miRTarBase - #MIRT440135


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pre-miRNA Information
pre-miRNA hsa-mir-544a   
Genomic Coordinates chr14: 101048658 - 101048748
Description Homo sapiens miR-544a stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-544a
Sequence 55| AUUCUGCAUUUUUAGCAAGUUC |76
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1286637864 5 dbSNP
rs1394789797 9 dbSNP
rs1172200176 17 dbSNP
Putative Targets

Gene Information
Gene Symbol NCOA2   
Synonyms GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Description nuclear receptor coactivator 2
Transcript NM_006540   
Expression
Putative miRNA Targets on NCOA2
3'UTR of NCOA2
(miRNA target sites are highlighted)		 
>NCOA2|NM_006540|3'UTR
   1 CACTGCTGAAGCCAGTTGCTTCTTCAGCTGACCGGGCTCACTTGCTCAAAACACTTCCAGTCTGGAGAGCTGTGTCTATT
  81 TGTTTCAACCCAACTGACCTGCCAGCCGGTTCTGCTAGAGCAGACAGGCCTGGCCCTGGTTCCCAGGGTGGCGTCCACTC
 161 GGCTGTGGCAGGAGGAGCTGCCTCTTCTCTTGACAGTCTGAAGCTCGCATCCAGACAGTCGCTCAGTCTGTTCACTGCAT
 241 TCACCTTAGTGCAACTTAGATCTCTCCTGCAAAAGTAAATGTTGACAGGCAAATTTCATACCCATGTCAGATTGAATGTA
 321 TTTAAATGTATGTATTTAAGGAGAACCATGCTCTTGTTCTGTTCCTGTTCGGTTCCAGACACTGGTTTCTTGCTTTGTTT
 401 TCCCTGGCTAACAGTCTAGTGCAAAAGATTAAGATTTTATCTGGGGGAAAGAAAAGAATTTTTTAAAAAATTAAACTAAA
 481 GATGTTTTAAGCTAAAGCCTGAATTTGGGATGGAAGCAGGACAGACACCGTGGACAGCGCTGTATTTACAGACACACCCA
 561 GTGCGTGAAGACCAACAAAGTCACAGTCGTATCTCTAGAAAGCTCTAAAGACCATGTTGGAAAGAGTCTCCAGTTACTGA
 641 ACAGATGAAAAGGAGCCTGTGAGAGGGCTGTTAACATTAGCAAATATTTTTTCCTTGTTTTTTCTTTGTTAAAACCAAAC
 721 TGGTTCACCTGAATCATGAATTGAGAAGAAATAATTTTCATTTCTAAATTAAGTCCCTTTTAGTTTGATCAGACAGCTTG
 801 AATCAGCATCTCTTCTTCCCTGTCAGCCTGACTCTTCCCTTCCCCTCTCTCATTCCCCATACTCCCTATTTTCATTCCTT
 881 TTTTAAAAAATAATATAAGCTACAGAAACCAGGTAAGCCCTTTATTTCCTTAAATGTTTTGCCAGCCACTTACCAATTGC
 961 TAAGTATTGAATTTCAGAAAAAAAAAATGCATTTACTGGCAAGGAGAAGAGCAAAGTTAAGGCTTGATACCAATCGAGCT
1041 AAGGATACCTGCTTTGGAAGCATGTTTATTCTGTTCCCCAGCAACTCTGGCCTCCAAAATGGGAGAAAACGCCAGTGTGT
1121 TTAAATTGATAGCAGATATCACGACAGATTTAACCTCTGCCATGTGTTTTTTATTTTGTTTTTTAGCAGTGCTGACTAAG
1201 CCGAAGTTTTGTAAGGTACATAAAATCCAATTTATATGTAAACAAGCAATAATTTAAGTTGAGAACTTATGTGTTTTAAT
1281 TGTATAATTTTTGTGAGGTATACATATTGTGGAATTGACTCAAAAATGAGGTACTTCAGTATTAAATTAGATATCTTCAT
1361 AGCAATGTCTCCTAAAGGTGTTTTGTAAAGGATATCAATGCCTTGATTAGACCTAATTTGTAGACTTAAGACTTTTTATT
1441 TTCTAAACCTTGTGATTCTGCTTATAAGTCATTTATCTAATCTATATGATATGCAGCCGCTGTAGGAACCAATTCTTGAT
1521 TTTTATATGTTTATATTCTTTCTTAATGAACCTTAGAAAGACTACATGTTACTAAGCAGGCCACTTTTATGGTTGTTTTT
1601 CTTGCCCACTCTGGTAGGGGAAAAATCTTTTATTAATAGGTGTCAGTTTCAGACAACTCCAATACCAAGAAACTGATGAC
1681 CTTTTTTGAGCTATTTCTCCTTAACCCCTAATACCTTTCTTACCTAAATTTCAGAATGATATCTTTTTGATGTCTAAAAA
1761 GCAAAGCATTTTATAATATCTCATTAGCCAGGCTTTTTAGGAACAGAGAAGTTTTTCCTTGAAATTTGATTGTTTGTTTA
1841 TTTGTGGCAGGGTGAAAAATGTACAAACTACCCCTATTTATACTTATATCTCTCTCTATATGTACGCATTATGGAAATAT
1921 AGGAAGAGATATAGCCCAAAGATAGATGGTAAGTAGACAGTCTGAAAATGTTGCTCCATACTAAAGAACCTTTCTGGAAA
2001 TTTGCATTTCGCTACTTTTTTCCACTTGAGAGGGGTCTCAATACAGGGAGGTGGCCAAGGAACAACACTTCTCAGTGGCC
2081 ACCAGTTCATATATCCCCTCAAAAGGCTCTACTTTTCTCCACCAAACCATTGGGTTGCCCAACTGTGATGGAAAAAACAA
2161 GCAGATGTTGGCCCAGAACTCCAGGACCTCCCCGTGGGCTGAGGCTCATGTGGCATACAATTCAGTGTGACCAGTTTTAA
2241 TGTTCAGAAATATGTGAATTAGAATGACTTTTAACTTCACACAGCACAAAAGAGAAATGGAGTTTAAACTGGATTTGTTT
2321 TGTTTTGAGTTTCAAGTCCCTTTTCACTACAACACCGTCCAAAACTATCTACCTATCTCTTCTTTTTTATCCATCTGCCC
2401 GCTGTATTTTAATGTCAATCCTAATTCAGACAAATCCGCAACTTCATGATACTGGTAATTTATAATAATTCGTGATCATT
2481 GCTGTTTTGAAGGAAAAGAGATGATAAATTCTCTTACGGTTTCAATCAGGTAATGGATTTTGTTTTACATCTAGTTAGGA
2561 GAAGAAAAGTAAGTGAAGGAATCCTCTGATCATATTGATCACTATAGAAGCAAAAGCCAAATCAGTTCCCTTCATTATCA
2641 GTATTTCTCATGCTGTACACAATAAATTTGTTAGACTGAGTACTTGGTTTTTGTTTAATAGAACAAATAATCAGTGTTTC
2721 ACTTATATTACTAAATGTGAAAAACATAATGTGAAAAGTATACATACATTAACTTGGTTGTAAAACTCATTTTAAGTGTT
2801 CATGTAATGTGGTAAGTTTAAAAAGTGAAGTGAGCTGTTTTACTACAATGAATTCGTTTGACTCAAAGATTAAAATGCCC
2881 CTCCCCCTATGTGTATCTCTTATGGCCTGTAATAATTGAAAGCAATGTTTTTGCAGTTTATATAATGCAATTTTTAATCT
2961 GTGTTCAAAAATGGAGTTCATATGGGCTTAACACATGAAATGGGTGGCACAGATCCACTTGCAGAACCCAAAGATACACA
3041 ATCAGTTTTGAAATGCAACTTAAGCCATTAATTGTTGGTGTGAATTTAAAATTTTCTAGTGTTTGTATGGTGGTATGCTG
3121 CCTAAGAGCAAAGCATCCTCTGCACAAAAGAAAATTACTGTAGTGGCTTCGATTTTAATTAGAATTTTCTCCCTGGTGTT
3201 TCTTTATAGACTAAAGCAAAATCTTTTAAGTTTCTTACTACAGGTAAAAGCTATGTGCAAGAACCTCAAAATGCTAAAAT
3281 CTAGCATAATGCCTTAGATCTGTTTTTAAGTCTTGTATATTCCTACATAGCTGTCCGATGTATTATATTTGTATAGTGAA
