miRTarBase - #MIRT444255


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pre-miRNA Information
pre-miRNA hsa-mir-548f-1   
Genomic Coordinates chr10: 54607874 - 54607957
Synonyms MIR548F-1, MIRN548F1, hsa-mir-548f-1, MIR548F1
Description Homo sapiens miR-548f-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-2   
Genomic Coordinates chr2: 212426263 - 212426360
Synonyms MIR548F-2, MIRN548F2, hsa-mir-548f-2, MIR548F2
Description Homo sapiens miR-548f-2 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-3   
Genomic Coordinates chr5: 110513829 - 110513915
Synonyms MIR548F-3, MIRN548F3, hsa-mir-548f-3, MIR548F3
Description Homo sapiens miR-548f-3 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-4   
Genomic Coordinates chr7: 147378017 - 147378121
Synonyms MIR548F-4, MIRN548F4, hsa-mir-548f-4, MIR548F4
Description Homo sapiens miR-548f-4 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-5   
Genomic Coordinates chrX: 32641474 - 32641559
Synonyms MIR548F-5, MIRN548F5, hsa-mir-548f-5, MIR548F5
Description Homo sapiens miR-548f-5 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548f-3p
Sequence 59| AAAAACUGUAAUUACUUUU |77
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 10 - 54607905 29233923 MiREDiBase
A-to-I 4 10 - 54607904 29233923 MiREDiBase
A-to-I 5 10 - 54607903 29233923 MiREDiBase
A-to-I 10 10 - 54607898 29233923 MiREDiBase
A-to-I 3 2 - 212426300 29233923 MiREDiBase
A-to-I 4 2 - 212426299 29233923 MiREDiBase
A-to-I 5 2 - 212426298 29233923 MiREDiBase
A-to-I 3 5 - 110513860 29233923 MiREDiBase
A-to-I 4 5 - 110513859 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26988089 5 COSMIC
COSN30456990 6 COSMIC
COSN15625252 6 COSMIC
COSN31522782 7 COSMIC
COSN31545996 8 COSMIC
COSN31570212 9 COSMIC
COSN1084275 12 COSMIC
COSN15625251 15 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs966876049 1 dbSNP
rs1321394893 2 dbSNP
rs923504759 3 dbSNP
rs1168522027 5 dbSNP
rs1187070531 5 dbSNP
rs1485986292 6 dbSNP
rs776299100 6 dbSNP
rs1421488925 6 dbSNP
rs748224431 6 dbSNP
rs1262049804 7 dbSNP
rs1258250226 7 dbSNP
rs568151991 8 dbSNP
rs1233367754 8 dbSNP
rs778777095 9 dbSNP
rs760758823 9 dbSNP
rs1330282349 10 dbSNP
rs749737324 10 dbSNP
rs760103713 10 dbSNP
rs754285569 10 dbSNP
rs756628155 10 dbSNP
rs1380895949 10 dbSNP
rs768673400 12 dbSNP
rs1478761955 13 dbSNP
rs1437534303 15 dbSNP
rs749009182 15 dbSNP
rs773271422 15 dbSNP
rs747569615 15 dbSNP
rs779944053 16 dbSNP
rs771761319 16 dbSNP
rs1159501553 18 dbSNP
rs757404662 19 dbSNP
rs1191871489 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol INTS8   
Synonyms C8orf52, INT8
Description integrator complex subunit 8
Transcript NM_017864   
Expression
Putative miRNA Targets on INTS8
3'UTR of INTS8
(miRNA target sites are highlighted)		 
>INTS8|NM_017864|3'UTR
   1 GCAGTTAAATTTTTTTAACTTTTATTTTTTAAACAATGGGCTAAAAATAAACAGTATTAAAAGGTTAAGTTTATATAATA
  81 CATATGTACACAATTAGTGGTGTTTTCTTTTCAGACAAAATACTGAAACAAATATTAGTTTAAAAACAAACTATACAGAA
 161 GACTTCATACCGTAACAATAAATGTATAGTTTCTTCAAAGGGAGAAGAGATTCACATATCTGATAACAAAATAAACTAGC
 241 AATCTAGTTTTCTAATCTAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuUUCAU--UAAUGUCAAAAa 5'
            || ||  | | :|||||| 
Target 5' taAACTAGCAATCTAGTTTTc 3'
 232 - 252 135.00 -5.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26980529 9 COSMIC
COSN19772227 10 COSMIC
COSN30455782 16 COSMIC
COSN31576707 29 COSMIC
COSN22143445 75 COSMIC
COSN31551470 84 COSMIC
COSN9689114 93 COSMIC
COSN30178041 139 COSMIC
COSN30137147 190 COSMIC
COSN31483065 267 COSMIC
COSN27200385 285 COSMIC
COSN23284911 376 COSMIC
COSN22451871 403 COSMIC
COSN20646185 487 COSMIC
COSN29535242 497 COSMIC
COSN9689115 531 COSMIC
COSN2299780 542 COSMIC
COSN9689116 584 COSMIC
COSN8519653 661 COSMIC
COSN23457321 812 COSMIC
COSN24302521 862 COSMIC
COSN31528706 941 COSMIC
COSN26566124 944 COSMIC
COSN9689117 967 COSMIC
COSN31569053 982 COSMIC
COSN30174409 1072 COSMIC
COSN22115485 1076 COSMIC
COSN22663840 1111 COSMIC
COSN16050004 1132 COSMIC
COSN30162741 1218 COSMIC
COSN31599389 1236 COSMIC
COSN507460 1268 COSMIC
COSN31560643 1304 COSMIC
COSN30712571 1335 COSMIC
COSN507458 1345 COSMIC
COSN25047915 1374 COSMIC
COSN30172885 1393 COSMIC
COSM8314195 1400 COSMIC
COSM8676903 1404 COSMIC
COSM4423619 1439 COSMIC
COSM1102692 1444 COSMIC
COSM9002818 1447 COSMIC
COSM3835176 1480 COSMIC
COSM384984 1498 COSMIC
COSM9328538 1512 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1399511197 2 dbSNP
rs748785965 7 dbSNP
rs780905558 9 dbSNP
rs1267532963 10 dbSNP
rs752360652 10 dbSNP
rs748651472 12 dbSNP
rs755674507 15 dbSNP
rs768103433 16 dbSNP
rs774025691 20 dbSNP
rs1343454062 21 dbSNP
rs1474823668 30 dbSNP
rs1234053774 31 dbSNP
rs761333461 32 dbSNP
rs777475627 37 dbSNP
rs1203268754 39 dbSNP
rs1267452310 40 dbSNP
rs1365629941 48 dbSNP
rs746336031 49 dbSNP
rs1468615824 50 dbSNP
rs767223434 53 dbSNP
rs1302488478 54 dbSNP
rs1225562673 65 dbSNP
rs986805351 69 dbSNP
rs1478927539 73 dbSNP
rs1302592062 74 dbSNP
rs558744963 86 dbSNP
rs535959057 87 dbSNP
rs1296397269 100 dbSNP
rs1184531536 103 dbSNP
rs912126856 104 dbSNP
rs368418645 108 dbSNP
rs1479235531 133 dbSNP
rs1182214177 166 dbSNP
rs770303442 167 dbSNP
rs894935668 168 dbSNP
rs897618205 172 dbSNP
rs1256929090 173 dbSNP
rs930397760 173 dbSNP
rs1206010113 184 dbSNP
rs1321618076 201 dbSNP
rs572575951 213 dbSNP
rs1012391235 214 dbSNP
rs1229018201 217 dbSNP
rs541534802 221 dbSNP
rs1337617189 243 dbSNP
rs1422759620 253 dbSNP
rs906391123 259 dbSNP
rs1323548223 263 dbSNP
rs999294193 270 dbSNP
rs1030880828 271 dbSNP
rs570235774 272 dbSNP
rs1402871628 275 dbSNP
rs144325537 275 dbSNP
rs894144537 280 dbSNP
rs865785764 285 dbSNP
rs893692774 286 dbSNP
rs1404830508 292 dbSNP
rs1159457525 296 dbSNP
rs1439098078 303 dbSNP
rs1012567431 306 dbSNP
rs1180526345 309 dbSNP
rs529553629 313 dbSNP
rs1010940069 324 dbSNP
rs907110641 325 dbSNP
rs561375160 326 dbSNP
rs1185757900 332 dbSNP
rs1460268742 336 dbSNP
rs530026210 339 dbSNP
rs544122306 359 dbSNP
rs964182767 363 dbSNP
rs1259006779 366 dbSNP
rs1238464099 381 dbSNP
rs977227009 383 dbSNP
rs1340942220 392 dbSNP
rs778101200 393 dbSNP
rs951544900 409 dbSNP
rs1381769835 422 dbSNP
rs1227244263 430 dbSNP
rs1290560206 437 dbSNP
