miRTarBase - #MIRT442418


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pre-miRNA Information
pre-miRNA hsa-mir-4729   
Genomic Coordinates chr17: 59366083 - 59366154
Description Homo sapiens miR-4729 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4729
Sequence 10| UCAUUUAUCUGUUGGGAAGCUA |31
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN28205519 5 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1167550125 15 dbSNP
rs1022075979 18 dbSNP
rs967769645 19 dbSNP
Putative Targets

Gene Information
Gene Symbol LBR   
Synonyms DHCR14B, LMN2R, PHA, TDRD18
Description lamin B receptor
Transcript NM_002296   
Other Transcripts NM_194442   
Expression
Putative miRNA Targets on LBR
3'UTR of LBR
(miRNA target sites are highlighted)		 
>LBR|NM_002296|3'UTR
   1 TGCTCTTCTGGCTTTTCTACAAAATACTCCTGCAATTCCAGCTGCCATTTGCAAAAACAAGGAAAAAAATCCGAAACTTT
  81 CTTTTGTTGCACTGACAGGGTCTGTACTTTTTTTTTTCTTTTTGAGTCAGGACTATGGAGCCGAGTAGTTGATCTTTTAA
 161 TATAGCCGTGTTTACTTGTATTAACTTACAGTTAACATAGGAAAAATACAAGTAAGGATGTGAGAATTTGCATTTTAATG
 241 GGAAATTTTCAACCCTTAATCTGAAAACAGAAGACAGTCTTAATATAAATGTACTGTGAAGAATGCTATTGATGTTTATG
 321 GTTTCTGATTACTTTTCAAATTTTGATGTTTTTTTGCCAGTTGGCTTTTCTTAAATGAAAACACTGTTCCATTTAAAGTA
 401 CATTTATGTTTTATTCAGTAAGAGAATAGAATTTTCATTTGTTTTTCTTTAAATCCTTTACTAATTATATAATTTGAAAG
 481 CAAAAAGAAGGGCCTATATTAAATGCTGAAAGTGAAAAGTGATGACATTATTAGCAGACACTGCTTAAAGGAGACCATTT
 561 GTAGCAGTTGGCTTAACCTCAACTTCTAAAACTACATTGAAAATGTAAATACATAGCTTAGTTTTTTGTAATATATGGTG
 641 ACTTCAGATTTTTTTGTACAGTATTTTGAATGTGAGATGATTGTCAGGACTAACTGTCTTTTTAACAAAACATTTTCAGT
 721 ATTTTAAATAAAATTTTGTAAAGTAATGTGAATTAAAAATTTTGGAACAATTAGAATTCATTCACTATTGTATAGAAGAT
 801 GCTGTTAAAACATAGGAAGGGTATTTTTCTTGATCCAAAGTTTGTGAATTTGGCTTTGCTACCTCAATTGCAGGTGTTTG
 881 TTTGCCTTTATAAACTGTTGCAAATAGAAAAAAAATAGAATAAGTATATATTTTTGGAGTAACATCAATATTTAAACATT
 961 TTTACACAGATCGGTGTTTGAAAATTTGCCATTTCAGGCTAATATTTTTATATATTTTTGACTTTTTAAAAGTTCATCAG
1041 TGTTTTTGCTACTGTTAAGCTTATGCAGTTTATACTGTATTTTTTATGTATCCTTTATATTTACCAAACCTGACTCCCTG
1121 TAAAGGAGTGCTGTCTTAAAAACAACTGAAGGGGTTAAAGTCGTTTCTTTTAGTTTAATAGATGTGCATAAGGTAGCTTT
1201 AGCAATTAAATTCTAGTGAAGTTGATATAGTCTCATTTTTAATTGTCCTGTAATGGAACAGTAGCAAATTCACTAAACTT
1281 TTGTGTTCAGAGTTAAATTGTTCTCAGTACTTTCAATGTAGGGGAATGTAATAAACATAGTGTGTATGTTTGGGTTTTAA
1361 TTACACATTTTATATATGAGCCATTTAGATATGCAGTGTTAATTCTATACTGCATTTGAAGTGTATGTAACTTAGCTTAT
1441 GTTAATGCAGTCATGAAGTTGGTTTGCTCCAGCATCCGGTAGTCTTTAAACATTCTTTTAGTGAAATTGTCATTGTTTTA
1521 TCAGTGCTAATGTGTGCAAGCAGTTTTTTTATTTTGCTTTTCTCCTGGCATCAGAAAGTGGTGGCGTTTTCTGTACTGGA
1601 TTGCACCAAGGAAGCTTTTGGGGAGGAAGGAAGGACATTAAATTCTTTCCCTGGTAATGAAAAGAGCCCTTTATCAATAC
1681 AGTGCTGCAATTTCTGGATATCAGCTACACTTTGTTTTTAAGTTTGTTTTTGACATGTTTATTTGGCAAATTTTATAATG
1761 AAGTTTTAAGTTGAAAATAAAATGTAGCAACATTTTGATCAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aucgaAGGGUUGUCUAUUUACu 5'
               ||::||:  ||||||| 
Target 5' gacagTCTTAAT--ATAAATGt 3'
 273 - 292 153.00 -7.50
2 
miRNA  3' auCGAAGGGUUGUC----UAUUUACu 5'
