miRTarBase - #MIRT443331


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pre-miRNA Information
pre-miRNA hsa-mir-4753   
Genomic Coordinates chr1: 235190034 - 235190116
Description Homo sapiens miR-4753 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4753-5p
Sequence 10| CAAGGCCAAAGGAAGAGAACAG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs547986869 3 dbSNP
rs1007787337 7 dbSNP
rs1224263160 12 dbSNP
rs1256249071 13 dbSNP
rs1484015538 14 dbSNP
rs535678819 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol OCRL   
Synonyms INPP5F, LOCR, NPHL2, OCRL-1, OCRL1
Description OCRL, inositol polyphosphate-5-phosphatase
Transcript NM_000276   
Other Transcripts NM_001587   
Expression
Putative miRNA Targets on OCRL
3'UTR of OCRL
(miRNA target sites are highlighted)		 
>OCRL|NM_000276|3'UTR
   1 GGCTTTTACTGTTCTCTGATATTCTAGAAGCAGACGATCTCGGGCTCCAAGTATTTCAGAATGATTTAAAAAGTCATGCC
  81 ACAGGAAGGGTCTATTGCAGAATTTCAAGTTCTGTTTATAGTAAAAAGGAAGAGCGTTTCCTAATCCCTCCTTTACCATA
 161 TCCTACACAGAAAAATACTTTTAGACTTATATTGCCAAGCCAAAGTTACCATATTTTGGTGTTTTTGTGTTTTCTCTTTA
 241 TAAGGCAAAAAGATCTGTATTTACACTCCTTCACCTAGGGATGTGTTTGTTGCCCTCCTACCCAATTGTCATGATTGTCC
 321 TTAGTACCCTAGGCCTAGATTCTGAGATCTTCCCATTCTAGGCCTACAAGCACTACTTGCTGTAGCTGAGACTTGTCTAG
 401 AGTCCTTTGTTTTGCACTTTTGACCCACCCCTTCCTGGATCACTCCTTTGCACTCCACTCCCCTCGTTCTGTCACTTTGA
 481 ACGAAGTCTGAGTGAGGCTAGTGACTCCTTGGGTGTCCTCAACAGTGAATTCACTGTCTGCGTGCAGTTATTACATGCAT
 561 TTGTGCATTTCTACTACAATGGCATCTTTATGTCTCTGTAACATTGGCCTTTTCATGGCTCCACACTGGGTGGAACCATA
 641 TTCTCTTAGATCACATTTAGTAGCATAACTGTAGGGACTATTAGAGATGGCATCTCATCGATGAGAGAGAATCACAATCA
 721 GAATGGAAGCACTTTGAGTATCTGAAGAGTGAGAGCATTCATGTTTGACAGGTCCTGCTTCCCACTATCCTTTTCCTGTT
 801 ATTATTCAAATTTTACACAAGGACTAATCCTGGGTGTCTCTGAGACCCATCTCCTGCCTAGACATCCACCTCCAGAGCAA
 881 CACTGGCCCCACAGTAAAAGAGGAAGTCTTGTACCTCAGGCAGGCCCATCTAGAGCTATTGCTCCTTCCCACAGCAAAGG
 961 TATTGTGGATGACCCTTAGAATCCATTCTCTGGTCTTCTGAAATACCAAGGGCAGATGTCACCTCCTTCCTCAGCAGGAC
1041 TGACTCTGGGCTCTACAACCAGCTCCTTCACATAAAGGGTTTAGAGACTCCCCTTGGCTCCCAGTCACCATATCCAGTGT
1121 TGTGTAAAGAGACTGGCCAACAGGACCAACCAAGCACCTTACCTCTCCCATACAAGATGACCCTCTGAGCTTTTCATTTA
1201 TTCAAGCTCTGTGGTACAGCCTTTTTTTAAAATAAATTAATCTATATTGGTTGACAAACAAGCCACCAACCACTGACTGC
1281 AAAACTGCCTGATGCAGTTGGGTTCCTCCTGGTTTTCTTTTGTTACAACCACCCTTGCCTGTTTACATTAATTGCAAGGA
1361 GCATAACGTACAGGCTGTATGTACAATCCTGGGCATTGACTCTGTGACATTTCTAGCATATCCAAGGCACCACCAGTGAT
1441 TTCTCCTGTTTCTTGGTGGGGGTGGGGGGGAAGGTACGTATTCTGCAATATGGCTAAACCCTTTCCTGATTGAGAGTTAA
1521 AGCAATAGGAGTCAAGTTACTGGTGCCACAGATCTGGAGGTATGATAGGTCAGGGGCTAGGTGTTGAACTTAGTTAATGG
1601 AAGACTGAGAGCAGAACAGGTTTGTCATCTCCGCAAGGCCAGAAAGTGATCACAAAAAGAGGCAGATGATAGACACTGGG
1681 GTAGGGTCATACCACAGGGAAATACCTTTCCTGGGCTTGTTTTCTAGCATATCACTGACCTGGGATCTTTGGGTGATCAA
1761 GGGTGTGGTTAGTGGAGGCTCTGTGCTGCACGTATGCAGTATCCTATCTCTTTCTACATCAGATCAAAACACTAAGTTGG
1841 TGTACTGCCTCGACCTTTTTTCAGCTCATCCTGGAACATATACAGAGTTGAGAGTTTTAGACAATCTCTAGGTAGAGGAG
1921 ACAAGATGTAGACCCAGACAGAAGAAATCTGCTTCCCTACCATGGCTATTCCAGCACCCCAACCTGTAATTGCCAAGTCC
