miRTarBase - #MIRT444802


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pre-miRNA Information
pre-miRNA hsa-mir-100   
Genomic Coordinates chr11: 122152229 - 122152308
Synonyms MIRN100, miR-100, MIR100
Description Homo sapiens miR-100 stem-loop
Comment This sequence is localised to chromosome 11 and was named mir-100-11 in reference .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-100-3p
Sequence 48| CAAGCUUGUAUCUAUAGGUAUG |69
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 11 - 122152259 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs773933142 2 dbSNP
rs1321972926 4 dbSNP
rs770590792 7 dbSNP
rs1388368183 9 dbSNP
rs909526986 14 dbSNP
rs749039221 15 dbSNP
rs530428149 17 dbSNP
rs775253529 17 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TMEM251   
Synonyms C14orf109
Description transmembrane protein 251
Transcript NM_001098621   
Other Transcripts NM_015676   
Expression
Putative miRNA Targets on TMEM251
3'UTR of TMEM251
(miRNA target sites are highlighted)		 
>TMEM251|NM_001098621|3'UTR
   1 AATCAGTCACCGTTTTTTCCCTACGATTACAAAACTGCCAGTCCTATATGGAGTCTGATCACAAGACTGCAGTTTCTTCA
  81 CAGATCTCAGGAAGTTGTCGTGGGGCAGAGGCTTTTTAAAAACATGTGATTAGGGAGCTATCTTTATCTGAATAATAACG
 161 AATTTTTAGGTAAAACCTGAGATAGAGTACTACAAAATCATGTTGATGACTTCAGATTTTGGAAGTTAAATCATGTCTGT
 241 TATTTGCATTCTTTAGAAACTTGACTAAGTACCTGAATTCATATTTCTATTCTACTGTGCAACATAGTGATGATTCAGAA
 321 ATTTTTCCTTTGGGGAAAAAAATGAATATGAACATTTCCATTGTGTTAAGTGTAAAAAGGTCCAGACATGATCATAAAAT
 401 TTAAATTTTATACAATTAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guauGGAUAU--------CUA-UGUUC-GAac 5'
              ||||||        ||| ||||| ||  
Target 5' cagtCCTATATGGAGTCTGATCACAAGACTgc 3'
 39 - 70 108.00 -11.50
2 
miRNA  3' guauggauaucuaugUUCGAAc 5'
                         |:|||| 
Target 5' gttgtcgtggggcagAGGCTTt 3'
 94 - 115 104.00 -7.60
3 
miRNA  3' guAUGGAU-AUCUAUGUUCGAAc 5'
            |::||: ||  |:||  ||| 
Target 5' caTGTCTGTTATTTGCATTCTTt 3'
 232 - 254 96.00 -9.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30133289 7 COSMIC
COSN26999008 19 COSMIC
COSN26999009 19 COSMIC
COSN30142115 26 COSMIC
COSN30118221 70 COSMIC
COSN30101364 103 COSMIC
COSN30492153 130 COSMIC
COSN30140610 160 COSMIC
COSN30120868 161 COSMIC
COSN31515314 162 COSMIC
COSN30187630 182 COSMIC
COSN31480578 200 COSMIC
COSN31485192 214 COSMIC
COSN30119226 231 COSMIC
COSN30534824 233 COSMIC
COSN30114253 398 COSMIC
COSN22097685 659 COSMIC
COSN16638185 770 COSMIC
COSN17714415 984 COSMIC
COSN21695602 1357 COSMIC
COSN5210944 1413 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs745564025 9 dbSNP
rs1310020581 11 dbSNP
rs1344625828 12 dbSNP
rs1198918869 13 dbSNP
rs769224822 15 dbSNP
rs1299247508 17 dbSNP
rs774992621 20 dbSNP
rs1197706698 21 dbSNP
rs762504169 25 dbSNP
rs764576645 26 dbSNP
rs774884285 29 dbSNP
rs200503787 31 dbSNP
rs1393933645 35 dbSNP
rs762065266 36 dbSNP
rs767949879 46 dbSNP
rs1217359836 49 dbSNP
rs1317090743 55 dbSNP
rs566463433 56 dbSNP
rs554355546 59 dbSNP
rs1225803927 66 dbSNP
rs982975754 84 dbSNP
rs1434989403 91 dbSNP
rs1267664488 96 dbSNP
rs981725194 100 dbSNP
rs764326014 118 dbSNP
rs369313359 120 dbSNP
rs199810758 124 dbSNP
rs908703089 124 dbSNP
rs1038612071 141 dbSNP
rs1222823291 143 dbSNP
rs1267708894 147 dbSNP
rs116029458 149 dbSNP
rs1184024519 153 dbSNP
rs1427816722 154 dbSNP
rs916139706 156 dbSNP
rs752334828 160 dbSNP
rs948710831 161 dbSNP
rs1187799510 163 dbSNP
