miRTarBase - #MIRT444352


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pre-miRNA Information
pre-miRNA hsa-mir-664a   
Genomic Coordinates chr1: 220200538 - 220200619
Description Homo sapiens miR-664 stem-loop
Comment This miRNA sequence overlaps an annotated snoRNA, ACA38b. However, both miR and miR* sequences are identified in reference , and the sequence is homologous with rat mir-664.
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-664a-3p
Sequence 49| UAUUCAUUUAUCCCCAGCCUACA |71
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30457627 12 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1478242335 2 dbSNP
rs1042905485 5 dbSNP
rs908858734 6 dbSNP
rs1229753248 8 dbSNP
rs770101636 12 dbSNP
rs746047168 14 dbSNP
rs1170225715 15 dbSNP
rs1404740911 16 dbSNP
rs1393962832 17 dbSNP
rs1377901643 18 dbSNP
rs1313271494 19 dbSNP
rs1416447585 20 dbSNP
rs1368463251 21 dbSNP
rs1167925254 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KIAA1211   
Synonyms -
Description KIAA1211
Transcript NM_020722   
Expression
Putative miRNA Targets on KIAA1211
3'UTR of KIAA1211
(miRNA target sites are highlighted)		 
>KIAA1211|NM_020722|3'UTR
   1 AGAGTGACTCTCACCCATCCCTACTGCCAGTTATTGGCTCCTCTCTTGCCCTTTTTATTTATTTATTTTTTATATGGGGT
  81 AAAGAAATCAAGCTAGGGAAAAGAAGCATGTTTTATAGGCTCCAAAATAATGTTTAGAAACTGAACTGGTGGTGTTCATT
 161 GTAAAGAGTGGATTTGCACAACCCTAGGTCCTGGTGCCTCGAGCTCCTCCTAGTTCTCAAGAGAAAATTCCGTCCACAGG
 241 ACCACATGAAGCAAAATCTCTAAGCTAAGAACTCGTGAGAGCCTGCCATGCCCATTTCATGGCCTTGCACACACACCCAC
 321 CCACACACCATTCAGAACATGTACTTTTGCCAACCTTTGGTAATGGTTTTTTGATTCTATGCACTAATTTTCTTTGTCCA
 401 AAACATTTACTCTACCATATGTCTGGGAATGTTTATCCTTTCTACAGTAATGGTGAAAGGATCATATCTAGCTAAAAGCA
 481 AGAACACCCATTCTCCTGAATGCAGTGAGTAATTGGGAATCACAAGGAACATTCTGGCACCCAACTGTGCCCATCTTAGT
 561 TTTCATGAGTTTTCCCCACTCTGAAGCTGTAACCCAGAAGGCACATCCATTCACATTTTTACCGCACTGTGGATTCATAG
 641 TGTGGGGCCCTGTTATTCCAATACCCTCCTTAAGGACATGTGAAGCATTTGGCCCAGTTGGCTCCCAGGGAACATTTTAA
 721 TTTAATGTAGTGAAGAAAGACAATTCTAGATCAGAGCTACAAGTTCACTTTCTGTCTCTGAGAATCTCCATCTAGGGCAG
 801 TAGTTCTTATGATGTGTAGGCTCCCTCCTAGGGCCTACTCAATCAGAGCCTGTGGGGACTGGGCCAGGAATATGTATTCT
 881 GGCAAAAACTCTTCAGGTCAGTTCTGATAGATCCCAAAGGTTAAGAACTGTGAGAAACACTGATCCTAATGCAATCTAAT
 961 TTTTCAGACTTCGAAGGGGAGGCTCATTCACTCAAAAAGCAACAGTGAGACAGGAAAAATAATAAAACAACCCCCCAAGC
1041 CAGCCATTTATTACAAGAAGCAACAGGTTATTGACATTACATGTTTGAAAATTCCCTTTGGTCTTTAGGGAAAATAAACA
1121 GGAAGCCAAGATTTGGAGCCTTTGTAATAAGGACTTCCTGCAGAAAGTCTTTTCTTTACTATAATTGAGTAATTCATATT
1201 TAGAGTCACATGTCCAGTAGCATTTCTAATTTTGAGCATTCACCTTGCTACCTTTAAAAAACATCTGAGTTTTAAGTGGC
1281 CTTTTTATCATCATACACATGTGCATACAAAGAAGGGACTTGGCAGTTTAAAAGCCACATATATTCACTTTTATTGCCCT
1361 AAATTTACATGAAACAGACATACTGGCAAACTCACATATTGCTGGTGCTAACCTTATATTTCATAGTGTTGGCATATTCC
1441 CCTTTTCTTAGATTCTTACTCCGAAATATAGGTACACATCCTTTGCTCTGTGCAGAGGGAATTACATCCTTTTTCCTCTC
1521 CTACAAAAACATGCTTTATTAAGTATCCATCATTACTTTCCTTTATGCTCGCTCAATATGCAATGTGCTGTTATTCTACC
1601 ATGTACCTTAAATAAAGGATGATGGCAAAGTTATTTACCATGTAGAAACCATTTTCTTTCTAGAAACAATAGCTCAGCCT
1681 CACTGTAGCAGCTGGCATGTGTGGTCAAGTGGATAGTTGTACTCTTGCAAGTTGGATTTAATATCATATATACTGGACCT
1761 TCAGACTGTTAAAAATCAATGTAACCTTTTTTTATTGCTATGGCAAGCAATTAGTATTTCACTGCACGTCTTCCATACTA
1841 ATGTTCATTTCTAAATCTTATATGTAGGCATTTGTTAGTTCCAATGATTTCCTCACTAATATAACACTTTTTAATGGGAA
1921 TCTTTCCACCTACAGCCCTGGAATGATAATGCTACAGTAATTCTTCTGAATTGACTTTTTCTTTCATCCTGTCAGCTTTG
2001 GACAATATCCCAATTATGGCAGGGAACAGGTGGGGAACTAAGATCAGTTACAAAAAGTTGTAGATGTGTCAACTTTGTAT
2081 TGGCTGGGATATCACTGTGCCCAAACAAAACAGGCGAAATACCTCAGTTAAAATTTTTCCATCAAAGTCTTTAAAAGAAG