2001 TCTAAGGTACTAATTTGTAGCTGCTCTGAAGTAAGGATTTCGGATTCAGCTGGTAGGGAAAGACTCTGCACCTGCTGTCT
2081 TAGGGAAGAAATGGTTCAAATCCATGTGGTGACATTGCATTAGTCTCCCTTTCACTGTTTTCTTATTCTGTAATTGTTTG
2161 TTATATTTCCCAAAAACGTCTTGATCACTAAGCAAAGCTGCTAGTGGGATTCTATATTTCGTGTCATCTTTTTTATTATA
2241 ATTTATTGCAAATTTTTTTCTGAATAAATATATGTTGTGTGAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaCA-AGAGAAGGAAACCGGAAc 5'
            || ||| |  | |||||||| 
Target 5' atGTCTCTGTAACATTGGCCTTt 3'
 590 - 612 160.00 -16.70
2 
miRNA  3' gacaAGAGAAGGAAACCGGAAc 5'
              || | |:|| |||:||| 
Target 5' agaaTC-CATTCTCTGGTCTTc 3'
 978 - 998 141.00 -10.50
3 
miRNA  3' gaCAAGAGAAGGA-AACCGGAAc 5'
            |||   |||||  |||::|| 
Target 5' caGTTGGGTTCCTCCTGGTTTTc 3'
 1295 - 1317 128.00 -11.70
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs371100360 12 dbSNP
rs750012566 12 dbSNP
rs1045795446 15 dbSNP
rs373689273 20 dbSNP
rs748470664 35 dbSNP
rs367870998 36 dbSNP
rs772015678 37 dbSNP
rs773327987 42 dbSNP
rs370737806 43 dbSNP
rs748811584 44 dbSNP
rs1421212799 46 dbSNP
rs1021450289 58 dbSNP
rs1238607697 69 dbSNP
rs892891123 75 dbSNP
rs1311721844 77 dbSNP
rs1439215089 78 dbSNP
rs1370667564 79 dbSNP
rs1327192717 82 dbSNP
rs1364687239 95 dbSNP
rs1382149667 96 dbSNP
rs754667025 110 dbSNP
rs1191323489 115 dbSNP
rs1436167122 115 dbSNP
rs1453605881 125 dbSNP
rs746317573 127 dbSNP
rs1195435414 131 dbSNP
rs772585775 137 dbSNP
rs1260953715 150 dbSNP
rs954248614 159 dbSNP
rs984390913 167 dbSNP
rs780526267 168 dbSNP
rs1232305896 182 dbSNP
rs140474314 191 dbSNP
rs1324258734 199 dbSNP
rs1205298651 209 dbSNP
rs963379942 215 dbSNP
rs1246034362 220 dbSNP
rs1015996772 223 dbSNP
rs5977114 225 dbSNP
rs1318225843 227 dbSNP
rs918997401 241 dbSNP
rs961337817 250 dbSNP
rs974086638 258 dbSNP
rs919966650 263 dbSNP
rs2071706 279 dbSNP
rs1395460646 285 dbSNP
rs773562825 302 dbSNP
rs768804911 318 dbSNP
rs1474295799 328 dbSNP
rs1372481383 346 dbSNP
rs1476773306 355 dbSNP
rs926478666 365 dbSNP
rs1193761483 370 dbSNP
rs776895785 378 dbSNP
rs15690 380 dbSNP
rs771423501 382 dbSNP
rs1265356873 396 dbSNP
rs776626479 400 dbSNP
rs1009981128 401 dbSNP
rs1209006444 406 dbSNP
rs1485507426 407 dbSNP
rs1042415908 418 dbSNP
rs1221346477 431 dbSNP
rs141362521 435 dbSNP
rs1270157330 448 dbSNP
rs1228727214 451 dbSNP
rs542130397 455 dbSNP
rs1341846014 461 dbSNP
rs1310467861 462 dbSNP
rs998283162 467 dbSNP
rs1375741433 471 dbSNP
rs1157381764 475 dbSNP
rs1388383678 483 dbSNP
rs1028471854 484 dbSNP
rs954194483 485 dbSNP
rs1401436686 490 dbSNP
rs1418469966 491 dbSNP
rs748907876 492 dbSNP
rs1168439444 499 dbSNP
rs1478725233 500 dbSNP
rs1415579497 518 dbSNP
rs1185976103 530 dbSNP
rs1320569564 533 dbSNP
rs1005771102 543 dbSNP
rs191912395 556 dbSNP
rs1275560747 559 dbSNP
rs949657617 579 dbSNP
rs1320701344 580 dbSNP
rs961690236 583 dbSNP
rs1238995816 594 dbSNP
rs1232202667 596 dbSNP
rs972128785 608 dbSNP
rs774288088 616 dbSNP
rs1439499015 620 dbSNP
rs181145278 622 dbSNP
