miRTarBase - #MIRT443190


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pre-miRNA Information
pre-miRNA hsa-mir-6733   
Genomic Coordinates chr1: 43171652 - 43171712
Description Homo sapiens miR-6733 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6733-5p
Sequence 6| UGGGAAAGACAAACUCAGAGUU |27
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs953882106 3 dbSNP
rs371499741 9 dbSNP
rs778441909 21 dbSNP
rs1348902205 22 dbSNP
Putative Targets

Gene Information
Gene Symbol PDHA1   
Synonyms PDHA, PDHAD, PDHCE1A, PHE1A
Description pyruvate dehydrogenase E1 alpha 1 subunit
Transcript NM_000284   
Other Transcripts NM_001173454 , NM_001173455 , NM_001173456   
Expression
Putative miRNA Targets on PDHA1
3'UTR of PDHA1
(miRNA target sites are highlighted)		 
>PDHA1|NM_000284|3'UTR
   1 GGGGAGGAGAAGGAGAGGTTATACCTTCAGGGGGCTACCAGACAGTGTTCTCAACTTGGTTAAGGAGGAAGAAAACCCAG
  81 TCAATGAAATTCAATGAAATTCTTGGAAACTTCCATTAAGTGTGTAGATTGAGCAGGTAGTAATTGCATGCAGTTTGTAC
 161 ATTAGTGCATTAAAAGATGAATTATTGAGTGCTTAAAGATTATTTTTGACTTAAAATAGTATACTTTGAACAAATACTCT
 241 AATTATGAAAAGGAAGAACAATTCCTTGTATGCCTGTTTCCCCTGCCCCCAGCCACCTTTTTGGGAGGAGACCATTATGG
 321 CGGGGCCCCTCACAGCATTCTACCAACCATAGCACCCACCCCGAGCAGCGCTGGTGCTGCAGCCTGTTCGCGCTGACCAT
 401 TTCTCTACAAGATACAATATTTATTATCAGGCAAGAGGACAGTTCCATTTTAAAATAAGACTTTTGTAATCATTCCAATT
 481 TTGTAATCATTTCAAAGGCCACATAACTTAGTTTTCTCTACTTACACATTCAGTATAAATATGAAGCTATTTTCTGTTCA
 561 TATCAAACATTAACTACAAGGCACATTCGTATCAGTTTTGTGTTTCTCAAATTGAAGTACCATACCAGTTCTGAGGCAGT
 641 GTCCCAGCTTCCATGTTTGTTAAATACCCCTTGTTTGTTTCACCATTCCAGCAAGTGCTGAAGGGTGTACTTTTTTTGAG
 721 ACAGGGTCGGGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCATGGCTCACTGCAGCCTCCACACCTCCTGGGCTC
 801 AAGCAATCCTCCCACCTCAGCCTCCTGCATAGCTGGGACTACAAGTGAATTTCCTAATATTCCGGGAGGTCAAAACCAAG
 881 GCTCACTGTTTTCACAATACACACAGTTCTATGTTTATAAATAACAGGTTTCAAAAGAAACTCAGGACAGTATTTAAAAC
 961 AAGTTCTTAAACTATTAATTGAACAATGGCATTTTTAAATATGTAAACACAGCGGAATTCGTGTATACACTAACAGAAGC
1041 TTTAACAAAACATGTAGCGTGGTGGGACACTCTGCCACAGCTTAGCTGATTGGTATCAAGCCTTGTCTTTGGTTTCTGAG
1121 GCCTCCTGAGCCCTTCTGTACTGGGAGACCGCACTCCAGAGTCTGCAGAGGAGACCACCCCTGGGAAACAAACACAGCTG
1201 TCTTCAGAGTCAGTGCTTCAAGCCAACAGAGCTTAAAACTGCAGTCCCTAATTTAAAAACCTAATGAAAATAAAAACATT
1281 CTCCTCACATATGGAGGTGACGCTCGTGTCCCAGCAGTAGTAGGACATGGCCTTAGAGGTACGTACCTGCAGAGAGCTGG
1361 CTATTTCAAATGACTCGGGAACAAGAAGGCAGGCTGCAGTTTAAAGAAGGGGGTGGGTCCAGCGTGCAGGCACGCTTGCC
1441 ATGTGCCTCCACCCACTCCCAGCCAGGCATTAATGGCAGGAGATTGGCCAGCTCTTCTCTGTCACATTCCTATTTCTGAC
1521 TTCTGCCTGGCTTTCAGTTTCTGCCCCACCTTGGCTTTTTCCCAGCTTGAACCTAATAGAACTCCAGAGTTTGGGGGGAG
1601 GCCCAGCCCTTTGTTTTCTGCTCTTGAAGCATATTCACACATAAAAAGTTGTATTCTCTTATACAAACTGTTTTGAGGCT
1681 CTTACCGTAGTCGAAGGTATCTTAGATCTTCCTTAGTGATCTCATTAAGAATATCCGAAAGTGTATAACCCTCTTCAACA
1761 ATCTGAAACAAAGATCAGATCCTTAAGAGCTGAGCAGCTGTGTAACAACAGCATAAGAATTTCTTTGTTGTAAATTTACC
1841 TTTTCAATTGTCTTTGCATCAGCTCCTTGCAGCCGCAACCAGTCTATAAGCTCTTTATCTGTTCTCTGCCCGTAGGGGCC
1921 TGCTGGGTTCTCTGTAATACCTGTAACGATTGGCAATTTGTTATATATTAGTCTAACCATAAAACTCTTCAAAAGTAACC
2001 AGTTGGATTAATAAATGATTCCAGAATGTAAATGTGATGTGAAAAAGAGATGAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGAGAC----UCAAAC--AGAAAGGGu 5'
            :||||    |  |||  |:|||||| 
Target 5' gtTTCTGCCCCACCTTGGCTTTTTCCCa 3'
 1537 - 1564 140.00 -14.60
2 
miRNA  3' uuGAGACUCAA-----ACAGAAAGggu 5'
            :||||| ||     || |||||   
Target 5' atTTCTGACTTCTGCCTGGCTTTCagt 3'
 1512 - 1538 124.00 -8.12
3 
miRNA  3' uugAGACUC-AAACAGAAAGGGu 5'
             | | || ||||| ||||:| 
Target 5' tcgTATCAGTTTTGTGTTTCTCa 3'
 587 - 609 123.00 -11.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
422931 8 ClinVar
