miRTarBase - #MIRT443007


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pre-miRNA Information
pre-miRNA hsa-mir-497   
Genomic Coordinates chr17: 7017911 - 7018022
Synonyms MIRN497, hsa-mir-497, MIR497
Description Homo sapiens miR-497 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-497-3p
Sequence 64| CAAACCACACUGUGGUGUUAGA |85
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 17 - 7017957 29233923 MiREDiBase
A-to-I 4 17 - 7017956 29233923 MiREDiBase
A-to-I 20 17 - 7017940 24964909, 25521855, 27229138, 29165639, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1413601274 5 dbSNP
rs1028648384 6 dbSNP
rs1479092960 9 dbSNP
rs1261056598 10 dbSNP
rs997278260 11 dbSNP
rs1324708562 13 dbSNP
rs755634302 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TRIOBP   
Synonyms DFNB28, HRIHFB2122, TAP68, TARA, dJ37E16.4
Description TRIO and F-actin binding protein
Transcript NM_001039141   
Other Transcripts NM_007032 , NM_138632   
Expression
Putative miRNA Targets on TRIOBP
3'UTR of TRIOBP
(miRNA target sites are highlighted)		 
>TRIOBP|NM_001039141|3'UTR
   1 AGGTCCCGCCCAGCTGCAGACCCTCCAGGCTGGAGGACCAGCCGCCCTCCTTCCCTCCTGGATGGAAGTAAAAAGCCAAG
  81 CTTTCTCCCCACCCTCTGTGGGCCACACGTGCACTTGCACCCACCACACACACACACACACACACACACACACACACAGA
 161 CACACAGACACATACGCACACACGTGCACACATGTACACACGGATACACACACACACACACACACTGCATATCTGAGCGC
 241 GCCCCTCGCACTGGGTCTCACCTTGCACCTTCTTCAGGATTTTATATGTGAAGAGATTTTTATATAGATTTTTTTCCTTT
 321 TTTTCCAAAACACTTTATACTTTAAAAAAAAAAAAAAAAAGCAATTCCTGGTGGCTGTGTGCCTCCAACCCTGGTCCCCC
 401 TCTGTCTCCAGCCACCCTCTGCTTGGGCTTCTGAGCTGGTGGCCCTGGCCCAGAGGTCTGGCGGAGGCCCAGGCAGCAGC
 481 CATGGCGGGGTGTCTCTACAGGGGAGAGGCGGGAGCCTGCCACCCTCTTCCTGCCCTACCTCCTACTAACACTTCCTGCC
 561 CCATTTGGACCCGTACCATGGGGCTCAGGACAGAGGGAGCTAGCAGCTGGCCTCCATGGCCCCACAGCCTCCTTCGAGGC
 641 TGTGCTGGGTGCAGAACCGCCAGAGCCACCCAAAAGGTGTTTCTCTTCTGCTCCCTGAACCTCTTAACTTAATAAAACGT
 721 TCCAGCAGCTCTGGTGTCCTAGATGGCTGGCAGAACAGGAATGGAGATTGGGGTTTCTTGAAGTGGCTTCCCCACTCACA
 801 CCCTACCCACACCCCACCCTTCCTAAAGCAGCGGCCTCTAGGCTTCTGAGGGTGGGGCTGAAAATCCAAGGTCTCCCTTA
 881 GTACAGACTGTGACGCCCCCAGTGTGGCTTGCAGGCTAGTGGCAGCGGAAGCATGTGGGAAATAGCAAGTCCAGTCCCAC
 961 CCCAACCTACTGAACCAGCGTCTGCATTTTAACAGGGTGCCCCAGTGATTCACGTGACCTTCAAAGTCTGAGGAGCCCTG
1041 GAGTAGGGCCCAGGGCCCAGGCCTGAGAGAGAGGCCTGGGGCTAAGACTAGCCCTGACCATGACCTTGGGCAAGTCACAC
1121 CCCTCACTGAGCCTCAGTTTGCTTCTCCATCAAATGGGTGTTTTTCTTTCAGTCCCAGTCCTCTCCTGAGGCTTTTCCCA
1201 GAGGTCATGCCCAGCCCTGGGCAGGGGTGAGGGCAGGGTTGTGGCTGCCAGGCACAGGTCCAGCGGGCTGGGAGTCCTCA
1281 CCATGGCTGGCTGTGCTGATTATGGTTGCATGGGGCTGGGAAGAGGTCCCATTTCTGAGCCACAGAAACAGGCCACATCC
1361 AGTAGGGGTCCTGGAAGGCTGTGAGAACCCAGAGGAGACCCTGACCCAGCCTGCAGGTAGAAGACTGCCTTTGGAGGCAG
1441 CTTTGAAAGATGACTCTTCCAGATGGAAGAATCAGGAAGGGCCTTCCCACGTGGAGGCACCAGCAGGAGCAAACGTCCCT
1521 GGTGTGTTCAGGCAAAGAGCCACAGGAGAGTGACCTCGTGGAGTGGGAAGAGATTGTTTCCCATTCCCTTGCCAGGGATT
1601 GGTTGAGGAATGGACAAGGCTTGCAGTTCACGCAAGCCAGTGAAATGCGAGGGGAAGTCTTGGGAGTGGGGTGGAGGAGG
1681 TCATCTGGGAAGGGTGTCCTTGGTCTTAAAAAGAGGCACAAGAGGCCGGGCGCGGTGGCTCTTGCCTATTATCCTAGCAC
1761 TTTGGGAGGCCAAGGCAGGGGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCT
1841 ACTAAAAATACAAAAAATTAGCCAGACGTGGTGCCAAGCACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAAT
1921 CACTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGTGTGACAAGGGCGAAACT
2001 CCATCTCAAAAAAAAAGGGGGAGGGTGGCGCAAGGAGAGGACACCTCTCTCCTGGCCCTGTCGCCATCTTCCCTCATCAA
2081 TAGCTAAAAATGGCAAAGAAGAAAGAGCCAGGACCCCGTGCCATCAAATCCTCCGGCCTTGTGCTGCCCTGTCTCGGCAC
2161 TGCTTGCCTTAGGAGATCAGGAGTGTTCCTAGCCACTGGGAGATGGGATGCCTGCCACTGGCAGCTCTGCCGTCCATCCT
2241 CACCATCCCACCGTCCCCCCAAGACAGCTCTCCATCCCATCCTCTGCCTCCCTTCTAGCCTCAACCTAACTCAGGGCTCC
2321 CCCGTCTCACACCTGGGTTGCAGGAACATCCTCTTCACCAACCCCCCTCCCATCCCTCCTCAGGGCTGCCTAGGGCAGCT
2401 ACAAAAACCAGGCCAGCCTCTGAAAGGTGCTCCACATCTCATTAAAAACCGTGAAATCGCACTGCCCCACTATCAGAATA
2481 GCTCAGAGGAGAAGGTCTGCCAGTACCAAGTGCTGGTGGGGATACGGAGAAGAGCAGCTCCCAGGCGCTGCTGGTGCAAA
2561 TGTGCTTTGTTGCACCCACGGCAGGAAACTGACCAGCTTCTCATCAAGTTAAATACGCATCTACCCTATGGCCTAGCATT
2641 TCCACTCTTGCTTACACATCCAGGAGAAATGAGTCCTTACATGCACAAAAGGATGAGTACCGTAATACTCACATCAGCAA
2721 ATAAACAATACAGCTGTGTGTCAGTAGTAGAATGAATAAATTGTGGTCGATTCATAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agAUUGU-GGUGUCACACCAAAc 5'
            |:||: || |||||||| || 
Target 5' tgTGACGCCCCCAGTGTGGCTTg 3'
 889 - 911 144.00 -23.90
2 
miRNA  3' agauuGUGGUGU-CACACCAAAc 5'
               ||:|| | | ||| ||| 
Target 5' ttctcCATCAAATGGGTGTTTTt 3'
 1143 - 1165 125.00 -7.40
3 
miRNA  3' agaUUGUGGUGUCACACCAAAc 5'
             ||::  | | || ||||| 
Target 5' aggAATG-GAGATTGGGGTTTc 3'
 757 - 777 118.00 -5.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
165617 13 ClinVar
1196758 130 ClinVar
1191856 171 ClinVar
COSN32053410 11 COSMIC
COSN26418953 174 COSMIC
