miRTarBase - #MIRT444924


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pre-miRNA Information
pre-miRNA hsa-mir-3123   
Genomic Coordinates chr1: 241132272 - 241132346
Description Homo sapiens miR-3123 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3123
Sequence 49| CAGAGAAUUGUUUAAUC |65
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 1 + 241132323 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1453759221 1 dbSNP
rs968575171 5 dbSNP
rs979407933 9 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KIAA1522   
Synonyms -
Description KIAA1522
Transcript NM_020888   
Expression
Putative miRNA Targets on KIAA1522
3'UTR of KIAA1522
(miRNA target sites are highlighted)		 
>KIAA1522|NM_020888|3'UTR
   1 CCACCAGGCACCTCACTGGCACTGCTGACCCATCCCAGAAACACAATCTCAGGGACCCGAGCAGCTCCAAGGACGAGAGG
  81 ATACAGCAGACACAACCTAATAGAGAGGGCGCCTGCAGCCTTAACCTCCACGGCCTTCGATACTTATGCAAGCCTGGTGT
 161 TGCTCCTGTCCTCAGAGTCATCCTGCGCTCATGCCTTTTCCCGAATGGGTTCACCTCTGGCAGTTGCCGCTTCAGTCTTG
 241 GCCTTAGCCTCATCTTGAAGTGGGTAGCTGGCGGGAGAGGGTGGCTGCGCCCCCTGCTGGCCCTGAGGCTGCAGAGTTGG
 321 GAGCAGGACACCTCACCTGAGTTTCATTTTTTTTCATGTCCAAACCATGCACATACTATAGTCCAGAATCAAAGCACTTT
 401 TGAAAAGTGGCTGCATGGCCATCCTCCAGGGCCCAGGAAGTTGCATTCCAAGGGCCTGTTTACATGGCAGCAGAATCCAT
 481 CCCCGGCAGTCAGCCCATAGCTTGGGACCAGTCTGTGCCCTCCTGCCCAGTCCAGTTTACTCCTCTTGGTTCCTGAAGGT
 561 GGCCAAGTCATTGTGTTCCCACAGGCTTCTCTAGGCTGGGGGCAGGTGTGGGGCTGTGGAATTCCAAAGCACAAAAGGTG
 641 CAGAGGGGATTGGCCTTCCTGTGCCTCAACTCACCAACCACCCTCCTGCCTTCCAGTTCTGCCAGGTGCTCCATGCTGGG
 721 GACAAGTAGGAGACTGCCAGGGCCCAAAGAAATGGGTGAGCAGTAGAGTCATCTCGGGGCACTTGGCAGTGTCAAGCACC
 801 TGCCCCTTGCCTCCTTGACCACACTGGGGTGGGTGGGCCCCCAGCACTTCAGAGGCAGGAGCCTTTGGGCTGAGCAAGCA
 881 CTGAGGAGGTGGATGGAAGGGAGCATCTGGAGGGGGGGAGCTTCCTTGAGCAGTGGGCCCAGGCCTGGCCCTCCACACTT
 961 CATTCTCTGACCTTTCTCTCTCCTCATTTCGGTGCATGTCCTTTCTGCAGCTGCCTTTCAGCACAGGTGGTTCCACTGGG
1041 GGCAGCTAACGCTGAGTGACAAGGATGGGAAGCCACAGGTGCATTTTACTCAAGTCTTCTCTAGTCAATGAGGGGCACCC
1121 AGTGCTTCTAGGGCAGGCTGGGTGGTGGTCCCCTAGGTATCAGCCTCTCTTACTGTACTCTCCGGGAATGTTAACCTTTC
1201 TATTTTCAGCCTGTGCCACCTGTCTAGGCAAGCTGGCTTCCCCATTGGCCCCTGTGGGTCCACAGCAGCGTGGCTGCCCC
1281 CCAGGGCCACCGCTTCTTTCTTGATCCTCTTTCCTTAACAGTGACTTGGGCTTGAGTCTGGCAAGGAACCTTGCTTTTAG
1361 CTTCACCACCAAGGAGAGAGGTTGACATGACCTCCCCGCCCCCTCACCAAGGCTGGGAACAGAGGGGATGTGGTGAGAGC
1441 CAGGTTCCTCTGGCCCTCTCCAGGGTGTTTTCCACTAGTCACTACTGTCTTCTCCTTGTAGCTAATCAATCAATATTCTT
1521 CCCTTGCCTGTGGGCAGTGGAGAGTGCTGCTGGGTGTACGCTGCACCTGCCCACTGAGTTGGGGAAAGAGGATAATCAGT
1601 GAGCACTGTTCTGCTCAGAGCTCCTGATCTACCCCACCCCCTAGGATCCAGGACTGGGTCAAAGCTGCATGAAACCAGGC
1681 CCTGGCAGCAACCTGGGAATGGCTGGAGGTGGGAGAGAACCTGACTTCTCTTTCCCTCTCCCTCCTCCAACATTACTGGA
1761 ACTCTATCCTGTTAGGATCTTCTGAGCTTGTTTCCCTGCTGGGTGGGACAGAGGACAAAGGAGAAGGGAGGGTCTAGAAG