3361 TTGTGTACAATTTTTGAATAAGTGCATCATCACTTAACCTTTATGTTGTTTGAATAGTGATGATGATACATTTCTTCAGA
3441 CATTTAACTGTCATTTTTTTCCTTTGTCATTTGTGAGTTTTATTTGTACAGTTCCTCATGAAGTTGCATCTGAGATGTGT
3521 GTATATGAAAAGATTATACAAGGGTAAAATTAAGCAATATATTAACTATGGTTCTTCAGGAGAAAGCTTACAGTGTTTCA
3601 GGTTGTGATTTATTTTCAAAATGGAGTTGACTCTGAACATCACTTTGTTCACCTGCATTGATGTTTGTATTTCTAGTGTG
3681 AGCAGTTTATGCAAAGGTAGATATATTCAGAGAAATTTTAAATACATTTATGCAAGTTAATATTGCTTTGCTGATGCTAT
3761 TTGCTTATTTGATGTTAAATAATGCTATTGTAAATAAAGAATTCTGTTGTTATTGCATCATTTAATAAATTTTAATGCCT
3841 TCGGGTTTTACATGGCTTTAGAGATTTTAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuugaacgauuuuuACGUCUUa 5'
                        ||||||| 
Target 5' ggcacagatccactTGCAGAAc 3'
 3006 - 3027 140.00 -5.94
2 
miRNA  3' cuUGAACGAUU------UUUACGUCUUa 5'
            | |||||||      || | ||||| 
Target 5' ccAATTGCTAAGTATTGAATTTCAGAAa 3'
 953 - 980 134.00 -9.40
3 
miRNA  3' cuuGAACGAUUUUUACGUCUUa 5'
             ||| |  ||| | ||||| 
Target 5' tttCTTACCTAAATTTCAGAAt 3'
 1716 - 1737 131.00 -7.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30162047 11 COSMIC
COSN1367724 28 COSMIC
COSN24388430 44 COSMIC
COSN30104522 99 COSMIC
COSN30721671 99 COSMIC
COSN30104519 103 COSMIC
COSN30131271 133 COSMIC
COSN30648612 152 COSMIC
COSN26440182 182 COSMIC
COSN31528227 328 COSMIC
COSN30164396 421 COSMIC
COSN31548269 427 COSMIC
COSN31548290 440 COSMIC
COSN28740462 491 COSMIC
COSN29550059 818 COSMIC
COSN2287404 1138 COSMIC
COSN17825860 1250 COSMIC
COSN9268305 1269 COSMIC
COSN9268304 1270 COSMIC
COSN31529828 1425 COSMIC
COSN42885 2192 COSMIC
COSN20326876 2212 COSMIC
COSN8098745 2401 COSMIC
COSN22576703 2489 COSMIC
COSN5687168 2820 COSMIC
COSN16426215 2968 COSMIC
COSN25793955 3003 COSMIC
COSN9667580 3206 COSMIC
COSN15051663 3408 COSMIC
COSN26839634 3517 COSMIC
COSN8860350 3577 COSMIC
COSN26129038 3838 COSMIC
COSN26697429 3842 COSMIC
rs118135766 2478 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs368655450 2 dbSNP
rs1300376831 3 dbSNP
rs978416691 5 dbSNP
rs1229774811 12 dbSNP
rs774471025 19 dbSNP
rs774821713 28 dbSNP
rs76809412 33 dbSNP
rs1359908490 34 dbSNP
rs1312531458 38 dbSNP
rs1482291345 52 dbSNP
rs913011200 53 dbSNP
rs528705643 55 dbSNP
rs1160296669 62 dbSNP
rs960182788 72 dbSNP
rs1382494546 73 dbSNP
rs1367434307 75 dbSNP
rs1421142324 78 dbSNP
rs371386462 78 dbSNP
rs1358091953 80 dbSNP
rs1162224696 82 dbSNP
rs1304550671 91 dbSNP
rs1475954800 99 dbSNP
rs559655668 101 dbSNP
rs369583274 105 dbSNP
rs954630795 107 dbSNP
rs150911442 108 dbSNP
rs1488206479 109 dbSNP
rs1224567580 124 dbSNP
rs1278161151 126 dbSNP
rs996146738 131 dbSNP
rs1023623931 135 dbSNP
rs1244358901 139 dbSNP
rs1177242765 140 dbSNP
rs1457721342 140 dbSNP
rs777333052 151 dbSNP
rs375227603 152 dbSNP
rs1046009 153 dbSNP
rs891995232 154 dbSNP
rs1057326439 158 dbSNP
rs1003001687 160 dbSNP
rs373048452 161 dbSNP
rs1025773998 162 dbSNP
rs1378903285 167 dbSNP
rs1044639435 168 dbSNP
rs906000400 173 dbSNP
rs1337155241 176 dbSNP
rs947739656 177 dbSNP
rs994256170 181 dbSNP
rs527903292 186 dbSNP
rs1221098780 189 dbSNP
rs1399160952 192 dbSNP
rs1263836446 197 dbSNP
rs184747219 199 dbSNP
rs901304696 204 dbSNP
rs1197324122 206 dbSNP
rs920255426 207 dbSNP
rs1438793353 210 dbSNP
rs752270117 215 dbSNP
rs565504552 220 dbSNP
rs940460991 221 dbSNP
rs1389948525 225 dbSNP
rs1476841925 226 dbSNP
rs907578652 233 dbSNP
rs1007529708 243 dbSNP
rs890067561 258 dbSNP
rs1063099 269 dbSNP
rs1042691421 279 dbSNP
rs987285816 281 dbSNP
rs1429410769 291 dbSNP
rs1464631836 302 dbSNP
rs1168497342 308 dbSNP
rs954518034 310 dbSNP
rs947085952 320 dbSNP
rs912978486 328 dbSNP
rs1347834801 330 dbSNP
rs969165908 332 dbSNP
rs1284103991 335 dbSNP
rs1340000580 349 dbSNP
rs778160608 353 dbSNP
rs1169588416 354 dbSNP
rs545157998 359 dbSNP
rs1052763099 364 dbSNP
rs938450591 368 dbSNP
rs928435916 370 dbSNP
rs1340655712 371 dbSNP
rs1371739592 379 dbSNP
rs1288210986 382 dbSNP
rs1403092194 384 dbSNP
rs1195817948 392 dbSNP
rs769363061 395 dbSNP
rs1269119620 397 dbSNP
rs192418277 404 dbSNP
rs576523711 413 dbSNP
rs1374236540 417 dbSNP
rs1475703620 419 dbSNP
rs1211828462 424 dbSNP
rs774542614 434 dbSNP
rs956149449 436 dbSNP
rs1426290029 438 dbSNP
rs1469934874 440 dbSNP
rs1304020785 445 dbSNP
rs1360124006 447 dbSNP
rs747692711 454 dbSNP
rs1398286394 456 dbSNP
rs879578460 460 dbSNP
rs556138253 464 dbSNP
rs186479445 465 dbSNP
