miRTarBase - #MIRT445345


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pre-miRNA Information
pre-miRNA hsa-mir-488   
Genomic Coordinates chr1: 177029363 - 177029445
Synonyms MIRN488, hsa-mir-488, MIR488
Description Homo sapiens miR-488 stem-loop
Comment miR-488-3p cloned in has a 1 nt 3' extension (U), which is incompatible with the genome sequence.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-488-3p
Sequence 52| UUGAAAGGCUAUUUCUUGGUC |72
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 1 - 177029390 27229138, 28550310, 29165639, 29233923 MiREDiBase
A-to-I 6 1 - 177029389 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN1079766 12 COSMIC
COSN19660590 16 COSMIC
COSN30190142 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1210074726 7 dbSNP
rs1310911055 17 dbSNP
rs1248997320 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol FAM169A   
Synonyms SLAP75
Description family with sequence similarity 169 member A
Transcript NM_015566   
Expression
Putative miRNA Targets on FAM169A
3'UTR of FAM169A
(miRNA target sites are highlighted)		 
>FAM169A|NM_015566|3'UTR
   1 AGGAAGAAGAAAGTGGATGATAAATCCTCTTCTTTGTAACATAGTTGTTGTTTTTAAAATATGGTAATTAATAAACAGCA
  81 TGGGGCACAGGACAAAAATTTCCAAAATTTCAATTTGAACTTACTTACTATGCAGTTTTTTGCTTCCCTTTAGAACGTAG
 161 AATTCACCATTGTTTTTAATTTTCCAGGCTATTTTTGGTAAATGCAATTTTTTATTTTTATTAACCATGTTTCAATTTTG
 241 GGAAACCAGATCATATTATATTTTCTTTATCAGGTGGTACATCTGACCATTATTTCAAAAATATAATTAAAAAGCTGTGA
 321 AAGTAGTAGGATTTCCATTACTTATAAGGATCACAGAAATCTTTTATACTAAGGGTTTTAATAGTAAAACTTGGTGAGGG
 401 TTCTAGAAGTTTTAAATTTCAAAACTAATCACCAATTTTTTAAAATGTAGGCATGCCTAAACAAAAATAAGTGTCAATAA
 481 ATTAGAAAAAATATAACTTCAAGTAAATGAGAGCACAAAAACAGAAACTTACGGTCAAAGGTTCATGAAGATATTTTGGT
 561 TTTGGCCTCTTAATCCTAGATATAGATGCAGTTTTTTCCTTTGACTTCACTATCTATGGAAAGGTACACATAAAATCTGT
 641 TTCTGATTCATTCTATCATCTGATGTTAACAGTACTGTCAGGGATTTAACTGTGGCATGTGGGGACTAATTATTTAAAAT
 721 TTCATTTGAAGTATTAGTTTGCTGTAATTTTTTTTGTCTGCATATGTGCAGACGCCTAGAAGTTTAGACTTTCACCTTTA
 801 ATCAGGTAAAAATCACAACTATACTTTGGAGACATGGTTTAATTTGGACTTCTGGTCCTGATCAGATAGATAAATTAAGC
 881 TGGAGATTTTACTTTTATCCCAACCCAGTTAACATCTATATTTCAGAAGTATGAGGCTCCTTCCTAAGGCATCTCCTTAA
 961 ATCTTGCCACCTCCCTAATTCTACAGTCTTATTTATATTCCCCCACAGCTTTCATCTACTTCTGTAACTCATGGAGTGAT
1041 TCTCCAATCAACAGATCTTCCTGCCTGCCGGCTTATGCCCTTGATGTCCATTTTTGGGTAGGTTTGGAGGTGCACCCCAC
1121 AATGTTAGACCTATATGGCAGGAGTAAAACTGCCCCCAGTGTTAGACCTATATGGCAGGGGTAAACTGCCTTTGGGGGAG
1201 CTGTGGTTACAAGGGCTTCAATCATATTGGAGGCTTCAATCATCCTTTGATTTGTACTGAGTACTGGTTGCAAGCTGGCC
1281 TGTTAAGTATATATTGTGTTGCCATAACAAAGGCCTAGGAAAATTTGAAGAAAAAAAACACTGAACTGTTATTTTTTGTA
1361 ATTTATTTAAAAATGGACAAAATGGTTATTAGAATCCAAAGATAATCTAAAAACAGTTCTACTCTTTGGAAATATTATGT
1441 GTACTCAAATTTGCACTTAAGTTGGAGAATGTTTTGAGACCATTTAAATTGTTTTAAAAATAGCTTGATCTTGATCCTTA