COSN28711990 1006 COSMIC
COSN30170898 1050 COSMIC
COSN26507313 1127 COSMIC
COSN26642845 1276 COSMIC
COSN31590811 1349 COSMIC
COSN28969503 1379 COSMIC
COSN17980197 1510 COSMIC
COSN19169538 1822 COSMIC
COSN29986292 1869 COSMIC
COSN26470199 2286 COSMIC
COSN10030362 2583 COSMIC
COSN15974195 2669 COSMIC
COSN4908813 3316 COSMIC
COSN24019993 3724 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs746511251 8 dbSNP
rs1338609321 9 dbSNP
rs1485985632 11 dbSNP
rs1216649696 12 dbSNP
rs727503531 13 dbSNP
rs1356725002 15 dbSNP
rs775926273 17 dbSNP
rs749778321 18 dbSNP
rs780207870 22 dbSNP
rs769189624 29 dbSNP
rs1339527482 30 dbSNP
rs541068887 31 dbSNP
rs762227205 34 dbSNP
rs1476559860 36 dbSNP
rs1193507133 42 dbSNP
rs377326071 51 dbSNP
rs148196452 53 dbSNP
rs561591855 61 dbSNP
rs781137903 62 dbSNP
rs1025351430 67 dbSNP
rs1397007052 70 dbSNP
rs952367332 77 dbSNP
rs983746510 79 dbSNP
rs749245446 85 dbSNP
rs1196398587 89 dbSNP
rs1412006502 94 dbSNP
rs1204398327 95 dbSNP
rs1251136319 95 dbSNP
rs528663393 99 dbSNP
rs1482052028 105 dbSNP
rs1281782483 106 dbSNP
rs910979103 112 dbSNP
rs942434693 118 dbSNP
rs1272789714 121 dbSNP
rs977351499 123 dbSNP
rs1336777959 125 dbSNP
rs141483111 130 dbSNP
rs946339530 142 dbSNP
rs1346502960 143 dbSNP
rs1377818765 146 dbSNP
rs565617775 148 dbSNP
rs539566492 150 dbSNP
rs945975022 151 dbSNP
rs1201005838 153 dbSNP
rs1041596822 156 dbSNP
rs1279460814 161 dbSNP
rs1484586106 162 dbSNP
rs928313511 164 dbSNP
rs59525183 171 dbSNP
rs936022324 178 dbSNP
rs569592670 179 dbSNP
rs536645025 180 dbSNP
rs1276044069 187 dbSNP
rs189570014 189 dbSNP
rs995251664 190 dbSNP
rs1478382069 196 dbSNP
rs550083482 199 dbSNP
rs1173581352 201 dbSNP
rs533278828 202 dbSNP
rs1049052227 206 dbSNP
rs1014324196 208 dbSNP
rs1308951353 228 dbSNP
rs1396204886 229 dbSNP
rs1338826831 236 dbSNP
rs1390528270 247 dbSNP
rs1326408114 249 dbSNP
rs762985 252 dbSNP
rs1384545097 255 dbSNP
rs1233291357 261 dbSNP
rs1455507907 261 dbSNP
rs1419928266 262 dbSNP
rs906361850 263 dbSNP
rs1345574464 265 dbSNP
rs5995496 266 dbSNP
rs1004873119 267 dbSNP
rs1019843529 271 dbSNP
rs1207210519 273 dbSNP
rs1275174471 276 dbSNP
rs1005233460 278 dbSNP
rs1017924949 279 dbSNP
rs964157131 284 dbSNP
rs182135404 290 dbSNP
rs1431579681 291 dbSNP
rs552775106 293 dbSNP
rs187152806 294 dbSNP
rs775148483 296 dbSNP
rs996874345 297 dbSNP
rs1318856970 299 dbSNP
rs1194347302 301 dbSNP
rs545444998 309 dbSNP
rs1269671587 310 dbSNP
rs1028314917 315 dbSNP
rs538003991 321 dbSNP
rs958378694 323 dbSNP
rs1165423351 334 dbSNP
rs989559126 339 dbSNP
rs1193010784 341 dbSNP
rs1021881876 343 dbSNP
rs563635623 346 dbSNP
rs1186335692 348 dbSNP
rs922795648 349 dbSNP
rs1253969844 351 dbSNP
rs1169777306 352 dbSNP
rs967205593 353 dbSNP
rs977535957 361 dbSNP
rs191647106 362 dbSNP
rs928594297 364 dbSNP
rs1341610684 367 dbSNP
rs763651718 370 dbSNP
rs1236728153 371 dbSNP
rs991142406 376 dbSNP
rs1293835125 381 dbSNP
rs543060263 382 dbSNP
rs531416536 391 dbSNP
rs915547891 392 dbSNP
rs1368147764 400 dbSNP
rs776059327 403 dbSNP
rs146280215 406 dbSNP
rs994018748 411 dbSNP
rs1395313637 412 dbSNP
rs887281327 414 dbSNP
rs1218410931 416 dbSNP
rs1235083677 416 dbSNP
rs1324906380 416 dbSNP
rs1348782723 416 dbSNP
rs1365286901 416 dbSNP
rs139675202 416 dbSNP
rs3041692 416 dbSNP
rs3838159 416 dbSNP
rs546439864 416 dbSNP
rs556912268 416 dbSNP
rs577703827 416 dbSNP
rs762511717 416 dbSNP
rs528824447 423 dbSNP
rs1224910890 424 dbSNP
rs1267458516 425 dbSNP
rs1005452242 431 dbSNP
rs563550617 432 dbSNP
rs1041217079 437 dbSNP
rs1359369293 439 dbSNP
rs1174977374 448 dbSNP
rs901454356 455 dbSNP
rs997073223 459 dbSNP
rs1410574511 462 dbSNP
rs1431775400 462 dbSNP
rs1183385941 466 dbSNP
rs1472515177 468 dbSNP
rs1250248275 480 dbSNP
rs529144470 490 dbSNP
rs765773784 492 dbSNP
rs1255605418 515 dbSNP
rs1208331097 519 dbSNP
rs1251289673 526 dbSNP
rs750957974 527 dbSNP
rs1318987211 536 dbSNP
rs1286025886 538 dbSNP
rs1228785813 539 dbSNP
rs1349793753 543 dbSNP
rs776072686 546 dbSNP
rs1286445382 551 dbSNP
rs1416069432 556 dbSNP
rs1011417680 558 dbSNP
rs556711691 562 dbSNP
rs1301789698 565 dbSNP
rs867593871 572 dbSNP
rs967191892 573 dbSNP
rs1346617636 589 dbSNP
rs977247743 598 dbSNP
rs1457103340 599 dbSNP
rs1189833176 602 dbSNP
rs1035471624 607 dbSNP
rs547211895 611 dbSNP
rs139376050 613 dbSNP
rs1180216224 614 dbSNP
rs532606876 632 dbSNP
rs759100967 639 dbSNP
rs926106891 641 dbSNP
rs1209110593 644 dbSNP
rs28672373 646 dbSNP
rs1328282587 649 dbSNP
rs1167277060 654 dbSNP
rs991342052 657 dbSNP
rs549160153 658 dbSNP
rs1322283173 660 dbSNP
rs930959265 665 dbSNP
rs984184128 666 dbSNP
rs1393791510 673 dbSNP
rs908311338 673 dbSNP
rs1363627452 677 dbSNP
rs1320878013 678 dbSNP
rs766667387 679 dbSNP
rs551409242 684 dbSNP
