rs1050373091 342 dbSNP
rs766540255 350 dbSNP
rs1261135889 353 dbSNP
rs932821044 364 dbSNP
rs903633483 366 dbSNP
rs149927302 372 dbSNP
rs375376337 375 dbSNP
rs1217837322 379 dbSNP
rs1261131837 386 dbSNP
rs1352540827 392 dbSNP
rs1206808279 395 dbSNP
rs1043477785 397 dbSNP
rs945043790 398 dbSNP
rs1184301019 399 dbSNP
rs551817716 409 dbSNP
rs144170438 411 dbSNP
rs1383640589 412 dbSNP
rs1187078886 419 dbSNP
rs1317415290 419 dbSNP
rs1364799742 420 dbSNP
rs939246873 426 dbSNP
rs926541309 428 dbSNP
rs1388569039 429 dbSNP
rs1470560240 430 dbSNP
rs1304108729 431 dbSNP
rs1450817292 435 dbSNP
rs1405777074 436 dbSNP
rs184876150 450 dbSNP
rs192537262 451 dbSNP
rs573929050 453 dbSNP
rs386811255 454 dbSNP
rs187634674 455 dbSNP
rs1159035583 458 dbSNP
rs1287420417 459 dbSNP
rs543726728 464 dbSNP
rs1324232921 472 dbSNP
rs1205451669 473 dbSNP
rs1251526010 474 dbSNP
rs1257886790 474 dbSNP
rs1473663976 474 dbSNP
rs1482309882 474 dbSNP
rs35563894 474 dbSNP
rs796287256 474 dbSNP
rs1180503812 476 dbSNP
rs1411634469 486 dbSNP
rs974120933 488 dbSNP
rs1386626767 492 dbSNP
rs569741431 494 dbSNP
rs1015581379 500 dbSNP
rs1465103686 501 dbSNP
rs1008215364 504 dbSNP
rs1372036245 509 dbSNP
rs984522399 513 dbSNP
rs749265123 518 dbSNP
rs80149212 522 dbSNP
rs772988435 526 dbSNP
rs1345891128 527 dbSNP
rs1220934758 538 dbSNP
rs1023894571 541 dbSNP
rs1012164612 556 dbSNP
rs142060546 559 dbSNP
rs571548623 559 dbSNP
rs1232645761 578 dbSNP
rs960943902 579 dbSNP
rs1035016711 585 dbSNP
rs1203243216 596 dbSNP
rs1251605139 598 dbSNP
rs534666453 607 dbSNP
rs1028565799 622 dbSNP
rs1193492307 631 dbSNP
rs1260018766 635 dbSNP
rs1223213474 639 dbSNP
rs1433053994 644 dbSNP
rs997459621 648 dbSNP
rs1170557503 659 dbSNP
rs999550735 663 dbSNP
rs903978897 664 dbSNP
rs1043462636 674 dbSNP
rs902536080 678 dbSNP
rs1366035435 683 dbSNP
rs769638373 692 dbSNP
rs1022361276 694 dbSNP
rs892148935 695 dbSNP
rs1055359 703 dbSNP
rs1298469890 704 dbSNP
rs1340050404 716 dbSNP
rs939013032 722 dbSNP
rs1296561831 728 dbSNP
rs1226537175 729 dbSNP
rs889920696 734 dbSNP
rs1360386334 736 dbSNP
rs1050387625 744 dbSNP
rs934252860 747 dbSNP
rs1366873293 748 dbSNP
rs901448811 760 dbSNP
rs1488457118 761 dbSNP
rs1161077823 764 dbSNP
rs1249413739 769 dbSNP
rs1447126971 778 dbSNP
rs1040019465 781 dbSNP
rs1423486436 782 dbSNP
rs371983685 788 dbSNP
rs1194903038 792 dbSNP
rs1426508482 804 dbSNP
rs781412285 809 dbSNP
rs768778215 817 dbSNP
rs974175733 823 dbSNP
rs907558385 828 dbSNP
rs1322445804 832 dbSNP
rs1367520427 835 dbSNP
rs1260866271 838 dbSNP
rs1200025355 840 dbSNP
rs1296895106 841 dbSNP
rs1490805540 842 dbSNP
rs1266718780 843 dbSNP
rs1288232152 843 dbSNP
rs1015676237 845 dbSNP
rs1321484024 845 dbSNP
rs1270581760 846 dbSNP
rs1355744953 846 dbSNP
rs986831240 847 dbSNP
rs1207585790 854 dbSNP
rs1252095932 855 dbSNP
rs1237515690 856 dbSNP
rs11392622 857 dbSNP
rs1161019415 857 dbSNP
rs1179725109 857 dbSNP
rs1473599657 857 dbSNP
rs1386376225 859 dbSNP
rs1456594632 860 dbSNP
rs1229973512 866 dbSNP
rs1306094362 867 dbSNP
