miRTarBase - #MIRT443823


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pre-miRNA Information
pre-miRNA hsa-mir-6127   
Genomic Coordinates chr1: 22633258 - 22633366
Description Homo sapiens miR-6127 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6127
Sequence 21| UGAGGGAGUGGGUGGGAGG |39
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 17 1 - 22633330 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1235631264 1 dbSNP
rs1456508376 2 dbSNP
rs961421537 3 dbSNP
rs1017317298 4 dbSNP
rs1188516918 10 dbSNP
rs564733534 16 dbSNP
rs777916911 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SH3BP5L   
Synonyms -
Description SH3 binding domain protein 5 like
Transcript NM_030645   
Expression
Putative miRNA Targets on SH3BP5L
3'UTR of SH3BP5L
(miRNA target sites are highlighted)		 
>SH3BP5L|NM_030645|3'UTR
   1 CCGAGGGGCCAGGGTTCCTGGCTTGAATCTGCCACCACGGGCCGGTTGGGGCCCACAGTCTTCTCACGCCCTCTCCTCTG
  81 GGGCCTCGTCTTCCCGAAGGTCCCCTTCTCCAGTGCTTCCCTGGGAGAGGCCAGCTGTGTTCGAGTCCTCTGTGCCTGCC
 161 CTGGCGTTCTCACAGCCTCCCCCTTCCCCTCAGCAGGCGGCTCTCTTTGCCTTACCCATTCAGAAGGCTCGCCCTCGGCG
 241 CTCTGTCTGCCTCTGCCTGCCAGCTCATCACGATCTGCAGGGCATTGACCCTTTGCTTTCCCTTTCTGCTCCCTCTCTTT
 321 CCATCTGTTTGGCTTTTTCCCTCAGGGAACTTGGTCTAGAAGGCACTGGGAAGCTCATCAGAGAAAATGGGTGCTGGGCC
 401 TGAGTACTCCCGTCGGAGGGGATGGACAGTCACCCCTCCCGTTGGTTTCCAGCCCCGCCCCCCTTCCCAAGGCAACTCTG
 481 GAGGGTACCCTAGGTATGCTGCTGAGCCCTGCCCCCCGTCCTGCTCCAGCCTGCCCGTGTGTAACCTGTAAGATGTACTG
 561 TGTGCCTCCGGAAGACACCACCTTTCCCTTCAGCATTCCCTTTCATGACCTGAGGCACTCTGCGATGTGTGCCCCAAAGC
 641 AGAACTTACAGGGCCTGCAGGAAGCTGGTGTCAGGGAGAGAAACCCAACCCCACTGTCAACATAGGGAGCATCACCAACT
 721 CCAGACTGGCTCCTGTGGGTATGGTGTTTCCGCTGGGCTGGGTCCTCAACATTGCCAAGGTGCTAGTGGGTCCCTAAGAG
 801 GGCCCATGTTGGGGGTGAAGTCATGAGGTCCTGAAGGCTTAGGCCCCTGTCATTCCCACCCTCACTCTTGCTGCACAGTT
 881 GTGTTTACTTTTTCTGGGTAGAGGATGCTGAACTGACTCAGCACCCTCCTGCAGGACGGGGTTAGGGAATTTGGTGCTCA
 961 ATTGCTCTCCCTTGCTCTTCCCCAAACTGAAAATACCTACTGCAGGATCCCTCGGGGCACACTGAAGCTTGGCTGCCAAC
1041 CCTCTTACTTCCTTTGTTACAGGGAGGGGTTGGCTTGGGGTGAAAAGTTCTGCCCTCCGCAGGGAGCAGCTCCAGCTGCC
1121 TGGCAGTGCTCCCAGTTTGTAGGGAAGCCACACCAGATCTGGGTGCCTTGGGAGAACCAGTCCTTCCTTTTGACCCACCC
1201 CAGGAAGATGGAGTGCTCTTTTCTAGGCCCATGTTCTGCCAGCAACCGGGATGCGTGGGCAACTGGACTCTGCACGGGGG
1281 TCTACAGGTTGAGGGAGGTTGGTCACAATGAGAACCTCGGGGTTTGAGGTGGCCATGGGCAGACAGCCGAAAGGGAGGGA
1361 GGGTGTGGGTGTGCGTGTGTGCATGTGCTGGTGTGTAAGGGGGAAAGGGTCTTTCCTGGTTTTATTTAAATAAAGTAGTT
1441 TATGTAAC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggAGGG-UGGGUGAGGGAGu 5'
            ||||  :|::||||||| 
Target 5' ttTCCCTTTCTGCTCCCTCt 3'
 297 - 316 157.00 -23.20
2 
miRNA  3' ggAGGGUGGGUGAG-GGAGu 5'
            ||:||| | ||| |||| 
Target 5' ctTCTCACGCCCTCTCCTCt 3'
 60 - 79 133.00 -22.00
3 
miRNA  3' ggAGGGUGGGUGAGGGAGu 5'
            |:: :|:: :|||||| 
Target 5' tgTTTGGCTTTTTCCCTCa 3'
 326 - 344 133.00 -15.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN8638029 58 COSMIC
COSN21074015 236 COSMIC
COSN10046376 259 COSMIC
COSN28753700 287 COSMIC
COSN30542890 306 COSMIC
COSN28791329 679 COSMIC
COSN10046375 720 COSMIC
COSN8638028 782 COSMIC
COSN24889213 937 COSMIC
COSN31487899 937 COSMIC
COSN16379221 940 COSMIC
COSN1441910 958 COSMIC