            |:|||::  :||    |||:||| 
Target 5' tcGTTTCTT-TTAGTTTAATAGATGt 3'
 1161 - 1185 133.00 -8.60
3 
miRNA  3' auCGAAGGGUUGUCUAUUUACu 5'
            ||||::|      |||||| 
Target 5' tgGCTTTTCT-----TAAATGa 3'
 362 - 378 122.00 -10.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
875096 27 ClinVar
875095 33 ClinVar
295928 255 ClinVar
295927 330 ClinVar
875094 362 ClinVar
295926 624 ClinVar
295925 656 ClinVar
295924 686 ClinVar
295923 769 ClinVar
295922 1049 ClinVar
295921 1128 ClinVar
295920 1200 ClinVar
874168 1201 ClinVar
295919 1305 ClinVar
295918 1361 ClinVar
876960 1498 ClinVar
295917 1532 ClinVar
876959 1586 ClinVar
876958 1595 ClinVar
876957 1769 ClinVar
876956 1800 ClinVar
COSN30168638 30 COSMIC
COSN20073762 51 COSMIC
COSN28871570 63 COSMIC
COSN30103223 67 COSMIC
COSN30505713 69 COSMIC
COSN30488904 72 COSMIC
COSN31603624 73 COSMIC
COSN30503753 80 COSMIC
COSN30751961 99 COSMIC
COSN30144096 105 COSMIC
COSN27580419 107 COSMIC
COSN6025227 135 COSMIC
COSN30178208 140 COSMIC
COSN30161930 340 COSMIC
COSN31550313 621 COSMIC
COSN5166649 639 COSMIC
COSN26548539 694 COSMIC
COSN31516870 807 COSMIC
COSN31594618 813 COSMIC
COSN26895344 1673 COSMIC
rs16844841 330 GWAS
rs7406 1532 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs985191237 2 dbSNP
rs1206128460 5 dbSNP
rs1307697586 8 dbSNP
rs201103298 16 dbSNP
rs1243133804 17 dbSNP
rs912676347 19 dbSNP
rs1381298291 20 dbSNP
rs774800175 22 dbSNP
rs769291635 23 dbSNP
rs1235886934 25 dbSNP
rs755166445 29 dbSNP
rs1396175975 30 dbSNP
rs761413449 32 dbSNP
rs749772181 33 dbSNP
rs373082891 35 dbSNP
rs756770029 39 dbSNP
rs746500003 41 dbSNP
rs1387024856 43 dbSNP
rs1184091558 45 dbSNP
rs370013700 51 dbSNP
rs1005826715 53 dbSNP
rs1020087463 63 dbSNP
rs190693979 65 dbSNP
rs1010052332 72 dbSNP
rs569229721 73 dbSNP
rs1034273033 76 dbSNP
rs557335269 81 dbSNP
rs1003593149 84 dbSNP
rs1434767004 84 dbSNP
rs1056844079 91 dbSNP
rs1298053628 92 dbSNP
rs1001574571 97 dbSNP
rs34846453 101 dbSNP
rs1336370687 103 dbSNP
rs906652015 104 dbSNP
rs535521971 107 dbSNP
rs1449593665 109 dbSNP
rs1195081539 115 dbSNP
rs1263707317 117 dbSNP
rs1421549600 118 dbSNP
rs377281070 118 dbSNP
rs893825258 118 dbSNP
rs945400630 118 dbSNP
rs567550669 122 dbSNP
rs1164275480 124 dbSNP
rs540694946 124 dbSNP
rs1465913860 125 dbSNP
rs1404155572 126 dbSNP
rs549037426 135 dbSNP
rs533725816 142 dbSNP
rs1398979763 143 dbSNP
rs1275934561 146 dbSNP
rs1356773894 151 dbSNP
rs918873432 154 dbSNP
rs1177811282 167 dbSNP
rs566349300 168 dbSNP
rs1422336481 169 dbSNP
rs944224450 176 dbSNP
rs912641708 188 dbSNP
rs113990759 195 dbSNP
rs933747456 197 dbSNP
rs1216105677 199 dbSNP
rs922373633 202 dbSNP
rs972407929 207 dbSNP
rs1188318167 208 dbSNP
rs985568984 209 dbSNP
rs1478747256 217 dbSNP
rs755810784 235 dbSNP
rs1263860938 240 dbSNP
rs932603176 242 dbSNP
rs925324699 243 dbSNP
rs1482184793 248 dbSNP
rs1254424397 252 dbSNP
rs979056811 252 dbSNP
rs11551874 255 dbSNP
