miRTarBase - #MIRT440061


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pre-miRNA Information
pre-miRNA hsa-mir-412   
Genomic Coordinates chr14: 101065447 - 101065537
Synonyms MIRN412, hsa-mir-412, MIR412
Description Homo sapiens miR-412 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-412-3p
Sequence 54| ACUUCACCUGGUCCACUAGCCGU |76
Evidence Not_experimental
Experiments
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
rs61992671 18 GWAS
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs369997462 1 dbSNP
rs1439693090 7 dbSNP
rs1301668924 11 dbSNP
rs534204576 13 dbSNP
rs775386036 14 dbSNP
rs762832140 15 dbSNP
rs1203323285 16 dbSNP
rs61992671 18 dbSNP
rs1022012324 19 dbSNP
rs1207609936 20 dbSNP
rs139967426 21 dbSNP
rs539487075 22 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol OSBPL8   
Synonyms MST120, MSTP120, ORP8, OSBP10
Description oxysterol binding protein like 8
Transcript NM_001003712   
Other Transcripts NM_020841   
Expression
Putative miRNA Targets on OSBPL8
3'UTR of OSBPL8
(miRNA target sites are highlighted)		 
>OSBPL8|NM_001003712|3'UTR
   1 AAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGTTTGGTCTTTAT
  81 TAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTCA
 161 CACTGAAACAAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGA
 241 ATGTGTCTACATATGAGTATAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTG
 321 TATTCTATAGTATGTTCTGAGATATAATGTTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAAT
 401 CTATTTTCTTCATAAAACAGGCACAAAAGTTTTATCAGTAAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAA
 481 TTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCACTCAGCTCAATTATCTTCTTAGAAAGAAAGAAAAAGTATGA
 561 ATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTTAAAAGTTTACATAAGTTTTTTTTAACCCCTA
 641 GAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAAACACTGGTGTGCAATTAATTG
 721 GATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTGTCTTATTTTTG
 801 TTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTAT
 881 GTTTTTTCATTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACC
 961 AGTATTTTACTTCAAAAGCCAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGT
1041 TTCTGTAAAACGTGTAATAAGTTGAGTATCTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTC
1121 TTCTTAGTAACTTCTTTCTGTGGCAAAACCACAATTCTTTAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTT
1201 GTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGTAAATATTTATATTCCTTGAAAGCAATTTTTGCCAAGGTAGT
1281 TCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGCATAGATTTTGAAATGTTTTTTTAATGAAAAT
1361 GAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTGAAATAGTAAAATTATAATCGT
1441 TTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGATAAAAAGAGCCT
1521 GCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCAA
1601 AATAATGCTGTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAG
1681 TATTTTCATGATATTAGAACAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTT
1761 ACACTCTGCCTATTCATTGATATATGATATTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAAT
1841 TACATACAAATTGATTGGCTTATCACAAAAATCATTTCATCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTC
1921 TTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCATTTGGTCCAAATAATATTTTATTTGTATGGGTATCTTCTAAG
2001 ACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCAAATGTTATGGGTTCTTACCCAAAGAGTCAAA
2081 AACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCATGCATCTAATCTAATAGTCCTC
2161 TTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTAATTTTAGATCA
2241 GTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTTG
2321 AATGTTATTTACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGT
2401 TTCTAGGATTTATGACCTTATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAA
2481 TAATTATTCACATGTGCATTTTCTTTTTAGCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGC
2561 CCAGGACATGTAAAAAAAAAAAAAAAACAACAACAATAAATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTT
2641 ATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCACTTATAAAGGTACAGTGTACTCTTTGTCACAGCTCAGTTGGT
2721 AACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTAATATTCATGCTTTTGTGCCTTTAAGAAAATA
2801 TTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTGTCATAAAAGGGTCATTTCTGT
2881 GTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCTATTTACCTATT
2961 CTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTTT
3041 TGGCTGTCACCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTT
3121 AAGAAAACAAATGTATAAAATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTG
3201 ATGATGGCATTATTGATAAGCCATACATGAGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAG
3281 ATTTATATCAAATTTTCCAATTTGAACCAGTGGGGAAAATCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTT
3361 ATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAACCTGCCATTATGTAATTTGGTTTCATTTTATTCTACCTGTTG
3441 TGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGTTTATTTTTGTTAGTTTTTAATTGAAGATGGA
3521 CTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCCACGTGAAACCCATGACAAAAT
3601 GAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTTACAGTATCAAA
3681 ATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCACT
3761 TTTTAGCATGCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCA
3841 GTTTTGTGTGATAGAATAAAAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACA
3921 GTAAATGTACAGATAGTTATAGGCCACTGTTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTG
4001 TTTGCAGAAAGAAAAGAATTTTTCTAATAATCTGTAAAATTATGCTAACTTCTACAAGTAGGCTTCTAAATAAAATTTTT
4081 AAAAAGAGCAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugccgaucaccuggucCACUUCa 5'
                          |||||| 
Target 5' gtatccttaggtttctGTGAAGa 3'
 1553 - 1575 120.00 -8.90
2 
miRNA  3' ugccGAUCACCU-GGUCCACUUca 5'
              :|||  || ||| |||||  
Target 5' atatTTAGAAGAGCCACGTGAAac 3'
 3565 - 3588 115.00 -9.30
3 
miRNA  3' ugccGAUCACCUG-GUCCACUUca 5'
              :| || ||: ||||| ||  
Target 5' aataTTTGTAGATGCAGGTAAAta 3'
 647 - 670 111.00 -6.23
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN32053677 29 COSMIC
COSN30457556 43 COSMIC
COSN31604430 98 COSMIC
COSN1152114 104 COSMIC
COSN28874542 105 COSMIC
COSN13418957 144 COSMIC
COSN31527100 145 COSMIC
COSN22571838 255 COSMIC
COSN19586219 570 COSMIC
COSN8586706 572 COSMIC
COSN31583918 592 COSMIC
COSN31489895 767 COSMIC
COSN1585491 812 COSMIC
COSN31491001 843 COSMIC
COSN31481650 845 COSMIC
COSN1585490 859 COSMIC
COSN20092612 1154 COSMIC
COSN1585489 1263 COSMIC
COSN5327923 1602 COSMIC
COSN31566836 1741 COSMIC
COSN31567457 1876 COSMIC
COSN29206402 1945 COSMIC
COSN31534429 2121 COSMIC
COSN6617432 2125 COSMIC
COSN31484812 2201 COSMIC
COSN5327922 2522 COSMIC
COSN20109872 2572 COSMIC
COSN30545322 2585 COSMIC
COSN31565398 2661 COSMIC
COSN8586705 2735 COSMIC
COSN21813064 2765 COSMIC
COSN8586704 3344 COSMIC
COSN26643212 3431 COSMIC
COSN26301126 3799 COSMIC
COSN31515481 3802 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs979177182 4 dbSNP
rs372780726 7 dbSNP
rs887927600 10 dbSNP
rs1439177654 13 dbSNP
rs550059293 14 dbSNP
rs369484524 16 dbSNP
rs1468505837 17 dbSNP
rs1274375549 18 dbSNP
rs760150771 20 dbSNP
rs1027806996 24 dbSNP
rs775547771 29 dbSNP
rs1363824818 32 dbSNP
rs1421393576 40 dbSNP
rs771890972 42 dbSNP
rs1337759575 44 dbSNP
rs745743929 45 dbSNP
rs775839526 46 dbSNP
rs1395286958 49 dbSNP
rs1360934859 63 dbSNP
rs1174223340 66 dbSNP
rs543544015 72 dbSNP
rs1430064015 73 dbSNP
rs1041027070 78 dbSNP
rs944687996 81 dbSNP
rs889152617 82 dbSNP
rs565274912 90 dbSNP
rs745530573 92 dbSNP
rs1265561384 95 dbSNP
rs1287362167 97 dbSNP
rs187324650 98 dbSNP
rs1015153692 99 dbSNP
rs1277024363 100 dbSNP
rs1202702713 104 dbSNP
rs1258751001 106 dbSNP
rs1005120449 111 dbSNP
rs1183250715 112 dbSNP
rs1383403597 112 dbSNP
rs1424575510 112 dbSNP
rs887974573 113 dbSNP
rs1278136713 115 dbSNP
rs1049251491 118 dbSNP
rs1159401675 121 dbSNP
rs528579695 126 dbSNP
rs574444447 128 dbSNP
rs1304326193 129 dbSNP
rs1402667631 132 dbSNP
rs559822137 137 dbSNP
rs989972907 144 dbSNP
rs1378737086 147 dbSNP
rs183033106 152 dbSNP
rs1237566228 154 dbSNP
rs924513829 154 dbSNP
rs1258085834 165 dbSNP
rs944694307 177 dbSNP
rs1446894809 182 dbSNP
rs1203200267 184 dbSNP
rs374781283 186 dbSNP
rs1459307876 196 dbSNP
rs745978068 204 dbSNP
rs574145394 213 dbSNP
rs912486627 216 dbSNP
rs1022625949 218 dbSNP
rs991185141 219 dbSNP
rs557284352 222 dbSNP
rs1027377038 223 dbSNP
rs1334509922 228 dbSNP
rs1401997159 234 dbSNP
rs993641268 235 dbSNP
rs1297067755 237 dbSNP
rs1052324055 242 dbSNP
rs1370570637 245 dbSNP
rs897994629 251 dbSNP
rs776394985 255 dbSNP
rs1019183070 256 dbSNP
rs1324973988 258 dbSNP
rs1223271016 265 dbSNP
rs1470126234 267 dbSNP
rs1261702054 275 dbSNP
rs1320218814 279 dbSNP
rs146471534 283 dbSNP
rs1232314445 286 dbSNP
rs979198261 289 dbSNP
rs889104902 290 dbSNP
rs770317002 294 dbSNP
rs1480096446 295 dbSNP
rs1421807111 300 dbSNP
rs746596054 303 dbSNP