rs750542398 873 dbSNP
rs1028993736 880 dbSNP
rs1378632008 881 dbSNP
rs1229411404 884 dbSNP
rs1290546722 888 dbSNP
rs1327744933 889 dbSNP
rs997072242 894 dbSNP
rs183208867 900 dbSNP
rs533561647 901 dbSNP
rs1301840894 904 dbSNP
rs1022396176 914 dbSNP
rs930435517 922 dbSNP
rs916411976 928 dbSNP
rs991091421 930 dbSNP
rs1169283896 937 dbSNP
rs960638522 942 dbSNP
rs535631582 943 dbSNP
rs1372166461 945 dbSNP
rs569895240 948 dbSNP
rs191079893 955 dbSNP
rs539367999 957 dbSNP
rs1177055046 960 dbSNP
rs1198677016 965 dbSNP
rs966667865 968 dbSNP
rs1022307336 980 dbSNP
rs187295971 982 dbSNP
rs551490520 989 dbSNP
rs548152122 992 dbSNP
rs1028477575 994 dbSNP
rs528535038 995 dbSNP
rs1197750763 1001 dbSNP
rs901356890 1010 dbSNP
rs1228380474 1018 dbSNP
rs1037215697 1022 dbSNP
rs930555718 1031 dbSNP
rs559585722 1032 dbSNP
rs1257702880 1037 dbSNP
rs1426540655 1040 dbSNP
rs1224434586 1041 dbSNP
rs940283335 1048 dbSNP
rs886106546 1055 dbSNP
rs751261580 1056 dbSNP
rs1036227664 1057 dbSNP
rs1048751563 1058 dbSNP
rs1206815316 1060 dbSNP
rs549091598 1061 dbSNP
rs1482604491 1067 dbSNP
rs1199223581 1072 dbSNP
rs183004319 1078 dbSNP
rs916342041 1081 dbSNP
rs758937143 1083 dbSNP
rs751023756 1086 dbSNP
rs1233248283 1088 dbSNP
rs908665080 1096 dbSNP
rs1394530316 1098 dbSNP
rs1430701899 1099 dbSNP
rs563552463 1101 dbSNP
rs1170700934 1104 dbSNP
rs1369163615 1105 dbSNP
rs939153822 1113 dbSNP
rs373409409 1128 dbSNP
rs1409600766 1130 dbSNP
rs927827342 1148 dbSNP
rs1182380503 1156 dbSNP
rs191672288 1165 dbSNP
rs529608384 1168 dbSNP
rs45600540 1176 dbSNP
rs186307355 1177 dbSNP
rs142779879 1180 dbSNP
rs1272050721 1182 dbSNP
rs1470825455 1184 dbSNP
rs1427024432 1185 dbSNP
rs1291712866 1189 dbSNP
rs954134249 1191 dbSNP
rs1449839262 1192 dbSNP
rs1028800602 1201 dbSNP
rs572040017 1202 dbSNP
rs968351069 1203 dbSNP
rs1190513853 1218 dbSNP
rs1388560650 1224 dbSNP
rs1470499449 1232 dbSNP
rs1164230121 1238 dbSNP
rs1393286803 1243 dbSNP
rs1404146027 1244 dbSNP
rs1365490123 1256 dbSNP
rs1325808004 1257 dbSNP
rs34297427 1257 dbSNP
rs576333193 1257 dbSNP
rs62130775 1258 dbSNP
rs998292457 1259 dbSNP
rs1364049569 1260 dbSNP
rs1184034430 1266 dbSNP
rs1022489144 1270 dbSNP
rs1353979674 1273 dbSNP
rs1009730773 1275 dbSNP
rs1268692304 1280 dbSNP
rs1466151805 1281 dbSNP
rs1417407909 1284 dbSNP
rs1210693049 1293 dbSNP
rs956832532 1297 dbSNP
rs1034739565 1299 dbSNP
rs1003266405 1302 dbSNP
rs1204617331 1321 dbSNP
rs904878067 1322 dbSNP
rs1472017890 1323 dbSNP
rs1164587489 1328 dbSNP
rs754285638 1329 dbSNP
rs767149876 1332 dbSNP
rs1261707715 1335 dbSNP
rs115010197 1336 dbSNP
rs1396313071 1340 dbSNP
rs1351973764 1355 dbSNP
rs888730313 1357 dbSNP
rs899117328 1358 dbSNP
rs1048694540 1363 dbSNP
rs1331177761 1368 dbSNP
rs1226462976 1371 dbSNP
rs994888085 1372 dbSNP
rs1236176807 1375 dbSNP
rs1201311698 1378 dbSNP
rs894824482 1380 dbSNP
rs763753201 1393 dbSNP
rs751050935 1400 dbSNP
rs1315303265 1401 dbSNP
rs1055250242 1418 dbSNP
rs535566507 1423 dbSNP
rs1187718866 1424 dbSNP
rs1413124329 1429 dbSNP
rs939118447 1433 dbSNP
