miRTarBase - #MIRT443947


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pre-miRNA Information
pre-miRNA hsa-mir-4481   
Genomic Coordinates chr10: 12653138 - 12653197
Description Homo sapiens miR-4481 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4481
Sequence 1| GGAGUGGGCUGGUGGUU |17
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1299710636 5 dbSNP
rs1433739601 12 dbSNP
rs1266754238 14 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LRIT3   
Synonyms CSNB1F, FIGLER4
Description leucine rich repeat, Ig-like and transmembrane domains 3
Transcript NM_198506   
Expression
Putative miRNA Targets on LRIT3
3'UTR of LRIT3
(miRNA target sites are highlighted)		 
>LRIT3|NM_198506|3'UTR
   1 GGTTCTGCAGCTCAGGTGCATGTGAGCTACAAAACTAGCATCTAAGGGTATAATTGACCCTAGGTTTGGATGACTTTTGG
  81 ACAGACTTTCACATTGTACATGAAAATCACAAATGGAATGCTTTTAAGTATGTTTAAAAAATACCATGAGACCTCTGAAC
 161 TGAAAAGACAAATAATGTTGATTTTTTTTCTTGTGTGGAAAAGGTCTACAGAAATAATTTTTAGAGTGGTGCTTAATAAA
 241 TTATTAATACTTTTTAGGGTAATGTTTTAGTTCTTAAAAATAAGTTCATGTGAAAGTAGCAAGTGAACTCTGTATTTAAA
 321 AATATAGTTTTTTGAGTCATGAGGAAACATTAGCAAAACCAGCTAAGCCTTGATGTTTATTCATGTTCGAAGTGCATTAT
 401 AGCATTTGCTGTGGATGTTTTCTGACATTGCCTAATGGAGAGCGTGGGATCATAAAGGATTTTGTGTTCACTAAGGTTAA
 481 ATCTAACTCACGGGAGAGAGAGGGCTCTGTCTCTTGGTACCATTATGCATTGTGATACTATAGAGTTGTGTTCATATTTC
 561 TTGTAAGAAAAATTTTTGCTTTTCTTTAGAAATATAGGTATTAGCAAAAGTAAGTATACAAAGAGGATTATGACAAATAG
 641 ACCATTTCTTTAAAAATGGTAACTGTTGCATTTAAACACATCGACTGACAGATTATATGGATATTTAAAAATAACTTTAA
 721 ATCAATCTTTTAATATTTTGCTGTTTGCTCTTATGTTCTCCCTTCTTTCTTCCTTCCTTGTCTTCCCTCCCTTTCCTTCC
 801 TTCATTCTTTCTTTCTTCTGCTCTGTCAGAAGATATACAAGTAGCCAAAGCATCACGAGCCAAGCTGTTTGTCTTTTGCC
 881 ATATTGTCTTTTGATTCTCTTGATAAAGAGAAAGCTTTTGAAATTACTTACTGCCCTTTGAAAGTCTGTTTTACAACCCC
 961 AAAGGATATTTTAGGACTTTAAAAGGGAAGCTTCAGTGGATTCATTTGGTTAGATTCTTTTCCTAGGTTAAAAACATCGG
1041 GGAACTTAAATACATAGGAAAGGAGTTCACAAATAAAATTTAGTTTTTTTAGAAAGAGAATATTTTAATAACTGTAGTAT
1121 ACTACAAGAAACATCTCATGGCTTTAAGATTAACGATAGCGATAAGGCCCACTCAAGCATCTCACAGTGGTGATATTACA
1201 TGTCACTTAGCAGGATGCAACCTGGCCTAGGGATTTCCAGAAGACAAGGCCACCTCAGCACAGATGCAACTTTCATAAAT
1281 TTTAGAACAAAGCCTAACCTTACTAGATTAAACTTGCTCTATGAAAGAAACACTTGGTAATTGACCCAGACTGAATACAT
1361 GTATAAGAAATGGGAAAGATCTCCCAAACTCTGAGAACGGTCCTCAAATAGAAGCTCTCCTAGTCAGTTGGTCATCTGAC
1441 CTCTGACTATATCCGGCCTATGACACCAGCCAGCTCCTGCTTTCTGTCTTGTAAGAGCACTGCTGGAATAAACTACTTGA
1521 GCATTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGGUGGU-CGGGUGAGg 5'
            | |: | |||||||| 
Target 5' agCGATAAGGCCCACTCa 3'
 1158 - 1175 147.00 -17.30
2 
miRNA  3' uugGUGGUCGGGUGAGg 5'
             |||||||| :||| 
Target 5' tgaCACCAGCCAGCTCc 3'
 1461 - 1477 122.00 -23.20
3 
miRNA  3' uugguggucGGG--UGAGg 5'
                   |||  |||| 
Target 5' gaaagatctCCCAAACTCt 3'
