miRTarBase - #MIRT440131


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pre-miRNA Information
pre-miRNA hsa-mir-1185-1   
Genomic Coordinates chr14: 101042977 - 101043062
Synonyms MIRN1185-1, hsa-mir-1185-1, MIR1185-1
Description Homo sapiens miR-1185-1 stem-loop
Comment This sequence was proposed as a miRNA candidate by Berezikov et al by RAKE analysis .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1185-1-3p
Sequence 53| AUAUACAGGGGGAGACUCUUAU |74
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 14 + 101043033 29233923 MiREDiBase
A-to-I 7 14 + 101043035 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs749794228 1 dbSNP
rs369414498 4 dbSNP
rs771096180 5 dbSNP
rs774958411 7 dbSNP
rs1226171972 11 dbSNP
rs1449899083 14 dbSNP
rs761183893 16 dbSNP
rs1380874583 20 dbSNP
rs771625921 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NCOA4   
Synonyms ARA70, ELE1, PTC3, RFG
Description nuclear receptor coactivator 4
Transcript NM_001145260   
Other Transcripts NM_001145261 , NM_001145262 , NM_001145263 , NM_005437   
Expression
Putative miRNA Targets on NCOA4
3'UTR of NCOA4
(miRNA target sites are highlighted)		 
>NCOA4|NM_001145260|3'UTR
   1 TAGTTTATATACCTACCTCGAAGATGTGAAGGAATGGACAAGAGTTGAGCAGCCTTTCTGCTGATTATCACACATCATGA
  81 GCTGAGTGACTGCAGCTTGCCAAATCTTTGTGTTTCTGGGTCTGACCAATTAGCTTAGTTCTTCTCCTGCCTAATTTTGA
 161 ACTAGTAAAGCAAAGTGAGTCATCAGATTATGAGTTACTGTTTAAAAGAAAAATGCTGTTTATTCATGCTGAGGTGATTC
 241 AGTTCCCTCCTTCTTACAGAAGTATTTTAATTCACCCCACACTAGAAATGCAGCATCTTTGTGGACGTCTTTTTCACAAG
 321 CCTCCAAGGCTCCTTAGATTGGGTCGTTACTAAAAGTACATTAAAACACTCTTGTTTATCGAAGTATATTGATGTATTCT
 401 AAAGCTAGTAAACTTCCCTAACGTTTAATTGCCCTACAGATGCTTCTCTTGCTGTGGGTTTTCTTTTGTTAGTGGTCTGA
 481 AATAATTATTTTCCTGTTCTATTAATACATAGTGTATTTTGCACAAAAAAATTAACCTGGTCAATAGTGATTACCAAAAT
 561 ATATATTAATAATCTTGGCAATTTTTGACATTAATTATGAAACATTTTAGCCCACGTTAGTTCTACATTATTCTTCACTT
 641 AAACTCAGCTACTGCAAATTTTGTCTTTCTGTAAATGTTATTAAAATATCCAGTGAGCTCTTTAGAAGGACTCAGTATTA
 721 TTTCAAGACTATTTTTGAGGTAATTCTAGCCTTTTAAAATATTCTACAGACCTACGGGGCTTAAAAGAACCCCAGTACCG
 801 ACTAAGCAAATAGGCAAAAGACATGTTGGAAATGTAGTATAGTACTTGAAACAGTCACTATCATAGGGATAATTGGTGCA
 881 TCCTGTGTAAATGGAAGCTGAGCTTGACACCTGGTGCTTTTAAGTAGGGATAAAGTCATCCTCTCACTGCAAGCACAGCA
 961 TACCTGTACCTCCAAAAGTGACGTTTTAGTGAACAGGCCGTTTTCAACACTTGTGCCTTGGGGTGTTCATTGAAGCTTTG
1041 TGAAAACTACTGATGTTTTCTCAGTCTCCTTAAAGTTACGTCCATGCTTTAAAATGTCTGTGTAGGAGAGAAGTGGGGTT
1121 TATAATGTTTTCTCTAAGATATCTTTGCTGCTTTCCAGACTTTGAAACTATTAAGCTTCTTAACTGCCTCTTACCGGAAA
1201 TACTTCTGGGGAAACTTCATGGTCCCAAAATGTCATTGCCATACAGCTTCACTAGAGTTCTTTGAACCACAGCTGAAAAG
1281 AGCTTTGTATTATTTTTTAATTCCCTCCCCAGATATCATTTAGGAGTATTATATAAAGGTGGTGGGCAAAAACAATGTAA
1361 GGAGCCTTTCCAGTTATCTTGAGTTGCAGCTCTGTAGTTTCTTGAGGCCAAACACACTGTATTTTACAAGTCAAAATATA
1441 ATTTACATTAATCACTATGTTAATGAGTATGTAAAACATTCTTTTGCATTGATGAATTTTGTATCTGCTTCCATTAAAAG
1521 CATAACAGCCATAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaUUCUCAGAGGGGGACAUAUa 5'
            ||  | : | :|||||:|| 
Target 5' atAATTGGTGCATCCTGTGTAa 3'
 869 - 890 136.00 -11.40
2 
miRNA  3' uauuCUCAG---AGGGGGACAUAua 5'
              ||| |    | | ||||||  
Target 5' tcttGAGGCCAAACACACTGTATtt 3'
 1400 - 1424 126.00 -9.30
3 
miRNA  3' uauucucagagggGGACAUAUa 5'
                       :||||:|| 
Target 5' atgctttaaaatgTCTGTGTAg 3'
 1084 - 1105 125.00 -7.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs74877435 2215 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1370376645 1 dbSNP
rs782661260 4 dbSNP
rs1410861802 14 dbSNP
rs535978067 23 dbSNP
rs1376531618 24 dbSNP
rs1312889917 27 dbSNP
rs1322981274 29 dbSNP
rs559639761 44 dbSNP
rs1225208637 49 dbSNP
rs528403822 57 dbSNP
rs1483316158 61 dbSNP
