miRTarBase - #MIRT443526


—
pre-miRNA Information
pre-miRNA hsa-mir-4722   
Genomic Coordinates chr16: 88716278 - 88716337
Description Homo sapiens miR-4722 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4722-5p
Sequence 1| GGCAGGAGGGCUGUGCCAGGUUG |23
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1327113111 2 dbSNP
rs774516383 3 dbSNP
rs1353403500 6 dbSNP
rs768834483 11 dbSNP
rs938540081 13 dbSNP
rs557265812 14 dbSNP
rs1411163724 16 dbSNP
rs928486875 20 dbSNP
rs1172652034 21 dbSNP
rs942739465 23 dbSNP
Putative Targets

Gene Information
Gene Symbol ACAP2   
Synonyms CENTB2, CNT-B2
Description ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Transcript NM_012287   
Expression
Putative miRNA Targets on ACAP2
3'UTR of ACAP2
(miRNA target sites are highlighted)		 
>ACAP2|NM_012287|3'UTR
   1 ATTTTTTTAAAAATGGGAAAATATGAAATCTGGTGACCCCCTAATGTATACAGCTAAAAAATCACAATTTTTTTACTGCT
  81 TTAATTCTACTTAATTTTGGTAGATATTGAATGGCTTGGAAAAGAGGTACCCATTCATATATTTATAAATTAAAACATAG
 161 TTATCTAGTAGTAGGAGAGGAACCTAGTTTAGGACCTCTTTTATTAAAAAAGCCTATTTAAAGGGCTATTTCTGTAGACA
 241 GAAGTTCAGTCTAGATTTAGGCCATCTCTAGGTTACAAGATGATAGGAGGTTAGACAAAAGTGATTCTTTTGCCAATGGG
 321 TGGTGGCATTGATTTTTTTCCTCCATGCATCTTGCCCAGGATCACTCAGTCAAGCATGTCTTCATCAAGTGGAAGCCAAC
 401 TGTCCTGCCTGCCTCAAGAATATGTGTTTTCTTTAGCTTCCCTGAGGCTTTTTGGTGGTTCAGAAATAGGTGTGTGTGTT
 481 GATGTGTTTTTGGTAACCTAGCTTTCATACACATAATATATGATTTATTAGAACTAGAGAATGTGTTTTCCCCGTTTGTT
 561 CATAAATGCGGTCGGTTATACTTCTTAGGTGACAGGTTATTGTCCAGTACTTTAATGTATGTATGTATAATGGCTGTACA
 641 GGTAGACCATAATTCAGTCCTTTAGATTTATTTTATGCAGCAAAAAGAAGCTCTTTTTTTTTTTTAATCACAAAAAAAAA
 721 CCCCAGTTCAAAATGTGTAGTTCTTCATTGTTGGGTTGATTCCCCAAAACCTTGACAGATGTATCGATGGAATAAAAGTA
 801 TGTTTTAAAGGTTACTTGAATGTCACAAAATTATGCCTTCATCAAAACTTTAAAGGAAAAATCAATTTATAAAATCATGT
 881 AGGCCATTTTTATATTTGAAATTTGTCCTTTTAAAGATAGTTTTGCTGTTGCTCCTAGTGAAAGAAAAATCTCTGTACAA
 961 AGGAGAAAAAGAACCCCACTTATTCTTAGTTAATACTAAAATATATAGCAATAAATTGCTGTTTATTTTTTCTACATCTA
1041 TTTTGTGTACTTGTACACAGTGTACATTCTTTTAAATTATATCGTGTATATAGCTTTAGTATTCGGTTACATGATTCACA
1121 GACCCCTGAATTCCAAAATATTATGGATAAACATTACCATTTATATGCTACAAATTAGTCTGATTCCATCTTTGAAAATG
1201 TCTTAAAGTATAAAATAATTAATTTGCTTTTTTTTTTTTTTTTTCCCGAGATGGCGTCTTGCTGTGTCACCCAGGCTGGA
1281 GTGCAGTGGCACGATCTCAGCTCACTGCAGCCTCCTCCTCTTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAG
1361 CTGGGACTACAGGCACCCGCCACCATTCCGAGCTAATTTCTATATTTTTAGTAAAGACGGGTTTCACCATTTTGGCCAGG
1441 TTGGTCTCGAACTCCTGACCTCAGGTGATCAGCCTGCTTTAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGC
1521 ACCCAGCCTAATTTGCCTTTTGATTCCTTCCCATTGTTGTCAACAATTAAGTCTATTCTTCTTTTAGAAATTATATGTAA
1601 ATGATATTATTGATACTCTTTCTAAATAAGAGGTTTTAAAATATATAAAAACTTTATGATCCAATTATAGATAAATTTTC
1681 TAACATTTCCCAGTCACTAGGGTTTTATAAGTTGATTAAACATCAAATCAGAATCTAGCCAAGCAGGAATTATATTGAAA
1761 TAAGTTCACATTACAGAAAAGGTTCCATAATTTGGCCAAACTGCATGCATGTAATGCTTATTTAGTAATGGTCACTGTAT
1841 GTTAGATAAGGATAAAAATATATTTGTGAATTACTTCTGAGGAAATGCTAACTTCCACAGCATTGTATTTAATTATAACA
1921 ATAACAGGAACATTAAATCTTTATCTTTGCTGTTTCACCTCAAAGTCATAGATCATCTGGCTTTTTAGGCACCTTCACTA
2001 AAGGCAAAAATCTGATTTGTAGTTTTTATTAGCATGTACCTTGAAATTATTTGACCAAGAAGCTCAAAGAAAAGAAGTAC
2081 GTTAAAGAAAAAGAAAAAACCTCACTTTTCCTTTATAGTGTCCCTTCCTGTTTTAATTCCTAAAGATCCTGACTTTTATC
2161 TGAGGAAGTCTAGGTAGTTTTCCTTTTGGATCTGGCCATTGGTGCGTGTTTCATTCAGATCACCTCTGGAATCTCTGTGG
2241 TTGTGAAGGCAATTCCTTATGAGACTCTTGCCTCCTGTGGCTTACGTGATGAATTGTTAATATGGCAGTAATTAATTAGT
2321 ATCTACTTAAATTTAGTGGTCAGAAATGTATTTGAAGTGCCTTAAAGATGATCATGGTTCAGAATATCTTCAGAGAAAGC
2401 AAAATCTTTAATATTGCAGGGAGCCTAGCAATACAAGTACACATTTCTGTGGCTTGATTTCTTGAATATGCTGAGACCCA
2481 ATTTGGACTACATTTGGCAGAAATGATGGAGTAAACAGCAAGGCTTTAAATTAAATTAATAGTTACAAGGTAGGTTGGCT
2561 CTTAGGTGAATTTAGCCATGTCAACTAATAGCTTTTATATGGTATGTAACAAATCTGAATTATGTTATGCTGTGAATTAT
2641 TCAGTGCATTATAAGAAATCTTAGTTAATCATGCTTTTGGGCTTCATTAGTCAATGTGATTGGCCTTTTATTTTCTTTCC
2721 ATAACTTATCTGCTATTATTAGTTTCTTATTCCTTATTATTAATCTGTTAGCTCATTATCATTAGCTTACTAACTTGAAA
2801 GTTAGATTAATATCAAAATAAGAATAGCAGCACTATGAAGAGTTAATAAAATGCAATTTCATGTTAGAGCTAGAATAAAA
2881 GTAATTGAGCAGTCATTTGCAAATGCTTCATTATAACATTTATGTGCTTAAGATTTCTAAGGTTTTAAAAAGTTACCTTT
2961 AATACAATCCTTAGAAACTCAGAAATTTCCTGATATTCATTAGATTATGGTGTTTGCCTAATTTATACCGGTTTTCACTG
3041 TATATTTTAATGAACTTTGATTGGTTACTTTTCCAGACATACAGATTTAATTTGGAATATGAACTTTGGTTCTTCATGAG
3121 TGCATTTTGAAAAAGAAAAAAAGTACACATTCAGAATCTGGCCAATTTAAGTTTGTATTTTAAAAATATTTTATGCATGT
3201 TAAGTATGGTCGCAGTAAATGAAATTGTGTTTAAGACTAAATTTACTACCGTTTTGAACAGACATTCCCAGATCATTCTT
3281 ATATTGTCAGATAACACTTGTGTATAATATCACTTTGGATCATGGACATGAGCTGGAAAAATGATGTATTTTTGTAGATT
3361 GTATGTCCAGAATGACTTTAGAACCGCATGATACGGTGGAAGGAGCACTGGACTAGTCGTCACTACCCTTTTTGGATTCA
3441 GGGCTCCTCACAATTAAAATGAGTGTAATGAAACAAGGTGAAAATATAGAAGCATCCCTTTGTATACTGTTTTGCTACTT
3521 ACAGTGTACTTGGCATTGCTTTATCTCACTGGATTCTCATGGTAGGATTTCTGAGATCTTAATCTAAGCTCCAAAGTTGT
3601 CTACTTTTTTGATCCTAGGGTGCTCCTTTTGTTTTACAGAGCAGGGTCACTTGATTTGCTAGCTGGTGGCAGAATTGGCA
3681 CCATTACCCAGGTCTGACTGACCACCAGTCAGAGGCACTTTATTTGTATCATGAAATGATTTGAAATCATTGTAAAGCAG
3761 CGAAGTCTGATAATGAATGCCAGCTTTCCTTGTGCTTTGATAACAAAGACTCCAAATATTCTGGAGAACCTGGATAAAAG
3841 TTTGAAGGGCTAGATTGGGATTTGAAGACAAAATTGTAGGAAATCTTACATTTTTGCAATAACAAACATTAATGAAAGCA
3921 AAACATTATAAAAGTAATTTTAATTCACCACATACTTATCAATTTCTTGATGCTTCCAAATGACATCTACAGATATGGTT
4001 TTGTGGACATCTTTTTCTGTTTACATAAATTTATCCACTTAAAATGTGATAATGTGGAGACAAAGCAAGATTTGATTACA
4081 TAAACTTTTCTCTGCATTGGTCTTTTCACTATCTTATTTGCTAACTTTTCTTATTTTTCTTCAACCTCCCCACCCTCCAT
4161 TTTTTGGATATTAAACAGGGAAAGCTTGCTACATTATAAAGATTGTTGGCACCATTTATTTTACACAAAGGCTAAAGGTT
4241 AACTTTTGGAAATGATGAGCTACTTTTATATATGTGTTTACTCATGCTTTGTGATATTTCTGGATCATTCCAGTCATAAA
4321 GACTTATTACATGTACTATTTCTTGCTACCTGTGAAAAGGTATATTTTAAAGAATGTATAACCAACAGTCCATTTACTTT
4401 TTATTAGTATGTAGAGGATTTGTATCTAATTCATGAATGTAGTTTTACAGTAGTTTGTCATTGTAAATGGAGCAAAGTAC
4481 ATTATCTTCTAAAATGTACATTATGTAAGAATTGTAAATATACTTAAGTAATTTGTATGCCAAAAAATTACAATAAGTCA
4561 ATAAAGATCTCACCTCTGGCTTAGTTCTTTCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guuGGACC---GU--GUCGGGAGGACGg 5'
             |:|||   ||  || ::||||||| 
Target 5' cctCTTGGGTTCAAGCAATTCTCCTGCc 3'
 1317 - 1344 158.00 -25.00
2 
miRNA  3' guugGACCGUGUCGGGAGGACgg 5'
              :|||: : |  ||||||  
Target 5' caggTTGGTCTCGAACTCCTGac 3'
 1437 - 1459 131.00 -18.20
3 
miRNA  3' guuggaccgugucgGGAGGACGg 5'
                        |||||||: 
Target 5' ttatgagactcttgCCTCCTGTg 3'
 2257 - 2279 129.00 -13.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31570157 1 COSMIC
COSN30165950 8 COSMIC
COSN30643102 8 COSMIC
COSN30126013 9 COSMIC
COSN26964794 34 COSMIC
COSN30501716 43 COSMIC
COSN30158206 64 COSMIC
COSN30701000 64 COSMIC
COSN30566340 67 COSMIC
COSN30670414 68 COSMIC
COSN31522250 72 COSMIC
COSN22225391 100 COSMIC
COSN32180040 383 COSMIC
COSN17205647 569 COSMIC
COSN1939874 585 COSMIC
COSN20099567 694 COSMIC
COSN20638199 721 COSMIC
COSN9543016 1025 COSMIC
COSN25157926 1040 COSMIC
COSN7599760 1240 COSMIC
COSN18764489 1243 COSMIC
COSN20099566 1244 COSMIC
COSN15300542 1248 COSMIC
