miRTarBase - #MIRT440029


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pre-miRNA Information
pre-miRNA hsa-mir-127   
Genomic Coordinates chr14: 100882979 - 100883075
Description Homo sapiens miR-127 stem-loop
Comment This miRNA sequence is predicted based on homology to a verified miRNA from mouse .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-127-5p
Sequence 23| CUGAAGCUCAGAGGGCUCUGAU |44
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM9722115 13 COSMIC
COSM7115045 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs867796380 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PCLO   
Synonyms ACZ, PCH3
Description piccolo presynaptic cytomatrix protein
Transcript NM_033026   
Other Transcripts NM_014510   
Expression
Putative miRNA Targets on PCLO
3'UTR of PCLO
(miRNA target sites are highlighted)		 
>PCLO|NM_033026|3'UTR
   1 AGAAACATGTCTTCTCAGGGTATAGAAACTGCTCTAAATAGCCTCACATCAAGACTATAGTTGAATACTATTGTACAAAG
  81 CTAAGTTTTGAGAGGCAAACATAAGAGTGGGAACAACAAGCAAAAACATACTTAAGACCTTGTACATTTATTGTTGTGGA
 161 TCACACAAAGATATTCAACTGAAAAAGTTCACATACTGAAAACAAGAAGAATGGAGTTCTGAGACCTTGAATTTCCCATG
 241 GCTGTGAAGAGAAACTGTGAAACAAATTTTGATTACTTAAGACAATAATCTTTGAGTAGAGTTGAGCTATAGCTTAAGAC
 321 AGGCTCAAAGATTAATGTGGTTTTCATGCAGCACAAAGGTAATTCTTTATGCAAAGGAGCCTTGGTTGAAAGGAAAGGAC
 401 TGATGTAACAAATCTCAGTTTTCAAAACTTCAAAAATCTTCCTTCATCGTCTTCTATTCAGACAACTTGCTGCTTTCAGA
 481 TTCTGACATAAGATATACCTACAGTATGTGTCCAGGGCTGGAAGTGAGGTGGCTGTGTTCTTAGGGAAAATGGAAGAGGA
 561 GATGTAGAAATTGTGGCTTTCAGGCCATATTTTACCAGTTTTCTCTGTGTCTAAATGTTACAAGCATATACAACACTGAC
 641 TTTGGAATCCATGTGGTAAAAGCACATTTGTTTCTGTATCATTTGAAACAAGGTAGAGTGAAGATAATACTCAGTAGAAA
 721 TAAAATTGAATTTATCTAGAAATAAAACTATGACTGGCTAACAAAGAAGAATGTTGCCCCATAAAATATTGGAATTTTGG
 801 TTGAAACCATCAAAATCTTCATAATTTACCATTAAGCCAAGACATCTTCAGTCTATGTACCAAAGGACCTAGAGTAAACT
 881 GATATGTTCTAGGAAGCATGATAACTTACTCTTTGTGAAACTGCAAATAAATGTATTATCCTGCACATTTCCTTTCTGTT
 961 GAGCGATGCATTGACAGAGAAAGAAAATTCTTTCTCTGGCAAACAAACCATATTAATCTTGTGACATTGATTAATTAAAT
1041 GGATCCTCATTTCATAATATTTTATGCTTTTTTCCTTAATGACTTAATTCATTTACTGATTGTATCATGAAAACATGACA
1121 CTAAACTCGAGTTCTCTCTAGTGCTCTATTTTCTTACTTTAGTGACAGTATCACAGTGATCAAGTTCATCAATGTTGGGA
1201 AAATATGTGAAAAGTCAACATTTACCTGAGATTAAAATATACTTTGAGCTATTTTAATAATAATGAATAAAACAACTAAT
1281 GTCCAAGTCTTAAAATGAAGCACCCTCTTCTCTATCAGCATTATTAATTAAGGAAGTAACGTGAAGTTGTGGAAAAAACA
1361 CTCAGCAGGGAATAAAAGCCTGTCTTCTGGTCTTAGTTCTACCACTGACTGTGTCACTTTGCACATGTCACTTACACTCA
1441 CTTTACCCCAGTTTTCTTATCTATAGGATAAAAACAATTATATATTCTTAACCTTCCAAATGAGATGTTGTGATGATAAA
1521 TCAATGATCCATGAAAGATGAAAGCACATTTCCAAATATAGTTTTATACACAGAAGTGAGGAATAATTATTACATATCTT
1601 TTTAATTCTCAAATTTTATATGTGAAAAACATCATCTAAACCAATGGCAAGGATTGACATGGATAAAAGCAGTAAATTAG
1681 CCACAAAACTTATTTTTTATTTAAAATATAAACTTTAACCTGACTAAAGGTGAAGAATTACATGAAAATGCAAATTTTGC
1761 TATCCCAAATTAAATGAATAATGCTGGTCTTACCCTAGTCCTATATTCCACCCAAAAGAAATAAATCAAATTGCTTCTCA
1841 GAGCATTCTGAGCTTAAAACCTGCTGCTTTATTTAAGGGTGAAGTGTTAGTGGAATTAGAGAAAACCAACTCTAGATATT
1921 GGTTGGATATTGAATTTTCTCATTTTTAAAGAAAAAATGCTCTAAATTTGAGAGGACTGTAAAGCACTAAAAATAAGAGA
2001 ATTTCTAATATATCCCAGGATATATATATATATATATGACTTCAGAATACAAATTCGATCTTCCCCAAACTGAGAAAGAT
2081 AACCATAACTTTTCTTCCCTCTATTTTTTAATCCCCCTCCACTGACAATACAATGTCATTTACCATTGACATTGCTCTCA
2161 AATGAGCATGGGAGAGTGGAATCATCAAAGACATTATATTGCTAGTATTTTATTTTTAGAAACTATTAGATCTGCTGATG
2241 GTTGCCATGGATATTTCCAGCAGAAGCTAGCACTTGAAGAAGCCTATAATCATCACTCATAATTGGGGAAGAAAAGGTCC
2321 AAGGAGATCTCCTTCTGACATAAAAAGGCTCTGGTATTTGCCCTTAAAAGAAAACCCTGACTCATCTCTGATCCTCTTTT
2401 GCAGCCACTCATATCCATAGGTATGCATGAGAGTTTGTATGACCAGTTAGCTTTCTTCATTCCAGTTGCAATTTCTTTTA
2481 GAATAATATAAATGGAGGGATCACCAAAACAAAGATTATCTCTTTGGTAGCTATTTAACCTGAAAGCGTAGGAGTCTTTC
2561 CATTATAGAAGCCCCTCCGTTCCAAGGAACTAGCGATGGGGCTAGGTCAATCAGCAGAGTTGACAACAGGGCTTCTTTTT
2641 GTGCACCAGCATTCCCCTTCAGAGAGCATAAGATCCTGCCAGTGTGCCAAGTTTGCAGCTGACCAAACTTCTAGGTTGTA
2721 CTGGAATTATTCTATGCAACACTGATCCTTATATGAATGCGTTTCTTCTGAATGATGTTGACTACCCTTCTTACAACAAA
2801 ACTGTTTCTTTTTTATTGCAAATAGGGCTCTTGGTGTTTTTTACTTTTTTGTACATATCACAGTACATGGTTTTTCACTC
2881 TTTAGTTTATTTCATTTTATTGGAATTAACTTTTTTTTATTCTAATACTGACAGAGTTTGTAATCTCTATATAATACGTA
2961 ATTACTCCAATTACAGCACTTTTACCTTGAAGAGCATCTCAGTTTTTCCCACAATTTCATTGAGTCATCAGAGACTGATG
3041 TTGCTTCTTGGTTTCAAATTTGGTCCTAAAGAAACTTTCGGCTGTAGAAACAAAAGCACAGAGTGAATTTTTTACAAAAG
3121 ACAGGGAATATAGAATAGTCATTACAGACACAAATAACCCTAGTAGCACGAAGTTGGTGTTTTCTCTGTTTTTACTTAAG
3201 ATTAAGAAGATTTTTGGTGACTCTGAACTCTTTATTTATATTTCAGTTTAAAATATCAAGACTAAGGGGCATCAGTTATC
3281 TTTACTCTTTAATATTGCCCATATTTTAATAAATTACACTAATTAAACGCATATTTTCAGCATACCAGTGGAATTAATTT
3361 TGTGGATCACACACATTTAAATAGTCATATTGTGGGAATATTATAGCTGGTAACCAGCTGATATTGATTCTTATTATAGG
3441 AATGACTGTAATGATAGTGGTGGTAGCAGTAGTGATATTAGCGGTGGTGGTGATGTGAAGTAAAATAAAAGTATATATTA
3521 TATTGTGCCCAATTTATTAGAAATTATTTGATCAATGCTTCATTTCATTAAAATATCATAAAGATGTTTATAGTATTTTT
3601 TTACTTTATTATTTAAATCATAACTAACAATATTTTTAAAAACTTATTTTCATTGCTACAATGTCAAATATTCCAAAATC
3681 AGCCAACTACAGCTATATATGTGTTATGTGTGACAGAAGTGATCTTCCTTCCCTCTTTTTGAGCTTGACATGAAAGTGAA
3761 AGAAGACTCAATGAATAATTATGAGCTATTTATTTAATAATTACTTGCCTTGGGTGTAATACAGTAATGAATGAGTGAAA
3841 CAAATATTCTCATTGAATATGATACAATGCTGTTTTCTGTATGTTTCATGTTCTATTATTAAAGGTATCCATTAGGCCAA