rs1453233892 449 dbSNP
rs989579862 450 dbSNP
rs563848436 451 dbSNP
rs1185967694 453 dbSNP
rs1443398764 457 dbSNP
rs1242904191 461 dbSNP
rs1194395323 470 dbSNP
rs982908354 471 dbSNP
rs539099077 497 dbSNP
rs941606389 500 dbSNP
rs986134323 503 dbSNP
rs912162359 507 dbSNP
rs1243670359 515 dbSNP
rs28399589 521 dbSNP
rs1471889621 524 dbSNP
rs1162707858 526 dbSNP
rs1432671751 526 dbSNP
rs200548685 529 dbSNP
rs1407594768 530 dbSNP
rs1161193508 531 dbSNP
rs919433641 531 dbSNP
rs972249162 531 dbSNP
rs930782375 532 dbSNP
rs916219080 539 dbSNP
rs869173157 543 dbSNP
rs947717752 543 dbSNP
rs552361596 553 dbSNP
rs1388367069 556 dbSNP
rs537932642 559 dbSNP
rs894212839 559 dbSNP
rs948425590 560 dbSNP
rs906254863 562 dbSNP
rs1436194532 576 dbSNP
rs1271118839 579 dbSNP
rs1045400008 595 dbSNP
rs1322197594 601 dbSNP
rs935174250 603 dbSNP
rs568382868 604 dbSNP
rs1337205824 605 dbSNP
rs1446719692 605 dbSNP
rs1269446837 620 dbSNP
rs565885074 630 dbSNP
rs34822361 633 dbSNP
rs1347059918 635 dbSNP
rs1300700621 640 dbSNP
rs527429459 647 dbSNP
rs1052214175 650 dbSNP
rs75354615 666 dbSNP
rs1412197627 670 dbSNP
rs771074469 674 dbSNP
rs1167753587 675 dbSNP
rs1480866068 676 dbSNP
rs1431755249 685 dbSNP
rs1222012518 702 dbSNP
rs567284447 705 dbSNP
rs1480156937 711 dbSNP
rs1233317527 716 dbSNP
rs1018302761 725 dbSNP
rs899842535 727 dbSNP
rs1436067506 730 dbSNP
rs1329681030 735 dbSNP
rs998173135 747 dbSNP
rs1280990872 751 dbSNP
rs1222307117 756 dbSNP
rs1373427813 786 dbSNP
rs1029754548 791 dbSNP
rs183676809 792 dbSNP
rs75876478 795 dbSNP
rs1328549552 796 dbSNP
rs1470517881 797 dbSNP
rs774716421 798 dbSNP
rs1008010432 800 dbSNP
rs1018948442 814 dbSNP
rs569977088 824 dbSNP
rs1179074003 827 dbSNP
rs1473778108 831 dbSNP
rs963023475 836 dbSNP
rs1157602613 852 dbSNP
rs1468508034 857 dbSNP
rs1183910164 859 dbSNP
rs368485207 864 dbSNP
rs1261097516 868 dbSNP
rs1458136289 869 dbSNP
rs992165198 870 dbSNP
rs1317198481 877 dbSNP
rs1285716597 878 dbSNP
rs1221603305 889 dbSNP
rs1371744097 894 dbSNP
rs916143716 895 dbSNP
rs1161802038 897 dbSNP
rs1453746334 901 dbSNP
rs1400455331 924 dbSNP
rs1335210291 925 dbSNP
rs1465711964 926 dbSNP
rs1346053512 932 dbSNP
rs771492066 936 dbSNP
rs1399041709 943 dbSNP
rs150813858 950 dbSNP
rs1164130243 958 dbSNP
rs1341760175 965 dbSNP
rs1241018214 972 dbSNP
rs981711167 976 dbSNP
rs927753911 981 dbSNP
rs1182804895 986 dbSNP
rs28399588 986 dbSNP
rs1243508270 987 dbSNP
rs915685837 987 dbSNP
rs572260101 988 dbSNP
rs1315814297 991 dbSNP
rs948501317 1007 dbSNP
rs1291954197 1008 dbSNP
rs1247330828 1011 dbSNP
rs1362279964 1012 dbSNP
rs1439378185 1018 dbSNP
rs1395841512 1020 dbSNP
rs1052242430 1029 dbSNP
rs1290860890 1031 dbSNP
rs893625614 1033 dbSNP
rs144882179 1039 dbSNP
rs1040044800 1043 dbSNP
rs928300055 1045 dbSNP
rs1350999072 1053 dbSNP
rs899709229 1066 dbSNP
rs1426443528 1072 dbSNP
rs998600842 1075 dbSNP
rs934292601 1083 dbSNP
rs554743015 1084 dbSNP
rs887215378 1105 dbSNP
rs1184397811 1117 dbSNP
rs28399587 1129 dbSNP
rs1017002193 1134 dbSNP
rs1279523800 1134 dbSNP
rs1490972592 1136 dbSNP
rs1290235519 1140 dbSNP
rs1011857372 1152 dbSNP