COSN5531959 1476 COSMIC
COSN5042500 1700 COSMIC
COSN9718075 1735 COSMIC
COSN1939872 1855 COSMIC
COSN15167728 1977 COSMIC
COSN25386644 2338 COSMIC
COSN24095742 3030 COSMIC
COSN9718074 3192 COSMIC
COSN31569658 3212 COSMIC
COSN28687446 3421 COSMIC
COSN30169390 4159 COSMIC
COSN31520392 4254 COSMIC
COSN31549457 4321 COSMIC
COSN26677355 4330 COSMIC
COSN31536223 4350 COSMIC
COSN29714276 4474 COSMIC
COSN28752088 4507 COSMIC
COSN17181878 4514 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781493746 1 dbSNP
rs548974427 4 dbSNP
rs1281357979 6 dbSNP
rs530487889 8 dbSNP
rs775047492 9 dbSNP
rs1398664542 13 dbSNP
rs35467154 13 dbSNP
rs1342893773 14 dbSNP
rs563151430 21 dbSNP
rs1432724109 24 dbSNP
rs1447619781 24 dbSNP
rs1330866780 27 dbSNP
rs778946405 33 dbSNP
rs757308901 36 dbSNP
rs1397990452 38 dbSNP
rs753369388 39 dbSNP
rs938258769 40 dbSNP
rs1179972638 45 dbSNP
rs1334459152 49 dbSNP
rs781054933 49 dbSNP
rs1312033299 60 dbSNP
rs7610022 61 dbSNP
rs1253629950 62 dbSNP
rs1045359206 63 dbSNP
rs188024325 67 dbSNP
rs1256927708 75 dbSNP
rs565472532 77 dbSNP
rs1456168510 80 dbSNP
rs1195153559 88 dbSNP
rs1267759190 89 dbSNP
rs1432405801 90 dbSNP
rs747017320 91 dbSNP
rs775424292 102 dbSNP
rs957177962 107 dbSNP
rs1184735247 108 dbSNP
rs878876724 118 dbSNP
rs1170054648 145 dbSNP
rs1398256882 158 dbSNP
rs994075641 160 dbSNP
rs777676424 164 dbSNP
rs72607898 166 dbSNP
rs1385456592 175 dbSNP
rs1298294532 179 dbSNP
rs573185914 180 dbSNP
rs1341662815 187 dbSNP
rs941210794 188 dbSNP
rs1276985274 201 dbSNP
rs964975096 204 dbSNP
rs1050571875 212 dbSNP
rs149109156 212 dbSNP
rs1252636520 214 dbSNP
rs1243586342 217 dbSNP
rs1207830797 226 dbSNP
rs1263668896 228 dbSNP
rs1478089605 237 dbSNP
rs561274857 238 dbSNP
rs1192922511 240 dbSNP
rs1421515141 240 dbSNP
rs72607897 241 dbSNP
rs1165667973 249 dbSNP
rs1349528463 253 dbSNP
rs1456632135 255 dbSNP
rs143217988 262 dbSNP
rs1361619287 264 dbSNP
rs1399908325 266 dbSNP
rs1315706389 270 dbSNP
rs976092229 281 dbSNP
rs1337717189 285 dbSNP
rs935294974 286 dbSNP
rs1248041067 290 dbSNP
rs924194310 292 dbSNP
rs1242209905 295 dbSNP
rs1008835258 307 dbSNP
rs979648608 308 dbSNP
rs1488509814 310 dbSNP
rs529099377 313 dbSNP
rs182606387 316 dbSNP
rs994913384 324 dbSNP
rs1486659384 325 dbSNP
rs1390835066 326 dbSNP
rs990609339 328 dbSNP
rs960724043 329 dbSNP
rs1300108440 331 dbSNP
rs899285970 338 dbSNP
rs1034703520 340 dbSNP
rs1419513220 342 dbSNP
rs1384975640 349 dbSNP
rs539079158 358 dbSNP
rs1164568302 364 dbSNP
rs1447003676 375 dbSNP
rs1449493654 380 dbSNP
rs993813967 386 dbSNP
rs1377875799 387 dbSNP
rs1393885376 388 dbSNP
rs1180477806 390 dbSNP
rs12485302 393 dbSNP
rs1354069416 408 dbSNP
rs1016840525 424 dbSNP
rs1239178010 424 dbSNP
rs1252299976 442 dbSNP
rs1219773680 446 dbSNP
rs3087885 448 dbSNP
rs1292264934 453 dbSNP
rs748435994 458 dbSNP
rs1236953615 459 dbSNP
rs889648227 466 dbSNP
rs906714085 474 dbSNP
rs192099350 486 dbSNP
rs1439382330 496 dbSNP
rs945641129 498 dbSNP
rs1278815245 509 dbSNP
rs912891883 512 dbSNP
rs1157229015 513 dbSNP
rs1052761344 519 dbSNP
rs1040444807 520 dbSNP
rs1290494732 527 dbSNP
rs762171242 547 dbSNP
rs187295078 553 dbSNP
rs935329347 554 dbSNP
rs549262702 557 dbSNP
rs1306764720 561 dbSNP
rs779112408 569 dbSNP
rs1369522295 570 dbSNP
rs149149854 573 dbSNP
rs974913051 574 dbSNP
rs755276736 576 dbSNP
rs1310447382 585 dbSNP
rs751439092 596 dbSNP
rs1158484915 598 dbSNP
rs964551078 601 dbSNP
rs569586578 603 dbSNP
rs1364998730 605 dbSNP
rs946940915 606 dbSNP
rs1478581100 607 dbSNP
rs1196601487 618 dbSNP
rs1423704958 619 dbSNP
rs1467699710 621 dbSNP
rs1172183103 636 dbSNP
rs1400438117 637 dbSNP
rs987350658 639 dbSNP
rs916784489 643 dbSNP
rs767988495 649 dbSNP
rs1351363813 661 dbSNP
rs991410204 662 dbSNP
rs1274116095 663 dbSNP
rs960882947 675 dbSNP
rs1220440015 681 dbSNP
rs762069042 682 dbSNP
rs973451459 687 dbSNP
rs182752205 688 dbSNP
rs1317399577 691 dbSNP
rs972447591 697 dbSNP
rs1445062154 705 dbSNP
rs1221282677 706 dbSNP
rs1479069903 706 dbSNP
rs34509351 706 dbSNP
rs961067090 706 dbSNP
rs1195090099 707 dbSNP
rs1423657615 708 dbSNP
rs1283542193 709 dbSNP
rs1016536420 710 dbSNP
rs1351543132 711 dbSNP
rs1270120888 712 dbSNP
rs1221705690 713 dbSNP
rs1347955196 718 dbSNP
rs1345125934 719 dbSNP
rs564333715 720 dbSNP
rs1286089697 721 dbSNP
rs1339854559 721 dbSNP
rs889712831 721 dbSNP
rs190626262 727 dbSNP
rs1227997856 732 dbSNP
rs559217672 735 dbSNP
rs998427722 737 dbSNP
rs900974909 745 dbSNP
rs1263105656 757 dbSNP
rs1040517353 760 dbSNP
rs999611077 761 dbSNP
rs546768167 765 dbSNP
rs1472909735 771 dbSNP
rs1325026967 773 dbSNP
rs1162308963 778 dbSNP
rs146635487 785 dbSNP
rs946710093 786 dbSNP
rs1401829797 791 dbSNP
rs1359814144 799 dbSNP
rs1025133577 802 dbSNP
rs1055343758 816 dbSNP
rs1341191481 818 dbSNP
rs1447508800 823 dbSNP
rs1009773113 824 dbSNP
rs1468770215 834 dbSNP
rs1429638583 836 dbSNP
rs1241341225 842 dbSNP
rs73890752 845 dbSNP
rs1202756835 847 dbSNP
rs1257598921 853 dbSNP
rs1052707969 860 dbSNP
rs935654514 861 dbSNP
rs763579593 863 dbSNP
rs1442529003 865 dbSNP
rs904207154 867 dbSNP
rs1186321880 873 dbSNP
rs542874513 876 dbSNP
rs961099233 877 dbSNP
rs1441228272 878 dbSNP
rs1474330073 879 dbSNP
rs1241270264 881 dbSNP
rs1193580336 884 dbSNP
rs1451508487 890 dbSNP
rs943118086 906 dbSNP
rs1174263979 907 dbSNP
rs1402949165 912 dbSNP
rs113331960 920 dbSNP
rs141418578 920 dbSNP
rs74476062 926 dbSNP
rs984210471 932 dbSNP
rs185370606 934 dbSNP
rs1322905473 942 dbSNP
rs1264042440 953 dbSNP
rs1334376945 954 dbSNP
rs11928860 966 dbSNP
rs545115068 974 dbSNP
rs1257104080 978 dbSNP
rs919203421 979 dbSNP
rs1337651604 980 dbSNP
rs998106108 985 dbSNP
rs965245987 992 dbSNP
rs1458795840 996 dbSNP
rs973740454 1006 dbSNP
rs1270004730 1008 dbSNP
rs1431857129 1018 dbSNP
rs1417110614 1034 dbSNP
rs1200825554 1037 dbSNP
rs145908931 1044 dbSNP
rs796443762 1047 dbSNP
rs1451354170 1052 dbSNP
rs1174364751 1053 dbSNP
rs762560167 1065 dbSNP
rs1406141778 1066 dbSNP
rs1394704091 1068 dbSNP
rs1388901752 1073 dbSNP
rs1302485003 1080 dbSNP
rs1331031208 1081 dbSNP
rs114325690 1083 dbSNP
rs1407888412 1084 dbSNP
rs1319411249 1088 dbSNP
rs1025082768 1090 dbSNP
rs1257033774 1092 dbSNP
rs1479500947 1095 dbSNP
rs1211397879 1098 dbSNP
rs181331463 1104 dbSNP
rs557038776 1105 dbSNP
rs541595441 1106 dbSNP
rs1425816151 1117 dbSNP
rs939585739 1118 dbSNP
rs372278830 1121 dbSNP
rs1371545741 1128 dbSNP
rs928162939 1139 dbSNP
rs573837311 1142 dbSNP
rs775734705 1143 dbSNP
rs1390531297 1144 dbSNP
rs1403582417 1146 dbSNP
rs1300617487 1151 dbSNP
rs555602194 1152 dbSNP
rs1001525309 1163 dbSNP
rs878981008 1172 dbSNP
rs566466763 1173 dbSNP
rs904152310 1176 dbSNP
rs1305396316 1188 dbSNP
rs759362183 1190 dbSNP
rs1037174810 1201 dbSNP
rs1265787508 1205 dbSNP
rs1490134312 1207 dbSNP
rs1460959737 1208 dbSNP
rs1372029545 1209 dbSNP
rs1265267145 1211 dbSNP
rs1243858490 1219 dbSNP
rs1212273620 1222 dbSNP
rs1436303161 1226 dbSNP
rs1272474048 1227 dbSNP