rs1227901450 468 dbSNP
rs1282924086 481 dbSNP
rs1330380226 483 dbSNP
rs1323883807 492 dbSNP
rs560052159 499 dbSNP
rs984119200 508 dbSNP
rs865979725 510 dbSNP
rs574353736 512 dbSNP
rs1292127953 513 dbSNP
rs554463891 529 dbSNP
rs375507772 530 dbSNP
rs995770268 537 dbSNP
rs898859904 538 dbSNP
rs1366611371 539 dbSNP
rs1037375184 542 dbSNP
rs1163964607 544 dbSNP
rs372538219 551 dbSNP
rs1379387475 555 dbSNP
rs1418100517 559 dbSNP
rs1160467215 563 dbSNP
rs994632260 565 dbSNP
rs1332849018 568 dbSNP
rs965508026 572 dbSNP
rs933180271 584 dbSNP
rs1046013 585 dbSNP
rs974667649 588 dbSNP
rs1237537258 589 dbSNP
rs754729028 595 dbSNP
rs751305164 598 dbSNP
rs1475950346 606 dbSNP
rs1254063590 607 dbSNP
rs1377557770 607 dbSNP
rs1237370468 621 dbSNP
rs1437570895 627 dbSNP
rs1192369273 630 dbSNP
rs1007087674 638 dbSNP
rs779956053 641 dbSNP
rs1465658941 643 dbSNP
rs914433100 657 dbSNP
rs1408308345 659 dbSNP
rs1455626428 667 dbSNP
rs1331204552 676 dbSNP
rs1375207413 678 dbSNP
rs1393469679 685 dbSNP
rs558755572 691 dbSNP
rs1308780557 694 dbSNP
rs375314078 695 dbSNP
rs1231999310 704 dbSNP
rs988844771 704 dbSNP
rs1253742510 707 dbSNP
rs140931008 710 dbSNP
rs367553006 712 dbSNP
rs1275385839 720 dbSNP
rs1257314612 725 dbSNP
rs1035804453 728 dbSNP
rs981505438 735 dbSNP
rs970253481 736 dbSNP
rs1023130459 747 dbSNP
rs1196977530 773 dbSNP
rs996040273 775 dbSNP
rs1480791466 778 dbSNP
rs1011784462 783 dbSNP
rs891427226 787 dbSNP
rs1016232600 793 dbSNP
rs1463903047 807 dbSNP
rs1004581846 819 dbSNP
rs750307947 821 dbSNP
rs933065712 822 dbSNP
rs1236452239 828 dbSNP
rs74776423 838 dbSNP
rs1316005864 844 dbSNP
rs1307831987 845 dbSNP
rs1439414649 851 dbSNP
rs563045601 857 dbSNP
rs1038867299 858 dbSNP
rs1271278426 869 dbSNP
rs1295378834 871 dbSNP
rs928434534 884 dbSNP
rs1421495970 885 dbSNP
rs760693264 889 dbSNP
rs1430809695 896 dbSNP
rs948621717 912 dbSNP
rs1456688846 914 dbSNP
rs909049452 914 dbSNP
rs1172281756 917 dbSNP
rs1367041937 925 dbSNP
rs984671837 935 dbSNP
rs1405121225 941 dbSNP
rs549757712 944 dbSNP
rs1297048006 948 dbSNP
rs3088092 951 dbSNP
rs934671145 953 dbSNP
rs1296181964 962 dbSNP
rs1178022074 972 dbSNP
rs1468726541 974 dbSNP
rs1234799749 975 dbSNP
rs1182856399 976 dbSNP
rs1441600777 977 dbSNP
rs1277873823 978 dbSNP
rs767692832 985 dbSNP
rs1294295552 988 dbSNP
rs139564184 988 dbSNP
rs928615505 988 dbSNP
rs1486860224 990 dbSNP
rs567932662 990 dbSNP
rs965832277 991 dbSNP
rs1019729755 995 dbSNP
rs546312028 996 dbSNP
rs1348427211 1004 dbSNP
rs113815273 1011 dbSNP
rs1023032302 1012 dbSNP
rs1221571575 1013 dbSNP
rs1386181609 1015 dbSNP
rs954170721 1016 dbSNP
rs528024845 1024 dbSNP
rs1157626232 1027 dbSNP
rs183280455 1033 dbSNP
rs1279748932 1034 dbSNP
rs1289440751 1035 dbSNP
rs974281178 1036 dbSNP
rs1011753589 1038 dbSNP
rs759871471 1052 dbSNP
rs892072324 1053 dbSNP
rs1239721482 1058 dbSNP
rs1031742556 1062 dbSNP
rs1318884447 1068 dbSNP
rs1002579699 1071 dbSNP
rs906946470 1078 dbSNP
rs1255433905 1084 dbSNP
rs774568842 1099 dbSNP
rs1376586938 1110 dbSNP
rs1244155447 1111 dbSNP
rs545632654 1136 dbSNP
rs950422161 1139 dbSNP
rs1029963983 1141 dbSNP
rs531649184 1142 dbSNP
rs887582749 1143 dbSNP
rs1410309110 1150 dbSNP
rs1159213104 1153 dbSNP
rs1159251017 1154 dbSNP
rs1048944963 1155 dbSNP
rs929189398 1161 dbSNP
rs1338565463 1170 dbSNP
rs562655837 1178 dbSNP
rs1255684228 1181 dbSNP
rs1278062911 1182 dbSNP
rs900276714 1198 dbSNP
rs1039162719 1202 dbSNP
rs1011436809 1203 dbSNP
rs192672135 1210 dbSNP
rs35415150 1211 dbSNP
rs892941406 1227 dbSNP
rs1053080337 1229 dbSNP
rs973136282 1234 dbSNP
rs944091512 1237 dbSNP
rs1234900763 1240 dbSNP
rs928502448 1242 dbSNP
rs1227267950 1246 dbSNP
rs912554049 1252 dbSNP
rs1332143235 1254 dbSNP
rs761216471 1261 dbSNP
rs985526386 1265 dbSNP
rs948672058 1266 dbSNP
rs76656425 1270 dbSNP
rs1178545249 1277 dbSNP
rs560566638 1282 dbSNP
rs1356553874 1284 dbSNP
rs1021723656 1288 dbSNP
rs990308246 1293 dbSNP
rs1464987267 1304 dbSNP
rs956284301 1319 dbSNP
rs974546043 1321 dbSNP
rs540956554 1351 dbSNP
rs1274464956 1353 dbSNP
rs908697802 1353 dbSNP
rs982939826 1354 dbSNP
rs1284546385 1369 dbSNP
rs1317853408 1370 dbSNP
rs1003541649 1371 dbSNP
rs1275588981 1380 dbSNP
rs1460988207 1399 dbSNP
rs1415951958 1401 dbSNP
rs1167447124 1402 dbSNP
rs906835497 1404 dbSNP
rs764287334 1406 dbSNP
rs1204832235 1412 dbSNP
rs1023066896 1425 dbSNP
rs1029844027 1428 dbSNP
rs1200978735 1430 dbSNP