2161 AGTATACTGAAGAAAGGGCAGTCACAATACTTACTTCTAACAGCTTCTAAAGGGTACATGTTTAACATTTCATTTCAAAA
2241 TCACCCCAAATTTGCACTAAATACCAATGAAGTGTTATTTTGCTTTAGTAGTCTTCTGAGCAACAAACTATGGGGAATTC
2321 TGTAAAAACATATAAAAAGTTCAAGACTTTTTTTTTAAATGAATGATCACTATGTTAAATGCAAACTTTTTTTTTTTTTT
2401 ATTTAAACAAACATACACTTCTCCTGGCAAGGTTATAGATGATTAACCTCTGTTCATAGACTTATATATAAAACTAGAGG
2481 GTTTTTTGTTTACTTTTTTAATTTTTCAAGTGCAATTGTTTCTTACACAGACATTATTACTATTAAATTATCATTTAGCC
2561 AGTTATCTGCAAATATATAGTATGTATTGTCTCTTCTTGTGACGTTTAGTTTAATTGCTTATTTTAAAGCAGAAACATTA
2641 GTTACAAGTGTCTTACAATATTTTTACCAACAGTAAAGTAGAGACTTAATGAAAATACCTTAGTGTGATTTTAATATAAT
2721 TTGCATATTTTAGTTGTATAAAGTTTTAATGTAAAATGTCCATTATTGAAGGGAAAAGATCTTTCAATAAAAAATACCCA
2801 CGAGATCTTCGGCACTGATGGAATTTGATTTCGATGACCAACTGCAAAACAATCTCATTATATTTACATAACTTTTGTTG
2881 AACAAGAACAACTTTAAACTGTTTTATTACATTTTTTTCC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acauccgaccccuAUUUACUUAu 5'
                       ||||||||| 
Target 5' aagacttttttttTAAATGAATg 3'
 2343 - 2365 150.00 -7.10
2 
miRNA  3' acauCCG---ACCCCUAUUUACUUAu 5'
              |||   || ||  ||:||:|| 
Target 5' agctGGCATGTGTGGTCAAGTGGATa 3'
 1690 - 1715 127.00 -14.81
3 
miRNA  3' acAUCCGACCCCUAU-----UUACUUAu 5'
            |||||    | ||     ||||| | 
Target 5' tgTAGGCATTTGTTAGTTCCAATGATTt 3'
 1863 - 1890 117.00 -7.92
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20048984 11 COSMIC
COSN30502708 22 COSMIC
COSN23749894 27 COSMIC
COSN31572807 50 COSMIC
COSN30586152 66 COSMIC
COSN7495892 94 COSMIC
COSN25171576 169 COSMIC
COSN2034772 228 COSMIC
COSN30104387 348 COSMIC
COSN30191365 352 COSMIC
COSN5271458 360 COSMIC
COSN9045496 397 COSMIC
COSN9045497 398 COSMIC
COSN28764868 399 COSMIC
COSN31588001 453 COSMIC
COSN31544673 463 COSMIC
COSN8870419 472 COSMIC
COSN31516753 483 COSMIC
COSN28615004 491 COSMIC
COSN24300519 508 COSMIC
COSN31493700 517 COSMIC
COSN31595496 526 COSMIC
COSN30147253 535 COSMIC
COSN30526342 543 COSMIC
COSN30144655 551 COSMIC
COSN28676149 556 COSMIC
COSN31508487 565 COSMIC
COSN30472036 639 COSMIC
COSN30516747 650 COSMIC
COSN30508661 694 COSMIC
COSN31512654 702 COSMIC
COSN31566127 712 COSMIC
COSN19689542 743 COSMIC
COSN8491160 779 COSMIC
COSN29141505 810 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs771524745 13 dbSNP
rs772742029 14 dbSNP
rs373670321 16 dbSNP
rs1441009480 20 dbSNP
rs376649482 21 dbSNP
rs1328834965 23 dbSNP
rs759246568 24 dbSNP
rs1270383028 25 dbSNP
rs1340564605 26 dbSNP
rs1198357242 27 dbSNP
rs765122357 28 dbSNP
rs1431885267 29 dbSNP
rs998562255 34 dbSNP
rs1256756179 41 dbSNP
rs1470173333 42 dbSNP
rs1437166860 49 dbSNP
rs956537715 49 dbSNP
rs752556738 51 dbSNP
rs1032760804 53 dbSNP
rs1354728199 54 dbSNP
rs988870370 57 dbSNP
rs1431414231 58 dbSNP
rs1174954650 66 dbSNP
rs1390486829 66 dbSNP
rs1431047145 72 dbSNP
rs113904244 77 dbSNP
rs991145875 78 dbSNP
rs1378827813 94 dbSNP
rs1454037604 95 dbSNP
rs1317777751 97 dbSNP
rs1251704045 99 dbSNP
rs1203562266 101 dbSNP
rs1022614032 103 dbSNP
rs529482179 106 dbSNP
rs981455363 109 dbSNP
rs982359418 117 dbSNP
rs577369634 123 dbSNP
rs868217894 126 dbSNP
rs1310643832 132 dbSNP
rs1303553070 136 dbSNP
rs574730160 141 dbSNP
rs1349857804 145 dbSNP
rs146789707 152 dbSNP
rs972223963 155 dbSNP
rs920712440 172 dbSNP
rs930696554 180 dbSNP
rs1050875006 185 dbSNP
rs202082707 191 dbSNP
rs944627690 192 dbSNP
rs1302019546 193 dbSNP
rs140551201 194 dbSNP
rs1360529517 199 dbSNP
rs373343893 201 dbSNP
rs116782542 202 dbSNP
rs1482795606 209 dbSNP
rs372739680 211 dbSNP
rs1244860342 218 dbSNP
rs998678249 219 dbSNP
rs1473831650 220 dbSNP
rs1251755292 224 dbSNP