rs946713703 307 dbSNP
rs1465775305 309 dbSNP
rs1169325750 318 dbSNP
rs1352198158 327 dbSNP
rs1472632437 330 dbSNP
rs578028700 345 dbSNP
rs1346675397 347 dbSNP
rs1235952729 354 dbSNP
rs1404911227 357 dbSNP
rs916305630 366 dbSNP
rs1052951495 367 dbSNP
rs1215316753 369 dbSNP
rs777839470 371 dbSNP
rs934478703 373 dbSNP
rs73383530 375 dbSNP
rs960428617 377 dbSNP
rs1490155155 378 dbSNP
rs1197217405 381 dbSNP
rs915840713 384 dbSNP
rs1197346736 396 dbSNP
rs1319357801 400 dbSNP
rs1185786703 403 dbSNP
rs1014990584 406 dbSNP
rs1416934648 418 dbSNP
rs983738458 422 dbSNP
rs952271085 436 dbSNP
rs1027827316 438 dbSNP
rs372380078 439 dbSNP
rs1364428815 443 dbSNP
rs1424515658 462 dbSNP
rs951716597 474 dbSNP
rs1363080632 476 dbSNP
rs141192462 487 dbSNP
rs370888347 487 dbSNP
rs74103404 489 dbSNP
rs900596752 493 dbSNP
rs1230273481 508 dbSNP
rs1376432812 514 dbSNP
rs1285606558 517 dbSNP
rs1358835997 527 dbSNP
rs962231975 540 dbSNP
rs544231232 553 dbSNP
rs1375933671 555 dbSNP
rs1447576465 555 dbSNP
rs1214784551 558 dbSNP
rs1019004231 563 dbSNP
rs1009377651 565 dbSNP
rs891821016 568 dbSNP
rs747882754 569 dbSNP
rs1384004717 575 dbSNP
rs565619494 578 dbSNP
rs1329203646 580 dbSNP
rs1019552171 581 dbSNP
rs555413930 587 dbSNP
rs903748507 589 dbSNP
rs1043555325 590 dbSNP
rs1356353504 592 dbSNP
rs1343825391 598 dbSNP
rs1450399136 603 dbSNP
rs947890814 610 dbSNP
rs1029268749 614 dbSNP
rs1300756016 619 dbSNP
rs756307912 620 dbSNP
rs1243859625 628 dbSNP
rs28394250 632 dbSNP
rs1404855250 633 dbSNP
rs1351276306 635 dbSNP
rs991952202 644 dbSNP
rs939090289 646 dbSNP
rs1443930662 647 dbSNP
rs1445586517 654 dbSNP
rs1238005493 661 dbSNP
rs907580657 667 dbSNP
rs1481944665 670 dbSNP
rs902998501 672 dbSNP
rs983075510 681 dbSNP
rs952281975 682 dbSNP
rs74103403 694 dbSNP
rs767851610 696 dbSNP
rs1471159145 708 dbSNP
rs1177679389 713 dbSNP
rs1405597056 718 dbSNP
rs1450782298 720 dbSNP
rs964929492 739 dbSNP
rs757274914 747 dbSNP
rs930301416 754 dbSNP
rs1019516056 763 dbSNP
rs1441302591 764 dbSNP
rs1277696219 766 dbSNP
rs1347107088 769 dbSNP
rs1223873788 772 dbSNP
rs920292108 777 dbSNP
rs971819377 788 dbSNP
rs1246326674 810 dbSNP
rs1352701905 814 dbSNP
rs1319404785 815 dbSNP
rs569783923 822 dbSNP
rs188435980 831 dbSNP
rs1031642591 841 dbSNP
rs1481735835 842 dbSNP
rs751655823 848 dbSNP
rs1373895623 858 dbSNP
rs1429068167 874 dbSNP
rs903800707 875 dbSNP
rs987617143 878 dbSNP
rs764391051 879 dbSNP
rs1397561788 881 dbSNP
rs1409435235 887 dbSNP
rs1326986412 903 dbSNP
rs1347286524 912 dbSNP
rs1405517953 913 dbSNP
rs554281888 918 dbSNP
rs1343426335 919 dbSNP
rs1292889905 920 dbSNP
rs1220020361 928 dbSNP
rs1043648724 938 dbSNP
rs947953706 948 dbSNP
rs533253748 954 dbSNP
rs1011197321 955 dbSNP
rs758857696 958 dbSNP
rs536010338 979 dbSNP
rs1056698956 985 dbSNP
rs1200813410 989 dbSNP
rs1268539222 990 dbSNP
rs1479656629 1005 dbSNP
rs939116887 1013 dbSNP
rs1031444771 1037 dbSNP
rs907589241 1040 dbSNP
rs145319969 1045 dbSNP
rs551775554 1047 dbSNP
rs752963878 1051 dbSNP
rs1047440779 1052 dbSNP
rs999545328 1057 dbSNP
rs930271274 1058 dbSNP
rs1174674899 1064 dbSNP
rs1409288273 1067 dbSNP
rs1425160657 1073 dbSNP
rs920237792 1073 dbSNP
rs1191152041 1074 dbSNP
rs1363712887 1079 dbSNP
rs1383694176 1082 dbSNP
rs906586465 1089 dbSNP
rs1025061434 1095 dbSNP
rs1224831208 1096 dbSNP
rs975049291 1100 dbSNP
rs1014009015 1107 dbSNP
rs73383529 1114 dbSNP
rs1222770353 1115 dbSNP
rs1055634159 1126 dbSNP
rs898817430 1126 dbSNP
rs930584226 1126 dbSNP
rs1262902951 1131 dbSNP
rs1487722003 1135 dbSNP
rs912100695 1140 dbSNP
rs1283457660 1142 dbSNP
rs1191321594 1154 dbSNP
rs1036411271 1157 dbSNP
rs1445311409 1167 dbSNP
rs1163076956 1168 dbSNP
rs1240860362 1169 dbSNP
rs988013845 1170 dbSNP
rs1455321991 1176 dbSNP
rs1289192431 1178 dbSNP
rs1384006071 1184 dbSNP
rs956140467 1185 dbSNP
rs1031694862 1186 dbSNP
rs940389042 1187 dbSNP
rs987229438 1188 dbSNP
rs1300468830 1189 dbSNP
rs1241833541 1190 dbSNP
rs559501105 1195 dbSNP
rs539195415 1197 dbSNP
rs777162232 1197 dbSNP
rs922134074 1205 dbSNP
rs1000219943 1209 dbSNP
rs1285349192 1210 dbSNP
rs1245188748 1211 dbSNP
rs543069299 1214 dbSNP
rs1183033376 1220 dbSNP
rs1360067689 1225 dbSNP
rs534889302 1228 dbSNP
rs867304068 1228 dbSNP
rs759901225 1237 dbSNP
rs978458337 1238 dbSNP
rs1451336727 1242 dbSNP
rs970761426 1264 dbSNP
rs1025007071 1267 dbSNP
rs1451498108 1275 dbSNP
rs1022915390 1279 dbSNP
rs1374895106 1281 dbSNP
rs1012205496 1295 dbSNP