COSN16129743 967 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781341288 2 dbSNP
rs768856676 3 dbSNP
rs778162316 9 dbSNP
rs1417333961 10 dbSNP
rs747180457 11 dbSNP
rs1252360582 14 dbSNP
rs1159370499 19 dbSNP
rs780403547 20 dbSNP
rs1157843764 22 dbSNP
rs913688359 25 dbSNP
rs1193322225 27 dbSNP
rs1052099240 30 dbSNP
rs1378175045 34 dbSNP
rs1481024757 36 dbSNP
rs1263126298 37 dbSNP
rs1191517122 38 dbSNP
rs1489312515 39 dbSNP
rs748581860 41 dbSNP
rs566758043 43 dbSNP
rs1302225699 44 dbSNP
rs1310708424 48 dbSNP
rs557920918 57 dbSNP
rs77266156 67 dbSNP
rs1279645143 68 dbSNP
rs1343008697 69 dbSNP
rs1205704487 70 dbSNP
rs1253024282 72 dbSNP
rs980687096 76 dbSNP
rs1176476210 84 dbSNP
rs969730779 88 dbSNP
rs1307460347 95 dbSNP
rs1044151519 101 dbSNP
rs917734494 103 dbSNP
rs539192040 108 dbSNP
rs771342138 109 dbSNP
rs1165242417 110 dbSNP
rs1353325735 117 dbSNP
rs991984138 120 dbSNP
rs951457102 121 dbSNP
rs575798564 123 dbSNP
rs911142245 126 dbSNP
rs1438934329 128 dbSNP
rs1365952689 132 dbSNP
rs1458277217 139 dbSNP
rs1297635741 141 dbSNP
rs868151144 142 dbSNP
rs1203532517 143 dbSNP
rs1273526202 144 dbSNP
rs183203046 147 dbSNP
rs995403893 150 dbSNP
rs550227503 153 dbSNP
rs535127768 154 dbSNP
rs995997972 161 dbSNP
rs933841884 162 dbSNP
rs1162316821 166 dbSNP
rs760978817 169 dbSNP
rs1187829476 170 dbSNP
rs1127427 173 dbSNP
rs972489244 175 dbSNP
rs1018703762 176 dbSNP
rs1482363119 179 dbSNP
rs1460220379 180 dbSNP
rs1007117253 181 dbSNP
rs1389748976 182 dbSNP
rs867818001 182 dbSNP
rs1432940723 184 dbSNP
rs1287240148 186 dbSNP
rs546616008 187 dbSNP
rs1210946473 189 dbSNP
rs61837485 191 dbSNP
rs1356153816 195 dbSNP
rs528380153 198 dbSNP
rs1213878092 209 dbSNP
rs564321525 215 dbSNP
rs1336601329 224 dbSNP
rs891972466 227 dbSNP
rs1272141377 228 dbSNP
rs1447259491 230 dbSNP
rs1217277246 231 dbSNP
rs144365369 232 dbSNP
rs1485264100 234 dbSNP
rs114827663 236 dbSNP
rs1420730953 237 dbSNP
rs1407997257 240 dbSNP
rs936431488 241 dbSNP
rs1325506876 242 dbSNP
rs1387256177 245 dbSNP
rs952233631 249 dbSNP
rs748056900 251 dbSNP
rs577355964 253 dbSNP
rs866143793 255 dbSNP
rs1389794842 259 dbSNP
rs1313394120 262 dbSNP
rs1161200062 267 dbSNP
rs1357359203 269 dbSNP
rs924950445 271 dbSNP
rs1455042892 276 dbSNP
rs752382222 277 dbSNP
rs1012392367 285 dbSNP
rs1045154263 287 dbSNP
rs778755179 290 dbSNP
rs1471358415 291 dbSNP
rs1315801842 303 dbSNP
rs1211066191 308 dbSNP
rs1430762924 312 dbSNP
rs1187895177 313 dbSNP
rs1200251314 319 dbSNP
rs896634398 319 dbSNP
rs1035637157 320 dbSNP
rs999609215 321 dbSNP
rs1407603557 323 dbSNP
rs1451501050 323 dbSNP
rs917865438 340 dbSNP
rs1175643120 343 dbSNP
rs1377170945 349 dbSNP
rs745371629 353 dbSNP
rs562984070 356 dbSNP
rs1043670039 359 dbSNP
rs1336071583 367 dbSNP
rs1207208855 368 dbSNP
rs537964220 376 dbSNP
rs946739011 384 dbSNP
rs1234358120 388 dbSNP
rs1465516033 393 dbSNP
rs889673869 398 dbSNP
rs951178012 400 dbSNP
rs1210710806 409 dbSNP
rs1274336898 411 dbSNP
rs1439906692 415 dbSNP
rs1180189081 424 dbSNP
rs1232483627 425 dbSNP
rs918425560 426 dbSNP
rs1195755113 427 dbSNP
rs1393300568 427 dbSNP
rs149626757 429 dbSNP
rs1037305037 435 dbSNP
rs1397213135 440 dbSNP
