miRTarBase - #MIRT441872


—
pre-miRNA Information
pre-miRNA hsa-mir-4786   
Genomic Coordinates chr2: 239943015 - 239943094
Description Homo sapiens miR-4786 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4786-3p
Sequence 51| UGAAGCCAGCUCUGGUCUGGGC |72
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs765116255 2 dbSNP
rs982109365 6 dbSNP
rs949249229 7 dbSNP
rs759383793 8 dbSNP
rs990649205 9 dbSNP
rs1389629709 14 dbSNP
rs975346189 18 dbSNP
rs188625223 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PPP1R15B   
Synonyms CREP, MSSGM2
Description protein phosphatase 1 regulatory subunit 15B
Transcript NM_032833   
Expression
Putative miRNA Targets on PPP1R15B
3'UTR of PPP1R15B
(miRNA target sites are highlighted)		 
>PPP1R15B|NM_032833|3'UTR
   1 GTTGGCAGCCTGTAGTCCTAGCTAGCATACACTACCTCTTACCTGAGAGGTGTCTTTTAAAAACAAATCTTGGCAGCTGT
  81 CCTTTGACATTTTTTTTTTTAGAGGAAATGTAACTTGGATCTAGTTTAATTTTTTTTTTTGCAACATATCCCACTCAGAA
 161 ACATTCAGGTTTGAAGCCAGCCCTGATAATGAAGGATGAACTAGTGTGATTTCTAATCCTCCCTTTTTTGATTTAGTTGG
 241 ATGTGCTTTTAAATGTCCTTTGCCTGCATGAGGTGGAAAGGGGACCTTTTTGAGTTGTCATTTTGCACTTTCAAAACTTA
 321 TTTTCTTGGAAAACAATATTTATAGGGCTTAAAGCCCATTTTCATTTCTAATCTAAATTATGTGTGCCTATCTGAAAACT
 401 TTGGGCTCTTTCTTGTTTCTTTCCCAAAATTCAGAAGTTAATGGGCTTTTATGTTTTTCTATATTTTTTTTATTTCAATG
 481 ATTTGGCCTGTCTATGTTAGGCTAAAAAATAACCTTGTGTATGCTACCAACTTAAAGTGCATTATTTTGTGTCACTTTTT
 561 TTTTTCTTGTAAAAATGACTTGGATTGAAAATATGTGGTAGCCTTTTTATTTCTACATTAAGTTCTACCTAGGATATTTC
 641 CAAGGACTGCCACAAAACCCATATGTGCAGTACTTTACTACTTTGGGAAAGCTGCATCTTTCTACCACATTTTAACATCT
 721 AATATATTTAATTTCTTTGAAGAGGGTTCTGTGTACGTTATTGTAGTTCCCAGTTTAATATAGTTCTTTGTATCTCTTAA
 801 CAGGTTGAAGTTATTGCAAAACACTCTGGAAAGTAATAATTACATCATAATCATTTATTTTTTAAACTTAAAAGCCTAGA
 881 AATTTCCTAGAAAGAAAATAGGAGACATCTCAGAGCAATTTGGTTTTGGTGTATATGTTCTCAACAGAAAACCAGTGTTA
 961 ATGAATATCATGCCTCAGCACTGTCACTTTTAAAACCTGTCAGGATCCCACTGTAAAATTGGAAATGGGCAGTTCTGAAT
1041 TTTCACGTTTGAAATGTAAAATATAAACTTCAGTCAATATCCAGGTTTATTGTGTCCTACTATTTAATAATGAGAGAAGT
1121 AATGGCAAGGCCTTTACTTTCAGGAAAGGATAGAAGTATAGATTAATGACTGGAAAGTTTTAATATATTTAGCCCAAAGG
1201 TTACTTTGAATTGAAGTCTTTGCATTGACTGTTTGTGTTTGGTTTATTTGTTTAGCTTTACAAGGTACACATAAGTTAGG
1281 TTGAGGGGTTGTTAACCCTTCCGTGGTCTGCTTTCATTCCGTGTGCTTCCTGTCACAGGTAATGGAAAACATAAGTAGAA
1361 TAGGTGACCTCTTAGTTTTGAACTTATTTAAGTGTGGGGATGAATTTTTCATCAGAAGTGCTTACAGGGTTACTACCTCA
1441 GTTTACAATCTACCTGGTCATTATTTTATTTCTATCCAGTTCTAAGAACTGCCTCCACTGTTTATATATTCATAATTAAA
1521 CACATTGAGAATGCAACACTATAAAAGCTGGTCAAATTTTTGCAGAGCCCTTATTCTGTGTGTTTTTTGTTTTTTTCTTT
1601 TTTTTTTGAGACAGAGTCTCGTTCGGTCCCCCAGCTTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTC
1681 CTGGGTTCACGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACACACCACCACGCCCGGCTAATTTT
1761 TTGTGTCTTTTTAGTAGAGACGGGGTTTCGCTATGTTGGCCAGACTGGTCTTGAACTGCTGACCTCGTGATCCGCCCGCC
1841 TCGGCCTCTCAAAGTGCTGGGATTCTGTGTGTTTTGTGCACCTCCACTTTAGGTAATCATAGGGAGCACATTTACAGGAT
1921 GGTCTAATAACATGAAAACAGGCTAGTTTCAAGCAACAGCAATGTCGGTTGGAAAGCAGGCGTCATTTGCCTTGAAAAAA
2001 GCCTTTTGACAACATACAGGCATTCTTTTAAAACCAGGCTGAAACATTTTATTTCCGAGACTTAACGTTGTGTTTCCTGT
2081 TTCTTAAACCTAGCACCTCTGTGTATTTGAAAATAATGAGACATCTTTCATTGGATTTTGGAAAATTGTTCCCCATGGGA