rs894292403 1297 dbSNP
rs1034173607 1299 dbSNP
rs1316903110 1309 dbSNP
rs994695302 1311 dbSNP
rs1432017307 1316 dbSNP
rs1324490956 1321 dbSNP
rs895016845 1323 dbSNP
rs1056307274 1335 dbSNP
rs747430162 1345 dbSNP
rs1177907719 1349 dbSNP
rs1432095295 1352 dbSNP
rs1003759094 1361 dbSNP
rs529373488 1362 dbSNP
rs899055928 1364 dbSNP
rs563539917 1365 dbSNP
rs543650299 1369 dbSNP
rs1468911088 1373 dbSNP
rs1173818822 1376 dbSNP
rs886207215 1379 dbSNP
rs150066264 1380 dbSNP
rs1206571107 1389 dbSNP
rs183938357 1400 dbSNP
rs890162519 1402 dbSNP
rs920290275 1411 dbSNP
rs199587946 1415 dbSNP
rs1285533797 1417 dbSNP
rs1039105416 1418 dbSNP
rs1346557940 1422 dbSNP
rs1223067879 1423 dbSNP
rs763484920 1433 dbSNP
rs753011811 1438 dbSNP
rs191966849 1439 dbSNP
rs1283864544 1443 dbSNP
rs571966245 1450 dbSNP
rs936855618 1457 dbSNP
rs1339973043 1481 dbSNP
rs1224643928 1484 dbSNP
rs1293658573 1486 dbSNP
rs1479985094 1501 dbSNP
rs912103655 1517 dbSNP
rs1197085872 1520 dbSNP
rs1421178393 1523 dbSNP
rs1384180970 1524 dbSNP
rs1428791296 1529 dbSNP
rs555070174 1529 dbSNP
rs185909319 1531 dbSNP
rs759985719 1538 dbSNP
rs971131332 1555 dbSNP
rs776143055 1556 dbSNP
rs924769939 1562 dbSNP
rs377652334 1563 dbSNP
rs968771650 1577 dbSNP
rs1464621499 1578 dbSNP
rs556375397 1595 dbSNP
rs777182008 1596 dbSNP
rs1420902831 1605 dbSNP
rs760044142 1617 dbSNP
rs1194857318 1620 dbSNP
rs1022969213 1625 dbSNP
rs1027047283 1631 dbSNP
rs772851253 1635 dbSNP
rs539670036 1647 dbSNP
rs1340142365 1654 dbSNP
rs1248347712 1664 dbSNP
rs1292392736 1666 dbSNP
rs1490180423 1672 dbSNP
rs1219072573 1677 dbSNP
rs117011380 1690 dbSNP
rs1485964075 1691 dbSNP
rs1255053645 1692 dbSNP
rs1185590182 1693 dbSNP
rs1387719673 1693 dbSNP
rs12228572 1696 dbSNP
rs1035325683 1702 dbSNP
rs1179841890 1711 dbSNP
rs1163714582 1712 dbSNP
rs1386365954 1713 dbSNP
rs1462500725 1715 dbSNP
rs1424618304 1716 dbSNP
rs1015250494 1720 dbSNP
rs1263633900 1730 dbSNP
rs1197977101 1737 dbSNP
rs1431667641 1742 dbSNP
rs1317348002 1748 dbSNP
rs1363362106 1762 dbSNP
rs1003442458 1775 dbSNP
rs1004841573 1783 dbSNP
rs1249762218 1785 dbSNP
rs140596796 1787 dbSNP
rs1047585149 1792 dbSNP
rs1051458711 1803 dbSNP
rs1312311636 1807 dbSNP
rs994626381 1813 dbSNP
rs898874243 1815 dbSNP
rs1038711914 1818 dbSNP
rs900213095 1821 dbSNP
rs943006973 1822 dbSNP
rs1446772242 1823 dbSNP
rs533855954 1824 dbSNP
rs936826520 1825 dbSNP
rs1169073515 1830 dbSNP
rs566019479 1831 dbSNP
rs1161994054 1834 dbSNP
rs1401648159 1835 dbSNP
rs1410879587 1835 dbSNP
rs368068282 1839 dbSNP
rs1386697362 1843 dbSNP
rs934907256 1844 dbSNP
rs924822139 1848 dbSNP
rs1454801097 1850 dbSNP
rs1043012211 1855 dbSNP
rs1445652803 1863 dbSNP
rs949688271 1866 dbSNP
rs1374049155 1868 dbSNP
rs918180295 1877 dbSNP
rs1266038922 1878 dbSNP
rs1325198765 1888 dbSNP
rs1203910739 1891 dbSNP
rs1162292516 1895 dbSNP
rs1440184624 1903 dbSNP
rs978861744 1905 dbSNP
rs1446193974 1916 dbSNP
rs1235072568 1918 dbSNP
rs947483248 1942 dbSNP
rs1243577764 1943 dbSNP
rs375418212 1958 dbSNP
rs549159252 1964 dbSNP
rs1429247213 1971 dbSNP
rs748116081 1972 dbSNP
rs1197584695 1987 dbSNP
rs919979987 1989 dbSNP
rs796902029 1993 dbSNP
rs974221892 1998 dbSNP
rs1481018650 2007 dbSNP
rs1412826727 2009 dbSNP
rs1265051785 2010 dbSNP
rs1331016701 2011 dbSNP
rs1255522592 2013 dbSNP
rs1354993129 2016 dbSNP
rs372018425 2018 dbSNP
rs1362026683 2024 dbSNP
rs991523219 2030 dbSNP
rs779038624 2031 dbSNP
rs1316250752 2033 dbSNP
rs1342490175 2036 dbSNP
rs878861179 2038 dbSNP
rs768299981 2045 dbSNP
rs529382480 2054 dbSNP
rs1239881605 2057 dbSNP
rs1205079342 2059 dbSNP
rs1035682025 2066 dbSNP
rs1334445409 2083 dbSNP
rs1200680349 2101 dbSNP
rs1377247045 2101 dbSNP
rs1014784276 2109 dbSNP
rs1169687596 2120 dbSNP
rs982056964 2121 dbSNP
rs1391420983 2122 dbSNP
rs1428967968 2125 dbSNP
rs1389432725 2140 dbSNP
rs749169833 2152 dbSNP
rs1405297396 2156 dbSNP
rs1322706771 2158 dbSNP
rs1300877486 2166 dbSNP
rs1328947541 2170 dbSNP
rs1426222153 2175 dbSNP
rs1385483126 2178 dbSNP
rs954583773 2180 dbSNP
rs1030254480 2190 dbSNP
rs1225619139 2191 dbSNP
rs563475293 2194 dbSNP
rs1365430548 2197 dbSNP
rs950607449 2200 dbSNP
rs1182487182 2205 dbSNP
rs143988864 2207 dbSNP
rs1267148651 2219 dbSNP
rs1450022072 2230 dbSNP
rs368399560 2236 dbSNP
rs74102402 2238 dbSNP
rs1220534723 2244 dbSNP
rs533323027 2248 dbSNP
rs1448936815 2249 dbSNP
rs1292797364 2254 dbSNP
rs898935282 2255 dbSNP
rs1166838715 2263 dbSNP
