miRTarBase - #MIRT442155


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pre-miRNA Information
pre-miRNA hsa-mir-4776-1   
Genomic Coordinates chr2: 212926257 - 212926336
Description Homo sapiens miR-4776-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-4776-2   
Genomic Coordinates chr2: 212926257 - 212926336
Description Homo sapiens miR-4776-2 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4776-3p
Sequence 54| CUUGCCAUCCUGGUCCACUGCAU |76
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1350638372 1 dbSNP
rs1220781023 5 dbSNP
rs1269946481 7 dbSNP
rs547466728 10 dbSNP
rs965980067 11 dbSNP
rs953060487 13 dbSNP
rs982906747 14 dbSNP
rs1028686150 21 dbSNP
rs951447113 23 dbSNP
Putative Targets

Gene Information
Gene Symbol DPY19L1   
Synonyms -
Description dpy-19 like C-mannosyltransferase 1
Transcript NM_015283   
Expression
Putative miRNA Targets on DPY19L1
3'UTR of DPY19L1
(miRNA target sites are highlighted)		 
>DPY19L1|NM_015283|3'UTR
   1 CTGCTACATGACCTGCTGCCTACGGAGAACTACATCTGTAATGGTTTTAATGTTTTGCTAAGTCATGTGTTGTTCATATC
  81 CCAAAAACTTTTATAGGTAACTGTTTTCAAATAGAAAACGTTTTATTTGGTCAATTTGAATGTCATTCTAATTATAAAAA
 161 TGACTTACACCTTTATCAATTGGTTACTATTTCAATGCACCCTTTAAAATTTGCTATGCAAATGAGTATATGCTTGTACT
 241 TGACTTTAATATTTGTGCTAAAGTGAGCAAAGCTACCTGTATAAAGAAAACACAGTGGGTTGTGACAAGGATGACATGAA
 321 AATACAGGACAATTCTGACAATGTAGGGGCTGATTTTATAGTGTAAGAACTATTAATGCCCCTTGCTTCTTTTTTCTGCC
 401 TCTTGCTCTTGTCTTTTGGACATTTCAGTGATTGTAAGTTCTTCGGTCATGTCAGCCCCTGTCATCAACTTGAGTTACAG
 481 TAGATGGGGCAGACATGGAGTGTTTGCTATATAGAACTATCTGTTTGTTTTACTTCCTTGTGCGCTTTTTGTTCTCTGTT
 561 CTCTTGTTAATGAAGCTTTTCCTGCCCATTATTAATCCAAACTCTTGGACCTTGTGGTTAGGAAATTCCCTTAACTTCCA
 641 GCCATATGGCATTATCGTGTCTCTTTCTCTCTCTCTCTTGCTCTCTCTCTTCTCCTCTTCCCCATATTTTCTGTCAAATA
 721 AGTACTGTTTACTCATTTAGTTGCTTATCAAGTACTTATTCTTGGTTTTAAAAAAAATTAATGGTAACTGTATTTTTCTC
 801 ATTTTTAGCATTATTCAAATGTTTATATTTTAATACCTTTAAACCACTTTAAAGTTTTTTCATGTTTAATTATAGTTTTA
 881 AGAAAAACTATTTTGAACAACCCCAAATATAGTGCATCTAGAAACTAATGTATATTTGATTAGACATCATTTATAGTGGA
 961 ACAGTAGACTGTAGTACATGGTAATTTTTCTTTTACTATTAAGATACAATAAAACATGACTAATTTTGCTGTCAAAAATG
1041 TAAAGAATAATGATAAATGGAGTTTTTATATTTTACTTTTAAGATTGCCTGTCTTTAATAAGACAAAGCCTTAAGCCTTA
1121 TGTTATAATTTTGGTTCTAAAAACCATCATTTCAGTATAAGGAATAAGTATATTTCGTCCTCCTCTTTAGTTTTTTTCTT
1201 CCTATTTATTTTTATTTTGAAAAATTTCTACACCTTCTTTGAATTCCTTGTATGAATTTTTGTTTCTTAGAAGTTAATTT
1281 GTGTGAAATGAGATTCTTCAAAACGATGAAACCTCATAGCTCTGAGAAAAGGTTTTAGGGTTTTAAATTCTAAGCAAAGC
1361 GTGACTATGGCTGACAGACTACACATTTAATTATACAGCTTCTCTTTCTTAACCACAGGCAGATTAACCTCATTGTGGAT
1441 TGTCCTTCAGACCTTAGTCCTCAGGCATGGTTTCTGGTGCCCACTCCTGGAAGCCGCTGTTCCCTTTCTACCTTCTTACC
1521 AGAGCCCAAGGGCAGGCCTGGTCCCGGGGAAGCAGCAGCTTGCTGACATAAGTCAGCTGCAAAGGCTGAGGAGTGTGCCC
1601 TCAGAGAAGCACCGCCCCCCAGTCTTGTGCCAGCGCCTAGAGCCGCAGCTCCCAGGGATGCTCCTTCCCTGGAGGCAGCC
1681 CAGGAGAGGGACTCTGGCAGCGTTCTTCAGATTTGTGGCCACTGTTTCTCATTTGCTGGTTGACTGTTTTTATTTCTTAG
1761 GCTTTTGCTAGTTTTAGAAAATAGGGAAGCAGCCCTTGATTTGTGGATTAAAAGCAACATTTGAGCGATGATGCACAACA
1841 GTCCAGGAAAATGGGCGGTGGACACTTGAGGCTGAGGATGGGAGTTGACATGAGCAGGGAGAGGGAGGTGCGCGCTGCTT
1921 ATCTGTGATTGTTGCTCACCTGAGTGTGGCTGATTGTGTACATCCAGCAGTTACAATTTTTAAAAATTATACTTTTACAT