rs1215592157 1228 dbSNP
rs1344740124 1238 dbSNP
rs1313610621 1241 dbSNP
rs1245838374 1242 dbSNP
rs1384128562 1243 dbSNP
rs9874644 1244 dbSNP
rs11923271 1245 dbSNP
rs200248324 1245 dbSNP
rs774973683 1245 dbSNP
rs1399998113 1247 dbSNP
rs1312995283 1248 dbSNP
rs200598935 1248 dbSNP
rs745535630 1248 dbSNP
rs752009039 1248 dbSNP
rs1358392137 1250 dbSNP
rs1439315220 1253 dbSNP
rs538938969 1255 dbSNP
rs1354294265 1256 dbSNP
rs1215047809 1257 dbSNP
rs1258992295 1262 dbSNP
rs1484293215 1263 dbSNP
rs1182594091 1264 dbSNP
rs940168969 1266 dbSNP
rs1180892407 1276 dbSNP
rs909624008 1278 dbSNP
rs35684667 1287 dbSNP
rs1419603324 1288 dbSNP
rs1039142921 1290 dbSNP
rs1160162182 1292 dbSNP
rs537347251 1293 dbSNP
rs1342860538 1298 dbSNP
rs1467146739 1299 dbSNP
rs1302982119 1302 dbSNP
rs983852400 1305 dbSNP
rs1450064877 1315 dbSNP
rs1311157322 1317 dbSNP
rs1383120081 1321 dbSNP
rs953879019 1323 dbSNP
rs1223108604 1329 dbSNP
rs1282066279 1330 dbSNP
rs920937620 1331 dbSNP
rs976689307 1332 dbSNP
rs1415805223 1334 dbSNP
rs1262658583 1339 dbSNP
rs943129016 1344 dbSNP
rs1239118003 1352 dbSNP
rs890232654 1354 dbSNP
rs1183674159 1355 dbSNP
rs1051582190 1359 dbSNP
rs1434322380 1365 dbSNP
rs929094816 1367 dbSNP
rs1232580852 1369 dbSNP
rs375838495 1370 dbSNP
rs1033119521 1375 dbSNP
rs1467862565 1377 dbSNP
rs1206110796 1378 dbSNP
rs919110173 1379 dbSNP
rs973310938 1381 dbSNP
rs1441219756 1388 dbSNP
rs113038029 1389 dbSNP
rs926643056 1390 dbSNP
rs1010987442 1392 dbSNP
rs1222148105 1400 dbSNP
rs1360802461 1403 dbSNP
rs981204264 1418 dbSNP
rs970775666 1424 dbSNP
rs1371959711 1426 dbSNP
rs917973444 1448 dbSNP
rs140654761 1449 dbSNP
rs956832799 1454 dbSNP
rs1248862942 1467 dbSNP
rs1489082259 1468 dbSNP
rs1032929560 1470 dbSNP
rs1427945306 1471 dbSNP
rs1001114934 1476 dbSNP
rs118104988 1480 dbSNP
rs1017250626 1488 dbSNP
rs1409076369 1489 dbSNP
rs1326568818 1491 dbSNP
rs1363278014 1505 dbSNP
rs1037205891 1508 dbSNP
rs146836053 1509 dbSNP
rs1437045520 1510 dbSNP
rs1302506476 1515 dbSNP
rs149830474 1518 dbSNP
rs72607896 1519 dbSNP
rs993249089 1530 dbSNP
rs142920402 1535 dbSNP
rs200914605 1535 dbSNP
rs1213084817 1537 dbSNP
rs897654548 1547 dbSNP
rs111689638 1553 dbSNP
rs1399077432 1562 dbSNP
rs7632534 1564 dbSNP
rs567377985 1575 dbSNP
rs1473706480 1584 dbSNP
rs1267391559 1592 dbSNP
rs1489587641 1593 dbSNP
rs1266965417 1606 dbSNP
rs926563458 1611 dbSNP
rs779236841 1616 dbSNP
rs867404691 1618 dbSNP
rs1199234749 1620 dbSNP
rs779057378 1621 dbSNP
rs1415641705 1623 dbSNP
rs1267809792 1625 dbSNP
rs1425070604 1627 dbSNP
rs1214240412 1630 dbSNP
rs1162758284 1633 dbSNP
rs976431051 1642 dbSNP
rs943664704 1644 dbSNP
rs1298864725 1645 dbSNP
rs549214193 1661 dbSNP
rs1316807394 1669 dbSNP
rs924527690 1671 dbSNP
rs1428845603 1674 dbSNP
rs1286183656 1676 dbSNP
rs1284375936 1677 dbSNP
rs73206669 1679 dbSNP
rs1290130398 1687 dbSNP
rs1343262938 1693 dbSNP
rs968994330 1697 dbSNP
rs1190494287 1700 dbSNP
rs1445949922 1700 dbSNP
rs1238856271 1701 dbSNP
rs1282233726 1702 dbSNP
rs369787678 1704 dbSNP
rs1182718504 1707 dbSNP
rs1383205013 1717 dbSNP
rs1405389319 1724 dbSNP
rs1369432406 1738 dbSNP
rs563864715 1752 dbSNP
rs917921255 1757 dbSNP
rs1384255758 1762 dbSNP
rs988149014 1763 dbSNP
rs1021437986 1764 dbSNP
rs1453005044 1767 dbSNP
rs1345663518 1782 dbSNP
rs545702203 1792 dbSNP
rs1452246394 1799 dbSNP
rs1313348230 1802 dbSNP
rs1379605260 1812 dbSNP
rs1241459614 1830 dbSNP
rs989997425 1836 dbSNP
rs1160017436 1839 dbSNP
rs959494512 1845 dbSNP
rs956818005 1862 dbSNP
rs777729933 1898 dbSNP
rs1461471103 1905 dbSNP
rs533137191 1914 dbSNP
rs980031413 1915 dbSNP
rs1441316552 1920 dbSNP
rs559792114 1921 dbSNP
rs1175950036 1931 dbSNP
rs1363140894 1932 dbSNP
rs1468602296 1936 dbSNP
rs1018913433 1945 dbSNP
rs1174362975 1952 dbSNP
rs1434158795 1957 dbSNP
rs1269959715 1961 dbSNP
rs1008501800 1962 dbSNP
rs1004420177 1965 dbSNP
rs1469441493 1982 dbSNP
rs888636492 1987 dbSNP
rs1048542847 1994 dbSNP
rs527824044 1996 dbSNP
rs748033357 1998 dbSNP
rs1249121275 2000 dbSNP
rs1334476017 2003 dbSNP
rs1236132248 2004 dbSNP
rs1276057168 2010 dbSNP
rs1323661109 2014 dbSNP
rs1030036682 2015 dbSNP
rs899601429 2019 dbSNP
rs1320776959 2024 dbSNP
rs1260875490 2025 dbSNP
rs1040779229 2030 dbSNP
rs749641874 2034 dbSNP
rs780342974 2035 dbSNP
rs924267904 2047 dbSNP
rs897594557 2055 dbSNP
rs1200943824 2058 dbSNP
rs185908878 2067 dbSNP
rs947310191 2075 dbSNP
rs914443130 2076 dbSNP
rs1322452681 2078 dbSNP
rs879383727 2080 dbSNP
rs756641791 2081 dbSNP
rs1388989632 2094 dbSNP
rs1345530840 2099 dbSNP
rs1403782359 2100 dbSNP
rs958744296 2100 dbSNP
rs1308866326 2101 dbSNP
rs1227773834 2108 dbSNP
rs905045478 2114 dbSNP
rs1044923329 2123 dbSNP
rs1337241788 2129 dbSNP
rs1211497646 2130 dbSNP
rs1269539267 2140 dbSNP
rs750832214 2148 dbSNP
rs560282908 2157 dbSNP
rs555590037 2169 dbSNP
rs1379533995 2171 dbSNP
rs1168784246 2172 dbSNP
rs13325136 2179 dbSNP
rs1371630118 2183 dbSNP
rs1459778339 2192 dbSNP
rs1004900827 2202 dbSNP
rs114091684 2205 dbSNP
rs979552639 2206 dbSNP
rs997029598 2209 dbSNP
rs757936410 2221 dbSNP
rs557740161 2226 dbSNP
rs911396875 2229 dbSNP
rs1363486045 2235 dbSNP
rs1382400519 2249 dbSNP
rs899967962 2250 dbSNP
rs1324413322 2254 dbSNP
rs1247882830 2256 dbSNP
rs752290502 2285 dbSNP
rs1242017819 2286 dbSNP
rs1358615052 2300 dbSNP
rs987016837 2301 dbSNP
rs1281452125 2304 dbSNP
rs1040851864 2313 dbSNP
rs1186087944 2314 dbSNP
rs955648022 2316 dbSNP
rs1200481936 2318 dbSNP
rs764948993 2319 dbSNP
rs1029984385 2325 dbSNP
rs1385061343 2336 dbSNP
rs902877780 2347 dbSNP
rs1226508075 2352 dbSNP
rs1346391052 2357 dbSNP
rs1041414794 2359 dbSNP
rs971753144 2366 dbSNP
rs1287843994 2371 dbSNP
rs1382320374 2376 dbSNP
rs1454284155 2390 dbSNP
rs1315415701 2395 dbSNP
rs1235857534 2397 dbSNP
rs1243592507 2399 dbSNP
rs1342582323 2406 dbSNP
rs961752086 2414 dbSNP
rs1243724446 2415 dbSNP
rs1259077696 2429 dbSNP
rs2000052 2437 dbSNP
rs1204577945 2449 dbSNP
rs1336181330 2460 dbSNP
rs776470746 2469 dbSNP
rs1443175864 2473 dbSNP
rs565296918 2477 dbSNP
rs1404706784 2487 dbSNP
rs1409339234 2491 dbSNP
rs1419072820 2492 dbSNP
rs1296653237 2493 dbSNP
rs1461836636 2494 dbSNP
rs1157697946 2499 dbSNP
rs2000051 2505 dbSNP
rs928467625 2506 dbSNP
rs982185517 2507 dbSNP
rs112238038 2510 dbSNP
rs970774224 2510 dbSNP
rs982822112 2522 dbSNP
rs867063431 2523 dbSNP
rs1223192832 2546 dbSNP
rs1170825777 2549 dbSNP
rs1325799295 2566 dbSNP
rs1224287513 2570 dbSNP
rs1262770779 2576 dbSNP
rs1027247452 2577 dbSNP
rs1385092978 2584 dbSNP
rs896428965 2596 dbSNP
rs1480579858 2597 dbSNP
rs1187643116 2599 dbSNP
rs1364609964 2605 dbSNP
rs1248898983 2613 dbSNP
rs1481138596 2624 dbSNP
rs1176598064 2625 dbSNP
rs772962821 2640 dbSNP
rs935298886 2648 dbSNP
rs1467941618 2651 dbSNP
rs180962700 2659 dbSNP
rs1354921901 2663 dbSNP
rs1441349347 2664 dbSNP
rs1296390993 2669 dbSNP
rs150959757 2672 dbSNP
rs1405617490 2673 dbSNP
rs757735654 2687 dbSNP