rs1261735416 170 dbSNP
rs1361224941 180 dbSNP
rs1292924305 192 dbSNP
rs1049724968 200 dbSNP
rs1306215052 215 dbSNP
rs907287231 216 dbSNP
rs1382779690 234 dbSNP
rs887940571 236 dbSNP
rs758183928 244 dbSNP
rs1039057182 246 dbSNP
rs200715503 247 dbSNP
rs1406970351 248 dbSNP
rs901861310 250 dbSNP
rs1366469257 260 dbSNP
rs1163936774 266 dbSNP
rs892282558 270 dbSNP
rs1172441438 274 dbSNP
rs997899262 285 dbSNP
rs1022186935 290 dbSNP
rs543135912 293 dbSNP
rs899731711 297 dbSNP
rs1269185328 306 dbSNP
rs1195530002 313 dbSNP
rs1372335575 335 dbSNP
rs147298582 336 dbSNP
rs554630763 336 dbSNP
rs777618225 347 dbSNP
rs1029706102 354 dbSNP
rs1020891442 356 dbSNP
rs955191410 358 dbSNP
rs982924425 360 dbSNP
rs556605980 366 dbSNP
rs1363978787 372 dbSNP
rs533609211 373 dbSNP
rs1389955968 375 dbSNP
rs1394052637 380 dbSNP
rs1299722184 386 dbSNP
rs74984385 389 dbSNP
rs962888139 394 dbSNP
rs959188492 412 dbSNP
rs990570622 425 dbSNP
rs556201455 427 dbSNP
rs771017064 428 dbSNP
rs1180635949 439 dbSNP
rs1416994602 444 dbSNP
rs1253074490 455 dbSNP
rs372910344 456 dbSNP
rs192397446 457 dbSNP
rs541698597 458 dbSNP
rs1461227492 471 dbSNP
rs1384057298 473 dbSNP
rs1205568776 481 dbSNP
rs1324369889 486 dbSNP
rs916173825 487 dbSNP
rs1237127861 497 dbSNP
rs948910579 498 dbSNP
rs1308834135 503 dbSNP
rs970431675 510 dbSNP
rs1289999342 516 dbSNP
rs1334610585 526 dbSNP
rs928617743 528 dbSNP
rs1406151391 530 dbSNP
rs1157530592 533 dbSNP
rs972785784 544 dbSNP
rs561485929 561 dbSNP
rs1365216413 566 dbSNP
rs1182920163 584 dbSNP
rs77126471 588 dbSNP
rs985007354 595 dbSNP
rs1241757126 598 dbSNP
rs1485239482 598 dbSNP
rs1283616256 612 dbSNP
rs1462194455 612 dbSNP
rs893196911 613 dbSNP
rs10133344 634 dbSNP
rs1261545658 639 dbSNP
rs77387017 642 dbSNP
rs1381759640 646 dbSNP
rs114666512 647 dbSNP
rs1182755391 649 dbSNP
rs899764990 650 dbSNP
rs552536771 651 dbSNP
rs145858927 654 dbSNP
rs923337439 656 dbSNP
rs1398473784 659 dbSNP
rs933399176 663 dbSNP
rs570285588 665 dbSNP
rs1029365622 667 dbSNP
rs1411560308 669 dbSNP
rs1160097458 673 dbSNP
rs572408742 674 dbSNP
rs115760200 679 dbSNP
rs116076713 682 dbSNP
rs1001228668 683 dbSNP
rs1053663369 691 dbSNP
rs567931387 695 dbSNP
rs1357616323 696 dbSNP
rs1289281099 697 dbSNP
rs1247938495 699 dbSNP
rs1356903288 701 dbSNP
rs1012058921 703 dbSNP
rs1024747282 713 dbSNP
rs1379562961 730 dbSNP
rs1403921435 731 dbSNP
rs1363368338 736 dbSNP
rs1395311822 743 dbSNP
rs982087182 747 dbSNP
rs1406336681 748 dbSNP
rs1307232554 750 dbSNP
rs970912581 751 dbSNP
rs1419349927 754 dbSNP
rs1166654864 763 dbSNP
rs576032535 764 dbSNP
rs993924400 765 dbSNP
rs111381620 769 dbSNP
rs201913768 770 dbSNP
rs934677753 770 dbSNP
rs556808426 771 dbSNP
rs1224365191 773 dbSNP
rs1451970048 783 dbSNP
rs1272099902 784 dbSNP
rs914667488 788 dbSNP
rs750385164 791 dbSNP
rs1341437838 796 dbSNP
rs749384369 800 dbSNP
rs947437974 803 dbSNP
rs1461721910 812 dbSNP
rs1222400181 816 dbSNP
rs541328271 818 dbSNP
rs576862193 819 dbSNP
rs564325275 822 dbSNP
rs1175738828 826 dbSNP
rs1051470221 838 dbSNP
rs1200406792 842 dbSNP
rs1178047107 843 dbSNP
rs1232061493 846 dbSNP
rs909441180 848 dbSNP
rs539120836 850 dbSNP
rs964870115 857 dbSNP
rs1272242492 861 dbSNP
rs974907675 867 dbSNP
rs1004292159 874 dbSNP
rs1258649026 876 dbSNP
rs866122208 890 dbSNP
rs1417516855 897 dbSNP
rs1178688068 901 dbSNP
rs552934840 903 dbSNP
rs923448203 916 dbSNP
rs1284711048 918 dbSNP
rs768803041 927 dbSNP