2001 TTATTTTATATTTTTCTCACCCCCAGTAATTTCCTTCCAAAGAAGTTCACATGTAATAAGTAGAAATTCTGTATAGGAAA
2081 AAAGCATTAAAAATACTATTATAACTGCTTCATTTGCTGGGAACCATTAAAAGTAATATAAATTAGCTTTTTCCAGAAGG
2161 ATCCTTTTGTAGCAGTGTTTATGAATGTAACCCCCAGCAAAATATGGCTATATATTAGGGGAGCCAGTTTGGAGCAGAGG
2241 CCTGAAGGTCCCTGCTATGCAGCCGTGGCCACAGCTCGCAGCCCAAGCACTGTGGAGCATCCACACCTTTGATGGCAATG
2321 CAGATTGGTAGCAGGTTCCATAGGCGTACAAAACAGTATTAAAGCTCAGTGTTTTGCATATTGTTAGCATTTACAAATAT
2401 TTTTGCTTTAGTATGAGGAAAGTAAGGATGGGCAAAGAAGCGATCAAAATAGCTATTGCTACAACATTTTCGAAAACAAA
2481 GTTGGGGCTGTATTTCTTTAAAAAGATAAGCCTCTAAAAATGCTTGGCAAAAAAAATATAGTGTTAAAATAGGCCAGTGA
2561 TATTAATGAGAAAATGAAAGTATGTATCAGGAATAAAGTGATATTGCATAGGAGTATTGTATTTTTATGAATTTTATGCC
2641 AGTTGTTTACATGTACTATATATGTTAAATTAAAAAAAATCATGAGTAATGAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaCGU--CACCU----GGU------CCUACCGUUc 5'
            |||  |||||    |||       |||||||| 
Target 5' aaGCACTGTGGAGCATCCACACCTTTGATGGCAAt 3'
 2285 - 2319 155.00 -17.40
2 
miRNA  3' uacGUCACCUG--GUC--CUACCGUUc 5'
             |||| |||  :||   ||||:|| 
Target 5' gaaCAGTAGACTGTAGTACATGGTAAt 3'
 959 - 985 144.00 -13.00
3 
miRNA  3' uaCGU-CACCU---GGUCCUA-CCGUUc 5'
            |:| | |||   : ||||| ||||| 
Target 5' taGTATGAGGAAAGTAAGGATGGGCAAa 3'
 2409 - 2436 129.00 -15.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN2376243 23 COSMIC
COSN31506627 46 COSMIC
COSN30191022 50 COSMIC
COSN31521449 56 COSMIC
COSN31484918 75 COSMIC
COSN30168012 108 COSMIC
COSN30112463 171 COSMIC
COSN30120625 356 COSMIC
COSN21199629 444 COSMIC
COSN30317949 657 COSMIC
COSN15662816 1114 COSMIC
COSN22591194 1137 COSMIC
COSN2220761 1155 COSMIC
COSN15668205 1191 COSMIC
COSN31848761 1339 COSMIC
COSN23728452 1643 COSMIC
COSN31962765 1645 COSMIC
COSN1348865 1848 COSMIC
COSN22689356 2312 COSMIC
COSN26339189 2382 COSMIC
COSN5100303 2562 COSMIC
COSN5100302 2634 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs749686265 5 dbSNP
rs1250117100 6 dbSNP
rs780550887 9 dbSNP
rs1326728943 11 dbSNP
rs1259939165 12 dbSNP
rs1378152775 18 dbSNP
rs1483046647 19 dbSNP
rs1421098606 22 dbSNP
rs371914783 23 dbSNP
rs750907481 27 dbSNP
rs750348096 30 dbSNP
rs1451248490 38 dbSNP
rs777193250 39 dbSNP
rs1371619749 41 dbSNP
rs781051508 51 dbSNP
rs1306774786 57 dbSNP
rs1351826865 59 dbSNP
rs1242084628 65 dbSNP
rs534300547 66 dbSNP
rs1323147410 67 dbSNP
rs966526646 70 dbSNP
rs1261403729 71 dbSNP
rs1217465628 76 dbSNP
rs1020643326 81 dbSNP
rs1010558259 84 dbSNP
rs1337833289 90 dbSNP
rs1178445677 93 dbSNP
rs1300547492 100 dbSNP
rs1236678815 102 dbSNP
rs754871744 119 dbSNP
rs1390399463 120 dbSNP
rs1367523727 124 dbSNP
rs1455981481 131 dbSNP
rs1292154112 132 dbSNP
rs1395173856 134 dbSNP
rs1459831567 138 dbSNP
rs1369258928 169 dbSNP
rs1033245246 178 dbSNP
rs1329079430 179 dbSNP
rs1170297031 189 dbSNP
rs1378767776 195 dbSNP
rs1393367568 197 dbSNP
rs1308061779 199 dbSNP
rs1340084350 200 dbSNP
rs1007105746 216 dbSNP
rs1336138619 217 dbSNP
rs1425912602 219 dbSNP
rs890025224 222 dbSNP
rs1051308014 228 dbSNP
rs1481861904 229 dbSNP
rs1178126190 233 dbSNP
rs934132785 239 dbSNP
rs1421653294 242 dbSNP
rs1189478949 244 dbSNP