10891 79 ClinVar
912975 111 ClinVar
913336 199 ClinVar
913337 320 ClinVar
913338 322 ClinVar
913339 323 ClinVar
913340 350 ClinVar
913341 393 ClinVar
913342 433 ClinVar
913343 526 ClinVar
914458 550 ClinVar
914459 576 ClinVar
914460 615 ClinVar
914461 708 ClinVar
914462 729 ClinVar
914463 730 ClinVar
914464 845 ClinVar
914465 858 ClinVar
914970 865 ClinVar
914971 1014 ClinVar
914972 1060 ClinVar
445325 1192 ClinVar
914973 1209 ClinVar
914974 1298 ClinVar
914975 1307 ClinVar
914976 1346 ClinVar
914977 1348 ClinVar
913014 1377 ClinVar
913015 1378 ClinVar
913016 1395 ClinVar
913017 1451 ClinVar
913018 1459 ClinVar
913019 1564 ClinVar
913020 1599 ClinVar
913021 1625 ClinVar
913384 1683 ClinVar
913385 1780 ClinVar
376916 1870 ClinVar
913386 1927 ClinVar
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs757713583 4 dbSNP
rs1229033836 7 dbSNP
rs1064796103 8 dbSNP
rs752082232 8 dbSNP
rs939163702 8 dbSNP
rs778420248 11 dbSNP
rs745596782 12 dbSNP
rs771447698 13 dbSNP
rs200547574 16 dbSNP
rs1296385542 17 dbSNP
rs373318863 17 dbSNP
rs1379058146 19 dbSNP
rs781632629 20 dbSNP
rs768539902 21 dbSNP
rs762321006 22 dbSNP
rs1338360605 23 dbSNP
rs1204191893 25 dbSNP
rs1249101511 28 dbSNP
rs1314619892 34 dbSNP
rs1031639189 35 dbSNP
rs776552491 35 dbSNP
rs1182226335 37 dbSNP
rs1423910567 39 dbSNP
rs111666443 40 dbSNP
rs1160380531 44 dbSNP
rs913963221 45 dbSNP
rs967185248 46 dbSNP
rs769687352 48 dbSNP
rs750727352 49 dbSNP
rs1360258394 51 dbSNP
rs756298361 57 dbSNP
rs1306592509 60 dbSNP
rs774406317 62 dbSNP
rs1169369237 64 dbSNP
rs759852734 65 dbSNP
rs1372604679 68 dbSNP
rs1368185328 69 dbSNP
rs780261890 69 dbSNP
rs1274312161 73 dbSNP
rs767657538 78 dbSNP
rs753648108 81 dbSNP
rs11554112 83 dbSNP
rs1328110471 84 dbSNP
rs1365656526 84 dbSNP
rs1424818027 87 dbSNP
rs979548726 87 dbSNP
rs925441836 88 dbSNP
rs1255919219 90 dbSNP
rs147338122 91 dbSNP
rs606231192 91 dbSNP
rs1258895673 94 dbSNP
rs778549806 95 dbSNP
rs748689790 96 dbSNP
rs1348530445 97 dbSNP
rs1233840026 100 dbSNP
rs757688624 101 dbSNP
rs1339740210 104 dbSNP
rs1310351337 106 dbSNP
rs1392866750 108 dbSNP
rs1491364217 109 dbSNP
rs771171560 110 dbSNP
rs709610 111 dbSNP
rs182754597 114 dbSNP
rs1204846207 115 dbSNP
rs779812493 117 dbSNP
rs746696047 118 dbSNP
rs1192444390 122 dbSNP
rs779602555 123 dbSNP
rs1449429211 124 dbSNP
rs745608853 127 dbSNP
rs746449195 128 dbSNP
rs1242201562 130 dbSNP
rs1430632221 130 dbSNP
rs1274709570 131 dbSNP
rs768167537 132 dbSNP
rs1468627460 135 dbSNP
rs187360934 135 dbSNP
rs781094210 137 dbSNP
rs1239056915 138 dbSNP
rs1197527702 140 dbSNP
rs1456568201 141 dbSNP
rs748123688 141 dbSNP
rs1235829477 142 dbSNP
rs1481906952 143 dbSNP
rs781670523 145 dbSNP
rs1178221029 148 dbSNP
rs1275136315 149 dbSNP
rs1392198162 153 dbSNP
rs1460910334 155 dbSNP
rs1328924898 157 dbSNP
rs1210472421 158 dbSNP
rs1355812752 158 dbSNP
rs1355585698 161 dbSNP
rs886805666 167 dbSNP
rs1439430142 168 dbSNP
rs1297197151 176 dbSNP
rs1049932095 178 dbSNP
rs1336126046 180 dbSNP
rs1308150382 182 dbSNP
rs1355712112 182 dbSNP
rs1444137261 186 dbSNP
rs1235447091 192 dbSNP
rs1291891723 193 dbSNP
rs1326033342 195 dbSNP
rs1003909173 199 dbSNP
rs1161943811 199 dbSNP
rs1455731340 204 dbSNP
rs1009456388 207 dbSNP
rs1158350330 212 dbSNP
rs1438100339 213 dbSNP
rs1275762539 214 dbSNP
rs1436107111 215 dbSNP
rs1199737285 217 dbSNP
rs1451081625 220 dbSNP
rs1206807976 222 dbSNP
rs1265268200 222 dbSNP
rs1354253952 231 dbSNP
rs1019221074 232 dbSNP
rs566285470 234 dbSNP
rs748590147 235 dbSNP
rs1258410600 236 dbSNP
rs1009574739 237 dbSNP
rs1486817144 237 dbSNP
rs1189787497 238 dbSNP