rs1418579068 1435 dbSNP
rs866505101 1436 dbSNP
rs1416356219 1438 dbSNP
rs997149835 1438 dbSNP
rs887550288 1460 dbSNP
rs1166038523 1461 dbSNP
rs572351471 1462 dbSNP
rs1486780586 1465 dbSNP
rs1048910958 1468 dbSNP
rs763236179 1469 dbSNP
rs1242649361 1471 dbSNP
rs897733695 1475 dbSNP
rs1040249510 1478 dbSNP
rs1466794230 1479 dbSNP
rs1363927471 1482 dbSNP
rs115532784 1484 dbSNP
rs1011738015 1485 dbSNP
rs893003594 1488 dbSNP
rs538835330 1489 dbSNP
rs576172804 1491 dbSNP
rs60220895 1492 dbSNP
rs1272407313 1494 dbSNP
rs773664028 1498 dbSNP
rs747641890 1499 dbSNP
rs1356833471 1504 dbSNP
rs907132201 1505 dbSNP
rs1269009809 1512 dbSNP
rs914693981 1524 dbSNP
rs1445896811 1526 dbSNP
rs763323406 1533 dbSNP
rs1364615034 1538 dbSNP
rs1271356185 1542 dbSNP
rs956170263 1548 dbSNP
rs1162709383 1566 dbSNP
rs924782146 1567 dbSNP
rs981689117 1568 dbSNP
rs1440246118 1570 dbSNP
rs948724878 1577 dbSNP
rs972076411 1578 dbSNP
rs1022612414 1581 dbSNP
rs1327516472 1589 dbSNP
rs780914724 1590 dbSNP
rs1385380751 1591 dbSNP
rs1012616215 1598 dbSNP
rs200546685 1604 dbSNP
rs1349415508 1605 dbSNP
rs1202843489 1611 dbSNP
rs1038488824 1617 dbSNP
rs1354190708 1619 dbSNP
rs1182868150 1622 dbSNP
rs1241063090 1624 dbSNP
rs941451103 1626 dbSNP
rs951766149 1627 dbSNP
rs558907001 1630 dbSNP
rs982933749 1635 dbSNP
rs1451789271 1638 dbSNP
rs1160379809 1640 dbSNP
rs187651541 1652 dbSNP
rs955507902 1654 dbSNP
rs1335296348 1662 dbSNP
rs922882943 1663 dbSNP
rs975616690 1666 dbSNP
rs1192982061 1672 dbSNP
rs964447659 1673 dbSNP
rs1027445473 1678 dbSNP
rs1236344899 1682 dbSNP
rs1350700560 1705 dbSNP
rs1213794791 1710 dbSNP
rs1480073652 1715 dbSNP
rs1203008359 1725 dbSNP
rs1261143150 1738 dbSNP
rs1462538067 1739 dbSNP
rs993249066 1743 dbSNP
rs1017678952 1749 dbSNP
rs1417592623 1749 dbSNP
rs1309694622 1752 dbSNP
rs897621995 1754 dbSNP
rs989797973 1761 dbSNP
rs957351192 1766 dbSNP
rs1040622270 1771 dbSNP
rs1408928091 1779 dbSNP
rs567255686 1779 dbSNP
rs1234255746 1787 dbSNP
rs768020508 1789 dbSNP
rs1369470524 1794 dbSNP
rs1394729974 1800 dbSNP
rs182997102 1804 dbSNP
rs1031390248 1806 dbSNP
rs1330442301 1808 dbSNP
rs998716883 1812 dbSNP
rs907017670 1817 dbSNP
rs1024268191 1818 dbSNP
rs3750200 1833 dbSNP
rs767841068 1840 dbSNP
rs889053580 1841 dbSNP
rs1250572288 1843 dbSNP
rs191681576 1846 dbSNP
rs1297414962 1853 dbSNP
rs1372793303 1856 dbSNP
rs1296723156 1861 dbSNP
rs1197818789 1865 dbSNP
rs932696162 1866 dbSNP
rs551645718 1868 dbSNP
rs186447339 1869 dbSNP
rs370471367 1872 dbSNP
rs562767784 1876 dbSNP
rs1354933056 1886 dbSNP
rs1197382858 1887 dbSNP
rs934758663 1887 dbSNP
rs887201368 1888 dbSNP
rs1047120561 1890 dbSNP
rs934182327 1896 dbSNP
rs922768862 1898 dbSNP
rs746614358 1899 dbSNP
rs1169353493 1900 dbSNP
rs1370771644 1901 dbSNP
rs1396827177 1902 dbSNP
rs975669327 1905 dbSNP
rs143990323 1906 dbSNP
rs529386312 1908 dbSNP
rs183072717 1911 dbSNP
rs915456561 1917 dbSNP
rs971660644 1920 dbSNP
rs368112025 1928 dbSNP
rs990240999 1932 dbSNP
rs374209511 1934 dbSNP
rs1252941405 1939 dbSNP
rs745667834 1943 dbSNP
rs1220481437 1946 dbSNP
rs1271164253 1957 dbSNP
rs1490526834 1969 dbSNP
rs991149909 1970 dbSNP
rs1260255262 1973 dbSNP
rs768814053 1974 dbSNP
rs749519174 1977 dbSNP
rs1384926002 1978 dbSNP
rs951653778 1980 dbSNP
rs148124670 1986 dbSNP
rs993216297 1989 dbSNP
rs2954728 2001 dbSNP
rs1161260068 2003 dbSNP
rs962117847 2010 dbSNP
rs1018760911 2011 dbSNP
rs894403064 2017 dbSNP
rs1288279292 2034 dbSNP
rs1235112867 2035 dbSNP
rs1016825327 2037 dbSNP
rs1009181924 2039 dbSNP
rs889038341 2040 dbSNP
rs1050267206 2041 dbSNP
rs572205713 2050 dbSNP
rs1381706960 2061 dbSNP
rs1393315950 2073 dbSNP
rs893110467 2077 dbSNP
rs1322471368 2095 dbSNP
rs1269708964 2115 dbSNP
rs1215140302 2119 dbSNP
rs887095271 2120 dbSNP
rs1487138965 2124 dbSNP
rs144724083 2130 dbSNP
rs1242975159 2142 dbSNP
rs934067784 2144 dbSNP
rs901231401 2145 dbSNP
rs1386694458 2152 dbSNP
rs1423976413 2178 dbSNP
rs1412707018 2193 dbSNP
rs1342890483 2194 dbSNP
rs545196210 2198 dbSNP
rs1039850877 2203 dbSNP
rs934745622 2207 dbSNP
rs1405129439 2209 dbSNP
rs1450173440 2225 dbSNP
rs915507789 2230 dbSNP
rs924720036 2232 dbSNP
rs370884707 2234 dbSNP
rs1304995055 2245 dbSNP
rs950302650 2249 dbSNP
rs916083919 2253 dbSNP
rs1263059621 2258 dbSNP
rs991706360 2261 dbSNP
rs149357732 2262 dbSNP
rs1205986315 2264 dbSNP
rs920232759 2269 dbSNP
rs971744911 2270 dbSNP
