miRTarBase - #MIRT443585


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pre-miRNA Information
pre-miRNA hsa-mir-125b-2   
Genomic Coordinates chr21: 16590237 - 16590325
Synonyms MIRN125B2, MIR125B2
Description Homo sapiens miR-125b-2 stem-loop
Comment This miRNA sequence is predicted based on homology to a verified miRNA from mouse .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-125b-2-3p
Sequence 54| UCACAAGUCAGGCUCUUGGGAC |75
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 21 + 16590292 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs575583557 6 dbSNP
rs1331783293 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol FAM84B   
Synonyms BCMP101, NSE2
Description family with sequence similarity 84 member B
Transcript NM_174911   
Expression
Putative miRNA Targets on FAM84B
3'UTR of FAM84B
(miRNA target sites are highlighted)		 
>FAM84B|NM_174911|3'UTR
   1 TGGGCGAGCTGAGCGCAGAGCTGCGAAGGGGAACTGTTTGCAGTAGCAGCCGCTGCTCCCTTTCTCCCTCTCTTCCTCCC
  81 TCTTTTGCCACTGTCTGGGCCCCATCTGGGATTCCTGGGCCCTTTGGAAAAGAGTTGGTGAAATGCGCAGCCGGCTGTGG
 161 ACGGGGGAGGAGGAAGGGGACAGAGGGAGCAGGTAGGAAACACTTTAGTTGGGGGTGGGGGGCGTCTCCCTCTGGCCCCC
 241 TGTCTGTCTTCCTCTCCGCGGTGGAGCAAACTGTGGACTTGCCTGGCACTTAAACCTTGGTAGATCTGGGTTTATAATCG
 321 GCCATTCTTAAGCACGTGGGGTTGGGGGAAAGTTCGGAGTACCCATTCCTGCCGTTGCTTCCTATCCTGGGCTTGGAAGA
 401 ATCCTGGTAGAAAGGCCAGAGTGGGTTTGTGGAGTCGCCACTGCGGGACCAGCACGAAAGCTGCTTGTCTGCTTTGGCGG
 481 AGCTGAGCTGTGTATGGGATCCAGGAGGCTGGGGTGATTTATTTTATGGGATTCCTGGAGCGCAGGGCTGGTGAATCCAT
 561 GACAAGGTCCGGGAGCAGCAGACCAAAACCACAGCAGCCTCCTATTAAGTGTAACAAATAGTTAAGCAAACTCGGGCTAC
 641 AAACAAAGACTTTGCTACCTCCCTCCTCCACAACCCCCAAGTAATTAGCCTTCTGGAGCTGGCTCTTAGCTGAGGCTCCT
 721 GCTACCTCCTGCTCCACCCGCCCCTTCCTAGGTTACAAGTAAATCATTGTCAAGGGCCAGCCAGGGGAAGGTTTCAATTA
 801 AGGTTCTGTTCTGCTGCCTTTGTTTCTCCCCTGCTGTTGTAGGCACTTACAGCTGCGTTGTTATGAAAGGAGGGAATAGC
 881 CCTTTGTGTCTTTGATCTAATTAAACCTGCTTGGCTGTGTTTATCCGCAGGGCAGGTCACAGATAGGGTTGGCTGTGCCA
 961 CTCCATAAAGTATCTATTGTGGAAGCAGCCAAAAAGGGCTGCTGTGGCAGGAATTGGTTAATTTCTCCTTCCACTTCCCT
1041 TCCTGAATAGTGAAGGGAGCCCTTTTAAAACAAGGCTTTGGTGGTAATCCTGTGATTTTTTTTTCTCCCCCATCCCCTCA
1121 CTGGCCCATCCCTCTCACCCTCACTTTTGTTCTGCTGGTGGGTAAAATCTTAGGCTGAACACATATTTCAATGGTAAGAT
1201 ACTTATTTTGCTATCCACACTTGATGCAATTGAATTCAAGGTGCAAAGTCTTGTACTGAAGCAGTCTCCTTGTTGCTTGG
1281 AGAACACCTCCTTCAGAGCCCTTTGTTAAATAAGAGGGGCGACGTTGATCATAGATGCCACCTGGTTAGCACCGAATCTG
1361 ACTTTGGTGACAGTCCTAAAGCACAGTTGGTGATTGTGAGATCTGTTAGCGGCAGGCTGAGCAGATACTACTTGGTTTTG
1441 CTTGGTATGAGATACTACTGTTTGCTTAGTATGAGATTTTTTCCAGCCTGTCTCTTAAACTCCTGTGACATCTTCAATGA
1521 TATGTGCCCTCAGTTGCAGCATAGCTTCTCTGCTGCCTATTGCCATTGCTGTCTCAAAAGTTGAGTGAATTTTGAGGCGT
1601 CTTTTTTTTTTTTTCCTCTCTTGGGAGTCGTTGTAAACTACTGTGTACAAGTCATTTTGTGATATGATTCTGAACAGTTG
1681 GAATAGAATCATAGTTAAGTGGTACAGCCATGGCTATCGTCAGGCCTGTTGCCTGGAGATCTCTAAGTTAAGGCAACAAG
1761 ACTTAAAGAATTTTCTAATACACTTGTTTCACACATGGACGTTGAGGCCATAGTCTTTAAAAGCTTGGACCTTTGTAGCA
1841 CCTCAACATGAAAGGGCATTAGCTATGTTTCCTGTTTTTACAGTGATCACCAAACAGATCTTGCCACTTTGATTGTTAAA
1921 AATGAACCACATTCTAGCCCTGGTCTGGGACTTTGGAGGGAGATGAATTTCTTGTTGGAAATGTAAATCTAGTGTCCATA
2001 TTTAATACTCTCACAGCTTTGTGTTTATTCTCTTTGCTCATGGAATAGCAGAACAAGATAAACATGGGTTAAGACATTTA
2081 GGAGAACCTGCTGTATCTAACCCAGTTGGATTTTCTTTCATGCTTAACACAGTAGTGAAAATAGAAGGTAGGCCGGGCAC
2161 AGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTAGATCACCTGAAGTTAGGAGTTCGAGACCAGCC
2241 TGGCCAACATGGCGAAACCCTGTCTCTACCACAAATACAGAAAATTAGCTGGGCGTGGTGGCAGGCGCCTGTAATGCCTG
2321 CTACTTGGGAGCCTGAGGCAGAAGAATTGCTTGAAGCTGGGAAGCAGAGGTTGCAGTGAGCCGAGATCGCACCACTGCAC
2401 TCCAGCCTGGGCAGCAGAGCAAGTAGTAATAACCACCGTGTAGACAAGTGGGAGGGAAGAATAGAATGGCACTGTCCAGC
2481 TCTGGGCTAGCCAGATCAACTCCCCCACCCGTCTTCTTCCTCTGTCCCAGAATGGAAAATGATGTATGGTCAGTCACGCT
2561 GAAGTATAGCAGCGACTGTGTTAAGAGAGAGCAGTGACTCTCTCTTCTAGAGAAGAGGTTTTCAATAACAGGGCTTGGAA
2641 ATGAACTAGAATAGGAAATAGATCTTTTCAGATGCTGCTTTCCCATGTAATACAAGCGTTTCTACAGGGTACCAGAGGTG
2721 TGAAATATGTGACACTTAAGAACAGTGATTTTTATTGGGAATTTTCTTAGGGTTATTACACTTAAAGCAACAACCAACTA
2801 GTAACAGCTCCAGGAAAGGGGAATGAATCAACTCTTGGTTCTTTCCTGAAGACGGCAGTGTTGTGGATAAGTGAGTTTTT
2881 AATGCCCTGGCAGTGGCTACATTTGACACTTTAGAAAAAATAAACATATTTAATAATTTTTGTTTCTCCTTAGGAATAAG
2961 ACTGTAGAACTGTTTTGTACTGTGAATTACGGATGCTCTTTGAAGGAAAGAAATATCGATTCTAATGTTCTTCAGAAGTT
3041 CTGGCAGGGATAAGCAGGACATCGACTGGAACGTATGCTAAATGAAAGCAGACAAATTTCTATTTTCTTACCTGAGCAAA
3121 TATTTTATTGAAACTGCTTATGTATGTCAAAGGAGCCCACAACTTCAGCTACACAACTTTTTGTATTGAAAGAACTCATA
3201 CTTTTTGTAGCTTTTATTTCACATTTAATTTAAAGTGACTTTTAGCACTAAAATGCCTAGAAGATTTTACTCCAGACCTA
3281 TAAGGAAATGTTTAGTTTTTATGAAAAATGACAAGTCGATGGTTAAACTTCTCATGTCTTTGGTGCTTTGGCCCTAATAG
3361 CACTGGACAACACCACGACCACATGGAAACATATTTTTGGAAGCAAAACTTTAATTTTATATAACGTATGCTATGGAGAG
3441 CTAAGACAATTTAAGGACTACTTGTTTTCTATTTTTTTTCTTAATAAAATGGAATCCACTGTGTTGAAGACTCTTGATAT