 1374 - 1392 100.00 -8.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
901027 83 ClinVar
347200 104 ClinVar
347201 233 ClinVar
901028 259 ClinVar
901029 304 ClinVar
347202 390 ClinVar
347203 499 ClinVar
347204 551 ClinVar
901580 627 ClinVar
347205 684 ClinVar
347206 685 ClinVar
347207 855 ClinVar
903515 960 ClinVar
347208 963 ClinVar
903516 1039 ClinVar
903517 1071 ClinVar
347209 1109 ClinVar
347210 1124 ClinVar
899911 1156 ClinVar
347211 1158 ClinVar
899912 1183 ClinVar
347212 1192 ClinVar
347213 1195 ClinVar
901086 1268 ClinVar
347214 1272 ClinVar
347215 1323 ClinVar
347216 1391 ClinVar
901087 1491 ClinVar
347217 1517 ClinVar
COSN14541324 27 COSMIC
COSN31504820 47 COSMIC
COSN31564325 55 COSMIC
COSN26434751 65 COSMIC
COSN30541271 85 COSMIC
COSN20442738 104 COSMIC
COSN17183237 115 COSMIC
COSN30120050 146 COSMIC
COSN31599541 242 COSMIC
COSN20784870 830 COSMIC
COSN31962319 830 COSMIC
COSN15199544 1162 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs754273674 6 dbSNP
rs1443281806 11 dbSNP
rs534220185 18 dbSNP
rs1264305812 25 dbSNP
rs771963573 31 dbSNP
rs1187416813 33 dbSNP
rs953561077 36 dbSNP
rs780174683 37 dbSNP
rs746883781 40 dbSNP
rs1172673759 42 dbSNP
rs1450052739 47 dbSNP
rs1282231068 48 dbSNP
rs765855640 49 dbSNP
rs1401374845 51 dbSNP
rs776640906 52 dbSNP
rs983461462 57 dbSNP
rs1243683956 59 dbSNP
rs535685494 60 dbSNP
rs549439929 61 dbSNP
rs779321492 64 dbSNP
rs909244062 79 dbSNP
rs942045086 83 dbSNP
rs1359563498 85 dbSNP
rs753390159 99 dbSNP
rs549277127 103 dbSNP
rs76050257 104 dbSNP
rs932455522 112 dbSNP
rs373975404 127 dbSNP
rs890871996 133 dbSNP
rs535014343 137 dbSNP
rs1455987746 142 dbSNP
rs1042144600 148 dbSNP
rs1171729751 150 dbSNP
rs1428337728 151 dbSNP
rs916427709 152 dbSNP
rs1323085780 153 dbSNP
rs1490554573 155 dbSNP
rs903484684 161 dbSNP
rs1268282450 169 dbSNP
rs1220426206 180 dbSNP
rs1251855713 182 dbSNP
rs1386355792 182 dbSNP
rs1386255691 188 dbSNP
rs1321730105 195 dbSNP
rs186014219 222 dbSNP
rs1224281590 225 dbSNP
rs1000551533 226 dbSNP
rs1305574921 230 dbSNP
rs116151046 233 dbSNP
rs1223752956 238 dbSNP
rs1344414386 242 dbSNP
rs906471108 247 dbSNP
rs959636930 249 dbSNP
rs1396555827 251 dbSNP
rs538011176 260 dbSNP
rs536898276 264 dbSNP
rs1299297482 269 dbSNP
rs1013692031 273 dbSNP
rs1461882735 276 dbSNP
rs1353124865 279 dbSNP
rs1178953368 280 dbSNP
rs758600887 288 dbSNP
rs1261205226 289 dbSNP
rs556092678 298 dbSNP
rs1197499009 301 dbSNP
rs556856274 304 dbSNP
rs940575419 305 dbSNP
rs573487969 308 dbSNP
rs1036362063 309 dbSNP
rs899165832 320 dbSNP
rs994911493 336 dbSNP
rs1207538766 338 dbSNP
rs1264786219 350 dbSNP
rs1322558327 354 dbSNP
rs950799712 360 dbSNP
rs1240723033 366 dbSNP
rs146742882 369 dbSNP
rs983901173 371 dbSNP
rs909307158 375 dbSNP