rs1319654925 240 dbSNP
rs1384426074 249 dbSNP
rs1415464144 271 dbSNP
rs1361690875 275 dbSNP
rs1297996550 277 dbSNP
rs1397163714 286 dbSNP
rs1418233062 286 dbSNP
rs1038121391 287 dbSNP
rs200632554 289 dbSNP
rs376636279 289 dbSNP
rs1168382869 290 dbSNP
rs1421592481 291 dbSNP
rs868405191 292 dbSNP
rs1195331424 294 dbSNP
rs1488592109 295 dbSNP
rs865978526 296 dbSNP
rs968438590 298 dbSNP
rs1278972514 301 dbSNP
rs773249692 302 dbSNP
rs1218294288 315 dbSNP
rs1042449 320 dbSNP
rs886566327 322 dbSNP
rs1042450 323 dbSNP
rs774381598 327 dbSNP
rs759806053 331 dbSNP
rs763789986 333 dbSNP
rs1341737476 334 dbSNP
rs1278093354 335 dbSNP
rs1398614661 343 dbSNP
rs1013526559 350 dbSNP
rs1335203114 356 dbSNP
rs960582479 360 dbSNP
rs1021366858 363 dbSNP
rs372658162 364 dbSNP
rs375225163 368 dbSNP
rs1431961300 370 dbSNP
rs753720613 371 dbSNP
rs939977898 375 dbSNP
rs1476097675 376 dbSNP
rs1237845935 381 dbSNP
rs1209117297 388 dbSNP
rs1440358763 389 dbSNP
rs867033377 390 dbSNP
rs761629687 391 dbSNP
rs765304960 392 dbSNP
rs56318063 393 dbSNP
rs144356124 398 dbSNP
rs1447691974 399 dbSNP
rs72116174 399 dbSNP
rs1338975764 400 dbSNP
rs199685000 401 dbSNP
rs1333580882 403 dbSNP
rs764801500 410 dbSNP
rs1441581609 411 dbSNP
rs779722514 412 dbSNP
rs1243704782 415 dbSNP
rs1471672735 415 dbSNP
rs933553910 416 dbSNP
rs1234324156 417 dbSNP
rs919633508 418 dbSNP
rs973955019 418 dbSNP
rs1235832167 420 dbSNP
rs1214967488 423 dbSNP
rs369332453 427 dbSNP
rs983752668 429 dbSNP
rs754719295 433 dbSNP
rs932293745 442 dbSNP
rs1376390204 449 dbSNP
rs201758797 449 dbSNP
rs375651955 449 dbSNP
rs960272070 453 dbSNP
rs1438677426 455 dbSNP
rs1014525507 462 dbSNP
rs1350440771 462 dbSNP
rs372190247 462 dbSNP
rs939689528 465 dbSNP
rs944864127 466 dbSNP
rs183744566 467 dbSNP
rs1320767245 468 dbSNP
rs1325189806 476 dbSNP
rs1235922359 477 dbSNP
rs1195005374 479 dbSNP
rs1229165470 479 dbSNP
rs1430710716 480 dbSNP
rs892637509 485 dbSNP
rs898263736 486 dbSNP
rs1450329853 494 dbSNP
rs937821249 498 dbSNP
rs1055346465 500 dbSNP
rs1288643550 501 dbSNP
rs1241268443 503 dbSNP
rs763688379 505 dbSNP
rs1307311866 506 dbSNP
rs1279806575 507 dbSNP
rs113050549 508 dbSNP
rs1292958485 511 dbSNP
rs770179781 511 dbSNP
rs903870951 512 dbSNP
rs1351672487 519 dbSNP
rs778207227 526 dbSNP
rs749812407 532 dbSNP
rs1378136436 533 dbSNP
rs1177786030 535 dbSNP
rs1433325252 544 dbSNP
rs1286155631 545 dbSNP
rs770933958 548 dbSNP
rs1423870356 549 dbSNP
rs187525386 550 dbSNP
rs1253573361 553 dbSNP
rs1455150856 555 dbSNP
rs1477339971 560 dbSNP
rs746061580 564 dbSNP
rs1204874594 569 dbSNP
rs1217860599 571 dbSNP
rs191995452 576 dbSNP
rs1284218705 577 dbSNP
rs1212533163 584 dbSNP
rs1376712224 585 dbSNP
rs1312926931 589 dbSNP
rs776254250 590 dbSNP
rs1160638767 592 dbSNP
rs1278723390 594 dbSNP
rs1399237040 599 dbSNP
rs1304311874 601 dbSNP
rs1383313844 601 dbSNP
rs1466234333 601 dbSNP
rs1457075540 607 dbSNP
rs1173405849 611 dbSNP
rs1478499418 613 dbSNP
rs1426496496 614 dbSNP
rs5955761 615 dbSNP
rs537446476 622 dbSNP
rs1257511832 634 dbSNP
rs964773512 637 dbSNP
rs1438714650 651 dbSNP
rs1483712288 651 dbSNP
rs1208154799 654 dbSNP
rs1255603426 654 dbSNP
rs974885468 655 dbSNP
rs1013620229 659 dbSNP
rs1217950108 661 dbSNP
rs1336564298 664 dbSNP
rs1338246535 664 dbSNP
rs1015416771 671 dbSNP
rs1378044994 672 dbSNP
rs1281040569 675 dbSNP
rs1300711497 690 dbSNP
rs1466786497 702 dbSNP
rs1030907395 707 dbSNP
rs150945967 708 dbSNP
rs1465592646 710 dbSNP
rs1207893681 719 dbSNP
rs1167408463 725 dbSNP
rs961184480 725 dbSNP
rs773225586 726 dbSNP
rs1042452 729 dbSNP
rs376808450 730 dbSNP
rs1266121114 733 dbSNP