rs971140727 2273 dbSNP
rs1405222369 2280 dbSNP
rs916980973 2284 dbSNP
rs1160696014 2289 dbSNP
rs1159901326 2298 dbSNP
rs1428497422 2299 dbSNP
rs1468113705 2300 dbSNP
rs961806200 2309 dbSNP
rs1019150639 2312 dbSNP
rs536345912 2317 dbSNP
rs573829111 2324 dbSNP
rs991747029 2325 dbSNP
rs1017286148 2328 dbSNP
rs958551163 2328 dbSNP
rs1229068392 2332 dbSNP
rs1419252477 2338 dbSNP
rs1256389655 2340 dbSNP
rs1225852873 2345 dbSNP
rs1279812552 2347 dbSNP
rs1187602116 2349 dbSNP
rs1203425375 2349 dbSNP
rs987242165 2351 dbSNP
rs755030087 2352 dbSNP
rs1028799315 2356 dbSNP
rs553445186 2357 dbSNP
rs1425660853 2372 dbSNP
rs901283828 2372 dbSNP
rs1258984688 2375 dbSNP
rs1241291242 2377 dbSNP
rs1356508009 2378 dbSNP
rs1330012364 2381 dbSNP
rs1010754493 2382 dbSNP
rs893748486 2393 dbSNP
rs533795998 2400 dbSNP
rs1032962915 2401 dbSNP
rs571817924 2415 dbSNP
rs751742222 2418 dbSNP
rs999296446 2419 dbSNP
rs1275926009 2420 dbSNP
rs1339209932 2422 dbSNP
rs766540598 2433 dbSNP
rs763328895 2437 dbSNP
rs950171605 2438 dbSNP
rs1205379608 2439 dbSNP
rs894617410 2446 dbSNP
rs1055989360 2460 dbSNP
rs138693819 2471 dbSNP
rs924151949 2472 dbSNP
rs118135766 2478 dbSNP
rs377656055 2492 dbSNP
rs557988159 2501 dbSNP
rs569098036 2504 dbSNP
rs1391747564 2509 dbSNP
rs1430673890 2512 dbSNP
rs1363837075 2513 dbSNP
rs1382726835 2517 dbSNP
rs1426618650 2517 dbSNP
rs940313099 2518 dbSNP
rs949674250 2523 dbSNP
rs549210214 2525 dbSNP
rs917035121 2533 dbSNP
rs1290575930 2534 dbSNP
rs1356720016 2537 dbSNP
rs991237699 2548 dbSNP
rs1289889447 2550 dbSNP
rs958828739 2553 dbSNP
rs911571456 2554 dbSNP
rs1213501827 2560 dbSNP
rs868085978 2561 dbSNP
rs1249715309 2585 dbSNP
rs987600289 2586 dbSNP
rs1162426234 2588 dbSNP
rs1449816430 2588 dbSNP
rs1183288804 2592 dbSNP
rs1383601168 2595 dbSNP
rs1474411432 2602 dbSNP
rs1473863077 2610 dbSNP
rs1420419673 2612 dbSNP
rs60168250 2615 dbSNP
rs1320821001 2618 dbSNP
rs1428377806 2625 dbSNP
rs879794482 2628 dbSNP
rs951303812 2629 dbSNP
rs777513763 2631 dbSNP
rs758415072 2634 dbSNP
rs560644931 2637 dbSNP
rs1294979235 2641 dbSNP
rs1284304873 2646 dbSNP
rs998154662 2650 dbSNP
rs546642842 2651 dbSNP
rs1272755906 2658 dbSNP
rs965331909 2658 dbSNP
rs1465224696 2661 dbSNP
rs1018813867 2668 dbSNP
rs1240964954 2670 dbSNP
rs533384870 2674 dbSNP
rs762466273 2680 dbSNP
rs1188448315 2681 dbSNP
rs893848552 2683 dbSNP
rs1468639157 2691 dbSNP
rs777289872 2708 dbSNP
rs1413365916 2709 dbSNP
rs145577001 2714 dbSNP
rs1469679176 2714 dbSNP
rs999450587 2715 dbSNP
rs1397470096 2720 dbSNP
rs371441589 2722 dbSNP
rs999669896 2725 dbSNP
rs1334731908 2736 dbSNP
rs1236232274 2742 dbSNP
rs1289613743 2743 dbSNP
rs1329778022 2746 dbSNP
rs150161670 2749 dbSNP
rs768145747 2754 dbSNP
rs796854682 2762 dbSNP
rs1201285792 2767 dbSNP
rs746531847 2773 dbSNP
rs190816479 2779 dbSNP
rs1184444673 2796 dbSNP
rs1480410241 2802 dbSNP
rs1174878962 2803 dbSNP
rs916919061 2803 dbSNP
rs1466874931 2811 dbSNP
rs531679911 2823 dbSNP
rs1323342579 2837 dbSNP
rs1367625735 2839 dbSNP
rs775155010 2848 dbSNP
rs1395337161 2852 dbSNP
rs1407538553 2855 dbSNP
rs562671261 2856 dbSNP
rs1394775995 2859 dbSNP
rs771668250 2878 dbSNP
rs532497307 2881 dbSNP
rs1164128346 2883 dbSNP
rs185468465 2884 dbSNP
rs909584706 2886 dbSNP
rs764902518 2889 dbSNP
rs1475330487 2890 dbSNP
rs1250485731 2895 dbSNP
rs1337734475 2896 dbSNP
rs1207502484 2901 dbSNP
rs573616464 2907 dbSNP
rs929782742 2912 dbSNP
rs918532032 2920 dbSNP
rs1196016828 2922 dbSNP
rs1490198981 2923 dbSNP
rs1197976072 2925 dbSNP
rs1450133474 2937 dbSNP
rs553849990 2942 dbSNP
rs1252412519 2948 dbSNP
rs180865680 2950 dbSNP
rs899336130 2951 dbSNP
rs1018283104 2961 dbSNP
rs1371656477 2967 dbSNP
rs1036989650 2969 dbSNP
rs940968281 2971 dbSNP
rs1469945005 2974 dbSNP
rs1290870356 2975 dbSNP
rs1195010438 2978 dbSNP
rs958165882 2979 dbSNP
rs911526789 2981 dbSNP
rs563715117 2997 dbSNP
rs1291773475 2998 dbSNP
rs1032810126 3004 dbSNP
rs1387238757 3012 dbSNP
rs754657653 3013 dbSNP
rs189580981 3017 dbSNP
rs1294613669 3022 dbSNP
rs999720951 3023 dbSNP
rs1051463114 3044 dbSNP
rs902662399 3054 dbSNP
rs1298605310 3058 dbSNP
rs1358893842 3064 dbSNP
rs1220374057 3067 dbSNP
rs1267225282 3072 dbSNP
rs1337275097 3079 dbSNP
rs56181957 3082 dbSNP
rs1025272578 3083 dbSNP
rs931720444 3090 dbSNP
rs1205005926 3091 dbSNP
rs1013839238 3100 dbSNP
rs1451681310 3110 dbSNP
rs1190184077 3126 dbSNP