rs138336214 931 dbSNP
rs1278105310 942 dbSNP
rs1356689923 942 dbSNP
rs1444841786 944 dbSNP
rs200951165 946 dbSNP
rs1297919424 949 dbSNP
rs923938428 953 dbSNP
rs1372161228 961 dbSNP
rs1408362104 961 dbSNP
rs995246400 961 dbSNP
rs936651007 964 dbSNP
rs1284712388 972 dbSNP
rs1175211394 973 dbSNP
rs1053716014 974 dbSNP
rs970196314 981 dbSNP
rs1238638592 984 dbSNP
rs1182902257 985 dbSNP
rs1323620037 989 dbSNP
rs1003021095 997 dbSNP
rs774499069 1000 dbSNP
rs1261154503 1002 dbSNP
rs1315906383 1003 dbSNP
rs10135777 1008 dbSNP
rs1012151932 1015 dbSNP
rs377092203 1018 dbSNP
rs1314861504 1020 dbSNP
rs1046297220 1023 dbSNP
rs1205001255 1025 dbSNP
rs1232029289 1030 dbSNP
rs1479789654 1033 dbSNP
rs906363768 1035 dbSNP
rs1343590016 1039 dbSNP
rs1161553069 1040 dbSNP
rs1420607950 1041 dbSNP
rs1201847109 1042 dbSNP
rs994326906 1047 dbSNP
rs1025359013 1048 dbSNP
rs1480135583 1053 dbSNP
rs1258205228 1055 dbSNP
rs561546134 1065 dbSNP
rs952498508 1070 dbSNP
rs1005153871 1071 dbSNP
rs1410951911 1072 dbSNP
rs1239927936 1073 dbSNP
rs1170204428 1081 dbSNP
rs1354022280 1082 dbSNP
rs1291448982 1103 dbSNP
rs1353105191 1111 dbSNP
rs914574416 1120 dbSNP
rs1407682770 1123 dbSNP
rs1304549042 1124 dbSNP
rs1345649288 1125 dbSNP
rs1017880232 1132 dbSNP
rs1272533430 1144 dbSNP
rs1341394510 1151 dbSNP
rs1215032382 1153 dbSNP
rs1272102485 1154 dbSNP
rs974787035 1159 dbSNP
rs1365216216 1160 dbSNP
rs964962691 1168 dbSNP
rs974955135 1169 dbSNP
rs1269892204 1174 dbSNP
rs1490235382 1176 dbSNP
rs1197364764 1177 dbSNP
rs1243857619 1179 dbSNP
rs1476059746 1185 dbSNP
rs921994886 1195 dbSNP
rs772365272 1196 dbSNP
rs1370050552 1203 dbSNP
rs1417864221 1209 dbSNP
rs1427909153 1214 dbSNP
rs773601460 1219 dbSNP
rs1050911675 1223 dbSNP
rs1164553994 1230 dbSNP
rs1488385657 1235 dbSNP
rs1365843439 1240 dbSNP
rs2532894 1256 dbSNP
rs912470304 1258 dbSNP
rs1030954775 1263 dbSNP
rs1489670721 1263 dbSNP
rs369416873 1265 dbSNP
rs954860256 1271 dbSNP
rs1423536644 1274 dbSNP
rs1266465278 1275 dbSNP
rs1321028650 1277 dbSNP
rs144326408 1283 dbSNP
rs939950246 1286 dbSNP
rs1306305241 1292 dbSNP
rs1037138639 1294 dbSNP
rs1219349141 1299 dbSNP
rs1431481090 1307 dbSNP
rs978588957 1309 dbSNP
rs1269493858 1325 dbSNP
rs183270965 1330 dbSNP
rs936673595 1332 dbSNP
rs989505080 1350 dbSNP
rs995277617 1351 dbSNP
rs916577193 1352 dbSNP
rs1208273324 1357 dbSNP
rs1044187045 1362 dbSNP
rs905583358 1367 dbSNP
rs563675667 1371 dbSNP
rs1035824392 1381 dbSNP
rs1477865961 1387 dbSNP
rs1428073817 1388 dbSNP
rs1046273415 1390 dbSNP
rs1434598079 1392 dbSNP
rs956530949 1395 dbSNP
rs1010482146 1396 dbSNP
rs906367494 1405 dbSNP
rs1240887661 1408 dbSNP
rs929799656 1413 dbSNP
rs760895653 1414 dbSNP
rs1184598890 1433 dbSNP
rs1021611104 1434 dbSNP
rs1443696367 1435 dbSNP
rs1331941038 1439 dbSNP
rs1047272205 1443 dbSNP
rs1161093880 1454 dbSNP
rs1301659126 1463 dbSNP
rs1386556029 1468 dbSNP
rs766899592 1472 dbSNP
rs888229396 1475 dbSNP
rs186399120 1476 dbSNP
rs1371007629 1477 dbSNP
rs563826961 1478 dbSNP
rs1404697348 1489 dbSNP
rs1173691402 1496 dbSNP
rs1017927808 1499 dbSNP
rs1377862638 1500 dbSNP
rs1454451593 1508 dbSNP
rs899502876 1509 dbSNP
rs759059604 1511 dbSNP
rs922025833 1520 dbSNP
rs954776039 1525 dbSNP
rs749064986 1528 dbSNP
rs1315533527 1543 dbSNP
rs1345908880 1551 dbSNP
rs1030547790 1574 dbSNP
rs955057672 1580 dbSNP
rs978260020 1592 dbSNP
rs1031569189 1596 dbSNP
rs958137678 1601 dbSNP
rs1311250148 1613 dbSNP