rs890874125 229 dbSNP
rs1054203622 232 dbSNP
rs562697402 233 dbSNP
rs1419524908 240 dbSNP
rs1328619256 245 dbSNP
rs1429945971 254 dbSNP
rs1012646711 261 dbSNP
rs1023068673 270 dbSNP
rs971055672 274 dbSNP
rs1039354407 275 dbSNP
rs1311820275 276 dbSNP
rs1394051501 284 dbSNP
rs1380992763 286 dbSNP
rs1336992318 289 dbSNP
rs1004206006 291 dbSNP
rs899526828 300 dbSNP
rs759217029 307 dbSNP
rs962282202 318 dbSNP
rs1455844917 325 dbSNP
rs1359018901 327 dbSNP
rs1032277724 334 dbSNP
rs972255227 347 dbSNP
rs11133436 354 dbSNP
rs11733474 360 dbSNP
rs986198130 361 dbSNP
rs1339332626 371 dbSNP
rs1464594395 374 dbSNP
rs1387120891 378 dbSNP
rs1434957909 387 dbSNP
rs1351380611 388 dbSNP
rs562870713 389 dbSNP
rs910545627 398 dbSNP
rs370092720 404 dbSNP
rs1242429901 405 dbSNP
rs1364094947 414 dbSNP
rs754168134 418 dbSNP
rs757560828 430 dbSNP
rs1433972756 439 dbSNP
rs1300843019 442 dbSNP
rs533096040 445 dbSNP
rs529878270 446 dbSNP
rs551387840 451 dbSNP
rs1322051621 456 dbSNP
rs1322599487 462 dbSNP
rs1382285695 463 dbSNP
rs1389316769 466 dbSNP
rs934562855 467 dbSNP
rs1293491362 468 dbSNP
rs1456796346 469 dbSNP
rs41498446 472 dbSNP
rs1164571531 473 dbSNP
rs892945502 477 dbSNP
rs1013090570 478 dbSNP
rs958719198 482 dbSNP
rs116644059 486 dbSNP
rs1207971081 487 dbSNP
rs1242254815 490 dbSNP
rs6811153 491 dbSNP
rs550002162 498 dbSNP
rs1292282496 501 dbSNP
rs1424006786 503 dbSNP
rs1339707711 504 dbSNP
rs1195662344 507 dbSNP
rs1373808581 509 dbSNP
rs371043757 514 dbSNP
rs758502221 517 dbSNP
rs1330026010 520 dbSNP
rs1396615734 526 dbSNP
rs750534481 528 dbSNP
rs1325135443 531 dbSNP
rs1388002592 532 dbSNP
rs538379546 535 dbSNP
rs142684739 545 dbSNP
rs749589797 546 dbSNP
rs1218417527 547 dbSNP
rs943790468 550 dbSNP
rs1027832305 552 dbSNP
rs952206981 554 dbSNP
rs6834736 556 dbSNP
rs779361664 560 dbSNP
rs748565669 566 dbSNP
rs1269885876 569 dbSNP
rs772576537 574 dbSNP
rs1465313536 575 dbSNP
rs370097464 576 dbSNP
rs746510571 584 dbSNP
rs966511718 585 dbSNP
rs1397728673 587 dbSNP
rs752531410 592 dbSNP
rs770496330 592 dbSNP
rs1419847224 603 dbSNP
rs1406949290 608 dbSNP
rs1204282885 609 dbSNP
rs1284974723 616 dbSNP
rs768857064 624 dbSNP
rs1196064741 625 dbSNP
rs1326801828 628 dbSNP
rs781265523 631 dbSNP
rs1272637923 635 dbSNP
rs1223215534 638 dbSNP
rs1234763827 641 dbSNP
rs1345529103 643 dbSNP
rs892377271 644 dbSNP
rs1409705932 647 dbSNP
rs1349045334 648 dbSNP
rs1284832076 655 dbSNP
rs1410783782 657 dbSNP
rs1401767165 669 dbSNP
rs934593902 671 dbSNP
rs1471005968 676 dbSNP
rs189178984 678 dbSNP
rs1009525909 680 dbSNP
rs1181405279 687 dbSNP
rs554100801 698 dbSNP
rs1182251043 705 dbSNP
rs914411141 713 dbSNP
rs1276078795 714 dbSNP
rs567419828 727 dbSNP
rs1323658086 729 dbSNP
rs780520701 733 dbSNP
rs6811616 743 dbSNP
rs769454902 773 dbSNP
rs958665408 777 dbSNP
rs995459518 779 dbSNP
rs773243065 793 dbSNP
rs1340186906 798 dbSNP
rs1332445571 799 dbSNP
rs1454746935 809 dbSNP
rs1044614153 811 dbSNP
rs114442999 832 dbSNP
rs770587890 838 dbSNP
rs1410050773 839 dbSNP
rs938412643 842 dbSNP
rs1159014532 843 dbSNP
rs199753159 853 dbSNP
rs1159693176 858 dbSNP
rs912703315 874 dbSNP
rs1410774223 884 dbSNP
rs965948220 884 dbSNP
rs1206280470 887 dbSNP
rs1404043088 889 dbSNP
rs975149006 892 dbSNP
rs921021707 914 dbSNP
rs1356131734 917 dbSNP
rs1282738880 923 dbSNP
rs936438164 925 dbSNP
rs1383792469 937 dbSNP
rs1320038545 940 dbSNP
rs371202941 941 dbSNP
rs1433004605 945 dbSNP
rs556381696 949 dbSNP
rs1053443851 950 dbSNP
rs913593519 955 dbSNP
rs4865087 960 dbSNP
rs993752966 965 dbSNP
rs1389157770 970 dbSNP
rs11725686 973 dbSNP
