miRTarBase - #MIRT444215


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pre-miRNA Information
pre-miRNA hsa-mir-3915   
Genomic Coordinates chrX: 32583656 - 32583752
Description Homo sapiens miR-3915 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3915
Sequence 21| UUGAGGAAAAGAUGGUCUUAUU |42
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs997323565 10 dbSNP
rs1192161547 15 dbSNP
rs1255075246 19 dbSNP
rs1452812574 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol METTL12   
Synonyms U99HG
Description methyltransferase like 12
Transcript NM_001043229   
Expression
Putative miRNA Targets on METTL12
3'UTR of METTL12
(miRNA target sites are highlighted)		 
>METTL12|NM_001043229|3'UTR
   1 AGACATTTTAGTAGTCCTGACCCTAGTATTTCTGTGGGCAAGGAGAGGGCTGAAGAACTGTCTTTGCAAGCTATCTGGCT
  81 GCAAAGTGAGAATTTGAGTCCTGGCTTCCACATTTACTAGCTGGGTGCCATATTGCTGAATGTTTCTGTTCCCCAGTTTA
 161 CTCATCTGCAGAGTGAGAATAACTTGGAGTTACGGAGATTACATACAATGATGTGCGCAATATTTAGCACAAAATGAATG
 241 CTGAAAAGAGAAGGTACAATTGGGTCATTCCCCAGTTTCAACTAACTGGAGCTCCTAAAAGCAGCAGACAGGAACTGAAT
 321 CAAAACCCCTGCGCTGACTGACTTGTATAATCTAGTGGCCTAACCTGTAAGCCTCATTTTTGTCACCTGTAAAAGGAGAT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuaUUCUGGUAGAAAAGGAGUu 5'
             || ::: ||| |||| || 
Target 5' ctgAATGTT-TCTGTTCCCCAg 3'
 136 - 156 122.00 -6.60
2 
miRNA  3' uuAUUCUGGUAGAAAAGGAGUu 5'
            |:|| || |   |||| || 
Target 5' ttTGAGTCC-TGGCTTCCACAt 3'
 93 - 113 119.00 -6.80
3 
miRNA  3' uuAUUCUGGUAG-AAAAGGAGUu 5'
            |||| || || ||||: ||| 
Target 5' tgTAAG-CC-TCATTTTTGTCAc 3'
 366 - 386 118.00 -8.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31546812 13 COSMIC
COSN30452456 14 COSMIC
COSN30447557 24 COSMIC
COSN31576586 28 COSMIC
COSN31570405 30 COSMIC
COSN30114248 33 COSMIC
COSN30183934 33 COSMIC
COSN23385591 35 COSMIC
COSN20963193 46 COSMIC
COSN30168699 58 COSMIC
COSN31567306 76 COSMIC
COSN20386693 92 COSMIC
COSN20963701 97 COSMIC
COSN31480610 152 COSMIC
COSN17410730 165 COSMIC
COSN31552745 194 COSMIC
COSN26433720 207 COSMIC
COSN30109989 308 COSMIC
COSN31601341 334 COSMIC
COSN31614052 413 COSMIC
COSN30150071 422 COSMIC
COSN30625745 435 COSMIC
COSN30157069 450 COSMIC
COSM6614024 471 COSMIC
COSM4666640 475 COSMIC
COSM5776544 495 COSMIC
COSM7078154 502 COSMIC
COSM929770 537 COSMIC
COSM6069867 544 COSMIC
COSM3980506 567 COSMIC
COSM7712498 575 COSMIC
COSM3451061 587 COSMIC
COSM6614026 594 COSMIC
COSM3416070 596 COSMIC
COSM1298331 614 COSMIC
COSM1684271 615 COSMIC
COSM6908008 619 COSMIC
COSM5694584 631 COSMIC
COSM9522845 634 COSMIC
COSM1355439 648 COSMIC
COSM1676110 653 COSMIC
COSM6614025 671 COSMIC
COSM7163588 671 COSMIC
COSM5839072 674 COSMIC
COSM9833496 683 COSMIC
COSM6581687 695 COSMIC
COSM7665521 706 COSMIC
COSN30158967 712 COSMIC
COSN30170490 712 COSMIC
COSN30516826 712 COSMIC
COSN30477334 714 COSMIC
COSN30179783 725 COSMIC
COSN30531221 738 COSMIC
COSN30183446 744 COSMIC
COSN31614324 784 COSMIC
COSN30526472 798 COSMIC
COSN25312176 1025 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs117916534 3 dbSNP
rs1433203898 9 dbSNP
rs1268445912 12 dbSNP
rs1033054402 13 dbSNP
rs375025349 17 dbSNP
rs1239126373 19 dbSNP
rs1457500892 24 dbSNP
rs758116592 33 dbSNP
rs777783732 36 dbSNP
rs79709755 39 dbSNP
rs1220346052 40 dbSNP