rs1321635916 2694 dbSNP
rs1216599049 2695 dbSNP
rs942806916 2696 dbSNP
rs190500723 2697 dbSNP
rs1274103467 2705 dbSNP
rs1219908834 2715 dbSNP
rs570244242 2725 dbSNP
rs1307288887 2736 dbSNP
rs75802045 2742 dbSNP
rs986991394 2747 dbSNP
rs1284709339 2749 dbSNP
rs1019779291 2750 dbSNP
rs1008369231 2752 dbSNP
rs1245691697 2764 dbSNP
rs1267611490 2765 dbSNP
rs1476807408 2767 dbSNP
rs1187936132 2769 dbSNP
rs902951292 2778 dbSNP
rs934218976 2793 dbSNP
rs1041817834 2798 dbSNP
rs1305179384 2806 dbSNP
rs918814506 2807 dbSNP
rs142505426 2830 dbSNP
rs754995273 2833 dbSNP
rs1343747130 2840 dbSNP
rs1433076019 2843 dbSNP
rs1271005683 2847 dbSNP
rs1361597121 2848 dbSNP
rs1351282867 2853 dbSNP
rs892784650 2854 dbSNP
rs961976721 2856 dbSNP
rs1222425909 2860 dbSNP
rs867942314 2860 dbSNP
rs984941997 2861 dbSNP
rs937238296 2862 dbSNP
rs1217423563 2881 dbSNP
rs1423058101 2885 dbSNP
rs969202642 2906 dbSNP
rs928501887 2913 dbSNP
rs1343661250 2924 dbSNP
rs1164326956 2928 dbSNP
rs1445117105 2933 dbSNP
rs1023405023 2952 dbSNP
rs1459031977 2953 dbSNP
rs1162857090 2956 dbSNP
rs1013399494 2985 dbSNP
rs896335724 2998 dbSNP
rs370490565 2999 dbSNP
rs1180403154 3003 dbSNP
rs999450620 3007 dbSNP
rs774463624 3016 dbSNP
rs768852726 3021 dbSNP
rs903818467 3028 dbSNP
rs1344794431 3029 dbSNP
rs1428941408 3030 dbSNP
rs1317549131 3042 dbSNP
rs559778913 3055 dbSNP
rs185690906 3063 dbSNP
rs1245801591 3064 dbSNP
rs1253447284 3075 dbSNP
rs1197101824 3080 dbSNP
rs908638144 3082 dbSNP
rs1490122019 3095 dbSNP
rs1290563399 3097 dbSNP
rs942761613 3099 dbSNP
rs983241273 3108 dbSNP
rs1446043815 3109 dbSNP
rs889903497 3116 dbSNP
rs529389502 3120 dbSNP
rs1049646 3122 dbSNP
rs1244705548 3130 dbSNP
rs1461612322 3139 dbSNP
rs1182817741 3143 dbSNP
rs1366640624 3163 dbSNP
rs1051194806 3165 dbSNP
rs1471141714 3171 dbSNP
rs934125660 3171 dbSNP
rs952778646 3180 dbSNP
rs1407376048 3181 dbSNP
rs1338948033 3187 dbSNP
rs1455802666 3187 dbSNP
rs1259057655 3205 dbSNP
rs918763596 3206 dbSNP
rs1227798358 3211 dbSNP
rs113473451 3212 dbSNP
rs1338019958 3218 dbSNP
rs1290438501 3221 dbSNP
rs1279584702 3228 dbSNP
rs1349372062 3231 dbSNP
rs1226128379 3237 dbSNP
rs1264600668 3245 dbSNP
rs139504936 3250 dbSNP
rs576128428 3251 dbSNP
rs984495608 3254 dbSNP
rs1324575145 3255 dbSNP
rs969529508 3276 dbSNP
rs916301799 3282 dbSNP
rs1157781668 3283 dbSNP
rs991887514 3287 dbSNP
rs1471661067 3291 dbSNP
rs1178750266 3304 dbSNP
rs1469521693 3306 dbSNP
rs1413798279 3309 dbSNP
rs960488154 3315 dbSNP
rs9863901 3320 dbSNP
rs1349243237 3323 dbSNP
rs192076446 3328 dbSNP
rs968015638 3330 dbSNP
rs1323777417 3332 dbSNP
rs1022705328 3333 dbSNP
rs1253980362 3348 dbSNP
rs1341213248 3357 dbSNP
rs1196243466 3359 dbSNP
rs1011738014 3361 dbSNP
rs1482073993 3363 dbSNP
rs780329256 3363 dbSNP
rs1201653167 3364 dbSNP
rs1006863740 3367 dbSNP
rs892825528 3368 dbSNP
rs1375075700 3373 dbSNP
rs907749013 3375 dbSNP
rs1034418653 3379 dbSNP
rs1462802071 3380 dbSNP
rs555640950 3385 dbSNP
rs568535567 3386 dbSNP
rs998280067 3390 dbSNP
rs897322989 3391 dbSNP
rs372099981 3394 dbSNP
rs1270304680 3395 dbSNP
rs1221948055 3398 dbSNP
rs1227883924 3405 dbSNP
rs1296656483 3406 dbSNP
rs753189836 3407 dbSNP
rs1047185105 3408 dbSNP
rs1292541399 3410 dbSNP
rs1490208991 3413 dbSNP
rs931371730 3419 dbSNP
rs746270997 3429 dbSNP
rs941586913 3435 dbSNP
rs540323925 3442 dbSNP
rs975835742 3451 dbSNP
rs1388729979 3461 dbSNP
rs1446927369 3464 dbSNP
rs910162590 3470 dbSNP
rs1320463562 3484 dbSNP
rs553346269 3487 dbSNP
rs1435250978 3491 dbSNP
rs1390159210 3507 dbSNP
rs947699305 3507 dbSNP
rs1334069930 3508 dbSNP
rs1413573087 3523 dbSNP
rs942636153 3532 dbSNP
rs147427115 3536 dbSNP
rs1425361579 3558 dbSNP
rs574176924 3560 dbSNP
rs546516090 3562 dbSNP
rs912824905 3566 dbSNP
rs555960026 3591 dbSNP
rs987042941 3593 dbSNP
rs868157635 3594 dbSNP
rs967578195 3597 dbSNP
rs991836708 3604 dbSNP
rs1020853248 3609 dbSNP
rs781752106 3614 dbSNP
rs1486288858 3621 dbSNP
rs189260404 3625 dbSNP
rs1246498842 3626 dbSNP
rs1462945048 3637 dbSNP
rs1184655548 3638 dbSNP
rs923767744 3645 dbSNP
rs1372490520 3647 dbSNP
rs957362702 3651 dbSNP
rs1034079317 3666 dbSNP
rs1189111655 3667 dbSNP
rs1319477712 3668 dbSNP
rs977980109 3675 dbSNP
rs1454366598 3678 dbSNP
rs1337192161 3681 dbSNP
rs968299860 3684 dbSNP
rs906846280 3687 dbSNP
rs1022190328 3688 dbSNP
rs879200583 3698 dbSNP
rs1394241678 3699 dbSNP
rs1024212318 3700 dbSNP
rs199712162 3718 dbSNP
rs775693897 3719 dbSNP
rs1227950845 3726 dbSNP
rs752229180 3733 dbSNP
rs1201790805 3735 dbSNP
rs1431222999 3745 dbSNP
rs953995645 3761 dbSNP
rs886300075 3762 dbSNP
rs1029705195 3777 dbSNP
rs1442066350 3779 dbSNP
rs1204681451 3789 dbSNP
rs1237319425 3792 dbSNP
rs1482537019 3802 dbSNP
rs144481711 3816 dbSNP
rs551993798 3822 dbSNP
rs1016166061 3833 dbSNP
rs1005691530 3843 dbSNP
rs1409269246 3858 dbSNP
rs1470779001 3861 dbSNP
rs540136005 3867 dbSNP
rs1044613877 3868 dbSNP
rs948981607 3869 dbSNP
rs566405594 3871 dbSNP
rs1464419726 3876 dbSNP
rs1299826310 3879 dbSNP
rs1374038695 3888 dbSNP
rs1229824387 3890 dbSNP
rs557451696 3899 dbSNP
rs1056096941 3902 dbSNP
rs1446556887 3909 dbSNP
rs1278317436 3913 dbSNP
rs1359448503 3918 dbSNP
rs1207170995 3919 dbSNP
rs1252394268 3923 dbSNP
rs1335765389 3930 dbSNP
rs1483054737 3936 dbSNP
rs939091408 3942 dbSNP
rs1408045839 3959 dbSNP
rs754651937 3959 dbSNP
rs1191417481 3961 dbSNP
rs1369681875 3966 dbSNP
rs867820363 3979 dbSNP
rs946266935 3984 dbSNP
rs1383231746 3989 dbSNP
rs753364237 3990 dbSNP
rs946531061 3991 dbSNP
rs913457178 3996 dbSNP
rs140633884 4002 dbSNP
rs1306209695 4006 dbSNP
rs765837731 4010 dbSNP
rs1238320403 4011 dbSNP
rs1405711264 4012 dbSNP
rs1212476943 4023 dbSNP
rs1274499820 4024 dbSNP
rs1436249404 4025 dbSNP
rs143986348 4038 dbSNP
rs953981061 4046 dbSNP
rs1206237689 4066 dbSNP
rs979816716 4077 dbSNP
rs1344936715 4083 dbSNP
rs1029648112 4085 dbSNP
rs976780721 4091 dbSNP
rs539432550 4101 dbSNP
rs1015657375 4102 dbSNP
rs1221731856 4106 dbSNP
rs1004787173 4108 dbSNP
rs1476858354 4111 dbSNP
rs1188026249 4112 dbSNP
rs1006054795 4114 dbSNP
rs1390586400 4119 dbSNP
rs1439601307 4125 dbSNP
rs888589046 4146 dbSNP
rs184136099 4151 dbSNP
rs35425902 4152 dbSNP
rs1027532643 4166 dbSNP
rs1323056450 4167 dbSNP
rs1348330787 4170 dbSNP
rs1013119327 4172 dbSNP
rs1289776040 4179 dbSNP
rs1431396160 4184 dbSNP
rs1317758064 4185 dbSNP
rs900323354 4210 dbSNP
rs896095683 4212 dbSNP
rs1363704334 4223 dbSNP
rs1163967652 4231 dbSNP
rs1404881934 4240 dbSNP
rs531841960 4247 dbSNP
rs1414668089 4257 dbSNP
rs1057328823 4258 dbSNP
rs1248345043 4270 dbSNP
rs938996512 4274 dbSNP
rs1464287805 4276 dbSNP
rs1183621669 4283 dbSNP
rs555213625 4284 dbSNP
rs1387010960 4295 dbSNP
rs1006961076 4304 dbSNP
rs1162686356 4305 dbSNP
rs891160251 4310 dbSNP
rs191639838 4316 dbSNP
rs187992034 4327 dbSNP
rs571822176 4330 dbSNP
rs1054680335 4331 dbSNP
rs985311822 4332 dbSNP
rs1339148689 4351 dbSNP
rs936202431 4358 dbSNP
rs1447974706 4359 dbSNP