2161 TTCTAACCTCACTACCAAATGAGTGAAAGCTTGATTAAGAGTTCTTCCATATACTAGCCTCCTTGGAAGAAGTGATCAGA
2241 AGGTGATAAGAAGGACAGAAAGGACTATTTTAAAGTTGGACTGAAGGAGAAAAAAGCAAAATTCTTGTTTCATCCCAATT
2321 CTAGTTAGAACAAAGTTAAACCCCCGTAATCTTAAAGAGAAAATCTTTGGAGGTTTTAATTAAACATTTTATACATTTAA
2401 AGTCTTGTTAATGGTGCTTTAAGTGTCAATGTAGCATGTAAAAGGCTTTGTACAGACAGGTAAAAGTTCCATTTCTGAGT
2481 GATGAAATGTAACACTTCTTCATCTTTAACTTGAAATCAAAACTATCAGATTTTATTTTTGTATAATTTAAGGAAGGTAA
2561 AGTTAGGGGACTAGAAGACTCTAAATTGGCTTCTACAGATCAATAATTTAAATGTAACTAGTTGGGATTTTATAGTTAAA
2641 ATTATATTTGTGTATATAACATAACTAATCTGTAAATTGTAATAAATATATTTGCAATTATTAAATGTTAAGTGATATTT
2721 TGGTTCAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgggUCUG-GUCUCGACCGAAGu 5'
              |||| |  | :||||||| 
Target 5' tagaAGACTCTAAATTGGCTTCt 3'
 2572 - 2594 154.00 -14.50
2 
miRNA  3' cgGGUCUGGUCUCGACCGAAGu 5'
            :|||| || | :|||:||: 
Target 5' tcTCAGAGCA-ATTTGGTTTTg 3'
 908 - 928 131.00 -16.30
3 
miRNA  3' cggguCUGGUCUCGACC-GAAgu 5'
               |:||||| |||| |||  
Target 5' atgttGGCCAGA-CTGGTCTTga 3'
 1793 - 1814 116.00 -17.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26990095 3 COSMIC
COSN26990094 16 COSMIC
COSN30162502 45 COSMIC
COSN30489387 81 COSMIC
COSN1427323 90 COSMIC
COSN18725366 107 COSMIC
COSN20074009 129 COSMIC
COSN27304530 129 COSMIC
COSN510167 130 COSMIC
COSN18714312 142 COSMIC
COSN20073925 151 COSMIC
COSN6019660 195 COSMIC
COSN25851497 517 COSMIC
COSN27582217 555 COSMIC
COSN27265644 556 COSMIC
COSN22621225 786 COSMIC
COSN31562555 824 COSMIC
COSN19316043 967 COSMIC
COSN31567701 1049 COSMIC
COSN22848293 1053 COSMIC
COSN31535899 1086 COSMIC
COSN31562065 1180 COSMIC
COSN31532456 1189 COSMIC
COSN31536088 1201 COSMIC
COSN26329169 1208 COSMIC
COSN31480575 1213 COSMIC
COSN31562067 1266 COSMIC
COSN24298115 1428 COSMIC
COSN26548523 1495 COSMIC
COSN31565736 1557 COSMIC
COSN29653646 1597 COSMIC
COSN15926212 1982 COSMIC
COSN32065429 2077 COSMIC
COSN21464391 2242 COSMIC
COSN31582923 2446 COSMIC
COSN20095842 2505 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs766116914 1 dbSNP
rs760341612 4 dbSNP
rs1480853614 5 dbSNP
rs1271170786 16 dbSNP
rs772789323 18 dbSNP
rs770942204 20 dbSNP
rs1183773221 22 dbSNP
rs771597286 30 dbSNP
rs572514186 31 dbSNP
rs773865460 35 dbSNP
rs749827590 37 dbSNP
rs959487040 38 dbSNP
rs780437646 40 dbSNP
rs1260050277 41 dbSNP
rs749819237 41 dbSNP
rs756488617 42 dbSNP
rs1484883954 43 dbSNP
rs746092967 44 dbSNP
rs781333131 50 dbSNP
rs892935886 50 dbSNP
rs1052965743 64 dbSNP
rs747588810 65 dbSNP
rs1490541575 67 dbSNP
rs1198923660 82 dbSNP
rs1267091118 89 dbSNP
rs1473766113 90 dbSNP
rs1282860371 101 dbSNP
rs375282063 101 dbSNP
rs1360522218 104 dbSNP
rs1452183680 107 dbSNP
rs1035069797 127 dbSNP
rs1270071698 128 dbSNP
rs1365606336 141 dbSNP
rs1403830319 141 dbSNP
rs374844400 141 dbSNP
rs879796050 141 dbSNP
rs148060364 151 dbSNP
rs966693409 152 dbSNP
rs112614284 163 dbSNP
rs772838912 168 dbSNP
rs1311118744 180 dbSNP
rs1021598797 185 dbSNP
rs184365286 186 dbSNP
rs893950288 190 dbSNP
rs1306100653 191 dbSNP
rs1316819834 204 dbSNP
rs1028523273 209 dbSNP
rs1314912358 217 dbSNP
rs1246824229 218 dbSNP