3521 CATGTGCTTGTCTAACCATTTTTTGTTTTATAAATTAGAATAAAATATAGTTGTGATAATGGTCATCGAATGGATTTGTT
3601 TGGAAAGCTACATCTTATTTGTGAAATGTTTTTTAAATCAGAGTAACTATCAACTGATTCAGCTTTTTGTTGTTTTGTTC
3681 TTGGCTATAATACTTGTGACTCATGAAGAATTATGTTGACAAACAGGATAAATTCCACATGCATTTTATTTCCCAGTGAG
3761 TTGTATAAACTTTATTTTTGTTGAAGGTTGTATGTTAAATCAATGTTACATTCTTATATCACTTCTTGAGAAGGAAGTTC
3841 CGATTTGAAATTGTATCATTTCCTTCAAAATGAAGGGCAGTGCTTAGTTAAATAAAAGATTGATGATATCTTTTAAGCCA
3921 TTTCCTCTTCACTATGTCTTATTAAAATAAAACCTGTCAAGTTCTTTTCAAAAGATGCTATGAGCGTTTCCAATAAACCA
4001 TCTATTAGAGTTCACTGGAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' caggguucucggacUGAACACu 5'
                        ||||||| 
Target 5' ttcttggctataatACTTGTGa 3'
 3678 - 3699 140.00 -10.14
2 
miRNA  3' caGGGUUCUCGGACUGAACAcu 5'
            :::||| | || ||||||  
Target 5' aaTTTAAG-GACT-ACTTGTtt 3'
 3448 - 3467 134.00 -8.90
3 
miRNA  3' caggGUUCUCGGACUGAACACu 5'
              | | | :|| |:||||| 
Target 5' aaagCTACA-TCTTATTTGTGa 3'
 3604 - 3624 133.00 -9.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31577991 13 COSMIC
COSN23017162 59 COSMIC
COSN20066986 73 COSMIC
COSN31584417 73 COSMIC
COSN15661415 81 COSMIC
COSN16399505 297 COSMIC
COSN31538751 483 COSMIC
COSN31514981 544 COSMIC
COSN26585295 590 COSMIC
COSN26555760 729 COSMIC
COSN31486775 798 COSMIC
COSN24809315 840 COSMIC
COSN31565527 1008 COSMIC
COSN31570717 1025 COSMIC
COSN19526023 1087 COSMIC
COSN14705929 1268 COSMIC
COSN22367313 1354 COSMIC
COSN20105884 1602 COSMIC
COSN20935031 1745 COSMIC
COSN22892748 1764 COSMIC
COSN2259979 2445 COSMIC
COSN9255117 2473 COSMIC
COSN27515070 2599 COSMIC
COSN28251304 2770 COSMIC
COSN15660668 2851 COSMIC
COSN6911473 2857 COSMIC
COSN31532700 2927 COSMIC
COSN31530368 2940 COSMIC
COSN20770080 2963 COSMIC
COSN31589101 2990 COSMIC
COSN30167017 3073 COSMIC
COSN31547522 3138 COSMIC
COSN17272566 3196 COSMIC
COSN24624060 3221 COSMIC
COSN30173378 3425 COSMIC
COSN26548844 3518 COSMIC
COSN31607220 3666 COSMIC
COSN21506926 3703 COSMIC
COSN19514703 3717 COSMIC
COSN31555017 3731 COSMIC
COSN31527921 3774 COSMIC
COSN23836268 3803 COSMIC
COSN21288451 3850 COSMIC
COSN31589108 4008 COSMIC
COSN26564717 4013 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1375931755 2 dbSNP
rs1172943061 3 dbSNP
rs376896029 4 dbSNP
rs752454857 7 dbSNP
rs765038660 8 dbSNP
rs1428107013 9 dbSNP
rs1261341023 10 dbSNP
rs1190092728 15 dbSNP
rs1002534720 16 dbSNP
rs759408368 23 dbSNP
rs1403857025 24 dbSNP
rs1451560756 25 dbSNP
rs1209345375 26 dbSNP
rs753887875 28 dbSNP
rs905002970 29 dbSNP
rs1313174448 30 dbSNP
rs1252224861 31 dbSNP
rs760305312 39 dbSNP
rs1325440972 40 dbSNP
rs1275929091 44 dbSNP
rs1416021128 48 dbSNP
rs772826880 51 dbSNP
rs1379277744 58 dbSNP
rs1278038678 66 dbSNP
rs562469733 70 dbSNP
rs1395447295 76 dbSNP
rs1209478919 82 dbSNP
rs1270509952 83 dbSNP
rs1200447998 87 dbSNP
rs951435524 87 dbSNP
rs2305976 91 dbSNP
rs559235209 92 dbSNP
rs1304461585 101 dbSNP
rs1025730288 107 dbSNP
rs1179199180 117 dbSNP
rs1410799207 128 dbSNP
rs543054768 145 dbSNP
rs1005247000 146 dbSNP
rs1037580489 147 dbSNP
rs1465470193 152 dbSNP
rs112715226 153 dbSNP
rs1046714857 157 dbSNP
rs770776953 161 dbSNP
rs1421118381 163 dbSNP
rs573985144 164 dbSNP
rs554077956 179 dbSNP
rs1290279817 182 dbSNP
rs1321585350 192 dbSNP
rs1057408215 196 dbSNP
rs1186219007 200 dbSNP
rs772490463 207 dbSNP
rs933706731 209 dbSNP
rs1250527286 211 dbSNP
rs922270626 212 dbSNP
rs1041474658 217 dbSNP
rs914319549 223 dbSNP
rs947172308 223 dbSNP
rs975575987 224 dbSNP
rs73335142 225 dbSNP
rs1262891172 228 dbSNP
rs1167744560 229 dbSNP
rs1371003891 236 dbSNP
rs942962688 241 dbSNP
rs1310133367 250 dbSNP
rs1214767830 256 dbSNP
rs192737452 257 dbSNP
rs1302537430 260 dbSNP
rs1356113094 264 dbSNP
rs926079766 267 dbSNP
rs534375759 281 dbSNP
rs1343398790 286 dbSNP
rs1261451864 290 dbSNP
rs951422094 292 dbSNP
rs1244181050 296 dbSNP
rs967436456 297 dbSNP
rs1319936593 299 dbSNP
rs913358415 314 dbSNP
rs992819308 319 dbSNP
rs995506438 321 dbSNP
rs1426653457 324 dbSNP
rs1187926306 325 dbSNP
rs749069517 336 dbSNP
rs1431454100 341 dbSNP
rs1170666234 346 dbSNP
rs143813213 348 dbSNP
rs1296083829 350 dbSNP
rs1294209294 357 dbSNP
rs1369892940 364 dbSNP
rs1002100164 368 dbSNP
rs1360782190 370 dbSNP
rs558344219 372 dbSNP
rs1231100723 373 dbSNP
rs1455960157 375 dbSNP
rs1289086705 393 dbSNP
rs1369639419 396 dbSNP
rs1221927507 402 dbSNP
rs36109779 405 dbSNP
rs753172232 415 dbSNP
rs370393509 418 dbSNP
rs1003169278 425 dbSNP
rs548920238 433 dbSNP
rs748176702 434 dbSNP
rs1191933763 440 dbSNP
rs1489444479 445 dbSNP
rs1248593419 448 dbSNP
rs1451055167 451 dbSNP
rs1262706701 452 dbSNP
rs1411823794 453 dbSNP
rs1423448508 455 dbSNP
rs1005382963 463 dbSNP