1841 AGGCAGCCCTTCTTTGTCCTCTGGGGTAAATGAGCTTGACCTAGAGTAAATGGAGAGACCAAAAGCCTCTGATTTTTAAT
1921 TTCCATAAAATGTTAGAAGTATATATATACATATATATATTTCTTTAAATTTTTGAGTCTTTGATATGTCTAAAAATCCA
2001 TTCCCTCTGCCCTGAAGCCTGAGTGAGACACATGAAGAAAACTGTGTTTCATTTAAAGATGTTAATTAAATGATTGAAAC
2081 TTGAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuaauuUGU----UAAGAGAc 5'
                |||    ||||||| 
Target 5' ccctccACACTTCATTCTCTg 3'
 949 - 969 141.00 -9.30
2 
miRNA  3' cuaauuuguuAAGAGAc 5'
                    |||||| 
Target 5' tcccacaggcTTCTCTa 3'
 577 - 593 120.00 -5.60
3 
miRNA  3' cuaAUUUGU--UAAGA-GAc 5'
             |:|:||  :|||| || 
Target 5' cagTGAGCACTGTTCTGCTc 3'
 1597 - 1616 104.00 -8.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM464451 1 COSMIC
COSN30171709 23 COSMIC
COSN28861535 34 COSMIC
COSN32053702 35 COSMIC
COSN30450327 36 COSMIC
COSN30153613 49 COSMIC
COSN30161304 76 COSMIC
COSN30161300 78 COSMIC
COSN31594965 93 COSMIC
COSN30528694 190 COSMIC
COSN31532722 218 COSMIC
COSN30162881 234 COSMIC
COSN22658869 256 COSMIC
COSN31590971 308 COSMIC
COSN31552464 355 COSMIC
COSN31557665 430 COSMIC
COSN7990337 438 COSMIC
COSN30541073 444 COSMIC
COSN1103132 505 COSMIC
COSN19445902 776 COSMIC
COSN31555499 900 COSMIC
COSN31548384 1052 COSMIC
COSN8457125 1079 COSMIC
COSN31480693 1107 COSMIC
COSN31565462 1118 COSMIC
COSN26677625 1271 COSMIC
COSN31487028 1271 COSMIC
COSN7990338 1339 COSMIC
COSN32064243 1378 COSMIC
COSN31960214 1398 COSMIC
COSN31589673 1963 COSMIC
COSN31487808 1984 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs773696945 3 dbSNP
rs1212748088 12 dbSNP
rs1322475667 14 dbSNP
rs759090030 18 dbSNP
rs1391546568 19 dbSNP
rs1283689707 21 dbSNP
rs1275725073 23 dbSNP
rs775178785 30 dbSNP
rs760455182 32 dbSNP
rs879183740 33 dbSNP
rs1228823862 39 dbSNP
rs765688723 41 dbSNP
rs763725049 42 dbSNP
rs1013580367 44 dbSNP
rs753679582 45 dbSNP
rs1360309163 47 dbSNP
rs199609215 48 dbSNP
rs1282755527 55 dbSNP
rs540067536 58 dbSNP
rs558671020 59 dbSNP
rs545381517 60 dbSNP
rs1490900124 62 dbSNP
rs1214593024 64 dbSNP
rs969876432 70 dbSNP
rs1193844423 75 dbSNP
rs957458188 75 dbSNP
rs1010052642 76 dbSNP
rs1471723448 76 dbSNP
rs1162432585 78 dbSNP
rs1020513041 80 dbSNP
rs980997846 81 dbSNP
rs577034463 86 dbSNP
rs374100966 87 dbSNP
rs1339718960 97 dbSNP
rs1203796046 100 dbSNP
rs1359383687 102 dbSNP
rs965798234 102 dbSNP
rs1444040265 106 dbSNP
rs1207979707 108 dbSNP
rs766379881 111 dbSNP
rs61732475 112 dbSNP
rs1236629356 113 dbSNP
rs1244603272 117 dbSNP
rs1316130225 130 dbSNP
rs534562827 132 dbSNP
rs914125666 133 dbSNP
rs1285527406 136 dbSNP
rs921602022 139 dbSNP
rs943734185 140 dbSNP
rs953023109 142 dbSNP
rs763807624 143 dbSNP
rs373034632 148 dbSNP
rs754316401 155 dbSNP
rs910122753 156 dbSNP
rs1392247938 169 dbSNP
rs776587784 174 dbSNP
rs941550915 175 dbSNP