3921 AATTATTTAATCAAATTCTTTATCTGATAGGTAGATTGAGAGCATTTTCTTAATGCATTACCTTGTACATAAGTATACAC
4001 TTGGTAAAGTAGACGAAGTTGAAATATTAATTTCATTTGGCATTTAGCATGTGAATATGATTATTGTTTGATTGTGTCTG
4081 TATATTTGTTTGGTGACGTGCTCAGGTGCTCCCACTACTGATTAATGTGTGTGCTAATATCCTAAAAACACATATGAGGT
4161 TTAAGAAAAAATTTTCTTGTCTGAAAACATAAACATCTTAATAAAACTGATTTTGAAATAAAAACTAAAGTACTTGAAGA
4241 TATGTCTTGTTTCTAACTATATGTTGCATGCCATGTTGGTGATTTGCTAATGTGTTTTTTTGTTTGTTTGTTTTACCCAA
4321 ATCCCTTTGGAAAATCTAATGGACAAATGCAAATTCTTGGACTAAGGACTGTATAAATTGACCTGAAAATACATGAGAGT
4401 TGCATTTAAAAAAAAATGCTTGTAAATCCGTCTTGAGTTTTACTCTATGTAAAAATATGTCTTGGTTTTGTGATTGTATA
4481 CAAGATGTATCTTGATAACTTATGTAAACTGTGCCGTATAAAGGCTGTTGCCTCAGCCTTACTAATAAATACTGAAAATA
4561 TCACCTTTGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaGUCUCGGGAGACUCGAAGUc 5'
            |||||| :||||||||| | 
Target 5' ctCAGAGCATTCTGAGCTTAAa 3'
 1837 - 1858 156.00 -25.52
2 
miRNA  3' uaGUCUCGGGAG-ACUCGAAGUc 5'
            :| | || || ||||:||:| 
Target 5' tgTAAATCCGTCTTGAGTTTTAc 3'
 4421 - 4443 132.00 -12.50
3 
miRNA  3' uagucucGGGAGACUCGAAGUc 5'
                 |::|:||||||| | 
Target 5' cttccctCTTTTTGAGCTTGAc 3'
 3728 - 3749 131.00 -15.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN509962 1 COSMIC
COSN15625765 2 COSMIC
COSN26988231 9 COSMIC
COSN26988229 11 COSMIC
COSN19669405 21 COSMIC
COSN31483228 25 COSMIC
COSN26988230 26 COSMIC
COSN30164459 34 COSMIC
COSN30181824 41 COSMIC
COSN30186366 47 COSMIC
COSN31609197 53 COSMIC
COSN21635421 66 COSMIC
COSN30187617 70 COSMIC
COSN30524519 76 COSMIC
COSN30495248 84 COSMIC
COSN26988232 85 COSMIC
COSN30103515 86 COSMIC
COSN30479315 87 COSMIC
COSN30528210 94 COSMIC
COSN30189543 95 COSMIC
COSN30187551 96 COSMIC
COSN1354356 116 COSMIC
COSN18719491 120 COSMIC
COSN30100499 128 COSMIC
COSN30102676 131 COSMIC
COSN30169459 138 COSMIC
COSN8517755 145 COSMIC
COSN2237770 153 COSMIC
COSN30181921 155 COSMIC
COSN30461041 170 COSMIC
COSN509961 186 COSMIC
COSN30475906 213 COSMIC
COSN30469628 229 COSMIC
COSN30115333 290 COSMIC
COSN27354764 349 COSMIC
COSN8572228 382 COSMIC
COSN6517160 428 COSMIC
COSN23158223 459 COSMIC
COSN6894088 465 COSMIC
COSN28834702 466 COSMIC
COSN4872484 500 COSMIC
COSN5664160 506 COSMIC
COSN20091631 757 COSMIC
COSN25276571 1027 COSMIC
COSN8572227 1055 COSMIC
COSN16821782 1098 COSMIC
COSN2237769 1115 COSMIC
COSN25429248 1338 COSMIC
COSN9772197 1375 COSMIC
COSN22205554 1384 COSMIC
COSN28411408 1395 COSMIC
COSN2485085 1405 COSMIC
COSN19360730 1581 COSMIC
COSN25977632 1602 COSMIC
COSN8805670 1690 COSMIC
COSN20446718 1809 COSMIC
COSN5228648 1848 COSMIC
COSN14699786 1856 COSMIC
COSN32056705 1932 COSMIC
COSN20104397 2020 COSMIC
COSN2237768 2020 COSMIC
COSN20537073 2031 COSMIC
COSN15966894 2115 COSMIC
COSN30220471 2276 COSMIC
COSN5664159 2351 COSMIC
COSN19449462 2456 COSMIC
COSN25456766 2460 COSMIC
COSN15151925 2670 COSMIC
COSN26384432 2760 COSMIC
COSN9511811 2958 COSMIC
COSN26285421 2967 COSMIC
COSN2237767 3167 COSMIC
COSN2237766 3231 COSMIC
COSN15752282 3847 COSMIC
COSN20874241 3901 COSMIC
COSN9317491 3977 COSMIC
COSN19286308 4172 COSMIC
COSN6894087 4339 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1490866688 1 dbSNP
rs182941938 6 dbSNP
rs759141350 7 dbSNP
rs1430695785 11 dbSNP
rs1355482621 15 dbSNP
rs751371189 16 dbSNP
rs917073917 18 dbSNP
rs1053629983 19 dbSNP
rs41358550 20 dbSNP
rs1277158129 21 dbSNP
rs762864508 23 dbSNP
rs773186218 25 dbSNP
rs1323573211 31 dbSNP
rs1232797470 32 dbSNP
rs1405309835 45 dbSNP
rs764128307 47 dbSNP
rs760775659 48 dbSNP
rs981312125 52 dbSNP
rs1428161403 63 dbSNP
rs969955761 67 dbSNP
rs915859919 68 dbSNP
rs1261457378 70 dbSNP
rs1219485192 71 dbSNP
rs570671445 76 dbSNP
rs1352028173 81 dbSNP
rs767923608 88 dbSNP
rs1344701477 92 dbSNP
rs190701568 94 dbSNP
rs200527093 100 dbSNP
rs1234978232 101 dbSNP
rs1313371325 106 dbSNP
rs983789313 107 dbSNP
rs1283559839 111 dbSNP
rs1026036355 118 dbSNP
rs952472825 120 dbSNP
rs568087686 125 dbSNP
rs1189825882 131 dbSNP
rs993663933 132 dbSNP
rs961526067 134 dbSNP
rs1455069989 137 dbSNP
rs186704081 139 dbSNP
rs1008383288 144 dbSNP
rs528500916 146 dbSNP
rs890022424 169 dbSNP
rs1398460105 177 dbSNP
rs181160645 179 dbSNP
rs1011552749 195 dbSNP
rs893138794 196 dbSNP
rs1053176169 200 dbSNP
rs1323608987 201 dbSNP
rs1370040720 204 dbSNP
rs552883495 212 dbSNP
rs775553161 221 dbSNP
rs1045578673 226 dbSNP
rs948560161 235 dbSNP
rs76257165 239 dbSNP
rs563918602 244 dbSNP
rs544288431 247 dbSNP
rs984720787 248 dbSNP
rs575431343 261 dbSNP
rs1219710267 265 dbSNP
rs951714318 271 dbSNP
rs918923482 283 dbSNP
rs971793079 287 dbSNP
rs1195980206 302 dbSNP
rs561791039 302 dbSNP
rs1440783728 307 dbSNP
rs1408130463 309 dbSNP
rs1018677163 310 dbSNP
rs1162375804 311 dbSNP
rs917146723 313 dbSNP
rs1461772267 314 dbSNP
rs1195763838 322 dbSNP
rs1327764862 324 dbSNP
rs1333889318 325 dbSNP
rs1056915737 329 dbSNP
rs1280176921 331 dbSNP
rs1008330971 337 dbSNP
rs954229580 341 dbSNP
rs1447885482 346 dbSNP
rs550049312 348 dbSNP
rs1215927573 350 dbSNP
rs1012250366 355 dbSNP
rs190682330 365 dbSNP
rs1199203346 370 dbSNP
rs1483959259 378 dbSNP
rs893096976 378 dbSNP