rs897272332 248 dbSNP
rs1037088398 249 dbSNP
rs1168371595 257 dbSNP
rs1447526348 257 dbSNP
rs574954973 261 dbSNP
rs909844434 266 dbSNP
rs1207835209 269 dbSNP
rs1401816848 275 dbSNP
rs1186717 276 dbSNP
rs937977278 279 dbSNP
rs529118174 280 dbSNP
rs1218085876 281 dbSNP
rs1276923300 284 dbSNP
rs1309754224 297 dbSNP
rs1197663579 298 dbSNP
rs927869005 316 dbSNP
rs1482086081 327 dbSNP
rs981991877 328 dbSNP
rs1279560310 330 dbSNP
rs538073063 342 dbSNP
rs1190863389 347 dbSNP
rs1421630579 361 dbSNP
rs1429017818 362 dbSNP
rs1175131357 370 dbSNP
rs1219716446 371 dbSNP
rs1020675741 372 dbSNP
rs1299893427 378 dbSNP
rs1376275607 386 dbSNP
rs1388866387 388 dbSNP
rs1399526768 390 dbSNP
rs1287155545 396 dbSNP
rs989168720 398 dbSNP
rs1215615070 403 dbSNP
rs1301037850 403 dbSNP
rs1310744574 406 dbSNP
rs141365062 407 dbSNP
rs1280673089 422 dbSNP
rs1351414054 427 dbSNP
rs1487745976 428 dbSNP
rs1017256277 434 dbSNP
rs1007632403 444 dbSNP
rs1464283125 445 dbSNP
rs1190484569 449 dbSNP
rs1265177133 450 dbSNP
rs1402477085 451 dbSNP
rs1455465329 458 dbSNP
rs1395960475 461 dbSNP
rs756661932 461 dbSNP
rs73693345 468 dbSNP
rs1477777024 479 dbSNP
rs1376983716 481 dbSNP
rs1196725956 482 dbSNP
rs1434652697 483 dbSNP
rs1369416408 497 dbSNP
rs1186716 500 dbSNP
rs1304589498 502 dbSNP
rs998377488 505 dbSNP
rs1221669523 522 dbSNP
rs1285751448 531 dbSNP
rs1177563342 532 dbSNP
rs1456175441 537 dbSNP
rs897303486 540 dbSNP
rs1259667530 543 dbSNP
rs755895325 544 dbSNP
rs1439329301 551 dbSNP
rs1343735538 557 dbSNP
rs1254737477 561 dbSNP
rs566138977 584 dbSNP
rs941391598 588 dbSNP
rs888525760 596 dbSNP
rs1392971234 602 dbSNP
rs1372119344 605 dbSNP
rs1463438476 616 dbSNP
rs1327021375 621 dbSNP
rs1309004656 623 dbSNP
rs1440462429 624 dbSNP
rs1444749793 630 dbSNP
rs546154188 631 dbSNP
rs1332363045 635 dbSNP
rs1413952216 638 dbSNP
rs1373578163 640 dbSNP
rs780892182 656 dbSNP
rs1170694585 657 dbSNP
rs796293464 663 dbSNP
rs1395389160 665 dbSNP
rs1055171068 678 dbSNP
rs1437657636 679 dbSNP
rs1491194098 679 dbSNP
rs937992628 680 dbSNP
rs1182129705 681 dbSNP
rs1441295489 691 dbSNP
rs1253489201 692 dbSNP
rs1202641623 698 dbSNP
rs927933023 698 dbSNP
rs1166373056 705 dbSNP
rs529761092 706 dbSNP
rs1349237115 710 dbSNP
rs1286010142 712 dbSNP
rs1408619676 716 dbSNP
rs368482525 717 dbSNP
rs1238409357 730 dbSNP
rs1446764721 733 dbSNP
rs1290915476 736 dbSNP
rs945232087 750 dbSNP
rs1233362073 751 dbSNP
rs1277557112 755 dbSNP
rs1337347991 778 dbSNP
rs750222767 778 dbSNP
rs989199790 779 dbSNP
rs1280324316 783 dbSNP
rs1210369371 784 dbSNP
rs957820782 792 dbSNP
rs910273311 798 dbSNP
rs1188719882 801 dbSNP
rs375408268 802 dbSNP
rs985840675 808 dbSNP
rs1170027100 815 dbSNP
rs954496073 828 dbSNP
rs1413556852 842 dbSNP
rs1029931542 844 dbSNP
rs1336256770 846 dbSNP
rs1414925373 847 dbSNP
rs1396747885 851 dbSNP
rs1186715 854 dbSNP
rs1270567146 856 dbSNP
rs961545361 861 dbSNP
rs1015805344 872 dbSNP
rs1005720585 878 dbSNP
rs1350284846 880 dbSNP
rs888556957 881 dbSNP
rs1381974740 884 dbSNP
rs1055605929 888 dbSNP
rs1445784249 894 dbSNP
rs1195868777 901 dbSNP
rs1243192840 903 dbSNP
rs1454156028 907 dbSNP
rs1472268396 914 dbSNP