rs1411421882 441 dbSNP
rs963136504 449 dbSNP
rs1325811441 451 dbSNP
rs1326664269 454 dbSNP
rs1353730858 456 dbSNP
rs939751150 457 dbSNP
rs1018257140 459 dbSNP
rs1368072770 460 dbSNP
rs1232999883 461 dbSNP
rs373660267 462 dbSNP
rs1233918134 464 dbSNP
rs985893351 468 dbSNP
rs1342134403 469 dbSNP
rs983762952 471 dbSNP
rs955606171 476 dbSNP
rs969724545 484 dbSNP
rs915608053 486 dbSNP
rs1215712001 493 dbSNP
rs373569623 494 dbSNP
rs991067984 496 dbSNP
rs1468089414 504 dbSNP
rs1194049879 506 dbSNP
rs764738178 508 dbSNP
rs1321346333 509 dbSNP
rs1476324053 511 dbSNP
rs1422572558 512 dbSNP
rs1035161792 513 dbSNP
rs1437093825 514 dbSNP
rs749097773 516 dbSNP
rs1010501979 517 dbSNP
rs560483830 518 dbSNP
rs891941604 518 dbSNP
rs1327700362 520 dbSNP
rs1319534458 524 dbSNP
rs1455291730 526 dbSNP
rs1407702319 531 dbSNP
rs779753600 532 dbSNP
rs1000603834 534 dbSNP
rs1049753482 536 dbSNP
rs1263897337 537 dbSNP
rs573976560 537 dbSNP
rs1190866073 538 dbSNP
rs1399953219 540 dbSNP
rs1450541863 541 dbSNP
rs1247770046 544 dbSNP
rs1475409509 545 dbSNP
rs1207102024 546 dbSNP
rs1415181142 547 dbSNP
rs998102960 548 dbSNP
rs1158814794 549 dbSNP
rs1386404471 556 dbSNP
rs901092039 564 dbSNP
rs1298122909 565 dbSNP
rs755697563 566 dbSNP
rs1036826802 569 dbSNP
rs903631933 570 dbSNP
rs1291770432 573 dbSNP
rs1334648432 574 dbSNP
rs1044730311 582 dbSNP
rs1262731197 599 dbSNP
rs1348611255 605 dbSNP
rs947749381 611 dbSNP
rs1408434326 621 dbSNP
rs896156242 623 dbSNP
rs1485986020 624 dbSNP
rs1056275581 631 dbSNP
rs138405719 633 dbSNP
rs1423030328 639 dbSNP
rs780636352 648 dbSNP
rs756793318 649 dbSNP
rs918395888 651 dbSNP
rs1479240442 668 dbSNP
rs974335452 682 dbSNP
rs941440127 683 dbSNP
rs1157583849 684 dbSNP
rs911329129 687 dbSNP
rs540610363 690 dbSNP
rs1311596987 695 dbSNP
rs144708919 703 dbSNP
rs1392395402 705 dbSNP
rs1309415132 714 dbSNP
rs1334242482 718 dbSNP
rs1239489878 719 dbSNP
rs1334255125 725 dbSNP
rs1029682671 727 dbSNP
rs1350180847 729 dbSNP
rs989039102 733 dbSNP
rs960951136 737 dbSNP
rs190999829 741 dbSNP
rs978256938 751 dbSNP
rs1196203397 752 dbSNP
rs967268854 755 dbSNP
rs1430916681 759 dbSNP
rs1416893983 760 dbSNP
rs187305963 762 dbSNP
rs1187013572 765 dbSNP
rs1010940918 769 dbSNP
rs1000808697 775 dbSNP
rs765718233 776 dbSNP
rs954159617 780 dbSNP
rs1172302516 787 dbSNP
rs1359160819 790 dbSNP
rs1462787230 793 dbSNP
rs1300318444 794 dbSNP
rs1446686208 794 dbSNP
rs1394811987 796 dbSNP
rs575406915 797 dbSNP
rs1238335637 806 dbSNP
rs1267674751 808 dbSNP
rs1304442301 809 dbSNP
rs1373209092 814 dbSNP
rs1299070131 815 dbSNP
rs556806758 820 dbSNP
rs1023763821 823 dbSNP
rs1275170722 830 dbSNP
rs759936708 836 dbSNP
rs576882998 847 dbSNP
rs998595839 852 dbSNP
rs1197556373 853 dbSNP
rs896125134 853 dbSNP
rs1253304165 855 dbSNP
rs1342729955 856 dbSNP
rs1273670225 857 dbSNP
rs1191248111 871 dbSNP
rs1225822773 873 dbSNP
rs1056075075 882 dbSNP
rs142435669 883 dbSNP
rs1425053202 891 dbSNP
rs1429575989 893 dbSNP
rs897107103 900 dbSNP
rs1038198153 901 dbSNP
rs1446803074 903 dbSNP
rs941153015 905 dbSNP
rs1326808270 910 dbSNP
rs568006746 919 dbSNP
rs911066582 921 dbSNP
rs754082505 924 dbSNP
rs1309273133 925 dbSNP