rs1181960425 743 dbSNP
rs1459212837 755 dbSNP
rs1238871753 766 dbSNP
rs1198042840 778 dbSNP
rs751130904 788 dbSNP
rs1438020111 791 dbSNP
rs1267112593 792 dbSNP
rs1245328091 797 dbSNP
rs973986297 807 dbSNP
rs939659696 819 dbSNP
rs1183490981 828 dbSNP
rs1361729930 832 dbSNP
rs1320876072 835 dbSNP
rs754555154 839 dbSNP
rs1042453 845 dbSNP
rs1166103538 848 dbSNP
rs182836908 858 dbSNP
rs919616845 862 dbSNP
rs187083263 864 dbSNP
rs192450087 865 dbSNP
rs1395014284 866 dbSNP
rs1054922662 871 dbSNP
rs896270307 872 dbSNP
rs949256948 873 dbSNP
rs1451216236 898 dbSNP
rs1161984509 904 dbSNP
rs767199793 905 dbSNP
rs1042669783 906 dbSNP
rs749787977 912 dbSNP
rs1327033288 918 dbSNP
rs1178151551 919 dbSNP
rs760736313 919 dbSNP
rs1227552333 922 dbSNP
rs757815346 923 dbSNP
rs542108895 924 dbSNP
rs1488080651 929 dbSNP
rs1289365730 933 dbSNP
rs778832973 938 dbSNP
rs184532061 939 dbSNP
rs1241992456 940 dbSNP
rs985497278 944 dbSNP
rs1354036653 949 dbSNP
rs1308033219 950 dbSNP
rs1336831895 951 dbSNP
rs1231424477 956 dbSNP
rs772075136 957 dbSNP
rs374396566 961 dbSNP
rs775731731 961 dbSNP
rs1264828970 978 dbSNP
rs1323575118 986 dbSNP
rs902452095 988 dbSNP
rs1000809999 989 dbSNP
rs1480646947 990 dbSNP
rs1301703645 996 dbSNP
rs1421874522 998 dbSNP
rs1197047678 1007 dbSNP
rs1361487756 1009 dbSNP
rs1158262400 1010 dbSNP
rs1468746744 1012 dbSNP
rs912317775 1012 dbSNP
rs1042456 1014 dbSNP
rs769643820 1015 dbSNP
rs900536893 1018 dbSNP
rs140383712 1022 dbSNP
rs1474494370 1024 dbSNP
rs1164641361 1028 dbSNP
rs781582453 1029 dbSNP
rs1030416947 1031 dbSNP
rs1231827009 1032 dbSNP
rs776627726 1032 dbSNP
rs955006842 1037 dbSNP
rs1005064401 1043 dbSNP
rs1371599788 1050 dbSNP
rs1434339863 1053 dbSNP
rs773012317 1054 dbSNP
rs1344127743 1055 dbSNP
rs762963142 1056 dbSNP
rs1288636445 1059 dbSNP
rs15816 1060 dbSNP
rs760828301 1062 dbSNP
rs945503431 1063 dbSNP
rs1465285550 1067 dbSNP
rs1195731122 1068 dbSNP
rs762592504 1070 dbSNP
rs754361374 1071 dbSNP
rs762427939 1075 dbSNP
rs1187290256 1081 dbSNP
rs765681576 1086 dbSNP
rs1190707899 1087 dbSNP
rs748635462 1087 dbSNP
rs1278863609 1092 dbSNP
rs775059849 1102 dbSNP
rs750757959 1103 dbSNP
rs1199427438 1106 dbSNP
rs758692867 1106 dbSNP
rs762409221 1108 dbSNP
rs963577934 1112 dbSNP
rs1407334158 1116 dbSNP
rs1165543621 1118 dbSNP
rs779698506 1119 dbSNP
rs1434269786 1120 dbSNP
rs904066679 1121 dbSNP
rs140145114 1130 dbSNP
rs1298642306 1131 dbSNP
rs145675672 1133 dbSNP
rs61744590 1134 dbSNP
rs756645339 1139 dbSNP
rs56021619 1142 dbSNP
rs778346850 1143 dbSNP
rs768004727 1144 dbSNP
rs747680098 1151 dbSNP
rs756039907 1152 dbSNP
rs147753175 1153 dbSNP
rs759041463 1155 dbSNP
rs766954168 1158 dbSNP
rs557102951 1160 dbSNP
rs1404016169 1162 dbSNP
rs750762941 1162 dbSNP
rs1270522443 1164 dbSNP
rs747270244 1167 dbSNP
rs761048720 1167 dbSNP
rs768831534 1172 dbSNP
rs1422770856 1173 dbSNP
rs1335155853 1174 dbSNP
rs1448110764 1176 dbSNP
rs1473637941 1178 dbSNP
rs776800732 1178 dbSNP
rs1236136610 1184 dbSNP
rs766536396 1186 dbSNP
rs1186419347 1187 dbSNP
rs761827915 1189 dbSNP
rs202102403 1192 dbSNP
rs1455654040 1197 dbSNP
rs755834416 1198 dbSNP
rs1198674515 1202 dbSNP
rs765707363 1205 dbSNP
rs1319275691 1206 dbSNP
rs1401261893 1206 dbSNP
rs369499936 1209 dbSNP
rs373390286 1210 dbSNP
rs770495684 1215 dbSNP
rs1213251837 1216 dbSNP
rs766795601 1222 dbSNP
rs1293458166 1228 dbSNP
rs751191482 1230 dbSNP
rs1225995420 1232 dbSNP
rs1055572934 1237 dbSNP
rs896481400 1245 dbSNP
rs923800219 1247 dbSNP
rs1380802600 1256 dbSNP
rs1333471005 1262 dbSNP
rs936565582 1266 dbSNP
rs1353899650 1267 dbSNP
rs1326762125 1272 dbSNP