rs3143 1436 dbSNP
rs1362786112 1438 dbSNP
rs556402013 1440 dbSNP
rs1466111330 1441 dbSNP
rs1042278098 1444 dbSNP
rs148497448 1451 dbSNP
rs773078301 1452 dbSNP
rs723084 1456 dbSNP
rs1156756987 1479 dbSNP
rs1407983175 1481 dbSNP
rs1306196311 1496 dbSNP
rs1312644243 1497 dbSNP
rs1437891511 1500 dbSNP
rs954152711 1502 dbSNP
rs1234083910 1503 dbSNP
rs1257795646 1508 dbSNP
rs1379838918 1520 dbSNP
rs921281183 1521 dbSNP
rs55636929 1527 dbSNP
rs1446726091 1529 dbSNP
rs1180389120 1530 dbSNP
rs965527397 1532 dbSNP
rs181303741 1533 dbSNP
rs1035128338 1534 dbSNP
rs1177640213 1534 dbSNP
rs982671332 1536 dbSNP
rs1447950214 1544 dbSNP
rs114137642 1552 dbSNP
rs549029931 1553 dbSNP
rs190990186 1554 dbSNP
rs1388416192 1562 dbSNP
rs752513979 1562 dbSNP
rs898790775 1562 dbSNP
rs994549830 1562 dbSNP
rs1014856573 1567 dbSNP
rs1275631727 1574 dbSNP
rs370926049 1576 dbSNP
rs1344520609 1578 dbSNP
rs1004772142 1580 dbSNP
rs890311374 1582 dbSNP
rs1027164692 1587 dbSNP
rs1291928364 1589 dbSNP
rs1247562994 1590 dbSNP
rs1380073039 1592 dbSNP
rs1283241519 1593 dbSNP
rs1051626953 1596 dbSNP
rs1431121728 1597 dbSNP
rs931795196 1598 dbSNP
rs1328042061 1599 dbSNP
rs1316131513 1600 dbSNP
rs1188568457 1601 dbSNP
rs1013175833 1602 dbSNP
rs1419069967 1607 dbSNP
rs1359959128 1608 dbSNP
rs894764887 1609 dbSNP
rs1169534659 1612 dbSNP
rs1426628327 1614 dbSNP
rs1350230521 1618 dbSNP
rs569868945 1624 dbSNP
rs1040153884 1633 dbSNP
rs1393561751 1642 dbSNP
rs1162944226 1646 dbSNP
rs73626610 1647 dbSNP
rs1003695501 1649 dbSNP
rs915215179 1650 dbSNP
rs988371916 1652 dbSNP
rs906309441 1654 dbSNP
rs1295370638 1657 dbSNP
rs1322682072 1681 dbSNP
rs1042226573 1683 dbSNP
rs723082 1686 dbSNP
rs1271831721 1689 dbSNP
rs928194854 1694 dbSNP
rs1208844106 1699 dbSNP
rs1249312349 1700 dbSNP
rs1447337664 1705 dbSNP
rs1488221045 1706 dbSNP
rs915089261 1709 dbSNP
rs1270273137 1711 dbSNP
rs982338782 1712 dbSNP
rs564608759 1714 dbSNP
rs1054076007 1715 dbSNP
rs149376979 1716 dbSNP
rs973525479 1723 dbSNP
rs963052932 1725 dbSNP
rs1428954809 1732 dbSNP
rs1341177015 1745 dbSNP
rs921257854 1756 dbSNP
rs976809858 1765 dbSNP
rs1558355 1768 dbSNP
rs908612063 1771 dbSNP
rs757507442 1779 dbSNP
rs1291776557 1781 dbSNP
rs890405941 1819 dbSNP
rs952849251 1826 dbSNP
rs527266492 1827 dbSNP
rs1027114223 1828 dbSNP
rs1406828948 1839 dbSNP
rs992150503 1844 dbSNP
rs996063363 1855 dbSNP
rs1484003527 1856 dbSNP
rs773857198 1860 dbSNP
rs1472903645 1861 dbSNP
rs8103783 1861 dbSNP
rs541907100 1864 dbSNP
rs1414364015 1866 dbSNP
rs1477702566 1873 dbSNP
rs1158403379 1880 dbSNP
rs1359989096 1889 dbSNP
rs1039803638 1890 dbSNP
rs946779936 1897 dbSNP
rs1355211797 1898 dbSNP
rs1411049893 1899 dbSNP
rs1290762360 1906 dbSNP
rs1349096180 1908 dbSNP
rs1222732423 1909 dbSNP
rs1295500496 1924 dbSNP
rs1003233655 1934 dbSNP
rs906216540 1941 dbSNP
rs745946445 1947 dbSNP
rs1256610738 1948 dbSNP
rs935328465 1950 dbSNP
rs1183994751 1951 dbSNP
rs1202300185 1952 dbSNP
rs1469521196 1954 dbSNP
rs1487217201 1980 dbSNP
rs1425932737 1985 dbSNP