rs906329220 974 dbSNP
rs1002456032 977 dbSNP
rs879047024 986 dbSNP
rs888016786 987 dbSNP
rs1451505481 989 dbSNP
rs1007752472 998 dbSNP
rs1375487333 1003 dbSNP
rs116469820 1007 dbSNP
rs527348461 1011 dbSNP
rs1290410988 1015 dbSNP
rs1359516804 1018 dbSNP
rs966171201 1021 dbSNP
rs1297144436 1023 dbSNP
rs894562310 1024 dbSNP
rs1364194165 1032 dbSNP
rs1224333515 1037 dbSNP
rs1270820024 1040 dbSNP
rs976110915 1043 dbSNP
rs1348048368 1053 dbSNP
rs1031643887 1063 dbSNP
rs540681615 1068 dbSNP
rs181891027 1074 dbSNP
rs1183012585 1077 dbSNP
rs1369647147 1078 dbSNP
rs1234917806 1081 dbSNP
rs533309928 1082 dbSNP
rs1183506109 1094 dbSNP
rs1190117155 1101 dbSNP
rs914529002 1102 dbSNP
rs1267394741 1107 dbSNP
rs1225280567 1117 dbSNP
rs1490623753 1140 dbSNP
rs557724693 1153 dbSNP
rs550088033 1158 dbSNP
rs1167002182 1159 dbSNP
rs1250913528 1164 dbSNP
rs979984342 1167 dbSNP
rs1309448335 1173 dbSNP
rs1370214593 1178 dbSNP
rs928427790 1180 dbSNP
rs1218711089 1182 dbSNP
rs151016936 1188 dbSNP
rs1285123445 1190 dbSNP
rs140812452 1193 dbSNP
rs549133297 1197 dbSNP
rs965538620 1202 dbSNP
rs4865088 1204 dbSNP
rs1305931006 1208 dbSNP
rs896904589 1223 dbSNP
rs1028532471 1228 dbSNP
rs957756409 1239 dbSNP
rs989257728 1245 dbSNP
rs1430736318 1246 dbSNP
rs1314283086 1262 dbSNP
rs1481036106 1282 dbSNP
rs1251592421 1291 dbSNP
rs1382930433 1299 dbSNP
rs534257055 1306 dbSNP
rs1175847995 1313 dbSNP
rs930998314 1317 dbSNP
rs1481776471 1323 dbSNP
rs1233684573 1327 dbSNP
rs1209603605 1335 dbSNP
rs1048076287 1343 dbSNP
rs1265031626 1351 dbSNP
rs765476281 1359 dbSNP
rs1247504944 1370 dbSNP
rs888057282 1371 dbSNP
rs945053913 1374 dbSNP
rs553881624 1382 dbSNP
rs1008199770 1383 dbSNP
rs185857328 1387 dbSNP
rs982018128 1389 dbSNP
rs35854625 1397 dbSNP
rs1407716943 1398 dbSNP
rs1176479748 1400 dbSNP
rs937982336 1403 dbSNP
rs1054866296 1417 dbSNP
rs1157486435 1423 dbSNP
rs901975657 1431 dbSNP
rs1251643882 1437 dbSNP
rs931370405 1440 dbSNP
rs1460133167 1452 dbSNP
rs997562088 1459 dbSNP
rs1048482508 1463 dbSNP
rs556418710 1464 dbSNP
rs1031758546 1470 dbSNP
rs1241045862 1471 dbSNP
rs956117541 1473 dbSNP
rs990138690 1475 dbSNP
rs1243365671 1476 dbSNP
rs901417539 1478 dbSNP
rs1022027310 1481 dbSNP
rs1433735762 1492 dbSNP
rs536880089 1497 dbSNP
rs1382063286 1500 dbSNP
rs980392911 1505 dbSNP
rs576302812 1516 dbSNP
rs1186794572 1517 dbSNP
rs1455762192 1518 dbSNP
rs1028483137 1521 dbSNP
rs1164482922 1525 dbSNP
rs1475874155 1532 dbSNP
rs928490012 1547 dbSNP
rs958205897 1550 dbSNP
rs1387326933 1559 dbSNP
rs959899895 1562 dbSNP
rs1448970781 1566 dbSNP
rs1169856195 1569 dbSNP
rs972553600 1571 dbSNP
rs779702498 1572 dbSNP
rs918365982 1577 dbSNP
rs796312413 1579 dbSNP
rs1048076158 1588 dbSNP
rs542037112 1590 dbSNP
rs910848379 1591 dbSNP
rs1227167260 1595 dbSNP
rs1324198369 1597 dbSNP
rs1297069552 1603 dbSNP
rs1384460368 1621 dbSNP
rs758840880 1631 dbSNP
rs1302988092 1633 dbSNP
rs555890707 1638 dbSNP
rs902092931 1641 dbSNP
rs1367802073 1662 dbSNP
rs1164475657 1663 dbSNP
rs572052527 1669 dbSNP
rs1475193365 1671 dbSNP
rs982182564 1685 dbSNP
rs1406761929 1687 dbSNP
rs927675166 1690 dbSNP
rs766451283 1706 dbSNP
rs1266609102 1712 dbSNP
rs1197111163 1715 dbSNP
rs1177158900 1717 dbSNP
rs751704951 1718 dbSNP
rs1292174481 1719 dbSNP
rs920407020 1742 dbSNP
rs1337008511 1743 dbSNP
rs767397362 1752 dbSNP
rs1053203413 1753 dbSNP
rs1329934334 1758 dbSNP
rs1227797555 1760 dbSNP
rs866096707 1761 dbSNP
rs930482697 1766 dbSNP
rs753318017 1767 dbSNP
rs1304095783 1769 dbSNP
rs1409671615 1774 dbSNP
rs1394583658 1780 dbSNP
rs1048429363 1785 dbSNP