rs781782806 63 dbSNP
rs1207057517 66 dbSNP
rs530365716 73 dbSNP
rs1255056653 83 dbSNP
rs1482439591 90 dbSNP
rs1181486172 96 dbSNP
rs1414689221 101 dbSNP
rs1425600120 112 dbSNP
rs1166753529 125 dbSNP
rs1390125289 129 dbSNP
rs1430892024 130 dbSNP
rs1170881771 138 dbSNP
rs1357779341 144 dbSNP
rs1446907050 154 dbSNP
rs1303042636 159 dbSNP
rs1380756299 167 dbSNP
rs144139077 167 dbSNP
rs182181823 168 dbSNP
rs1296158787 180 dbSNP
rs1342797852 190 dbSNP
rs1230519297 193 dbSNP
rs1277996912 207 dbSNP
rs1311370038 215 dbSNP
rs782452300 216 dbSNP
rs1209731273 218 dbSNP
rs1238301223 239 dbSNP
rs571663939 246 dbSNP
rs1484330935 260 dbSNP
rs1186768971 266 dbSNP
rs1247423312 274 dbSNP
rs1450710829 281 dbSNP
rs1171013942 286 dbSNP
rs530960308 288 dbSNP
rs1414229728 292 dbSNP
rs1177188825 306 dbSNP
rs141307793 330 dbSNP
rs1455259736 330 dbSNP
rs750902870 330 dbSNP
rs1319386402 335 dbSNP
rs1365279696 342 dbSNP
rs1437250903 356 dbSNP
rs1272970001 366 dbSNP
rs144752169 369 dbSNP
rs1280402409 371 dbSNP
rs1325930229 375 dbSNP
rs1207053734 379 dbSNP
rs147899729 384 dbSNP
rs1465383141 385 dbSNP
rs1191093341 387 dbSNP
rs1245512593 388 dbSNP
rs1477958466 402 dbSNP
rs146434039 404 dbSNP
rs1427696547 409 dbSNP
rs1471441716 411 dbSNP
rs553156013 420 dbSNP
rs1388784333 429 dbSNP
rs1458389617 431 dbSNP
rs1320961388 440 dbSNP
rs1349237707 450 dbSNP
rs566784833 462 dbSNP
rs77678863 465 dbSNP
rs1276466707 468 dbSNP
rs1348380770 470 dbSNP
rs1226843293 471 dbSNP
rs1287925463 477 dbSNP
rs1330038958 478 dbSNP
rs1206993490 484 dbSNP
rs1287738347 484 dbSNP
rs1451607519 493 dbSNP
rs1222938340 494 dbSNP
rs1271569048 495 dbSNP
rs1471797632 500 dbSNP
rs1181861834 504 dbSNP
rs1412288187 507 dbSNP
rs1473336347 521 dbSNP
rs1160954014 524 dbSNP
rs1412436854 533 dbSNP
rs1405941330 541 dbSNP
rs1325417861 547 dbSNP
rs1368512418 557 dbSNP
rs56148635 562 dbSNP
rs1308353247 573 dbSNP
rs782116796 573 dbSNP
rs1351349173 575 dbSNP
rs1241449908 578 dbSNP
rs148940757 584 dbSNP
rs1229438688 585 dbSNP
rs1294627446 587 dbSNP
rs1482333514 587 dbSNP
rs1204910927 590 dbSNP
rs1252905457 593 dbSNP
rs1439260585 595 dbSNP
rs782492608 598 dbSNP
rs1236437416 600 dbSNP
rs1472820677 605 dbSNP
rs117013736 606 dbSNP
rs1388270484 615 dbSNP
rs1428961945 625 dbSNP
rs1169060393 632 dbSNP
rs556749056 637 dbSNP
rs1372165082 645 dbSNP
rs1393413188 649 dbSNP
rs1332403393 653 dbSNP
rs573702440 655 dbSNP
rs1448877260 658 dbSNP
rs782235571 661 dbSNP
rs1317179201 664 dbSNP
rs1340668582 669 dbSNP
rs1228304383 673 dbSNP
rs1275868773 679 dbSNP
rs1341882362 681 dbSNP
rs1198412633 686 dbSNP
rs1255080061 689 dbSNP
rs558528086 693 dbSNP
rs1442584369 694 dbSNP
rs782314426 699 dbSNP
rs1184913782 714 dbSNP
rs1245591738 715 dbSNP
rs1448854371 717 dbSNP
rs1189116482 725 dbSNP
rs1374629340 729 dbSNP
rs1464387963 730 dbSNP
rs578246125 743 dbSNP
rs1171731046 746 dbSNP
rs1401786685 749 dbSNP
rs534225975 756 dbSNP
rs1435074144 757 dbSNP
rs1298949895 759 dbSNP
rs1328664214 764 dbSNP
rs1231556033 766 dbSNP
rs1255710202 777 dbSNP
rs185872966 781 dbSNP
rs1205163441 783 dbSNP
rs1265752928 789 dbSNP
rs1464027519 793 dbSNP
rs1208771449 802 dbSNP
rs1263794983 822 dbSNP
rs1431313403 827 dbSNP
rs1197913203 831 dbSNP
rs1377986432 838 dbSNP
rs113678668 862 dbSNP
rs528341678 863 dbSNP
rs1178822220 873 dbSNP
rs1386595339 878 dbSNP
rs1456808225 881 dbSNP
rs1321241952 898 dbSNP
rs1387789523 902 dbSNP
rs368158908 915 dbSNP
rs1385524695 925 dbSNP
rs1301093387 926 dbSNP
rs1225011468 929 dbSNP
rs1332021210 929 dbSNP
rs1286109654 945 dbSNP
rs1327996150 952 dbSNP
rs1228486031 960 dbSNP
rs1261903170 974 dbSNP
rs1487504309 981 dbSNP
rs1209150253 985 dbSNP
rs1267854558 997 dbSNP
rs1490770158 1003 dbSNP