rs983841782 379 dbSNP
rs745627628 380 dbSNP
rs1185259960 384 dbSNP
rs4141336 398 dbSNP
rs907269450 400 dbSNP
rs1166816622 410 dbSNP
rs144451857 411 dbSNP
rs962636521 414 dbSNP
rs1329499240 418 dbSNP
rs1356290376 433 dbSNP
rs1413031916 437 dbSNP
rs1315674055 441 dbSNP
rs770503394 448 dbSNP
rs894323195 449 dbSNP
rs185879325 456 dbSNP
rs1019190009 457 dbSNP
rs1268768141 483 dbSNP
rs1339162626 485 dbSNP
rs987677945 488 dbSNP
rs1275727396 490 dbSNP
rs1483716869 505 dbSNP
rs953519680 506 dbSNP
rs1256269259 507 dbSNP
rs748905566 508 dbSNP
rs1189246337 517 dbSNP
rs148689698 528 dbSNP
rs1000693273 546 dbSNP
rs1397694518 558 dbSNP
rs1168370963 564 dbSNP
rs777217639 565 dbSNP
rs1432859785 566 dbSNP
rs1337465440 571 dbSNP
rs1465355689 572 dbSNP
rs1398396035 573 dbSNP
rs930550482 579 dbSNP
rs919213504 582 dbSNP
rs755609576 596 dbSNP
rs1272346845 597 dbSNP
rs895774945 603 dbSNP
rs944409843 609 dbSNP
rs1368206670 616 dbSNP
rs113185502 619 dbSNP
rs548123741 620 dbSNP
rs374635106 625 dbSNP
rs985855665 631 dbSNP
rs954176979 633 dbSNP
rs1440041038 640 dbSNP
rs1249706206 650 dbSNP
rs937223898 654 dbSNP
rs1172962974 658 dbSNP
rs536875077 660 dbSNP
rs1436664471 664 dbSNP
rs1156985620 666 dbSNP
rs1384509437 684 dbSNP
rs1048198061 692 dbSNP
rs1369301999 697 dbSNP
rs780509724 698 dbSNP
rs1304819245 702 dbSNP
rs990367512 704 dbSNP
rs1234770978 705 dbSNP
rs145120758 709 dbSNP
rs1258509942 710 dbSNP
rs1349466387 712 dbSNP
rs1269735201 726 dbSNP
rs1466996329 728 dbSNP
rs1192856376 752 dbSNP
rs957844306 757 dbSNP
rs1434895371 758 dbSNP
rs1179744962 769 dbSNP
rs1259594163 772 dbSNP
rs12671252 789 dbSNP
rs374332456 795 dbSNP
rs1282185718 799 dbSNP
rs1246993944 809 dbSNP
rs1392683731 812 dbSNP
rs999239174 815 dbSNP
rs1461263592 821 dbSNP
rs1327066670 822 dbSNP
rs74774497 842 dbSNP
rs1390208175 843 dbSNP
rs972839484 849 dbSNP
rs1024363163 853 dbSNP
rs1013010517 855 dbSNP
rs894606067 856 dbSNP
rs545726919 858 dbSNP
rs1410721600 861 dbSNP
rs1212822904 872 dbSNP
rs930521115 882 dbSNP
rs953575271 886 dbSNP
rs1489402902 888 dbSNP
rs897715956 893 dbSNP
rs1036298860 897 dbSNP
rs1161818607 900 dbSNP
rs1419776866 901 dbSNP
rs566070328 904 dbSNP
rs1386423316 905 dbSNP
rs1475043819 908 dbSNP
rs1166072242 914 dbSNP
rs1178493541 915 dbSNP
rs1352032304 916 dbSNP
rs765576193 917 dbSNP
rs1460874818 929 dbSNP
rs1173005962 931 dbSNP
rs1298137389 945 dbSNP
rs552556242 946 dbSNP
rs978926592 960 dbSNP
rs985803809 961 dbSNP
rs969228780 964 dbSNP
rs149873736 965 dbSNP
rs915025672 967 dbSNP
rs990705368 968 dbSNP
rs1293652713 977 dbSNP
rs957580275 982 dbSNP
rs1225100193 990 dbSNP
rs1032312823 1005 dbSNP
rs1250693648 1005 dbSNP
rs1207378350 1008 dbSNP
rs563608084 1009 dbSNP
rs570119225 1010 dbSNP
rs1188953566 1011 dbSNP
rs1287543914 1014 dbSNP
rs971350520 1025 dbSNP
rs1170289861 1027 dbSNP
rs1374125656 1037 dbSNP
rs1432238591 1037 dbSNP
rs1359807422 1039 dbSNP
rs1373143518 1039 dbSNP
rs1413735051 1043 dbSNP
rs550374850 1046 dbSNP
rs1001421677 1053 dbSNP
rs905765987 1057 dbSNP
rs1294677407 1067 dbSNP
rs1024310889 1078 dbSNP
rs1230580848 1081 dbSNP
rs1278227731 1091 dbSNP
rs543754657 1092 dbSNP
rs1443283718 1093 dbSNP
rs1239447428 1096 dbSNP
rs896931571 1097 dbSNP
rs6971394 1099 dbSNP
rs943728769 1106 dbSNP
rs541587629 1107 dbSNP
rs764323872 1128 dbSNP
rs985094847 1129 dbSNP
rs1407150126 1139 dbSNP
rs1433564203 1148 dbSNP
rs1366538584 1153 dbSNP
rs1360535090 1167 dbSNP
rs932237905 1176 dbSNP
rs922158439 1180 dbSNP
rs1365693970 1184 dbSNP
rs1437144799 1190 dbSNP
rs541991257 1191 dbSNP
rs62465930 1204 dbSNP
rs1418377091 1207 dbSNP
rs968913475 1213 dbSNP
rs913353813 1216 dbSNP
rs1280904116 1218 dbSNP
rs1315315611 1220 dbSNP
rs988921798 1225 dbSNP
rs897669535 1228 dbSNP
rs1158628193 1230 dbSNP
rs1466553017 1231 dbSNP
rs1192232010 1243 dbSNP
rs1477377625 1249 dbSNP
rs1455137725 1257 dbSNP
rs1191238346 1273 dbSNP
rs554667627 1273 dbSNP
rs781114060 1275 dbSNP
rs1035673376 1277 dbSNP
rs1157961130 1279 dbSNP
rs1389024833 1283 dbSNP
rs1008772342 1284 dbSNP
rs890412115 1286 dbSNP
rs1050037169 1289 dbSNP
rs1201089535 1301 dbSNP
rs181383028 1305 dbSNP
rs1371299617 1307 dbSNP
rs969977437 1310 dbSNP
rs146199514 1311 dbSNP
rs1331599795 1313 dbSNP
rs1262172948 1319 dbSNP
rs1272993999 1328 dbSNP
rs1469288864 1340 dbSNP
rs914950944 1341 dbSNP
rs1247909723 1352 dbSNP
rs1468163313 1359 dbSNP
rs1318647973 1362 dbSNP
rs1053552873 1364 dbSNP
rs936132458 1367 dbSNP
rs1162486794 1368 dbSNP
rs757205482 1372 dbSNP
rs1224419905 1385 dbSNP
rs924804679 1394 dbSNP
rs977623423 1395 dbSNP
rs1344315721 1400 dbSNP
rs995785367 1402 dbSNP
rs190688771 1411 dbSNP
rs746804487 1417 dbSNP
rs6963266 1418 dbSNP
rs1352767172 1422 dbSNP
rs1007992772 1425 dbSNP
rs890853984 1429 dbSNP
rs1231742142 1430 dbSNP
rs1049444884 1437 dbSNP
rs917535681 1439 dbSNP
rs1230465978 1441 dbSNP
rs1398759937 1443 dbSNP
rs559003312 1446 dbSNP
rs958754368 1448 dbSNP
rs1437822495 1460 dbSNP
rs1203809174 1477 dbSNP
rs1251955029 1479 dbSNP
rs1483818066 1483 dbSNP
rs1185370137 1484 dbSNP
rs1416842218 1487 dbSNP
rs1028126274 1492 dbSNP
rs1319486186 1502 dbSNP
rs543205518 1505 dbSNP
rs994940187 1513 dbSNP