rs771034299 44 dbSNP
rs776646553 46 dbSNP
rs1467030038 47 dbSNP
rs575837186 50 dbSNP
rs1429443084 58 dbSNP
rs1195812748 59 dbSNP
rs1320147467 62 dbSNP
rs1455655517 65 dbSNP
rs538056161 74 dbSNP
rs949946977 86 dbSNP
rs1461926684 91 dbSNP
rs1433667850 97 dbSNP
rs878911903 99 dbSNP
rs955589104 101 dbSNP
rs1177876526 104 dbSNP
rs983424196 113 dbSNP
rs1466093781 138 dbSNP
rs1408376519 141 dbSNP
rs191417550 143 dbSNP
rs1463131260 145 dbSNP
rs1468346806 148 dbSNP
rs578174201 160 dbSNP
rs1210271488 165 dbSNP
rs937011309 172 dbSNP
rs1385983500 174 dbSNP
rs1299900659 178 dbSNP
rs1216623547 185 dbSNP
rs1049283552 186 dbSNP
rs1366392761 186 dbSNP
rs1297079626 190 dbSNP
rs1433202633 194 dbSNP
rs940986674 195 dbSNP
rs184318382 204 dbSNP
rs1465656778 205 dbSNP
rs973719485 206 dbSNP
rs568048221 209 dbSNP
rs940844320 210 dbSNP
rs1036558810 214 dbSNP
rs573649158 216 dbSNP
rs377120219 217 dbSNP
rs117313894 218 dbSNP
rs945243912 221 dbSNP
rs889116453 223 dbSNP
rs530779440 231 dbSNP
rs1254712402 235 dbSNP
rs1207948962 236 dbSNP
rs1000900240 248 dbSNP
rs1343262766 256 dbSNP
rs1274323638 258 dbSNP
rs1226705588 261 dbSNP
rs187110095 262 dbSNP
rs1283913063 267 dbSNP
rs1032828033 271 dbSNP
rs1313711725 280 dbSNP
rs1395470758 296 dbSNP
rs1377103970 299 dbSNP
rs1300973743 303 dbSNP
rs1431516014 317 dbSNP
rs564273174 325 dbSNP
rs1371141892 329 dbSNP
rs956836160 333 dbSNP
rs1369769482 334 dbSNP
rs1187830422 336 dbSNP
rs1399219584 337 dbSNP
rs1439587947 342 dbSNP
rs770090933 346 dbSNP
rs1367777460 347 dbSNP
rs1218117247 348 dbSNP
rs1422679231 350 dbSNP
rs778405450 351 dbSNP
rs775568658 354 dbSNP
rs1220948217 357 dbSNP
rs1259125464 365 dbSNP
rs1253501311 366 dbSNP
rs765650877 369 dbSNP
rs1457541776 381 dbSNP
rs1202771426 383 dbSNP
rs763430769 387 dbSNP
rs764306346 390 dbSNP
rs192961319 391 dbSNP
rs775000759 393 dbSNP
rs1266816595 395 dbSNP
rs747606081 396 dbSNP
rs762370033 396 dbSNP
rs766009048 397 dbSNP
rs1020086542 399 dbSNP
rs753440716 400 dbSNP
rs971213504 401 dbSNP
rs771499177 402 dbSNP
rs556083342 403 dbSNP
rs752236081 408 dbSNP
rs777042192 409 dbSNP
rs1251797706 410 dbSNP
rs758219416 413 dbSNP
rs1203446062 415 dbSNP
rs777395137 417 dbSNP
rs1244380803 420 dbSNP
rs1341771219 422 dbSNP
rs746974325 428 dbSNP
rs1290267657 429 dbSNP
rs1281351799 434 dbSNP
rs1402401267 435 dbSNP
rs1279378316 436 dbSNP
rs899871249 437 dbSNP
rs757230581 446 dbSNP
rs199532450 449 dbSNP
rs760065671 449 dbSNP
rs781071897 452 dbSNP
rs746011566 453 dbSNP
rs1221964874 454 dbSNP
rs769745897 455 dbSNP
rs1489276497 456 dbSNP
rs927253593 459 dbSNP
rs775793113 468 dbSNP
rs749402374 469 dbSNP
rs546870654 473 dbSNP
rs140170783 474 dbSNP
rs775079346 476 dbSNP
rs151251828 480 dbSNP
rs527424664 481 dbSNP
rs149450298 485 dbSNP
rs1361974396 487 dbSNP
rs1487622413 488 dbSNP
rs370358731 490 dbSNP
rs1229013727 493 dbSNP
rs1299392494 496 dbSNP
rs752428625 497 dbSNP
rs926273105 499 dbSNP
rs984504133 500 dbSNP
rs770112982 502 dbSNP
rs762467933 504 dbSNP
rs372883451 505 dbSNP
rs200294500 512 dbSNP
rs751392015 519 dbSNP
rs757038210 526 dbSNP
rs781162085 532 dbSNP
rs76660687 533 dbSNP
rs1445232671 541 dbSNP
rs370296386 542 dbSNP
rs1237842935 545 dbSNP
rs749546913 553 dbSNP
rs768808864 555 dbSNP
rs1381752060 560 dbSNP
rs763842644 561 dbSNP