rs559889692 928 dbSNP
rs546573909 930 dbSNP
rs1037368403 931 dbSNP
rs1370422759 934 dbSNP
rs4307600 936 dbSNP
rs934083237 937 dbSNP
rs570767467 940 dbSNP
rs137922302 941 dbSNP
rs773598097 953 dbSNP
rs1485909199 954 dbSNP
rs1188741882 957 dbSNP
rs938361783 961 dbSNP
rs1477695725 963 dbSNP
rs1254101650 964 dbSNP
rs1182921113 975 dbSNP
rs926239857 977 dbSNP
rs530745009 986 dbSNP
rs563448398 1000 dbSNP
rs979037631 1001 dbSNP
rs1166168052 1003 dbSNP
rs970594394 1004 dbSNP
rs1460039011 1013 dbSNP
rs924332171 1014 dbSNP
rs772247593 1020 dbSNP
rs1023145721 1022 dbSNP
rs945668883 1024 dbSNP
rs915400499 1039 dbSNP
rs1290558177 1043 dbSNP
rs1011925519 1044 dbSNP
rs1251081209 1047 dbSNP
rs1202916221 1048 dbSNP
rs1240883645 1048 dbSNP
rs1399140429 1056 dbSNP
rs960466969 1060 dbSNP
rs1293628335 1062 dbSNP
rs989613892 1065 dbSNP
rs1323330446 1066 dbSNP
rs1226193262 1068 dbSNP
rs1288713903 1073 dbSNP
rs1316968881 1077 dbSNP
rs1217392465 1080 dbSNP
rs1284463120 1081 dbSNP
rs1034634539 1084 dbSNP
rs1189313803 1086 dbSNP
rs1259971478 1087 dbSNP
rs1474441183 1090 dbSNP
rs1028382093 1093 dbSNP
rs540803136 1097 dbSNP
rs761846516 1098 dbSNP
rs1038661178 1099 dbSNP
rs1005480517 1106 dbSNP
rs1227414614 1112 dbSNP
rs889595184 1113 dbSNP
rs1357061107 1120 dbSNP
rs774333488 1124 dbSNP
rs529378630 1127 dbSNP
rs934051780 1128 dbSNP
rs1283229855 1130 dbSNP
rs922717590 1131 dbSNP
rs1228400786 1137 dbSNP
rs1053108469 1139 dbSNP
rs1026781725 1140 dbSNP
rs1352343661 1142 dbSNP
rs934610958 1160 dbSNP
rs113876883 1162 dbSNP
rs1283156808 1167 dbSNP
rs749255600 1168 dbSNP
rs1350866286 1169 dbSNP
rs1323252794 1176 dbSNP
rs376477748 1177 dbSNP
rs1012775347 1178 dbSNP
rs1233647066 1183 dbSNP
rs373960615 1187 dbSNP
rs566766961 1190 dbSNP
rs574465478 1206 dbSNP
rs1379697773 1212 dbSNP
rs35274741 1223 dbSNP
rs894202247 1223 dbSNP
rs1057272861 1245 dbSNP
rs561987363 1247 dbSNP
rs372387624 1248 dbSNP
rs14851 1254 dbSNP
rs14088 1255 dbSNP
rs960435897 1256 dbSNP
rs1234473697 1260 dbSNP
rs1306234462 1263 dbSNP
rs1343554841 1266 dbSNP
rs1219183946 1269 dbSNP
rs1489398302 1272 dbSNP
rs915493898 1273 dbSNP
rs180740037 1274 dbSNP
rs113889770 1275 dbSNP
rs932833730 1276 dbSNP
rs993886011 1277 dbSNP
rs977223637 1278 dbSNP
rs745486027 1284 dbSNP
rs1476978479 1298 dbSNP
rs780867208 1299 dbSNP
rs1139694 1305 dbSNP
rs1419896117 1308 dbSNP
rs1327913487 1312 dbSNP
rs1005865124 1318 dbSNP
rs982784254 1319 dbSNP
rs889739580 1322 dbSNP
rs575468204 1326 dbSNP
rs1368851619 1332 dbSNP
rs1274640451 1335 dbSNP
rs368593957 1339 dbSNP
rs1026917718 1340 dbSNP
rs1436300997 1343 dbSNP
rs1049583524 1347 dbSNP
rs998059980 1348 dbSNP
rs901012565 1349 dbSNP
rs1257628114 1350 dbSNP
rs1053158089 1355 dbSNP
rs1335787612 1361 dbSNP
rs146842598 1364 dbSNP
rs934773579 1367 dbSNP
rs925920884 1368 dbSNP
rs1451123815 1369 dbSNP
rs1041740109 1370 dbSNP
rs1242700035 1375 dbSNP
rs1043085317 1377 dbSNP
rs1422686422 1382 dbSNP
rs894033991 1385 dbSNP
rs948971012 1391 dbSNP
rs1164639158 1397 dbSNP
rs1053952427 1398 dbSNP
rs1456881235 1398 dbSNP
rs1319552394 1399 dbSNP
rs574984359 1404 dbSNP
rs921429752 1415 dbSNP
rs1041225520 1416 dbSNP
rs1235307004 1420 dbSNP
rs1263959856 1425 dbSNP