rs1370184887 3129 dbSNP
rs1129100 3138 dbSNP
rs1390388634 3145 dbSNP
rs921720446 3146 dbSNP
rs1443562211 3151 dbSNP
rs1162127626 3170 dbSNP
rs757175542 3171 dbSNP
rs557369312 3178 dbSNP
rs1288188208 3184 dbSNP
rs1386272383 3193 dbSNP
rs1436996353 3195 dbSNP
rs1320917129 3196 dbSNP
rs1382311094 3205 dbSNP
rs543845585 3206 dbSNP
rs1327837289 3209 dbSNP
rs186394005 3210 dbSNP
rs1314964402 3212 dbSNP
rs957827259 3213 dbSNP
rs1409726206 3223 dbSNP
rs936980940 3230 dbSNP
rs923804680 3239 dbSNP
rs1266775375 3241 dbSNP
rs978384838 3269 dbSNP
rs1394831519 3274 dbSNP
rs749169044 3280 dbSNP
rs1170039842 3281 dbSNP
rs1242878515 3308 dbSNP
rs1430903765 3317 dbSNP
rs569211456 3320 dbSNP
rs1179732440 3324 dbSNP
rs777695262 3326 dbSNP
rs1014283411 3332 dbSNP
rs1048119475 3335 dbSNP
rs755049688 3336 dbSNP
rs1034396904 3337 dbSNP
rs929851189 3342 dbSNP
rs994932891 3345 dbSNP
rs1446150266 3349 dbSNP
rs1304775625 3350 dbSNP
rs1380062304 3353 dbSNP
rs1461239979 3363 dbSNP
rs1390876968 3366 dbSNP
rs899305136 3368 dbSNP
rs1331882087 3372 dbSNP
rs1036553908 3378 dbSNP
rs1435838055 3379 dbSNP
rs943960072 3380 dbSNP
rs1207672531 3385 dbSNP
rs911105173 3396 dbSNP
rs1176133762 3398 dbSNP
rs985488998 3403 dbSNP
rs1473542916 3404 dbSNP
rs1159781010 3406 dbSNP
rs1428383002 3413 dbSNP
rs1005528032 3417 dbSNP
rs1252341238 3418 dbSNP
rs890743461 3420 dbSNP
rs141804907 3426 dbSNP
rs1346972039 3428 dbSNP
rs1359977328 3429 dbSNP
rs1461611161 3443 dbSNP
rs1306285677 3450 dbSNP
rs879309098 3452 dbSNP
rs931689408 3455 dbSNP
rs1235833083 3456 dbSNP
rs1411017621 3459 dbSNP
rs780466307 3461 dbSNP
rs921604656 3462 dbSNP
rs78216254 3466 dbSNP
rs978171025 3466 dbSNP
rs1279704658 3468 dbSNP
rs1312446753 3473 dbSNP
rs1203929985 3474 dbSNP
rs1271917545 3485 dbSNP
rs1278558454 3493 dbSNP
rs1182888584 3495 dbSNP
rs936437431 3498 dbSNP
rs1476966977 3516 dbSNP
rs923746496 3523 dbSNP
rs1025157087 3527 dbSNP
rs977975040 3532 dbSNP
rs971036925 3535 dbSNP
rs917874204 3537 dbSNP
rs1372563259 3538 dbSNP
rs1430475911 3547 dbSNP
rs895419530 3549 dbSNP
rs1034319020 3555 dbSNP
rs756371984 3558 dbSNP
rs766602378 3561 dbSNP
rs958663137 3563 dbSNP
rs566824972 3568 dbSNP
rs1361668315 3571 dbSNP
rs1227260871 3591 dbSNP
rs1426015188 3591 dbSNP
rs1158088573 3592 dbSNP
rs1034364462 3602 dbSNP
rs1048166300 3606 dbSNP
rs1288441827 3618 dbSNP
rs547050033 3619 dbSNP
rs929735153 3623 dbSNP
rs1182621690 3641 dbSNP
rs1223645718 3643 dbSNP
rs896870358 3643 dbSNP
rs1448641278 3657 dbSNP
rs533300116 3678 dbSNP
rs1186974348 3712 dbSNP
rs1392273870 3720 dbSNP
rs1450256492 3725 dbSNP
rs1485254726 3728 dbSNP
rs570817888 3736 dbSNP
rs994900232 3744 dbSNP
rs1255289591 3745 dbSNP
rs963518244 3746 dbSNP
rs60063828 3752 dbSNP
rs531591403 3759 dbSNP
rs890701871 3769 dbSNP
rs1282882394 3773 dbSNP
rs911167978 3778 dbSNP
rs1221590025 3783 dbSNP
rs1366921924 3785 dbSNP
rs1051983732 3791 dbSNP
rs996390770 3799 dbSNP
rs543847581 3801 dbSNP
rs1283143311 3802 dbSNP
rs1353608198 3806 dbSNP
rs1288665642 3812 dbSNP
rs900147136 3813 dbSNP
rs1053401468 3820 dbSNP
rs1050087268 3827 dbSNP
rs936403258 3830 dbSNP
rs1464344374 3835 dbSNP
rs902289085 3842 dbSNP
rs1042605629 3843 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions islets
Tools used in this research TargetScan
Original Description (Extracted from the article) ... HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO. ...

- Kameswaran V; Bramswig NC; McKenna LB; Penn et al., 2014, Cell metabolism.

Article - Kameswaran V; Bramswig NC; McKenna LB; Penn et al.
- Cell metabolism, 2014
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing beta cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To determine if microRNAs are involved in the pathogenesis of human T2DM, we sequenced the small RNAs of human islets from diabetic and nondiabetic organ donors. We identified a cluster of microRNAs in an imprinted locus on human chromosome 14q32 that is highly and specifically expressed in human beta cells and dramatically downregulated in islets from T2DM organ donors. The downregulation of this locus strongly correlates with hypermethylation of its promoter. Using HITS-CLIP for the essential RISC-component Argonaute, we identified disease-relevant targets of the chromosome 14q32 microRNAs, such as IAPP and TP53INP1, that cause increased beta cell apoptosis upon overexpression in human islets. Our results support a role for microRNAs and their epigenetic control by DNA methylation in the pathogenesis of T2DM.