rs997022572 227 dbSNP
rs900892009 234 dbSNP
rs1174050922 237 dbSNP
rs75289486 240 dbSNP
rs1221911969 250 dbSNP
rs1040830608 255 dbSNP
rs985637000 263 dbSNP
rs1455374653 264 dbSNP
rs1178002351 270 dbSNP
rs1250188889 306 dbSNP
rs952971197 310 dbSNP
rs114722944 312 dbSNP
rs1386452010 320 dbSNP
rs1185927603 323 dbSNP
rs1161193373 328 dbSNP
rs1372013362 336 dbSNP
rs972963696 337 dbSNP
rs961739799 342 dbSNP
rs1370861518 344 dbSNP
rs886802500 363 dbSNP
rs1397607826 384 dbSNP
rs115979358 390 dbSNP
rs931279628 392 dbSNP
rs1208062168 399 dbSNP
rs1003384827 401 dbSNP
rs1289599356 402 dbSNP
rs1309350400 405 dbSNP
rs915727075 406 dbSNP
rs991242401 407 dbSNP
rs938526215 408 dbSNP
rs115521069 409 dbSNP
rs114453171 410 dbSNP
rs1213490139 411 dbSNP
rs1306184737 412 dbSNP
rs1011466473 419 dbSNP
rs1244276938 419 dbSNP
rs11240739 423 dbSNP
rs1182288782 424 dbSNP
rs913930377 437 dbSNP
rs1292763425 439 dbSNP
rs1053361091 441 dbSNP
rs998727576 461 dbSNP
rs1169275020 464 dbSNP
rs1352454716 465 dbSNP
rs1040099797 472 dbSNP
rs200915717 472 dbSNP
rs901685807 472 dbSNP
rs1405091424 488 dbSNP
rs1450286426 494 dbSNP
rs191944426 494 dbSNP
rs1215281231 495 dbSNP
rs1364657173 499 dbSNP
rs1295096072 514 dbSNP
rs1306040501 517 dbSNP
rs958276999 518 dbSNP
rs565782250 519 dbSNP
rs996989931 525 dbSNP
rs143841933 537 dbSNP
rs551956592 537 dbSNP
rs112018878 539 dbSNP
rs1314927833 548 dbSNP
rs569582886 564 dbSNP
rs1416947043 566 dbSNP
rs551600593 566 dbSNP
rs931561635 566 dbSNP
rs920211182 568 dbSNP
rs1169459843 569 dbSNP
rs549354880 572 dbSNP
rs374973311 591 dbSNP
rs1468069516 594 dbSNP
rs961539809 594 dbSNP
rs1425638805 610 dbSNP
rs1185194358 612 dbSNP
rs750214584 613 dbSNP
rs530369513 616 dbSNP
rs1288433627 621 dbSNP
rs1048099050 622 dbSNP
rs1359955206 623 dbSNP
rs115008171 627 dbSNP
rs981512349 631 dbSNP
rs111886051 632 dbSNP
rs1222121344 633 dbSNP
rs749121392 634 dbSNP
rs938493531 653 dbSNP
rs1239803800 654 dbSNP
rs928492400 660 dbSNP
rs1189694398 661 dbSNP
rs1199645961 661 dbSNP
rs541244082 665 dbSNP
rs1031558442 667 dbSNP
rs1408620321 670 dbSNP
rs1399972784 677 dbSNP
rs527855344 682 dbSNP
rs1232701047 703 dbSNP
rs1040617696 704 dbSNP
rs371981428 704 dbSNP
rs1345181556 717 dbSNP
rs1403491785 721 dbSNP
rs779899972 724 dbSNP
rs913887263 725 dbSNP
rs1048691191 735 dbSNP
rs1374525347 735 dbSNP
rs1360939636 736 dbSNP
rs1222645412 738 dbSNP
rs545206906 753 dbSNP
rs1290562353 756 dbSNP
rs1489757767 757 dbSNP
rs576472920 761 dbSNP
rs1309804058 762 dbSNP
rs1233182002 763 dbSNP
rs1469454785 769 dbSNP
rs1175367980 770 dbSNP
rs1271757319 777 dbSNP
rs1415921222 778 dbSNP
rs930338918 781 dbSNP
rs376693260 786 dbSNP
rs1232756737 796 dbSNP
rs1335627614 801 dbSNP
rs918933374 805 dbSNP
rs556642385 810 dbSNP
rs568090090 812 dbSNP
rs940272218 814 dbSNP
rs1389939875 818 dbSNP
rs373233773 819 dbSNP
rs928787932 824 dbSNP
rs1297426933 830 dbSNP
rs1442606230 832 dbSNP
rs1402393669 841 dbSNP
rs1162625899 842 dbSNP
rs117124850 850 dbSNP
rs1385695081 853 dbSNP
rs1246065572 856 dbSNP
rs1418006306 876 dbSNP
rs970127788 882 dbSNP
rs1197127257 889 dbSNP
rs1273306451 892 dbSNP
rs1166246309 893 dbSNP