rs757678795 176 dbSNP
rs1037222620 180 dbSNP
rs1156466090 187 dbSNP
rs1167382908 188 dbSNP
rs918723605 190 dbSNP
rs1290111229 191 dbSNP
rs1208692257 202 dbSNP
rs143289778 203 dbSNP
rs541752574 204 dbSNP
rs1385473888 208 dbSNP
rs1332786422 210 dbSNP
rs1308814221 212 dbSNP
rs10914610 227 dbSNP
rs1241330665 229 dbSNP
rs905905820 230 dbSNP
rs1344342651 235 dbSNP
rs1001474328 239 dbSNP
rs190247919 240 dbSNP
rs746348767 242 dbSNP
rs895718241 244 dbSNP
rs545606836 246 dbSNP
rs1227269693 248 dbSNP
rs1176532927 249 dbSNP
rs1274887689 263 dbSNP
rs758433821 273 dbSNP
rs765346519 274 dbSNP
rs905158449 275 dbSNP
rs1277828957 282 dbSNP
rs753011001 286 dbSNP
rs1020123962 289 dbSNP
rs1177788882 290 dbSNP
rs868349554 291 dbSNP
rs997307192 296 dbSNP
rs1028740044 299 dbSNP
rs953054139 300 dbSNP
rs1374397881 304 dbSNP
rs1393386262 305 dbSNP
rs1246014082 313 dbSNP
rs182457886 332 dbSNP
rs1192787844 335 dbSNP
rs984458032 337 dbSNP
rs1002701516 339 dbSNP
rs1325585387 340 dbSNP
rs1196569115 341 dbSNP
rs1250528055 347 dbSNP
rs1378224749 347 dbSNP
rs1480808299 347 dbSNP
rs879575070 348 dbSNP
rs1479051601 354 dbSNP
rs1170961673 355 dbSNP
rs1479830666 356 dbSNP
rs1199488543 358 dbSNP
rs1032403924 372 dbSNP
rs1016322461 374 dbSNP
rs1236583844 376 dbSNP
rs963007469 379 dbSNP
rs1458274534 382 dbSNP
rs1161791267 386 dbSNP
rs528582736 397 dbSNP
rs1367157618 398 dbSNP
rs1405697848 404 dbSNP
rs1381259568 407 dbSNP
rs1323819343 416 dbSNP
rs1347372660 421 dbSNP
rs918793505 425 dbSNP
rs1216746534 428 dbSNP
rs950211141 430 dbSNP
rs373290315 434 dbSNP
rs1294720699 441 dbSNP
rs1021184584 443 dbSNP
rs1206277653 448 dbSNP
rs965596965 456 dbSNP
rs976419888 458 dbSNP
rs1433667476 470 dbSNP
rs1282150058 482 dbSNP
rs920935368 485 dbSNP
rs561927549 494 dbSNP
rs984293568 498 dbSNP
rs1265965222 512 dbSNP
rs1420774779 519 dbSNP
rs909621277 526 dbSNP
rs939874311 539 dbSNP
rs75823208 543 dbSNP
rs927360202 544 dbSNP
rs937402414 572 dbSNP
rs1358736982 582 dbSNP
rs1399405373 583 dbSNP
rs1288226735 584 dbSNP
rs1054474009 603 dbSNP
rs1362553659 609 dbSNP
rs1216174640 613 dbSNP
rs1453600770 617 dbSNP
rs1310290113 619 dbSNP
rs1036863822 621 dbSNP
rs550971193 626 dbSNP
rs1246304567 627 dbSNP
rs1293415159 628 dbSNP
rs1487030462 634 dbSNP
rs1196819037 637 dbSNP
rs917206163 638 dbSNP
rs893091288 640 dbSNP
rs1268324173 663 dbSNP
rs1473183465 673 dbSNP
rs945986737 678 dbSNP
rs1044297011 679 dbSNP
rs1165706547 681 dbSNP
rs905209870 697 dbSNP
rs1042024778 703 dbSNP
rs901711451 706 dbSNP
rs1461834468 719 dbSNP
rs1410148729 721 dbSNP
rs1345753110 724 dbSNP
rs1432838777 728 dbSNP
rs747032661 740 dbSNP
rs1028770697 755 dbSNP
rs188154947 759 dbSNP
rs1316787079 764 dbSNP
rs540009971 771 dbSNP
rs1222751483 777 dbSNP
rs552007081 781 dbSNP
rs758077903 789 dbSNP