rs1179697143 1011 dbSNP
rs1410056866 1012 dbSNP
rs1472352053 1015 dbSNP
rs1159926552 1022 dbSNP
rs1365598512 1041 dbSNP
rs1456887300 1046 dbSNP
rs1293429477 1048 dbSNP
rs1366696103 1051 dbSNP
rs1407175392 1052 dbSNP
rs1306498717 1061 dbSNP
rs549941502 1066 dbSNP
rs1228618695 1076 dbSNP
rs1308592241 1081 dbSNP
rs1319379023 1088 dbSNP
rs1244024432 1090 dbSNP
rs1265992383 1092 dbSNP
rs188383334 1098 dbSNP
rs1361445001 1100 dbSNP
rs1202774429 1111 dbSNP
rs1250708866 1122 dbSNP
rs1482888588 1126 dbSNP
rs1177981762 1129 dbSNP
rs1252804650 1136 dbSNP
rs181251564 1143 dbSNP
rs567604332 1149 dbSNP
rs781938889 1150 dbSNP
rs1386429709 1158 dbSNP
rs1427032413 1162 dbSNP
rs1167179476 1164 dbSNP
rs1370325555 1166 dbSNP
rs1442553115 1167 dbSNP
rs1299493477 1168 dbSNP
rs1376466357 1170 dbSNP
rs1394969301 1176 dbSNP
rs1315064064 1182 dbSNP
rs1384907727 1184 dbSNP
rs7475112 1186 dbSNP
rs1226075166 1187 dbSNP
rs184975299 1191 dbSNP
rs1342572691 1193 dbSNP
rs546731603 1196 dbSNP
rs1253325144 1202 dbSNP
rs1482368957 1203 dbSNP
rs1243820703 1206 dbSNP
rs1447040270 1212 dbSNP
rs1187203833 1218 dbSNP
rs191140574 1220 dbSNP
rs538876766 1222 dbSNP
rs552437585 1225 dbSNP
rs1410908362 1228 dbSNP
rs1172925500 1234 dbSNP
rs7475117 1235 dbSNP
rs1336890807 1236 dbSNP
rs1384344053 1246 dbSNP
rs753967214 1261 dbSNP
rs1362516926 1262 dbSNP
rs1216127561 1274 dbSNP
rs4628626 1278 dbSNP
rs183807934 1279 dbSNP
rs1310736265 1281 dbSNP
rs1209667382 1290 dbSNP
rs1263889250 1292 dbSNP
rs4322342 1294 dbSNP
rs1462688070 1298 dbSNP
rs1206853944 1308 dbSNP
rs1247971865 1310 dbSNP
rs536616685 1319 dbSNP
rs1188662675 1324 dbSNP
rs1423499693 1325 dbSNP
rs556924254 1331 dbSNP
rs1176678071 1332 dbSNP
rs553901021 1337 dbSNP
rs1455210116 1339 dbSNP
rs148075416 1341 dbSNP
rs573944101 1347 dbSNP
rs1432809098 1348 dbSNP
rs113017697 1352 dbSNP
rs1366619461 1367 dbSNP
rs1223177464 1369 dbSNP
rs1284199151 1369 dbSNP
rs1325863905 1370 dbSNP
rs1226660073 1376 dbSNP
rs562597245 1376 dbSNP
rs371513412 1377 dbSNP
rs545236938 1378 dbSNP
rs1448144451 1387 dbSNP
rs1218542578 1395 dbSNP
rs779225069 1401 dbSNP
rs1488340235 1409 dbSNP
rs1200538346 1411 dbSNP
rs1430994897 1416 dbSNP
rs1471368028 1422 dbSNP
rs1157861324 1426 dbSNP
rs1408061132 1428 dbSNP
rs1402430336 1433 dbSNP
rs1321477275 1443 dbSNP
rs565003127 1447 dbSNP
rs7478470 1453 dbSNP
rs1405350584 1460 dbSNP
rs1304666801 1472 dbSNP
rs1347622994 1474 dbSNP
rs1408228141 1479 dbSNP
rs1279097165 1495 dbSNP
rs1351464568 1500 dbSNP
rs1226016744 1501 dbSNP
rs10995571 1502 dbSNP
rs1359278309 1503 dbSNP
rs544241935 1508 dbSNP
rs1271489017 1519 dbSNP
rs1180982756 1522 dbSNP
rs1470897426 1528 dbSNP
rs1160896429 1535 dbSNP
rs1412991522 1536 dbSNP
rs1425144595 1537 dbSNP
rs1165306092 1538 dbSNP
rs1368457333 1539 dbSNP
rs1428116354 1539 dbSNP
rs1328397272 1540 dbSNP
rs1336535787 1542 dbSNP
rs1444480617 1544 dbSNP
rs1282435767 1545 dbSNP
rs1247334761 1546 dbSNP
rs1382789334 1546 dbSNP
rs1294473060 1550 dbSNP
rs1340444674 1561 dbSNP
rs1273302300 1563 dbSNP
rs74646800 1564 dbSNP
rs1439131645 1565 dbSNP
rs1168226182 1566 dbSNP
rs1184780940 1566 dbSNP
rs1185323440 1566 dbSNP
rs1204973082 1566 dbSNP
rs1227166100 1566 dbSNP
rs1241978855 1566 dbSNP
rs1271065487 1566 dbSNP
rs1317817893 1566 dbSNP
rs1332341818 1566 dbSNP
rs1363584570 1566 dbSNP
rs1388131838 1566 dbSNP
rs1397491087 1566 dbSNP
rs1405417927 1566 dbSNP
rs1411863500 1566 dbSNP
rs1428903539 1566 dbSNP
rs1445225634 1566 dbSNP
rs1454023871 1566 dbSNP
rs71026287 1566 dbSNP
rs77725859 1566 dbSNP
rs1246137430 1567 dbSNP
rs187653971 1567 dbSNP
rs1174513098 1568 dbSNP
rs1374570622 1568 dbSNP
rs1476541593 1568 dbSNP
rs561327062 1568 dbSNP
rs1470358645 1569 dbSNP