rs1311384456 256 dbSNP
rs767353012 269 dbSNP
rs1277670567 274 dbSNP
rs1216919478 277 dbSNP
rs1033852204 279 dbSNP
rs1352625089 281 dbSNP
rs1004156634 291 dbSNP
rs1282273402 293 dbSNP
rs761467375 294 dbSNP
rs1296995731 305 dbSNP
rs751092768 311 dbSNP
rs1021432027 320 dbSNP
rs1009617892 321 dbSNP
rs16844841 330 dbSNP
rs762715244 332 dbSNP
rs774945026 339 dbSNP
rs1053715754 340 dbSNP
rs1035810101 344 dbSNP
rs1157222865 351 dbSNP
rs1379806463 356 dbSNP
rs1466204092 372 dbSNP
rs1304186013 375 dbSNP
rs1301947123 381 dbSNP
rs1470019532 391 dbSNP
rs1001311354 395 dbSNP
rs1000066037 401 dbSNP
rs771329334 430 dbSNP
rs1399151478 468 dbSNP
rs562482402 473 dbSNP
rs1376041725 487 dbSNP
rs1026639850 496 dbSNP
rs1373557714 506 dbSNP
rs995607324 519 dbSNP
rs922480181 527 dbSNP
rs1234171975 551 dbSNP
rs1255659260 561 dbSNP
rs572258776 582 dbSNP
rs1200620544 586 dbSNP
rs1037318610 597 dbSNP
rs1238934835 604 dbSNP
rs944152738 612 dbSNP
rs1269885688 613 dbSNP
rs565044223 617 dbSNP
rs939760688 619 dbSNP
rs1257742706 622 dbSNP
rs886046050 624 dbSNP
rs544921637 635 dbSNP
rs1320114856 640 dbSNP
rs80028106 656 dbSNP
rs983829757 659 dbSNP
rs1444444885 663 dbSNP
rs751678563 672 dbSNP
rs1295239609 673 dbSNP
rs886046049 686 dbSNP
rs1367988455 688 dbSNP
rs959605005 696 dbSNP
rs1339029116 707 dbSNP
rs773824068 712 dbSNP
rs1300782585 713 dbSNP
rs772541615 717 dbSNP
rs932763868 719 dbSNP
rs115463653 721 dbSNP
rs1315251584 736 dbSNP
rs1258763715 737 dbSNP
rs1317427644 738 dbSNP
rs1197251007 742 dbSNP
rs748270864 746 dbSNP
rs1267790105 747 dbSNP
rs1488974337 747 dbSNP
rs926898917 752 dbSNP
rs1265790988 753 dbSNP
rs1478579879 760 dbSNP
rs925387243 761 dbSNP
rs75904736 769 dbSNP
rs1463632932 774 dbSNP
rs1166746601 787 dbSNP
rs573448057 790 dbSNP
rs541475300 801 dbSNP
rs780484389 803 dbSNP
rs1021128770 812 dbSNP
rs945413768 813 dbSNP
rs913117453 814 dbSNP
rs1342187321 822 dbSNP
rs1009566864 834 dbSNP
rs1279107872 836 dbSNP
rs1339888225 843 dbSNP
rs1212888133 847 dbSNP
rs1396595381 853 dbSNP
rs988692952 854 dbSNP
rs1322843832 856 dbSNP
rs114577052 859 dbSNP
rs1264021236 862 dbSNP
rs1489488403 874 dbSNP
rs1035543740 878 dbSNP
rs867272119 880 dbSNP
rs1050085259 885 dbSNP
rs889692324 885 dbSNP
rs998127633 886 dbSNP
rs1036870151 916 dbSNP
rs900969652 916 dbSNP
rs757977362 924 dbSNP
rs1162655993 926 dbSNP
rs1177009851 928 dbSNP
rs1362169224 936 dbSNP
rs1420115118 936 dbSNP
rs939750836 942 dbSNP
rs115448388 944 dbSNP
rs969816905 948 dbSNP
rs937701097 949 dbSNP
rs1380038841 950 dbSNP
rs1228199122 951 dbSNP
rs1313593626 959 dbSNP
rs1356213286 960 dbSNP
rs1209373444 963 dbSNP
rs1285832033 966 dbSNP
rs557222889 972 dbSNP
rs146434391 973 dbSNP
rs896830282 974 dbSNP
rs1247153603 976 dbSNP
rs1015813561 984 dbSNP
rs1353451781 986 dbSNP
rs971013195 999 dbSNP
rs574777323 1005 dbSNP
rs1241909966 1012 dbSNP
rs914049774 1015 dbSNP
rs1335782600 1018 dbSNP
rs1322281436 1035 dbSNP
rs988309257 1039 dbSNP
rs886046048 1049 dbSNP