rs1351657233 468 dbSNP
rs886854229 479 dbSNP
rs947034864 480 dbSNP
rs1282779346 481 dbSNP
rs1378991538 487 dbSNP
rs980479628 492 dbSNP
rs1267281065 494 dbSNP
rs1314564957 498 dbSNP
rs914352062 508 dbSNP
rs1268612592 512 dbSNP
rs1233869176 513 dbSNP
rs1317219770 514 dbSNP
rs1201758695 515 dbSNP
rs1236675872 515 dbSNP
rs1483476591 525 dbSNP
rs1182641708 527 dbSNP
rs1416254899 538 dbSNP
rs1276133970 542 dbSNP
rs1471626694 544 dbSNP
rs1158521771 547 dbSNP
rs1413263669 554 dbSNP
rs569737072 557 dbSNP
rs6982970 564 dbSNP
rs912687777 567 dbSNP
rs1322498467 570 dbSNP
rs986980766 571 dbSNP
rs754399946 576 dbSNP
rs900810876 578 dbSNP
rs536296869 579 dbSNP
rs748583638 580 dbSNP
rs1293597997 583 dbSNP
rs1217374762 584 dbSNP
rs942950389 587 dbSNP
rs1312504017 600 dbSNP
rs567551805 601 dbSNP
rs770109848 603 dbSNP
rs1212010169 604 dbSNP
rs904799675 606 dbSNP
rs1239359260 609 dbSNP
rs547742070 612 dbSNP
rs1233053506 618 dbSNP
rs1043243821 631 dbSNP
rs946229501 633 dbSNP
rs913410143 639 dbSNP
rs1473643317 641 dbSNP
rs1425124002 648 dbSNP
rs1479026810 648 dbSNP
rs1415337304 649 dbSNP
rs992903939 650 dbSNP
rs1369158434 658 dbSNP
rs1373948315 661 dbSNP
rs1408834191 663 dbSNP
rs938778751 664 dbSNP
rs927303586 665 dbSNP
rs534102421 666 dbSNP
rs1351771641 673 dbSNP
rs1433700767 674 dbSNP
rs149018753 675 dbSNP
rs1345630742 683 dbSNP
rs1220676882 687 dbSNP
rs551554612 695 dbSNP
rs1016842465 696 dbSNP
rs1204678829 698 dbSNP
rs958570933 700 dbSNP
rs1196853416 705 dbSNP
rs1214385267 705 dbSNP
rs1246578367 708 dbSNP
rs1457321356 709 dbSNP
rs1478635916 719 dbSNP
rs1256112245 724 dbSNP
rs970097548 736 dbSNP
rs1388675010 738 dbSNP
rs984012026 739 dbSNP
rs1429565910 740 dbSNP
rs755031040 740 dbSNP
rs1168783716 741 dbSNP
rs1372052335 751 dbSNP
rs531708230 755 dbSNP
rs563039472 760 dbSNP
rs900945089 763 dbSNP
rs548950236 766 dbSNP
rs1230687578 774 dbSNP
rs1011209218 778 dbSNP
rs529273979 789 dbSNP
rs761483106 791 dbSNP
rs779516137 797 dbSNP
rs1208347253 808 dbSNP
rs566599176 808 dbSNP
rs751597780 815 dbSNP
rs1329940631 818 dbSNP
rs544162988 824 dbSNP
rs780574513 825 dbSNP
rs1397711927 826 dbSNP
rs867718723 829 dbSNP
rs1051727881 831 dbSNP
rs75739669 832 dbSNP
rs918850015 833 dbSNP
rs1189613343 836 dbSNP
rs1057491245 843 dbSNP
rs1464785552 849 dbSNP
rs750759906 860 dbSNP
rs1471595965 862 dbSNP
rs1162349672 863 dbSNP
rs927409603 872 dbSNP
rs974300227 873 dbSNP
rs980121723 874 dbSNP
rs1318417702 878 dbSNP
rs1387825211 880 dbSNP
rs1435471914 883 dbSNP
rs1379601636 885 dbSNP
rs560010680 889 dbSNP
rs1338554253 909 dbSNP
rs1194460150 923 dbSNP
rs1242839957 926 dbSNP
rs1361177942 927 dbSNP
rs540489385 928 dbSNP
rs1357084306 932 dbSNP
rs1235248960 933 dbSNP
rs990809623 934 dbSNP
rs961114353 935 dbSNP
rs536270412 948 dbSNP
rs1438316844 952 dbSNP
rs1277722317 956 dbSNP
rs1441100546 965 dbSNP
rs1186343323 970 dbSNP
rs981709388 972 dbSNP
rs749899340 976 dbSNP
rs139351237 988 dbSNP
rs967208897 992 dbSNP
rs1457701749 1008 dbSNP
rs1280641377 1009 dbSNP
rs1020176763 1010 dbSNP
rs909220722 1011 dbSNP
rs1024620519 1012 dbSNP
rs564477960 1017 dbSNP
rs951311942 1027 dbSNP
rs1341300863 1049 dbSNP
rs568719705 1056 dbSNP
rs1286512645 1062 dbSNP
rs760314173 1063 dbSNP
rs1025461943 1075 dbSNP
rs1336857996 1099 dbSNP
rs1017935732 1105 dbSNP
rs1263042686 1105 dbSNP
rs1287444954 1105 dbSNP
rs397690224 1105 dbSNP
rs60722538 1105 dbSNP
rs1334019639 1117 dbSNP
rs1006540182 1121 dbSNP
rs977012946 1129 dbSNP
rs1050838840 1130 dbSNP
rs1161135741 1131 dbSNP
rs930157519 1132 dbSNP
rs1159498577 1137 dbSNP
rs1465300025 1138 dbSNP
rs187849899 1140 dbSNP
rs1404151421 1146 dbSNP
rs1436809203 1148 dbSNP
rs1419293697 1155 dbSNP
rs1349898859 1156 dbSNP
rs1018474673 1157 dbSNP
rs1378616091 1158 dbSNP
rs372455045 1161 dbSNP
rs1038639053 1168 dbSNP
rs1160515558 1169 dbSNP
rs9643213 1173 dbSNP
rs941625257 1182 dbSNP
rs1393394742 1183 dbSNP
rs1233233368 1185 dbSNP
rs576047324 1191 dbSNP
rs1350556644 1195 dbSNP
rs1236835697 1201 dbSNP
rs1185284152 1204 dbSNP
rs1202562165 1206 dbSNP
rs968333327 1207 dbSNP
rs1443955112 1209 dbSNP
rs556257912 1213 dbSNP
rs1010480782 1216 dbSNP
rs939353930 1219 dbSNP
rs892076185 1224 dbSNP
rs780866017 1231 dbSNP
rs1003489209 1233 dbSNP
rs878960780 1237 dbSNP
rs1265107583 1246 dbSNP
rs752400787 1247 dbSNP
rs906042432 1252 dbSNP
rs767087432 1263 dbSNP
rs1396626770 1266 dbSNP
rs1427633064 1267 dbSNP
rs184063989 1278 dbSNP
rs1223866500 1280 dbSNP
rs928052006 1291 dbSNP
rs1284146719 1293 dbSNP
rs759017088 1294 dbSNP
rs1299958156 1295 dbSNP
rs1388753482 1296 dbSNP
rs773764496 1319 dbSNP
rs770853030 1320 dbSNP
rs1357801245 1323 dbSNP
rs146675216 1324 dbSNP
rs929874343 1325 dbSNP
rs1226686550 1335 dbSNP
rs918535977 1338 dbSNP
rs191791828 1342 dbSNP