rs779273504 563 dbSNP
rs1157558498 565 dbSNP
rs1382082999 567 dbSNP
rs748582235 568 dbSNP
rs1399483428 570 dbSNP
rs1373780243 572 dbSNP
rs772508044 578 dbSNP
rs773862019 580 dbSNP
rs761049456 581 dbSNP
rs769372431 583 dbSNP
rs1379358983 589 dbSNP
rs1241081428 590 dbSNP
rs1279047228 592 dbSNP
rs547468928 596 dbSNP
rs762489421 606 dbSNP
rs566996567 609 dbSNP
rs763799494 609 dbSNP
rs1202298437 611 dbSNP
rs1279223042 621 dbSNP
rs201108091 623 dbSNP
rs1001255103 624 dbSNP
rs1347018607 628 dbSNP
rs201392358 630 dbSNP
rs761608130 634 dbSNP
rs185380321 635 dbSNP
rs750404220 637 dbSNP
rs780019376 640 dbSNP
rs753932635 643 dbSNP
rs1429098352 644 dbSNP
rs1361568237 645 dbSNP
rs1478724728 646 dbSNP
rs150429401 647 dbSNP
rs779292143 648 dbSNP
rs1435325425 650 dbSNP
rs1315602439 655 dbSNP
rs1372150993 655 dbSNP
rs748316573 658 dbSNP
rs1009620039 659 dbSNP
rs1335182775 661 dbSNP
rs772599611 664 dbSNP
rs778237158 665 dbSNP
rs267603077 670 dbSNP
rs747381376 673 dbSNP
rs1403452790 674 dbSNP
rs374519514 677 dbSNP
rs1235482188 678 dbSNP
rs1275403982 679 dbSNP
rs777186299 684 dbSNP
rs748802783 686 dbSNP
rs779971436 689 dbSNP
rs763273870 690 dbSNP
rs1318253210 691 dbSNP
rs767464059 692 dbSNP
rs773993967 697 dbSNP
rs1038990864 706 dbSNP
rs147134442 709 dbSNP
rs764356369 710 dbSNP
rs767320802 714 dbSNP
rs200807075 715 dbSNP
rs1279166714 717 dbSNP
rs760486736 718 dbSNP
rs750235856 719 dbSNP
rs140648337 723 dbSNP
rs1394560208 724 dbSNP
rs534222897 726 dbSNP
rs554002350 727 dbSNP
rs1344902652 730 dbSNP
rs765370143 736 dbSNP
rs752993604 737 dbSNP
rs370742944 738 dbSNP
rs542608835 739 dbSNP
rs747396088 740 dbSNP
rs757624529 742 dbSNP
rs1210015345 743 dbSNP
rs1290401672 745 dbSNP
rs1489634149 748 dbSNP
rs372748611 749 dbSNP
rs1419649694 752 dbSNP
rs1433364826 757 dbSNP
rs1372994554 764 dbSNP
rs1169604459 774 dbSNP
rs1004740319 788 dbSNP
rs985132834 789 dbSNP
rs373398449 790 dbSNP
rs1015760682 800 dbSNP
rs962876525 803 dbSNP
rs995704357 814 dbSNP
rs1185575460 819 dbSNP
rs908850781 820 dbSNP
rs1484642364 823 dbSNP
rs1253978240 824 dbSNP
rs1033908548 825 dbSNP
rs962016225 828 dbSNP
rs1229706620 830 dbSNP
rs576476372 835 dbSNP
rs1356658485 841 dbSNP
rs545457050 843 dbSNP
rs1412443654 845 dbSNP
rs1352862864 869 dbSNP
rs1309178002 870 dbSNP
rs1409533006 872 dbSNP
rs991839472 875 dbSNP
rs923047673 876 dbSNP
rs1406150411 880 dbSNP
rs1413417776 884 dbSNP
rs1162873746 886 dbSNP
rs1473618851 887 dbSNP
rs370602751 888 dbSNP
rs917621601 893 dbSNP
rs1403024293 895 dbSNP
rs966476827 898 dbSNP
rs189862022 901 dbSNP
rs144510208 904 dbSNP
rs74695446 907 dbSNP
rs1038940175 912 dbSNP
rs1304366806 925 dbSNP
rs1352561170 926 dbSNP
rs1330619131 940 dbSNP
rs1247096895 943 dbSNP
rs936908924 948 dbSNP
rs1371871923 949 dbSNP
rs1295640201 953 dbSNP
rs1437715060 955 dbSNP
rs868256313 959 dbSNP
rs1054452048 960 dbSNP
rs1357821932 961 dbSNP
rs1349453880 967 dbSNP
rs1324159269 983 dbSNP
rs147417733 985 dbSNP
rs1389513120 995 dbSNP
rs1158568844 996 dbSNP
rs1418406837 1001 dbSNP
rs1405769441 1011 dbSNP
rs1192699911 1022 dbSNP
rs1330679454 1023 dbSNP
rs777143169 1023 dbSNP
rs945409650 1028 dbSNP
rs1251927235 1029 dbSNP
rs1481639565 1031 dbSNP
rs891161359 1036 dbSNP
rs1004282067 1038 dbSNP
rs748260061 1042 dbSNP
rs1214528542 1047 dbSNP