rs1416966096 899 dbSNP
rs1406741431 901 dbSNP
rs1178145483 903 dbSNP
rs921494190 904 dbSNP
rs1481790532 905 dbSNP
rs183997344 915 dbSNP
rs990245249 916 dbSNP
rs957369534 921 dbSNP
rs1213694362 922 dbSNP
rs1032092254 933 dbSNP
rs1469279502 941 dbSNP
rs1397546859 944 dbSNP
rs965523500 955 dbSNP
rs1019828837 966 dbSNP
rs977330678 967 dbSNP
rs966388938 973 dbSNP
rs1004367599 977 dbSNP
rs1018774811 984 dbSNP
rs376875330 987 dbSNP
rs1336675456 996 dbSNP
rs951124372 1001 dbSNP
rs1007370119 1011 dbSNP
rs1236909802 1012 dbSNP
rs1229025333 1018 dbSNP
rs1027157654 1019 dbSNP
rs1307888374 1026 dbSNP
rs1338424666 1027 dbSNP
rs1212449000 1035 dbSNP
rs547924138 1039 dbSNP
rs1264710764 1046 dbSNP
rs888849980 1047 dbSNP
rs193235516 1058 dbSNP
rs1241246252 1063 dbSNP
rs894151017 1072 dbSNP
rs1323612224 1073 dbSNP
rs1440148519 1082 dbSNP
rs1055618847 1094 dbSNP
rs534838206 1097 dbSNP
rs897452374 1099 dbSNP
rs1168806327 1100 dbSNP
rs1294808059 1102 dbSNP
rs763390640 1103 dbSNP
rs1431835444 1110 dbSNP
rs187730109 1112 dbSNP
rs1362878561 1113 dbSNP
rs558700179 1114 dbSNP
rs1383398963 1116 dbSNP
rs1318333963 1120 dbSNP
rs1325362957 1123 dbSNP
rs1428157751 1124 dbSNP
rs141450239 1125 dbSNP
rs1393699679 1129 dbSNP
rs529749673 1130 dbSNP
rs1323957717 1131 dbSNP
rs1222725150 1136 dbSNP
rs569405413 1145 dbSNP
rs1455101499 1150 dbSNP
rs1352830838 1151 dbSNP
rs113151027 1157 dbSNP
rs1262442814 1158 dbSNP
rs913960217 1162 dbSNP
rs1191727880 1163 dbSNP
rs1485549596 1180 dbSNP
rs916098795 1183 dbSNP
rs553233861 1186 dbSNP
rs1054301053 1187 dbSNP
rs990192818 1191 dbSNP
rs936091416 1192 dbSNP
rs1376289365 1196 dbSNP
rs1345969416 1197 dbSNP
rs924626542 1204 dbSNP
rs1383565969 1224 dbSNP
rs977861847 1232 dbSNP
rs1304562490 1235 dbSNP
rs776896560 1237 dbSNP
rs1404108800 1249 dbSNP
rs1281062440 1253 dbSNP
rs1233246235 1263 dbSNP
rs779567288 1272 dbSNP
rs936669091 1280 dbSNP
rs1303247095 1281 dbSNP
rs1260101737 1282 dbSNP
rs921295082 1286 dbSNP
rs975655066 1292 dbSNP
rs986022556 1296 dbSNP
rs1294200282 1299 dbSNP
rs1490593448 1301 dbSNP
rs147763520 1302 dbSNP
rs912821918 1303 dbSNP
rs1363778640 1312 dbSNP
rs745469306 1315 dbSNP
rs1437265934 1317 dbSNP
rs982936624 1320 dbSNP
rs182279720 1321 dbSNP
rs994514250 1337 dbSNP
rs758538671 1351 dbSNP
rs1014588948 1355 dbSNP
rs1435653606 1364 dbSNP
rs1391797212 1369 dbSNP
rs73061876 1384 dbSNP
rs1374647239 1387 dbSNP
rs1238050279 1388 dbSNP
rs1317179148 1390 dbSNP
rs1360287525 1393 dbSNP
rs1221973806 1394 dbSNP
rs1026711827 1395 dbSNP
rs974253388 1402 dbSNP
rs1481813299 1406 dbSNP
rs1196806450 1413 dbSNP
rs1428432462 1425 dbSNP
rs1250432153 1428 dbSNP
rs1262582879 1435 dbSNP
rs1195878497 1444 dbSNP
rs190263769 1448 dbSNP
rs1034008455 1450 dbSNP
rs1443511120 1454 dbSNP
rs1162217670 1466 dbSNP
rs1484833783 1467 dbSNP
rs1374484664 1472 dbSNP
rs1279802562 1474 dbSNP
rs948951779 1476 dbSNP
rs894614194 1493 dbSNP
rs1397851910 1495 dbSNP
rs1209909387 1496 dbSNP
rs375843884 1498 dbSNP
rs1345524008 1533 dbSNP
rs1257538107 1534 dbSNP
rs1002741958 1536 dbSNP
rs1337347703 1539 dbSNP
rs936095390 1541 dbSNP
rs907088367 1548 dbSNP
rs924711723 1548 dbSNP