rs1444252993 1158 dbSNP
rs1308441835 1160 dbSNP
rs1298259973 1164 dbSNP
rs1180096574 1174 dbSNP
rs554912176 1181 dbSNP
rs963223317 1185 dbSNP
rs1251795965 1189 dbSNP
rs1473220021 1194 dbSNP
rs1184923150 1196 dbSNP
rs889575601 1200 dbSNP
rs1406863909 1203 dbSNP
rs534023132 1203 dbSNP
rs1007650782 1206 dbSNP
rs1376289531 1209 dbSNP
rs1356052143 1214 dbSNP
rs1013048602 1215 dbSNP
rs35946706 1216 dbSNP
rs1477872973 1219 dbSNP
rs1477274243 1220 dbSNP
rs1019417795 1221 dbSNP
rs1200899766 1221 dbSNP
rs1172861125 1225 dbSNP
rs1267637557 1246 dbSNP
rs1403901715 1247 dbSNP
rs28399586 1248 dbSNP
rs1230052730 1249 dbSNP
rs971666954 1250 dbSNP
rs1370581532 1254 dbSNP
rs966034997 1258 dbSNP
rs1411617377 1262 dbSNP
rs1225361378 1269 dbSNP
rs1284185360 1269 dbSNP
rs993440835 1273 dbSNP
rs1299017937 1274 dbSNP
rs1391876516 1276 dbSNP
rs981783437 1276 dbSNP
rs1330310208 1279 dbSNP
rs1233683375 1284 dbSNP
rs1275730020 1286 dbSNP
rs927613303 1287 dbSNP
rs956483233 1289 dbSNP
rs1406270974 1292 dbSNP
rs1178137412 1294 dbSNP
rs1274057266 1298 dbSNP
rs987861085 1300 dbSNP
rs1050845954 1308 dbSNP
rs1376551390 1316 dbSNP
rs914971545 1331 dbSNP
rs1420160569 1340 dbSNP
rs1253308497 1341 dbSNP
rs946544881 1347 dbSNP
rs1250747129 1348 dbSNP
rs1177094645 1349 dbSNP
rs1432293648 1353 dbSNP
rs1457607159 1355 dbSNP
rs563657635 1357 dbSNP
rs532667648 1358 dbSNP
rs1468186975 1360 dbSNP
rs1159018368 1362 dbSNP
rs1390040899 1364 dbSNP
rs1205795769 1373 dbSNP
rs768965963 1376 dbSNP
rs1324378702 1377 dbSNP
rs776895977 1380 dbSNP
rs1321735044 1391 dbSNP
rs1255460476 1392 dbSNP
rs1387612032 1393 dbSNP
rs1239901859 1394 dbSNP
rs773084730 1394 dbSNP
rs546082315 1396 dbSNP
rs146974676 1398 dbSNP
rs138035191 1403 dbSNP
rs760550653 1404 dbSNP
rs1039504813 1407 dbSNP
rs762832199 1410 dbSNP
rs1229986227 1413 dbSNP
rs766320461 1414 dbSNP
rs376008727 1417 dbSNP
rs759372966 1422 dbSNP
rs1311407052 1427 dbSNP
rs1210018986 1430 dbSNP
rs767275352 1432 dbSNP
rs752373315 1434 dbSNP
rs766405579 1441 dbSNP
rs1413340631 1447 dbSNP
rs928352337 1449 dbSNP
rs28399585 1454 dbSNP
rs1158587292 1459 dbSNP
rs1163196023 1459 dbSNP
rs148191593 1464 dbSNP
rs753875719 1466 dbSNP
rs753412181 1470 dbSNP
rs1394610640 1476 dbSNP
rs1409280323 1484 dbSNP
rs758907019 1489 dbSNP
rs780605182 1490 dbSNP
rs1230190886 1495 dbSNP
rs747525082 1496 dbSNP
rs755345802 1497 dbSNP
rs781445918 1499 dbSNP
rs1004193099 1501 dbSNP
rs758471322 1508 dbSNP
rs1440870539 1512 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000523731.1 | 3UTR | UCAAGUUUUAUAAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000523731.1 | 3UTR | UCAAGUUUUAUAAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA -0.875 0.06 -0.800 0.1 4 Click to see details
BLCA 0.914 0.13 0.500 0.33 3 Click to see details
STAD 0.869 0.16 0.500 0.33 3 Click to see details
HNSC -0.486 0.26 -0.800 0.1 4 Click to see details
UCEC -0.125 0.46 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
LUSC -0.08 0.47 -0.500 0.33 3 Click to see details
153 hsa-miR-548f-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT075032 DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 2 2