rs1417277498 1514 dbSNP
rs759467408 1526 dbSNP
rs1409371850 1532 dbSNP
rs1308692238 1536 dbSNP
rs932290203 1538 dbSNP
rs1422389951 1539 dbSNP
rs754077110 1544 dbSNP
rs1312504477 1547 dbSNP
rs1178202852 1558 dbSNP
rs1480540106 1559 dbSNP
rs141649437 1560 dbSNP
rs1268861262 1571 dbSNP
rs1191214240 1573 dbSNP
rs1229845607 1584 dbSNP
rs1274661642 1589 dbSNP
rs947594270 1591 dbSNP
rs1208197792 1593 dbSNP
rs56302843 1594 dbSNP
rs748953635 1595 dbSNP
rs988916702 1597 dbSNP
rs1050322253 1598 dbSNP
rs1242636332 1600 dbSNP
rs1475016329 1604 dbSNP
rs1169176820 1607 dbSNP
rs960139219 1613 dbSNP
rs1432960662 1614 dbSNP
rs138419154 1618 dbSNP
rs1403179013 1631 dbSNP
rs1416422593 1634 dbSNP
rs980106478 1635 dbSNP
rs1326229615 1637 dbSNP
rs1436404346 1637 dbSNP
rs970029668 1642 dbSNP
rs995768379 1647 dbSNP
rs1205889566 1649 dbSNP
rs777463044 1659 dbSNP
rs1053906081 1681 dbSNP
rs1324521822 1696 dbSNP
rs935090724 1699 dbSNP
rs923717338 1717 dbSNP
rs769336985 1719 dbSNP
rs950223413 1730 dbSNP
rs1271312391 1731 dbSNP
rs1447919796 1741 dbSNP
rs1356967862 1743 dbSNP
rs1338123037 1746 dbSNP
rs535131088 1749 dbSNP
rs1015444648 1751 dbSNP
rs6979945 1766 dbSNP
rs991755431 1773 dbSNP
rs958924474 1787 dbSNP
rs920610322 1790 dbSNP
rs1430117675 1801 dbSNP
rs1419904165 1808 dbSNP
rs10486985 1809 dbSNP
rs1384613453 1810 dbSNP
rs750475413 1812 dbSNP
rs1222171947 1818 dbSNP
rs1049495904 1821 dbSNP
rs1323036801 1823 dbSNP
rs1392911232 1831 dbSNP
rs962145130 1833 dbSNP
rs1299933539 1835 dbSNP
rs1014986164 1840 dbSNP
rs1008661140 1843 dbSNP
rs1241426367 1848 dbSNP
rs954557052 1849 dbSNP
rs1028832119 1852 dbSNP
rs538682722 1855 dbSNP
rs570346044 1860 dbSNP
rs1234879636 1863 dbSNP
rs1277424334 1864 dbSNP
rs768066161 1866 dbSNP
rs996561182 1867 dbSNP
rs903528545 1875 dbSNP
rs996051129 1881 dbSNP
rs1269832273 1883 dbSNP
rs1043758752 1897 dbSNP
rs758916269 1904 dbSNP
rs879504594 1905 dbSNP
rs1434982069 1907 dbSNP
rs1257705810 1908 dbSNP
rs1202638264 1910 dbSNP
rs1179846594 1912 dbSNP
rs1031996699 1915 dbSNP
rs947683569 1922 dbSNP
rs913456959 1930 dbSNP
rs1473080084 1941 dbSNP
rs1161784884 1948 dbSNP
rs1053245464 1949 dbSNP
rs187064863 1961 dbSNP
rs79422781 1966 dbSNP
rs1196276412 1968 dbSNP
rs1294638528 1972 dbSNP
rs1387998042 1975 dbSNP
rs1326362824 1980 dbSNP
rs1381205862 1984 dbSNP
rs1228685200 1997 dbSNP
rs902244986 1998 dbSNP
rs1452733049 1999 dbSNP
rs1375466837 2007 dbSNP
rs1046200123 2014 dbSNP
rs1296113892 2017 dbSNP
rs760086406 2019 dbSNP
rs867918196 2021 dbSNP
rs530313511 2023 dbSNP
rs948779495 2028 dbSNP
rs199679908 2030 dbSNP
rs201762313 2031 dbSNP
rs200367971 2032 dbSNP
rs113126131 2038 dbSNP
rs1423611718 2038 dbSNP
rs755952795 2038 dbSNP
rs75819913 2038 dbSNP
rs769061687 2038 dbSNP
rs1056020017 2045 dbSNP
rs1370701969 2050 dbSNP
rs974454901 2051 dbSNP
rs1403332514 2052 dbSNP
rs961340237 2054 dbSNP
rs937606134 2056 dbSNP
rs920880943 2057 dbSNP
rs1369429172 2058 dbSNP
rs1015910844 2064 dbSNP
rs1309477982 2067 dbSNP
rs1387019563 2068 dbSNP
rs1184091608 2072 dbSNP
rs986663180 2073 dbSNP
rs1445344080 2103 dbSNP
rs1313243380 2105 dbSNP
rs370078299 2106 dbSNP
rs1323396813 2109 dbSNP
rs181002947 2114 dbSNP
rs547935256 2116 dbSNP
rs1237619342 2117 dbSNP
rs1273947414 2118 dbSNP
rs1342970529 2118 dbSNP
rs1175744753 2119 dbSNP
rs1255655444 2124 dbSNP
rs1481736313 2128 dbSNP
rs1028128246 2129 dbSNP
rs940705402 2146 dbSNP
rs139887015 2155 dbSNP
rs1427212708 2158 dbSNP
rs1859174 2159 dbSNP
rs545769194 2165 dbSNP
rs1388936936 2167 dbSNP
rs1021985937 2169 dbSNP
rs1357651001 2174 dbSNP
rs754055962 2176 dbSNP
rs954505062 2179 dbSNP
rs892082846 2192 dbSNP
rs1465268239 2193 dbSNP
rs1028779724 2195 dbSNP
rs1053298028 2197 dbSNP
rs1294624430 2199 dbSNP
rs1247288980 2201 dbSNP
rs1352400474 2203 dbSNP
rs938896874 2206 dbSNP
rs907389247 2208 dbSNP
rs1296800232 2215 dbSNP
rs764378824 2216 dbSNP
rs532052285 2220 dbSNP
rs373321667 2229 dbSNP
rs1278339976 2233 dbSNP
rs1311808365 2249 dbSNP
rs1392832523 2250 dbSNP
rs1032694160 2258 dbSNP
rs563239631 2270 dbSNP
rs940006623 2271 dbSNP
rs999179019 2273 dbSNP
rs1249171943 2276 dbSNP
rs543317707 2280 dbSNP
rs902195751 2282 dbSNP
rs574254884 2283 dbSNP
rs77984596 2291 dbSNP
rs760939040 2296 dbSNP
rs894937667 2298 dbSNP
rs62465929 2299 dbSNP
rs1271340839 2303 dbSNP
rs1164189527 2307 dbSNP
rs572477953 2312 dbSNP
rs1319722179 2315 dbSNP
rs1859173 2316 dbSNP
rs899390813 2320 dbSNP
rs1363362566 2321 dbSNP
rs1367041294 2331 dbSNP
rs775066274 2341 dbSNP
rs1038372761 2346 dbSNP
rs967853788 2348 dbSNP
rs1022455581 2355 dbSNP
rs1327412564 2360 dbSNP
rs1208487735 2362 dbSNP
rs539011955 2363 dbSNP
rs1466620337 2369 dbSNP
rs1420893012 2370 dbSNP
rs1408986108 2371 dbSNP
rs759459402 2376 dbSNP
rs1191328487 2383 dbSNP
rs552233566 2387 dbSNP
rs189141358 2388 dbSNP
rs1158122155 2390 dbSNP
rs1412468773 2393 dbSNP
rs1458716525 2399 dbSNP
rs1321516717 2405 dbSNP
rs1190788147 2410 dbSNP
rs532211484 2414 dbSNP
rs987470557 2428 dbSNP
rs933397699 2451 dbSNP
rs1271466556 2462 dbSNP
rs1228066024 2472 dbSNP
rs892128695 2478 dbSNP
rs922047107 2479 dbSNP
rs556847064 2481 dbSNP
rs1331695415 2488 dbSNP