rs1391716788 685 dbSNP
rs569671209 692 dbSNP
rs1368413968 693 dbSNP
rs1289399895 698 dbSNP
rs919352505 707 dbSNP
rs142651342 715 dbSNP
rs1188214169 735 dbSNP
rs11546530 738 dbSNP
rs183850829 739 dbSNP
rs534642955 746 dbSNP
rs565643863 759 dbSNP
rs1010945002 760 dbSNP
rs112861769 767 dbSNP
rs1331345919 776 dbSNP
rs1216505674 778 dbSNP
rs577723541 785 dbSNP
rs79524274 786 dbSNP
rs1485212654 787 dbSNP
rs1039631532 790 dbSNP
rs1362610004 794 dbSNP
rs1003552732 797 dbSNP
rs1035505729 799 dbSNP
rs997875306 804 dbSNP
rs557393102 807 dbSNP
rs1463564907 808 dbSNP
rs1390824527 810 dbSNP
rs902965303 827 dbSNP
rs575684169 828 dbSNP
rs1475074432 833 dbSNP
rs1186812637 842 dbSNP
rs1200723038 853 dbSNP
rs1012793738 855 dbSNP
rs998560305 862 dbSNP
rs1022915134 871 dbSNP
rs1266557037 883 dbSNP
rs952720113 886 dbSNP
rs983832842 893 dbSNP
rs1415153334 895 dbSNP
rs543023219 896 dbSNP
rs150011297 897 dbSNP
rs1344075870 907 dbSNP
rs1305251951 918 dbSNP
rs573566948 920 dbSNP
rs1330929928 926 dbSNP
rs922774859 944 dbSNP
rs540887590 951 dbSNP
rs972025736 968 dbSNP
rs1307430047 969 dbSNP
rs1304481723 971 dbSNP
rs932841687 975 dbSNP
rs919239572 976 dbSNP
rs781322207 985 dbSNP
rs1196505779 986 dbSNP
rs1413887493 987 dbSNP
rs1473498007 988 dbSNP
rs866851426 991 dbSNP
rs1050347843 992 dbSNP
rs1180818957 1000 dbSNP
rs1481815408 1001 dbSNP
rs1280261174 1003 dbSNP
rs915517086 1005 dbSNP
rs551106291 1006 dbSNP
rs1352497741 1008 dbSNP
rs984865719 1010 dbSNP
rs1351642783 1011 dbSNP
rs1224529803 1012 dbSNP
rs145222008 1018 dbSNP
rs1408052197 1020 dbSNP
rs941206073 1026 dbSNP
rs1404162209 1027 dbSNP
rs1039918616 1028 dbSNP
rs902496356 1030 dbSNP
rs763949824 1034 dbSNP
rs1056438238 1038 dbSNP
rs895226244 1045 dbSNP
rs1012741713 1048 dbSNP
rs1023207635 1051 dbSNP
rs933882597 1051 dbSNP
rs534691356 1062 dbSNP
rs866298205 1063 dbSNP
rs571195430 1073 dbSNP
rs1005858849 1079 dbSNP
rs1015263222 1080 dbSNP
rs1032727969 1081 dbSNP
rs1473400758 1083 dbSNP
rs1210951640 1086 dbSNP
rs148722598 1087 dbSNP
rs1268023926 1090 dbSNP
rs1406659119 1107 dbSNP
rs1013095923 1109 dbSNP
rs1284798035 1111 dbSNP
rs976409871 1113 dbSNP
rs1023539718 1114 dbSNP
rs1215197562 1115 dbSNP
rs1338924772 1120 dbSNP
rs922387514 1121 dbSNP
rs1322873069 1123 dbSNP
rs1436967101 1125 dbSNP
rs953756071 1127 dbSNP
rs1455520084 1128 dbSNP
rs1415875050 1131 dbSNP
rs1433884005 1133 dbSNP
rs1310908364 1138 dbSNP
rs1372172587 1139 dbSNP
rs985673505 1142 dbSNP
rs1163323185 1143 dbSNP
rs1227796960 1143 dbSNP
rs1229349713 1143 dbSNP
rs1291310527 1143 dbSNP
rs1299954478 1143 dbSNP
rs1354381632 1143 dbSNP
rs1453767049 1143 dbSNP
rs147418975 1143 dbSNP
rs57293518 1143 dbSNP
rs59251416 1143 dbSNP
rs767976802 1143 dbSNP
rs796408287 1143 dbSNP
rs868480352 1143 dbSNP
rs878858922 1143 dbSNP
rs878916780 1143 dbSNP
rs1443258713 1144 dbSNP
rs1297803058 1146 dbSNP
rs1364747119 1147 dbSNP
rs1296510193 1148 dbSNP
rs1428458939 1149 dbSNP
rs1371308633 1154 dbSNP
rs1169964020 1156 dbSNP
rs915365291 1156 dbSNP
rs1187062021 1158 dbSNP
rs1449640734 1158 dbSNP
rs947006061 1158 dbSNP
rs1247777640 1160 dbSNP
rs1304821326 1160 dbSNP
rs58391528 1160 dbSNP
rs982096976 1160 dbSNP
rs1042993815 1162 dbSNP
rs536629968 1162 dbSNP
rs1205960726 1164 dbSNP
rs1347716915 1164 dbSNP
rs1295746761 1166 dbSNP
rs746717135 1166 dbSNP
rs756521773 1166 dbSNP
rs766683068 1168 dbSNP
rs776822941 1168 dbSNP
rs923950327 1168 dbSNP
rs1309249386 1170 dbSNP
rs1369545656 1170 dbSNP
rs868758708 1170 dbSNP
rs1056388787 1172 dbSNP
rs1415851122 1172 dbSNP
rs1277295765 1174 dbSNP
rs1426251351 1174 dbSNP
rs755129866 1174 dbSNP
rs776141551 1174 dbSNP
rs865875994 1174 dbSNP
rs1182969703 1176 dbSNP
rs1254675522 1176 dbSNP
rs895263895 1176 dbSNP
rs73883919 1178 dbSNP
rs1272711382 1180 dbSNP
rs1204834915 1182 dbSNP
rs984750065 1182 dbSNP
rs796717164 1183 dbSNP
rs1231903880 1184 dbSNP
rs1479389647 1186 dbSNP
rs1194895601 1187 dbSNP
rs1253066037 1188 dbSNP
rs909314272 1189 dbSNP
rs1321331953 1190 dbSNP
rs1409880081 1192 dbSNP
rs1453793800 1192 dbSNP
rs61448175 1194 dbSNP
rs1391837000 1195 dbSNP
rs1044257126 1197 dbSNP
rs1359384597 1198 dbSNP
rs563377986 1202 dbSNP
rs975296892 1203 dbSNP
rs1414801395 1206 dbSNP
rs1160600088 1209 dbSNP
rs1472571699 1210 dbSNP
rs1352917409 1214 dbSNP
rs921095687 1218 dbSNP
rs530546283 1220 dbSNP
rs764327569 1220 dbSNP
rs779068364 1220 dbSNP
rs879109627 1221 dbSNP
rs1237188633 1222 dbSNP
rs878884025 1222 dbSNP
rs1166998394 1224 dbSNP
rs1362575959 1224 dbSNP
rs143929428 1224 dbSNP
rs1457127379 1224 dbSNP
rs372674069 1224 dbSNP
rs59571998 1224 dbSNP
rs772615495 1224 dbSNP
rs866586763 1228 dbSNP
rs1424531733 1229 dbSNP
rs1413320148 1230 dbSNP
rs1370328901 1233 dbSNP
rs1439387460 1241 dbSNP
rs1491468945 1243 dbSNP