rs1053740754 1287 dbSNP
rs1414264580 1293 dbSNP
rs796246045 1295 dbSNP
rs778678656 1298 dbSNP
rs996197748 1302 dbSNP
rs995720508 1303 dbSNP
rs1026911872 1304 dbSNP
rs754247336 1306 dbSNP
rs745566169 1307 dbSNP
rs1291071314 1312 dbSNP
rs189054591 1312 dbSNP
rs1005400592 1313 dbSNP
rs1175710770 1327 dbSNP
rs985392445 1344 dbSNP
rs193253848 1346 dbSNP
rs1241045421 1348 dbSNP
rs1372717490 1350 dbSNP
rs912249698 1351 dbSNP
rs1438565162 1357 dbSNP
rs1350351322 1369 dbSNP
rs963546680 1377 dbSNP
rs56039350 1378 dbSNP
rs965023500 1379 dbSNP
rs988577178 1383 dbSNP
rs1034574417 1386 dbSNP
rs55856360 1395 dbSNP
rs1363777790 1397 dbSNP
rs1192385403 1398 dbSNP
rs990519199 1399 dbSNP
rs1247776139 1400 dbSNP
rs1044241597 1410 dbSNP
rs1489960363 1411 dbSNP
rs917600173 1417 dbSNP
rs970492070 1422 dbSNP
rs925469441 1424 dbSNP
rs760525544 1425 dbSNP
rs779999826 1434 dbSNP
rs768422526 1435 dbSNP
rs996125838 1437 dbSNP
rs1203864269 1444 dbSNP
rs1368271274 1445 dbSNP
rs747229060 1451 dbSNP
rs1247980566 1455 dbSNP
rs923765752 1459 dbSNP
rs1342153036 1461 dbSNP
rs1298509411 1465 dbSNP
rs769050360 1468 dbSNP
rs1013518852 1477 dbSNP
rs1177666327 1486 dbSNP
rs1414511000 1492 dbSNP
rs1430695116 1500 dbSNP
rs1199313702 1511 dbSNP
rs1393492641 1514 dbSNP
rs1432877041 1528 dbSNP
rs1194782124 1529 dbSNP
rs777682163 1529 dbSNP
rs1053666674 1538 dbSNP
rs1259156243 1544 dbSNP
rs1212420126 1552 dbSNP
rs1037093465 1561 dbSNP
rs7883708 1564 dbSNP
rs1221611500 1566 dbSNP
rs931952235 1570 dbSNP
rs770658441 1571 dbSNP
rs1381416696 1576 dbSNP
rs995354840 1580 dbSNP
rs5955550 1586 dbSNP
rs940776922 1592 dbSNP
rs1036409244 1595 dbSNP
rs11094770 1599 dbSNP
rs771609750 1602 dbSNP
rs762905278 1603 dbSNP
rs1218320598 1614 dbSNP
rs1307306314 1615 dbSNP
rs889620474 1616 dbSNP
rs1319058829 1622 dbSNP
rs1171613134 1640 dbSNP
rs1289721589 1644 dbSNP
rs201259816 1648 dbSNP
rs376593530 1649 dbSNP
rs1482548800 1657 dbSNP
rs760296050 1658 dbSNP
rs755594888 1661 dbSNP
rs370565981 1663 dbSNP
rs869305616 1665 dbSNP
rs1212056929 1667 dbSNP
rs1242639335 1671 dbSNP
rs1201796838 1676 dbSNP
rs749254470 1679 dbSNP
rs55744630 1683 dbSNP
rs1184403880 1684 dbSNP
rs377382652 1686 dbSNP
rs753516995 1687 dbSNP
rs748198804 1688 dbSNP
rs762188631 1689 dbSNP
rs148399187 1694 dbSNP
rs1448313019 1697 dbSNP
rs763409232 1698 dbSNP
rs1369520749 1699 dbSNP
rs977795204 1702 dbSNP
rs142533585 1705 dbSNP
rs1371710222 1707 dbSNP
rs766893716 1712 dbSNP
rs1335899217 1716 dbSNP
rs774659644 1717 dbSNP
rs150957359 1718 dbSNP
rs370651623 1719 dbSNP
rs1347776986 1725 dbSNP
rs750874490 1736 dbSNP
rs140779387 1737 dbSNP
rs1274425240 1738 dbSNP
rs752352625 1739 dbSNP
rs1207639901 1742 dbSNP
rs371285733 1743 dbSNP
rs144734730 1751 dbSNP
rs1410645400 1752 dbSNP
rs751563348 1752 dbSNP
rs1195170721 1758 dbSNP
rs763556279 1759 dbSNP
rs780260798 1764 dbSNP
rs1222925505 1774 dbSNP
rs1358338797 1777 dbSNP
rs373779094 1778 dbSNP
rs779022123 1779 dbSNP
rs758279534 1780 dbSNP
rs938175895 1787 dbSNP
rs1174006459 1790 dbSNP
rs781550393 1793 dbSNP
rs1427418874 1794 dbSNP
rs374494282 1796 dbSNP
rs1295700862 1800 dbSNP
rs1396779538 1803 dbSNP
rs869147130 1804 dbSNP
rs769886359 1810 dbSNP
rs777666685 1813 dbSNP
rs755016325 1814 dbSNP
rs749418204 1815 dbSNP
rs771363028 1816 dbSNP
rs1297308957 1817 dbSNP
rs757189654 1820 dbSNP
rs1364463236 1831 dbSNP
rs1181115842 1838 dbSNP
rs781517592 1841 dbSNP
rs989329615 1842 dbSNP
rs1252052240 1843 dbSNP
rs759883184 1848 dbSNP
rs1269336518 1849 dbSNP
rs772494786 1859 dbSNP
rs1269620396 1863 dbSNP
rs1199963490 1864 dbSNP
rs1490120645 1867 dbSNP
rs15943 1870 dbSNP
rs1194257410 1874 dbSNP