rs191068276 918 dbSNP
rs1189012337 937 dbSNP
rs186119157 940 dbSNP
rs1263069364 946 dbSNP
rs1382071386 953 dbSNP
rs1383856839 957 dbSNP
rs1215130792 959 dbSNP
rs1489450245 969 dbSNP
rs1330424690 970 dbSNP
rs751280802 971 dbSNP
rs1305305784 974 dbSNP
rs1350347583 976 dbSNP
rs1235219110 977 dbSNP
rs1046315601 979 dbSNP
rs1175353830 981 dbSNP
rs563996100 989 dbSNP
rs545419793 998 dbSNP
rs1354504586 1008 dbSNP
rs1468407388 1011 dbSNP
rs1192191876 1015 dbSNP
rs1255232669 1018 dbSNP
rs1454457576 1028 dbSNP
rs1184064058 1030 dbSNP
rs1361704804 1035 dbSNP
rs893781781 1040 dbSNP
rs936493223 1040 dbSNP
rs1233953851 1041 dbSNP
rs750856463 1045 dbSNP
rs1339993651 1049 dbSNP
rs1371370422 1065 dbSNP
rs910314428 1068 dbSNP
rs1306628449 1080 dbSNP
rs763527846 1088 dbSNP
rs1334185441 1093 dbSNP
rs562935923 1098 dbSNP
rs1334794748 1103 dbSNP
rs1212303532 1113 dbSNP
rs1275448510 1121 dbSNP
rs1469244058 1122 dbSNP
rs1195566331 1125 dbSNP
rs151228391 1127 dbSNP
rs1318732297 1136 dbSNP
rs1404618004 1138 dbSNP
rs1416443551 1139 dbSNP
rs1411161995 1143 dbSNP
rs1164681941 1145 dbSNP
rs1475230227 1148 dbSNP
rs922895109 1154 dbSNP
rs1395104803 1157 dbSNP
rs1422325298 1158 dbSNP
rs1296210174 1161 dbSNP
rs1394649062 1170 dbSNP
rs1393314839 1171 dbSNP
rs1192065427 1176 dbSNP
rs565564908 1177 dbSNP
rs546481662 1180 dbSNP
rs1295716954 1183 dbSNP
rs1227190521 1185 dbSNP
rs1249927425 1189 dbSNP
rs971715405 1198 dbSNP
rs961662413 1200 dbSNP
rs1256358744 1205 dbSNP
rs1015836555 1210 dbSNP
rs73693344 1212 dbSNP
rs1221281329 1214 dbSNP
rs1450296274 1230 dbSNP
rs1427811546 1240 dbSNP
rs952828671 1247 dbSNP
rs1033788583 1250 dbSNP
rs1002662259 1262 dbSNP
rs560494941 1262 dbSNP
rs906543815 1266 dbSNP
rs1413053775 1286 dbSNP
rs1046868965 1299 dbSNP
rs1380556978 1304 dbSNP
rs1382099061 1305 dbSNP
rs1009503139 1309 dbSNP
rs1309697261 1320 dbSNP
rs892410030 1341 dbSNP
rs540606802 1344 dbSNP
rs1345258251 1351 dbSNP
rs574865029 1360 dbSNP
rs936525843 1361 dbSNP
rs555080819 1363 dbSNP
rs910336849 1365 dbSNP
rs1050190664 1368 dbSNP
rs933099297 1371 dbSNP
rs1263759054 1372 dbSNP
rs1428962342 1374 dbSNP
rs1363984185 1376 dbSNP
rs1270756971 1379 dbSNP
rs1175612844 1384 dbSNP
rs923043407 1385 dbSNP
rs1453135466 1386 dbSNP
rs1287687840 1389 dbSNP
rs1364668944 1393 dbSNP
rs1436326850 1400 dbSNP
rs971747966 1420 dbSNP
rs940326590 1421 dbSNP
rs1235971576 1423 dbSNP
rs1327448664 1425 dbSNP
rs908808675 1428 dbSNP
rs1213020862 1429 dbSNP
rs1262474242 1436 dbSNP
rs1398842261 1438 dbSNP
rs1486130145 1446 dbSNP
rs1167915245 1456 dbSNP
rs1192796154 1459 dbSNP
rs1250844388 1460 dbSNP
rs984350164 1484 dbSNP
rs1420825235 1485 dbSNP
rs1191166324 1495 dbSNP
rs952914775 1496 dbSNP
rs537944998 1497 dbSNP
rs1400240887 1499 dbSNP
rs1156971249 1502 dbSNP
rs1347499305 1505 dbSNP
rs1458185885 1509 dbSNP
rs1034232113 1512 dbSNP
rs1392659145 1518 dbSNP
rs1194442778 1525 dbSNP
rs1457487249 1532 dbSNP
rs980958630 1533 dbSNP
rs1308454720 1540 dbSNP
rs971241045 1542 dbSNP
rs1200589832 1543 dbSNP
rs182844321 1545 dbSNP
rs558426175 1546 dbSNP
rs892441492 1548 dbSNP
rs1032221297 1550 dbSNP
rs1365160990 1554 dbSNP