rs888238520 1245 dbSNP
rs924494455 1248 dbSNP
rs1129448 1258 dbSNP
rs12628490 1260 dbSNP
rs1271857860 1262 dbSNP
rs1321833841 1264 dbSNP
rs535698170 1266 dbSNP
rs555882466 1267 dbSNP
rs528081729 1269 dbSNP
rs1047326 1278 dbSNP
rs1434918591 1288 dbSNP
rs953787215 1297 dbSNP
rs1191689001 1303 dbSNP
rs1383424108 1306 dbSNP
rs1295855784 1307 dbSNP
rs571468382 1309 dbSNP
rs1044606130 1321 dbSNP
rs79640513 1325 dbSNP
rs1003006655 1326 dbSNP
rs556906642 1327 dbSNP
rs1391087589 1329 dbSNP
rs1188952951 1338 dbSNP
rs1427752246 1343 dbSNP
rs1417117662 1347 dbSNP
rs77047691 1349 dbSNP
rs886110625 1351 dbSNP
rs1463276633 1358 dbSNP
rs1259534090 1359 dbSNP
rs200741206 1359 dbSNP
rs1165889554 1360 dbSNP
rs1026569212 1361 dbSNP
rs201541475 1361 dbSNP
rs113424764 1362 dbSNP
rs1301368636 1362 dbSNP
rs1367521740 1362 dbSNP
rs1431765767 1362 dbSNP
rs1491074918 1362 dbSNP
rs35269997 1362 dbSNP
rs551329239 1362 dbSNP
rs879016246 1362 dbSNP
rs1393899335 1363 dbSNP
rs1459898061 1364 dbSNP
rs1168237463 1365 dbSNP
rs1460685011 1372 dbSNP
rs1371076537 1378 dbSNP
rs78102894 1378 dbSNP
rs1327463056 1379 dbSNP
rs1430626882 1380 dbSNP
rs1268856907 1381 dbSNP
rs1381754558 1386 dbSNP
rs1008815685 1391 dbSNP
rs865919473 1395 dbSNP
rs985588978 1398 dbSNP
rs1194836777 1407 dbSNP
rs1337066377 1408 dbSNP
rs1273370063 1414 dbSNP
rs1022463058 1415 dbSNP
rs1312109039 1417 dbSNP
rs1411701835 1418 dbSNP
rs968587226 1419 dbSNP
rs1333557776 1420 dbSNP
rs978274975 1423 dbSNP
rs964864046 1428 dbSNP
rs868047222 1434 dbSNP
rs1211200801 1437 dbSNP
rs975226010 1437 dbSNP
rs924234947 1438 dbSNP
rs939587382 1442 dbSNP
rs924546931 1448 dbSNP
rs1047362 1450 dbSNP
rs934563072 1452 dbSNP
rs1054070873 1461 dbSNP
rs1251848332 1475 dbSNP
rs1214983409 1477 dbSNP
rs1180487513 1481 dbSNP
rs1435712325 1482 dbSNP
rs1257910289 1485 dbSNP
rs914218798 1486 dbSNP
rs1461176966 1488 dbSNP
rs1476053672 1491 dbSNP
rs1261692579 1494 dbSNP
rs992133118 1498 dbSNP
rs1412575851 1499 dbSNP
rs916558295 1505 dbSNP
rs948165703 1506 dbSNP
rs1049579620 1509 dbSNP
rs1292343057 1511 dbSNP
rs887862474 1512 dbSNP
rs1003060621 1518 dbSNP
rs1047897942 1522 dbSNP
rs1385756584 1525 dbSNP
rs941231857 1526 dbSNP
rs368067206 1527 dbSNP
rs1006476594 1528 dbSNP
rs144584317 1529 dbSNP
rs965082474 1530 dbSNP
rs1415736681 1534 dbSNP
rs1293529225 1538 dbSNP
rs1354364011 1540 dbSNP
rs555108172 1559 dbSNP
rs1029351429 1562 dbSNP
rs541478522 1564 dbSNP
rs1204539234 1565 dbSNP
rs1006647782 1567 dbSNP
rs1284251822 1568 dbSNP
rs1022496432 1575 dbSNP
rs1282005500 1577 dbSNP
rs1358617806 1584 dbSNP
rs1486548423 1591 dbSNP
rs767863524 1592 dbSNP
rs1245459629 1595 dbSNP
rs1380874999 1598 dbSNP
rs115338330 1608 dbSNP
rs990016151 1612 dbSNP
rs1484851870 1640 dbSNP
rs978688794 1642 dbSNP
rs1184212590 1646 dbSNP
rs1364507041 1647 dbSNP
rs1031100153 1651 dbSNP
rs147872289 1654 dbSNP
rs193262683 1655 dbSNP
rs1397353357 1657 dbSNP
rs916589509 1659 dbSNP
rs370094888 1665 dbSNP
rs547892573 1665 dbSNP
rs1190896436 1666 dbSNP
rs948085895 1668 dbSNP
rs1242017213 1670 dbSNP
rs112271606 1677 dbSNP
rs909314698 1678 dbSNP
rs1290614709 1690 dbSNP
rs1047964913 1695 dbSNP
rs1047436 1702 dbSNP
rs1357533846 1703 dbSNP
rs1047442 1704 dbSNP
rs1047443 1707 dbSNP
rs1374025764 1721 dbSNP
rs1393970610 1728 dbSNP
rs1330451610 1731 dbSNP
rs1230300133 1737 dbSNP
rs1362348365 1738 dbSNP
rs185419744 1740 dbSNP
rs1428479754 1744 dbSNP
rs1332763409 1748 dbSNP
rs1237658020 1750 dbSNP
rs1423519752 1751 dbSNP
rs942143104 1763 dbSNP
rs1268341007 1766 dbSNP
rs1038363222 1777 dbSNP
rs1430040827 1779 dbSNP
rs1338674735 1794 dbSNP
rs1349893914 1806 dbSNP
rs1188997348 1809 dbSNP
rs1036876871 1812 dbSNP
rs750400461 1816 dbSNP
rs1345442646 1818 dbSNP
rs1247871672 1820 dbSNP
rs544769225 1821 dbSNP
rs1050963327 1824 dbSNP
rs1254109947 1831 dbSNP
rs1206076657 1834 dbSNP
rs778956807 1851 dbSNP
rs1251461342 1858 dbSNP
rs1437317061 1860 dbSNP
rs1007006228 1862 dbSNP
rs1254948105 1866 dbSNP
rs1347015927 1876 dbSNP
rs1283906146 1879 dbSNP
rs1455133607 1879 dbSNP
rs1043379669 1885 dbSNP
rs562985056 1890 dbSNP
rs1353566667 1891 dbSNP
rs1327264242 1892 dbSNP
rs1031498482 1893 dbSNP
rs530243072 1913 dbSNP
rs1362001024 1914 dbSNP
rs542270914 1916 dbSNP
rs999208959 1920 dbSNP
rs1414197456 1928 dbSNP
rs1182987845 1937 dbSNP
rs1390328395 1941 dbSNP
rs1328757872 1942 dbSNP
rs1202158721 1944 dbSNP
rs1372499664 1945 dbSNP
rs7287039 1946 dbSNP
rs969971677 1950 dbSNP
rs780052549 1953 dbSNP
rs1013700356 1966 dbSNP
rs1023882921 1970 dbSNP
rs1223922552 1973 dbSNP
rs969651053 1975 dbSNP
rs985227480 1977 dbSNP
rs528045845 1978 dbSNP
rs55649555 1986 dbSNP
rs907585850 1989 dbSNP
rs1336500910 1994 dbSNP
rs771924568 1998 dbSNP
rs571496797 1999 dbSNP
rs972101564 2004 dbSNP