rs963679027 389 dbSNP
rs139529995 390 dbSNP
rs778935817 394 dbSNP
rs967625868 397 dbSNP
rs1470529271 401 dbSNP
rs1405780747 411 dbSNP
rs1174574535 425 dbSNP
rs796676536 425 dbSNP
rs1455507159 432 dbSNP
rs932590774 433 dbSNP
rs1249196098 439 dbSNP
rs752372912 444 dbSNP
rs986630329 445 dbSNP
rs1364861030 447 dbSNP
rs1030706016 453 dbSNP
rs1460746854 458 dbSNP
rs1240989765 464 dbSNP
rs912362116 466 dbSNP
rs1350862043 467 dbSNP
rs957677403 470 dbSNP
rs1236333986 476 dbSNP
rs945239056 484 dbSNP
rs989657803 485 dbSNP
rs1042504655 492 dbSNP
rs1382538891 493 dbSNP
rs1332532043 497 dbSNP
rs74634233 499 dbSNP
rs936313697 530 dbSNP
rs545098802 531 dbSNP
rs1392894738 536 dbSNP
rs538349764 540 dbSNP
rs564822946 541 dbSNP
rs1405648860 546 dbSNP
rs76150278 551 dbSNP
rs1195131698 568 dbSNP
rs1447357646 573 dbSNP
rs1260654328 574 dbSNP
rs1348907304 586 dbSNP
rs927801319 596 dbSNP
rs1291817033 597 dbSNP
rs1307514455 599 dbSNP
rs1247353500 603 dbSNP
rs1025182716 606 dbSNP
rs1036225712 613 dbSNP
rs1230166927 619 dbSNP
rs1242437273 620 dbSNP
rs1488791881 620 dbSNP
rs1398335621 621 dbSNP
rs1367566000 623 dbSNP
rs1303772196 624 dbSNP
rs1267161665 625 dbSNP
rs550462658 627 dbSNP
rs1005064377 631 dbSNP
rs1203857266 633 dbSNP
rs1272008489 634 dbSNP
rs1016737571 643 dbSNP
rs1383376915 649 dbSNP
rs1169542770 662 dbSNP
rs1475646350 663 dbSNP
rs375326266 665 dbSNP
rs1372238485 668 dbSNP
rs963524146 683 dbSNP
rs564004924 684 dbSNP
rs4698798 685 dbSNP
rs1221168623 690 dbSNP
rs954696528 696 dbSNP
rs1288400442 697 dbSNP
rs1198056270 698 dbSNP
rs1340532269 699 dbSNP
rs1269941195 701 dbSNP
rs1251604633 708 dbSNP
rs1423607219 722 dbSNP
rs542240600 748 dbSNP
rs986684138 751 dbSNP
rs1348178339 753 dbSNP
rs1330835803 755 dbSNP
rs912497873 756 dbSNP
rs1395510836 762 dbSNP
rs1387667091 767 dbSNP
rs945182598 769 dbSNP
rs977973361 771 dbSNP
rs1019163749 773 dbSNP
rs903343695 777 dbSNP
rs1429640356 778 dbSNP
rs999135632 788 dbSNP
rs1168092702 804 dbSNP
rs1479200574 805 dbSNP
rs925008141 812 dbSNP
rs1234067751 821 dbSNP
rs116786378 824 dbSNP
rs1438834659 826 dbSNP
rs1054714290 829 dbSNP
rs1431934717 835 dbSNP
rs894774899 837 dbSNP
rs1197212805 841 dbSNP
rs989173141 851 dbSNP
rs6830168 855 dbSNP
rs1314729853 857 dbSNP
rs1383496514 858 dbSNP
rs781388896 863 dbSNP
rs982264122 865 dbSNP
rs1335160179 866 dbSNP
rs1227001198 869 dbSNP
rs886710351 870 dbSNP
rs374407364 876 dbSNP
rs1016466951 881 dbSNP
rs1343681566 882 dbSNP
rs1406517211 889 dbSNP
rs1204705594 895 dbSNP
rs78668024 898 dbSNP
rs971849927 907 dbSNP
rs920526153 909 dbSNP
rs1469175789 912 dbSNP
rs372231507 925 dbSNP
rs1199137537 935 dbSNP
rs996237022 944 dbSNP
rs1462953242 945 dbSNP
rs1029092008 948 dbSNP
rs930523977 957 dbSNP
rs954666885 960 dbSNP
rs10011256 963 dbSNP