rs1034614830 2491 dbSNP
rs1488243216 2504 dbSNP
rs974582645 2505 dbSNP
rs1240568773 2508 dbSNP
rs536954788 2511 dbSNP
rs907440315 2514 dbSNP
rs1300196710 2531 dbSNP
rs1221285743 2546 dbSNP
rs1481843385 2547 dbSNP
rs958132239 2548 dbSNP
rs1252195806 2549 dbSNP
rs948885900 2563 dbSNP
rs1032233475 2565 dbSNP
rs898611827 2566 dbSNP
rs978424067 2573 dbSNP
rs567825184 2578 dbSNP
rs547949449 2579 dbSNP
rs1166972888 2587 dbSNP
rs966329978 2594 dbSNP
rs908560270 2595 dbSNP
rs1024645916 2600 dbSNP
rs1051071998 2604 dbSNP
rs1290486289 2606 dbSNP
rs1013293034 2610 dbSNP
rs1364406617 2612 dbSNP
rs1176039452 2613 dbSNP
rs1446273461 2616 dbSNP
rs146122383 2617 dbSNP
rs1033870614 2620 dbSNP
rs565759757 2635 dbSNP
rs866844897 2641 dbSNP
rs1293274795 2644 dbSNP
rs1001681673 2649 dbSNP
rs563494007 2656 dbSNP
rs1203929739 2660 dbSNP
rs142987828 2667 dbSNP
rs1439259320 2668 dbSNP
rs1185099852 2670 dbSNP
rs1236729207 2675 dbSNP
rs1473056183 2678 dbSNP
rs1183557670 2682 dbSNP
rs1260300789 2689 dbSNP
rs899336987 2693 dbSNP
rs1169381023 2697 dbSNP
rs117865726 2699 dbSNP
rs1005541470 2702 dbSNP
rs1254876972 2718 dbSNP
rs1450733674 2725 dbSNP
rs1296066615 2732 dbSNP
rs1201462500 2738 dbSNP
rs886725061 2742 dbSNP
rs956427114 2749 dbSNP
rs1297738653 2752 dbSNP
rs762781502 2755 dbSNP
rs1051701050 2760 dbSNP
rs933345342 2761 dbSNP
rs921994761 2765 dbSNP
rs148163513 2778 dbSNP
rs936486095 2786 dbSNP
rs1297664958 2793 dbSNP
rs1392128951 2798 dbSNP
rs140439520 2806 dbSNP
rs1023629598 2811 dbSNP
rs1013122030 2815 dbSNP
rs1416510661 2819 dbSNP
rs1319036849 2821 dbSNP
rs1336155913 2826 dbSNP
rs1468245207 2830 dbSNP
rs925112728 2834 dbSNP
rs977991480 2838 dbSNP
rs1327711962 2839 dbSNP
rs898660207 2842 dbSNP
rs1038510246 2843 dbSNP
rs574792522 2853 dbSNP
rs966611006 2855 dbSNP
rs917869591 2861 dbSNP
rs1461817145 2867 dbSNP
rs549632694 2873 dbSNP
rs887174445 2880 dbSNP
rs1209314937 2884 dbSNP
rs1196012186 2886 dbSNP
rs1263865734 2889 dbSNP
rs1449955622 2889 dbSNP
rs1051126151 2890 dbSNP
rs1242056046 2891 dbSNP
rs959040318 2903 dbSNP
rs529962112 2910 dbSNP
rs533199976 2919 dbSNP
rs933971781 2919 dbSNP
rs1462213567 2929 dbSNP
rs995666212 2933 dbSNP
rs1474016422 2934 dbSNP
rs1279204301 2942 dbSNP
rs560874136 2957 dbSNP
rs111366767 2958 dbSNP
rs1005036019 2961 dbSNP
rs1337259354 2980 dbSNP
rs915072462 2983 dbSNP
rs369848448 2985 dbSNP
rs1252822043 2994 dbSNP
rs769463736 3001 dbSNP
rs1328232332 3002 dbSNP
rs1228145954 3011 dbSNP
rs1262412249 3018 dbSNP
rs112104928 3020 dbSNP
rs1209279330 3027 dbSNP
rs1051982984 3049 dbSNP
rs927703080 3057 dbSNP
rs981775155 3062 dbSNP
rs369793613 3063 dbSNP
rs541111447 3068 dbSNP
rs1450584565 3072 dbSNP
rs1473130329 3075 dbSNP
rs900512166 3079 dbSNP
rs1013601007 3080 dbSNP
rs149342498 3081 dbSNP
rs776119702 3091 dbSNP
rs1457886068 3092 dbSNP
rs1337698687 3094 dbSNP
rs1162075811 3100 dbSNP
rs1365695271 3101 dbSNP
rs1039079775 3107 dbSNP
rs962971397 3110 dbSNP
rs185079729 3117 dbSNP
rs1349562467 3121 dbSNP
rs1169997608 3123 dbSNP
rs191801159 3124 dbSNP
rs188527672 3125 dbSNP
rs558648200 3126 dbSNP
rs1243999553 3128 dbSNP
rs998231007 3131 dbSNP
rs1243193780 3136 dbSNP
rs1203211806 3144 dbSNP
rs1180695327 3158 dbSNP
rs1483543167 3160 dbSNP
rs574372664 3161 dbSNP
rs1254537065 3163 dbSNP
rs1423703785 3164 dbSNP
rs1039679200 3165 dbSNP
rs1385252322 3169 dbSNP
rs1252473334 3170 dbSNP
rs1166249544 3173 dbSNP
rs1369518338 3176 dbSNP
rs1196166479 3179 dbSNP
rs1355330667 3190 dbSNP
rs1299624874 3195 dbSNP
rs1289533152 3200 dbSNP
rs1248053265 3206 dbSNP
rs1399841467 3218 dbSNP
rs1361738319 3222 dbSNP
rs1315821031 3231 dbSNP
rs1395320666 3242 dbSNP
rs946644662 3246 dbSNP
rs992084573 3252 dbSNP
rs1441834430 3256 dbSNP
rs1334219565 3257 dbSNP
rs1052726408 3260 dbSNP
rs1331056158 3260 dbSNP
rs779450692 3262 dbSNP
rs866309927 3269 dbSNP
rs937621737 3271 dbSNP
rs554208322 3272 dbSNP
rs1483135159 3284 dbSNP
rs981827274 3297 dbSNP
rs1245502958 3300 dbSNP
rs111312990 3301 dbSNP
rs571752580 3302 dbSNP
rs1301885741 3304 dbSNP
rs962761550 3316 dbSNP
rs1015366138 3324 dbSNP
rs1172100132 3325 dbSNP
rs552211193 3328 dbSNP
rs950897040 3329 dbSNP
rs1408168271 3330 dbSNP
rs17156625 3331 dbSNP
rs1319925755 3335 dbSNP
rs1157467630 3345 dbSNP
rs569285138 3347 dbSNP
rs1362754315 3348 dbSNP
rs778233364 3350 dbSNP
rs900794254 3354 dbSNP
rs1299446036 3360 dbSNP
rs1468104144 3361 dbSNP
rs1365216645 3371 dbSNP
rs1182022263 3377 dbSNP
rs1311896538 3381 dbSNP
rs1490139539 3382 dbSNP
rs951530216 3383 dbSNP
rs1265436968 3388 dbSNP
rs184595601 3389 dbSNP
rs1208689395 3392 dbSNP
rs529673211 3398 dbSNP
rs574214003 3401 dbSNP
rs903917943 3404 dbSNP
rs1187824912 3411 dbSNP
rs998283158 3415 dbSNP
rs1042513829 3419 dbSNP
rs192045293 3423 dbSNP
rs1432276768 3425 dbSNP
rs1223300751 3433 dbSNP
rs1431202208 3438 dbSNP
rs1455512522 3441 dbSNP
rs79283508 3451 dbSNP
rs1018713688 3452 dbSNP
rs1239999420 3458 dbSNP
rs1010892794 3461 dbSNP
rs1291897430 3462 dbSNP
rs1367140372 3466 dbSNP
rs767764600 3467 dbSNP
rs564939306 3470 dbSNP
rs1285544434 3474 dbSNP
rs893747221 3482 dbSNP
rs1301671448 3483 dbSNP
rs1407361031 3485 dbSNP