rs151100741 2015 dbSNP
rs188367676 2019 dbSNP
rs1406027538 2033 dbSNP
rs1037846612 2034 dbSNP
rs34771121 2036 dbSNP
rs1473263841 2037 dbSNP
rs1243465835 2047 dbSNP
rs933844537 2057 dbSNP
rs746657203 2060 dbSNP
rs932236903 2063 dbSNP
rs146246644 2067 dbSNP
rs1215842736 2069 dbSNP
rs911152659 2071 dbSNP
rs1304257277 2073 dbSNP
rs1229620192 2074 dbSNP
rs942619252 2075 dbSNP
rs1314785710 2076 dbSNP
rs1367942205 2083 dbSNP
rs999446484 2083 dbSNP
rs1290013024 2086 dbSNP
rs1453719861 2089 dbSNP
rs768240701 2090 dbSNP
rs903480876 2094 dbSNP
rs1167023514 2095 dbSNP
rs893867801 2110 dbSNP
rs1182739785 2114 dbSNP
rs550743401 2121 dbSNP
rs1366232579 2123 dbSNP
rs1052171578 2136 dbSNP
rs1485510239 2141 dbSNP
rs896239595 2142 dbSNP
rs1396058866 2144 dbSNP
rs1461470541 2147 dbSNP
rs1258364599 2148 dbSNP
rs1325142862 2162 dbSNP
rs1365330955 2164 dbSNP
rs1223210543 2176 dbSNP
rs1359686974 2178 dbSNP
rs1290638012 2184 dbSNP
rs1013733030 2193 dbSNP
rs1244196339 2195 dbSNP
rs1383836178 2202 dbSNP
rs111882841 2215 dbSNP
rs776175350 2216 dbSNP
rs761270969 2217 dbSNP
rs536452003 2219 dbSNP
rs1295358546 2224 dbSNP
rs1001451987 2229 dbSNP
rs1006446973 2231 dbSNP
rs1016678756 2234 dbSNP
rs1374523100 2237 dbSNP
rs1170883747 2240 dbSNP
rs1335585034 2242 dbSNP
rs866227487 2244 dbSNP
rs972049214 2249 dbSNP
rs983091545 2251 dbSNP
rs1487170743 2263 dbSNP
rs1457798057 2267 dbSNP
rs1490381439 2274 dbSNP
rs1206236457 2277 dbSNP
rs907636228 2281 dbSNP
rs963145120 2281 dbSNP
rs974000591 2283 dbSNP
rs141022698 2284 dbSNP
rs1419484664 2293 dbSNP
rs932261344 2301 dbSNP
rs1052031665 2302 dbSNP
rs769314673 2303 dbSNP
rs566985352 2304 dbSNP
rs1455315993 2312 dbSNP
rs1411825893 2320 dbSNP
rs1052358649 2322 dbSNP
rs893921912 2333 dbSNP
rs1010972932 2334 dbSNP
rs150115336 2337 dbSNP
rs1371233394 2338 dbSNP
rs942614751 2343 dbSNP
rs1480737100 2349 dbSNP
rs779212974 2354 dbSNP
rs1196662024 2355 dbSNP
rs1439193340 2361 dbSNP
rs1195569233 2372 dbSNP
rs979340158 2372 dbSNP
rs138428573 2373 dbSNP
rs1001734812 2375 dbSNP
rs1224597255 2382 dbSNP
rs1315015232 2387 dbSNP
rs773652971 2388 dbSNP
rs1035624549 2389 dbSNP
rs1232886731 2390 dbSNP
rs1310754442 2392 dbSNP
rs935038266 2395 dbSNP
rs959914493 2396 dbSNP
rs1240417332 2398 dbSNP
rs1004578792 2400 dbSNP
rs867480395 2407 dbSNP
rs1014578167 2416 dbSNP
rs1338476731 2425 dbSNP
rs183719668 2438 dbSNP
rs748538286 2447 dbSNP
rs1487513931 2451 dbSNP
rs896270778 2452 dbSNP
rs544617151 2454 dbSNP
rs1173616769 2468 dbSNP
rs1470907084 2472 dbSNP
rs963496879 2475 dbSNP
rs973171477 2479 dbSNP
rs1416953290 2482 dbSNP
rs1213393082 2487 dbSNP
rs556444376 2488 dbSNP
rs763456747 2490 dbSNP
rs1204783033 2502 dbSNP
rs1258635295 2510 dbSNP
rs1261863981 2519 dbSNP
rs1206937046 2521 dbSNP
rs574666310 2528 dbSNP
rs766761745 2534 dbSNP
rs1186737823 2536 dbSNP
rs987578254 2541 dbSNP
rs1260239462 2542 dbSNP
rs1411052712 2552 dbSNP
rs188828418 2574 dbSNP
rs905318620 2577 dbSNP
rs1006890260 2579 dbSNP
rs560634518 2580 dbSNP
rs898076125 2590 dbSNP
rs1381919445 2606 dbSNP
rs993519289 2610 dbSNP
rs572632148 2611 dbSNP
rs935572578 2617 dbSNP
rs1402409655 2650 dbSNP
rs1030323156 2651 dbSNP
rs1157485114 2652 dbSNP
rs954788998 2665 dbSNP
rs540222390 2667 dbSNP
rs564770265 2668 dbSNP
rs1375834372 2669 dbSNP
rs937201925 2670 dbSNP
rs1018533438 2672 dbSNP
rs751927418 2675 dbSNP
rs1448097638 2676 dbSNP
rs1056972446 2678 dbSNP
rs895757496 2687 dbSNP
rs979674368 2688 dbSNP
rs1292847165 2689 dbSNP
rs140243749 2696 dbSNP
rs1375657153 2698 dbSNP
rs898842065 2702 dbSNP
rs1432724106 2711 dbSNP
rs1306930139 2713 dbSNP
rs994873470 2714 dbSNP
rs1237132203 2715 dbSNP
rs935237779 2721 dbSNP
rs1367018429 2727 dbSNP
rs759785585 2727 dbSNP
rs917561327 2732 dbSNP
rs1423629104 2736 dbSNP
rs949139060 2746 dbSNP
rs181260394 2747 dbSNP
rs1476025577 2750 dbSNP
rs1044784733 2753 dbSNP
rs112317694 2757 dbSNP
rs371946571 2758 dbSNP
rs1019052371 2760 dbSNP
rs956991720 2767 dbSNP
rs745646806 2771 dbSNP
rs942251300 2773 dbSNP
rs1038257026 2775 dbSNP
rs988360485 2776 dbSNP
rs915439025 2777 dbSNP
rs562792849 2779 dbSNP
rs753521519 2779 dbSNP
rs1269564580 2795 dbSNP
rs1346793258 2796 dbSNP
rs946755764 2796 dbSNP
rs898107334 2799 dbSNP
rs563623545 2801 dbSNP
rs376675715 2805 dbSNP
rs1331277557 2808 dbSNP
rs1395512211 2815 dbSNP
rs1419393462 2820 dbSNP
rs548436365 2822 dbSNP
rs1007966100 2823 dbSNP
rs939396890 2824 dbSNP
rs1198872447 2826 dbSNP
rs41280039 2830 dbSNP
rs1234859997 2834 dbSNP
rs969190937 2841 dbSNP
rs895641400 2844 dbSNP
rs1196614233 2849 dbSNP
rs1462675231 2854 dbSNP
rs940474495 2854 dbSNP
rs534078240 2867 dbSNP
rs1032109331 2868 dbSNP
rs1280969255 2870 dbSNP
rs1442532294 2877 dbSNP
rs780903787 2882 dbSNP
rs1304742282 2886 dbSNP
rs552532353 2887 dbSNP