rs1283048352 4362 dbSNP
rs927466358 4364 dbSNP
rs1225055403 4367 dbSNP
rs1268359660 4379 dbSNP
rs979846352 4385 dbSNP
rs560048140 4393 dbSNP
rs149512120 4397 dbSNP
rs1291423727 4403 dbSNP
rs1442890883 4410 dbSNP
rs1186752892 4411 dbSNP
rs1235746370 4422 dbSNP
rs574051139 4432 dbSNP
rs916971942 4443 dbSNP
rs983080858 4446 dbSNP
rs1411469593 4449 dbSNP
rs528249453 4450 dbSNP
rs1028016545 4463 dbSNP
rs994761723 4463 dbSNP
rs1288575223 4471 dbSNP
rs964925966 4499 dbSNP
rs1332786336 4508 dbSNP
rs767420997 4509 dbSNP
rs976685939 4524 dbSNP
rs1411488042 4529 dbSNP
rs1017435603 4532 dbSNP
rs1349474707 4536 dbSNP
rs1226220415 4540 dbSNP
rs1008706152 4547 dbSNP
rs1345465094 4548 dbSNP
rs961363964 4553 dbSNP
rs138794212 4554 dbSNP
rs1439532878 4557 dbSNP
rs984215433 4561 dbSNP
rs537536782 4574 dbSNP
rs1251200408 4578 dbSNP
rs1471711767 4579 dbSNP
rs1201866904 4583 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guugGACC---GU--GUCGGGAGGAcgg 5'
              :|||   ||  || ::|||||   
Target 5' ----UUGGGUUCAAGCAAUUCUCCU--- 3'
 		1 - 21
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23527.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guuggaccgugucggGAGGACGg 5'
                         :||  || 
Target 5' ----------uugggUUCAAGCa 3'
 		1 - 13
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM4903830
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / CTLTD_shCTL_b
Location of target site NM_012287 | 3UTR | UCCUCCUCUUGGGUUCAAGCAAUUCUCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_012287 | 3UTR | CAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGGCACCCGCCACCAUUCCGAGCUAAUUUCUAUAUUUUUAGUAAAGACGGGUUUCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_012287 | 3UTR | CAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGGCACCCGCCACCAUUCCGAGCUAAUUUCUAUAUUUUUAGUAAAGACGGGUUUCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_012287 | 3UTR | GUUCAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGGCACCCGCCACCAUUCCGAGCUAAUUUCUAUAUUUUUAGUAAAGACGGGUUUCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_012287 | 3UTR | UUCAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGGCACCCGCCACCAUUCCGAGCUAAUUUCUAUAUUUUUAGUAAAGACGGGUUUCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_012287 | 3UTR | CAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGGCACCCGCCACCAUUCCGAGCUAAUUUCUAUAUUUUUAGUAAAGACGGGUUUCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_012287 | 3UTR | GGGUUCAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGGCACCCGCCACCAUUCCGAGCUAAUUUCUAUAUUUUUAGUAAAGACGGGUUUCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000326793.6 | 3UTR | UUGGGUUCAAGCAAUUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000326793.6 | 3UTR | UUGGGUUCAAGCAAUUCUCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
451 hsa-miR-4722-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT054597 SNCG synuclein gamma 3 1
MIRT082999 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT140189 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT143139 MGRN1 mahogunin ring finger 1 2 2
MIRT150114 MIDN midnolin 2 2
MIRT153929 NCOA3 nuclear receptor coactivator 3 2 2
MIRT200999 ZNF805 zinc finger protein 805 2 2
MIRT214002 DCP2 decapping mRNA 2 2 2
MIRT292480 ZNF507 zinc finger protein 507 2 2
MIRT325575 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT370125 TRIB3 tribbles pseudokinase 3 2 2
MIRT442143 C20orf197 chromosome 20 open reading frame 197 2 2
MIRT443495 MXI1 MAX interactor 1, dimerization protein 2 6
MIRT443526 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 4
MIRT445688 GJB1 gap junction protein beta 1 2 2
MIRT447187 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 4
MIRT448070 SLC25A43 solute carrier family 25 member 43 2 2
MIRT448198 B4GALT7 beta-1,4-galactosyltransferase 7 2 4
MIRT451251 ZNF444 zinc finger protein 444 2 2
MIRT451291 ZNF101 zinc finger protein 101 2 4
MIRT451455 HSD11B1L hydroxysteroid 11-beta dehydrogenase 1 like 2 2
MIRT451503 ALOX15 arachidonate 15-lipoxygenase 2 2
MIRT451752 LRTM2 leucine rich repeats and transmembrane domains 2 2 2
MIRT452056 ZNF585B zinc finger protein 585B 2 12
MIRT452211 HAVCR1 hepatitis A virus cellular receptor 1 2 8
MIRT452575 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT452724 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 4
MIRT452736 PTGES3L prostaglandin E synthase 3 like 2 8
MIRT452760 TCEA3 transcription elongation factor A3 2 4
MIRT452868 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT452879 PRSS45 protease, serine 45 2 2
MIRT452967 ZNF844 zinc finger protein 844 2 8
MIRT453023 ZNF527 zinc finger protein 527 2 4
MIRT453060 TANGO2 transport and golgi organization 2 homolog 2 2
MIRT453480 PITPNM3 PITPNM family member 3 2 2
MIRT453706 TBX20 T-box 20 2 2
MIRT453904 GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 2 4
MIRT453967 ATP13A4 ATPase 13A4 2 6
MIRT454061 SLC35E3 solute carrier family 35 member E3 2 2
MIRT454246 CCDC125 coiled-coil domain containing 125 2 2
MIRT454481 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454529 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454986 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT455482 NPY4R neuropeptide Y receptor Y4 2 2
MIRT455698 ZMYM1 zinc finger MYM-type containing 1 2 4
MIRT455929 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT456207 LIX1L limb and CNS expressed 1 like 2 6
MIRT456274 HRNR hornerin 2 2
MIRT456417 MTRF1L mitochondrial translational release factor 1 like 2 2
MIRT456732 TMEM239 transmembrane protein 239 2 2
MIRT456993 ZNF669 zinc finger protein 669 2 4
MIRT457132 ASPH aspartate beta-hydroxylase 2 2
MIRT457239 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457283 PCDHB11 protocadherin beta 11 2 2
MIRT457338 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 2 2
MIRT457471 SLC35F6 solute carrier family 35 member F6 2 2
MIRT457542 ZC3H6 zinc finger CCCH-type containing 6 2 2
MIRT457640 ZNF69 zinc finger protein 69 2 2
MIRT457981 APAF1 apoptotic peptidase activating factor 1 2 4
MIRT458183 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT458453 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT458461 SNX22 sorting nexin 22 2 6
MIRT458507 GSG2 histone H3 associated protein kinase 2 6
MIRT458557 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT458637 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT458783 ZNF786 zinc finger protein 786 2 2
MIRT458795 CYP8B1 cytochrome P450 family 8 subfamily B member 1 2 2
MIRT459052 ZNF490 zinc finger protein 490 2 2
MIRT459398 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT459547 BTD biotinidase 2 4
MIRT460145 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT460163 CCL16 C-C motif chemokine ligand 16 2 2
MIRT460243 IL17RB interleukin 17 receptor B 2 4
MIRT460356 TXNDC16 thioredoxin domain containing 16 2 4