rs760297711 1875 dbSNP
rs763826263 1876 dbSNP
rs1172293694 1879 dbSNP
rs1350886167 1894 dbSNP
rs753243729 1896 dbSNP
rs761409953 1900 dbSNP
rs770697702 1909 dbSNP
rs368526609 1912 dbSNP
rs372102191 1913 dbSNP
rs140380348 1917 dbSNP
rs752937000 1925 dbSNP
rs778062708 1927 dbSNP
rs749306111 1931 dbSNP
rs1296783815 1935 dbSNP
rs1385917519 1939 dbSNP
rs1340071069 1944 dbSNP
rs1242955832 1945 dbSNP
rs771054574 1948 dbSNP
rs781136595 1948 dbSNP
rs779385101 1949 dbSNP
rs756514533 1951 dbSNP
rs1055877510 1952 dbSNP
rs746410710 1954 dbSNP
rs1379356189 1955 dbSNP
rs1268001704 1958 dbSNP
rs778642797 1960 dbSNP
rs745681893 1964 dbSNP
rs1200074727 1965 dbSNP
rs1463513229 1966 dbSNP
rs1480029163 1967 dbSNP
rs375095104 1972 dbSNP
rs368185128 1983 dbSNP
rs755908979 1985 dbSNP
rs1185047575 1988 dbSNP
rs745807211 1989 dbSNP
rs776362774 1993 dbSNP
rs1024982339 1998 dbSNP
rs1375083448 2006 dbSNP
rs1226942527 2011 dbSNP
rs181554208 2020 dbSNP
rs1202924209 2021 dbSNP
rs774947730 2037 dbSNP
rs1288179542 2042 dbSNP
rs1336076595 2052 dbSNP
rs906163697 2053 dbSNP
rs1235715428 2063 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uugagacucaAAC--AGAAAGGGu 5'
                    |||  |:|||||| 
Target 5' ----------UUGGCUUUUUCCCa 3'
 		1 - 14
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000379806.5 | 3UTR | UUGGCUUUUUCCCAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
161 hsa-miR-6733-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT075325 SF3B3 splicing factor 3b subunit 3 2 4
MIRT082764 EPN1 epsin 1 2 4
MIRT119868 NRBP1 nuclear receptor binding protein 1 2 2
MIRT124577 PRRC2B proline rich coiled-coil 2B 2 2
MIRT126718 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT128925 KMT2A lysine methyltransferase 2A 2 2
MIRT135191 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 2
MIRT145630 LASP1 LIM and SH3 protein 1 2 2
MIRT175518 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT188406 ATXN7L3B ataxin 7 like 3B 2 2
MIRT192486 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT208383 SLC25A36 solute carrier family 25 member 36 2 2
MIRT216690 F2R coagulation factor II thrombin receptor 2 2
MIRT235839 FAM217B family with sequence similarity 217 member B 2 2
MIRT257000 RGMB repulsive guidance molecule family member b 2 2
MIRT266594 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT273614 SP1 Sp1 transcription factor 2 2
MIRT276567 AKAP11 A-kinase anchoring protein 11 2 2
MIRT285544 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT291540 LRRC8B leucine rich repeat containing 8 VRAC subunit B 2 2
MIRT317159 E2F3 E2F transcription factor 3 2 4
MIRT340688 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT366934 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 2
MIRT376193 AP1M1 adaptor related protein complex 1 mu 1 subunit 2 2
MIRT441983 TSTD2 thiosulfate sulfurtransferase like domain containing 2 2 2
MIRT442059 POU3F2 POU class 3 homeobox 2 2 6
MIRT443190 PDHA1 pyruvate dehydrogenase E1 alpha 1 subunit 2 2
MIRT445133 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT445881 WBP1L WW domain binding protein 1 like 2 2
MIRT449359 DPP6 dipeptidyl peptidase like 6 2 2
MIRT451399 FARSA phenylalanyl-tRNA synthetase alpha subunit 2 2
MIRT451802 CDCA3 cell division cycle associated 3 2 4
MIRT452295 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT452494 HMGXB3 HMG-box containing 3 2 2
MIRT453354 ZNF3 zinc finger protein 3 2 2
MIRT453375 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 2 2
MIRT453719 RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 2 2