MIRT076422 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 2 2
MIRT077732 ZNF652 zinc finger protein 652 2 2
MIRT097425 JMY junction mediating and regulatory protein, p53 cofactor 2 2
MIRT099605 ID4 inhibitor of DNA binding 4, HLH protein 2 4
MIRT105530 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT109834 MID1IP1 MID1 interacting protein 1 2 8
MIRT132952 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT134169 KLHL42 kelch like family member 42 2 4
MIRT138721 MPP5 membrane palmitoylated protein 5 2 2
MIRT187755 ESYT1 extended synaptotagmin 1 2 2
MIRT208054 LRRC58 leucine rich repeat containing 58 2 2
MIRT222029 PURB purine rich element binding protein B 2 2
MIRT243457 LMLN leishmanolysin like peptidase 2 2
MIRT266062 FJX1 four jointed box 1 2 6
MIRT279835 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT285122 TERF2IP TERF2 interacting protein 2 6
MIRT323906 TMEM245 transmembrane protein 245 2 2
MIRT325430 CKS2 CDC28 protein kinase regulatory subunit 2 2 2
MIRT338909 HMGN2 high mobility group nucleosomal binding domain 2 2 6
MIRT350498 MRGBP MRG domain binding protein 2 6
MIRT405877 CALM1 calmodulin 1 2 2
MIRT442081 NDRG1 N-myc downstream regulated 1 2 2
MIRT442371 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT442397 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT444255 INTS8 integrator complex subunit 8 2 2
MIRT444875 ISPD isoprenoid synthase domain containing 2 2
MIRT445407 PTCHD1 patched domain containing 1 2 4
MIRT445493 HMGN4 high mobility group nucleosomal binding domain 4 2 2
MIRT446136 ST6GAL2 ST6 beta-galactoside alpha-2,6-sialyltransferase 2 2 2
MIRT446261 GRAMD1C GRAM domain containing 1C 2 2
MIRT446353 EML6 echinoderm microtubule associated protein like 6 2 2
MIRT446403 SNX1 sorting nexin 1 2 2
MIRT446826 STK17A serine/threonine kinase 17a 2 2
MIRT447222 ABI2 abl interactor 2 2 2
MIRT447705 ERP44 endoplasmic reticulum protein 44 2 2
MIRT448248 ZNF774 zinc finger protein 774 2 2
MIRT448819 FKBP1A FK506 binding protein 1A 2 4
MIRT449060 ZNF558 zinc finger protein 558 2 2
MIRT449668 ZNF451 zinc finger protein 451 2 2
MIRT449974 ZNF555 zinc finger protein 555 2 2
MIRT450476 TRMT5 tRNA methyltransferase 5 2 4
MIRT450483 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT467980 SKIL SKI like proto-oncogene 2 4
MIRT470733 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT475012 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT490478 FEM1C fem-1 homolog C 2 2
MIRT497368 DIRAS2 DIRAS family GTPase 2 2 2
MIRT497561 PRLR prolactin receptor 2 2
MIRT497943 ABCB7 ATP binding cassette subfamily B member 7 2 2
MIRT498014 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT498206 ACVR2B activin A receptor type 2B 2 2
MIRT502637 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT505633 SLC16A1 solute carrier family 16 member 1 2 6
MIRT512261 ARPP19 cAMP regulated phosphoprotein 19 2 6
MIRT518247 SCIN scinderin 2 4
MIRT520483 TRIM13 tripartite motif containing 13 2 4
MIRT521196 SBNO1 strawberry notch homolog 1 2 6