rs557524027 1426 dbSNP
rs916197705 1441 dbSNP
rs150301796 1442 dbSNP
rs1434850580 1447 dbSNP
rs908641939 1455 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggagggUGGGUGAGGGAGu 5'
                :|:: :|||||| 
Target 5' ---uugGCUUUUUCCCUCa 3'
 		1 - 16
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000366472.5 | 3UTR | UUGGCUUUUUCCCUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
224 hsa-miR-6127 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT083286 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT113617 ATXN7L3B ataxin 7 like 3B 2 2
MIRT134910 CCND2 cyclin D2 2 2
MIRT177172 ARL5B ADP ribosylation factor like GTPase 5B 2 4
MIRT179548 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 2
MIRT180881 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT197052 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 2
MIRT197845 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT267391 TMEM138 transmembrane protein 138 2 2
MIRT312620 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT350379 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT366859 ZXDB zinc finger, X-linked, duplicated B 2 4
MIRT374545 AK2 adenylate kinase 2 2 2
MIRT402072 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT442348 RAB6B RAB6B, member RAS oncogene family 2 2
MIRT442506 OSBP oxysterol binding protein 2 2
MIRT443823 SH3BP5L SH3 binding domain protein 5 like 2 2
MIRT444970 CDH7 cadherin 7 2 2
MIRT445064 C16orf87 chromosome 16 open reading frame 87 2 2
MIRT445323 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT446216 SLC25A44 solute carrier family 25 member 44 2 2
MIRT448107 TCN2 transcobalamin 2 2 2
MIRT448289 ZDHHC3 zinc finger DHHC-type containing 3 2 2
MIRT450258 MED30 mediator complex subunit 30 2 2
MIRT451022 MYH14 myosin heavy chain 14 2 8
MIRT451425 TJP3 tight junction protein 3 2 4
MIRT451930 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452000 FKBP5 FK506 binding protein 5 2 2
MIRT452359 DLX6 distal-less homeobox 6 2 8
MIRT452462 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT453119 HOXC4 homeobox C4 2 2
MIRT453342 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT453485 PITPNM3 PITPNM family member 3 2 2
MIRT453520 C14orf144 chromosome 14 open reading frame 144 2 2
MIRT453553 PRR12 proline rich 12 2 2
MIRT454220 HLA-A major histocompatibility complex, class I, A 2 2
MIRT454302 ZNF134 zinc finger protein 134 2 2
MIRT454394 NRG4 neuregulin 4 2 2
MIRT454486 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454695 KIAA1644 KIAA1644 2 2
MIRT454955 TPM2 tropomyosin 2 2 2
MIRT455021 UBA1 ubiquitin like modifier activating enzyme 1 2 2
MIRT455137 TBC1D25 TBC1 domain family member 25 2 2
MIRT455294 BCL2L1 BCL2 like 1 2 2
MIRT456535 TMEM63A transmembrane protein 63A 2 2
MIRT457109 DCX doublecortin 2 2
MIRT457438 NOL10 nucleolar protein 10 2 2
MIRT457774 ZC3H12B zinc finger CCCH-type containing 12B 2 4
MIRT458605 KCTD2 potassium channel tetramerization domain containing 2 2 2
MIRT459452 TMEM37 transmembrane protein 37 2 2
MIRT459580 NLGN2 neuroligin 2 2 2
MIRT459929 HHIP hedgehog interacting protein 2 8