rs977433761 1549 dbSNP
rs535129013 1555 dbSNP
rs1401258230 1569 dbSNP
rs1353183050 1570 dbSNP
rs1311834942 1574 dbSNP
rs1206075413 1586 dbSNP
rs1244335247 1589 dbSNP
rs535009045 1596 dbSNP
rs1263402379 1608 dbSNP
rs34231967 1608 dbSNP
rs12091367 1611 dbSNP
rs892985470 1614 dbSNP
rs1421159364 1616 dbSNP
rs773199565 1617 dbSNP
rs531715764 1620 dbSNP
rs777134255 1621 dbSNP
rs185551487 1624 dbSNP
rs1301098540 1625 dbSNP
rs1053864624 1628 dbSNP
rs1382939269 1632 dbSNP
rs1277835990 1637 dbSNP
rs1225784596 1639 dbSNP
rs1264286107 1645 dbSNP
rs936785535 1651 dbSNP
rs899830890 1652 dbSNP
rs1039687955 1653 dbSNP
rs944028197 1658 dbSNP
rs1185542742 1659 dbSNP
rs912789449 1666 dbSNP
rs1481288403 1667 dbSNP
rs372910081 1672 dbSNP
rs1172917627 1673 dbSNP
rs930141709 1675 dbSNP
rs920116721 1679 dbSNP
rs1454405827 1680 dbSNP
rs1297794320 1690 dbSNP
rs1256884266 1691 dbSNP
rs973839416 1692 dbSNP
rs570810919 1693 dbSNP
rs1217938373 1702 dbSNP
rs566320271 1714 dbSNP
rs1444311522 1715 dbSNP
rs1283438266 1716 dbSNP
rs973683230 1718 dbSNP
rs1015117858 1725 dbSNP
rs1193808949 1727 dbSNP
rs958485097 1733 dbSNP
rs1034063933 1737 dbSNP
rs981038173 1739 dbSNP
rs1419730436 1741 dbSNP
rs1158195099 1746 dbSNP
rs552538616 1748 dbSNP
rs1020184722 1750 dbSNP
rs574054621 1751 dbSNP
rs532738524 1752 dbSNP
rs1332102910 1753 dbSNP
rs1434825960 1756 dbSNP
rs766910613 1763 dbSNP
rs1240070545 1768 dbSNP
rs1292123675 1773 dbSNP
rs1306388500 1773 dbSNP
rs1010600963 1776 dbSNP
rs564663671 1781 dbSNP
rs1415056736 1782 dbSNP
rs894767894 1785 dbSNP
rs554185117 1789 dbSNP
rs1327310387 1790 dbSNP
rs1391117793 1793 dbSNP
rs1397856343 1794 dbSNP
rs1457213146 1794 dbSNP
rs761237970 1795 dbSNP
rs113697838 1820 dbSNP
rs996014680 1826 dbSNP
rs1040094294 1831 dbSNP
rs899884497 1833 dbSNP
rs1413417578 1834 dbSNP
rs572293700 1837 dbSNP
rs1473910494 1838 dbSNP
rs1362236095 1841 dbSNP
rs943995361 1842 dbSNP
rs558516064 1843 dbSNP
rs1384321676 1844 dbSNP
rs191480799 1846 dbSNP
rs903362109 1848 dbSNP
rs1042169006 1852 dbSNP
rs1047296281 1862 dbSNP
rs1353898000 1862 dbSNP
rs930252610 1866 dbSNP
rs1238544882 1871 dbSNP
rs549849826 1874 dbSNP
rs1200522158 1876 dbSNP
rs1467057422 1881 dbSNP
rs944812731 1886 dbSNP
rs186880287 1890 dbSNP
rs1196632835 1891 dbSNP
rs1244948036 1893 dbSNP
rs911861393 1899 dbSNP
rs920100145 1901 dbSNP
rs1236981940 1914 dbSNP
rs1471901767 1927 dbSNP
rs1169894750 1942 dbSNP
rs1424741754 1949 dbSNP
rs1169129443 1950 dbSNP
rs575751222 1950 dbSNP
rs1409015148 1958 dbSNP
rs555813805 1961 dbSNP
rs1050422198 1962 dbSNP
rs535922557 1966 dbSNP
rs566959838 1967 dbSNP
rs1270440380 1968 dbSNP
rs1339573119 1980 dbSNP
rs1216633518 1981 dbSNP
rs931900279 1982 dbSNP
rs747711743 1987 dbSNP
rs1277352821 1999 dbSNP
rs1237864062 2001 dbSNP
rs1199819828 2002 dbSNP
rs1277947256 2003 dbSNP
rs1378203728 2004 dbSNP
rs1440804351 2011 dbSNP
rs927024239 2012 dbSNP
rs1477689752 2013 dbSNP
rs1192032683 2016 dbSNP
rs920535924 2017 dbSNP
rs1466950785 2025 dbSNP
rs1333751465 2027 dbSNP
rs1439405266 2034 dbSNP
rs1172525253 2035 dbSNP
rs981182066 2036 dbSNP
rs373598825 2041 dbSNP
rs971026688 2052 dbSNP
rs114365725 2056 dbSNP