MIRT460512 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460613 FEM1A fem-1 homolog A 2 2
MIRT460713 FN3KRP fructosamine 3 kinase related protein 2 2
MIRT460799 VPS33A VPS33A, CORVET/HOPS core subunit 2 2
MIRT460829 EGF epidermal growth factor 2 4
MIRT460931 NOA1 nitric oxide associated 1 2 2
MIRT461113 PACSIN2 protein kinase C and casein kinase substrate in neurons 2 2 2
MIRT461124 RAB36 RAB36, member RAS oncogene family 2 4
MIRT461150 RAB2A RAB2A, member RAS oncogene family 2 2
MIRT461200 TIPIN TIMELESS interacting protein 2 2
MIRT461463 SLC19A3 solute carrier family 19 member 3 2 2
MIRT461812 SNAP23 synaptosome associated protein 23 2 2
MIRT462078 MSANTD2 Myb/SANT DNA binding domain containing 2 2 2
MIRT462213 MLH1 mutL homolog 1 2 2
MIRT462308 TMEM109 transmembrane protein 109 2 2
MIRT462430 GTPBP10 GTP binding protein 10 2 4
MIRT462503 MTFMT mitochondrial methionyl-tRNA formyltransferase 2 8
MIRT462535 PLLP plasmolipin 2 6
MIRT462691 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT462908 ZNRF3 zinc and ring finger 3 2 2
MIRT462964 ZNF788 zinc finger family member 788 2 2
MIRT463066 ZNF639 zinc finger protein 639 2 4
MIRT463868 WNT7B Wnt family member 7B 2 2
MIRT464036 WASL Wiskott-Aldrich syndrome like 2 2
MIRT464115 VPS35 VPS35, retromer complex component 2 2
MIRT464507 UCK2 uridine-cytidine kinase 2 2 2
MIRT464931 TXLNA taxilin alpha 2 2
MIRT465203 TRMT6 tRNA methyltransferase 6 2 2
MIRT465579 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT466090 TMEM184C transmembrane protein 184C 2 2
MIRT466208 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT467010 SSBP2 single stranded DNA binding protein 2 2 4
MIRT467159 SREBF2 sterol regulatory element binding transcription factor 2 2 2
MIRT467754 SLC35F1 solute carrier family 35 member F1 2 4
MIRT467843 SLC25A34 solute carrier family 25 member 34 2 2
MIRT468139 SH3BP4 SH3 domain binding protein 4 2 2
MIRT469034 RNF38 ring finger protein 38 2 6
MIRT469062 RNF20 ring finger protein 20 2 2
MIRT469280 RHOA ras homolog family member A 2 2
MIRT469584 RAP2B RAP2B, member of RAS oncogene family 2 6
MIRT470108 PTBP2 polypyrimidine tract binding protein 2 2 6
MIRT470186 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT470282 PRDX5 peroxiredoxin 5 2 2
MIRT471059 PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2 2
MIRT471160 PHF12 PHD finger protein 12 2 2
MIRT471337 PERP PERP, TP53 apoptosis effector 2 2
MIRT471573 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT471643 PANK2 pantothenate kinase 2 2 4
MIRT472028 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT472319 NF2 neurofibromin 2 2 2
MIRT472821 MTMR10 myotubularin related protein 10 2 4
MIRT473101 MLXIP MLX interacting protein 2 2
MIRT473292 MFRP membrane frizzled-related protein 2 2
MIRT473635 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT474108 LMBR1L limb development membrane protein 1 like 2 2
MIRT474615 KLF2 Kruppel like factor 2 2 4
MIRT474666 KLF13 Kruppel like factor 13 2 4
MIRT474696 KIF5A kinesin family member 5A 2 2
MIRT474818 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT475280 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT475650 HIF3A hypoxia inducible factor 3 alpha subunit 2 4
MIRT475703 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT475762 HDLBP high density lipoprotein binding protein 2 2
MIRT476382 GID4 GID complex subunit 4 homolog 2 4
MIRT476398 GDE1 glycerophosphodiester phosphodiesterase 1 2 8
MIRT476446 GBA2 glucosylceramidase beta 2 2 2
MIRT476804 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT477074 FAM208A family with sequence similarity 208 member A 2 4
MIRT477152 FADS1 fatty acid desaturase 1 2 8
MIRT477247 ERGIC2 ERGIC and golgi 2 2 2
MIRT477543 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT478088 DLGAP4 DLG associated protein 4 2 2
MIRT478226 DDX52 DExD-box helicase 52 2 2
MIRT478751 CS citrate synthase 2 2
MIRT479196 CLCN5 chloride voltage-gated channel 5 2 6
MIRT479908 CCDC117 coiled-coil domain containing 117 2 6
MIRT480198 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2 2
MIRT480437 C17orf49 chromosome 17 open reading frame 49 2 2
MIRT480722 BPTF bromodomain PHD finger transcription factor 2 4
MIRT481096 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT481429 ASB6 ankyrin repeat and SOCS box containing 6 2 4
MIRT482080 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT482256 AGO3 argonaute 3, RISC catalytic component 2 4
MIRT482342 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482463 ADAR adenosine deaminase, RNA specific 2 4
MIRT483780 CASKIN1 CASK interacting protein 1 2 4
MIRT484384 ZNF710 zinc finger protein 710 2 4
MIRT485110 SHISA6 shisa family member 6 2 2
MIRT487430 ZSCAN25 zinc finger and SCAN domain containing 25 2 4
MIRT487519 GXYLT2 glucoside xylosyltransferase 2 2 4
MIRT487911 FBXO44 F-box protein 44 2 2
MIRT487961 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT488496 SFMBT2 Scm like with four mbt domains 2 2 4
MIRT488595 SPN sialophorin 2 2
MIRT488994 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT490265 HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2 2
MIRT490835 ADD2 adducin 2 2 2
MIRT490863 UPK2 uroplakin 2 2 2
MIRT491481 APC2 APC2, WNT signaling pathway regulator 2 6
MIRT491713 C17orf85 nuclear cap binding subunit 3 2 2
MIRT492571 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 4
MIRT495792 GRK1 G protein-coupled receptor kinase 1 2 4
MIRT496285 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT496791 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT498599 KRT8 keratin 8 2 2
MIRT498734 SNTN sentan, cilia apical structure protein 2 6
MIRT500016 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501616 PISD phosphatidylserine decarboxylase 2 2
MIRT502160 KIAA1109 KIAA1109 2 4
MIRT502319 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT503238 C16orf74 chromosome 16 open reading frame 74 2 4
MIRT503427 SLC25A45 solute carrier family 25 member 45 2 6
MIRT503871 CBS cystathionine-beta-synthase 2 2
MIRT505181 USP46 ubiquitin specific peptidase 46 2 4
MIRT505402 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 4
MIRT507338 FAM168A family with sequence similarity 168 member A 2 2
MIRT508899 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT516506 SYTL3 synaptotagmin like 3 2 4
MIRT516528 MIXL1 Mix paired-like homeobox 2 2
MIRT517214 PRIM1 DNA primase subunit 1 2 4
MIRT517972 DSCR3 DSCR3 arrestin fold containing 2 2
MIRT518902 CDC14B cell division cycle 14B 2 2
MIRT519272 ZNF141 zinc finger protein 141 2 4
MIRT520332 UBXN2A UBX domain protein 2A 2 2
MIRT524620 C7orf73 short transmembrane mitochondrial protein 1 2 2
MIRT525322 SNX29 sorting nexin 29 2 2
MIRT529045 CDK18 cyclin dependent kinase 18 2 2
MIRT533852 TEAD1 TEA domain transcription factor 1 2 2
MIRT536401 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT546465 SLC25A44 solute carrier family 25 member 44 2 2