MIRT522764 LARP1 La ribonucleoprotein domain family member 1 2 4
MIRT525021 ABHD13 abhydrolase domain containing 13 2 4
MIRT525100 FRK fyn related Src family tyrosine kinase 2 2
MIRT525268 CD226 CD226 molecule 2 4
MIRT528662 FUNDC2 FUN14 domain containing 2 2 2
MIRT529353 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 2
MIRT529651 ZNF81 zinc finger protein 81 2 2
MIRT529815 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT530316 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT532775 LDHD lactate dehydrogenase D 2 2
MIRT533888 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT535657 NLN neurolysin 2 4
MIRT536351 LEFTY1 left-right determination factor 1 2 2
MIRT538089 DGKE diacylglycerol kinase epsilon 2 2
MIRT538118 DDX6 DEAD-box helicase 6 2 2
MIRT538950 BMP2K BMP2 inducible kinase 2 2
MIRT539086 ARNTL aryl hydrocarbon receptor nuclear translocator like 2 4
MIRT539374 ADSS adenylosuccinate synthase 2 6
MIRT539860 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 4
MIRT539976 SPRY1 sprouty RTK signaling antagonist 1 2 2
MIRT541264 GPC4 glypican 4 2 4
MIRT543374 CYB5B cytochrome b5 type B 2 2
MIRT543472 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT543685 HHLA1 HERV-H LTR-associating 1 2 2
MIRT543877 SLC16A9 solute carrier family 16 member 9 2 2
MIRT544021 KLRC3 killer cell lectin like receptor C3 2 2
MIRT544119 TTLL11 tubulin tyrosine ligase like 11 2 4
MIRT545311 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT545769 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT545991 XKR4 XK related 4 2 2
MIRT546078 VEZF1 vascular endothelial zinc finger 1 2 2
MIRT546717 RNPS1 RNA binding protein with serine rich domain 1 2 4
MIRT548964 CCNT2 cyclin T2 2 2
MIRT552133 MED10 mediator complex subunit 10 2 2
MIRT553941 STARD3NL STARD3 N-terminal like 2 2
MIRT554148 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT555009 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT555495 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT555651 PHF12 PHD finger protein 12 2 2
MIRT557631 GJD3 gap junction protein delta 3 2 2
MIRT557989 FAM160B1 family with sequence similarity 160 member B1 2 2
MIRT558838 CDCA4 cell division cycle associated 4 2 4
MIRT563344 RPLP0 ribosomal protein lateral stalk subunit P0 2 2
MIRT563902 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564263 DEPDC1B DEP domain containing 1B 2 2
MIRT565516 SOX4 SRY-box 4 2 2
MIRT565847 SCML2 Scm polycomb group protein like 2 2 2
MIRT567174 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT573142 ABT1 activator of basal transcription 1 2 2
MIRT573248 ZBTB46 zinc finger and BTB domain containing 46 2 2
MIRT573740 KHSRP KH-type splicing regulatory protein 2 2
MIRT573983 DDX21 DExD-box helicase 21 2 2
MIRT574478 RPS16 ribosomal protein S16 2 2
MIRT608343 ZRANB1 zinc finger RANBP2-type containing 1 2 2
MIRT609782 NHSL1 NHS like 1 2 2
MIRT612536 RSF1 remodeling and spacing factor 1 2 2
MIRT613193 CLOCK clock circadian regulator 2 2
MIRT617539 GRK4 G protein-coupled receptor kinase 4 2 2
MIRT617779 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT620252 PCK1 phosphoenolpyruvate carboxykinase 1 2 2