rs1338719204 1570 dbSNP
rs1387092995 1575 dbSNP
rs530085400 1576 dbSNP
rs1382150297 1580 dbSNP
rs1319455961 1582 dbSNP
rs1328537890 1587 dbSNP
rs1230658682 1589 dbSNP
rs1282276550 1592 dbSNP
rs191578158 1599 dbSNP
rs1265695291 1600 dbSNP
rs781951071 1600 dbSNP
rs1485536527 1606 dbSNP
rs1205626591 1607 dbSNP
rs1263638146 1612 dbSNP
rs1449690775 1616 dbSNP
rs1198364262 1619 dbSNP
rs138976963 1629 dbSNP
rs1428879360 1632 dbSNP
rs1480846324 1633 dbSNP
rs1178755161 1640 dbSNP
rs532533667 1643 dbSNP
rs1453731635 1648 dbSNP
rs1159621507 1656 dbSNP
rs782046445 1658 dbSNP
rs371475847 1659 dbSNP
rs758244905 1661 dbSNP
rs1302862270 1663 dbSNP
rs1345825928 1669 dbSNP
rs142126211 1671 dbSNP
rs1285968550 1672 dbSNP
rs1315780291 1676 dbSNP
rs1239094425 1678 dbSNP
rs1262448491 1684 dbSNP
rs1354099251 1684 dbSNP
rs1221475501 1695 dbSNP
rs569403828 1697 dbSNP
rs1490590792 1702 dbSNP
rs1201825792 1707 dbSNP
rs1248555124 1708 dbSNP
rs1418610535 1711 dbSNP
rs538520230 1714 dbSNP
rs564872273 1725 dbSNP
rs548647266 1726 dbSNP
rs1163411273 1729 dbSNP
rs1366560336 1741 dbSNP
rs1426207362 1747 dbSNP
rs1296128958 1754 dbSNP
rs1372102867 1759 dbSNP
rs1391479539 1761 dbSNP
rs1308437444 1773 dbSNP
rs567231421 1778 dbSNP
rs1338695474 1793 dbSNP
rs1245132645 1799 dbSNP
rs1361287014 1800 dbSNP
rs1202711252 1805 dbSNP
rs1249856326 1811 dbSNP
rs782710275 1811 dbSNP
rs1196459569 1813 dbSNP
rs1252741875 1816 dbSNP
rs1443382059 1818 dbSNP
rs777751577 1820 dbSNP
rs1183485217 1822 dbSNP
rs1386361543 1825 dbSNP
rs1446849856 1828 dbSNP
rs781891000 1832 dbSNP
rs1353567695 1844 dbSNP
rs1462178362 1848 dbSNP
rs1299438417 1852 dbSNP
rs1403235102 1854 dbSNP
rs1451871548 1855 dbSNP
rs1315677696 1856 dbSNP
rs1384842443 1858 dbSNP
rs1212601444 1859 dbSNP
rs781817350 1859 dbSNP
rs1294500629 1862 dbSNP
rs1307194002 1875 dbSNP
rs1205463400 1882 dbSNP
rs145386979 1887 dbSNP
rs1460061323 1891 dbSNP
rs1203064556 1893 dbSNP
rs782551250 1904 dbSNP
rs1185216452 1905 dbSNP
rs113512799 1917 dbSNP
rs1428795944 1918 dbSNP
rs1172040695 1926 dbSNP
rs1426717697 1942 dbSNP
rs1468852885 1943 dbSNP
rs1336750559 1945 dbSNP
rs1428545793 1952 dbSNP
rs1288122578 1956 dbSNP
rs73314067 1962 dbSNP
rs1280360916 1965 dbSNP
rs1321605360 1967 dbSNP
rs572994261 1969 dbSNP
rs1263830439 1973 dbSNP
rs1326356726 1976 dbSNP
rs373515919 1983 dbSNP
rs1214241869 1985 dbSNP
rs782500850 1986 dbSNP
rs538789678 1989 dbSNP
rs1266344621 1990 dbSNP
rs1479866693 1991 dbSNP
rs558724672 1996 dbSNP
rs1176611139 2000 dbSNP
rs1430762719 2001 dbSNP
rs1398921842 2005 dbSNP
rs1158333835 2019 dbSNP
rs1345666742 2020 dbSNP
rs1432658935 2021 dbSNP
rs1300992954 2026 dbSNP
rs1343947892 2033 dbSNP
rs1404557558 2039 dbSNP
rs1284052716 2048 dbSNP
rs1347171213 2058 dbSNP
rs782563640 2059 dbSNP
rs1284205103 2062 dbSNP
rs1317985436 2066 dbSNP
rs1219251596 2071 dbSNP
rs1290037203 2077 dbSNP
rs1490100908 2080 dbSNP
rs782348287 2083 dbSNP
rs1199658996 2084 dbSNP
rs1270543599 2085 dbSNP
rs1468177339 2087 dbSNP
rs1176069994 2091 dbSNP
rs1408639850 2091 dbSNP
rs1402372641 2097 dbSNP
rs1161508939 2111 dbSNP
rs1364712838 2117 dbSNP
rs1424304624 2130 dbSNP
rs1304009594 2139 dbSNP
rs575391262 2146 dbSNP
rs782199739 2147 dbSNP
rs1242935263 2150 dbSNP
rs544493152 2156 dbSNP
rs561058734 2157 dbSNP
rs782545284 2159 dbSNP
rs569850734 2161 dbSNP
rs1291598840 2162 dbSNP
rs1203291556 2164 dbSNP
rs770955587 2167 dbSNP
rs782253588 2169 dbSNP
rs782390511 2170 dbSNP
rs1445039377 2172 dbSNP
rs1165171807 2174 dbSNP
rs1393150194 2175 dbSNP
rs1408421545 2182 dbSNP
rs149471887 2187 dbSNP
rs560186777 2193 dbSNP
rs143877889 2196 dbSNP
rs1313583565 2200 dbSNP
rs1382618242 2209 dbSNP
rs552430686 2210 dbSNP