rs1054307596 792 dbSNP
rs1392412182 802 dbSNP
rs1403292589 806 dbSNP
rs1301955257 807 dbSNP
rs1350603413 825 dbSNP
rs1194494116 829 dbSNP
rs1243000949 835 dbSNP
rs570520237 837 dbSNP
rs768934282 838 dbSNP
rs1015940868 839 dbSNP
rs1021069997 840 dbSNP
rs965482080 842 dbSNP
rs1410301764 843 dbSNP
rs148313831 845 dbSNP
rs1174208444 847 dbSNP
rs1267047605 851 dbSNP
rs1358700791 852 dbSNP
rs1333673420 853 dbSNP
rs1441050566 853 dbSNP
rs1279728331 857 dbSNP
rs192384034 871 dbSNP
rs953874120 875 dbSNP
rs983788407 885 dbSNP
rs1483432936 887 dbSNP
rs1184878025 892 dbSNP
rs1324879488 894 dbSNP
rs909663191 895 dbSNP
rs530173166 902 dbSNP
rs972442998 905 dbSNP
rs1419060833 907 dbSNP
rs917090856 910 dbSNP
rs1044719235 912 dbSNP
rs765443677 912 dbSNP
rs927218597 913 dbSNP
rs535464249 914 dbSNP
rs556800806 915 dbSNP
rs998298639 916 dbSNP
rs927436952 917 dbSNP
rs1346748358 918 dbSNP
rs1029017761 935 dbSNP
rs937448877 943 dbSNP
rs1276787355 954 dbSNP
rs1431101757 956 dbSNP
rs1339158363 957 dbSNP
rs1196736377 959 dbSNP
rs575186934 959 dbSNP
rs1275463292 963 dbSNP
rs1305707493 972 dbSNP
rs1450053170 973 dbSNP
rs954319284 975 dbSNP
rs1269725726 980 dbSNP
rs751407915 980 dbSNP
rs990598935 982 dbSNP
rs914618973 986 dbSNP
rs545549717 987 dbSNP
rs1005665572 990 dbSNP
rs1314563846 991 dbSNP
rs563950756 992 dbSNP
rs960993289 999 dbSNP
rs1041686090 1001 dbSNP
rs1302086050 1008 dbSNP
rs1243983603 1011 dbSNP
rs755972852 1014 dbSNP
rs530134278 1016 dbSNP
rs1316917701 1017 dbSNP
rs1326359320 1022 dbSNP
rs1228663812 1026 dbSNP
rs1272266532 1026 dbSNP
rs1207361408 1028 dbSNP
rs1357682209 1030 dbSNP
rs972495426 1044 dbSNP
rs184284018 1051 dbSNP
rs1490864396 1052 dbSNP
rs1214522533 1065 dbSNP
rs916972856 1070 dbSNP
rs1446320358 1078 dbSNP
rs971248903 1091 dbSNP
rs1249737805 1092 dbSNP
rs979940722 1092 dbSNP
rs927241120 1107 dbSNP
rs1050266143 1109 dbSNP
rs143016807 1116 dbSNP
rs1005974221 1117 dbSNP
rs1327835902 1123 dbSNP
rs1258641694 1134 dbSNP
rs1381042501 1136 dbSNP
rs1452298711 1138 dbSNP
rs529256904 1141 dbSNP
rs1182526972 1143 dbSNP
rs897517759 1146 dbSNP
rs1450996909 1149 dbSNP
rs1166140159 1152 dbSNP
rs77783333 1153 dbSNP
rs1024570581 1165 dbSNP
rs1263694536 1165 dbSNP
rs1304531422 1173 dbSNP
rs78753327 1175 dbSNP
rs1003044927 1176 dbSNP
rs1243422190 1177 dbSNP
rs4642857 1181 dbSNP
rs934201906 1184 dbSNP
rs371026287 1185 dbSNP
rs767334440 1189 dbSNP
rs374350593 1191 dbSNP
rs1160810658 1192 dbSNP
rs1049915499 1195 dbSNP
rs889919281 1196 dbSNP
rs1337767318 1203 dbSNP
rs1005804394 1210 dbSNP
rs1034482787 1212 dbSNP
rs1307015110 1222 dbSNP
rs1306509003 1225 dbSNP
rs1017580675 1232 dbSNP
rs4642858 1241 dbSNP
rs1234531907 1246 dbSNP
rs1270013152 1253 dbSNP
rs1321298004 1255 dbSNP
rs959123474 1261 dbSNP
rs533677017 1267 dbSNP