MIRT460150 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT460659 IGFBP4 insulin like growth factor binding protein 4 2 2
MIRT460693 RNF157 ring finger protein 157 2 2
MIRT460892 UBE2S ubiquitin conjugating enzyme E2 S 2 2
MIRT461550 ACTR3B ARP3 actin related protein 3 homolog B 2 6
MIRT462035 FAAH fatty acid amide hydrolase 2 2
MIRT462460 GCDH glutaryl-CoA dehydrogenase 2 2
MIRT462806 NTN1 netrin 1 2 2
MIRT463002 ZNF740 zinc finger protein 740 2 2
MIRT463920 WNT3 Wnt family member 3 2 2
MIRT464597 UBN2 ubinuclein 2 2 2
MIRT464656 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 4
MIRT464999 TUBB2A tubulin beta 2A class IIa 2 10
MIRT465022 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT465368 TPM3 tropomyosin 3 2 6
MIRT465426 TP53 tumor protein p53 2 2
MIRT465919 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 4
MIRT465999 TMEM189 transmembrane protein 189 2 4
MIRT467355 SP2 Sp2 transcription factor 2 2
MIRT467775 SLC2A4 solute carrier family 2 member 4 2 2
MIRT467883 SLC22A23 solute carrier family 22 member 23 2 2
MIRT468303 SFT2D2 SFT2 domain containing 2 2 2
MIRT469153 RNF121 ring finger protein 121 2 2
MIRT469170 RNF111 ring finger protein 111 2 2
MIRT469568 RARA retinoic acid receptor alpha 2 2
MIRT469677 RAB5B RAB5B, member RAS oncogene family 2 4
MIRT470152 PSME3 proteasome activator subunit 3 2 2
MIRT470176 PSMD11 proteasome 26S subunit, non-ATPase 11 2 4
MIRT470780 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT471536 PAX5 paired box 5 2 2
MIRT472072 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT472186 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472303 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT472701 MYBL1 MYB proto-oncogene like 1 2 2
MIRT473108 MLXIP MLX interacting protein 2 2
MIRT474786 KIAA0895L KIAA0895 like 2 2
MIRT475143 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475216 IL2RB interleukin 2 receptor subunit beta 2 2
MIRT475441 HYOU1 hypoxia up-regulated 1 2 2
MIRT475636 HMGA1 high mobility group AT-hook 1 2 2
MIRT475767 HDLBP high density lipoprotein binding protein 2 2
MIRT476091 GRB2 growth factor receptor bound protein 2 2 2
MIRT476509 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477048 FAM210A family with sequence similarity 210 member A 2 2
MIRT477390 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT477416 EN2 engrailed homeobox 2 2 2
MIRT478602 CTDSP2 CTD small phosphatase 2 2 2
MIRT478893 CREB3L2 cAMP responsive element binding protein 3 like 2 2 4
MIRT479128 CNBP CCHC-type zinc finger nucleic acid binding protein 2 4
MIRT479246 CHTF8 chromosome transmission fidelity factor 8 2 2
MIRT482311 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482774 ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough 2 4
MIRT482822 TRAF6 TNF receptor associated factor 6 2 2
MIRT483320 SLC35C2 solute carrier family 35 member C2 2 4
MIRT483343 CHRDL1 chordin like 1 2 8
MIRT483447 ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor 6 2 6
MIRT483630 NAV2 neuron navigator 2 2 2
MIRT484076 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 4
MIRT484100 EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 2 4