rs1315654554 1049 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000532971.1 | 3UTR | ucaagaauccaacaag
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000532971.1 | 3UTR | ucaagaauccaacaag
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-3915 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059544 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha 2 2
MIRT081703 ZNF507 zinc finger protein 507 2 2
MIRT083311 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT119046 SFT2D3 SFT2 domain containing 3 2 2
MIRT189381 TXLNA taxilin alpha 2 4
MIRT195895 C16ORF72 chromosome 16 open reading frame 72 2 6
MIRT223807 OXR1 oxidation resistance 1 2 2
MIRT292954 ZNF146 zinc finger protein 146 2 4
MIRT293949 RPL13A ribosomal protein L13a 2 6
MIRT300900 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT339332 SESN2 sestrin 2 2 2
MIRT349304 ZNF317 zinc finger protein 317 2 2
MIRT364736 TOR1B torsin family 1 member B 2 2
MIRT366233 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT384605 CLIC4 chloride intracellular channel 4 2 2
MIRT401745 HLA-DRA major histocompatibility complex, class II, DR alpha 2 2
MIRT443169 UBL3 ubiquitin like 3 2 2
MIRT444215 METTL12 methyltransferase like 12 2 2
MIRT444375 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT445340 TCEANC transcription elongation factor A N-terminal and central domain containing 2 2
MIRT445474 KDM6A lysine demethylase 6A 2 2
MIRT445598 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT445630 TMEM50A transmembrane protein 50A 2 2
MIRT446012 VNN1 vanin 1 2 2
MIRT446115 ASTN1 astrotactin 1 2 2
MIRT446248 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT446382 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT446940 ZMAT3 zinc finger matrin-type 3 2 2
MIRT446967 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT447178 PGRMC2 progesterone receptor membrane component 2 2 2
MIRT447209 APBB2 amyloid beta precursor protein binding family B member 2 2 2
MIRT447237 IHH indian hedgehog 2 2
MIRT447807 EMX1 empty spiracles homeobox 1 2 2
MIRT447853 RRP8 ribosomal RNA processing 8 2 4
MIRT448054 MMP15 matrix metallopeptidase 15 2 2
MIRT448094 RASD2 RASD family member 2 2 2
MIRT448704 KLHL11 kelch like family member 11 2 2
MIRT448851 FEM1C fem-1 homolog C 2 2
MIRT449488 ZBTB4 zinc finger and BTB domain containing 4 2 2
MIRT449785 C1orf109 chromosome 1 open reading frame 109 2 2
MIRT450774 PDE3A phosphodiesterase 3A 2 2
MIRT451124 ZNF99 zinc finger protein 99 2 2
MIRT452676 GPR156 G protein-coupled receptor 156 2 2
MIRT452888 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453188 ACSF2 acyl-CoA synthetase family member 2 2 2
MIRT453353 ZNF3 zinc finger protein 3 2 2
MIRT454502 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT454629 FAM83H family with sequence similarity 83 member H 2 2
MIRT455183 AGTRAP angiotensin II receptor associated protein 2 2
MIRT458204 FOXL2 forkhead box L2 2 2
MIRT458723 CES2 carboxylesterase 2 2 2
MIRT458942 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT460304 FLCN folliculin 2 2
MIRT460989 SYT7 synaptotagmin 7 2 2
MIRT461697 ZNF426 zinc finger protein 426 2 2
MIRT461903 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462193 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 2 2