rs1019526864 965 dbSNP
rs966678270 978 dbSNP
rs978319370 979 dbSNP
rs1307057909 981 dbSNP
rs111245161 982 dbSNP
rs191289678 983 dbSNP
rs868117184 986 dbSNP
rs1388331721 1006 dbSNP
rs1335766479 1015 dbSNP
rs1445381191 1016 dbSNP
rs1346660333 1024 dbSNP
rs1318529895 1026 dbSNP
rs1399661511 1027 dbSNP
rs958111298 1038 dbSNP
rs182511132 1039 dbSNP
rs770149854 1040 dbSNP
rs1446900089 1042 dbSNP
rs1386261412 1043 dbSNP
rs1181700583 1046 dbSNP
rs903374638 1050 dbSNP
rs776069110 1055 dbSNP
rs1216743856 1067 dbSNP
rs1358838081 1074 dbSNP
rs999042167 1084 dbSNP
rs79289779 1091 dbSNP
rs1283925970 1092 dbSNP
rs1304425512 1094 dbSNP
rs916343016 1097 dbSNP
rs749828551 1109 dbSNP
rs1359997697 1112 dbSNP
rs1054597998 1118 dbSNP
rs1434188013 1121 dbSNP
rs12642452 1124 dbSNP
rs908113215 1125 dbSNP
rs1023337274 1127 dbSNP
rs1358078150 1128 dbSNP
rs1304370022 1135 dbSNP
rs1424726164 1137 dbSNP
rs940992754 1155 dbSNP
rs1214674799 1156 dbSNP
rs572997541 1158 dbSNP
rs899298980 1161 dbSNP
rs961741853 1162 dbSNP
rs144186836 1168 dbSNP
rs1050478266 1174 dbSNP
rs367574898 1177 dbSNP
rs187509820 1186 dbSNP
rs774747805 1188 dbSNP
rs574005997 1192 dbSNP
rs1187229270 1193 dbSNP
rs56285361 1195 dbSNP
rs1344297088 1197 dbSNP
rs1032680845 1201 dbSNP
rs1456805920 1206 dbSNP
rs1356647706 1207 dbSNP
rs1171499298 1210 dbSNP
rs1465425225 1217 dbSNP
rs1421847506 1222 dbSNP
rs957865915 1225 dbSNP
rs990631960 1228 dbSNP
rs944684904 1232 dbSNP
rs1189402846 1233 dbSNP
rs916311895 1237 dbSNP
rs1040374448 1239 dbSNP
rs1251802742 1244 dbSNP
rs1197850993 1246 dbSNP
rs1315800480 1250 dbSNP
rs970485178 1255 dbSNP
rs563968164 1259 dbSNP
rs1223697052 1266 dbSNP
rs190337829 1268 dbSNP
rs1298476453 1271 dbSNP
rs35043368 1272 dbSNP
rs1054628073 1296 dbSNP
rs1299243230 1299 dbSNP
rs1446569092 1307 dbSNP
rs146584985 1323 dbSNP
rs1178886830 1326 dbSNP
rs1369380436 1333 dbSNP
rs893289338 1333 dbSNP
rs1346931962 1334 dbSNP
rs1013198645 1351 dbSNP
rs1045027414 1352 dbSNP
rs907430593 1360 dbSNP
rs1456287198 1361 dbSNP
rs1003177307 1363 dbSNP
rs1037929976 1365 dbSNP
rs1034615062 1368 dbSNP
rs961774029 1378 dbSNP
rs1253858891 1385 dbSNP
rs920864925 1390 dbSNP
rs200634605 1391 dbSNP
rs1283544283 1393 dbSNP
rs1310651173 1399 dbSNP
rs528703764 1400 dbSNP
rs1050614925 1404 dbSNP
rs1339053439 1410 dbSNP
rs1453811056 1424 dbSNP
rs1401816871 1425 dbSNP
rs1301313564 1428 dbSNP
rs890534938 1429 dbSNP
rs1364397125 1431 dbSNP
rs1009021970 1438 dbSNP
rs1437701943 1447 dbSNP
rs1386881702 1454 dbSNP
rs1228199855 1455 dbSNP
rs1441597882 1458 dbSNP
rs1042196063 1466 dbSNP
rs1266748233 1478 dbSNP
rs1319307424 1479 dbSNP
rs1485913566 1480 dbSNP
rs910477102 1482 dbSNP
rs183244433 1491 dbSNP
rs796449314 1492 dbSNP
rs546934384 1508 dbSNP
rs1000616683 1512 dbSNP