rs538561525 1562 dbSNP
rs1410183996 1568 dbSNP
rs566400574 1572 dbSNP
rs1473209568 1576 dbSNP
rs762346508 1582 dbSNP
rs889030141 1597 dbSNP
rs1463390714 1601 dbSNP
rs1441457038 1602 dbSNP
rs1050726183 1604 dbSNP
rs933150359 1610 dbSNP
rs116517688 1613 dbSNP
rs1291412883 1614 dbSNP
rs1336812912 1618 dbSNP
rs535875039 1619 dbSNP
rs866229213 1620 dbSNP
rs1437482159 1621 dbSNP
rs1463046898 1621 dbSNP
rs1234816001 1625 dbSNP
rs940357403 1628 dbSNP
rs763696061 1630 dbSNP
rs192057633 1634 dbSNP
rs984382682 1635 dbSNP
rs1175915528 1640 dbSNP
rs931592633 1642 dbSNP
rs1397202393 1644 dbSNP
rs550694682 1645 dbSNP
rs926895080 1646 dbSNP
rs981374923 1657 dbSNP
rs1413677521 1677 dbSNP
rs1236556685 1682 dbSNP
rs1310499380 1683 dbSNP
rs970888939 1701 dbSNP
rs530475180 1702 dbSNP
rs764178182 1711 dbSNP
rs1480975377 1718 dbSNP
rs1236996785 1720 dbSNP
rs569445163 1724 dbSNP
rs1210300408 1735 dbSNP
rs1255432780 1739 dbSNP
rs1444637218 1742 dbSNP
rs552178462 1746 dbSNP
rs1242028301 1748 dbSNP
rs1032337871 1754 dbSNP
rs1000870218 1760 dbSNP
rs889055229 1765 dbSNP
rs1390437187 1768 dbSNP
rs1028897924 1792 dbSNP
rs3735412 1796 dbSNP
rs1306581261 1808 dbSNP
rs770706126 1821 dbSNP
rs1392795769 1826 dbSNP
rs1324600091 1827 dbSNP
rs532881000 1834 dbSNP
rs1298016823 1836 dbSNP
rs1366231007 1838 dbSNP
rs367845334 1839 dbSNP
rs1036118099 1856 dbSNP
rs1377782320 1857 dbSNP
rs1201082075 1861 dbSNP
rs1284227785 1863 dbSNP
rs1314075319 1864 dbSNP
rs1419449008 1878 dbSNP
rs1190933286 1884 dbSNP
rs1248969707 1885 dbSNP
rs113992641 1886 dbSNP
rs1191434837 1890 dbSNP
rs1378992064 1890 dbSNP
rs1161487615 1896 dbSNP
rs940389546 1897 dbSNP
rs1157454447 1898 dbSNP
rs1419907606 1904 dbSNP
rs1402327932 1905 dbSNP
rs1320997013 1909 dbSNP
rs776015751 1910 dbSNP
rs773128799 1911 dbSNP
rs187334779 1912 dbSNP
rs1180182192 1913 dbSNP
rs926879166 1914 dbSNP
rs1278982957 1919 dbSNP
rs1349176319 1927 dbSNP
rs1211056086 1928 dbSNP
rs137969541 1929 dbSNP
rs1468365374 1931 dbSNP
rs1212186797 1951 dbSNP
rs181596454 1954 dbSNP
rs1451783342 1956 dbSNP
rs1487811660 1971 dbSNP
rs561124412 1974 dbSNP
rs1180499508 1981 dbSNP
rs1283640897 1987 dbSNP
rs1473283019 1987 dbSNP
rs770235703 1989 dbSNP
rs1240659194 1992 dbSNP
rs1159889974 1993 dbSNP
rs1417043855 1995 dbSNP
rs1317137399 2000 dbSNP
rs1327622946 2002 dbSNP
rs1311638555 2008 dbSNP
rs918050659 2008 dbSNP
rs1387507057 2009 dbSNP
rs1328274068 2016 dbSNP
rs988260130 2018 dbSNP
rs956825981 2023 dbSNP
rs925352979 2024 dbSNP
rs1334732720 2036 dbSNP
rs748147037 2042 dbSNP
rs1267559914 2044 dbSNP
rs780802229 2045 dbSNP
rs1313977348 2046 dbSNP
rs1194812699 2048 dbSNP
rs1247960451 2051 dbSNP
rs1483777085 2057 dbSNP
rs1282251394 2058 dbSNP
rs1256755243 2059 dbSNP
rs746214084 2072 dbSNP
rs112547100 2073 dbSNP
rs1029344595 2074 dbSNP
rs997404754 2084 dbSNP
rs768313290 2089 dbSNP
rs1461292931 2098 dbSNP
rs1167619028 2101 dbSNP
rs1291001589 2108 dbSNP
rs1454688782 2109 dbSNP
rs965878046 2111 dbSNP
rs1413415590 2121 dbSNP
rs1315279305 2133 dbSNP
rs1322756528 2137 dbSNP
rs1227121858 2139 dbSNP
rs1014801791 2143 dbSNP
rs1476206838 2154 dbSNP
rs1343802077 2161 dbSNP