rs756217563 2896 dbSNP
rs1431548091 2907 dbSNP
rs917587646 2917 dbSNP
rs1276085677 2919 dbSNP
rs1308954077 2921 dbSNP
rs1469828182 2923 dbSNP
rs1232025250 2929 dbSNP
rs1204775144 2930 dbSNP
rs1256916773 2934 dbSNP
rs1176619014 2936 dbSNP
rs970451266 2938 dbSNP
rs1195454990 2940 dbSNP
rs1253474757 2941 dbSNP
rs1477581181 2951 dbSNP
rs1202451114 2955 dbSNP
rs1189309001 2958 dbSNP
rs1421381231 2961 dbSNP
rs1372941255 2973 dbSNP
rs1410780240 2975 dbSNP
rs1285778248 2976 dbSNP
rs1223941084 2978 dbSNP
rs980841381 2980 dbSNP
rs1398224894 2981 dbSNP
rs1454959630 2982 dbSNP
rs1463046318 2983 dbSNP
rs1336597266 2988 dbSNP
rs1465003951 2990 dbSNP
rs1327172913 2992 dbSNP
rs1362771366 2993 dbSNP
rs570712649 2996 dbSNP
rs1394321832 3005 dbSNP
rs926415926 3009 dbSNP
rs1272356656 3013 dbSNP
rs1019105516 3014 dbSNP
rs1363056261 3017 dbSNP
rs1214848776 3022 dbSNP
rs1182864710 3026 dbSNP
rs1243279363 3026 dbSNP
rs1482245654 3026 dbSNP
rs956872539 3026 dbSNP
rs988244045 3026 dbSNP
rs367623284 3031 dbSNP
rs376093216 3033 dbSNP
rs1283485238 3034 dbSNP
rs919401374 3035 dbSNP
rs1360555369 3038 dbSNP
rs929552981 3040 dbSNP
rs1052051446 3042 dbSNP
rs980818071 3046 dbSNP
rs750379113 3048 dbSNP
rs113011245 3049 dbSNP
rs1430165842 3052 dbSNP
rs1358823890 3055 dbSNP
rs1165663898 3056 dbSNP
rs779872630 3059 dbSNP
rs373238447 3075 dbSNP
rs908591448 3077 dbSNP
rs746819766 3081 dbSNP
rs868861509 3082 dbSNP
rs768528002 3092 dbSNP
rs956502514 3094 dbSNP
rs780657899 3095 dbSNP
rs1421674442 3098 dbSNP
rs1291496159 3099 dbSNP
rs553991865 3101 dbSNP
rs1296971801 3105 dbSNP
rs1165827641 3110 dbSNP
rs1214533503 3117 dbSNP
rs930538809 3121 dbSNP
rs747810427 3122 dbSNP
rs1024886100 3130 dbSNP
rs1417250212 3131 dbSNP
rs1365261451 3132 dbSNP
rs971031734 3136 dbSNP
rs1456231842 3137 dbSNP
rs980490763 3142 dbSNP
rs1170997448 3149 dbSNP
rs1040117046 3153 dbSNP
rs926252535 3154 dbSNP
rs963177837 3159 dbSNP
rs1201039517 3161 dbSNP
rs973110316 3164 dbSNP
rs1480551441 3165 dbSNP
rs572886272 3166 dbSNP
rs1266294803 3167 dbSNP
rs1208401659 3168 dbSNP
rs919002464 3174 dbSNP
rs1252280177 3175 dbSNP
rs865869153 3191 dbSNP
rs542468556 3193 dbSNP
rs1285269721 3204 dbSNP
rs929500760 3214 dbSNP
rs1476034360 3221 dbSNP
rs1338043216 3223 dbSNP
rs1234742864 3224 dbSNP
rs1051917293 3227 dbSNP
rs1355006993 3228 dbSNP
rs1022865776 3241 dbSNP
rs1393378289 3248 dbSNP
rs145284375 3250 dbSNP
rs1298536985 3251 dbSNP
rs34092065 3258 dbSNP
rs1286207764 3269 dbSNP
rs1002859112 3270 dbSNP
rs1398097467 3271 dbSNP
rs1447373049 3272 dbSNP
rs745575690 3273 dbSNP
rs1469907099 3274 dbSNP
rs76405829 3275 dbSNP
rs544210093 3278 dbSNP
rs960701480 3281 dbSNP
rs769228804 3284 dbSNP
rs1251612566 3289 dbSNP
rs1039051132 3293 dbSNP
rs1456815900 3296 dbSNP
rs992138732 3298 dbSNP
rs908642346 3301 dbSNP
rs904481698 3309 dbSNP
rs137873182 3311 dbSNP
rs1160835815 3317 dbSNP
rs1053167334 3323 dbSNP
rs1445835409 3329 dbSNP
rs530042023 3331 dbSNP
rs548399398 3335 dbSNP
rs1415167734 3336 dbSNP
rs560427517 3338 dbSNP
rs1338581512 3339 dbSNP
rs1009380628 3340 dbSNP
rs1024751720 3342 dbSNP
rs763438071 3343 dbSNP
rs1364077135 3349 dbSNP
rs868690170 3350 dbSNP
rs1438176369 3351 dbSNP
rs1245375913 3362 dbSNP
rs944389572 3363 dbSNP
rs527488876 3369 dbSNP
rs1254164703 3375 dbSNP
rs1207030174 3377 dbSNP
rs1351643078 3380 dbSNP
rs1377618895 3380 dbSNP
rs1285626633 3382 dbSNP
rs1040002664 3384 dbSNP
rs1316911516 3385 dbSNP
rs1351174698 3385 dbSNP
rs963409581 3386 dbSNP
rs1409396585 3390 dbSNP
rs892238821 3403 dbSNP
rs1383469159 3408 dbSNP
rs1009726607 3409 dbSNP
rs865994134 3415 dbSNP
rs1297142626 3417 dbSNP
rs1167939081 3422 dbSNP
rs1313051157 3429 dbSNP
rs973062862 3432 dbSNP
rs1417494536 3435 dbSNP
rs1050260 3439 dbSNP
rs1043933153 3440 dbSNP
rs1472748750 3443 dbSNP
rs3171656 3445 dbSNP
rs1351386763 3457 dbSNP
rs528196112 3462 dbSNP
rs574972054 3469 dbSNP
rs189865114 3470 dbSNP
rs943634667 3472 dbSNP
rs960921429 3477 dbSNP
rs767951570 3478 dbSNP
rs975363324 3487 dbSNP
rs926220974 3491 dbSNP
rs551483095 3504 dbSNP
rs774912216 3504 dbSNP
rs778712456 3508 dbSNP
rs961494214 3508 dbSNP
rs549792320 3521 dbSNP
rs1367112554 3526 dbSNP
rs568411782 3529 dbSNP
rs752897615 3535 dbSNP
rs1389063064 3537 dbSNP
rs535787164 3543 dbSNP
rs761041421 3544 dbSNP
rs950110235 3545 dbSNP
rs369769016 3553 dbSNP
rs764254090 3561 dbSNP
rs1046234992 3565 dbSNP
rs1221994734 3575 dbSNP
rs554055171 3581 dbSNP
rs1287482244 3587 dbSNP
rs1197409679 3588 dbSNP
rs1002134767 3591 dbSNP
rs1034052274 3593 dbSNP
rs899063142 3598 dbSNP
rs994533105 3599 dbSNP
rs913561176 3610 dbSNP
rs15691 3612 dbSNP
rs1435335127 3614 dbSNP
rs1329654481 3616 dbSNP
rs1331298841 3626 dbSNP
rs950464789 3634 dbSNP
rs530463327 3635 dbSNP
rs1330389516 3636 dbSNP