rs1329373451 631 dbSNP
rs1466983182 652 dbSNP
rs767451928 656 dbSNP
rs185555041 661 dbSNP
rs189633619 668 dbSNP
rs759423174 672 dbSNP
rs937839035 677 dbSNP
rs1414560072 688 dbSNP
rs1183826848 697 dbSNP
rs766307749 713 dbSNP
rs753353950 716 dbSNP
rs1468734823 719 dbSNP
rs754468132 731 dbSNP
rs1179717940 737 dbSNP
rs1459352014 754 dbSNP
rs145125110 762 dbSNP
rs182316819 772 dbSNP
rs945340645 774 dbSNP
rs1334931708 802 dbSNP
rs199840810 806 dbSNP
rs1221569118 819 dbSNP
rs996648018 823 dbSNP
rs1449563320 825 dbSNP
rs1372228637 835 dbSNP
rs1279745638 839 dbSNP
rs1448766236 843 dbSNP
rs187728449 848 dbSNP
rs192123995 854 dbSNP
rs1461846750 864 dbSNP
rs1350547121 868 dbSNP
rs998230976 870 dbSNP
rs1049845144 874 dbSNP
rs767335008 880 dbSNP
rs1399011903 882 dbSNP
rs889906641 895 dbSNP
rs1006130041 939 dbSNP
rs1159443143 949 dbSNP
rs1017124307 958 dbSNP
rs1251462421 960 dbSNP
rs1193562451 971 dbSNP
rs1489130853 976 dbSNP
rs1008489871 986 dbSNP
rs1015485735 990 dbSNP
rs897372732 991 dbSNP
rs1470732422 992 dbSNP
rs1302337478 994 dbSNP
rs1441365286 995 dbSNP
rs1160705657 996 dbSNP
rs994450286 1004 dbSNP
rs1287026309 1012 dbSNP
rs1025899646 1019 dbSNP
rs1428770390 1020 dbSNP
rs970377241 1024 dbSNP
rs1344644799 1029 dbSNP
rs1299045832 1031 dbSNP
rs1421681016 1032 dbSNP
rs981776806 1048 dbSNP
rs747379696 1050 dbSNP
rs752533217 1053 dbSNP
rs760496762 1054 dbSNP
rs959140111 1077 dbSNP
rs1185245315 1078 dbSNP
rs1027030353 1093 dbSNP
rs989707007 1094 dbSNP
rs1406619532 1099 dbSNP
rs959428123 1105 dbSNP
rs184069868 1120 dbSNP
rs1484525815 1125 dbSNP
rs1279148194 1126 dbSNP
rs1233770526 1134 dbSNP
rs376110775 1144 dbSNP
rs1293388844 1147 dbSNP
rs945260749 1154 dbSNP
rs1361363462 1158 dbSNP
rs1278989466 1164 dbSNP
rs1025495118 1174 dbSNP
rs970898432 1175 dbSNP
rs1312465179 1197 dbSNP
rs781721479 1201 dbSNP
rs1466900706 1215 dbSNP
rs1239475813 1216 dbSNP
rs752238002 1220 dbSNP
rs770489152 1222 dbSNP
rs978035444 1229 dbSNP
rs924161475 1232 dbSNP
rs371155054 1234 dbSNP
rs1473928023 1244 dbSNP
rs936958955 1245 dbSNP
rs922562686 1247 dbSNP
rs1484125418 1250 dbSNP
rs1249335842 1254 dbSNP
rs933971512 1258 dbSNP
rs1318590452 1261 dbSNP
rs746003874 1272 dbSNP
rs889855829 1278 dbSNP
rs1353598304 1280 dbSNP
rs1312303778 1290 dbSNP
rs1396757534 1292 dbSNP
rs188225222 1322 dbSNP
rs775644866 1327 dbSNP
rs1296881648 1332 dbSNP
rs932379129 1333 dbSNP
rs1401726769 1343 dbSNP
rs1173422734 1347 dbSNP
rs763290436 1351 dbSNP
rs1459444528 1361 dbSNP
rs1416464235 1364 dbSNP
rs756725974 1367 dbSNP
rs1425255432 1368 dbSNP
rs941468736 1368 dbSNP
rs1247963003 1369 dbSNP
rs1458020155 1378 dbSNP
rs1038921435 1382 dbSNP
rs1184424987 1392 dbSNP
rs1332780092 1403 dbSNP
rs897325106 1405 dbSNP
rs890887602 1408 dbSNP
rs768900201 1414 dbSNP
rs943845908 1416 dbSNP
rs193171872 1434 dbSNP
rs897064875 1444 dbSNP
rs1378061016 1452 dbSNP
rs1333979811 1453 dbSNP
rs1024506729 1463 dbSNP
rs760512962 1463 dbSNP
rs1390639980 1464 dbSNP
rs72039883 1464 dbSNP