rs149054339 2066 dbSNP
rs768358741 2067 dbSNP
rs1284898241 2073 dbSNP
rs530100705 2092 dbSNP
rs982233315 2095 dbSNP
rs970498927 2096 dbSNP
rs1342936364 2105 dbSNP
rs1207027862 2109 dbSNP
rs749004580 2125 dbSNP
rs964557513 2129 dbSNP
rs1470631230 2130 dbSNP
rs1259474120 2131 dbSNP
rs779810049 2144 dbSNP
rs1214738225 2151 dbSNP
rs1271435165 2180 dbSNP
rs1380721300 2197 dbSNP
rs1180248454 2201 dbSNP
rs1018352614 2205 dbSNP
rs1452542876 2209 dbSNP
rs182258094 2209 dbSNP
rs1198739012 2212 dbSNP
rs1008344673 2218 dbSNP
rs1252231726 2219 dbSNP
rs1158656282 2224 dbSNP
rs552370960 2228 dbSNP
rs1023303365 2242 dbSNP
rs891120199 2245 dbSNP
rs958928779 2249 dbSNP
rs1221683290 2252 dbSNP
rs1391149167 2254 dbSNP
rs1386058021 2271 dbSNP
rs755945188 2275 dbSNP
rs1337532849 2280 dbSNP
rs745767253 2282 dbSNP
rs1309994686 2290 dbSNP
rs1353103570 2293 dbSNP
rs994182371 2297 dbSNP
rs1000469019 2306 dbSNP
rs1353945665 2307 dbSNP
rs1488998306 2307 dbSNP
rs757044533 2308 dbSNP
rs1311949164 2312 dbSNP
rs898707688 2315 dbSNP
rs775011552 2316 dbSNP
rs1038601539 2318 dbSNP
rs1440004376 2326 dbSNP
rs1179842545 2328 dbSNP
rs1218489036 2333 dbSNP
rs781130805 2335 dbSNP
rs1165066682 2341 dbSNP
rs1437325314 2341 dbSNP
rs927496092 2342 dbSNP
rs116238168 2345 dbSNP
rs1457210545 2346 dbSNP
rs1291504432 2359 dbSNP
rs890581864 2363 dbSNP
rs531899607 2368 dbSNP
rs1050368137 2372 dbSNP
rs912983975 2373 dbSNP
rs562992054 2386 dbSNP
rs541370250 2405 dbSNP
rs1275897594 2410 dbSNP
rs1444715253 2414 dbSNP
rs932013283 2423 dbSNP
rs957074130 2429 dbSNP
rs925837920 2431 dbSNP
rs1244352280 2434 dbSNP
rs190605670 2435 dbSNP
rs1341952501 2444 dbSNP
rs1199790380 2445 dbSNP
rs1238157654 2450 dbSNP
rs1317686745 2462 dbSNP
rs964526921 2463 dbSNP
rs940624838 2470 dbSNP
rs867353981 2477 dbSNP
rs1401549169 2478 dbSNP
rs907692784 2485 dbSNP
rs752831071 2487 dbSNP
rs1422817456 2501 dbSNP
rs982006594 2502 dbSNP
rs1432573570 2507 dbSNP
rs140665142 2508 dbSNP
rs529389234 2516 dbSNP
rs1169845242 2527 dbSNP
rs1398097774 2529 dbSNP
rs990580263 2530 dbSNP
rs14575 2535 dbSNP
rs1018822911 2543 dbSNP
rs1304601909 2552 dbSNP
rs1380011630 2552 dbSNP
rs1395629850 2559 dbSNP
rs1310900832 2560 dbSNP
rs1191767140 2575 dbSNP
rs1478951979 2579 dbSNP
rs1219698397 2583 dbSNP
rs1239911910 2584 dbSNP
rs1257977333 2586 dbSNP
rs1316519058 2589 dbSNP
rs1206132707 2593 dbSNP
rs1032008021 2601 dbSNP
rs72752051 2603 dbSNP
rs1179717380 2606 dbSNP
rs955600462 2607 dbSNP
rs1263467319 2639 dbSNP
rs1488430500 2644 dbSNP
rs1192584120 2645 dbSNP
rs1287633437 2652 dbSNP
rs1421228904 2656 dbSNP
rs1209190944 2658 dbSNP
rs1025733654 2661 dbSNP
rs559185009 2664 dbSNP
rs1279775490 2665 dbSNP
rs1359785026 2666 dbSNP
rs540615593 2666 dbSNP
rs1465652991 2669 dbSNP
rs1221470548 2670 dbSNP
rs771401523 2674 dbSNP
rs994544224 2679 dbSNP
rs12062484 2687 dbSNP
rs1338925090 2687 dbSNP
rs1400622376 2689 dbSNP
rs72752050 2697 dbSNP
rs778137134 2701 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796040. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgggucuggucucGACCGAAGu 5'
                       :||||||| 
Target 5' -------------UUGGCUUCu 3'