rs1245667194 1986 dbSNP
rs576211258 1989 dbSNP
rs186131600 2007 dbSNP
rs1439146590 2008 dbSNP
rs545673608 2011 dbSNP
rs1430822840 2014 dbSNP
rs1310188921 2016 dbSNP
rs893602498 2021 dbSNP
rs1442068394 2026 dbSNP
rs4801386 2027 dbSNP
rs1217725698 2031 dbSNP
rs1324071666 2032 dbSNP
rs1279164616 2038 dbSNP
rs1342360972 2039 dbSNP
rs1207062016 2043 dbSNP
rs1270573236 2047 dbSNP
rs1437217585 2051 dbSNP
rs553752940 2055 dbSNP
rs1221650472 2063 dbSNP
rs534107764 2066 dbSNP
rs1455646026 2082 dbSNP
rs1191764064 2094 dbSNP
rs899774102 2097 dbSNP
rs973166072 2100 dbSNP
rs1450285293 2102 dbSNP
rs1292964724 2104 dbSNP
rs1443061236 2112 dbSNP
rs1356428429 2113 dbSNP
rs1041380382 2119 dbSNP
rs963146405 2120 dbSNP
rs1438092073 2125 dbSNP
rs944015664 2131 dbSNP
rs907611421 2133 dbSNP
rs1365513178 2139 dbSNP
rs1230132012 2145 dbSNP
rs983149038 2146 dbSNP
rs908557950 2155 dbSNP
rs1338502597 2159 dbSNP
rs181845486 2161 dbSNP
rs1030256740 2166 dbSNP
rs374631594 2166 dbSNP
rs574029043 2166 dbSNP
rs1211940136 2173 dbSNP
rs1465421733 2175 dbSNP
rs996467880 2183 dbSNP
rs982791417 2193 dbSNP
rs12980845 2194 dbSNP
rs1465549898 2197 dbSNP
rs964595278 2218 dbSNP
rs765218502 2224 dbSNP
rs1432000507 2228 dbSNP
rs1425112621 2235 dbSNP
rs931437470 2237 dbSNP
rs920082175 2241 dbSNP
rs991700611 2242 dbSNP
rs796914535 2243 dbSNP
rs78174116 2247 dbSNP
rs1035923243 2249 dbSNP
rs1011352891 2252 dbSNP
rs1264823185 2256 dbSNP
rs982111692 2260 dbSNP
rs1383630163 2267 dbSNP
rs1052472280 2285 dbSNP
rs1311493925 2286 dbSNP
rs970345229 2287 dbSNP
rs11666110 2288 dbSNP
rs1009316236 2291 dbSNP
rs1375693687 2292 dbSNP
rs893590878 2294 dbSNP
rs1272691805 2301 dbSNP
rs1465401346 2301 dbSNP
rs1206908054 2306 dbSNP
rs906491635 2311 dbSNP
rs1446592648 2325 dbSNP
rs1383963486 2328 dbSNP
rs1046654030 2329 dbSNP
rs1032573450 2331 dbSNP
rs1339053611 2334 dbSNP
rs754198858 2336 dbSNP
rs899680417 2340 dbSNP
rs569805695 2341 dbSNP
rs1474546382 2343 dbSNP
rs778047889 2348 dbSNP
rs943961653 2356 dbSNP
rs1454904278 2362 dbSNP
rs146733496 2364 dbSNP
rs1401930048 2375 dbSNP
rs1377989644 2376 dbSNP
rs1396217148 2386 dbSNP
rs1314541043 2395 dbSNP
rs748632223 2398 dbSNP
rs1353321222 2402 dbSNP
rs1414167878 2408 dbSNP
rs1288919173 2409 dbSNP
rs1037901776 2416 dbSNP
rs144123248 2416 dbSNP
rs571048482 2424 dbSNP
rs371223004 2426 dbSNP
rs751235428 2433 dbSNP
rs1201226685 2440 dbSNP
rs1282995982 2453 dbSNP
rs1484897572 2455 dbSNP
rs1187606345 2457 dbSNP
rs920045936 2463 dbSNP
rs1421354646 2464 dbSNP
rs1155461 2469 dbSNP
rs1179833794 2489 dbSNP
rs1482812209 2497 dbSNP
rs1466280274 2498 dbSNP
rs922906543 2533 dbSNP
rs200173182 2536 dbSNP
rs376017612 2538 dbSNP
rs937496442 2541 dbSNP
rs1217949032 2544 dbSNP
rs1355912079 2553 dbSNP
rs766056225 2558 dbSNP
rs528000961 2562 dbSNP
rs1308359181 2576 dbSNP
rs1375487212 2576 dbSNP
rs1389574579 2582 dbSNP
rs1305021394 2586 dbSNP
rs1335240674 2588 dbSNP
rs1021490733 2591 dbSNP
rs1282754419 2593 dbSNP
rs1210652170 2594 dbSNP
rs1275754901 2596 dbSNP
rs1481933077 2598 dbSNP
rs1299538233 2599 dbSNP