rs1462569321 1786 dbSNP
rs1223304780 1787 dbSNP
rs887181509 1787 dbSNP
rs1174219588 1798 dbSNP
rs754997462 1801 dbSNP
rs1264105082 1802 dbSNP
rs1463056514 1805 dbSNP
rs754464864 1811 dbSNP
rs1180816984 1828 dbSNP
rs1435779935 1828 dbSNP
rs150146816 1838 dbSNP
rs541115383 1839 dbSNP
rs940157328 1842 dbSNP
rs1041423220 1847 dbSNP
rs891906235 1851 dbSNP
rs1011593391 1857 dbSNP
rs781524480 1861 dbSNP
rs1261197482 1862 dbSNP
rs563964614 1863 dbSNP
rs1195646375 1869 dbSNP
rs1050022732 1876 dbSNP
rs970422593 1878 dbSNP
rs893938933 1885 dbSNP
rs532939584 1887 dbSNP
rs1011072949 1889 dbSNP
rs1392135566 1893 dbSNP
rs1001540845 1896 dbSNP
rs1376106008 1902 dbSNP
rs1174327330 1903 dbSNP
rs1021163070 1906 dbSNP
rs1429892474 1911 dbSNP
rs1157871341 1913 dbSNP
rs543764953 1915 dbSNP
rs1460869735 1920 dbSNP
rs1365273805 1930 dbSNP
rs1460576082 1934 dbSNP
rs966845166 1954 dbSNP
rs959929744 1958 dbSNP
rs1461328222 1965 dbSNP
rs1470923090 1966 dbSNP
rs1264306701 1973 dbSNP
rs972583100 1975 dbSNP
rs1003323574 2006 dbSNP
rs748289319 2008 dbSNP
rs1383670705 2014 dbSNP
rs1240084573 2023 dbSNP
rs1382275935 2029 dbSNP
rs1319663360 2030 dbSNP
rs1334864389 2039 dbSNP
rs1454662834 2052 dbSNP
rs760728167 2057 dbSNP
rs918398440 2063 dbSNP
rs952452292 2074 dbSNP
rs1406836455 2076 dbSNP
rs563595823 2077 dbSNP
rs1403886613 2078 dbSNP
rs1398856236 2080 dbSNP
rs1386916536 2082 dbSNP
rs959090655 2090 dbSNP
rs1443688906 2093 dbSNP
rs990659813 2101 dbSNP
rs1184978129 2102 dbSNP
rs910893433 2112 dbSNP
rs1240966673 2113 dbSNP
rs1215771017 2114 dbSNP
rs951996542 2116 dbSNP
rs529168077 2117 dbSNP
rs1227160569 2150 dbSNP
rs1040709737 2163 dbSNP
rs548912832 2175 dbSNP
rs923553603 2178 dbSNP
rs1206992585 2179 dbSNP
rs1313196928 2183 dbSNP
rs939293 2186 dbSNP
rs1269638316 2188 dbSNP
rs1383681028 2188 dbSNP
rs368514809 2193 dbSNP
rs1200333411 2194 dbSNP
rs1318817808 2195 dbSNP
rs940084612 2206 dbSNP
rs1269405328 2210 dbSNP
rs1041147964 2214 dbSNP
rs1165110880 2219 dbSNP
rs1397616700 2220 dbSNP
rs1424880798 2220 dbSNP
rs1418222921 2221 dbSNP
rs1481277945 2232 dbSNP
rs891937359 2234 dbSNP
rs574304900 2245 dbSNP
rs1244350047 2246 dbSNP
rs922571440 2258 dbSNP
rs1321164394 2259 dbSNP
rs1490298223 2260 dbSNP
rs1344417531 2262 dbSNP
rs1363181403 2268 dbSNP
rs1225054182 2273 dbSNP
rs932641759 2279 dbSNP
rs1011662467 2284 dbSNP
rs1272451024 2290 dbSNP
rs1454213679 2299 dbSNP
rs1364083190 2302 dbSNP
rs867676830 2303 dbSNP
rs894061268 2311 dbSNP
rs1343465236 2312 dbSNP
rs1304702250 2318 dbSNP
rs1405254383 2321 dbSNP
rs1353547150 2330 dbSNP
rs1043572323 2335 dbSNP
rs1363104166 2337 dbSNP
rs1411162172 2340 dbSNP
rs1419559154 2342 dbSNP
rs905939380 2349 dbSNP
rs1423674595 2357 dbSNP
rs748070808 2357 dbSNP
rs1303372360 2366 dbSNP
rs10007943 2369 dbSNP
rs1408361119 2374 dbSNP
rs1306673770 2375 dbSNP
rs1042937077 2381 dbSNP
rs1336900561 2383 dbSNP
rs1488975860 2384 dbSNP
rs1222872516 2387 dbSNP
rs1232521388 2387 dbSNP
rs1321333226 2387 dbSNP
rs200966482 2387 dbSNP
rs34984806 2387 dbSNP
rs796920787 2387 dbSNP
rs902695722 2394 dbSNP
rs1241718594 2396 dbSNP
rs1003682453 2399 dbSNP
rs1035674116 2401 dbSNP
rs1443865292 2401 dbSNP
rs1263772770 2402 dbSNP
rs1358802296 2406 dbSNP
rs959962202 2409 dbSNP
rs1294192613 2416 dbSNP
rs1469788105 2417 dbSNP
rs749251441 2419 dbSNP
rs1427826155 2424 dbSNP
rs1011858362 2429 dbSNP
rs1027315186 2432 dbSNP
rs951942802 2433 dbSNP
rs1482170268 2435 dbSNP
rs1238941571 2436 dbSNP
rs770929333 2437 dbSNP
rs541252022 2443 dbSNP
rs1419617273 2447 dbSNP
rs1025489319 2449 dbSNP