MIRT453839 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454009 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT454371 PIGS phosphatidylinositol glycan anchor biosynthesis class S 2 2
MIRT454729 ARSK arylsulfatase family member K 2 2
MIRT455227 KIAA2013 KIAA2013 2 2
MIRT455866 SLC35C2 solute carrier family 35 member C2 2 2
MIRT456386 KLHL12 kelch like family member 12 2 2
MIRT457017 ACADSB acyl-CoA dehydrogenase, short/branched chain 2 2
MIRT457048 NEGR1 neuronal growth regulator 1 2 2
MIRT457402 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT457808 KLHL25 kelch like family member 25 2 2
MIRT458361 C3orf80 chromosome 3 open reading frame 80 2 2
MIRT458678 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT459629 GABARAP GABA type A receptor-associated protein 2 2
MIRT460955 MUL1 mitochondrial E3 ubiquitin protein ligase 1 2 2
MIRT462241 PRSS16 protease, serine 16 2 2
MIRT462472 FIZ1 FLT3 interacting zinc finger 1 2 2
MIRT462572 STS steroid sulfatase 2 2
MIRT462931 ZNF827 zinc finger protein 827 2 2
MIRT463442 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464129 VPS35 VPS35, retromer complex component 2 2
MIRT464688 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465653 TNPO2 transportin 2 2 2
MIRT465951 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466032 TMEM189 transmembrane protein 189 2 2
MIRT466577 TBC1D2B TBC1 domain family member 2B 2 2
MIRT467506 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 2
MIRT467786 SLC2A14 solute carrier family 2 member 14 2 2
MIRT468104 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT468292 SFT2D2 SFT2 domain containing 2 2 2
MIRT469004 RNF41 ring finger protein 41 2 2
MIRT469753 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT473205 MINK1 misshapen like kinase 1 2 4
MIRT473314 MEX3A mex-3 RNA binding family member A 2 2
MIRT473549 MAVS mitochondrial antiviral signaling protein 2 2
MIRT474269 LATS2 large tumor suppressor kinase 2 2 2
MIRT475111 IPPK inositol-pentakisphosphate 2-kinase 2 2
MIRT475436 HYOU1 hypoxia up-regulated 1 2 2
MIRT475751 HDLBP high density lipoprotein binding protein 2 2
MIRT475972 GTPBP2 GTP binding protein 2 2 2
MIRT476480 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT476595 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT476684 FURIN furin, paired basic amino acid cleaving enzyme 2 2
MIRT477261 ERGIC2 ERGIC and golgi 2 2 2
MIRT477647 EFNA1 ephrin A1 2 2
MIRT477790 E2F2 E2F transcription factor 2 2 2
MIRT477871 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT478012 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT479558 CDC5L cell division cycle 5 like 2 4
MIRT480420 C17orf85 nuclear cap binding subunit 3 2 2
MIRT480642 BSCL2 BSCL2, seipin lipid droplet biogenesis associated 2 2
MIRT480778 BMP2 bone morphogenetic protein 2 2 2
MIRT481554 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT481689 AR androgen receptor 2 2
MIRT481836 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT483138 FOXC1 forkhead box C1 2 2
MIRT483919 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT484202 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484433 RAB7A RAB7A, member RAS oncogene family 2 4
MIRT485544 GP5 glycoprotein V platelet 2 2
MIRT486558 SLC38A4 solute carrier family 38 member 4 2 2
MIRT486727 MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 2 4
MIRT490490 GLRA3 glycine receptor alpha 3 2 2
MIRT490682 SSTR1 somatostatin receptor 1 2 2
MIRT490792 PSMD3 proteasome 26S subunit, non-ATPase 3 2 2
MIRT491060 ACVR1B activin A receptor type 1B 2 4