rs1336421642 1059 dbSNP
rs1384639311 1060 dbSNP
rs1447395917 1061 dbSNP
rs879054704 1068 dbSNP
rs1335245410 1072 dbSNP
rs1008501551 1077 dbSNP
rs368967565 1083 dbSNP
rs1032418037 1090 dbSNP
rs1308952339 1093 dbSNP
rs891258544 1104 dbSNP
rs1303705203 1105 dbSNP
rs1049907334 1109 dbSNP
rs953479594 1115 dbSNP
rs1201249728 1117 dbSNP
rs1030333738 1124 dbSNP
rs536222809 1128 dbSNP
rs903934502 1134 dbSNP
rs901122580 1151 dbSNP
rs573671761 1152 dbSNP
rs1478902359 1162 dbSNP
rs186699858 1163 dbSNP
rs945340302 1168 dbSNP
rs1426150365 1197 dbSNP
rs533835261 1200 dbSNP
rs566286795 1204 dbSNP
rs1174366916 1213 dbSNP
rs1417342169 1228 dbSNP
rs553767609 1228 dbSNP
rs1331284619 1234 dbSNP
rs888182258 1235 dbSNP
rs551149735 1250 dbSNP
rs1439062048 1251 dbSNP
rs539293039 1255 dbSNP
rs1366457454 1259 dbSNP
rs142324082 1263 dbSNP
rs138408339 1273 dbSNP
rs1318024861 1275 dbSNP
rs1197883065 1281 dbSNP
rs756005190 1295 dbSNP
rs1270803634 1297 dbSNP
rs181244136 1305 dbSNP
rs1046100134 1313 dbSNP
rs970332340 1316 dbSNP
rs949667425 1325 dbSNP
rs11551875 1338 dbSNP
rs781239394 1342 dbSNP
rs973818566 1344 dbSNP
rs528846487 1352 dbSNP
rs14205 1361 dbSNP
rs1284353519 1369 dbSNP
rs188426506 1374 dbSNP
rs1170511361 1377 dbSNP
rs528804363 1380 dbSNP
rs988255422 1392 dbSNP
rs1407634550 1393 dbSNP
rs1007925690 1411 dbSNP
rs1350903788 1415 dbSNP
rs936813627 1423 dbSNP
rs925473244 1431 dbSNP
rs955631445 1439 dbSNP
rs1279727813 1450 dbSNP
rs1340523219 1455 dbSNP
rs778364587 1469 dbSNP
rs564811845 1476 dbSNP
rs996991895 1477 dbSNP
rs904022628 1495 dbSNP
rs1399346613 1497 dbSNP
rs1043768310 1500 dbSNP
rs1009621164 1509 dbSNP
rs1288854735 1523 dbSNP
rs892581881 1524 dbSNP
rs185887146 1527 dbSNP
rs976147199 1527 dbSNP
rs1265621276 1531 dbSNP
rs7406 1532 dbSNP
rs1192548274 1537 dbSNP
rs563789864 1546 dbSNP
rs1474045406 1547 dbSNP
rs1164362715 1550 dbSNP
rs1004142634 1556 dbSNP
rs1423130527 1557 dbSNP
rs928564230 1565 dbSNP
rs1044710477 1572 dbSNP
rs948540156 1573 dbSNP
rs541977100 1577 dbSNP
rs1026829048 1579 dbSNP
rs1245367430 1585 dbSNP
rs1283558576 1585 dbSNP
rs181401210 1586 dbSNP
rs961101449 1591 dbSNP
rs1286551365 1593 dbSNP
rs753369741 1595 dbSNP
rs986461795 1601 dbSNP
rs148878615 1632 dbSNP
rs1028536305 1634 dbSNP
rs1188769098 1636 dbSNP
rs1385171164 1636 dbSNP
rs1200721709 1641 dbSNP
rs1477768641 1644 dbSNP
rs1261705274 1645 dbSNP
rs1160818466 1648 dbSNP
rs112847128 1650 dbSNP
rs36104417 1652 dbSNP
rs762484447 1663 dbSNP
rs1452575109 1667 dbSNP
rs1447951544 1677 dbSNP
rs1403671815 1690 dbSNP
rs1022407675 1702 dbSNP
rs1396112760 1708 dbSNP
rs1009715880 1713 dbSNP
rs1380479243 1718 dbSNP
rs892549349 1724 dbSNP
rs1056508992 1738 dbSNP
rs1003515001 1739 dbSNP
rs879586968 1746 dbSNP
rs572795845 1747 dbSNP
rs1044294121 1749 dbSNP
rs1325004782 1758 dbSNP
rs948657366 1763 dbSNP
rs756081622 1769 dbSNP
rs557657265 1775 dbSNP
rs539602874 1782 dbSNP
rs1347139464 1786 dbSNP
rs867272643 1800 dbSNP