rs952486571 2451 dbSNP
rs1183892063 2453 dbSNP
rs1233837877 2454 dbSNP
rs907671732 2457 dbSNP
rs1304557278 2458 dbSNP
rs1225180590 2462 dbSNP
rs1377161819 2465 dbSNP
rs1313842775 2466 dbSNP
rs1449841306 2467 dbSNP
rs1407602488 2468 dbSNP
rs1305133834 2469 dbSNP
rs1466984105 2471 dbSNP
rs983970086 2477 dbSNP
rs1443443244 2478 dbSNP
rs965923667 2480 dbSNP
rs1183153761 2482 dbSNP
rs1381166609 2482 dbSNP
rs977200994 2484 dbSNP
rs1244994837 2494 dbSNP
rs1201017529 2497 dbSNP
rs570539323 2500 dbSNP
rs1258799831 2502 dbSNP
rs963816774 2505 dbSNP
rs976848330 2516 dbSNP
rs922718266 2519 dbSNP
rs932762974 2525 dbSNP
rs922248890 2534 dbSNP
rs1049740577 2537 dbSNP
rs1397584651 2540 dbSNP
rs1393705191 2545 dbSNP
rs560030365 2546 dbSNP
rs1382190593 2550 dbSNP
rs1397191933 2550 dbSNP
rs1246833942 2575 dbSNP
rs58519345 2577 dbSNP
rs190665482 2587 dbSNP
rs756886010 2588 dbSNP
rs947575849 2589 dbSNP
rs13122620 2591 dbSNP
rs1043217274 2592 dbSNP
rs1361530814 2594 dbSNP
rs13122634 2601 dbSNP
rs905963790 2604 dbSNP
rs939545252 2604 dbSNP
rs1204026680 2605 dbSNP
rs570026514 2616 dbSNP
rs937416239 2617 dbSNP
rs1188314870 2620 dbSNP
rs1057165386 2631 dbSNP
rs1250609119 2631 dbSNP
rs1259574421 2635 dbSNP
rs3202838 2637 dbSNP
rs1188158502 2658 dbSNP
rs142058478 2672 dbSNP
rs1290728971 2679 dbSNP
rs545128548 2683 dbSNP
rs1241169681 2686 dbSNP
rs181243500 2699 dbSNP
rs1305190519 2703 dbSNP
rs1294104512 2704 dbSNP
rs1402349910 2705 dbSNP
rs1341578841 2708 dbSNP
rs555733269 2713 dbSNP
rs1183698874 2714 dbSNP
rs1403395596 2718 dbSNP
rs1393160872 2733 dbSNP
rs994089707 2733 dbSNP
rs1386488031 2739 dbSNP
rs1461570134 2740 dbSNP
rs1025607408 2742 dbSNP
rs1027261277 2744 dbSNP
rs572587831 2745 dbSNP
rs1267996466 2759 dbSNP
rs1197001121 2764 dbSNP
rs1005829248 2774 dbSNP
rs1169295250 2782 dbSNP
rs1005183121 2792 dbSNP
rs1479386988 2798 dbSNP
rs1252534487 2800 dbSNP
rs1018088304 2802 dbSNP
rs964153641 2803 dbSNP
rs563233895 2806 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000504228.1 | 3UTR | UCAAGACUUUUUUUUUAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000504228.1 | 3UTR | UCAAGACUUUUUUUUUAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38226 Liver fibrosis -0.412 3.2e-2 -0.089 3.5e-1 21 Click to see details
GSE32688 Pancreatic cancer -0.288 5.5e-2 -0.174 1.7e-1 32 Click to see details
GSE28260 Renal cortex and medulla -0.457 5.8e-2 -0.681 5.2e-3 13 Click to see details
GSE28544 Breast cancer -0.244 1.3e-1 -0.778 3.8e-6 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.224 1.4e-1 -0.366 3.6e-2 25 Click to see details
GSE26953 Aortic valvular endothelial cells -0.091 3.4e-1 -0.115 3.0e-1 24 Click to see details
GSE42095 Differentiated embryonic stem cells 0.087 3.5e-1 0.107 3.1e-1 23 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.383 0 -0.306 0.02 49 Click to see details
STAD 0.408 0.01 0.422 0.01 32 Click to see details
BRCA -0.236 0.02 -0.239 0.01 84 Click to see details
COAD -0.744 0.02 -0.762 0.01 8 Click to see details
PCPG -0.991 0.04 -0.500 0.33 3 Click to see details
HNSC 0.254 0.05 0.237 0.07 42 Click to see details
ESCA -0.431 0.09 -0.318 0.17 11 Click to see details
LUAD -0.391 0.1 -0.350 0.13 12 Click to see details
PAAD -0.787 0.11 -0.600 0.2 4 Click to see details
CHOL -0.406 0.14 -0.267 0.24 9 Click to see details
LUSC -0.17 0.15 -0.164 0.16 38 Click to see details
CESC -0.881 0.16 -0.500 0.33 3 Click to see details
KIRP 0.172 0.17 0.243 0.09 32 Click to see details
UCEC -0.224 0.18 -0.298 0.11 19 Click to see details
THCA -0.064 0.32 -0.086 0.26 59 Click to see details