rs990285663 1270 dbSNP
rs781333683 1271 dbSNP
rs1203410063 1275 dbSNP
rs1249309508 1282 dbSNP
rs967428686 1283 dbSNP
rs1249080014 1286 dbSNP
rs1183343651 1287 dbSNP
rs775105792 1291 dbSNP
rs1465944612 1293 dbSNP
rs1177721796 1297 dbSNP
rs540288446 1300 dbSNP
rs1460725072 1302 dbSNP
rs1297880451 1303 dbSNP
rs1184432012 1306 dbSNP
rs923240810 1308 dbSNP
rs1393255986 1309 dbSNP
rs1024083291 1316 dbSNP
rs971132619 1320 dbSNP
rs933234674 1325 dbSNP
rs1344915002 1334 dbSNP
rs1222864317 1340 dbSNP
rs1283777876 1344 dbSNP
rs1050297175 1345 dbSNP
rs1177697366 1346 dbSNP
rs1375842077 1349 dbSNP
rs910419203 1371 dbSNP
rs1250474455 1373 dbSNP
rs1480735025 1374 dbSNP
rs1206736996 1377 dbSNP
rs1490031933 1378 dbSNP
rs941843279 1379 dbSNP
rs1427854472 1382 dbSNP
rs1427180159 1383 dbSNP
rs1170151651 1397 dbSNP
rs552142115 1398 dbSNP
rs1469269213 1399 dbSNP
rs376339707 1403 dbSNP
rs1301486035 1417 dbSNP
rs1365045140 1421 dbSNP
rs1034193675 1422 dbSNP
rs567066782 1428 dbSNP
rs1369633225 1436 dbSNP
rs1212626245 1438 dbSNP
rs1294553907 1440 dbSNP
rs993178295 1448 dbSNP
rs1046053614 1454 dbSNP
rs1307811893 1457 dbSNP
rs1437482887 1462 dbSNP
rs1230197641 1463 dbSNP
rs906168321 1468 dbSNP
rs116427147 1476 dbSNP
rs1387422866 1477 dbSNP
rs546360755 1479 dbSNP
rs1249010937 1485 dbSNP
rs1303561889 1492 dbSNP
rs945405502 1495 dbSNP
rs1262911316 1496 dbSNP
rs568161269 1503 dbSNP
rs978062196 1504 dbSNP
rs1384834061 1505 dbSNP
rs1321998199 1506 dbSNP
rs922726031 1516 dbSNP
rs1351592189 1519 dbSNP
rs535076116 1535 dbSNP
rs556544502 1538 dbSNP
rs1050233560 1539 dbSNP
rs1331677455 1553 dbSNP
rs1021771951 1560 dbSNP
rs1436935919 1561 dbSNP
rs1312535337 1570 dbSNP
rs1259782937 1576 dbSNP
rs538981054 1577 dbSNP
rs188786102 1580 dbSNP
rs796405750 1592 dbSNP
rs367702743 1600 dbSNP
rs1314576930 1602 dbSNP
rs111320752 1607 dbSNP
rs1266197435 1614 dbSNP
rs753479966 1617 dbSNP
rs61798844 1627 dbSNP
rs954693060 1629 dbSNP
rs1242803253 1634 dbSNP
rs1001291770 1638 dbSNP
rs986072977 1639 dbSNP
rs147449956 1641 dbSNP
rs1158306469 1646 dbSNP
rs1389267929 1650 dbSNP
rs1458657200 1657 dbSNP
rs1334423876 1658 dbSNP
rs1442707891 1661 dbSNP
rs555545684 1670 dbSNP
rs1398743258 1671 dbSNP
rs941932265 1673 dbSNP
rs1370561842 1676 dbSNP
rs1222697024 1686 dbSNP
rs1308423774 1689 dbSNP
rs8717 1698 dbSNP
rs967262436 1701 dbSNP
rs1262931947 1704 dbSNP
rs544575348 1705 dbSNP
rs975937974 1714 dbSNP
rs1295324606 1726 dbSNP
rs139846772 1729 dbSNP
rs955534436 1739 dbSNP
rs1177845943 1741 dbSNP
rs578232753 1741 dbSNP
rs929060586 1743 dbSNP
rs780306755 1753 dbSNP
rs193249693 1766 dbSNP
rs1046127294 1767 dbSNP
rs911283388 1768 dbSNP
rs1335846689 1770 dbSNP
rs537322210 1770 dbSNP
rs1352939589 1771 dbSNP
rs906241736 1781 dbSNP
rs1222415223 1785 dbSNP