LinkOut: [PMID: 24374217]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
139 hsa-miR-544a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT053511 BMI1 BMI1 proto-oncogene, polycomb ring finger 4 1
MIRT054802 CDH1 cadherin 1 3 2
MIRT075814 ZCCHC14 zinc finger CCHC-type containing 14 2 3
MIRT125570 SCD stearoyl-CoA desaturase 1 1
MIRT246745 SF1 splicing factor 1 2 2
MIRT259487 TXLNG taxilin gamma 2 2
MIRT307650 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 2 2
MIRT377046 ASXL2 additional sex combs like 2, transcriptional regulator 2 2
MIRT386936 STAT3 signal transducer and activator of transcription 3 3 1
MIRT394127 UBQLN1 ubiquilin 1 1 1
MIRT439199 ZNF483 zinc finger protein 483 1 1
MIRT439207 ZNF33A zinc finger protein 33A 1 1
MIRT439262 ZBTB17 zinc finger and BTB domain containing 17 1 1
MIRT439263 YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma 1 1
MIRT439281 XAB2 XPA binding protein 2 1 1
MIRT439314 VAT1 vesicle amine transport 1 1 1
MIRT439380 TTC37 tetratricopeptide repeat domain 37 1 1
MIRT439397 TPT1 tumor protein, translationally-controlled 1 1 1
MIRT439419 TMOD1 tropomodulin 1 1 1
MIRT439491 SYT5 synaptotagmin 5 1 1
MIRT439511 STXBP1 syntaxin binding protein 1 1 1
MIRT439586 SMAD7 SMAD family member 7 1 1
MIRT439727 RPS6 ribosomal protein S6 1 1
MIRT439768 RLIM ring finger protein, LIM domain interacting 1 1
MIRT439828 RAD50 RAD50 double strand break repair protein 1 1
MIRT439840 RAB21 RAB21, member RAS oncogene family 1 1
MIRT439846 RAB14 RAB14, member RAS oncogene family 1 1
MIRT439975 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha 1 1
MIRT440031 PCDHAC2 protocadherin alpha subfamily C, 2 1 1
MIRT440135 NCOA2 nuclear receptor coactivator 2 1 1
MIRT440173 MTSS1L MTSS1L, I-BAR domain containing 1 1
MIRT440222 MMP2 matrix metallopeptidase 2 1 1
MIRT440433 IQGAP1 IQ motif containing GTPase activating protein 1 1 1
MIRT440443 INTS3 integrator complex subunit 3 1 1
MIRT440449 INS insulin 1 1
MIRT440512 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1 1
MIRT440534 GPR56 adhesion G protein-coupled receptor G1 1 1
MIRT440540 GOLGB1 golgin B1 1 1
MIRT440580 GEM GTP binding protein overexpressed in skeletal muscle 1 1
MIRT440629 FNDC3A fibronectin type III domain containing 3A 1 1
MIRT440667 FBXL16 F-box and leucine rich repeat protein 16 1 1
MIRT440680 CCSER1 coiled-coil serine rich protein 1 1 1
MIRT440696 FADS1 fatty acid desaturase 1 1 1
MIRT440761 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 1 1
MIRT440764 DUSP26 dual specificity phosphatase 26 1 1
MIRT440769 DSTYK dual serine/threonine and tyrosine protein kinase 1 1
MIRT440774 DSP desmoplakin 1 1
MIRT440792 DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 1 1
MIRT440801 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 1 1
MIRT440888 CPE carboxypeptidase E 1 1
MIRT440923 CLTC clathrin heavy chain 1 1
MIRT440950 CHD7 chromodomain helicase DNA binding protein 7 1 1
MIRT440993 CC2D2A coiled-coil and C2 domain containing 2A 1 1
MIRT441014 CAPN3 calpain 3 1 1
MIRT441106 BRD4 bromodomain containing 4 1 1
MIRT441144 ATP6V1B2 ATPase H+ transporting V1 subunit B2 1 1
MIRT441173 ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1 1
MIRT441258 ADM adrenomedullin 1 1
MIRT441279 ACTB actin beta 2 5
MIRT441298 ACACB acetyl-CoA carboxylase beta 1 1
MIRT443751 SLC7A14 solute carrier family 7 member 14 2 2
MIRT450469 TRMT5 tRNA methyltransferase 5 2 4
MIRT450852 HMGN2 high mobility group nucleosomal binding domain 2 2 6
MIRT454152 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT465705 TNFAIP1 TNF alpha induced protein 1 2 2
MIRT466121 TMEM170A transmembrane protein 170A 2 2
MIRT471376 PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2 2
MIRT477475 ELL2 elongation factor for RNA polymerase II 2 2 2
MIRT481660 ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2 2
MIRT502469 FAM98A family with sequence similarity 98 member A 2 8
MIRT503952 ZNF180 zinc finger protein 180 2 6
MIRT505585 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 6
MIRT529936 SYNGR1 synaptogyrin 1 2 2
MIRT530626 PPIC peptidylprolyl isomerase C 2 4
MIRT536883 HIC2 HIC ZBTB transcriptional repressor 2 2 2
MIRT546847 RAB1A RAB1A, member RAS oncogene family 2 2