KIRC -0.033 0.39 -0.048 0.35 68 Click to see details
PRAD -0.028 0.42 -0.024 0.43 50 Click to see details
BLCA -0.025 0.46 -0.020 0.47 18 Click to see details
KICH 0.014 0.47 0.215 0.15 25 Click to see details
KICH 0.014 0.47 0.215 0.15 25 Click to see details
KICH 0.014 0.47 0.215 0.15 25 Click to see details
88 hsa-miR-664a-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT035824 HIAT1 major facilitator superfamily domain containing 14A 1 1
MIRT035826 FUS FUS RNA binding protein 1 1
MIRT069432 SIVA1 SIVA1 apoptosis inducing factor 2 2
MIRT071494 CALM1 calmodulin 1 2 2
MIRT100410 HSPA1B heat shock protein family A (Hsp70) member 1B 2 2
MIRT143469 CHD9 chromodomain helicase DNA binding protein 9 2 2
MIRT191113 ARF6 ADP ribosylation factor 6 2 2
MIRT235584 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT339131 ARID1A AT-rich interaction domain 1A 2 2
MIRT437450 MAT1A methionine adenosyltransferase 1A 1 1
MIRT442234 BTD biotinidase 2 2
MIRT443321 SLC35G1 solute carrier family 35 member G1 2 2
MIRT443769 HLF HLF, PAR bZIP transcription factor 2 2
MIRT444352 KIAA1211 KIAA1211 2 2
MIRT456348 OLIG3 oligodendrocyte transcription factor 3 2 8
MIRT458866 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT466169 TMED5 transmembrane p24 trafficking protein 5 2 2
MIRT470445 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 6
MIRT471524 PCGF3 polycomb group ring finger 3 2 6
MIRT477744 EDN1 endothelin 1 2 2
MIRT482885 CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 2 2
MIRT496336 PTPRT protein tyrosine phosphatase, receptor type T 2 2
MIRT497703 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 2
MIRT499068 CTBP1 C-terminal binding protein 1 2 4
MIRT500296 ZNF667 zinc finger protein 667 2 8
MIRT500506 ZBTB34 zinc finger and BTB domain containing 34 2 8
MIRT501964 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT505457 SUB1 SUB1 homolog, transcriptional regulator 2 4
MIRT505955 RAN RAN, member RAS oncogene family 2 6
MIRT507512 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT512953 MKI67 marker of proliferation Ki-67 2 2
MIRT520450 TSPAN2 tetraspanin 2 2 6
MIRT525997 MAGEL2 MAGE family member L2 2 2
MIRT526424 ZNF695 zinc finger protein 695 2 2
MIRT527364 KRTAP13-2 keratin associated protein 13-2 2 2
MIRT529612 H1F0 H1 histone family member 0 2 2
MIRT529811 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT530971 EXO5 exonuclease 5 2 4
MIRT531294 WNT7A Wnt family member 7A 2 2
MIRT531870 POF1B premature ovarian failure, 1B 2 2
MIRT532116 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT533534 TPR translocated promoter region, nuclear basket protein 2 2
MIRT545934 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546649 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT548063 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT548288 FAM3C family with sequence similarity 3 member C 2 4
MIRT551018 SPPL3 signal peptide peptidase like 3 2 2
MIRT551139 ZNF678 zinc finger protein 678 2 2
MIRT552398 ZNF487P zinc finger protein 487 1 1
MIRT555640 PHIP pleckstrin homology domain interacting protein 2 4
MIRT556267 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT558864 CD2AP CD2 associated protein 2 2
MIRT559239 BEND4 BEN domain containing 4 2 2
MIRT559438 ARSJ arylsulfatase family member J 2 2
MIRT559793 ZNF415 zinc finger protein 415 2 2
MIRT562572 CBX6 chromobox 6 2 2
MIRT562741 ZNF83 zinc finger protein 83 2 2
MIRT564737 ZNF23 zinc finger protein 23 2 2