rs1342447628 1345 dbSNP
rs1358874587 1353 dbSNP
rs534040167 1354 dbSNP
rs1401395326 1357 dbSNP
rs965551909 1361 dbSNP
rs911060277 1362 dbSNP
rs913101239 1367 dbSNP
rs1254852352 1374 dbSNP
rs1447368023 1390 dbSNP
rs187313201 1391 dbSNP
rs1390624066 1393 dbSNP
rs1489491786 1396 dbSNP
rs989940683 1400 dbSNP
rs1172859982 1402 dbSNP
rs183025228 1410 dbSNP
rs1021281837 1411 dbSNP
rs1397329039 1412 dbSNP
rs538075498 1414 dbSNP
rs1314944462 1417 dbSNP
rs569227630 1427 dbSNP
rs1433274222 1438 dbSNP
rs1487153146 1446 dbSNP
rs1006983261 1454 dbSNP
rs1264887671 1460 dbSNP
rs878901086 1471 dbSNP
rs1450589423 1483 dbSNP
rs1215925873 1484 dbSNP
rs1310198255 1487 dbSNP
rs1320537097 1492 dbSNP
rs1287091139 1500 dbSNP
rs756906569 1505 dbSNP
rs370661467 1508 dbSNP
rs1463482126 1510 dbSNP
rs1337564377 1511 dbSNP
rs993895172 1518 dbSNP
rs896898057 1520 dbSNP
rs1038586323 1528 dbSNP
rs1411936903 1536 dbSNP
rs1005704049 1537 dbSNP
rs1218411112 1546 dbSNP
rs1165764909 1551 dbSNP
rs773137803 1555 dbSNP
rs1055353255 1570 dbSNP
rs549038110 1571 dbSNP
rs939366625 1580 dbSNP
rs927947640 1581 dbSNP
rs1272170783 1582 dbSNP
rs1378012432 1583 dbSNP
rs1003130649 1595 dbSNP
rs147791258 1598 dbSNP
rs1349414896 1599 dbSNP
rs945520647 1601 dbSNP
rs1318464581 1608 dbSNP
rs1207762047 1609 dbSNP
rs906004702 1611 dbSNP
rs1483040156 1612 dbSNP
rs1189002770 1614 dbSNP
rs1259663400 1615 dbSNP
rs1402746738 1615 dbSNP
rs1409391285 1615 dbSNP
rs1471677355 1615 dbSNP
rs58174190 1615 dbSNP
rs796081134 1615 dbSNP
rs1174384909 1616 dbSNP
rs1359018791 1617 dbSNP
rs1395144699 1617 dbSNP
rs1434921804 1623 dbSNP
rs1314382251 1624 dbSNP
rs1348037442 1625 dbSNP
rs1279997894 1627 dbSNP
rs1408724545 1627 dbSNP
rs1169790721 1635 dbSNP
rs1217461924 1642 dbSNP
rs1277650106 1643 dbSNP
rs1348369149 1644 dbSNP
rs1044584153 1645 dbSNP
rs989971836 1647 dbSNP
rs1282762594 1651 dbSNP
rs571511289 1653 dbSNP
rs1209766743 1659 dbSNP
rs1421359616 1664 dbSNP
rs1181572069 1665 dbSNP
rs772978722 1666 dbSNP
rs1471441485 1670 dbSNP
rs1186784098 1680 dbSNP
rs1190026300 1681 dbSNP
rs1424873734 1691 dbSNP
rs781501444 1692 dbSNP
rs1175084406 1696 dbSNP
rs1368322052 1697 dbSNP
rs1428475046 1702 dbSNP
rs1047717235 1710 dbSNP
rs929340960 1711 dbSNP
rs1355842553 1713 dbSNP
rs1223142209 1718 dbSNP
rs149700734 1719 dbSNP
rs1041320280 1725 dbSNP
rs1198520059 1740 dbSNP
rs1236257421 1744 dbSNP
rs1316499466 1748 dbSNP
rs943986939 1751 dbSNP
rs1215449739 1753 dbSNP
rs546590694 1756 dbSNP
rs911033431 1760 dbSNP
rs1029362170 1765 dbSNP
rs73705689 1768 dbSNP
rs1439688016 1777 dbSNP
rs1367156118 1781 dbSNP
rs985314961 1785 dbSNP
rs747066732 1786 dbSNP
rs1273244645 1793 dbSNP
rs1469134217 1801 dbSNP
rs111885486 1804 dbSNP
rs1371768334 1806 dbSNP
rs563903300 1824 dbSNP
rs1330646897 1830 dbSNP
rs988569136 1846 dbSNP
rs1168178950 1847 dbSNP
rs1345254232 1848 dbSNP
rs955860129 1856 dbSNP
rs1463972132 1859 dbSNP
rs1005735235 1865 dbSNP
rs191946946 1870 dbSNP
rs1170862648 1873 dbSNP
rs982074240 1875 dbSNP
rs1364248087 1884 dbSNP
rs780050667 1886 dbSNP
rs796501195 1891 dbSNP
rs1195064103 1895 dbSNP
rs1454348565 1896 dbSNP
rs1006382738 1903 dbSNP
rs1237013975 1915 dbSNP
rs1178614895 1916 dbSNP
rs887853792 1923 dbSNP
rs1055787766 1930 dbSNP
rs1253512964 1937 dbSNP
rs1003833608 1938 dbSNP
rs906776412 1939 dbSNP
rs1026321485 1949 dbSNP
rs1205679147 1958 dbSNP
rs1042415824 1974 dbSNP
rs575822932 1975 dbSNP
rs945367822 1979 dbSNP
rs1162141053 1983 dbSNP
rs1418035140 1991 dbSNP
rs562292183 1992 dbSNP
rs189055983 2001 dbSNP
rs1348739186 2005 dbSNP
rs1387573004 2010 dbSNP
rs74519505 2011 dbSNP
rs78338944 2012 dbSNP
rs935841212 2017 dbSNP
rs1446169340 2032 dbSNP
rs943935204 2034 dbSNP
rs889749263 2037 dbSNP
rs77693027 2039 dbSNP
rs933960659 2046 dbSNP
rs947170410 2054 dbSNP
rs528251767 2058 dbSNP
rs1175182404 2059 dbSNP
rs1306353160 2069 dbSNP
rs577841840 2071 dbSNP
rs972453224 2086 dbSNP
rs988537920 2092 dbSNP
rs934442418 2094 dbSNP
rs928278319 2106 dbSNP
rs1379228781 2117 dbSNP
rs1156294361 2120 dbSNP
rs1179880209 2121 dbSNP
rs1454072440 2131 dbSNP
rs558057541 2133 dbSNP
rs1420294521 2138 dbSNP
rs981152210 2142 dbSNP
rs1399880818 2149 dbSNP
rs537773060 2154 dbSNP
rs560226987 2155 dbSNP
rs1312547520 2157 dbSNP
rs1483141623 2160 dbSNP
rs1255809213 2162 dbSNP
rs1213373596 2167 dbSNP
rs568998971 2168 dbSNP
rs983833017 2169 dbSNP
rs985014064 2172 dbSNP
rs952173829 2175 dbSNP
rs555151405 2176 dbSNP
rs535508580 2180 dbSNP
rs1026459141 2182 dbSNP
rs959536015 2185 dbSNP
rs113444634 2191 dbSNP
rs1209647922 2194 dbSNP
rs1238059526 2201 dbSNP
rs182379185 2202 dbSNP
rs1318764101 2204 dbSNP
rs1280638045 2218 dbSNP
rs1307642728 2220 dbSNP
rs1227649589 2222 dbSNP
rs1376757399 2230 dbSNP