rs886058987 1517 dbSNP
rs958218059 1524 dbSNP
rs571436639 1525 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuGGUGGUCGGGUGagg 5'
            | | || |:|||   
Target 5' -uCAAGCAUCUCACag- 3'
 		1 - 15
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000594814.1 | 3UTR | UCAAGCAUCUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000594814.1 | 3UTR | UCAAGCAUCUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
84 hsa-miR-4481 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT100715 TJAP1 tight junction associated protein 1 2 2
MIRT183589 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT338033 DAZAP2 DAZ associated protein 2 2 4
MIRT395796 SPCS3 signal peptidase complex subunit 3 2 2
MIRT443947 LRIT3 leucine rich repeat, Ig-like and transmembrane domains 3 2 2
MIRT450580 HIST1H2BG histone cluster 1 H2B family member g 2 6
MIRT451617 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT452331 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT453279 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT455212 GNL1 G protein nucleolar 1 (putative) 2 2
MIRT455470 LYPLA2 lysophospholipase II 2 2
MIRT456503 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2 2
MIRT456687 LDB1 LIM domain binding 1 2 2
MIRT456915 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457603 IDS iduronate 2-sulfatase 2 2
MIRT457848 RNASEH2B ribonuclease H2 subunit B 2 4
MIRT458455 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT460179 UNK unkempt family zinc finger 2 6
MIRT461465 SLC19A3 solute carrier family 19 member 3 2 2
MIRT464739 UBE2Q1 ubiquitin conjugating enzyme E2 Q1 2 2
MIRT465279 TRIM28 tripartite motif containing 28 2 2
MIRT468450 SETD1B SET domain containing 1B 2 2
MIRT468620 SUMO1 small ubiquitin-like modifier 1 2 6
MIRT469152 RNF121 ring finger protein 121 2 2
MIRT470073 PTGES2 prostaglandin E synthase 2 2 2
MIRT470172 PSMD11 proteasome 26S subunit, non-ATPase 11 2 4
MIRT473156 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT474308 LAMC1 laminin subunit gamma 1 2 2
MIRT474782 KIAA0895L KIAA0895 like 2 2
MIRT476484 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477613 EFNA3 ephrin A3 2 2
MIRT479525 CDCA4 cell division cycle associated 4 2 2
MIRT479973 CARD10 caspase recruitment domain family member 10 2 2
MIRT480410 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480426 C17orf85 nuclear cap binding subunit 3 2 2
MIRT483573 SYT2 synaptotagmin 2 2 2
MIRT483664 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT484532 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484616 SIX3 SIX homeobox 3 2 6
MIRT485897 ZFP36 ZFP36 ring finger protein 2 2
MIRT486505 MYH11 myosin heavy chain 11 2 2
MIRT487505 GRK5 G protein-coupled receptor kinase 5 2 2