MIRT484219 SUMO1 small ubiquitin-like modifier 1 2 6
MIRT484291 AIP aryl hydrocarbon receptor interacting protein 2 4
MIRT484368 GATA6 GATA binding protein 6 2 12
MIRT484388 ZNF710 zinc finger protein 710 2 4
MIRT484440 RAB7A RAB7A, member RAS oncogene family 2 4
MIRT484586 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT484620 SIX3 SIX homeobox 3 2 6
MIRT484854 ZNF70 zinc finger protein 70 2 4
MIRT485005 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT485837 ARF3 ADP ribosylation factor 3 2 2
MIRT486164 TLE3 transducin like enhancer of split 3 2 2
MIRT486440 NDUFA5 NADH:ubiquinone oxidoreductase subunit A5 2 2
MIRT486578 ZNF619 zinc finger protein 619 2 2
MIRT486636 GFRA1 GDNF family receptor alpha 1 2 2
MIRT486696 GLYR1 glyoxylate reductase 1 homolog 2 2
MIRT486799 PARP11 poly(ADP-ribose) polymerase family member 11 2 2
MIRT486870 DPF1 double PHD fingers 1 2 2
MIRT486904 TSPYL4 TSPY like 4 2 4
MIRT487053 C10orf55 chromosome 10 open reading frame 55 2 2
MIRT487141 NCOR2 nuclear receptor corepressor 2 2 2
MIRT487247 KHSRP KH-type splicing regulatory protein 2 2
MIRT487618 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT487705 CDK14 cyclin dependent kinase 14 2 2
MIRT487842 CLSTN1 calsyntenin 1 2 4
MIRT487915 FBXO44 F-box protein 44 2 2
MIRT487965 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT488131 GPR107 G protein-coupled receptor 107 2 2
MIRT488200 MAT1A methionine adenosyltransferase 1A 2 2
MIRT488247 DNLZ DNL-type zinc finger 2 4
MIRT488518 CD3E CD3e molecule 2 2
MIRT488889 ASTN2 astrotactin 2 2 4
MIRT488981 REXO2 RNA exonuclease 2 2 2
MIRT489063 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT489125 PPFIA3 PTPRF interacting protein alpha 3 2 2
MIRT489539 MRE11A MRE11 homolog, double strand break repair nuclease 2 14
MIRT489628 ALS2CL ALS2 C-terminal like 2 2
MIRT489861 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 2 2
MIRT490305 HOXB13 homeobox B13 2 2
MIRT490664 NKD1 naked cuticle homolog 1 2 6
MIRT490760 SRCIN1 SRC kinase signaling inhibitor 1 2 2
MIRT490839 ADD2 adducin 2 2 2
MIRT491236 KCNA5 potassium voltage-gated channel subfamily A member 5 2 2
MIRT491450 HOXB5 homeobox B5 2 2
MIRT491562 YAE1D1 Yae1 domain containing 1 2 2
MIRT491827 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT492800 PDE4A phosphodiesterase 4A 2 4
MIRT492887 NFIX nuclear factor I X 2 4
MIRT493404 KIAA0513 KIAA0513 2 2
MIRT493682 HAP1 huntingtin associated protein 1 2 2
MIRT493945 EPB41L1 erythrocyte membrane protein band 4.1 like 1 2 2
MIRT494042 DUSP7 dual specificity phosphatase 7 2 4
MIRT494183 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 2
MIRT494713 ARHGAP31 Rho GTPase activating protein 31 2 2
MIRT494903 UCP2 uncoupling protein 2 2 2
MIRT496600 TAGLN transgelin 2 2
MIRT497050 DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B 2 2
MIRT497289 TMEM119 transmembrane protein 119 2 2
MIRT498945 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT499011 CCDC50 coiled-coil domain containing 50 2 2
MIRT499027 MAG myelin associated glycoprotein 2 2
MIRT499525 SBK1 SH3 domain binding kinase 1 2 6
MIRT499568 CCDC88A coiled-coil domain containing 88A 2 2