rs546580627 2231 dbSNP
rs901950583 2235 dbSNP
rs1183949887 2237 dbSNP
rs1359517030 2238 dbSNP
rs533399506 2241 dbSNP
rs762853345 2253 dbSNP
rs1007594273 2254 dbSNP
rs1363823633 2260 dbSNP
rs376415579 2261 dbSNP
rs906814444 2272 dbSNP
rs1160534446 2277 dbSNP
rs373267128 2280 dbSNP
rs1436594585 2291 dbSNP
rs889129598 2293 dbSNP
rs1306245042 2294 dbSNP
rs767156203 2295 dbSNP
rs1416216510 2300 dbSNP
rs191082844 2305 dbSNP
rs369787410 2306 dbSNP
rs1052971386 2307 dbSNP
rs934385778 2308 dbSNP
rs1303618191 2313 dbSNP
rs1053809337 2314 dbSNP
rs1349585964 2329 dbSNP
rs1225810556 2336 dbSNP
rs1250232735 2337 dbSNP
rs943493451 2341 dbSNP
rs1197430549 2344 dbSNP
rs889194787 2352 dbSNP
rs1049603999 2368 dbSNP
rs1203561603 2369 dbSNP
rs928441057 2373 dbSNP
rs981505114 2377 dbSNP
rs922557029 2382 dbSNP
rs1261356370 2383 dbSNP
rs531127877 2388 dbSNP
rs1372528545 2389 dbSNP
rs915579014 2390 dbSNP
rs1332577171 2395 dbSNP
rs1300349097 2396 dbSNP
rs1392942167 2402 dbSNP
rs984982646 2409 dbSNP
rs185431392 2437 dbSNP
rs919412492 2438 dbSNP
rs1294431508 2446 dbSNP
rs375451947 2448 dbSNP
rs1307522418 2458 dbSNP
rs542446479 2493 dbSNP
rs982317269 2499 dbSNP
rs1214315698 2502 dbSNP
rs1254626984 2506 dbSNP
rs1275939511 2507 dbSNP
rs1463396447 2508 dbSNP
rs1184962092 2509 dbSNP
rs528985353 2510 dbSNP
rs971281497 2511 dbSNP
rs1021211901 2520 dbSNP
rs1415860557 2522 dbSNP
rs117895554 2524 dbSNP
rs73705688 2529 dbSNP
rs1397075190 2543 dbSNP
rs894056663 2544 dbSNP
rs1392924417 2545 dbSNP
rs577535245 2553 dbSNP
rs557484518 2554 dbSNP
rs142690541 2557 dbSNP
rs373512434 2558 dbSNP
rs998047004 2561 dbSNP
rs111974236 2573 dbSNP
rs866380414 2574 dbSNP
rs1053357937 2583 dbSNP
rs1261157383 2587 dbSNP
rs1486316581 2587 dbSNP
rs1188549586 2588 dbSNP
rs998730969 2593 dbSNP
rs1255466024 2601 dbSNP
rs907036568 2602 dbSNP
rs1467144239 2606 dbSNP
rs1399258438 2607 dbSNP
rs1036957508 2609 dbSNP
rs1346226713 2618 dbSNP
rs1454992513 2623 dbSNP
rs773227750 2624 dbSNP
rs776634099 2632 dbSNP
rs1310720914 2633 dbSNP
rs939953951 2641 dbSNP
rs765273915 2649 dbSNP
rs139360235 2653 dbSNP
rs1294991227 2662 dbSNP
rs146276063 2671 dbSNP
rs566612101 2685 dbSNP
rs1317124994 2687 dbSNP
rs937645702 2690 dbSNP
rs926412834 2691 dbSNP
rs930894639 2697 dbSNP
rs982231495 2698 dbSNP
rs970929716 2711 dbSNP
rs771001582 2712 dbSNP
rs914107817 2717 dbSNP
rs1211697347 2726 dbSNP
rs143345010 2727 dbSNP
rs181210413 2732 dbSNP
rs1372473597 2735 dbSNP
rs1177174792 2738 dbSNP
rs1409145817 2743 dbSNP
rs1032541680 2745 dbSNP
rs966199229 2749 dbSNP
rs1374488482 2754 dbSNP
rs912066123 2755 dbSNP
rs1314176841 2760 dbSNP
rs1328572901 2772 dbSNP
rs1462395207 2781 dbSNP
rs1298703800 2805 dbSNP
rs1375200540 2810 dbSNP
rs1400114648 2813 dbSNP
rs1301443898 2825 dbSNP
rs763857238 2831 dbSNP
rs1347406765 2835 dbSNP
rs1235382076 2836 dbSNP
rs1280785614 2837 dbSNP
rs372179192 2838 dbSNP
rs570793679 2844 dbSNP
rs550709939 2849 dbSNP
rs562785889 2853 dbSNP
rs1463802885 2854 dbSNP
rs1373865430 2855 dbSNP
rs1030417230 2857 dbSNP
rs1394930587 2862 dbSNP
rs796706614 2885 dbSNP
rs1175180429 2888 dbSNP
rs997974484 2893 dbSNP
rs957264424 2899 dbSNP
rs950665099 2901 dbSNP
rs139933896 2908 dbSNP
rs190419066 2912 dbSNP
rs1254944150 2917 dbSNP
rs1438691403 2918 dbSNP
rs1194230610 2919 dbSNP
rs1324967499 2921 dbSNP
rs1457251756 2930 dbSNP
rs1004035986 2934 dbSNP
rs528722301 2942 dbSNP
rs1374855809 2948 dbSNP
rs1337457370 2953 dbSNP
rs1214079013 2957 dbSNP
rs1197341277 2963 dbSNP
rs144277710 2964 dbSNP
rs1255068932 2966 dbSNP
rs747232599 2969 dbSNP
rs775631459 2971 dbSNP
rs1231592239 2975 dbSNP
rs1469209648 2981 dbSNP
rs1195073995 2985 dbSNP
rs1240004231 2986 dbSNP
rs540289266 2990 dbSNP
rs894252999 2991 dbSNP
rs1421102143 2993 dbSNP
rs1459780580 2996 dbSNP
rs949194986 2997 dbSNP
rs1394882216 3009 dbSNP
rs186092609 3013 dbSNP
rs1442362090 3016 dbSNP
rs1048704456 3017 dbSNP
rs1335702814 3018 dbSNP
rs1324895766 3024 dbSNP
rs913638174 3026 dbSNP
rs1270817897 3033 dbSNP
rs1327366421 3044 dbSNP
rs879898996 3049 dbSNP
rs1414471911 3060 dbSNP
rs930278357 3063 dbSNP
rs772099431 3064 dbSNP
rs745956525 3072 dbSNP
rs1397599613 3081 dbSNP
rs944968584 3082 dbSNP
rs958172951 3089 dbSNP
rs1282663777 3096 dbSNP
rs912052241 3102 dbSNP
rs1193504430 3104 dbSNP
rs1264678773 3111 dbSNP
rs772295621 3126 dbSNP
rs75557922 3127 dbSNP
rs1397040845 3128 dbSNP
rs1187086327 3134 dbSNP
rs543916707 3139 dbSNP
rs1418505453 3152 dbSNP
rs757790568 3156 dbSNP
rs1156592633 3166 dbSNP
rs1384025343 3169 dbSNP
rs1400320829 3172 dbSNP
rs1174353015 3177 dbSNP
rs1439089076 3183 dbSNP
rs986749825 3183 dbSNP
rs1304751222 3186 dbSNP
rs575178845 3196 dbSNP
rs1413021312 3205 dbSNP
rs1293149405 3207 dbSNP
rs565554501 3211 dbSNP