rs1247182606 2212 dbSNP
rs74877435 2215 dbSNP
rs1337108910 2216 dbSNP
rs1213609435 2218 dbSNP
rs1273151600 2228 dbSNP
rs75301470 2229 dbSNP
rs77151340 2232 dbSNP
rs77335549 2233 dbSNP
rs1458734761 2247 dbSNP
rs370494304 2247 dbSNP
rs1201175662 2254 dbSNP
rs1242469187 2259 dbSNP
rs1461659149 2261 dbSNP
rs1189439045 2271 dbSNP
rs1474577924 2274 dbSNP
rs1167524456 2282 dbSNP
rs1420434374 2283 dbSNP
rs1467261597 2295 dbSNP
rs1334706276 2299 dbSNP
rs1406085467 2300 dbSNP
rs370516856 2300 dbSNP
rs1336617059 2310 dbSNP
rs1325020619 2315 dbSNP
rs1430404235 2317 dbSNP
rs782149987 2321 dbSNP
rs1319485571 2322 dbSNP
rs1221156518 2326 dbSNP
rs1261960431 2329 dbSNP
rs1324264821 2336 dbSNP
rs1202085989 2355 dbSNP
rs1259447042 2357 dbSNP
rs148603576 2364 dbSNP
rs142919038 2365 dbSNP
rs1264176804 2367 dbSNP
rs1478923644 2370 dbSNP
rs1174444643 2372 dbSNP
rs1428660777 2374 dbSNP
rs1467041476 2379 dbSNP
rs1174864765 2380 dbSNP
rs532437304 2382 dbSNP
rs1382020004 2383 dbSNP
rs147426016 2384 dbSNP
rs1342057442 2385 dbSNP
rs1402703009 2389 dbSNP
rs1282141393 2395 dbSNP
rs139701971 2418 dbSNP
rs1234730806 2420 dbSNP
rs1258905807 2422 dbSNP
rs1349785575 2427 dbSNP
rs80329954 2439 dbSNP
rs1287880166 2449 dbSNP
rs1489423930 2457 dbSNP
rs1197504236 2458 dbSNP
rs1268403818 2462 dbSNP
rs1433861537 2467 dbSNP
rs367654461 2471 dbSNP
rs12571253 2474 dbSNP
rs1453664976 2475 dbSNP
rs1159687475 2487 dbSNP
rs558416554 2488 dbSNP
rs569015169 2499 dbSNP
rs782599669 2502 dbSNP
rs1422404977 2506 dbSNP
rs200167458 2513 dbSNP
rs782309843 2514 dbSNP
rs782035256 2517 dbSNP
rs782741655 2523 dbSNP
rs1304226840 2524 dbSNP
rs1335161481 2525 dbSNP
rs782746044 2525 dbSNP
rs1239655785 2526 dbSNP
rs1311239786 2528 dbSNP
rs1357053644 2533 dbSNP
rs1221401277 2534 dbSNP
rs374998324 2536 dbSNP
rs781853489 2540 dbSNP
rs782379123 2550 dbSNP
rs781980915 2552 dbSNP
rs782091072 2558 dbSNP
rs782174928 2564 dbSNP
rs782518806 2566 dbSNP
rs368134933 2567 dbSNP
rs370635886 2570 dbSNP
rs182868699 2571 dbSNP
rs782741575 2572 dbSNP
rs1179777958 2574 dbSNP
rs1382658566 2579 dbSNP
rs1443189812 2583 dbSNP
rs373790279 2586 dbSNP
rs1459111301 2587 dbSNP
rs782566865 2592 dbSNP
rs1395108694 2595 dbSNP
rs560729804 2599 dbSNP
rs1333314008 2601 dbSNP
rs1446833872 2601 dbSNP
rs782295183 2602 dbSNP
rs201479189 2604 dbSNP
rs1244975990 2605 dbSNP
rs1315462166 2611 dbSNP
rs372429941 2616 dbSNP
rs1247229468 2619 dbSNP
rs1249729963 2629 dbSNP
rs1480366419 2636 dbSNP
rs1199296707 2640 dbSNP
rs1240577998 2642 dbSNP
rs1460368623 2646 dbSNP
rs540189769 2659 dbSNP
rs553761205 2664 dbSNP
rs1425232521 2665 dbSNP
rs1167922829 2672 dbSNP
rs1372098041 2675 dbSNP
rs781891600 2679 dbSNP
rs1465705868 2693 dbSNP
rs1172104898 2698 dbSNP
rs1403899020 2701 dbSNP
rs1451806136 2707 dbSNP
rs1303260030 2710 dbSNP
rs1381028528 2714 dbSNP
rs576872026 2719 dbSNP
rs1293730514 2720 dbSNP
rs1219400588 2726 dbSNP
rs1307078180 2726 dbSNP
rs1260062444 2728 dbSNP
rs1322098281 2730 dbSNP
rs1203557715 2740 dbSNP
rs1238520519 2741 dbSNP
rs1484458054 2743 dbSNP
rs374871612 2757 dbSNP
rs1260612527 2761 dbSNP
rs1477938984 2764 dbSNP
rs1195282776 2768 dbSNP
rs7079822 2772 dbSNP
rs1469263079 2775 dbSNP
rs113983044 2778 dbSNP
rs1288069150 2779 dbSNP
rs147602077 2781 dbSNP
rs1400809911 2782 dbSNP
rs1280217374 2784 dbSNP
rs1343752293 2800 dbSNP
rs868928260 2806 dbSNP
rs1279965062 2807 dbSNP
rs187549764 2808 dbSNP
rs1214184341 2811 dbSNP
rs1260495828 2813 dbSNP
rs1488442776 2814 dbSNP
rs1195359931 2826 dbSNP
rs1266280505 2827 dbSNP
rs781911213 2839 dbSNP
rs1191212524 2861 dbSNP
rs7079949 2871 dbSNP
rs544076481 2872 dbSNP
rs1158167204 2875 dbSNP
rs1360893098 2882 dbSNP
rs1421244944 2886 dbSNP
rs1300304136 2889 dbSNP