MIRT462290 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463795 XPOT exportin for tRNA 2 2
MIRT464649 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 4
MIRT465911 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 4
MIRT465992 TMEM189 transmembrane protein 189 2 4
MIRT466302 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466575 TBC1D2B TBC1 domain family member 2B 2 2
MIRT470558 POU2F1 POU class 2 homeobox 1 2 2
MIRT471333 PERP PERP, TP53 apoptosis effector 2 2
MIRT471659 PALM2 paralemmin 2 2 2
MIRT472363 TSPAN1 tetraspanin 1 2 2
MIRT473468 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT474702 KIF3A kinesin family member 3A 2 2
MIRT476067 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT476077 GRB2 growth factor receptor bound protein 2 2 2
MIRT476423 GBA2 glucosylceramidase beta 2 2 2
MIRT476463 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT477877 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT478240 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT479460 CDK6 cyclin dependent kinase 6 2 2
MIRT481030 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT491496 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT497585 SLC23A1 solute carrier family 23 member 1 2 2
MIRT498542 TMEM30B transmembrane protein 30B 2 2
MIRT499263 NBPF11 NBPF member 11 2 2
MIRT504698 ZNF117 zinc finger protein 117 2 2
MIRT511288 KLHL15 kelch like family member 15 2 4
MIRT523121 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT529601 H1F0 H1 histone family member 0 2 2
MIRT533481 TRIM71 tripartite motif containing 71 2 2
MIRT535571 NUP37 nucleoporin 37 2 4
MIRT537869 EDA2R ectodysplasin A2 receptor 2 2
MIRT538010 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552681 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT554986 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT556659 KMT2D lysine methyltransferase 2D 2 4
MIRT557437 GTPBP2 GTP binding protein 2 2 2
MIRT560813 CRTAP cartilage associated protein 2 2
MIRT562115 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT563103 IFRD2 interferon related developmental regulator 2 2 2
MIRT574199 LMNB1 lamin B1 2 2
MIRT623920 FMNL3 formin like 3 2 2
MIRT626551 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2 2
MIRT645458 ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 2 2
MIRT649082 CACNA1B calcium voltage-gated channel subunit alpha1 B 2 2
MIRT659477 CLDN1 claudin 1 2 2
MIRT667950 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 2 2
MIRT701981 MIER3 MIER family member 3 2 2
MIRT708694 TFDP2 transcription factor Dp-2 2 2
MIRT709649 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710090 FAM229B family with sequence similarity 229 member B 2 2
MIRT718396 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT724972 TNS1 tensin 1 2 2
MIRT756050 HRH4 histamine receptor H4 2 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3915 Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-3915 Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-3915 Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3915 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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