rs1351601863 1616 dbSNP
rs1204635243 1623 dbSNP
rs1334057881 1632 dbSNP
rs1397280191 1637 dbSNP
rs559720566 1644 dbSNP
rs1463068035 1645 dbSNP
rs972625896 1649 dbSNP
rs1204839767 1663 dbSNP
rs189962623 1668 dbSNP
rs919818625 1679 dbSNP
rs948003437 1681 dbSNP
rs982451930 1694 dbSNP
rs1241848344 1698 dbSNP
rs927881329 1700 dbSNP
rs555701347 1703 dbSNP
rs929866392 1709 dbSNP
rs1203595267 1729 dbSNP
rs1489418902 1732 dbSNP
rs144414275 1735 dbSNP
rs1240624323 1737 dbSNP
rs905612501 1738 dbSNP
rs1046923866 1761 dbSNP
rs34954547 1769 dbSNP
rs1057492890 1775 dbSNP
rs888274785 1781 dbSNP
rs941150648 1789 dbSNP
rs1157510006 1790 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guauggauaucuauGUUCGAAc 5'
                        ||||||| 
Target 5' -------------uCAAGCUUu 3'
 		1 - 9
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000415050.2 | 3UTR | UCAAGCUUUCCUCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
107 hsa-miR-100-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT105690 LEPROTL1 leptin receptor overlapping transcript like 1 2 2
MIRT151558 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 4
MIRT167753 SGK1 serum/glucocorticoid regulated kinase 1 2 2
MIRT195380 CBFB core-binding factor beta subunit 2 2
MIRT283995 DNAJA2 DnaJ heat shock protein family (Hsp40) member A2 2 2
MIRT317145 E2F3 E2F transcription factor 3 2 4
MIRT380785 ZFP3 ZFP3 zinc finger protein 2 2
MIRT380927 ZNF264 zinc finger protein 264 2 2
MIRT441600 ABCB5 ATP binding cassette subfamily B member 5 2 6
MIRT443896 NUDT3 nudix hydrolase 3 2 4
MIRT444030 GREM1 gremlin 1, DAN family BMP antagonist 2 4
MIRT444112 CEPT1 choline/ethanolamine phosphotransferase 1 2 2
MIRT444169 ZNF701 zinc finger protein 701 2 2
MIRT444366 TIMM8B translocase of inner mitochondrial membrane 8 homolog B 2 2
MIRT444371 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT444517 ZNF525 zinc finger protein 525 2 2
MIRT444525 CNIH4 cornichon family AMPA receptor auxiliary protein 4 2 2
MIRT444529 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT444537 PHKB phosphorylase kinase regulatory subunit beta 2 2
MIRT444702 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT444717 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT444730 TMC7 transmembrane channel like 7 2 2
MIRT444777 NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2 2
MIRT444802 TMEM251 transmembrane protein 251 2 2
MIRT444995 LRRC57 leucine rich repeat containing 57 2 2
MIRT445073 C16orf87 chromosome 16 open reading frame 87 2 2
MIRT445250 SEMA5A semaphorin 5A 2 2
MIRT445336 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT445426 TPT1 tumor protein, translationally-controlled 1 2 4
MIRT445469 TRIM13 tripartite motif containing 13 2 2
MIRT445646 NPY4R neuropeptide Y receptor Y4 2 2
MIRT445759 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT445838 SRSF11 serine and arginine rich splicing factor 11 2 2
MIRT445868 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT446368 STX16 syntaxin 16 2 2
MIRT446444 THYN1 thymocyte nuclear protein 1 2 2
MIRT446593 TASP1 taspase 1 2 2
MIRT446926 SRSF7 serine and arginine rich splicing factor 7 2 2
MIRT447121 SLFN5 schlafen family member 5 2 2
MIRT447196 CDCP1 CUB domain containing protein 1 2 2
MIRT447358 STOM stomatin 2 2
MIRT447361 FAM161B family with sequence similarity 161 member B 2 2
MIRT447374 NUP205 nucleoporin 205 2 2