MIRT565174 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT566301 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT571656 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT610720 NAV2 neuron navigator 2 2 2
MIRT611486 ADCYAP1R1 ADCYAP receptor type I 2 4
MIRT617118 KANK2 KN motif and ankyrin repeat domains 2 2 2
MIRT617836 SIGLEC10 sialic acid binding Ig like lectin 10 2 2
MIRT636145 VLDLR very low density lipoprotein receptor 2 2
MIRT638060 YAE1D1 Yae1 domain containing 1 2 4
MIRT640159 CDK13 cyclin dependent kinase 13 2 2
MIRT644257 WEE2 WEE1 homolog 2 2 2
MIRT646838 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT653074 ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2 2
MIRT657671 GPR26 G protein-coupled receptor 26 2 2
MIRT660601 AP3M2 adaptor related protein complex 3 mu 2 subunit 2 2
MIRT668908 CREB1 cAMP responsive element binding protein 1 2 2
MIRT672685 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT680977 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682271 RS1 retinoschisin 1 2 2
MIRT702058 RNMT RNA guanine-7 methyltransferase 2 2
MIRT707786 UNK unkempt family zinc finger 2 2
MIRT709238 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT710119 MED23 mediator complex subunit 23 2 2
MIRT710675 ADAP2 ArfGAP with dual PH domains 2 2 2
MIRT712884 NIPBL NIPBL, cohesin loading factor 2 2
MIRT719015 HPGD 15-hydroxyprostaglandin dehydrogenase 2 2
MIRT723323 COLEC10 collectin subfamily member 10 2 2
MIRT724947 TXNL1 thioredoxin like 1 2 2
MIRT725535 EN2 engrailed homeobox 2 2 2
MIRT734156 FHL1 four and a half LIM domains 1 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-664a Plx-4720 24180719 NSC757438 resistant High Thyroid Cancer cell line (8505c, BCPAP)
hsa-mir-664a Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-664a Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-miR-664a-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (HT-29)
hsa-miR-664a-3p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (RKO)
hsa-miR-664a-3p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (Huh-7)
hsa-miR-664a-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC7901)
hsa-miR-664a-3p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-664a-3p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-664a-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375)
hsa-miR-664a-3p Fluorouracil 3385 NSC19893 approved resistant High Colorectal Cancer cell line (HCT-116)
hsa-miR-664a-3p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-664a-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-664a-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-664a-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-664a-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-664a-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-miR-664a-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-664a-3p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-664a-3p Fluorouracil 3385 NSC19893 approved resistant cell line (HCT15)
hsa-miR-664a-3p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-664a-3p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-664a-3p Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-664a-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-664a-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-664a-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-664a-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-664a-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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