rs915360674 3224 dbSNP
rs1183839401 3238 dbSNP
rs1278113476 3245 dbSNP
rs533744584 3246 dbSNP
rs555277916 3259 dbSNP
rs989570207 3266 dbSNP
rs1287757988 3272 dbSNP
rs956651386 3274 dbSNP
rs1255174230 3283 dbSNP
rs1466618791 3285 dbSNP
rs1031436711 3292 dbSNP
rs977335496 3302 dbSNP
rs541602803 3317 dbSNP
rs1024123045 3318 dbSNP
rs1362962833 3319 dbSNP
rs1012736926 3328 dbSNP
rs1159410092 3333 dbSNP
rs866323375 3358 dbSNP
rs1382412730 3369 dbSNP
rs181935525 3376 dbSNP
rs749605829 3377 dbSNP
rs888241230 3383 dbSNP
rs1280530921 3387 dbSNP
rs778047941 3390 dbSNP
rs1376181765 3395 dbSNP
rs1398281940 3399 dbSNP
rs1168976640 3406 dbSNP
rs1327460100 3419 dbSNP
rs1335505421 3420 dbSNP
rs1238802617 3422 dbSNP
rs1347876070 3424 dbSNP
rs1026909615 3425 dbSNP
rs16901511 3429 dbSNP
rs1280392417 3446 dbSNP
rs1483961679 3451 dbSNP
rs1193966541 3452 dbSNP
rs539884163 3457 dbSNP
rs1438131599 3471 dbSNP
rs1336767274 3472 dbSNP
rs1312649865 3473 dbSNP
rs1250976139 3475 dbSNP
rs1413257763 3476 dbSNP
rs1452773589 3478 dbSNP
rs905104353 3479 dbSNP
rs1378224641 3480 dbSNP
rs1467673728 3480 dbSNP
rs1046509037 3483 dbSNP
rs1166595848 3485 dbSNP
rs1396427314 3489 dbSNP
rs1392548091 3492 dbSNP
rs1333753123 3496 dbSNP
rs766070185 3500 dbSNP
rs897462244 3501 dbSNP
rs1439649010 3505 dbSNP
rs892230847 3507 dbSNP
rs1036468635 3513 dbSNP
rs757916008 3515 dbSNP
rs936846295 3516 dbSNP
rs138144332 3517 dbSNP
rs11539702 3518 dbSNP
rs1467884517 3521 dbSNP
rs1193196076 3523 dbSNP
rs1268322852 3526 dbSNP
rs932265905 3536 dbSNP
rs1191111604 3555 dbSNP
rs1372618831 3568 dbSNP
rs923529777 3587 dbSNP
rs976502883 3588 dbSNP
rs962014401 3602 dbSNP
rs554714906 3618 dbSNP
rs1293700256 3624 dbSNP
rs1050572682 3634 dbSNP
rs1380232742 3641 dbSNP
rs190225865 3643 dbSNP
rs952099633 3644 dbSNP
rs1484518209 3647 dbSNP
rs765220874 3649 dbSNP
rs749821060 3651 dbSNP
rs1215381591 3662 dbSNP
rs1271229790 3667 dbSNP
rs1333795786 3672 dbSNP
rs1214109998 3681 dbSNP
rs185754471 3687 dbSNP
rs1267054705 3689 dbSNP
rs1489571537 3698 dbSNP
rs867263824 3703 dbSNP
rs1203664553 3708 dbSNP
rs1261070999 3709 dbSNP
rs146635007 3718 dbSNP
rs1196390756 3729 dbSNP
rs1002023373 3739 dbSNP
rs989539265 3742 dbSNP
rs150811747 3758 dbSNP
rs1352016357 3761 dbSNP
rs923951117 3763 dbSNP
rs982543764 3770 dbSNP
rs1287943313 3774 dbSNP
rs1231875957 3787 dbSNP
rs892093461 3792 dbSNP
rs971336551 3793 dbSNP
rs1052145395 3803 dbSNP
rs936460176 3807 dbSNP
rs1294186827 3813 dbSNP
rs1228860051 3814 dbSNP
rs1314583581 3816 dbSNP
rs1024609222 3817 dbSNP
rs1237107472 3823 dbSNP
rs1430234940 3828 dbSNP
rs868337433 3828 dbSNP
rs1488627033 3836 dbSNP
rs1218876978 3837 dbSNP
rs143006902 3841 dbSNP
rs958509170 3842 dbSNP
rs1182998194 3844 dbSNP
rs1027458536 3846 dbSNP
rs189365099 3850 dbSNP
rs1157827385 3851 dbSNP
rs1380542079 3852 dbSNP
rs1421202015 3856 dbSNP
rs1310537766 3866 dbSNP
rs897594794 3869 dbSNP
rs1304548252 3877 dbSNP
rs1162656831 3889 dbSNP
rs1370826933 3891 dbSNP
rs368297695 3891 dbSNP
rs932140851 3898 dbSNP
rs1309788574 3906 dbSNP
rs1354683569 3908 dbSNP
rs1014591900 3910 dbSNP
rs1462842916 3919 dbSNP
rs1009016507 3920 dbSNP
rs1239727582 3924 dbSNP
rs923536099 3925 dbSNP
rs1239241298 3926 dbSNP
rs976320864 3927 dbSNP
rs1171388078 3930 dbSNP
rs890133097 3938 dbSNP
rs1414550371 3942 dbSNP
rs1178074797 3957 dbSNP
rs1418280477 3959 dbSNP
rs1192537522 3960 dbSNP
rs940679899 3964 dbSNP
rs1441476455 3972 dbSNP
rs1050626367 3975 dbSNP
rs1449208023 3977 dbSNP
rs776460347 3978 dbSNP
rs533043354 3984 dbSNP
rs893948816 3986 dbSNP
rs1053985750 3989 dbSNP
rs935410743 3993 dbSNP
rs924059618 4000 dbSNP
rs1046385374 4008 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000304916.3 | 3UTR | UUGGCUAUAAUACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE32688 Pancreatic cancer 0.432 6.8e-3 0.434 6.5e-3 32 Click to see details
GSE28260 Renal cortex and medulla 0.599 1.5e-2 0.588 1.7e-2 13 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.401 2.3e-2 -0.398 2.4e-2 25 Click to see details
GSE21687 Ependynoma primary tumors 0.24 2.8e-2 0.220 4.0e-2 64 Click to see details
GSE19536 Breast cancer -0.183 3.4e-2 -0.148 7.1e-2 100 Click to see details
GSE19783 ER- ER- breast cancer -0.112 1.6e-1 -0.104 1.8e-1 79 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.185 1.9e-1 0.312 6.4e-2 25 Click to see details
GSE19783 ER+ ER+ breast cancer -0.182 2.2e-1 -0.044 4.3e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.145 2.5e-1 -0.074 3.7e-1 24 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.678 2.6e-1 0.500 3.3e-1 3 Click to see details
GSE28544 Breast cancer 0.13 2.7e-1 0.129 2.7e-1 24 Click to see details
GSE42095 Differentiated embryonic stem cells 0.133 2.7e-1 -0.003 4.9e-1 23 Click to see details