rs1386991942 2277 dbSNP
rs1000641553 2278 dbSNP
rs1017796597 2286 dbSNP
rs774036512 2295 dbSNP
rs538493720 2304 dbSNP
rs1216282121 2308 dbSNP
rs564356577 2312 dbSNP
rs902665678 2322 dbSNP
rs1349024061 2325 dbSNP
rs890152827 2327 dbSNP
rs1364093435 2336 dbSNP
rs1051435339 2337 dbSNP
rs1240444627 2342 dbSNP
rs1316592701 2347 dbSNP
rs757509358 2363 dbSNP
rs903412055 2368 dbSNP
rs1055314020 2369 dbSNP
rs1406261993 2376 dbSNP
rs1365762996 2381 dbSNP
rs938007577 2399 dbSNP
rs919968791 2401 dbSNP
rs974544556 2403 dbSNP
rs1386931041 2414 dbSNP
rs961513025 2424 dbSNP
rs569518791 2432 dbSNP
rs1477697112 2436 dbSNP
rs1375863443 2439 dbSNP
rs1164008873 2440 dbSNP
rs1366704778 2444 dbSNP
rs908634453 2449 dbSNP
rs1158969566 2451 dbSNP
rs1043218347 2459 dbSNP
rs1455333697 2461 dbSNP
rs1197291226 2462 dbSNP
rs947533487 2469 dbSNP
rs916063456 2481 dbSNP
rs992011588 2487 dbSNP
rs1236278860 2491 dbSNP
rs938769640 2492 dbSNP
rs375458301 2493 dbSNP
rs1286849802 2502 dbSNP
rs982740033 2506 dbSNP
rs1269186383 2513 dbSNP
rs1344856224 2515 dbSNP
rs1265019872 2519 dbSNP
rs954533822 2531 dbSNP
rs1181422542 2550 dbSNP
rs1224774208 2567 dbSNP
rs1420853139 2568 dbSNP
rs1345645479 2569 dbSNP
rs74102401 2570 dbSNP
rs1428285459 2571 dbSNP
rs1410966786 2572 dbSNP
rs1471374911 2572 dbSNP
rs1178130524 2573 dbSNP
rs1327978549 2577 dbSNP
rs1318649855 2578 dbSNP
rs1030244530 2581 dbSNP
rs1413711455 2582 dbSNP
rs201592030 2583 dbSNP
rs200454253 2584 dbSNP
rs10777951 2585 dbSNP
rs201340784 2586 dbSNP
rs78008233 2586 dbSNP
rs1470978484 2587 dbSNP
rs116833024 2588 dbSNP
rs1339784319 2588 dbSNP
rs1481549984 2588 dbSNP
rs34398462 2588 dbSNP
rs398020187 2588 dbSNP
rs1251067555 2589 dbSNP
rs1430127199 2589 dbSNP
rs1186130320 2590 dbSNP
rs1201373373 2591 dbSNP
rs964356454 2593 dbSNP
rs950618433 2594 dbSNP
rs1244060897 2608 dbSNP
rs1194289503 2615 dbSNP
rs768244973 2625 dbSNP
rs1173293704 2627 dbSNP
rs1374299098 2629 dbSNP
rs1442241057 2634 dbSNP
rs1241807283 2635 dbSNP
rs1370551262 2640 dbSNP
rs1408353201 2647 dbSNP
rs1026214864 2649 dbSNP
rs1305388433 2653 dbSNP
rs1368511907 2654 dbSNP
rs1032034068 2661 dbSNP
rs1299215228 2662 dbSNP
rs1323611023 2668 dbSNP
rs180988634 2683 dbSNP
rs902235195 2693 dbSNP
rs1482061857 2696 dbSNP
rs1276743847 2706 dbSNP
rs1247099866 2711 dbSNP
rs1487916475 2714 dbSNP
rs12229382 2715 dbSNP
rs1263480965 2718 dbSNP
rs973299173 2722 dbSNP
rs963574972 2724 dbSNP
rs1428403873 2726 dbSNP
rs1270431393 2733 dbSNP
rs1446965516 2746 dbSNP
rs1017431470 2749 dbSNP
rs1350835357 2758 dbSNP
rs576063903 2759 dbSNP
rs3825176 2766 dbSNP
rs890173671 2773 dbSNP
rs1029962415 2786 dbSNP
rs1364403336 2793 dbSNP
rs1453355417 2799 dbSNP
rs115510313 2801 dbSNP
rs1296994629 2807 dbSNP
rs1055304192 2817 dbSNP
rs1248086982 2824 dbSNP
rs1169744317 2831 dbSNP
rs1320874886 2831 dbSNP
rs1408302508 2834 dbSNP
rs1219189198 2835 dbSNP
rs143238067 2837 dbSNP
rs1321002898 2841 dbSNP
rs938289571 2845 dbSNP
rs911742021 2871 dbSNP
rs148667996 2873 dbSNP
rs1245698520 2881 dbSNP
rs1448127193 2890 dbSNP
rs1444378755 2892 dbSNP
rs1415246359 2897 dbSNP
rs534093327 2900 dbSNP
rs1163182168 2903 dbSNP
rs1347136897 2905 dbSNP
rs1457996522 2908 dbSNP
rs1319895857 2915 dbSNP
rs775077732 2919 dbSNP
rs1038346150 2929 dbSNP
rs190085331 2931 dbSNP
rs1378401487 2937 dbSNP
rs771758555 2937 dbSNP
rs1226377238 2938 dbSNP
rs549343897 2942 dbSNP
rs1201762796 2944 dbSNP
rs1439074930 2950 dbSNP
rs940036103 2956 dbSNP
rs758522923 2958 dbSNP
rs1462268352 2967 dbSNP
rs908589470 2969 dbSNP
rs1316977409 2978 dbSNP
rs1238538751 2986 dbSNP
rs986916231 2994 dbSNP
rs1375982131 3000 dbSNP
rs753171314 3002 dbSNP
rs933137897 3007 dbSNP
rs923122944 3013 dbSNP
rs1440078873 3023 dbSNP
rs367914667 3024 dbSNP
rs535509966 3040 dbSNP
rs144020089 3043 dbSNP
rs765838489 3045 dbSNP
rs1383624608 3046 dbSNP
rs1358455682 3051 dbSNP
rs1355706123 3052 dbSNP
rs549829429 3059 dbSNP
rs1445770935 3061 dbSNP
rs1281000561 3066 dbSNP
rs964592895 3070 dbSNP
rs1227618596 3071 dbSNP
rs1286039470 3074 dbSNP
rs539563234 3076 dbSNP
rs1219259766 3091 dbSNP
rs1277341076 3092 dbSNP
rs1307026094 3094 dbSNP
rs1442283490 3105 dbSNP
rs1208660258 3106 dbSNP
rs1445638776 3114 dbSNP
rs1483583436 3117 dbSNP
rs1407841511 3119 dbSNP
rs979080162 3120 dbSNP
rs966788120 3125 dbSNP
rs1173189822 3133 dbSNP
rs1424549943 3134 dbSNP
rs1412626428 3135 dbSNP
rs769621575 3137 dbSNP
rs1309758194 3146 dbSNP
rs1371134764 3174 dbSNP
rs1020696714 3182 dbSNP