rs778515290 1465 dbSNP
rs184061229 1466 dbSNP
rs1239706334 1467 dbSNP
rs1191670155 1469 dbSNP
rs1468033980 1470 dbSNP
rs1395646131 1471 dbSNP
rs753823884 1473 dbSNP
rs759398618 1478 dbSNP
rs1026976524 1479 dbSNP
rs1239635617 1491 dbSNP
rs1354883955 1496 dbSNP
rs1003146141 1498 dbSNP
rs1338491824 1507 dbSNP
rs1324745295 1512 dbSNP
rs1388040742 1515 dbSNP
rs1033336119 1524 dbSNP
rs187292243 1540 dbSNP
rs989261476 1541 dbSNP
rs750997308 1546 dbSNP
rs191383825 1547 dbSNP
rs1361221517 1570 dbSNP
rs1419855372 1578 dbSNP
rs1335529944 1585 dbSNP
rs1171593293 1590 dbSNP
rs966575296 1605 dbSNP
rs6529391 1611 dbSNP
rs780683990 1618 dbSNP
rs183954204 1633 dbSNP
rs140737792 1634 dbSNP
rs143024098 1639 dbSNP
rs958264557 1649 dbSNP
rs1442234058 1658 dbSNP
rs1288398747 1664 dbSNP
rs989718821 1670 dbSNP
rs10324 1675 dbSNP
rs769057497 1676 dbSNP
rs941403599 1677 dbSNP
rs1245174566 1680 dbSNP
rs922199827 1682 dbSNP
rs1277089381 1686 dbSNP
rs868652194 1700 dbSNP
rs1168031184 1702 dbSNP
rs932310661 1729 dbSNP
rs985531727 1730 dbSNP
rs1413734380 1748 dbSNP
rs781271716 1756 dbSNP
rs189459375 1761 dbSNP
rs1462375880 1765 dbSNP
rs897266514 1771 dbSNP
rs545811830 1779 dbSNP
rs1399732918 1787 dbSNP
rs1422826249 1789 dbSNP
rs930159767 1792 dbSNP
rs1045902115 1793 dbSNP
rs907453367 1798 dbSNP
rs7065704 1806 dbSNP
rs181944376 1807 dbSNP
rs199921535 1809 dbSNP
rs894811559 1825 dbSNP
rs1279696450 1826 dbSNP
rs1384543737 1836 dbSNP
rs1338076703 1845 dbSNP
rs1257958703 1847 dbSNP
rs1218758085 1850 dbSNP
rs1011036504 1852 dbSNP
rs112009247 1853 dbSNP
rs1446762743 1855 dbSNP
rs966900996 1858 dbSNP
rs55781374 1865 dbSNP
rs1294168427 1869 dbSNP
rs1399509718 1880 dbSNP
rs1171249073 1885 dbSNP
rs1466227435 1899 dbSNP
rs999341111 1905 dbSNP
rs1180339087 1909 dbSNP
rs1472628267 1922 dbSNP
rs1238252075 1932 dbSNP
rs1190113506 1950 dbSNP
rs1456698233 1954 dbSNP
rs1029530155 1961 dbSNP
rs769789029 1963 dbSNP
rs985378703 1969 dbSNP
rs1270662079 1978 dbSNP
rs1307569147 1980 dbSNP
rs1356683193 1982 dbSNP
rs911180326 2013 dbSNP
rs1285559619 2018 dbSNP
rs773239644 2021 dbSNP
rs185748363 2036 dbSNP
rs189873198 2042 dbSNP
rs1331970082 2043 dbSNP
rs1448811416 2046 dbSNP
rs974522026 2056 dbSNP
rs1254783808 2064 dbSNP
rs1012216805 2092 dbSNP
rs918663478 2094 dbSNP
rs1025431211 2101 dbSNP
rs1165185578 2126 dbSNP
rs768825288 2154 dbSNP
rs1237897524 2157 dbSNP
rs774617260 2164 dbSNP
rs1179819441 2167 dbSNP
rs1459531346 2170 dbSNP
rs748257020 2178 dbSNP
rs1045849793 2179 dbSNP
rs928824001 2189 dbSNP
rs1463700281 2204 dbSNP
rs1065276 2209 dbSNP
rs937552947 2221 dbSNP
rs866579856 2222 dbSNP
rs1262471606 2240 dbSNP
rs1352717965 2240 dbSNP
rs893410235 2246 dbSNP
rs1430405895 2253 dbSNP
rs906615628 2253 dbSNP
rs1368757901 2282 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gacaagagaaggaAACCGGAAc 5'
                       |||||||| 
Target 5' -------------UUGGCCUUu 3'
 		1 - 9
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000371113.4 | 3UTR | UUGGCCUUUUCAUGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