GSE21032 Prostate cancer 0.065 2.8e-1 -0.115 1.5e-1 83 Click to see details
GSE19350 CNS germ cell tumors 0.178 2.9e-1 0.215 2.5e-1 12 Click to see details
GSE38226 Liver fibrosis -0.123 3.0e-1 0.098 3.4e-1 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.07 3.8e-1 0.217 1.8e-1 20 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.337 0.01 -0.308 0.02 49 Click to see details
KIRC 0.212 0.04 0.121 0.16 68 Click to see details
UCEC 0.356 0.07 0.461 0.02 19 Click to see details
PAAD 0.829 0.09 0.400 0.3 4 Click to see details
CHOL -0.495 0.09 -0.533 0.07 9 Click to see details
COAD -0.428 0.15 -0.405 0.16 8 Click to see details
PCPG 0.882 0.16 0.500 0.33 3 Click to see details
STAD -0.18 0.16 -0.107 0.28 32 Click to see details
LUAD -0.297 0.17 -0.084 0.4 12 Click to see details
KIRP -0.158 0.19 -0.189 0.15 32 Click to see details
CESC 0.755 0.23 0.500 0.33 3 Click to see details
KICH -0.148 0.24 -0.082 0.35 25 Click to see details
PRAD 0.098 0.25 0.029 0.42 50 Click to see details
ESCA -0.187 0.29 -0.236 0.24 11 Click to see details
BRCA 0.059 0.3 -0.006 0.48 84 Click to see details
LUSC -0.086 0.3 0.042 0.4 38 Click to see details
HNSC -0.058 0.36 0.050 0.38 42 Click to see details
BLCA -0.065 0.4 0.013 0.48 18 Click to see details
THCA -0.03 0.41 -0.163 0.11 59 Click to see details
THCA -0.03 0.41 -0.163 0.11 59 Click to see details
THCA -0.03 0.41 -0.163 0.11 59 Click to see details
91 hsa-miR-125b-2-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT038624 HN1L Jupiter microtubule associated homolog 2 1 1
MIRT038625 KDELC2 KDEL motif containing 2 1 1
MIRT038626 ABHD15 abhydrolase domain containing 15 1 1
MIRT038627 PPP1R12C protein phosphatase 1 regulatory subunit 12C 1 1
MIRT038628 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 1 1
MIRT038629 ASH2L ASH2 like histone lysine methyltransferase complex subunit 1 1
MIRT038630 USP22 ubiquitin specific peptidase 22 1 1
MIRT038631 CSTB cystatin B 1 1
MIRT038632 SYT2 synaptotagmin 2 1 1
MIRT038633 NDUFS7 NADH:ubiquinone oxidoreductase core subunit S7 1 1
MIRT038634 MTA2 metastasis associated 1 family member 2 1 1
MIRT053086 IGF1R insulin like growth factor 1 receptor 3 1
MIRT055788 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT061248 AMOTL1 angiomotin like 1 2 10
MIRT061649 BTG2 BTG anti-proliferation factor 2 2 6
MIRT079046 TNRC6C trinucleotide repeat containing 6C 2 4
MIRT084583 BCL2L11 BCL2 like 11 2 8
MIRT093523 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 2
MIRT097383 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT098030 SOBP sine oculis binding protein homolog 2 2
MIRT186262 TCEB3 elongin A 2 2
MIRT187284 DAZAP2 DAZ associated protein 2 2 10
MIRT361113 LRRC1 leucine rich repeat containing 1 2 2
MIRT443585 FAM84B family with sequence similarity 84 member B 2 2
MIRT452249 TRAM1 translocation associated membrane protein 1 2 2
MIRT476289 GMFB glia maturation factor beta 2 8
MIRT483871 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT484250 ANK1 ankyrin 1 2 2
MIRT499251 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT502270 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 4
MIRT504652 RPL9 ribosomal protein L9 2 6
MIRT505210 UBN2 ubinuclein 2 2 6
MIRT512690 POP1 POP1 homolog, ribonuclease P/MRP subunit 2 2
MIRT517341 ZNF529 zinc finger protein 529 2 4
MIRT518946 LSG1 large 60S subunit nuclear export GTPase 1 2 2
MIRT520866 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT521236 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT528324 GIGYF2 GRB10 interacting GYF protein 2 2 2
MIRT533297 USP46 ubiquitin specific peptidase 46 2 2
MIRT541024 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT544034 ERRFI1 ERBB receptor feedback inhibitor 1 2 2
MIRT547037 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT556102 MOAP1 modulator of apoptosis 1 2 2
MIRT558320 DR1 down-regulator of transcription 1 2 2
MIRT558520 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT566230 PTMA prothymosin, alpha 2 4
MIRT568437 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT570584 OTUD7B OTU deubiquitinase 7B 2 2
MIRT571384 JKAMP JNK1/MAPK8-associated membrane protein 2 2
MIRT572798 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT573864 C9orf78 chromosome 9 open reading frame 78 2 2
MIRT609930 SLC38A1 solute carrier family 38 member 1 2 4
MIRT610437 CSMD2 CUB and Sushi multiple domains 2 2 2
MIRT614407 MURC caveolae associated protein 4 2 2
MIRT618625 GREB1 growth regulation by estrogen in breast cancer 1 2 2
MIRT620605 SAP30 Sin3A associated protein 30 2 2
MIRT635313 FAM179A TOG array regulator of axonemal microtubules 2 2 2