rs1470866545 3187 dbSNP
rs1233008408 3188 dbSNP
rs778177398 3190 dbSNP
rs1305983593 3193 dbSNP
rs1013329555 3197 dbSNP
rs896642980 3203 dbSNP
rs1273672771 3205 dbSNP
rs1342247451 3207 dbSNP
rs1215885691 3208 dbSNP
rs1277356332 3209 dbSNP
rs1343558695 3213 dbSNP
rs533253190 3221 dbSNP
rs1204823944 3223 dbSNP
rs1250104374 3227 dbSNP
rs1033838357 3228 dbSNP
rs1489680940 3239 dbSNP
rs745861911 3242 dbSNP
rs570647374 3245 dbSNP
rs1170621306 3247 dbSNP
rs1390663432 3252 dbSNP
rs898725821 3253 dbSNP
rs1039030693 3261 dbSNP
rs1352769304 3263 dbSNP
rs940028684 3274 dbSNP
rs759804659 3284 dbSNP
rs564335951 3287 dbSNP
rs1329033885 3299 dbSNP
rs1225451772 3304 dbSNP
rs756474327 3308 dbSNP
rs1051162493 3310 dbSNP
rs1272854833 3313 dbSNP
rs1358889656 3315 dbSNP
rs1210879071 3324 dbSNP
rs1289406318 3332 dbSNP
rs1450110655 3335 dbSNP
rs1190553624 3339 dbSNP
rs1375620029 3345 dbSNP
rs1448735568 3346 dbSNP
rs934092957 3350 dbSNP
rs921360438 3356 dbSNP
rs1370192270 3358 dbSNP
rs74102400 3366 dbSNP
rs527970289 3367 dbSNP
rs1162483366 3369 dbSNP
rs1388067082 3372 dbSNP
rs1404428690 3392 dbSNP
rs781248489 3395 dbSNP
rs1305217631 3399 dbSNP
rs1425652981 3402 dbSNP
rs1345017651 3417 dbSNP
rs1310431602 3432 dbSNP
rs1294051100 3433 dbSNP
rs1157535450 3434 dbSNP
rs755145258 3437 dbSNP
rs1245928642 3438 dbSNP
rs1403020868 3445 dbSNP
rs1354431662 3453 dbSNP
rs754241662 3455 dbSNP
rs1269074429 3456 dbSNP
rs979793541 3470 dbSNP
rs1206949596 3475 dbSNP
rs1479181479 3488 dbSNP
rs966402060 3493 dbSNP
rs1046209 3498 dbSNP
rs757465451 3501 dbSNP
rs913584556 3505 dbSNP
rs1199760231 3507 dbSNP
rs1485414585 3511 dbSNP
rs374889336 3520 dbSNP
rs1258814321 3527 dbSNP
rs991856670 3532 dbSNP
rs1387536348 3534 dbSNP
rs960416666 3544 dbSNP
rs1304105682 3558 dbSNP
rs185592217 3562 dbSNP
rs1397130468 3563 dbSNP
rs1033408222 3579 dbSNP
rs1217687112 3581 dbSNP
rs765879479 3582 dbSNP
rs1230696479 3588 dbSNP
rs1289188275 3600 dbSNP
rs535825983 3620 dbSNP
rs1002290376 3630 dbSNP
rs963237807 3637 dbSNP
rs760432071 3639 dbSNP
rs1004894405 3642 dbSNP
rs887101884 3646 dbSNP
rs1285401587 3651 dbSNP
rs1199817164 3655 dbSNP
rs1405838726 3657 dbSNP
rs1483909020 3657 dbSNP
rs1182677914 3670 dbSNP
rs1471425421 3675 dbSNP
rs1361692240 3680 dbSNP
rs772796146 3698 dbSNP
rs1287415567 3699 dbSNP
rs1462975442 3702 dbSNP
rs1051061940 3704 dbSNP
rs1465159804 3708 dbSNP
rs1172501430 3709 dbSNP
rs1374216942 3718 dbSNP
rs1412041998 3733 dbSNP
rs1309040156 3737 dbSNP
rs998202969 3738 dbSNP
rs1389893165 3747 dbSNP
rs1346255318 3749 dbSNP
rs899877644 3755 dbSNP
rs1232708725 3757 dbSNP
rs1312776893 3761 dbSNP
rs1278058617 3763 dbSNP
rs1344288934 3767 dbSNP
rs1205563325 3770 dbSNP
rs149543591 3775 dbSNP
rs1479423020 3782 dbSNP
rs943210793 3787 dbSNP
rs374931504 3791 dbSNP
rs1432060276 3795 dbSNP
rs1173405619 3810 dbSNP
rs181491878 3811 dbSNP
rs1430867977 3815 dbSNP
rs1043634133 3824 dbSNP
rs1169546509 3826 dbSNP
rs1427491522 3831 dbSNP
rs945317945 3832 dbSNP
rs1368616717 3837 dbSNP
rs1301364759 3839 dbSNP
rs190117180 3846 dbSNP
rs913834428 3848 dbSNP
rs1273909985 3859 dbSNP
rs991762446 3871 dbSNP
rs1223547342 3875 dbSNP
rs1265642895 3896 dbSNP
rs1487967895 3897 dbSNP
rs1191160920 3898 dbSNP
rs1249351133 3902 dbSNP
rs1189760813 3908 dbSNP
rs536364871 3909 dbSNP
rs545870400 3918 dbSNP
rs1427073670 3919 dbSNP
rs761444699 3923 dbSNP
rs1242417036 3926 dbSNP
rs926341724 3928 dbSNP
rs980967521 3933 dbSNP
rs1435998763 3937 dbSNP
rs1296742821 3943 dbSNP
rs1359843361 3945 dbSNP
rs1229771696 3952 dbSNP
rs1313201967 3958 dbSNP
rs577061069 3959 dbSNP
rs1211453119 3964 dbSNP
rs1269691895 3974 dbSNP
rs1464953065 3976 dbSNP
rs1207595859 3977 dbSNP
rs1017547973 3978 dbSNP
rs185267075 3981 dbSNP
rs1307077982 3983 dbSNP
rs951691343 3991 dbSNP
rs768655034 3994 dbSNP
rs1029920806 3995 dbSNP
rs547504807 4001 dbSNP
rs1363155575 4002 dbSNP
rs1336637970 4005 dbSNP
rs1343325377 4016 dbSNP
rs1450130997 4019 dbSNP
rs1303151610 4030 dbSNP
rs748972201 4033 dbSNP
rs1451184951 4036 dbSNP
rs55768668 4036 dbSNP
rs1289799572 4043 dbSNP
rs540091547 4045 dbSNP
rs1329490947 4049 dbSNP
rs1227191301 4050 dbSNP
rs527974300 4054 dbSNP
rs1281561617 4063 dbSNP
rs1445721930 4073 dbSNP
rs1212845135 4080 dbSNP
rs1408948705 4081 dbSNP
rs1485531922 4089 dbSNP
rs574655581 4089 dbSNP
rs758628639 4093 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions islets
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO. ...