MIRT548657 CTTNBP2NL CTTNBP2 N-terminal like 2 2
MIRT549906 ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 2 2
MIRT550418 ORC4 origin recognition complex subunit 4 2 2
MIRT550571 SLC2A5 solute carrier family 2 member 5 2 2
MIRT550592 CBY3 chibby family member 3 2 2
MIRT550771 ENOX2 ecto-NOX disulfide-thiol exchanger 2 2 4
MIRT550988 RBM38 RNA binding motif protein 38 2 2
MIRT551332 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT551393 MRI1 methylthioribose-1-phosphate isomerase 1 2 4
MIRT553919 STK11IP serine/threonine kinase 11 interacting protein 2 2
MIRT554616 RPS6KA3 ribosomal protein S6 kinase A3 2 2
MIRT559202 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT559537 ARHGAP1 Rho GTPase activating protein 1 2 2
MIRT559650 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT560141 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT562318 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT564496 PUS3 pseudouridylate synthase 3 2 2
MIRT566253 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT567619 FAM210A family with sequence similarity 210 member A 2 2
MIRT567950 CREBZF CREB/ATF bZIP transcription factor 2 2
MIRT568011 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT574884 Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 2 2
MIRT575559 Cd99 CD99 antigen 2 2
MIRT576147 Hmox1 heme oxygenase 1 2 2
MIRT608269 NOP14 NOP14 nucleolar protein 2 2
MIRT610850 ARSA arylsulfatase A 2 2
MIRT614128 THAP1 THAP domain containing 1 2 6
MIRT614722 TEAD3 TEA domain transcription factor 3 2 2
MIRT615227 BROX BRO1 domain and CAAX motif containing 2 2
MIRT617419 ANP32E acidic nuclear phosphoprotein 32 family member E 2 4
MIRT618170 ZNF681 zinc finger protein 681 2 4
MIRT618873 MBL2 mannose binding lectin 2 2 2
MIRT618974 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619184 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620310 AQP6 aquaporin 6 2 2
MIRT620422 CD3EAP CD3e molecule associated protein 2 2
MIRT620451 CENPN centromere protein N 2 2
MIRT621649 UBXN2B UBX domain protein 2B 2 2
MIRT621951 STX7 syntaxin 7 2 2
MIRT622815 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT623357 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT624916 FBXW2 F-box and WD repeat domain containing 2 2 2
MIRT624979 ZNF665 zinc finger protein 665 2 4
MIRT625490 SMAD9 SMAD family member 9 2 2
MIRT625587 KLHL23 kelch like family member 23 2 2
MIRT625656 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT625879 INADL PATJ, crumbs cell polarity complex component 2 2
MIRT626231 ZNF749 zinc finger protein 749 2 2
MIRT626621 SLC30A6 solute carrier family 30 member 6 2 2
MIRT626986 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627055 DCTN6 dynactin subunit 6 2 2
MIRT627674 RPL28 ribosomal protein L28 2 2
MIRT627887 OLFML2A olfactomedin like 2A 2 2
MIRT627981 NDRG3 NDRG family member 3 2 2
MIRT628313 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT628343 CCDC68 coiled-coil domain containing 68 2 2
MIRT631946 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632270 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT636356 OGFRL1 opioid growth factor receptor like 1 2 2
MIRT639187 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT639668 PPEF2 protein phosphatase with EF-hand domain 2 2 6
MIRT639865 STK40 serine/threonine kinase 40 2 2
MIRT642230 RABAC1 Rab acceptor 1 2 2
MIRT642364 ZNF581 zinc finger protein 581 2 2
MIRT646793 EVC2 EvC ciliary complex subunit 2 2 2
MIRT646977 KCNJ11 potassium voltage-gated channel subfamily J member 11 2 2
MIRT647068 BRIX1 BRX1, biogenesis of ribosomes 2 4
MIRT647310 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT648993 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT649132 SPATA5 spermatogenesis associated 5 2 2
MIRT650524 CCDC77 coiled-coil domain containing 77 2 4
MIRT650986 ZNF770 zinc finger protein 770 2 2
MIRT655721 NRXN3 neurexin 3 2 2
MIRT657564 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT659811 CASP16 caspase 16, pseudogene 2 2
MIRT660471 ARSK arylsulfatase family member K 2 2
MIRT661131 ZNF43 zinc finger protein 43 2 2
MIRT661193 MPPE1 metallophosphoesterase 1 2 2
MIRT661429 MANSC1 MANSC domain containing 1 2 2
MIRT661545 ZNF674 zinc finger protein 674 2 4
MIRT661669 ZNF623 zinc finger protein 623 2 2
MIRT661800 NUP85 nucleoporin 85 2 2
MIRT661853 ZNF766 zinc finger protein 766 2 2
MIRT662133 ZC3H8 zinc finger CCCH-type containing 8 2 2
MIRT662285 SLC29A4 solute carrier family 29 member 4 2 2
MIRT662705 C10orf111 chromosome 10 open reading frame 111 2 4
MIRT662823 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT662880 PCDHA6 protocadherin alpha 6 2 2
MIRT662999 TMEM59 transmembrane protein 59 2 2
MIRT663236 MPHOSPH8 M-phase phosphoprotein 8 2 2
MIRT663423 ZNF607 zinc finger protein 607 2 2
MIRT663696 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663832 AGBL5 ATP/GTP binding protein like 5 2 4
MIRT663858 MUC20 mucin 20, cell surface associated 2 2
MIRT664258 NMUR1 neuromedin U receptor 1 2 2
MIRT664842 HUS1 HUS1 checkpoint clamp component 2 2
MIRT664881 PRRG4 proline rich and Gla domain 4 2 2
MIRT664937 CARD6 caspase recruitment domain family member 6 2 4
MIRT665505 UTP15 UTP15, small subunit processome component 2 2
MIRT665640 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT665658 TRAF1 TNF receptor associated factor 1 2 2
MIRT665681 TNPO3 transportin 3 2 2
MIRT665934 TBC1D19 TBC1 domain family member 19 2 4
MIRT665995 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT666164 SNX27 sorting nexin family member 27 2 4
MIRT666364 SHOX short stature homeobox 2 2
MIRT666991 PDPN podoplanin 2 4
MIRT667179 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT667594 LIPC lipase C, hepatic type 2 2
MIRT667818 IRGQ immunity related GTPase Q 2 2
MIRT667845 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668571 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 4
MIRT669096 CDK19 cyclin dependent kinase 19 2 2
MIRT670062 ZNF783 zinc finger family member 783 2 2
MIRT670954 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT671180 ZNF891 zinc finger protein 891 2 2
MIRT673440 ZNF583 zinc finger protein 583 2 2
MIRT673941 ZNF500 zinc finger protein 500 2 2
MIRT674159 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674200 FUT2 fucosyltransferase 2 2 2
MIRT674677 PLCE1 phospholipase C epsilon 1 2 2
MIRT675232 MAK male germ cell associated kinase 2 2
MIRT676003 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT679836 GPR75 G protein-coupled receptor 75 2 2
MIRT680570 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT680750 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT680957 SLC15A1 solute carrier family 15 member 1 2 4
MIRT681201 ZNF638 zinc finger protein 638 2 2
MIRT681421 GTF3C6 general transcription factor IIIC subunit 6 2 2