MIRT635918 GLTSCR2 NOP53 ribosome biogenesis factor 2 2
MIRT638507 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT640597 TM9SF4 transmembrane 9 superfamily member 4 2 2
MIRT644066 IQCE IQ motif containing E 2 2
MIRT648287 TRAPPC2L trafficking protein particle complex 2 like 2 2
MIRT653089 SSR3 signal sequence receptor subunit 3 2 2
MIRT654651 PTAFR platelet activating factor receptor 2 2
MIRT658084 FOXR2 forkhead box R2 2 2
MIRT665306 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT665974 SYTL4 synaptotagmin like 4 2 2
MIRT674905 RASSF9 Ras association domain family member 9 2 2
MIRT680085 THAP1 THAP domain containing 1 2 2
MIRT681487 DIP2A disco interacting protein 2 homolog A 2 2
MIRT691243 DFNB59 pejvakin 2 2
MIRT692361 AGTRAP angiotensin II receptor associated protein 2 2
MIRT693034 MB21D1 Mab-21 domain containing 1 2 2
MIRT694478 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT696069 ZNF264 zinc finger protein 264 2 2
MIRT696579 TTC21B tetratricopeptide repeat domain 21B 2 2
MIRT696759 MTFMT mitochondrial methionyl-tRNA formyltransferase 2 2
MIRT697306 ZNF652 zinc finger protein 652 2 2
MIRT698736 STX12 syntaxin 12 2 2
MIRT701055 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT701197 OTUD3 OTU deubiquitinase 3 2 2
MIRT701334 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT703617 FBXO45 F-box protein 45 2 2
MIRT708893 ZNF780A zinc finger protein 780A 2 2
MIRT711621 DGKH diacylglycerol kinase eta 2 2
MIRT713744 TMEM81 transmembrane protein 81 2 2
MIRT715060 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT719711 CD101 CD101 molecule 2 2
MIRT720293 DLGAP3 DLG associated protein 3 2 2
MIRT722605 CCDC152 coiled-coil domain containing 152 2 2
MIRT724565 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-125b-2 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-125b-2 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-125b-2 Methotrexate 126941 NSC740 approved resistant High Colorectal Adenocarcinoma cell line (HT-29)
hsa-mir-125b-2 Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia tissue
hsa-mir-125b-2 Doxorubicin 31703 NSC123127 approved sensitive Low Hepatocellular Carcinoma cell line (Huh-7, HLE, HuH1)
hsa-mir-125b-2 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375)
hsa-mir-125b-2 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-125b-2 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-125b-2 Topotecan 60699 NSC609699 approved resistant cell line (W1)
hsa-mir-125b-2 Vincristine 5978 approved resistant cell line (W1)
hsa-mir-125b-2 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-mir-125b-2 Tamoxifen 2733525 NSC180973 approved resistant tissue (ER-positive breast cancer)
hsa-mir-125b-2 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-125b-2 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-125b-2-3p Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (BGC823)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901)
hsa-miR-125b-2-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-125b-2-3p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-125b-2-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer tissue
hsa-miR-125b-2-3p Fluorouracil 3385 NSC19893 approved resistant High Gastric Cancer tissue
hsa-miR-125b-2-3p Cyclophosphamide + Doxorubicin + Vincristine + Prednisone + Rituximab resistant High Diffuse Large B-Cell Lymphoma cell line (SU-DHL-2)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901, BGC-823)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant High Lung Adenocarcinoma cell line (A549)
hsa-miR-125b-2-3p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HCT8, HCT-116)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-125b-2-3p Antiepileptic Drug sensitive High Pediatric Epilepsy tissue
hsa-miR-125b-2-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-125b-2-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-125b-2-3p 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-miR-125b-2-3p Ethanol+Tamoxifen resistant cell line (LY2)
hsa-miR-125b-2-3p Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-miR-125b-2-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-125b-2-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-125b-2-3p Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR70)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-125b-2-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-125b-2-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-125b-2-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (SGC-7901)
hsa-miR-125b-2-3p Cisplatin 5460033 NSC119875 approved resistant cell line (BGC-823)

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