rs1363878352 2896 dbSNP
rs1435846892 2899 dbSNP
rs11548236 2906 dbSNP
rs1309043019 2907 dbSNP
rs1354910770 2910 dbSNP
rs1219186431 2914 dbSNP
rs1289159665 2918 dbSNP
rs1450617993 2919 dbSNP
rs1221736229 2920 dbSNP
rs1247924994 2924 dbSNP
rs1176581908 2925 dbSNP
rs1380785777 2926 dbSNP
rs1441325035 2930 dbSNP
rs1161361081 2931 dbSNP
rs117430945 2934 dbSNP
rs1324342535 2939 dbSNP
rs571841348 2940 dbSNP
rs1440065823 2948 dbSNP
rs1331286286 2958 dbSNP
rs1378228310 2965 dbSNP
rs1242774515 2969 dbSNP
rs552237578 2972 dbSNP
rs781828816 2976 dbSNP
rs191675592 2978 dbSNP
rs1291528003 2988 dbSNP
rs1435589803 2989 dbSNP
rs1197393011 2992 dbSNP
rs1181592949 2994 dbSNP
rs1238714973 2994 dbSNP
rs1459028176 2994 dbSNP
rs1472616852 3001 dbSNP
rs1164084195 3004 dbSNP
rs1416169859 3008 dbSNP
rs118187389 3013 dbSNP
rs1169977247 3028 dbSNP
rs1401746735 3030 dbSNP
rs1449624051 3032 dbSNP
rs559757030 3036 dbSNP
rs1340279956 3038 dbSNP
rs1449145378 3039 dbSNP
rs182769707 3042 dbSNP
rs1336966329 3052 dbSNP
rs1217550974 3055 dbSNP
rs1258123130 3059 dbSNP
rs1319984160 3063 dbSNP
rs1201659241 3070 dbSNP
rs187538862 3071 dbSNP
rs1239438637 3073 dbSNP
rs782185716 3074 dbSNP
rs1424383887 3079 dbSNP
rs1467212460 3087 dbSNP
rs1174935228 3089 dbSNP
rs1402046687 3090 dbSNP
rs1415406393 3093 dbSNP
rs1336551030 3096 dbSNP
rs1324380583 3097 dbSNP
rs1398989899 3100 dbSNP
rs782649291 3100 dbSNP
rs782394894 3101 dbSNP
rs1341871004 3104 dbSNP
rs1221104364 3123 dbSNP
rs1255355460 3124 dbSNP
rs782681587 3138 dbSNP
rs1345548660 3141 dbSNP
rs1202035285 3142 dbSNP
rs139310123 3142 dbSNP
rs192790867 3143 dbSNP
rs1487453366 3149 dbSNP
rs1216203422 3153 dbSNP
rs185540699 3153 dbSNP
rs773624546 3153 dbSNP
rs1478850606 3156 dbSNP
rs1196760919 3167 dbSNP
rs1377620686 3169 dbSNP
rs1478633275 3177 dbSNP
rs1174724109 3178 dbSNP
rs1383225749 3189 dbSNP
rs1419444089 3193 dbSNP
rs1298459478 3195 dbSNP
rs1362003974 3197 dbSNP
rs1402561861 3216 dbSNP
rs1299987584 3221 dbSNP
rs1331667722 3235 dbSNP
rs1235298141 3237 dbSNP
rs1277658592 3245 dbSNP
rs1352744767 3246 dbSNP
rs1240528779 3247 dbSNP
rs1287013414 3257 dbSNP
rs545892791 3261 dbSNP
rs534239976 3278 dbSNP
rs1266727206 3285 dbSNP
rs556590656 3289 dbSNP
rs576460172 3293 dbSNP
rs1201691372 3298 dbSNP
rs1378955315 3299 dbSNP
rs1439488629 3300 dbSNP
rs1159559817 3301 dbSNP
rs1381856341 3302 dbSNP
rs34420309 3302 dbSNP
rs14818 3306 dbSNP
rs35603872 3316 dbSNP
rs1292486241 3317 dbSNP
rs149999841 3325 dbSNP
rs1387956613 3326 dbSNP
rs1326784369 3328 dbSNP
rs1375970865 3331 dbSNP
rs1240684192 3335 dbSNP
rs111347745 3343 dbSNP
rs1356176598 3344 dbSNP
rs1242836918 3346 dbSNP
rs560900792 3346 dbSNP
rs1265047508 3351 dbSNP
rs1357174724 3352 dbSNP
rs1211656799 3366 dbSNP
rs1236893808 3368 dbSNP
rs1179721889 3369 dbSNP
rs1457709177 3369 dbSNP
rs1240390178 3374 dbSNP
rs1421730464 3375 dbSNP
rs1163662141 3380 dbSNP
rs562256246 3384 dbSNP
rs1368625558 3386 dbSNP
rs1458997239 3388 dbSNP
rs1167910433 3399 dbSNP
rs1399529273 3404 dbSNP
rs1333162810 3405 dbSNP
rs781946908 3408 dbSNP
rs1376737753 3411 dbSNP
rs1395193238 3412 dbSNP
rs1312299719 3413 dbSNP
rs1341227298 3414 dbSNP
rs527937577 3419 dbSNP
rs782328751 3420 dbSNP
rs1256223661 3421 dbSNP
rs1317887409 3440 dbSNP
rs190445657 3450 dbSNP
rs879979243 3451 dbSNP
rs1482488674 3453 dbSNP
rs1181569638 3454 dbSNP
rs1256500946 3460 dbSNP
rs1425170461 3463 dbSNP
rs1190934472 3469 dbSNP
rs192532512 3487 dbSNP
rs1465650616 3493 dbSNP
rs564807619 3495 dbSNP
rs184223236 3504 dbSNP
rs1357304277 3508 dbSNP
rs1465365318 3509 dbSNP
rs1303209612 3513 dbSNP
rs1403253874 3517 dbSNP
rs1416833682 3519 dbSNP
rs1339983509 3525 dbSNP
rs551907679 3533 dbSNP