 		1 - 9
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796040
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000367188.4 | 3UTR | UUGGCUUCUACAGAUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
91 hsa-miR-4786-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055412 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT219055 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT247423 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT301990 NUP50 nucleoporin 50 2 4
MIRT344711 ZNF207 zinc finger protein 207 2 2
MIRT409792 FOXO3 forkhead box O3 2 2
MIRT441666 SEPT3 septin 3 2 2
MIRT441708 RP1L1 RP1 like 1 2 2
MIRT441843 SYT11 synaptotagmin 11 2 2
MIRT441862 TEX35 testis expressed 35 2 2
MIRT441872 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT442363 ZC3H12C zinc finger CCCH-type containing 12C 2 2
MIRT442588 HOXD9 homeobox D9 2 2
MIRT442891 RHCG Rh family C glycoprotein 2 2
MIRT443100 RNF20 ring finger protein 20 2 2
MIRT443238 ANKRD26 ankyrin repeat domain 26 2 2
MIRT443611 OR2D2 olfactory receptor family 2 subfamily D member 2 2 2
MIRT443637 ELP6 elongator acetyltransferase complex subunit 6 2 2
MIRT449298 SMIM19 small integral membrane protein 19 2 2
MIRT449581 ZNF510 zinc finger protein 510 2 2
MIRT450699 RORA RAR related orphan receptor A 2 2
MIRT455269 DDX39B DExD-box helicase 39B 2 10
MIRT456608 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT461509 NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2 2
MIRT461710 ZNF426 zinc finger protein 426 2 2
MIRT463760 YPEL2 yippee like 2 2 2
MIRT465221 TRIP10 thyroid hormone receptor interactor 10 2 2
MIRT466648 TAGLN2 transgelin 2 2 2
MIRT473046 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT473184 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 4
MIRT478996 COLGALT1 collagen beta(1-O)galactosyltransferase 1 2 2
MIRT479650 CD4 CD4 molecule 2 2
MIRT480329 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT484162 FAM71B family with sequence similarity 71 member B 2 2
MIRT487586 FAM83H family with sequence similarity 83 member H 2 2
MIRT487598 NKD2 naked cuticle homolog 2 2 4
MIRT494852 ANKRD24 ankyrin repeat domain 24 2 2
MIRT494931 TMEM167A transmembrane protein 167A 2 2
MIRT495227 SIK2 salt inducible kinase 2 2 4
MIRT496088 C17orf85 nuclear cap binding subunit 3 2 2
MIRT496172 RPL35A ribosomal protein L35a 2 4
MIRT496729 GPR180 G protein-coupled receptor 180 2 2
MIRT496786 COL9A2 collagen type IX alpha 2 chain 2 2
MIRT496844 KCNIP2 potassium voltage-gated channel interacting protein 2 2 2
MIRT497924 BTG1 BTG anti-proliferation factor 1 2 2
MIRT512249 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT513269 SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 2 4
MIRT525310 FANCA Fanconi anemia complementation group A 2 4
MIRT525805 SOD2 superoxide dismutase 2 2 2
MIRT526178 HEPH hephaestin 2 2
MIRT530555 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 4
MIRT531431 MPZL3 myelin protein zero like 3 2 2
MIRT531715 TARS threonyl-tRNA synthetase 2 2
MIRT531812 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT536185 MAOB monoamine oxidase B 2 2