94 hsa-miR-4753-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT064916 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT161166 SLC25A36 solute carrier family 25 member 36 2 2
MIRT285542 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT308266 LRIG1 leucine rich repeats and immunoglobulin like domains 1 2 2
MIRT311425 LMNB1 lamin B1 2 2
MIRT373989 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT383141 CRY2 cryptochrome circadian clock 2 2 2
MIRT405243 ADIPOR2 adiponectin receptor 2 2 2
MIRT441620 ROCK1 Rho associated coiled-coil containing protein kinase 1 2 6
MIRT441789 SRPK1 SRSF protein kinase 1 2 2
MIRT441804 NOC3L NOC3 like DNA replication regulator 2 2
MIRT441832 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT442005 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT442411 LIMD1 LIM domains containing 1 2 2
MIRT442708 UBE4B ubiquitination factor E4B 2 2
MIRT442714 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT442738 SERINC5 serine incorporator 5 2 2
MIRT442793 CEP170 centrosomal protein 170 2 2
MIRT442984 ZNF736 zinc finger protein 736 2 2
MIRT443055 THRB thyroid hormone receptor beta 2 2
MIRT443288 ZC3H12A zinc finger CCCH-type containing 12A 2 2
MIRT443325 SLC35G1 solute carrier family 35 member G1 2 2
MIRT443331 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT443593 ZNF439 zinc finger protein 439 2 4
MIRT443696 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT443748 ELL2 elongation factor for RNA polymerase II 2 2 2
MIRT443866 HDLBP high density lipoprotein binding protein 2 2
MIRT461185 LTBP2 latent transforming growth factor beta binding protein 2 2 2
MIRT464074 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT468738 SDC4 syndecan 4 2 2
MIRT470540 COASY Coenzyme A synthase 2 2
MIRT476458 GBA2 glucosylceramidase beta 2 2 2
MIRT479470 CDK6 cyclin dependent kinase 6 2 2
MIRT486351 TACC2 transforming acidic coiled-coil containing protein 2 2 8
MIRT495126 CXorf67 chromosome X open reading frame 67 2 2
MIRT495166 CNGA2 cyclic nucleotide gated channel alpha 2 2 4
MIRT495432 ATG7 autophagy related 7 2 2
MIRT495922 FBXO41 F-box protein 41 2 2
MIRT496572 DGCR6L DiGeorge syndrome critical region gene 6 like 2 2
MIRT498277 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT498431 DDX39A DExD-box helicase 39A 2 2
MIRT530149 HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 2
MIRT530313 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT530880 TRUB1 TruB pseudouridine synthase family member 1 2 4
MIRT531177 ZNF626 zinc finger protein 626 2 2
MIRT533395 TYRP1 tyrosinase related protein 1 2 2
MIRT533709 TMEM64 transmembrane protein 64 2 2
MIRT533954 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 2