rs545484577 3487 dbSNP
rs1056349840 3488 dbSNP
rs1319326142 3489 dbSNP
rs935208229 3494 dbSNP
rs576631683 3500 dbSNP
rs189172360 3514 dbSNP
rs1244526723 3524 dbSNP
rs1199703460 3525 dbSNP
rs906381358 3525 dbSNP
rs937917191 3529 dbSNP
rs1046193722 3530 dbSNP
rs755065792 3531 dbSNP
rs1366748975 3542 dbSNP
rs974127846 3544 dbSNP
rs941703072 3547 dbSNP
rs1349406576 3551 dbSNP
rs183809562 3553 dbSNP
rs751494952 3554 dbSNP
rs908257855 3558 dbSNP
rs983040768 3562 dbSNP
rs982505710 3570 dbSNP
rs1386470414 3578 dbSNP
rs552614451 3583 dbSNP
rs1030455220 3591 dbSNP
rs1280549561 3596 dbSNP
rs1376139401 3596 dbSNP
rs536439985 3603 dbSNP
rs976256620 3603 dbSNP
rs1479905374 3621 dbSNP
rs1358123943 3638 dbSNP
rs1029854276 3644 dbSNP
rs567912953 3645 dbSNP
rs1481890763 3646 dbSNP
rs1181158337 3651 dbSNP
rs976899569 3651 dbSNP
rs1471095102 3657 dbSNP
rs554399303 3661 dbSNP
rs1201339461 3668 dbSNP
rs1480604743 3685 dbSNP
rs965318626 3686 dbSNP
rs1241475480 3691 dbSNP
rs1413098465 3694 dbSNP
rs1445306041 3701 dbSNP
rs1165625610 3703 dbSNP
rs1017880778 3705 dbSNP
rs1018351903 3707 dbSNP
rs1329908029 3715 dbSNP
rs1001250245 3728 dbSNP
rs540581762 3732 dbSNP
rs376050838 3741 dbSNP
rs1021011512 3746 dbSNP
rs1246029219 3750 dbSNP
rs1323070425 3753 dbSNP
rs1009653175 3755 dbSNP
rs1194901012 3756 dbSNP
rs1281550229 3760 dbSNP
rs762755232 3765 dbSNP
rs1273370942 3769 dbSNP
rs1439361496 3772 dbSNP
rs1207833201 3779 dbSNP
rs999410220 3784 dbSNP
rs1368688398 3793 dbSNP
rs578099469 3804 dbSNP
rs1056296270 3807 dbSNP
rs906443605 3808 dbSNP
rs1046246399 3814 dbSNP
rs1012076182 3816 dbSNP
rs894930037 3817 dbSNP
rs548047669 3831 dbSNP
rs1333967922 3832 dbSNP
rs1407445422 3853 dbSNP
rs558093649 3867 dbSNP
rs1455073010 3868 dbSNP
rs1338076803 3879 dbSNP
rs1318393803 3880 dbSNP
rs941741658 3881 dbSNP
rs907549987 3883 dbSNP
rs1270401452 3885 dbSNP
rs1047405996 3891 dbSNP
rs930233889 3905 dbSNP
rs534355447 3911 dbSNP
rs1038300939 3915 dbSNP
rs565685143 3923 dbSNP
rs964240656 3942 dbSNP
rs1446488308 3948 dbSNP
rs1194074329 3951 dbSNP
rs764940724 3956 dbSNP
rs1470140493 3957 dbSNP
rs911338632 3962 dbSNP
rs1418498447 3964 dbSNP
rs989586914 3968 dbSNP
rs1430462165 3970 dbSNP
rs1471202486 3980 dbSNP
rs958332187 3988 dbSNP
rs1388627815 3992 dbSNP
rs555877224 3994 dbSNP
rs535839397 3999 dbSNP
rs1243973263 4010 dbSNP
rs1046756726 4013 dbSNP
rs761516342 4014 dbSNP
rs933735694 4015 dbSNP
rs1205783417 4019 dbSNP
rs1266160927 4022 dbSNP
rs1349918968 4031 dbSNP
rs1205765442 4039 dbSNP
rs776249523 4040 dbSNP
rs1230242017 4046 dbSNP
rs1313196506 4047 dbSNP
rs1198966356 4048 dbSNP
rs1269972442 4053 dbSNP
rs976204085 4067 dbSNP
rs75443649 4073 dbSNP
rs910766617 4077 dbSNP
rs979709814 4085 dbSNP
rs547628091 4087 dbSNP
rs562085118 4088 dbSNP
rs527604627 4093 dbSNP
rs1005989069 4097 dbSNP
rs886171180 4098 dbSNP
rs866217063 4099 dbSNP
rs1020957811 4100 dbSNP
rs1009599346 4103 dbSNP
rs1047457878 4105 dbSNP
rs960761707 4107 dbSNP
rs932964656 4111 dbSNP
rs1451323916 4117 dbSNP
rs552174738 4118 dbSNP
rs1239716482 4128 dbSNP
rs1281285244 4133 dbSNP
rs1221922582 4139 dbSNP
rs1354346409 4139 dbSNP
rs1041300219 4142 dbSNP
rs1490914201 4148 dbSNP
rs1338348015 4154 dbSNP
rs1250285962 4156 dbSNP
rs1002415293 4158 dbSNP
rs905030876 4160 dbSNP
rs1184608361 4176 dbSNP
rs1364967100 4190 dbSNP
rs1038658219 4197 dbSNP
rs746495862 4198 dbSNP
rs1365784810 4206 dbSNP
rs887060663 4208 dbSNP
rs1046702660 4218 dbSNP
rs990029821 4226 dbSNP
rs958179142 4232 dbSNP
rs933681786 4244 dbSNP
rs978104876 4245 dbSNP
rs1411389057 4249 dbSNP
rs970707175 4259 dbSNP
rs1338701956 4267 dbSNP
rs1245304400 4286 dbSNP
rs1315885436 4292 dbSNP
rs774820320 4301 dbSNP
rs1361800937 4302 dbSNP
rs1420147137 4302 dbSNP
rs1251045520 4314 dbSNP
rs1481172765 4323 dbSNP
rs1162807091 4336 dbSNP
rs1039468748 4340 dbSNP
rs771491027 4341 dbSNP
rs1461303416 4343 dbSNP
rs1182387825 4348 dbSNP
rs1385344874 4358 dbSNP
rs6956122 4360 dbSNP
rs569726953 4373 dbSNP
rs959528543 4382 dbSNP
rs531578700 4389 dbSNP
rs910718194 4394 dbSNP
rs1016122674 4399 dbSNP
rs1299710309 4402 dbSNP
rs562967663 4407 dbSNP
rs1451857605 4408 dbSNP
rs1337425912 4415 dbSNP
rs1385092047 4416 dbSNP
rs1026066456 4417 dbSNP
rs886223668 4417 dbSNP
rs550038913 4419 dbSNP
rs543147709 4421 dbSNP
rs878868349 4427 dbSNP
rs1230040330 4429 dbSNP
rs529893833 4430 dbSNP
rs914180076 4433 dbSNP
rs1323400511 4446 dbSNP
rs1202872760 4454 dbSNP
rs1204865791 4460 dbSNP
rs1243153855 4465 dbSNP
rs901514860 4474 dbSNP
rs1309595127 4481 dbSNP
rs1039079414 4484 dbSNP
rs1428800666 4485 dbSNP
rs942983300 4487 dbSNP
rs1245849994 4489 dbSNP
rs560303181 4502 dbSNP
rs1426983819 4509 dbSNP
rs1469170099 4514 dbSNP
rs6955913 4516 dbSNP
rs1408286395 4527 dbSNP
rs1316526744 4530 dbSNP
rs1228587389 4532 dbSNP
rs1372172065 4535 dbSNP
rs541300258 4537 dbSNP
rs960709348 4550 dbSNP
rs1288413023 4561 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions islets
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO. ...

- Kameswaran V; Bramswig NC; McKenna LB; Penn et al., 2014, Cell metabolism.

Article - Kameswaran V; Bramswig NC; McKenna LB; Penn et al.