rs1280655693 3536 dbSNP
rs1310950485 3564 dbSNP
rs1209927003 3576 dbSNP
rs1256930323 3579 dbSNP
rs1484051554 3580 dbSNP
rs782167447 3590 dbSNP
rs1261951354 3600 dbSNP
rs1477871884 3602 dbSNP
rs782770589 3605 dbSNP
rs567556405 3606 dbSNP
rs1423063776 3610 dbSNP
rs145206481 3634 dbSNP
rs1176585806 3636 dbSNP
rs782090593 3647 dbSNP
rs1360654238 3648 dbSNP
rs1417589546 3650 dbSNP
rs1296596294 3653 dbSNP
rs1360060694 3657 dbSNP
rs1290694891 3658 dbSNP
rs189027941 3665 dbSNP
rs1219121285 3678 dbSNP
rs1302533368 3696 dbSNP
rs552177668 3697 dbSNP
rs782272933 3699 dbSNP
rs1238359646 3701 dbSNP
rs1284875487 3704 dbSNP
rs782053524 3705 dbSNP
rs1218241057 3706 dbSNP
rs782618832 3706 dbSNP
rs782739452 3707 dbSNP
rs1244453382 3708 dbSNP
rs1488139831 3719 dbSNP
rs369412918 3719 dbSNP
rs78473923 3721 dbSNP
rs1427120054 3722 dbSNP
rs782669078 3729 dbSNP
rs374896405 3732 dbSNP
rs181114315 3736 dbSNP
rs1379980699 3740 dbSNP
rs782519730 3757 dbSNP
rs374163938 3760 dbSNP
rs570677050 3762 dbSNP
rs1348234785 3764 dbSNP
rs1435786506 3766 dbSNP
rs766915189 3770 dbSNP
rs1294641264 3780 dbSNP
rs1373749390 3781 dbSNP
rs782513132 3794 dbSNP
rs1445119194 3797 dbSNP
rs539771687 3813 dbSNP
rs1308976205 3814 dbSNP
rs1354034327 3816 dbSNP
rs1225083465 3822 dbSNP
rs1287257198 3825 dbSNP
rs1320618700 3831 dbSNP
rs1221573818 3838 dbSNP
rs556290659 3839 dbSNP
rs149132530 3841 dbSNP
rs1441269170 3842 dbSNP
rs782648690 3842 dbSNP
rs1160535292 3843 dbSNP
rs115895891 3844 dbSNP
rs1404848169 3849 dbSNP
rs1165570106 3851 dbSNP
rs1397399591 3856 dbSNP
rs1464503813 3862 dbSNP
rs1331146934 3871 dbSNP
rs753819895 3873 dbSNP
rs1378151221 3874 dbSNP
rs1444756049 3879 dbSNP
rs1282083761 3882 dbSNP
rs566019531 3883 dbSNP
rs1377981852 3892 dbSNP
rs1228450782 3893 dbSNP
rs1274483413 3899 dbSNP
rs572663301 3903 dbSNP
rs1197966113 3909 dbSNP
rs1258573749 3913 dbSNP
rs1439355132 3920 dbSNP
rs759681928 3927 dbSNP
rs1185054899 3928 dbSNP
rs1236016137 3929 dbSNP
rs1472586221 3930 dbSNP
rs1182573417 3945 dbSNP
rs1420079445 3947 dbSNP
rs1476859410 3958 dbSNP
rs1170625365 3965 dbSNP
rs1401590162 3966 dbSNP
rs782212272 3969 dbSNP
rs1332591539 3985 dbSNP
rs782313424 3989 dbSNP
rs1448259441 3998 dbSNP
rs1294698920 3999 dbSNP
rs1337801338 4006 dbSNP
rs1217422593 4007 dbSNP
rs541662906 4012 dbSNP
rs1278764990 4027 dbSNP
rs564744480 4048 dbSNP
rs1277633957 4050 dbSNP
rs200160746 4051 dbSNP
rs139489468 4052 dbSNP
rs1442104170 4057 dbSNP
rs1211904951 4058 dbSNP
rs186708439 4060 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions islets
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO. ...

- Kameswaran V; Bramswig NC; McKenna LB; Penn et al., 2014, Cell metabolism.

Article - Kameswaran V; Bramswig NC; McKenna LB; Penn et al.
- Cell metabolism, 2014
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing beta cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the pathogenesis of human T2DM, we sequenced the small RNAs of human islets from diabetic and nondiabetic organ donors. We identified a cluster of microRNAs in an imprinted locus on human chromosome 14q32 that is highly and specifically expressed in human beta cells and dramatically downregulated in islets from T2DM organ donors. The downregulation of this locus strongly correlates with hypermethylation of its promoter. Using HITS-CLIP for the essential RISC-component Argonaute, we identified disease-relevant targets of the chromosome 14q32 microRNAs, such as IAPP and TP53INP1, that cause increased beta cell apoptosis upon overexpression in human islets. Our results support a role for microRNAs and their epigenetic control by DNA methylation in the pathogenesis of T2DM.