MIRT548448 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT557130 HOXA13 homeobox A13 2 2
MIRT560089 ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2 2
MIRT560984 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT566340 POLDIP2 DNA polymerase delta interacting protein 2 2 2
MIRT567838 DCAF8 DDB1 and CUL4 associated factor 8 2 2
MIRT609236 SERPINA4 serpin family A member 4 2 2
MIRT611452 ZWILCH zwilch kinetochore protein 2 2
MIRT612058 PDGFRA platelet derived growth factor receptor alpha 2 2
MIRT612783 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 4
MIRT615116 BCL11B B-cell CLL/lymphoma 11B 2 2
MIRT616572 C1orf56 chromosome 1 open reading frame 56 2 2
MIRT616690 LPL lipoprotein lipase 2 2
MIRT616986 COL19A1 collagen type XIX alpha 1 chain 2 2
MIRT619427 CYB5R3 cytochrome b5 reductase 3 2 2
MIRT623320 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT626897 MON1B MON1 homolog B, secretory trafficking associated 2 2
MIRT637554 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT639473 SLC6A4 solute carrier family 6 member 4 2 2
MIRT639753 GPR45 G protein-coupled receptor 45 2 2
MIRT640703 MRS2 MRS2, magnesium transporter 2 2
MIRT642489 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT644578 SPOP speckle type BTB/POZ protein 2 2
MIRT645009 NGRN neugrin, neurite outgrowth associated 2 2
MIRT646533 KLK2 kallikrein related peptidase 2 2 2
MIRT648625 LEMD2 LEM domain containing 2 2 2
MIRT650235 ERI1 exoribonuclease 1 2 2
MIRT651932 UBN1 ubinuclein 1 2 2
MIRT652960 SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2 2
MIRT654842 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT656142 MSH5 mutS homolog 5 2 2
MIRT656730 LMBRD2 LMBR1 domain containing 2 2 2
MIRT657340 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 2
MIRT658991 DLGAP2 DLG associated protein 2 2 2
MIRT660714 AMER1 APC membrane recruitment protein 1 2 2
MIRT666591 RFX3 regulatory factor X3 2 2
MIRT667201 NKX2-3 NK2 homeobox 3 2 2
MIRT668732 DIO2 iodothyronine deiodinase 2 2 2
MIRT669479 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT681083 GSTO2 glutathione S-transferase omega 2 2 2
MIRT686736 STX16 syntaxin 16 2 2
MIRT687432 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT689887 SOD2 superoxide dismutase 2 2 2
MIRT695759 WDR35 WD repeat domain 35 2 2
MIRT698346 TMEM127 transmembrane protein 127 2 2
MIRT702752 IGF1R insulin like growth factor 1 receptor 2 2
MIRT703137 GPR137C G protein-coupled receptor 137C 2 2
MIRT705063 C4orf32 family with sequence similarity 241 member A 2 2
MIRT709597 IFT74 intraflagellar transport 74 2 2
MIRT709997 TXNDC12 thioredoxin domain containing 12 2 2
MIRT710463 ASTN2 astrotactin 2 2 2
MIRT710468 CDH5 cadherin 5 2 2
MIRT715625 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT720091 SPTLC3 serine palmitoyltransferase long chain base subunit 3 2 2
MIRT721054 DCC DCC netrin 1 receptor 2 2
MIRT721961 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT722122 EPB41 erythrocyte membrane protein band 4.1 2 2
MIRT722538 AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2 2
MIRT723325 DGAT1 diacylglycerol O-acyltransferase 1 2 2
MIRT725330 NEUROD1 neuronal differentiation 1 2 2
MIRT731556 HOXA10 homeobox A10 2 1
MIRT732380 BCL6 B-cell CLL/lymphoma 6 3 1
MIRT736700 E2F5 E2F transcription factor 5 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-544a Cisplatin 5460033 NSC119875 approved sensitive Low Esophageal Squamous Cell Carcinoma cell line (KYSE450, TE-1)
hsa-miR-544a Trastuzumab sensitive High Breast Cancer cell line (SKBR3)
hsa-mir-544a Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-544a Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-544a Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-544a Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-544a Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-544a Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-544a Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-miR-544a Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-544a Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-544a Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-miR-544a Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-544a Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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