- Cell metabolism, 2014
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing beta cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the pathogenesis of human T2DM, we sequenced the small RNAs of human islets from diabetic and nondiabetic organ donors. We identified a cluster of microRNAs in an imprinted locus on human chromosome 14q32 that is highly and specifically expressed in human beta cells and dramatically downregulated in islets from T2DM organ donors. The downregulation of this locus strongly correlates with hypermethylation of its promoter. Using HITS-CLIP for the essential RISC-component Argonaute, we identified disease-relevant targets of the chromosome 14q32 microRNAs, such as IAPP and TP53INP1, that cause increased beta cell apoptosis upon overexpression in human islets. Our results support a role for microRNAs and their epigenetic control by DNA methylation in the pathogenesis of T2DM.
LinkOut: [PMID: 24374217]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.521 4.5e-3 -0.568 1.9e-3 24 Click to see details
GSE42095 Differentiated embryonic stem cells 0.444 1.7e-2 0.346 5.3e-2 23 Click to see details
GSE19350 CNS germ cell tumors -0.573 2.6e-2 -0.203 2.6e-1 12 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.375 3.2e-2 -0.467 9.3e-3 25 Click to see details
GSE19536 Breast cancer 0.17 4.5e-2 0.238 8.6e-3 100 Click to see details
GSE28260 Renal cortex and medulla 0.473 5.1e-2 0.516 3.6e-2 13 Click to see details
GSE19783 ER+ ER+ breast cancer 0.327 8.0e-2 0.296 1.0e-1 20 Click to see details
GSE19783 ER- ER- breast cancer 0.109 1.7e-1 0.198 4.0e-2 79 Click to see details
GSE17498 Multiple myeloma -0.148 1.8e-1 -0.037 4.1e-1 40 Click to see details
GSE21687 Ependynoma primary tumors 0.07 2.9e-1 0.021 4.3e-1 64 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.078 3.7e-1 -0.168 2.4e-1 20 Click to see details
GSE32688 Pancreatic cancer 0.042 4.1e-1 0.029 4.4e-1 32 Click to see details
GSE32688 Pancreatic cancer 0.042 4.1e-1 0.029 4.4e-1 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
CHOL -0.589 0.05 -0.367 0.17 9 Click to see details
KIRP -0.297 0.05 -0.223 0.11 32 Click to see details
STAD -0.277 0.06 -0.275 0.06 32 Click to see details
KICH -0.269 0.1 -0.007 0.49 25 Click to see details
BLCA 0.321 0.1 0.276 0.13 18 Click to see details
UCEC 0.31 0.1 0.339 0.08 19 Click to see details
KIRC -0.139 0.13 -0.036 0.39 68 Click to see details
THCA 0.132 0.16 0.069 0.3 59 Click to see details
PCPG 0.852 0.18 1.000 0.5 3 Click to see details
COAD 0.35 0.2 0.429 0.14 8 Click to see details
LUAD 0.268 0.2 0.427 0.08 12 Click to see details
LUSC -0.135 0.21 -0.146 0.19 38 Click to see details
PAAD 0.503 0.25 0.600 0.2 4 Click to see details
LIHC -0.066 0.33 0.046 0.38 49 Click to see details
ESCA 0.14 0.34 0.236 0.24 11 Click to see details
BRCA -0.042 0.35 -0.087 0.22 84 Click to see details
HNSC -0.051 0.37 -0.114 0.24 42 Click to see details
CESC -0.242 0.42 -0.500 0.33 3 Click to see details
PRAD 0.026 0.43 0.151 0.15 50 Click to see details
PRAD 0.026 0.43 0.151 0.15 50 Click to see details
PRAD 0.026 0.43 0.151 0.15 50 Click to see details
113 hsa-miR-127-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT380928 ZNF264 zinc finger protein 264 2 2
MIRT439324 USP34 ubiquitin specific peptidase 34 1 1
MIRT439333 USP22 ubiquitin specific peptidase 22 1 1
MIRT439379 TTC37 tetratricopeptide repeat domain 37 1 1
MIRT439445 TMEM116 transmembrane protein 116 1 1
MIRT439498 SYNJ2 synaptojanin 2 1 1
MIRT439525 STBD1 starch binding domain 1 1 1
MIRT439562 SORL1 sortilin related receptor 1 1 1
MIRT439660 SF3B1 splicing factor 3b subunit 1 1 1
MIRT439749 ROGDI rogdi homolog 1 1
MIRT439836 RAB3B RAB3B, member RAS oncogene family 1 1
MIRT439923 PPL periplakin 1 1
MIRT439963 PKD1 polycystin 1, transient receptor potential channel interacting 1 1
MIRT439985 PHKG2 phosphorylase kinase catalytic subunit gamma 2 1 1
MIRT440029 PCLO piccolo presynaptic cytomatrix protein 1 1
MIRT440179 MTRNR2L8 MT-RNR2-like 8 1 1
MIRT440183 MTRNR2L4 MT-RNR2-like 4 1 1
MIRT440184 MTRNR2L6 MT-RNR2-like 6 1 1
MIRT440194 MTRNR2L1 MT-RNR2-like 1 1 1
MIRT440269 MBP myelin basic protein 1 1
MIRT440323 LIN7C lin-7 homolog C, crumbs cell polarity complex component 1 1
MIRT440331 LGALS8 galectin 8 1 1
MIRT440355 KLHL29 kelch like family member 29 1 1
MIRT440397 KDM6B lysine demethylase 6B 1 1
MIRT440411 KAT2B lysine acetyltransferase 2B 1 1
MIRT440424 ITCH itchy E3 ubiquitin protein ligase 1 1
MIRT440651 FBXO7 F-box protein 7 1 1
MIRT440773 DST dystonin 1 1
MIRT440824 DGKD diacylglycerol kinase delta 1 1
MIRT440914 COPA coatomer protein complex subunit alpha 1 1
MIRT441118 BBS4 Bardet-Biedl syndrome 4 1 1
MIRT441153 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 1 1
MIRT441193 ARID1A AT-rich interaction domain 1A 1 1
MIRT441260 ADM adrenomedullin 1 1
MIRT441282 ACTB actin beta 1 1
MIRT441306 ABHD2 abhydrolase domain containing 2 1 1
MIRT441860 TEX35 testis expressed 35 2 2
MIRT442190 CCDC132 VPS50, EARP/GARPII complex subunit 2 2
MIRT442886 RHCG Rh family C glycoprotein 2 2