rs1284062910 1790 dbSNP
rs1321912135 1791 dbSNP
rs941560317 1803 dbSNP
rs937665858 1812 dbSNP
rs768854701 1820 dbSNP
rs1223354371 1821 dbSNP
rs1283127894 1836 dbSNP
rs879457181 1838 dbSNP
rs1271227452 1839 dbSNP
rs1366327652 1843 dbSNP
rs1437441661 1849 dbSNP
rs1011803029 1855 dbSNP
rs545693074 1857 dbSNP
rs918876558 1865 dbSNP
rs1205699267 1866 dbSNP
rs1197209712 1888 dbSNP
rs1253878746 1893 dbSNP
rs930217373 1894 dbSNP
rs1174081525 1897 dbSNP
rs750734177 1900 dbSNP
rs1417006995 1903 dbSNP
rs1409030380 1907 dbSNP
rs1468590803 1911 dbSNP
rs1045974054 1919 dbSNP
rs7411174 1929 dbSNP
rs906884784 1930 dbSNP
rs1001577581 1940 dbSNP
rs903314463 1944 dbSNP
rs1414298708 1945 dbSNP
rs1424566996 1947 dbSNP
rs1332172260 1958 dbSNP
rs1439098002 1958 dbSNP
rs1165718930 1961 dbSNP
rs1268811419 1970 dbSNP
rs1363722622 1974 dbSNP
rs1424098892 1980 dbSNP
rs1215387449 1984 dbSNP
rs1339098299 1984 dbSNP
rs560871668 1985 dbSNP
rs998980292 1988 dbSNP
rs1357452555 1992 dbSNP
rs892876700 1999 dbSNP
rs527845263 2000 dbSNP
rs1268148478 2006 dbSNP
rs11483 2007 dbSNP
rs1308778632 2010 dbSNP
rs776856841 2013 dbSNP
rs1452084040 2020 dbSNP
rs1372929020 2025 dbSNP
rs1440696266 2031 dbSNP
rs1474919794 2034 dbSNP
rs184687661 2034 dbSNP
rs777031942 2034 dbSNP
rs1380374122 2043 dbSNP
rs954715625 2045 dbSNP
rs1391618199 2048 dbSNP
rs1422282100 2055 dbSNP
rs1162340560 2061 dbSNP
rs1020084220 2070 dbSNP
rs568018972 2075 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000401073.2 | 3UTR | UCAAGUCUUCUCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000401073.2 | 3UTR | UCAAGUCUUCUCUAGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
113 hsa-miR-3123 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT058369 TBCEL tubulin folding cofactor E like 2 4
MIRT059816 EFNA1 ephrin A1 2 2
MIRT066850 TMEM19 transmembrane protein 19 2 2
MIRT071503 CALM1 calmodulin 1 2 6
MIRT073758 NUBP1 nucleotide binding protein 1 2 2
MIRT074324 TNRC6A trinucleotide repeat containing 6A 2 10
MIRT094805 LMNB1 lamin B1 2 2
MIRT099173 MAP3K4 mitogen-activated protein kinase kinase kinase 4 2 2
MIRT099545 ID4 inhibitor of DNA binding 4, HLH protein 2 2
MIRT122643 E2F3 E2F transcription factor 3 2 2
MIRT180918 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 8
MIRT192844 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT224984 BAG4 BCL2 associated athanogene 4 2 2
MIRT246065 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT357085 PRRC1 proline rich coiled-coil 1 2 2
MIRT378170 C5ORF51 chromosome 5 open reading frame 51 2 2
MIRT441636 KDM5A lysine demethylase 5A 2 2
MIRT441802 BCAS1 breast carcinoma amplified sequence 1 2 2
MIRT443019 C21orf91 chromosome 21 open reading frame 91 2 2
MIRT443445 SERPINB4 serpin family B member 4 2 2