MIRT535616 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT539472 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT542878 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT559077 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT559465 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT561233 ZNF772 zinc finger protein 772 2 2
MIRT563477 POLE3 DNA polymerase epsilon 3, accessory subunit 2 2
MIRT563995 SLFN11 schlafen family member 11 2 2
MIRT564222 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT566017 RHOA ras homolog family member A 2 2
MIRT566028 RFX1 regulatory factor X1 2 2
MIRT566591 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT567874 CTDSP1 CTD small phosphatase 1 2 2
MIRT568552 AKT2 AKT serine/threonine kinase 2 2 2
MIRT569357 EFHC1 EF-hand domain containing 1 2 2
MIRT569973 DNAAF2 dynein axonemal assembly factor 2 2 2
MIRT614423 ZNF440 zinc finger protein 440 2 2
MIRT628831 SLC25A34 solute carrier family 25 member 34 2 2
MIRT630142 ZFYVE9 zinc finger FYVE-type containing 9 2 2
MIRT634479 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 2
MIRT634498 OR7D2 olfactory receptor family 7 subfamily D member 2 2 2
MIRT637394 R3HDM2 R3H domain containing 2 2 2
MIRT641840 TCF7L2 transcription factor 7 like 2 2 2
MIRT644397 CDKL1 cyclin dependent kinase like 1 2 2
MIRT644888 C2orf50 chromosome 2 open reading frame 50 2 2
MIRT647124 ZNF446 zinc finger protein 446 2 2
MIRT647420 SSTR3 somatostatin receptor 3 2 2
MIRT650297 PYCARD PYD and CARD domain containing 2 2
MIRT655488 PAK3 p21 (RAC1) activated kinase 3 2 2
MIRT658185 FBXO9 F-box protein 9 2 2
MIRT660931 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT665317 ZBTB3 zinc finger and BTB domain containing 3 2 2
MIRT670350 C1orf106 chromosome 1 open reading frame 106 2 4
MIRT670823 NICN1 nicolin 1 2 2
MIRT671825 TRPM6 transient receptor potential cation channel subfamily M member 6 2 2
MIRT672732 NETO2 neuropilin and tolloid like 2 2 2
MIRT674841 GLRX2 glutaredoxin 2 2 2
MIRT675930 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT686786 AZF1 azoospermia factor 1 2 2
MIRT697723 USP8 ubiquitin specific peptidase 8 2 2
MIRT702357 KLHL26 kelch like family member 26 2 2
MIRT704361 DBR1 debranching RNA lariats 1 2 2
MIRT709242 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT714433 SNED1 sushi, nidogen and EGF like domains 1 2 2
MIRT717000 ARL6IP4 ADP ribosylation factor like GTPase 6 interacting protein 4 2 2
MIRT720875 ADCY5 adenylate cyclase 5 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4753 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4753-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4753-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4753-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4753-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4753-5p Platinum 23939 resistant tissue
hsa-miR-4753-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4753-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4753-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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