MIRT492614 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT492768 PDGFB platelet derived growth factor subunit B 2 2
MIRT493988 EHD1 EH domain containing 1 2 2
MIRT494510 BDNF-AS BDNF antisense RNA 2 2
MIRT494755 AP3M2 adaptor related protein complex 3 mu 2 subunit 2 2
MIRT499802 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT501336 RNF44 ring finger protein 44 2 4
MIRT509490 CENPA centromere protein A 2 2
MIRT509643 ZNF354B zinc finger protein 354B 2 10
MIRT510147 PDGFRA platelet derived growth factor receptor alpha 2 4
MIRT510567 UNG uracil DNA glycosylase 2 6
MIRT525087 FRK fyn related Src family tyrosine kinase 2 2
MIRT528452 NXT2 nuclear transport factor 2 like export factor 2 2 4
MIRT531970 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT532084 RTTN rotatin 2 2
MIRT532756 LDHD lactate dehydrogenase D 2 2
MIRT535072 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT535637 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT545410 EIF4A3 eukaryotic translation initiation factor 4A3 2 4
MIRT545911 ZFP91 ZFP91 zinc finger protein 2 4
MIRT548007 GRB2 growth factor receptor bound protein 2 2 4
MIRT548545 DR1 down-regulator of transcription 1 2 2
MIRT550075 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT553730 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT557569 GNPTAB N-acetylglucosamine-1-phosphate transferase alpha and beta subunits 2 2
MIRT558025 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558139 ENC1 ectodermal-neural cortex 1 2 2
MIRT560173 COA1 cytochrome c oxidase assembly factor 1 homolog 2 2
MIRT561700 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT565101 UBE3C ubiquitin protein ligase E3C 2 2
MIRT565739 SESN3 sestrin 3 2 2
MIRT566669 NACC2 NACC family member 2 2 2
MIRT567040 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT569627 ZNF746 zinc finger protein 746 2 2
MIRT570530 RPH3A rabphilin 3A 2 2
MIRT570939 CPE carboxypeptidase E 2 2
MIRT574774 FGF2 fibroblast growth factor 2 2 2
MIRT620120 LACC1 laccase domain containing 1 2 2
MIRT624338 CISD1 CDGSH iron sulfur domain 1 2 2
MIRT625434 RMDN1 regulator of microtubule dynamics 1 2 2
MIRT640528 TET3 tet methylcytosine dioxygenase 3 2 4
MIRT646916 TRIM14 tripartite motif containing 14 2 2
MIRT656298 METTL1 methyltransferase like 1 2 2
MIRT660192 BMPR1A bone morphogenetic protein receptor type 1A 2 2
MIRT661360 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT667769 KCTD11 potassium channel tetramerization domain containing 11 2 2
MIRT683187 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 2
MIRT685843 ANGEL1 angel homolog 1 2 2
MIRT688553 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT689424 CYB561 cytochrome b561 2 2
MIRT698505 TGFBR1 transforming growth factor beta receptor 1 2 2
MIRT701232 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT702506 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT706488 SEPT6 septin 6 2 2
MIRT713774 ZNF460 zinc finger protein 460 2 2
MIRT716991 ARL6IP4 ADP ribosylation factor like GTPase 6 interacting protein 4 2 2
MIRT722644 MPEG1 macrophage expressed 1 2 2
MIRT725254 PARVB parvin beta 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6733 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-6733 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-6733-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-6733-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-6733-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-6733-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)

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