MIRT443661 SERPINB3 serpin family B member 3 2 2
MIRT443776 STS steroid sulfatase 2 2
MIRT444663 TSPAN14 tetraspanin 14 2 2
MIRT444924 KIAA1522 KIAA1522 2 2
MIRT445378 FOXO1 forkhead box O1 2 2
MIRT447920 PAIP2B poly(A) binding protein interacting protein 2B 2 2
MIRT449202 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT449713 TSPYL1 TSPY like 1 2 2
MIRT450403 TMEM47 transmembrane protein 47 2 2
MIRT450787 PAPOLG poly(A) polymerase gamma 2 2
MIRT451381 C19orf43 telomerase RNA component interacting RNase 2 2
MIRT452507 WDR1 WD repeat domain 1 2 2
MIRT453264 PARP11 poly(ADP-ribose) polymerase family member 11 2 2
MIRT454642 FAM83H family with sequence similarity 83 member H 2 2
MIRT455513 C6orf106 chromosome 6 open reading frame 106 2 2
MIRT456709 LDB1 LIM domain binding 1 2 2
MIRT457231 AP3D1 adaptor related protein complex 3 delta 1 subunit 2 2
MIRT459235 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT460553 IFNAR1 interferon alpha and beta receptor subunit 1 2 4
MIRT461424 CTSL2 cathepsin V 2 3
MIRT462869 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT467178 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT469233 RHOBTB3 Rho related BTB domain containing 3 2 2
MIRT474125 LIPC lipase C, hepatic type 2 2
MIRT475509 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT478134 DHX36 DEAH-box helicase 36 2 2
MIRT481326 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2 2
MIRT482003 AMOTL2 angiomotin like 2 2 2
MIRT482230 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT483436 RHOXF2B Rhox homeobox family member 2B 2 2
MIRT483824 ZC3H12B zinc finger CCCH-type containing 12B 2 2
MIRT492051 TNFSF9 TNF superfamily member 9 2 2
MIRT494114 DLX6 distal-less homeobox 6 2 2
MIRT498882 ZNF12 zinc finger protein 12 2 10
MIRT499674 NPHP3 nephrocystin 3 2 2
MIRT506932 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT509461 ZNF587 zinc finger protein 587 2 6
MIRT510048 AKR1B10 aldo-keto reductase family 1 member B10 2 4
MIRT514807 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT515217 CRCP CGRP receptor component 2 2
MIRT515486 INCENP inner centromere protein 2 4
MIRT517765 ZNF366 zinc finger protein 366 2 4
MIRT518216 TRMT10B tRNA methyltransferase 10B 2 2
MIRT519602 ZNF805 zinc finger protein 805 2 2
MIRT523570 GGCX gamma-glutamyl carboxylase 2 4
MIRT525795 SOD2 superoxide dismutase 2 2 2
MIRT533055 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT534218 SLC37A3 solute carrier family 37 member 3 2 4
MIRT535633 NR2E1 nuclear receptor subfamily 2 group E member 1 2 2
MIRT535863 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT536344 LEFTY1 left-right determination factor 1 2 2
MIRT537923 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT543114 SKA2 spindle and kinetochore associated complex subunit 2 2 2