MIRT499810 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT500176 CHRM3 cholinergic receptor muscarinic 3 2 2
MIRT502241 HOXC6 homeobox C6 2 2
MIRT502323 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT503638 POLR2F RNA polymerase II subunit F 2 4
MIRT510642 TMEM167A transmembrane protein 167A 2 4
MIRT511034 NRF1 nuclear respiratory factor 1 2 2
MIRT512917 UBL4A ubiquitin like 4A 2 2
MIRT520184 WBP2 WW domain binding protein 2 2 2
MIRT527099 VSTM5 V-set and transmembrane domain containing 5 2 2
MIRT529299 AGK acylglycerol kinase 2 2
MIRT532910 ZNF385A zinc finger protein 385A 2 2
MIRT537881 EDA2R ectodysplasin A2 receptor 2 2
MIRT543762 UBXN2B UBX domain protein 2B 2 2
MIRT546668 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT550080 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT560282 HRH2 histamine receptor H2 2 2
MIRT560778 RRP7A ribosomal RNA processing 7 homolog A 2 2
MIRT564299 MED26 mediator complex subunit 26 2 2
MIRT568820 TRIM67 tripartite motif containing 67 2 2
MIRT568907 ATP6V1B1 ATPase H+ transporting V1 subunit B1 2 2
MIRT569193 LRRC3C leucine rich repeat containing 3C 2 2
MIRT569696 FMNL3 formin like 3 2 2
MIRT569735 GPR173 G protein-coupled receptor 173 2 2
MIRT569775 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT570218 SLC27A1 solute carrier family 27 member 1 2 2
MIRT570313 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT570536 RPH3A rabphilin 3A 2 2
MIRT570580 OTUD7B OTU deubiquitinase 7B 2 2
MIRT571304 TPCN2 two pore segment channel 2 2 2
MIRT571584 TOB2 transducer of ERBB2, 2 2 2
MIRT573278 NCAPH non-SMC condensin I complex subunit H 2 2
MIRT573669 HES6 hes family bHLH transcription factor 6 2 2
MIRT574435 SLC7A5 solute carrier family 7 member 5 2 2
MIRT608005 BTBD9 BTB domain containing 9 2 2
MIRT621341 SLC11A1 solute carrier family 11 member 1 2 2
MIRT636387 NAV1 neuron navigator 1 2 4
MIRT645810 OMA1 OMA1 zinc metallopeptidase 2 2
MIRT649925 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT654189 RNMTL1 mitochondrial rRNA methyltransferase 3 2 2
MIRT661224 SCIMP SLP adaptor and CSK interacting membrane protein 2 2
MIRT661448 MORC4 MORC family CW-type zinc finger 4 2 2
MIRT683122 MED28 mediator complex subunit 28 2 2
MIRT688013 GSN gelsolin 2 2
MIRT702788 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT710928 ING5 inhibitor of growth family member 5 2 2
MIRT713049 IFRD1 interferon related developmental regulator 1 2 2
MIRT713581 SLC2A8 solute carrier family 2 member 8 2 2
MIRT714786 ATP6V1A ATPase H+ transporting V1 subunit A 2 2
MIRT719787 PRDM12 PR/SET domain 12 2 2
MIRT722678 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6127 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-6127 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-6127 Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-6127 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-6127 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-6127 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-6127 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)

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