MIRT621740 TNPO2 transportin 2 2 2
MIRT628105 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT629471 CRLS1 cardiolipin synthase 1 2 6
MIRT638139 TTC26 tetratricopeptide repeat domain 26 2 2
MIRT641039 PITPNB phosphatidylinositol transfer protein beta 2 2
MIRT642453 CLUAP1 clusterin associated protein 1 2 2
MIRT643159 NCK1 NCK adaptor protein 1 2 2
MIRT643260 ZNF566 zinc finger protein 566 2 2
MIRT649827 LIPG lipase G, endothelial type 2 2
MIRT651199 ZNF280B zinc finger protein 280B 2 2
MIRT654633 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 2
MIRT656633 LRRC15 leucine rich repeat containing 15 2 2
MIRT660588 APP amyloid beta precursor protein 2 2
MIRT660865 AFAP1 actin filament associated protein 1 2 2
MIRT664141 ATP6V1G3 ATPase H+ transporting V1 subunit G3 2 2
MIRT666130 SPATS2L spermatogenesis associated serine rich 2 like 2 2
MIRT666391 SHMT1 serine hydroxymethyltransferase 1 2 2
MIRT667143 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT673834 SPPL2A signal peptide peptidase like 2A 2 2
MIRT675539 KIAA1715 lunapark, ER junction formation factor 2 2
MIRT693450 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 2 2
MIRT694852 KRT80 keratin 80 2 2
MIRT696047 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT696951 CERK ceramide kinase 2 2
MIRT697839 UBL3 ubiquitin like 3 2 2
MIRT700270 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT702733 INSIG1 insulin induced gene 1 2 2
MIRT705310 AVL9 AVL9 cell migration associated 2 2
MIRT705325 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT707735 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT711798 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT713736 SUCO SUN domain containing ossification factor 2 2
MIRT715766 SKA2 spindle and kinetochore associated complex subunit 2 2 2
MIRT719186 KCNS2 potassium voltage-gated channel modifier subfamily S member 2 2 2
MIRT719478 PECR peroxisomal trans-2-enoyl-CoA reductase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-548f 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-548f-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-548f-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (1uM)
hsa-miR-548f-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (200nM)
hsa-miR-548f-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (200nM)
hsa-miR-548f-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (500nM)
hsa-miR-548f-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (1uM)
hsa-miR-548f-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (500nM)
hsa-miR-548f-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-548f-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548f-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-548f-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-548f-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-548f-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-548f-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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