- Kameswaran V; Bramswig NC; McKenna LB; Penn et al., 2014, Cell metabolism.

Article - Kameswaran V; Bramswig NC; McKenna LB; Penn et al.
- Cell metabolism, 2014
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing beta cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the pathogenesis of human T2DM, we sequenced the small RNAs of human islets from diabetic and nondiabetic organ donors. We identified a cluster of microRNAs in an imprinted locus on human chromosome 14q32 that is highly and specifically expressed in human beta cells and dramatically downregulated in islets from T2DM organ donors. The downregulation of this locus strongly correlates with hypermethylation of its promoter. Using HITS-CLIP for the essential RISC-component Argonaute, we identified disease-relevant targets of the chromosome 14q32 microRNAs, such as IAPP and TP53INP1, that cause increased beta cell apoptosis upon overexpression in human islets. Our results support a role for microRNAs and their epigenetic control by DNA methylation in the pathogenesis of T2DM.
LinkOut: [PMID: 24374217]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
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138 hsa-miR-412-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT005780 ACVR1C activin A receptor type 1C 1 1
MIRT062013 YOD1 YOD1 deubiquitinase 2 2
MIRT345112 ATXN7L3 ataxin 7 like 3 2 2
MIRT383735 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT396956 CELF1 CUGBP Elav-like family member 1 2 2
MIRT439280 XIAP X-linked inhibitor of apoptosis 1 1
MIRT439313 VAT1 vesicle amine transport 1 1 1
MIRT439375 TUBA1A tubulin alpha 1a 1 1
MIRT439418 TMOD1 tropomodulin 1 1 1
MIRT439503 SURF4 surfeit 4 1 1
MIRT439563 SON SON DNA binding protein 1 1
MIRT439598 SLC3A2 solute carrier family 3 member 2 1 1
MIRT439670 SETD1B SET domain containing 1B 1 1
MIRT439767 RMND5A required for meiotic nuclear division 5 homolog A 1 1
MIRT439922 PPL periplakin 1 1
MIRT439947 PLEKHA6 pleckstrin homology domain containing A6 1 1
MIRT439952 PLCB4 phospholipase C beta 4 1 1
MIRT439961 PKD1 polycystin 1, transient receptor potential channel interacting 1 1
MIRT440005 PEG3 paternally expressed 3 1 1
MIRT440061 OSBPL8 oxysterol binding protein like 8 1 1
MIRT440166 MYH14 myosin heavy chain 14 1 1
MIRT440276 MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1 1
MIRT440437 IPO13 importin 13 1 1
MIRT440441 INTS3 integrator complex subunit 3 1 1
MIRT440448 INS insulin 1 1
MIRT440461 IGF2R insulin like growth factor 2 receptor 1 1
MIRT440472 IARS isoleucyl-tRNA synthetase 1 1
MIRT440530 GUCY1A3 guanylate cyclase 1 soluble subunit alpha 1 1
MIRT440542 GOLGA2 golgin A2 1 1
MIRT440569 GIGYF1 GRB10 interacting GYF protein 1 1 1
MIRT440608 FTSJD2 cap methyltransferase 1 1 1
MIRT440750 EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1 1
MIRT440781 DOT1L DOT1 like histone lysine methyltransferase 1 1
MIRT440804 DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 1 1
MIRT440867 CSDE1 cold shock domain containing E1 1 1
MIRT440890 CPEB4 cytoplasmic polyadenylation element binding protein 4 1 1
MIRT440917 COL1A1 collagen type I alpha 1 chain 1 1
MIRT440967 CDH22 cadherin 22 1 1
MIRT440968 CDH2 cadherin 2 1 1
MIRT441024 CALR calreticulin 1 1
MIRT441278 ACTB actin beta 1 1
MIRT448421 TNFAIP3 TNF alpha induced protein 3 2 2
MIRT462833 BCL3 B-cell CLL/lymphoma 3 2 2
MIRT465062 TSR1 TSR1, ribosome maturation factor 2 2
MIRT476050 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT485318 MZT1 mitotic spindle organizing protein 1 2 4
MIRT493584 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 6
MIRT494567 BAK1 BCL2 antagonist/killer 1 2 2
MIRT497393 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT503250 ZNF257 zinc finger protein 257 2 10
MIRT503656 ZNF138 zinc finger protein 138 2 10
MIRT505882 RNF219 ring finger protein 219 2 2
MIRT507525 DSTN destrin, actin depolymerizing factor 2 4
MIRT510663 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 4
MIRT514682 ZNF701 zinc finger protein 701 2 4
MIRT515370 ZNF208 zinc finger protein 208 2 6
MIRT525237 KCNJ12 potassium voltage-gated channel subfamily J member 12 2 2
MIRT527963 MTAP methylthioadenosine phosphorylase 2 2
MIRT528482 STAMBPL1 STAM binding protein like 1 2 2
MIRT529909 C1orf64 steroid receptor associated and regulated protein 2 4
MIRT531558 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT532234 KLF2 Kruppel like factor 2 2 4
MIRT532480 HOXA13 homeobox A13 2 2
MIRT535544 P2RY2 purinergic receptor P2Y2 2 2
MIRT547311 NR1D2 nuclear receptor subfamily 1 group D member 2 2 2
MIRT551795 ZNF117 zinc finger protein 117 2 4
MIRT554939 RAP1A RAP1A, member of RAS oncogene family 2 2
MIRT558171 EIF5A2 eukaryotic translation initiation factor 5A2 2 2
MIRT568771 LY6K lymphocyte antigen 6 family member K 2 2
MIRT570766 ZNF99 zinc finger protein 99 2 2