MIRT488852 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489464 MSC musculin 2 2
MIRT491170 LRP3 LDL receptor related protein 3 2 2
MIRT496627 TMEM67 transmembrane protein 67 2 2
MIRT497616 ANG angiogenin 2 2
MIRT497766 KIAA0895 KIAA0895 2 2
MIRT499680 MRE11A MRE11 homolog, double strand break repair nuclease 2 6
MIRT499774 SLC29A2 solute carrier family 29 member 2 2 2
MIRT501745 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT504995 ZNF652 zinc finger protein 652 2 2
MIRT511664 HIST1H3C histone cluster 1 H3 family member c 2 2
MIRT511690 HIST1H2BO histone cluster 1 H2B family member o 2 4
MIRT511703 HIST1H2BL histone cluster 1 H2B family member l 2 4
MIRT511734 HIST1H2BE histone cluster 1 H2B family member e 2 8
MIRT512858 TBC1D13 TBC1 domain family member 13 2 2
MIRT513444 EMP1 epithelial membrane protein 1 2 6
MIRT515681 TFPI tissue factor pathway inhibitor 2 2
MIRT523529 GLUL glutamate-ammonia ligase 2 2
MIRT525546 PHB2 prohibitin 2 2 4
MIRT526209 SNX24 sorting nexin 24 2 2
MIRT531554 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT533764 TMEM135 transmembrane protein 135 2 2
MIRT545582 SNRPA1 small nuclear ribonucleoprotein polypeptide A' 2 2
MIRT552434 ZNF460 zinc finger protein 460 2 2
MIRT561159 BCL2L12 BCL2 like 12 2 2
MIRT562345 EXOSC2 exosome component 2 2 2
MIRT570659 KDM6B lysine demethylase 6B 2 2
MIRT571076 TCHHL1 trichohyalin like 1 2 2
MIRT571330 TPCN2 two pore segment channel 2 2 2
MIRT571603 TOB2 transducer of ERBB2, 2 2 2
MIRT573013 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT609041 EP300 E1A binding protein p300 2 2
MIRT613398 DNAH17 dynein axonemal heavy chain 17 2 2
MIRT635589 TTC9C tetratricopeptide repeat domain 9C 2 2
MIRT661118 FPR1 formyl peptide receptor 1 2 2
MIRT690103 PNMA2 paraneoplastic Ma antigen 2 2 2
MIRT694972 PLAC8 placenta specific 8 2 2
MIRT695515 ALPI alkaline phosphatase, intestinal 2 2
MIRT695578 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT699570 SIT1 signaling threshold regulating transmembrane adaptor 1 2 2
MIRT701991 MIER3 MIER family member 3 2 2
MIRT725464 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4481 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-mir-4481 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-4481 Tamoxifen 2733525 NSC180973 approved resistant cell line (MCF7)
hsa-mir-4481 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4481 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4481 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4481 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4481 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4481 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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