rs1194567617 2602 dbSNP
rs1239548161 2604 dbSNP
rs1011405159 2606 dbSNP
rs981649524 2607 dbSNP
rs34172934 2608 dbSNP
rs398038497 2608 dbSNP
rs967660184 2609 dbSNP
rs1317439101 2614 dbSNP
rs561621956 2615 dbSNP
rs1046853876 2619 dbSNP
rs987831390 2619 dbSNP
rs1012235138 2622 dbSNP
rs1353777531 2624 dbSNP
rs1433557103 2628 dbSNP
rs1305669819 2633 dbSNP
rs1359207103 2637 dbSNP
rs1157485875 2642 dbSNP
rs957962327 2650 dbSNP
rs542201329 2653 dbSNP
rs541846048 2656 dbSNP
rs1489066893 2659 dbSNP
rs1037955611 2667 dbSNP
rs1250564597 2669 dbSNP
rs997010751 2671 dbSNP
rs1162331214 2677 dbSNP
rs1421477229 2683 dbSNP
rs1462987252 2696 dbSNP
rs908014051 2699 dbSNP
rs1047530679 2706 dbSNP
rs1462918035 2719 dbSNP
rs963873137 2721 dbSNP
rs1392355184 2722 dbSNP
rs1262220407 2728 dbSNP
rs879616111 2739 dbSNP
rs1487241642 2740 dbSNP
rs749954743 2743 dbSNP
rs1215906152 2747 dbSNP
rs1019905817 2751 dbSNP
rs923033513 2755 dbSNP
rs974850631 2757 dbSNP
rs1336165142 2758 dbSNP
rs1235659029 2761 dbSNP
rs1270789163 2767 dbSNP
rs1215809911 2768 dbSNP
rs368589574 2769 dbSNP
rs1243510834 2770 dbSNP
rs1242928259 2775 dbSNP
rs1008091931 2784 dbSNP
rs1484665464 2784 dbSNP
rs887055685 2786 dbSNP
rs28648863 2789 dbSNP
rs1256566422 2794 dbSNP
rs1296673381 2810 dbSNP
rs1415623542 2812 dbSNP
rs914495664 2824 dbSNP
rs1416986202 2827 dbSNP
rs995443051 2831 dbSNP
rs1461002671 2833 dbSNP
rs570232941 2838 dbSNP
rs1298136381 2841 dbSNP
rs955883353 2844 dbSNP
rs562556780 2845 dbSNP
rs1356491898 2857 dbSNP
rs1291400457 2859 dbSNP
rs138560597 2866 dbSNP
rs1291985485 2867 dbSNP
rs1055846889 2878 dbSNP
rs937423099 2885 dbSNP
rs928815225 2888 dbSNP
rs1457139020 2901 dbSNP
rs1373315749 2902 dbSNP
rs1172221593 2907 dbSNP
rs1285710577 2911 dbSNP
rs1314812100 2912 dbSNP
rs545904180 2916 dbSNP
rs1476722651 2917 dbSNP
rs761792117 2918 dbSNP
rs776476844 2925 dbSNP
rs77039306 2926 dbSNP
rs1200136069 2935 dbSNP
rs1025049986 2937 dbSNP
rs1410224671 2939 dbSNP
rs990415419 2939 dbSNP
rs1269616845 2943 dbSNP
rs957696108 2946 dbSNP
rs924944029 2953 dbSNP
rs1376220844 2955 dbSNP
rs758696018 2974 dbSNP
rs189588919 2978 dbSNP
rs964169942 2985 dbSNP
rs895107632 2991 dbSNP
rs1252113680 2993 dbSNP
rs1019394075 2997 dbSNP
rs775519479 3000 dbSNP
rs1008037878 3008 dbSNP
rs772447008 3033 dbSNP
rs540105144 3037 dbSNP
rs1370530648 3056 dbSNP
rs886673557 3059 dbSNP
rs1278118978 3067 dbSNP
rs574387708 3072 dbSNP
rs1047954169 3079 dbSNP
rs933497198 3080 dbSNP
rs901630265 3083 dbSNP
rs750736776 3085 dbSNP
rs1298498739 3101 dbSNP
rs1385766233 3108 dbSNP
rs1438377288 3112 dbSNP
rs1206522472 3115 dbSNP
rs1396689787 3115 dbSNP
rs554482612 3124 dbSNP
rs1468671466 3127 dbSNP
rs1056236026 3147 dbSNP
rs1395953498 3161 dbSNP
rs1455721507 3164 dbSNP
rs1038743534 3168 dbSNP
rs1375204945 3170 dbSNP
rs1411080184 3171 dbSNP
rs1399319595 3174 dbSNP
rs1177036920 3177 dbSNP
rs1474930067 3181 dbSNP
rs745903670 3187 dbSNP
rs907308151 3192 dbSNP
rs1375885464 3196 dbSNP
rs796319011 3199 dbSNP
rs774612372 3202 dbSNP
rs1372777352 3206 dbSNP