LinkOut: [PMID: 24374217]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
114 hsa-miR-1185-1-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT066415 TBK1 TANK binding kinase 1 2 4
MIRT073567 NR2F2 nuclear receptor subfamily 2 group F member 2 2 2
MIRT074516 USP1 ubiquitin specific peptidase 1 2 4
MIRT080576 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 6
MIRT086539 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT086547 MOB4 MOB family member 4, phocein 2 2
MIRT088684 EML4 echinoderm microtubule associated protein like 4 2 4
MIRT090811 MBNL1 muscleblind like splicing regulator 1 2 4
MIRT095500 PURA purine rich element binding protein A 2 2
MIRT109530 KLHL15 kelch like family member 15 2 6
MIRT109807 ZFX zinc finger protein, X-linked 2 2
MIRT117888 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT120273 GSK3B glycogen synthase kinase 3 beta 2 4
MIRT149892 LDLR low density lipoprotein receptor 2 2
MIRT178475 LCOR ligand dependent nuclear receptor corepressor 2 4
MIRT193445 RORA RAR related orphan receptor A 2 2
MIRT198527 DSG2 desmoglein 2 2 2
MIRT226427 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT227669 SET SET nuclear proto-oncogene 2 2
MIRT320405 HOXA9 homeobox A9 2 2
MIRT407774 MRPL35 mitochondrial ribosomal protein L35 2 2
MIRT439228 ZMIZ1 zinc finger MIZ-type containing 1 1 1
MIRT439312 VAT1L vesicle amine transport 1 like 1 1
MIRT439421 TMOD1 tropomodulin 1 1 1
MIRT439446 TMEM104 transmembrane protein 104 1 1
MIRT439524 STIM2 stromal interaction molecule 2 1 1
MIRT439612 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 1 1
MIRT439997 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT440017 PCSK1 proprotein convertase subtilisin/kexin type 1 1 1
MIRT440131 NCOA4 nuclear receptor coactivator 4 1 1
MIRT440311 LRRC1 leucine rich repeat containing 1 1 1
MIRT440475 IAPP islet amyloid polypeptide 1 1
MIRT440511 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1 1
MIRT440617 FOXA2 forkhead box A2 1 1
MIRT440666 FBXL16 F-box and leucine rich repeat protein 16 1 1
MIRT440705 ERO1LB endoplasmic reticulum oxidoreductase 1 beta 1 1
MIRT441007 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 1 1
MIRT441018 CAND1 cullin associated and neddylation dissociated 1 1 1
MIRT441062 C1orf43 chromosome 1 open reading frame 43 1 1
MIRT441209 ARCN1 archain 1 1 1
MIRT449461 HAT1 histone acetyltransferase 1 2 2
MIRT467104 SRI sorcin 2 2
MIRT468060 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 10
MIRT468476 SESN3 sestrin 3 2 4
MIRT473533 MAX MYC associated factor X 2 2
MIRT473852 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT474711 KIF13A kinesin family member 13A 2 6
MIRT481665 ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2 2
MIRT485120 SF3B3 splicing factor 3b subunit 3 2 2
MIRT493055 MTFR1 mitochondrial fission regulator 1 2 2
MIRT504258 C1orf147 chromosome 1 open reading frame 147 2 4
MIRT504361 ARID1B AT-rich interaction domain 1B 2 4
MIRT505748 SENP1 SUMO1/sentrin specific peptidase 1 2 8
MIRT506298 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT508442 ZNF608 zinc finger protein 608 2 4
MIRT512782 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT520447 TSPAN2 tetraspanin 2 2 4
MIRT522133 NRBF2 nuclear receptor binding factor 2 2 6
MIRT522395 MYADM myeloid associated differentiation marker 2 4
MIRT523397 GRIK3 glutamate ionotropic receptor kainate type subunit 3 2 4
MIRT523938 E2F8 E2F transcription factor 8 2 4
MIRT524349 CREB1 cAMP responsive element binding protein 1 2 2
MIRT524711 BRMS1L breast cancer metastasis-suppressor 1 like 2 4
MIRT525134 ZNF256 zinc finger protein 256 2 2
MIRT525710 DCAF12L2 DDB1 and CUL4 associated factor 12 like 2 2 2
MIRT531264 PPIL3 peptidylprolyl isomerase like 3 2 2
MIRT538844 BTG1 BTG anti-proliferation factor 1 2 2
MIRT541366 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT542093 KCNK10 potassium two pore domain channel subfamily K member 10 2 6
MIRT543770 RBM12B RNA binding motif protein 12B 2 4
MIRT543940 NCOA7 nuclear receptor coactivator 7 2 2
MIRT545150 GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 2 2
MIRT545842 ZNF264 zinc finger protein 264 2 4
MIRT548057 GOLGA7 golgin A7 2 2
MIRT549242 ATXN1L ataxin 1 like 2 4
MIRT551829 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT552484 ZNF136 zinc finger protein 136 2 2
MIRT553663 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT554988 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT555760 PCTP phosphatidylcholine transfer protein 2 2
MIRT556923 IRF2BP2 interferon regulatory factor 2 binding protein 2 2 4
MIRT564991 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT566458 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT566538 PANK3 pantothenate kinase 3 2 2
MIRT567732 DLX2 distal-less homeobox 2 2 2
MIRT570081 KANSL1L KAT8 regulatory NSL complex subunit 1 like 2 2
MIRT571735 RNF11 ring finger protein 11 2 2
MIRT573529 MDM2 MDM2 proto-oncogene 2 2
MIRT574459 RPS16 ribosomal protein S16 2 2
MIRT574992 Phka1 phosphorylase kinase alpha 1 2 3
MIRT576349 Pxdn peroxidasin 2 2
MIRT610196 CD99 CD99 molecule (Xg blood group) 2 4
MIRT612920 GPRIN3 GPRIN family member 3 2 2
MIRT615021 DUSP6 dual specificity phosphatase 6 2 2
MIRT623573 IRS1 insulin receptor substrate 1 2 2
MIRT624437 CASD1 CAS1 domain containing 1 2 2
MIRT628714 ZNF585A zinc finger protein 585A 2 2
MIRT639565 PCK1 phosphoenolpyruvate carboxykinase 1 2 4
MIRT641485 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT641657 PAPOLG poly(A) polymerase gamma 2 2
MIRT642210 RUVBL2 RuvB like AAA ATPase 2 2 2
MIRT653010 STX7 syntaxin 7 2 2
MIRT656130 MSH6 mutS homolog 6 2 2
MIRT656893 KIAA2018 upstream transcription factor family member 3 2 2
MIRT660130 BRPF3 bromodomain and PHD finger containing 3 2 2
MIRT660855 AFAP1 actin filament associated protein 1 2 2
MIRT676843 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 3
MIRT681473 DIP2A disco interacting protein 2 homolog A 2 2
MIRT682253 RS1 retinoschisin 1 2 2
MIRT694296 COPB2 coatomer protein complex subunit beta 2 2 2
MIRT694401 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT705277 BACH1 BTB domain and CNC homolog 1 2 2
MIRT720833 C1orf52 chromosome 1 open reading frame 52 2 2
MIRT735713 SIRT1 sirtuin 1 2 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1185-1 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-1185-1 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1185-1-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-1185-1-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-1185-1-3p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-1185-1-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1185-1-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1185-1-3p Palbociclib 5330286 NSC758247 approved resistant cell line (T47D)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1185-1-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1185-1-3p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-miR-1185-1-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-1185-1-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-1185-1-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-1185-1-3p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-1185-1-3p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-1185-1-3p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-1185-1-3p Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-1185-1-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-1185-1-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

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