rs1242681171 1801 dbSNP
rs190809569 1802 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796040. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' auCGAAGGGUUGUCUAUUUACu 5'
            ||||::|      |||||| 
Target 5' ugGCUUUUCU-----UAAAUG- 3'
 		2 - 17
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_002296 | 3UTR | UUUCAACCCUUAAUCUGAAAACAGAAGACAGUCUUAAUAUAAAUGUACUGUGAAGAAUGCUAUUGAUGUUUAUGGUUUCUGAUUACUUUUCAAAUUUUGAUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_194442 | 3UTR | AAUCUGAAAACAGAAGACAGUCUUAAUAUAAAUGUACUGUGAAGAAUGCUAUUGAUGUUUAUGGUUUCUGAUUACUUUUCAAAUUUUGAUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_194442 | 3UTR | CUUAAUAUAAAUGUACUGUGAAGAAUGCUAUUGAUGUUUAUGGUUUCUGAUUACUUUUCAAAUUUUGAUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_194442 | 3UTR | CAGAAGACAGUCUUAAUAUAAAUGUACUGUGAAGAAUGCUAUUGAUGUUUAUGGUUUCUGAUUACUUUUCAAAUUUUGAUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_194442 | 3UTR | UCUUAAUAUAAAUGUACUGUGAAGAAUGCUAUUGAUGUUUAUGGUUUCUGAUUACUUUUCAAAUUUUGAUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_194442 | 3UTR | CAUUUUAAUGGGAAAUUUUCAACCCUUAAUCUGAAAACAGAAGACAGUCUUAAUAUAAAUGUACUGUGAAGAAUGCUAUUGAUGUUUAUGGUUUCUGAUUACUUUUCAAAUUUUGAUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM796040
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000272163.4 | 3UTR | UUGGCUUUUCUUAAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
128 hsa-miR-4729 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055606 TRUB1 TruB pseudouridine synthase family member 1 2 4
MIRT057816 SLC30A7 solute carrier family 30 member 7 2 2
MIRT061212 MED17 mediator complex subunit 17 2 2
MIRT071507 CALM1 calmodulin 1 2 6
MIRT072873 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 4
MIRT076728 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT087566 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 2 2
MIRT158563 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT175514 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT189775 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT198074 H3F3B H3 histone family member 3B 2 4
MIRT216059 IL6ST interleukin 6 signal transducer 2 10
MIRT219256 RREB1 ras responsive element binding protein 1 2 2
MIRT244716 INIP INTS3 and NABP interacting protein 2 2
MIRT271125 ZNF268 zinc finger protein 268 2 4
MIRT299114 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT303511 NAGK N-acetylglucosamine kinase 2 6
MIRT314695 TMEM167A transmembrane protein 167A 2 4
MIRT334550 AMOTL1 angiomotin like 1 2 4
MIRT441656 DEK DEK proto-oncogene 2 2
MIRT442232 BTD biotinidase 2 2
MIRT442418 LBR lamin B receptor 2 2
MIRT443352 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT444351 KIAA1211 KIAA1211 2 2
MIRT444910 KIAA1841 KIAA1841 2 2
MIRT448407 TNFAIP3 TNF alpha induced protein 3 2 2
MIRT456345 OLIG3 oligodendrocyte transcription factor 3 2 8
MIRT467281 SPNS1 sphingolipid transporter 1 (putative) 2 2