MIRT447467 OSMR oncostatin M receptor 2 2
MIRT447606 MRPL3 mitochondrial ribosomal protein L3 2 2
MIRT447682 ASPA aspartoacylase 2 2
MIRT447715 ERP44 endoplasmic reticulum protein 44 2 2
MIRT447814 EMX1 empty spiracles homeobox 1 2 2
MIRT447855 RRP8 ribosomal RNA processing 8 2 4
MIRT447866 KIAA1244 ARFGEF family member 3 1 1
MIRT447890 STRIP2 striatin interacting protein 2 2 2
MIRT447916 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT447935 DUSP4 dual specificity phosphatase 4 2 2
MIRT448813 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT448927 CKS1B CDC28 protein kinase regulatory subunit 1B 2 2
MIRT449105 CREBRF CREB3 regulatory factor 2 2
MIRT449216 ZNHIT3 zinc finger HIT-type containing 3 2 2
MIRT449336 ACTBL2 actin, beta like 2 2 2
MIRT449675 SOX3 SRY-box 3 2 2
MIRT449724 POU2F1 POU class 2 homeobox 1 2 2
MIRT449768 PRAMEF7 PRAME family member 7 2 2
MIRT449804 PRAMEF8 PRAME family member 8 2 2
MIRT449850 BCL2L13 BCL2 like 13 2 2
MIRT449866 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT450067 SYT9 synaptotagmin 9 2 2
MIRT450197 ZHX3 zinc fingers and homeoboxes 3 2 2
MIRT450386 TENM4 teneurin transmembrane protein 4 2 2
MIRT450435 PAX8 paired box 8 2 2
MIRT450716 PVRL3 nectin cell adhesion molecule 3 2 2
MIRT495906 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT497543 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT497630 ZNF576 zinc finger protein 576 2 2
MIRT497756 OXGR1 oxoglutarate receptor 1 2 2
MIRT498072 SLC25A12 solute carrier family 25 member 12 2 2
MIRT500542 XPO4 exportin 4 2 4
MIRT500848 SYPL1 synaptophysin like 1 2 4
MIRT511621 HIST1H3J histone cluster 1 H3 family member j 2 4
MIRT513745 PKNOX1 PBX/knotted 1 homeobox 1 2 2
MIRT535077 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT543133 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT544518 GTF2E2 general transcription factor IIE subunit 2 2 2
MIRT544666 MED19 mediator complex subunit 19 2 2
MIRT545407 KIAA1715 lunapark, ER junction formation factor 2 2
MIRT547569 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT548767 CNN3 calponin 3 2 2
MIRT551009 TRIM4 tripartite motif containing 4 2 2
MIRT555077 PURG purine rich element binding protein G 2 2
MIRT560753 ZNF616 zinc finger protein 616 2 2
MIRT563752 FOXO3 forkhead box O3 2 2
MIRT565531 SON SON DNA binding protein 2 2
MIRT613933 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT614433 TAZ tafazzin 2 2
MIRT622520 RAP2A RAP2A, member of RAS oncogene family 2 2
MIRT626037 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT648459 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT654982 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 4
MIRT689103 ZBTB25 zinc finger and BTB domain containing 25 2 2
MIRT704259 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT711194 CXCL3 C-X-C motif chemokine ligand 3 2 2
MIRT713315 VLDLR very low density lipoprotein receptor 2 2
MIRT717266 BMPR2 bone morphogenetic protein receptor type 2 4 2
MIRT718248 CCDC18 coiled-coil domain containing 18 2 2
MIRT721944 NGRN neugrin, neurite outgrowth associated 2 2
MIRT721948 IL1RAPL1 interleukin 1 receptor accessory protein like 1 2 2
MIRT734969 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 3 0
MIRT735945 NME2 NME/NM23 nucleoside diphosphate kinase 2 0 0
MIRT737404 HOXA1 homeobox A1 4 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-100 Trichostatin A (TSA) NULL 444732 Microarray human pancreatic cancer cell line BxPC-3 19112422 2009 up-regulated