rs1376957601 3637 dbSNP
rs1446012834 3640 dbSNP
rs903580859 3644 dbSNP
rs774229733 3647 dbSNP
rs1019117607 3663 dbSNP
rs182483906 3666 dbSNP
rs1055288073 3671 dbSNP
rs1372955880 3674 dbSNP
rs965278514 3675 dbSNP
rs558919595 3678 dbSNP
rs1196706745 3681 dbSNP
rs144097527 3693 dbSNP
rs1343218990 3694 dbSNP
rs1342524815 3698 dbSNP
rs1197743779 3699 dbSNP
rs1273862047 3700 dbSNP
rs926223608 3703 dbSNP
rs1457332151 3704 dbSNP
rs777309049 3711 dbSNP
rs1329863600 3713 dbSNP
rs1455078893 3717 dbSNP
rs536130387 3718 dbSNP
rs1175529169 3720 dbSNP
rs550155929 3721 dbSNP
rs746555762 3725 dbSNP
rs750641693 3728 dbSNP
rs1160201974 3736 dbSNP
rs1440032924 3737 dbSNP
rs897155801 3741 dbSNP
rs1325738102 3744 dbSNP
rs1198676729 3745 dbSNP
rs1462600983 3745 dbSNP
rs1376280894 3750 dbSNP
rs1208888616 3753 dbSNP
rs1476862479 3759 dbSNP
rs1169266712 3762 dbSNP
rs1285963243 3768 dbSNP
rs3190556 3776 dbSNP
rs766184446 3783 dbSNP
rs1464613195 3784 dbSNP
rs751537533 3787 dbSNP
rs950141232 3788 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000406386.3 | 3UTR | UUGGCUGCAAGUUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells -0.591 1.5e-3 -0.354 4.9e-2 23 Click to see details
GSE28544 Breast cancer 0.551 2.6e-3 0.551 2.6e-3 24 Click to see details
GSE32688 Pancreatic cancer 0.263 7.3e-2 0.364 2.0e-2 32 Click to see details
GSE19350 CNS germ cell tumors 0.314 1.6e-1 0.476 5.9e-2 12 Click to see details
GSE38226 Liver fibrosis -0.216 1.7e-1 -0.137 2.8e-1 21 Click to see details
GSE17498 Multiple myeloma -0.131 2.1e-1 -0.063 3.5e-1 40 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.149 2.7e-1 0.054 4.1e-1 20 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.131 2.7e-1 -0.296 7.5e-2 25 Click to see details
GSE21687 Ependynoma primary tumors 0.037 3.9e-1 -0.003 4.9e-1 64 Click to see details
GSE28260 Renal cortex and medulla -0.086 3.9e-1 0.073 4.1e-1 13 Click to see details
GSE26953 Aortic valvular endothelial cells 0.039 4.3e-1 0.210 1.6e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells 0.039 4.3e-1 0.210 1.6e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells 0.039 4.3e-1 0.210 1.6e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
CHOL -0.787 0.03 -0.829 0.02 6 Click to see details
BLCA -0.895 0.05 -1.000 0.5 4 Click to see details
LUAD 0.874 0.06 0.800 0.1 4 Click to see details
KIRP -0.285 0.11 -0.203 0.19 21 Click to see details
BRCA -0.181 0.13 -0.223 0.08 42 Click to see details
LUSC -0.185 0.16 -0.016 0.47 30 Click to see details
PAAD -0.6 0.2 -0.400 0.3 4 Click to see details
STAD -0.078 0.37 -0.003 0.49 21 Click to see details
LIHC -0.061 0.37 -0.011 0.48 30 Click to see details
KICH -0.086 0.38 -0.139 0.31 15 Click to see details
PRAD -0.044 0.39 -0.096 0.26 46 Click to see details
KIRC 0.039 0.4 -0.047 0.38 43 Click to see details
ESCA 0.084 0.41 0.152 0.34 10 Click to see details
HNSC 0.046 0.43 0.146 0.28 18 Click to see details
UCEC -0.029 0.46 -0.188 0.24 16 Click to see details
THCA 0.015 0.46 -0.122 0.21 45 Click to see details
THCA 0.015 0.46 -0.122 0.21 45 Click to see details
THCA 0.015 0.46 -0.122 0.21 45 Click to see details
THCA 0.015 0.46 -0.122 0.21 45 Click to see details
95 hsa-miR-497-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT092955 CYP2U1 cytochrome P450 family 2 subfamily U member 1 2 4
MIRT124568 PRRC2B proline rich coiled-coil 2B 2 2
MIRT125196 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 4
MIRT147296 KPNA2 karyopherin subunit alpha 2 2 8
MIRT163999 KIAA1109 KIAA1109 2 4
MIRT252495 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT357969 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT443007 TRIOBP TRIO and F-actin binding protein 2 2
MIRT443524 NETO1 neuropilin and tolloid like 1 2 2
MIRT443573 EVX2 even-skipped homeobox 2 2 2
MIRT443656 BACH1 BTB domain and CNC homolog 1 2 2
MIRT460670 KRT10 keratin 10 2 8
MIRT464761 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT465032 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT465040 TTC39C tetratricopeptide repeat domain 39C 2 2
MIRT468667 SEC62 SEC62 homolog, preprotein translocation factor 2 2
MIRT473694 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT477618 EFNA3 ephrin A3 2 2
MIRT480506 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT480592 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT486915 ZNF398 zinc finger protein 398 2 6
MIRT487770 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 16
MIRT493265 MDFIC MyoD family inhibitor domain containing 2 2
MIRT495271 SLC1A2 solute carrier family 1 member 2 2 4
MIRT495309 CHST12 carbohydrate sulfotransferase 12 2 2
MIRT496681 DPP6 dipeptidyl peptidase like 6 2 4
MIRT496891 FOXP1 forkhead box P1 2 2