MIRT572405 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT573396 DLC1 DLC1 Rho GTPase activating protein 2 2
MIRT610403 RXRB retinoid X receptor beta 2 2
MIRT610886 SCN8A sodium voltage-gated channel alpha subunit 8 2 2
MIRT611197 TMEM105 transmembrane protein 105 2 2
MIRT611244 ZNF550 zinc finger protein 550 2 2
MIRT615669 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 4
MIRT617974 DOCK4 dedicator of cytokinesis 4 2 2
MIRT619150 ZNF326 zinc finger protein 326 2 2
MIRT619608 MKKS McKusick-Kaufman syndrome 2 2
MIRT621053 DGKD diacylglycerol kinase delta 2 2
MIRT623665 HRK harakiri, BCL2 interacting protein 2 2
MIRT624883 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT624939 MARCH2 membrane associated ring-CH-type finger 2 2 2
MIRT634198 TMOD2 tropomodulin 2 2 4
MIRT636727 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT637741 POLR3K RNA polymerase III subunit K 2 2
MIRT638002 ZC3H13 zinc finger CCCH-type containing 13 2 2
MIRT640395 ZNF785 zinc finger protein 785 2 2
MIRT640505 ANTXR1 anthrax toxin receptor 1 2 2
MIRT641293 SLAMF1 signaling lymphocytic activation molecule family member 1 2 2
MIRT641863 STOML1 stomatin like 1 2 2
MIRT642600 C14orf180 chromosome 14 open reading frame 180 2 2
MIRT642895 CASP1 caspase 1 2 2
MIRT643967 FHL2 four and a half LIM domains 2 2 4
MIRT645237 KCTD12 potassium channel tetramerization domain containing 12 2 2
MIRT646621 CENPL centromere protein L 2 2
MIRT648620 CYB561A3 cytochrome b561 family member A3 2 2
MIRT648908 ZNF551 zinc finger protein 551 2 2
MIRT649439 HIBADH 3-hydroxyisobutyrate dehydrogenase 2 2
MIRT650637 LTF lactotransferrin 2 2
MIRT650971 STARD3NL STARD3 N-terminal like 2 2
MIRT651067 ZNF518B zinc finger protein 518B 2 4
MIRT652384 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT653958 SEPN1 selenoprotein N 2 2
MIRT656885 KIF1C kinesin family member 1C 2 2
MIRT657965 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT658080 FOXR2 forkhead box R2 2 2
MIRT662570 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT663089 METTL10 EEF1A lysine methyltransferase 2 2 2
MIRT683705 ZNF195 zinc finger protein 195 2 2
MIRT683835 ZNF682 zinc finger protein 682 2 2
MIRT706811 APOL4 apolipoprotein L4 2 2
MIRT707575 DYNC2LI1 dynein cytoplasmic 2 light intermediate chain 1 2 2
MIRT708606 ZNF260 zinc finger protein 260 2 2
MIRT708859 TMSB4X thymosin beta 4, X-linked 2 2
MIRT709861 PDIK1L PDLIM1 interacting kinase 1 like 2 2
MIRT709987 RBM41 RNA binding motif protein 41 2 2
MIRT710098 KPNA5 karyopherin subunit alpha 5 2 2
MIRT710211 ENAH ENAH, actin regulator 2 2
MIRT710868 B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2 2
MIRT710986 SUSD5 sushi domain containing 5 2 2
MIRT711460 RNF145 ring finger protein 145 2 2
MIRT712302 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT713609 SYTL4 synaptotagmin like 4 2 2
MIRT713789 MAK16 MAK16 homolog 2 2
MIRT715480 MYO9B myosin IXB 2 2
MIRT716328 POU5F1 POU class 5 homeobox 1 2 2
MIRT717252 TMEM246 transmembrane protein 246 2 2
MIRT718077 CLIC5 chloride intracellular channel 5 2 2
MIRT718463 EED embryonic ectoderm development 2 2
MIRT718645 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT718982 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT721078 RPS9 ribosomal protein S9 2 2
MIRT721419 SEC24A SEC24 homolog A, COPII coat complex component 2 2
MIRT721863 CENPJ centromere protein J 2 2
MIRT722492 PNKD paroxysmal nonkinesigenic dyskinesia 2 2
MIRT723391 CALN1 calneuron 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-412 Gemcitabine approved 60750 Northern blot Mz-ChA-1 human cholangiocarcinoma cell lines 16762633 2006 down-regulated
miR-412 Progesterone approved 5994 Microarray Breast cancer 22330642 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-412 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-412 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-412-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-412-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-miR-412-3p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (RKO)
hsa-miR-412-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HCT-116)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-miR-412-3p Doxorubicin 31703 NSC123127 approved sensitive High Anaplastic Thyroid Cancer tissue
hsa-miR-412-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-412-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-412-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM43)
hsa-miR-412-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-412-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-412-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-412-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (Panc1-GR1)
hsa-miR-412-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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