rs1231601240 3208 dbSNP
rs946170466 3210 dbSNP
rs913412120 3221 dbSNP
rs576297440 3230 dbSNP
rs936292364 3231 dbSNP
rs924516084 3233 dbSNP
rs1270815482 3252 dbSNP
rs981715618 3254 dbSNP
rs924966639 3266 dbSNP
rs1198133097 3271 dbSNP
rs975515288 3273 dbSNP
rs971251595 3285 dbSNP
rs1204736491 3288 dbSNP
rs942447814 3292 dbSNP
rs771542353 3293 dbSNP
rs1169955977 3301 dbSNP
rs73626608 3305 dbSNP
rs959379065 3307 dbSNP
rs951181607 3313 dbSNP
rs1396021491 3318 dbSNP
rs1438346407 3319 dbSNP
rs1231820452 3320 dbSNP
rs1025434941 3330 dbSNP
rs974014350 3337 dbSNP
rs1006214295 3346 dbSNP
rs1338722019 3353 dbSNP
rs1233808150 3372 dbSNP
rs1273959988 3375 dbSNP
rs886726086 3381 dbSNP
rs1026566321 3384 dbSNP
rs1266964099 3385 dbSNP
rs1447761857 3386 dbSNP
rs375125357 3398 dbSNP
rs778193721 3405 dbSNP
rs10407687 3406 dbSNP
rs377138818 3415 dbSNP
rs556380335 3424 dbSNP
rs184965266 3425 dbSNP
rs907217164 3426 dbSNP
rs1221483920 3434 dbSNP
rs1024362882 3446 dbSNP
rs1010328225 3450 dbSNP
rs1162075774 3457 dbSNP
rs1385272087 3458 dbSNP
rs1402062180 3462 dbSNP
rs1007284111 3471 dbSNP
rs1339588304 3479 dbSNP
rs892868123 3482 dbSNP
rs891969299 3485 dbSNP
rs1399902410 3486 dbSNP
rs1353431041 3488 dbSNP
rs1054666025 3490 dbSNP
rs1231563062 3490 dbSNP
rs924569702 3492 dbSNP
rs1171983423 3499 dbSNP
rs936255437 3507 dbSNP
rs1045612098 3510 dbSNP
rs949931157 3523 dbSNP
rs915716886 3525 dbSNP
rs866874557 3534 dbSNP
rs1465603305 3538 dbSNP
rs74582744 3541 dbSNP
rs1364499836 3542 dbSNP
rs900775295 3544 dbSNP
rs1186287818 3547 dbSNP
rs75588968 3548 dbSNP
rs1180723817 3549 dbSNP
rs1156449199 3550 dbSNP
rs991714014 3556 dbSNP
rs1435126344 3558 dbSNP
rs942329674 3559 dbSNP
rs912235282 3561 dbSNP
rs1237838054 3562 dbSNP
rs1184525564 3570 dbSNP
rs202223891 3582 dbSNP
rs909289496 3584 dbSNP
rs1241192014 3594 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions islets
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO. ...

- Kameswaran V; Bramswig NC; McKenna LB; Penn et al., 2014, Cell metabolism.

Article - Kameswaran V; Bramswig NC; McKenna LB; Penn et al.
- Cell metabolism, 2014
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing beta cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the pathogenesis of human T2DM, we sequenced the small RNAs of human islets from diabetic and nondiabetic organ donors. We identified a cluster of microRNAs in an imprinted locus on human chromosome 14q32 that is highly and specifically expressed in human beta cells and dramatically downregulated in islets from T2DM organ donors. The downregulation of this locus strongly correlates with hypermethylation of its promoter. Using HITS-CLIP for the essential RISC-component Argonaute, we identified disease-relevant targets of the chromosome 14q32 microRNAs, such as IAPP and TP53INP1, that cause increased beta cell apoptosis upon overexpression in human islets. Our results support a role for microRNAs and their epigenetic control by DNA methylation in the pathogenesis of T2DM.