MIRT444158 ZNF701 zinc finger protein 701 2 2
MIRT444506 ZNF525 zinc finger protein 525 2 2
MIRT444770 NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2 2
MIRT445830 SRSF11 serine and arginine rich splicing factor 11 2 2
MIRT445850 LRRC1 leucine rich repeat containing 1 2 2
MIRT445863 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT446161 C8A complement C8 alpha chain 2 2
MIRT447117 SLFN5 schlafen family member 5 2 2
MIRT447990 CDX1 caudal type homeobox 1 2 2
MIRT449032 ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 2 2
MIRT449295 SMIM19 small integral membrane protein 19 2 2
MIRT449541 PCDH9 protocadherin 9 2 2
MIRT449579 ZNF510 zinc finger protein 510 2 2
MIRT450062 SYT9 synaptotagmin 9 2 2
MIRT450437 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 2
MIRT450449 ZDHHC2 zinc finger DHHC-type containing 2 2 2
MIRT450695 RORA RAR related orphan receptor A 2 2
MIRT453654 RAB6C RAB6C, member RAS oncogene family 2 2
MIRT463771 YOD1 YOD1 deubiquitinase 2 2
MIRT468425 SETD1B SET domain containing 1B 2 2
MIRT468843 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT475594 HMGB2 high mobility group box 2 4 4
MIRT478284 DDX19A DEAD-box helicase 19A 2 2
MIRT487594 NKD2 naked cuticle homolog 2 2 4
MIRT493440 KANSL1 KAT8 regulatory NSL complex subunit 1 2 6
MIRT496169 RPL35A ribosomal protein L35a 2 4
MIRT497566 CCR6 C-C motif chemokine receptor 6 2 2
MIRT497917 BTG1 BTG anti-proliferation factor 1 2 2
MIRT498331 PRELID2 PRELI domain containing 2 2 2
MIRT498369 KLHL11 kelch like family member 11 2 2
MIRT498856 LITAF lipopolysaccharide induced TNF factor 2 2
MIRT505640 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT506128 PLRG1 pleiotropic regulator 1 2 4
MIRT512242 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT512489 ARID2 AT-rich interaction domain 2 2 2
MIRT525251 RNF213 ring finger protein 213 2 2
MIRT530197 ALX1 ALX homeobox 1 2 4
MIRT530551 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 2
MIRT534048 STC2 stanniocalcin 2 2 2
MIRT537508 FAM105A family with sequence similarity 105 member A 2 2
MIRT543005 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT543814 SNX10 sorting nexin 10 2 2
MIRT549303 ARID5B AT-rich interaction domain 5B 2 2
MIRT549407 ADIPOR2 adiponectin receptor 2 2 4
MIRT550547 ARSK arylsulfatase family member K 2 2
MIRT554319 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT554515 RUFY2 RUN and FYVE domain containing 2 2 2
MIRT559603 AMOT angiomotin 2 2
MIRT564844 ZBED3 zinc finger BED-type containing 3 2 2
MIRT566125 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT567484 FOXK1 forkhead box K1 2 2
MIRT576521 Txlna taxilin alpha 2 2
MIRT633635 CASC5 kinetochore scaffold 1 2 2
MIRT639325 C9orf41 carnosine N-methyltransferase 1 2 2
MIRT643174 MDM2 MDM2 proto-oncogene 2 2
MIRT651214 ZNF225 zinc finger protein 225 2 2
MIRT653039 STRIP2 striatin interacting protein 2 2 2
MIRT653042 STOX2 storkhead box 2 2 2
MIRT658769 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT666728 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT681223 DUSP19 dual specificity phosphatase 19 2 2
MIRT685562 SRD5A3 steroid 5 alpha-reductase 3 2 2
MIRT687434 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT688439 DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 2 2
MIRT692707 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT700552 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT704955 CBX2 chromobox 2 2 2
MIRT714524 ALKBH3 alkB homolog 3, alpha-ketoglutaratedependent dioxygenase 2 2
MIRT716225 DGKI diacylglycerol kinase iota 2 2
MIRT717953 MIA3 MIA family member 3, ER export factor 2 2
MIRT719902 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT732044 BLVRB biliverdin reductase B 3 1
MIRT733622 SNX5 sorting nexin 5 3 0
MIRT737210 CXCR4 C-X-C motif chemokine receptor 4 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-127 17beta-estradiol (E2) approved 5757 Quantitative real-time PCR rat breast 17700064 2007 down-regulated
miR-127 5-aza-2'-deoxycytidine (5-Aza-CdR) + 4-phenylbutyric acid (PBA) NULL NULL Microarray T24 human bladder cancer cells 16766263 2006 up-regulated
miR-127 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
miR-127-5p Glucose NULL 5793 Microarray endothelial cells 24394957 2014 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-127 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-mir-127 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-127-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-127-5p Palbociclib 5330286 NSC758247 approved resistant cell line (T47D)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-127-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM11)
hsa-miR-127-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-127-5p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-127-5p Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-127-5p Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR200)
hsa-miR-127-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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