MIRT467925 SLC16A7 solute carrier family 16 member 7 2 2
MIRT468463 SET SET nuclear proto-oncogene 2 2
MIRT469438 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT475947 GXYLT1 glucoside xylosyltransferase 1 2 2
MIRT478069 DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 2 2
MIRT479428 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT484710 RNF11 ring finger protein 11 2 2
MIRT491912 XIAP X-linked inhibitor of apoptosis 2 2
MIRT493551 HSPA5 heat shock protein family A (Hsp70) member 5 2 2
MIRT496126 ARF6 ADP ribosylation factor 6 2 2
MIRT500793 TLK1 tousled like kinase 1 2 6
MIRT504649 RPL9 ribosomal protein L9 2 6
MIRT513847 KCTD15 potassium channel tetramerization domain containing 15 2 4
MIRT519806 ZMYM2 zinc finger MYM-type containing 2 2 4
MIRT521156 SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2 2
MIRT521919 PHIP pleckstrin homology domain interacting protein 2 4
MIRT522402 MYADM myeloid associated differentiation marker 2 4
MIRT526434 PARP15 poly(ADP-ribose) polymerase family member 15 2 4
MIRT526779 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 2
MIRT527864 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528063 OLAH oleoyl-ACP hydrolase 2 2
MIRT528640 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT529586 TMEM220 transmembrane protein 220 2 2
MIRT529810 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT531274 PPIL3 peptidylprolyl isomerase like 3 2 2
MIRT531430 MPZL3 myelin protein zero like 3 2 2
MIRT532141 ZNF331 zinc finger protein 331 2 2
MIRT535825 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT536253 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT537386 FGF2 fibroblast growth factor 2 2 2
MIRT543499 MDM2 MDM2 proto-oncogene 2 4
MIRT543564 RPF2 ribosome production factor 2 homolog 2 4
MIRT544457 KRBOX4 KRAB box domain containing 4 2 2
MIRT544902 DCTPP1 dCTP pyrophosphatase 1 2 2
MIRT545104 RAG1 recombination activating 1 2 2
MIRT546244 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT548287 FAM3C family with sequence similarity 3 member C 2 4
MIRT549268 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT550479 TMEM241 transmembrane protein 241 2 2
MIRT550657 ZFP37 ZFP37 zinc finger protein 2 2
MIRT551807 ITGA1 integrin subunit alpha 1 2 2
MIRT552582 ZFHX3 zinc finger homeobox 3 2 2
MIRT552671 YY1 YY1 transcription factor 2 4
MIRT553044 USP28 ubiquitin specific peptidase 28 2 2
MIRT553602 TM7SF3 transmembrane 7 superfamily member 3 2 2
MIRT553816 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT554618 RPS6KA3 ribosomal protein S6 kinase A3 2 2
MIRT556556 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT558290 DUSP8 dual specificity phosphatase 8 2 2
MIRT558487 DBN1 drebrin 1 2 2
MIRT559313 ATXN1 ataxin 1 2 2
MIRT560704 PRPF4B pre-mRNA processing factor 4B 2 2
MIRT562660 ARHGDIA Rho GDP dissociation inhibitor alpha 2 2
MIRT564158 ZNF117 zinc finger protein 117 2 2