LinkOut: [PMID: 24374217]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
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138 hsa-miR-412-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT005780 ACVR1C activin A receptor type 1C 1 1
MIRT062013 YOD1 YOD1 deubiquitinase 2 2
MIRT345112 ATXN7L3 ataxin 7 like 3 2 2
MIRT383735 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT396956 CELF1 CUGBP Elav-like family member 1 2 2
MIRT439280 XIAP X-linked inhibitor of apoptosis 1 1
MIRT439313 VAT1 vesicle amine transport 1 1 1
MIRT439375 TUBA1A tubulin alpha 1a 1 1
MIRT439418 TMOD1 tropomodulin 1 1 1
MIRT439503 SURF4 surfeit 4 1 1
MIRT439563 SON SON DNA binding protein 1 1
MIRT439598 SLC3A2 solute carrier family 3 member 2 1 1
MIRT439670 SETD1B SET domain containing 1B 1 1
MIRT439767 RMND5A required for meiotic nuclear division 5 homolog A 1 1
MIRT439922 PPL periplakin 1 1
MIRT439947 PLEKHA6 pleckstrin homology domain containing A6 1 1
MIRT439952 PLCB4 phospholipase C beta 4 1 1
MIRT439961 PKD1 polycystin 1, transient receptor potential channel interacting 1 1
MIRT440005 PEG3 paternally expressed 3 1 1
MIRT440061 OSBPL8 oxysterol binding protein like 8 1 1
MIRT440166 MYH14 myosin heavy chain 14 1 1
MIRT440276 MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1 1
MIRT440437 IPO13 importin 13 1 1
MIRT440441 INTS3 integrator complex subunit 3 1 1
MIRT440448 INS insulin 1 1
MIRT440461 IGF2R insulin like growth factor 2 receptor 1 1
MIRT440472 IARS isoleucyl-tRNA synthetase 1 1
MIRT440530 GUCY1A3 guanylate cyclase 1 soluble subunit alpha 1 1
MIRT440542 GOLGA2 golgin A2 1 1
MIRT440569 GIGYF1 GRB10 interacting GYF protein 1 1 1
MIRT440608 FTSJD2 cap methyltransferase 1 1 1
MIRT440750 EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1 1
MIRT440781 DOT1L DOT1 like histone lysine methyltransferase 1 1
MIRT440804 DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 1 1
MIRT440867 CSDE1 cold shock domain containing E1 1 1
MIRT440890 CPEB4 cytoplasmic polyadenylation element binding protein 4 1 1
MIRT440917 COL1A1 collagen type I alpha 1 chain 1 1
MIRT440967 CDH22 cadherin 22 1 1
MIRT440968 CDH2 cadherin 2 1 1
MIRT441024 CALR calreticulin 1 1
MIRT441278 ACTB actin beta 1 1
MIRT448421 TNFAIP3 TNF alpha induced protein 3 2 2
MIRT462833 BCL3 B-cell CLL/lymphoma 3 2 2
MIRT465062 TSR1 TSR1, ribosome maturation factor 2 2
MIRT476050 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT485318 MZT1 mitotic spindle organizing protein 1 2 4
MIRT493584 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 6
MIRT494567 BAK1 BCL2 antagonist/killer 1 2 2
MIRT497393 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT503250 ZNF257 zinc finger protein 257 2 10
MIRT503656 ZNF138 zinc finger protein 138 2 10
MIRT505882 RNF219 ring finger protein 219 2 2
MIRT507525 DSTN destrin, actin depolymerizing factor 2 4
MIRT510663 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 4
MIRT514682 ZNF701 zinc finger protein 701 2 4
MIRT515370 ZNF208 zinc finger protein 208 2 6
MIRT525237 KCNJ12 potassium voltage-gated channel subfamily J member 12 2 2
MIRT527963 MTAP methylthioadenosine phosphorylase 2 2
MIRT528482 STAMBPL1 STAM binding protein like 1 2 2
MIRT529909 C1orf64 steroid receptor associated and regulated protein 2 4
MIRT531558 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT532234 KLF2 Kruppel like factor 2 2 4
MIRT532480 HOXA13 homeobox A13 2 2
MIRT535544 P2RY2 purinergic receptor P2Y2 2 2
MIRT547311 NR1D2 nuclear receptor subfamily 1 group D member 2 2 2
MIRT551795 ZNF117 zinc finger protein 117 2 4
MIRT554939 RAP1A RAP1A, member of RAS oncogene family 2 2
MIRT558171 EIF5A2 eukaryotic translation initiation factor 5A2 2 2
MIRT568771 LY6K lymphocyte antigen 6 family member K 2 2
MIRT570766 ZNF99 zinc finger protein 99 2 2
MIRT572405 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT573396 DLC1 DLC1 Rho GTPase activating protein 2 2
MIRT610403 RXRB retinoid X receptor beta 2 2
MIRT610886 SCN8A sodium voltage-gated channel alpha subunit 8 2 2
MIRT611197 TMEM105 transmembrane protein 105 2 2
MIRT611244 ZNF550 zinc finger protein 550 2 2
MIRT615669 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 4
MIRT617974 DOCK4 dedicator of cytokinesis 4 2 2
MIRT619150 ZNF326 zinc finger protein 326 2 2