MIRT497330 IRF4 interferon regulatory factor 4 2 2
MIRT498272 KIAA1644 KIAA1644 2 2
MIRT498634 CHD4 chromodomain helicase DNA binding protein 4 2 10
MIRT500581 USP53 ubiquitin specific peptidase 53 2 2
MIRT500751 TMPPE transmembrane protein with metallophosphoesterase domain 2 6
MIRT509668 ZNF354B zinc finger protein 354B 2 10
MIRT510919 PSMA2 proteasome subunit alpha 2 2 4
MIRT519118 CEP76 centrosomal protein 76 2 2
MIRT526193 ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) 2 2
MIRT526746 HLA-DOB major histocompatibility complex, class II, DO beta 2 2
MIRT527270 FBLN2 fibulin 2 2 2
MIRT528198 PLEKHM2 pleckstrin homology and RUN domain containing M2 2 2
MIRT528330 TBC1D22B TBC1 domain family member 22B 2 2
MIRT530346 GABRB3 gamma-aminobutyric acid type A receptor beta3 subunit 2 2
MIRT533627 TMX3 thioredoxin related transmembrane protein 3 2 2
MIRT533738 TMEM200C transmembrane protein 200C 2 2
MIRT533779 TMEM133 transmembrane protein 133 2 2
MIRT534317 SKIDA1 SKI/DACH domain containing 1 2 2
MIRT538438 COG5 component of oligomeric golgi complex 5 2 2
MIRT539156 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT539474 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT539620 SHISA9 shisa family member 9 2 2
MIRT539650 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT540346 OPHN1 oligophrenin 1 2 2
MIRT540412 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 2
MIRT541200 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT541395 CDC27 cell division cycle 27 2 2
MIRT546443 SNX5 sorting nexin 5 2 2
MIRT547369 MSI2 musashi RNA binding protein 2 2 2
MIRT553288 TSPAN3 tetraspanin 3 2 2
MIRT554402 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT557822 FOXN2 forkhead box N2 2 2
MIRT568530 ANP32E acidic nuclear phosphoprotein 32 family member E 2 2
MIRT569508 THYN1 thymocyte nuclear protein 1 2 2
MIRT570707 FAM69A family with sequence similarity 69 member A 2 2
MIRT608376 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT608483 NKTR natural killer cell triggering receptor 2 6
MIRT613533 TRA2B transformer 2 beta homolog 2 2
MIRT616601 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT618166 DUSP18 dual specificity phosphatase 18 2 2
MIRT632059 CEP135 centrosomal protein 135 2 2
MIRT647379 ZDHHC23 zinc finger DHHC-type containing 23 2 2
MIRT648366 POTED POTE ankyrin domain family member D 2 2
MIRT651075 ZNF518B zinc finger protein 518B 2 4
MIRT653618 SLC30A4 solute carrier family 30 member 4 2 2
MIRT653636 SLC30A1 solute carrier family 30 member 1 2 2
MIRT654895 POU2F1 POU class 2 homeobox 1 2 2
MIRT656232 MFSD6 major facilitator superfamily domain containing 6 2 2
MIRT659880 CAPRIN1 cell cycle associated protein 1 2 2
MIRT660526 ARL4C ADP ribosylation factor like GTPase 4C 2 2
MIRT666286 SLC30A3 solute carrier family 30 member 3 2 2
MIRT686808 SNX2 sorting nexin 2 2 4
MIRT695302 TK1 thymidine kinase 1 2 2
MIRT699737 SERINC3 serine incorporator 3 2 2
MIRT700794 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT712270 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT712617 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT714264 RPL10A ribosomal protein L10a 2 2
MIRT715072 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715386 TADA3 transcriptional adaptor 3 2 2
MIRT716397 NPAS1 neuronal PAS domain protein 1 2 2
MIRT725328 NFASC neurofascin 2 2
MIRT725503 GANAB glucosidase II alpha subunit 2 2
MIRT732913 IRAK2 interleukin 1 receptor associated kinase 2 3 0
MIRT734890 SMAD3 SMAD family member 3 3 0
MIRT737328 LINC02476 long intergenic non-protein coding RNA 2476 3 0
MIRT737544 MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 4 0
MIRT755545 PAK1 p21 (RAC1) activated kinase 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-497 Bufalin NULL 9547215 Quantitative real-time PCR colorectal cancer HCT116 cells 24375248 2014 up-regulated
miR-497 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-497 Ethanol NULL 702 Quantitative real-time PCR CIE10 22141737 2012 up-regulated
miR-497 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
miR-497 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7, T47D)
hsa-mir-497 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-497 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-497 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-497-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-miR-497-3p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549, PC-9)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-497-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant tissue
hsa-miR-497-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

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