MIRT564614 ZNF703 zinc finger protein 703 2 2
MIRT567236 HSPA1B heat shock protein family A (Hsp70) member 1B 2 2
MIRT568753 DDAH1 dimethylarginine dimethylaminohydrolase 1 2 2
MIRT570780 ZNF83 zinc finger protein 83 2 2
MIRT570919 ZNF138 zinc finger protein 138 2 2
MIRT571254 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT573776 PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 2 2
MIRT574670 HNRNPDL heterogeneous nuclear ribonucleoprotein D like 2 2
MIRT609759 TSPAN14 tetraspanin 14 2 2
MIRT613119 EID1 EP300 interacting inhibitor of differentiation 1 2 2
MIRT614384 FGFBP3 fibroblast growth factor binding protein 3 2 2
MIRT625801 MDC1 mediator of DNA damage checkpoint 1 2 2
MIRT634869 CHD4 chromodomain helicase DNA binding protein 4 2 2
MIRT635723 ALKBH4 alkB homolog 4, lysine demethylase 2 2
MIRT636944 LIMS3 LIM zinc finger domain containing 3 2 2
MIRT637010 LIMS3L LIM zinc finger domain containing 4 2 2
MIRT639357 STPG1 sperm tail PG-rich repeat containing 1 2 2
MIRT640995 PROK2 prokineticin 2 2 2
MIRT641343 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT641495 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT642076 FUT11 fucosyltransferase 11 2 2
MIRT646837 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT648154 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT650020 ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 2 2
MIRT650603 HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2 2
MIRT650624 GNB4 G protein subunit beta 4 2 2
MIRT652677 TIGD2 tigger transposable element derived 2 2 2
MIRT652721 TGFBRAP1 transforming growth factor beta receptor associated protein 1 2 2
MIRT654395 RBFOX2 RNA binding protein, fox-1 homolog 2 2 2
MIRT654659 PSPH phosphoserine phosphatase 2 2
MIRT654771 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 2 2
MIRT655696 NUDT21 nudix hydrolase 21 2 2
MIRT657635 GPRIN3 GPRIN family member 3 2 2
MIRT686214 ZNF267 zinc finger protein 267 2 2
MIRT690315 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT696323 DCAF15 DDB1 and CUL4 associated factor 15 2 2
MIRT697602 YAP1 Yes associated protein 1 2 2
MIRT702188 LYPD3 LY6/PLAUR domain containing 3 2 2
MIRT703577 FBXO9 F-box protein 9 2 2
MIRT707807 TSPAN6 tetraspanin 6 2 2
MIRT715951 CKAP2L cytoskeleton associated protein 2 like 2 2
MIRT716970 CNOT6 CCR4-NOT transcription complex subunit 6 2 2
MIRT718223 DEFB105B defensin beta 105B 2 2
MIRT718243 DEFB105A defensin beta 105A 2 2
MIRT719815 TXNDC17 thioredoxin domain containing 17 2 2
MIRT722082 SMC2 structural maintenance of chromosomes 2 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miR-4729 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4729 Cisplatin 5460033 NSC119875 approved resistant cell line (W1)
hsa-mir-4729 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-4729 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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