MIRT541015 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT544685 ZNF224 zinc finger protein 224 2 4
MIRT560194 CACNG7 calcium voltage-gated channel auxiliary subunit gamma 7 2 2
MIRT560214 SLC7A1 solute carrier family 7 member 1 2 2
MIRT560703 PRPF4B pre-mRNA processing factor 4B 2 2
MIRT561023 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT562249 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT566256 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT610519 HIAT1 major facilitator superfamily domain containing 14A 2 2
MIRT611255 EHD3 EH domain containing 3 2 2
MIRT625352 MGLL monoglyceride lipase 2 2
MIRT633625 R3HDM2 R3H domain containing 2 2 2
MIRT633638 CASC5 kinetochore scaffold 1 2 2
MIRT643514 CCDC115 coiled-coil domain containing 115 2 2
MIRT647629 PELI3 pellino E3 ubiquitin protein ligase family member 3 2 2
MIRT651218 ZNF225 zinc finger protein 225 2 2
MIRT656738 LMBR1L limb development membrane protein 1 like 2 2
MIRT658055 FSD1L fibronectin type III and SPRY domain containing 1 like 2 2
MIRT662937 PSMB2 proteasome subunit beta 2 2 2
MIRT666735 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT667491 MACROD2 MACRO domain containing 2 2 2
MIRT668131 GJD2 gap junction protein delta 2 2 2
MIRT671644 FBXO36 F-box protein 36 2 2
MIRT674924 TRPM6 transient receptor potential cation channel subfamily M member 6 2 2
MIRT704425 CTNNBIP1 catenin beta interacting protein 1 2 2
MIRT709712 DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 2 2
MIRT710068 UBL4A ubiquitin like 4A 2 2
MIRT716227 DGKI diacylglycerol kinase iota 2 2
MIRT716265 TOM1 target of myb1 membrane trafficking protein 2 2
MIRT719906 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT720888 CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2 2
MIRT721388 ATP13A4 ATPase 13A4 2 2
MIRT721938 LGR4 leucine rich repeat containing G protein-coupled receptor 4 2 2
MIRT722947 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 2
MIRT724745 ZNF391 zinc finger protein 391 2 2
MIRT724761 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4786 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4786-3p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780CIS)
hsa-miR-4786-3p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780CP20)
hsa-miR-4786-3p Cisplatin 5460033 NSC119875 approved resistant Low Oral Cancer cell line (CAL-27, HSC3, SCC-25, HOK, SCC-9)
hsa-miR-4786-3p Fluorouracil 3385 NSC19893 approved resistant Low Oral Cancer cell line (CAL-27, HSC3, SCC-25, HOK, SCC-9)
hsa-miR-4786-3p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-4786-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4786-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4786-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-4786-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4786-3p Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-4786-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (CP20)
hsa-miR-4786-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)

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