MIRT681590 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT682026 AGXT2 alanine--glyoxylate aminotransferase 2 2 4
MIRT682340 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 4
MIRT682657 CASP8 caspase 8 2 2
MIRT682980 ABCA2 ATP binding cassette subfamily A member 2 2 2
MIRT683272 ZNF99 zinc finger protein 99 2 2
MIRT683349 SCARF1 scavenger receptor class F member 1 2 2
MIRT683447 ACOT2 acyl-CoA thioesterase 2 2 2
MIRT683586 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT683654 ZNF695 zinc finger protein 695 2 2
MIRT683733 EIF3L eukaryotic translation initiation factor 3 subunit L 2 2
MIRT683762 CPE carboxypeptidase E 2 2
MIRT683797 NOTO notochord homeobox 2 2
MIRT684453 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684510 C1orf174 chromosome 1 open reading frame 174 2 2
MIRT684979 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685003 CXorf56 chromosome X open reading frame 56 2 2
MIRT685106 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685123 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT685463 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT686021 UMPS uridine monophosphate synthetase 2 2
MIRT686551 TPM3 tropomyosin 3 2 2
MIRT686869 SLC25A32 solute carrier family 25 member 32 2 2
MIRT686962 SFT2D2 SFT2 domain containing 2 2 2
MIRT687278 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT688075 GLUL glutamate-ammonia ligase 2 2
MIRT688158 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT688574 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT688591 CYCS cytochrome c, somatic 2 2
MIRT689274 C5AR2 complement component 5a receptor 2 2 2
MIRT689427 CYB561 cytochrome b561 2 2
MIRT690043 C6orf141 chromosome 6 open reading frame 141 2 2
MIRT690214 C5orf45 MRN complex interacting protein 2 2
MIRT690259 CAMLG calcium modulating ligand 2 2
MIRT690319 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT690358 RPL37A ribosomal protein L37a 2 2
MIRT690519 ZNF566 zinc finger protein 566 2 2
MIRT690572 MICA MHC class I polypeptide-related sequence A 2 2
MIRT690707 WDR73 WD repeat domain 73 2 2
MIRT690862 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691150 APOL6 apolipoprotein L6 2 2
MIRT691279 CENPM centromere protein M 2 2
MIRT691754 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT691762 BCL2L15 BCL2 like 15 2 2
MIRT691775 SLC24A4 solute carrier family 24 member 4 2 2
MIRT692038 PAK1IP1 PAK1 interacting protein 1 2 2
MIRT692185 POLR1E RNA polymerase I subunit E 2 2
MIRT692756 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT692847 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT693064 AS3MT arsenite methyltransferase 2 2
MIRT693114 SCNM1 sodium channel modifier 1 2 2
MIRT693173 NPR1 natriuretic peptide receptor 1 2 2
MIRT693499 MOB3A MOB kinase activator 3A 2 2
MIRT693682 MXRA7 matrix remodeling associated 7 2 2
MIRT694066 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT694154 SLC36A2 solute carrier family 36 member 2 2 2
MIRT694251 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT694545 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694770 BVES blood vessel epicardial substance 2 2
MIRT695037 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT695265 CD209 CD209 molecule 2 2
MIRT695427 TCF23 transcription factor 23 2 2
MIRT695564 ZNF562 zinc finger protein 562 2 2
MIRT696357 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT696523 C3 complement C3 2 2
MIRT696611 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT696768 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT697066 PSMC4 proteasome 26S subunit, ATPase 4 2 2
MIRT697097 GPKOW G-patch domain and KOW motifs 2 2
MIRT697481 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT697622 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT697904 RPS27A ribosomal protein S27a 2 2
MIRT697956 TSPYL1 TSPY like 1 2 2
MIRT698366 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT698403 TM9SF3 transmembrane 9 superfamily member 3 2 2
MIRT698631 TES testin LIM domain protein 2 2
MIRT698963 SPAST spastin 2 2
MIRT699035 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699485 SLC10A6 solute carrier family 10 member 6 2 2
MIRT699579 SIKE1 suppressor of IKBKE 1 2 2
MIRT699594 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT699830 SCD stearoyl-CoA desaturase 2 2
MIRT700426 QDPR quinoid dihydropteridine reductase 2 2
MIRT700469 PURB purine rich element binding protein B 2 2
MIRT700863 PER2 period circadian clock 2 2 2
MIRT700943 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT701161 PACS2 phosphofurin acidic cluster sorting protein 2 2 2
MIRT701417 NHLRC2 NHL repeat containing 2 2 2
MIRT701468 NEK9 NIMA related kinase 9 2 2
MIRT701655 MYH9 myosin heavy chain 9 2 2
MIRT701693 MYADM myeloid associated differentiation marker 2 2
MIRT701769 MSL2 MSL complex subunit 2 2 2
MIRT701788 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT702784 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT703120 GPRC5A G protein-coupled receptor class C group 5 member A 2 2
MIRT703248 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT703265 GNL3L G protein nucleolar 3 like 2 2
MIRT703326 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT703648 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT703753 FAM118A family with sequence similarity 118 member A 2 2
MIRT703854 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT704315 DCUN1D5 defective in cullin neddylation 1 domain containing 5 2 2
MIRT704800 CDC73 cell division cycle 73 2 2
MIRT704941 CCDC120 coiled-coil domain containing 120 2 2
MIRT704975 CAV1 caveolin 1 2 2
MIRT705613 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 2
MIRT705672 ANKRD40 ankyrin repeat domain 40 2 2
MIRT706160 TFDP2 transcription factor Dp-2 2 2
MIRT706229 SYT15 synaptotagmin 15 2 2
MIRT706457 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT706555 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT707158 SMIM19 small integral membrane protein 19 2 2
MIRT710604 ZNF555 zinc finger protein 555 2 2
MIRT711709 IREB2 iron responsive element binding protein 2 2 2
MIRT711859 TRAF2 TNF receptor associated factor 2 2 2
MIRT713155 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT717108 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT721309 FAM58A cyclin Q 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4722 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4722 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4722 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4722-5p Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-4722-5p Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-4722-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4722-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4722-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

Error report submission