MIRT544717 ZNF529 zinc finger protein 529 2 2
MIRT544847 BASP1 brain abundant membrane attached signal protein 1 2 4
MIRT545536 ARF3 ADP ribosylation factor 3 2 2
MIRT547124 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT548070 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT548446 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT548626 DAZAP1 DAZ associated protein 1 2 4
MIRT550259 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT551940 AKAP8 A-kinase anchoring protein 8 2 4
MIRT552511 ZIK1 zinc finger protein interacting with K protein 1 2 4
MIRT554015 SPIRE1 spire type actin nucleation factor 1 2 2
MIRT556647 KPNA2 karyopherin subunit alpha 2 2 4
MIRT559744 ACOX1 acyl-CoA oxidase 1 2 2
MIRT560393 TMEM254 transmembrane protein 254 2 2
MIRT562234 HMGB2 high mobility group box 2 2 2
MIRT563325 ORC4 origin recognition complex subunit 4 2 2
MIRT563697 RPS26 ribosomal protein S26 2 2
MIRT565066 USP25 ubiquitin specific peptidase 25 2 2
MIRT565349 TMED2 transmembrane p24 trafficking protein 2 2 2
MIRT565624 SLC31A1 solute carrier family 31 member 1 2 2
MIRT566379 PNISR PNN interacting serine and arginine rich protein 2 2
MIRT567575 FEM1C fem-1 homolog C 2 2
MIRT569383 DDX20 DEAD-box helicase 20 2 2
MIRT570037 FAM228A family with sequence similarity 228 member A 2 2
MIRT573269 DCAF10 DDB1 and CUL4 associated factor 10 2 2
MIRT573912 PARP1 poly(ADP-ribose) polymerase 1 2 2
MIRT620034 ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2 2
MIRT635606 ZWILCH zwilch kinetochore protein 2 2
MIRT644413 FRMD6 FERM domain containing 6 2 2
MIRT652528 TM9SF4 transmembrane 9 superfamily member 4 2 2
MIRT656238 MFSD6 major facilitator superfamily domain containing 6 2 2
MIRT661373 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT662530 PNPLA4 patatin like phospholipase domain containing 4 2 2
MIRT675551 MALL mal, T-cell differentiation protein like 2 2
MIRT693650 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT696348 SLC35D2 solute carrier family 35 member D2 2 2
MIRT705815 AKNA AT-hook transcription factor 2 2
MIRT707632 TARDBP TAR DNA binding protein 2 2
MIRT717902 COPS8 COP9 signalosome subunit 8 2 2
MIRT723626 SOBP sine oculis binding protein homolog 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3123 Doxorubicin 31703 NSC123127 approved sensitive High Triple-Negative Breast Cancer cell line (MDA-MB-231, MDA-MB-468)
hsa-mir-3123 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-3123 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-3123 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3123 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)

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