rs746593501 2163 dbSNP
rs777185470 2165 dbSNP
rs1004718044 2166 dbSNP
rs1188497309 2169 dbSNP
rs1278917197 2169 dbSNP
rs887553158 2172 dbSNP
rs575614730 2184 dbSNP
rs758135632 2195 dbSNP
rs1259656210 2198 dbSNP
rs905487152 2201 dbSNP
rs1045731979 2209 dbSNP
rs1206658771 2210 dbSNP
rs1486099115 2216 dbSNP
rs1374859173 2218 dbSNP
rs558738921 2220 dbSNP
rs185471047 2228 dbSNP
rs557054123 2229 dbSNP
rs779382289 2230 dbSNP
rs1293382678 2234 dbSNP
rs1295791008 2240 dbSNP
rs1366933824 2244 dbSNP
rs1052576081 2247 dbSNP
rs34212206 2253 dbSNP
rs935488950 2264 dbSNP
rs1345193156 2269 dbSNP
rs10928 2274 dbSNP
rs552888011 2277 dbSNP
rs536136070 2278 dbSNP
rs979518183 2292 dbSNP
rs757710694 2312 dbSNP
rs1203190819 2315 dbSNP
rs953507395 2325 dbSNP
rs1383098636 2327 dbSNP
rs921923194 2328 dbSNP
rs1291956626 2330 dbSNP
rs112321053 2340 dbSNP
rs1014845054 2345 dbSNP
rs1004729305 2346 dbSNP
rs1464189240 2350 dbSNP
rs1371244201 2358 dbSNP
rs951822646 2367 dbSNP
rs1044428 2371 dbSNP
rs1318966420 2374 dbSNP
rs1195287123 2389 dbSNP
rs1436257495 2390 dbSNP
rs1027837486 2393 dbSNP
rs1302300778 2396 dbSNP
rs1428852810 2411 dbSNP
rs1220483885 2421 dbSNP
rs1001264099 2422 dbSNP
rs1316287428 2427 dbSNP
rs1236716211 2428 dbSNP
rs1269940381 2432 dbSNP
rs1044455 2439 dbSNP
rs7511 2441 dbSNP
rs115222814 2442 dbSNP
rs1487597748 2442 dbSNP
rs752884406 2450 dbSNP
rs1013873738 2452 dbSNP
rs896777043 2453 dbSNP
rs1469535039 2455 dbSNP
rs767632918 2456 dbSNP
rs77896149 2471 dbSNP
rs1458134474 2472 dbSNP
rs1052603960 2477 dbSNP
rs1347781365 2487 dbSNP
rs1273496627 2489 dbSNP
rs1293615038 2490 dbSNP
rs1292535420 2492 dbSNP
rs1197437757 2494 dbSNP
rs1407442540 2500 dbSNP
rs1290178478 2503 dbSNP
rs1329728673 2506 dbSNP
rs1232475375 2516 dbSNP
rs1287393750 2518 dbSNP
rs1436770706 2520 dbSNP
rs1320146711 2524 dbSNP
rs935503766 2526 dbSNP
rs903996630 2529 dbSNP
rs759844836 2535 dbSNP
rs932112306 2536 dbSNP
rs921990767 2537 dbSNP
rs1473177437 2538 dbSNP
rs1164676529 2539 dbSNP
rs1253560175 2542 dbSNP
rs551483174 2543 dbSNP
rs976145803 2549 dbSNP
rs1407436643 2553 dbSNP
rs1165117061 2554 dbSNP
rs532787552 2561 dbSNP
rs1353541058 2564 dbSNP
rs775483560 2575 dbSNP
rs567060911 2579 dbSNP
rs907798082 2583 dbSNP
rs374445121 2584 dbSNP
rs879287459 2586 dbSNP
rs1381148274 2589 dbSNP
rs1156312853 2590 dbSNP
rs1228650240 2595 dbSNP
rs145350684 2604 dbSNP
rs1341676082 2608 dbSNP
rs1203138813 2614 dbSNP
rs1276792940 2616 dbSNP
rs1483672589 2619 dbSNP
rs1187959660 2621 dbSNP
rs1027519668 2622 dbSNP
rs980325995 2629 dbSNP
rs1182761251 2631 dbSNP
rs530285035 2636 dbSNP
rs761802153 2639 dbSNP
rs1169939668 2640 dbSNP
rs1370706389 2641 dbSNP
rs561348732 2645 dbSNP
rs1433547227 2652 dbSNP
rs776714927 2660 dbSNP
rs1360794029 2670 dbSNP
rs1448524121 2672 dbSNP
rs1269327960 2675 dbSNP
rs1444614971 2680 dbSNP
rs1226376815 2681 dbSNP
rs1300094153 2686 dbSNP
rs1127886 2687 dbSNP
rs1169526852 2691 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796040. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_015283 | 3UTR | UUGGGGCUGUAUUUCUUUAAAAAGAUAAGCCUCUAAAAAUGCUUGGCAAAAAAAAUAUAGUGUUAAAAUAGGCCAGUGAUAUUAAUGAGAAAAUGAAAGUAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000310974.4 | 3UTR | UUGGCAAAAAAAAUAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM796040