miR-100 Etoposide approved 36462 Microarray Normal human fibroblasts (AG01522) 19633716 2009 down-regulated
miR-100 Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-100 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-100 Docetaxel approved 148124 Microarray human lung adenocarcinoma cells 22120675 2012 up-regulated
miR-100 Trastuzumab approved NULL Microarray BT474 cells 22384020 2012 up-regulated
miR-100 Trastuzumab approved NULL Microarray SKBR3 cells. 22384020 2012 up-regulated
miR-100 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-100 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-100 Goserelin approved 47725 Microarray prostate 22674191 2012 up-regulated
miR-100 Glucocorticoid NULL NULL Quantitative real-time PCR Eosinophilic esophagitis 22815788 2012 up-regulated
miR-100 Glucocorticoid NULL NULL TaqMan low-density array Eosinophilic esophagitis 22815788 2012 up-regulated
miR-100 Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 down-regulated
miR-100 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
miR-100 Budesonide approved 5281004 Microarray neonatal mice liver 20145010 2010 down-regulated
miR-100 Propranolol approved 4946 Quantitative real-time PCR heart 22847192 2012 up-regulated
miR-100 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 down-regulated
miR-100 Ethanol NULL 702 Microarray zebrafish embryos 22298809 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-100 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-100 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-100 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-100 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-100 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-mir-100 Androstenedione+Anastrozole resistant cell line (MCF-7)
hsa-mir-100 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-100 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-100-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-miR-100-3p Taxane 9548828 sensitive High Prostate Cancer cell line (PC-3, PR200)
hsa-miR-100-3p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia leukemia stem cells
hsa-miR-100-3p Ponatinib 24826799 NSC758487 approved sensitive High Chronic Myelogenous Leukemia leukemia stem cells
hsa-miR-100-3p Docetaxel 148124 NSC628503 approved sensitive High Prostate Cancer cell line (PC-3)
hsa-miR-100-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-100-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-100-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-100-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (A375)
hsa-miR-100-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-100-3p Palbociclib 5330286 NSC758247 approved sensitive tissue (breast cancer)
hsa-miR-100-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-100-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-100-3p Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-miR-100-3p Pegylated interferon alpha+Ribavirin resistant tissue (chronic hepatitis C)
hsa-miR-100-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (MDA-231)
hsa-miR-100-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR20)
hsa-miR-100-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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