MIRT619608 MKKS McKusick-Kaufman syndrome 2 2
MIRT621053 DGKD diacylglycerol kinase delta 2 2
MIRT623665 HRK harakiri, BCL2 interacting protein 2 2
MIRT624883 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT624939 MARCH2 membrane associated ring-CH-type finger 2 2 2
MIRT634198 TMOD2 tropomodulin 2 2 4
MIRT636727 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT637741 POLR3K RNA polymerase III subunit K 2 2
MIRT638002 ZC3H13 zinc finger CCCH-type containing 13 2 2
MIRT640395 ZNF785 zinc finger protein 785 2 2
MIRT640505 ANTXR1 anthrax toxin receptor 1 2 2
MIRT641293 SLAMF1 signaling lymphocytic activation molecule family member 1 2 2
MIRT641863 STOML1 stomatin like 1 2 2
MIRT642600 C14orf180 chromosome 14 open reading frame 180 2 2
MIRT642895 CASP1 caspase 1 2 2
MIRT643967 FHL2 four and a half LIM domains 2 2 4
MIRT645237 KCTD12 potassium channel tetramerization domain containing 12 2 2
MIRT646621 CENPL centromere protein L 2 2
MIRT648620 CYB561A3 cytochrome b561 family member A3 2 2
MIRT648908 ZNF551 zinc finger protein 551 2 2
MIRT649439 HIBADH 3-hydroxyisobutyrate dehydrogenase 2 2
MIRT650637 LTF lactotransferrin 2 2
MIRT650971 STARD3NL STARD3 N-terminal like 2 2
MIRT651067 ZNF518B zinc finger protein 518B 2 4
MIRT652384 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT653958 SEPN1 selenoprotein N 2 2
MIRT656885 KIF1C kinesin family member 1C 2 2
MIRT657965 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT658080 FOXR2 forkhead box R2 2 2
MIRT662570 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT663089 METTL10 EEF1A lysine methyltransferase 2 2 2
MIRT683705 ZNF195 zinc finger protein 195 2 2
MIRT683835 ZNF682 zinc finger protein 682 2 2
MIRT706811 APOL4 apolipoprotein L4 2 2
MIRT707575 DYNC2LI1 dynein cytoplasmic 2 light intermediate chain 1 2 2
MIRT708606 ZNF260 zinc finger protein 260 2 2
MIRT708859 TMSB4X thymosin beta 4, X-linked 2 2
MIRT709861 PDIK1L PDLIM1 interacting kinase 1 like 2 2
MIRT709987 RBM41 RNA binding motif protein 41 2 2
MIRT710098 KPNA5 karyopherin subunit alpha 5 2 2
MIRT710211 ENAH ENAH, actin regulator 2 2
MIRT710868 B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2 2
MIRT710986 SUSD5 sushi domain containing 5 2 2
MIRT711460 RNF145 ring finger protein 145 2 2
MIRT712302 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT713609 SYTL4 synaptotagmin like 4 2 2
MIRT713789 MAK16 MAK16 homolog 2 2
MIRT715480 MYO9B myosin IXB 2 2
MIRT716328 POU5F1 POU class 5 homeobox 1 2 2
MIRT717252 TMEM246 transmembrane protein 246 2 2
MIRT718077 CLIC5 chloride intracellular channel 5 2 2
MIRT718463 EED embryonic ectoderm development 2 2
MIRT718645 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT718982 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT721078 RPS9 ribosomal protein S9 2 2
MIRT721419 SEC24A SEC24 homolog A, COPII coat complex component 2 2
MIRT721863 CENPJ centromere protein J 2 2
MIRT722492 PNKD paroxysmal nonkinesigenic dyskinesia 2 2
MIRT723391 CALN1 calneuron 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-412 Gemcitabine approved 60750 Northern blot Mz-ChA-1 human cholangiocarcinoma cell lines 16762633 2006 down-regulated
miR-412 Progesterone approved 5994 Microarray Breast cancer 22330642 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-412 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-412 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-412-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-412-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-miR-412-3p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (RKO)
hsa-miR-412-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HCT-116)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-miR-412-3p Doxorubicin 31703 NSC123127 approved sensitive High Anaplastic Thyroid Cancer tissue
hsa-miR-412-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-412-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-412-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM43)
hsa-miR-412-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-412-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-412-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (Panc1-GR1)
hsa-miR-412-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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