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000310974.4 | 3UTR | UUGGCAAAAAAAAUAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
104 hsa-miR-4776-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT107576 VLDLR very low density lipoprotein receptor 2 2
MIRT183601 SNRPE small nuclear ribonucleoprotein polypeptide E 2 4
MIRT208901 PDCD10 programmed cell death 10 2 2
MIRT441496 IFFO2 intermediate filament family orphan 2 2 2
MIRT441590 PSTK phosphoseryl-tRNA kinase 2 2
MIRT441865 RNASEL ribonuclease L 2 2
MIRT442155 DPY19L1 dpy-19 like C-mannosyltransferase 1 2 2
MIRT442235 DDX19A DEAD-box helicase 19A 2 2
MIRT442519 MOB3B MOB kinase activator 3B 2 2
MIRT443347 STX7 syntaxin 7 2 2
MIRT443598 ZNF91 zinc finger protein 91 2 2
MIRT443725 USP14 ubiquitin specific peptidase 14 2 2
MIRT453650 RAB6C RAB6C, member RAS oncogene family 2 2
MIRT464155 VMP1 vacuole membrane protein 1 2 11
MIRT472507 NACC1 nucleus accumbens associated 1 2 4
MIRT476018 GTF2A1 general transcription factor IIA subunit 1 2 2
MIRT477716 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2 2
MIRT478545 CTNND1 catenin delta 1 2 2
MIRT481629 ARF1 ADP ribosylation factor 1 2 2
MIRT486451 MDM2 MDM2 proto-oncogene 2 2
MIRT494856 ZNF99 zinc finger protein 99 2 4
MIRT495096 FXR1 FMR1 autosomal homolog 1 2 2
MIRT495766 ZNF546 zinc finger protein 546 2 2
MIRT496650 PITPNM3 PITPNM family member 3 2 2
MIRT496920 CLMN calmin 2 2
MIRT496997 SNAP25 synaptosome associated protein 25 2 2
MIRT497056 C6orf223 chromosome 6 open reading frame 223 2 2
MIRT498391 KIF6 kinesin family member 6 2 2
MIRT499057 CTBP1 C-terminal binding protein 1 2 4
MIRT499093 DENND4C DENN domain containing 4C 2 8
MIRT499860 SVOP SV2 related protein 2 12
MIRT501968 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT504910 CD38 CD38 molecule 2 4
MIRT506781 KLHL15 kelch like family member 15 2 6
MIRT509549 ACTG1 actin gamma 1 2 4
MIRT510814 SBNO1 strawberry notch homolog 1 2 4
MIRT515490 NTRK3 neurotrophic receptor tyrosine kinase 3 2 4
MIRT517752 ZNF366 zinc finger protein 366 2 4
MIRT518553 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT518633 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT518721 ABCG8 ATP binding cassette subfamily G member 8 2 2
MIRT524469 CHRM3 cholinergic receptor muscarinic 3 2 4
MIRT525213 ZNF253 zinc finger protein 253 2 2
MIRT527556 ADCY7 adenylate cyclase 7 2 2
MIRT532691 TCN2 transcobalamin 2 2 4
MIRT533124 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 2
MIRT534080 SPRY4 sprouty RTK signaling antagonist 4 2 2
MIRT534437 SDR16C5 short chain dehydrogenase/reductase family 16C member 5 2 2
MIRT534997 PRPF40A pre-mRNA processing factor 40 homolog A 2 4
MIRT537160 GGCX gamma-glutamyl carboxylase 2 2
MIRT539359 AFF4 AF4/FMR2 family member 4 2 2
MIRT547019 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT550122 ZNF138 zinc finger protein 138 2 2
MIRT558471 DBN1 drebrin 1 2 2
MIRT563055 ZNF28 zinc finger protein 28 2 2
MIRT563550 SCP2 sterol carrier protein 2 2 2
MIRT566860 LRRC58 leucine rich repeat containing 58 2 2
MIRT567239 HSPA13 heat shock protein family A (Hsp70) member 13 2 2
MIRT572846 BRPF3 bromodomain and PHD finger containing 3 2 2
MIRT573355 PDE3A phosphodiesterase 3A 2 2
MIRT573761 PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 2 2
MIRT574911 Vmp1 vacuole membrane protein 1 2 7
MIRT610172 SEC14L4 SEC14 like lipid binding 4 2 2
MIRT611271 RBMXL1 RNA binding motif protein, X-linked like 1 2 2
MIRT612325 TRPS1 transcriptional repressor GATA binding 1 2 2
MIRT612720 NOL4 nucleolar protein 4 2 2
MIRT613093 ETS1 ETS proto-oncogene 1, transcription factor 2 2
MIRT613759 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT614788 RRAGC Ras related GTP binding C 2 2
MIRT614926 MARCH3 membrane associated ring-CH-type finger 3 2 2
MIRT616777 CD44 CD44 molecule (Indian blood group) 2 2
MIRT616892 DUSP1 dual specificity phosphatase 1 2 2
MIRT618446 SERPINA3 serpin family A member 3 2 2
MIRT619155 PPDPF pancreatic progenitor cell differentiation and proliferation factor 2 2
MIRT619271 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT620899 MUT methylmalonyl-CoA mutase 2 2
MIRT621151 MICALCL MICAL C-terminal like 2 2
MIRT622138 SOX4 SRY-box 4 2 2
MIRT622925 PAK7 p21 (RAC1) activated kinase 5 2 2
MIRT623595 IPO9 importin 9 2 2
MIRT623916 FNBP1L formin binding protein 1 like 2 2
MIRT624072 EBF1 early B-cell factor 1 2 2
MIRT630961 NGDN neuroguidin 2 2
MIRT636738 ADD3 adducin 3 2 2
MIRT639788 MVK mevalonate kinase 2 2
MIRT641106 ZNF274 zinc finger protein 274 2 2
MIRT641573 RFX1 regulatory factor X1 2 2
MIRT643089 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT646457 PRDM10 PR/SET domain 10 2 2
MIRT653068 ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2 2
MIRT657672 GPR26 G protein-coupled receptor 26 2 2
MIRT660287 BICC1 BicC family RNA binding protein 1 2 2
MIRT660354 BAG4 BCL2 associated athanogene 4 2 2
MIRT665823 TIMM8B translocase of inner mitochondrial membrane 8 homolog B 2 2
MIRT678564 ZNF786 zinc finger protein 786 2 2
MIRT691520 ZNF208 zinc finger protein 208 2 2
MIRT695586 TMEM199 transmembrane protein 199 2 2
MIRT698033 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT701012 PCGF5 polycomb group ring finger 5 2 2
MIRT701353 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT704846 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT707112 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT718656 HNF4A hepatocyte nuclear factor 4 alpha 2 2
MIRT720561 C1RL complement C1r subcomponent like 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4776-3p Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer cell line (Bads-200, Bats-72, BCap37)
hsa-miR-4776-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-miR-4776-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-miR-4776-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-4776-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-4776-3p Neoadjuvant chemotherapy resistant tissue (breast cancer)

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