1521 TGCAAAAGAAACTAAGACTTTGTGTCATTATTTGAGGTAGCTAAGGACTGATGTTGAAAGTGTATTCAGTCTATAGTAAG
1601 CTGATGTCAGGTCAGTAAATTTTGTTTGGGGATGTTGGTATTTTCGATCAAGTTAAAATCTTAAAGCAGACAAAAATAGT
1681 AAACGCTCCTATTTGTGTTAGATTTTGAACAATTGTATTACCCTATATTTTCTTTAATTAGTCAAAGGTAAGCCAGATTA
1761 TTTCATTCTAAATGAAAATTAAAGCACTTTGGCCATTTATTTTTTCAACAAATGCTAATACTAAGTAAAAAAAAAAAAGT
1841 ATGACTACTATTAGTGAATCTACCAAACATTTATGCTGTTTTATACATTTTATGAGAAACTTCTGTCAATATCACAAAGG
1921 GAAATACTCTGTTAAGATTCAGTAAATTCTTAATCTTTACATGTTTCATTTCTTAGATTTGAAAACACTTGTAGATATTT
2001 TATTTTTACTTGGATTTGTTTAAAATACTTTCTTTTCAAATTATTTTAAACATGGAAACGCTTCATGAATTTGTGTCATC
2081 CTTGCACAGGGGCCATGCTAATTTTCCCTGTATTGTTCTAATTTTAGTATATGTGCTGCCGAAGTGAGCACTAAAAGACT
2161 TTCTTTAGACAAGTGTAGTTTTTTAAAGATTGAGCTCACTGGCTCAACTCTTGATGTGTGAATATAGTTGAGTTTACAAA
2241 AAATGTTTATTAATCATATATGACCATTGGGGGCTAACAGTATAAACTTATTCTTGTTAAACTTGTTTGGGTTAAATAGT
2321 AAGTGAATTGTAAACAATTTAGAAGTTTTTTGTTCAGCACACAAGAACACTTCTGTTACAGATTCTCTCTGACAGAAATT
2401 GTTATTTTGGGGTTTATAGATTATAGAGGGAAAAGTTAGATCACTTGGAAAAACCTAACTCTCATGTTCAGTAACTTGAG
2481 TATAGAATTTATACCACAATTTATCTTCAATAAGGAACCTACATGAACTTAATCAGTTATCTGTAGTTTTTGCAAGGCAT
2561 TAGAAAAAATTTCACAATTACAGAGGACTGAAAATGTGATTTCAACCGGCTAGTCTAGTTGTTGAATGTCCAGTCACATT
2641 ACACATAGTCCTTTGTGAACTTATTTGTGAAGGGAGTTCACTTTTTATGTACATACGTGTATATTTCCTTGTGTAATATA
2721 AAGCAGATGGTTATTAGTATTTTAGTTCTTTCAAGTTTAAATTATTCAATTGCTAGACATCACAGAAATTAGTATATTTA
2801 AGAATTTATTATAAAGCTCCTCTACAACTTTTAAAGGTGAGAGGGTCTATTATGATTTTTTTATAAAATCAAACAGCATG
2881 ATTTAGAACGTCAGTCTTCTACTTAAAATGTGTCTATATTCATGGTATTTCCATTCAGTGTAGATGGTAAGGAAAACATC
2961 TAGTCATTAAAGATTTACTTATAGCAGACTCCAGAACACTACCTACAATGGGGTTTCAGTGACTAGAAATCTTGAAGGTT
3041 TATGATTGCATCAAATTGAGCCTGTACTAATATCTAAATATCTGCTCTTATGTTCTGCTTTATCCCTTGGGATTACCTTC
3121 TAAGGTTTGGTCACACCAGCAAACTGAAACAGATCTTAATGTACATAAAAAATTTATACTAATATTACTCATCTGTGTTA
3201 CAGTATTTTGAAAAATGTTTCAGGTGTCATCTAGTCGTCTTTCATGGGTGTGATTAGTTACAAATGTTATGCTTATGTTT
3281 TCATACTTAATATCAAGCTTTCTTTGTACCTTACAAGATAGTATTTTTGGTTCTAAAAAAAACAAGCAAACTTCATTTTT
3361 GTAGTATCCAGAAATTACCTGGAGTCAGTATTTTTATTCGCCTTCTAGAACTTGTGATCCACACATCACCCATTTATATT
3441 AGTGGTAAAATTATCTGCTAAAATCTAATTGTAAGAAAGGCTTACCTTCTGTCATCAAGTGATTGTATCATCCTGGATCG
3521 TCATTTCCAAGGAACTAGCCTTTCTTTTCCTAAGCGTCTGTATGTGTTCTAAAACTTCCAGTATATATTTATAGAACTTA
3601 GAAAAAATGTTACATTATTCAGAGTAGCAAGTCTTACTGGAGTACCTATGTTTGTTTTCTTGGTTTTTATTTTTTTTTAA
3681 GTTTAAAAGTAGTAATTAAACCTATATTTTGTGATTGTTTCCTGGTCTGTGTTTTTAAATTCCTTTCCTTCAGTTTTCCT
3761 CATGAAGATGTTTCAGATACTGAATTTGTTTAGACATTGAATGACTTTGTTAAAGGCACAATTAATCACATTGGTTGTAC
3841 TCTGAAGACAGACTTCTTTAAAAAAAAAATAAACAATTTAAAACAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuGGUUCUUU-AUCGGAAAGuu 5'
            |||||:|| |||||||||  
Target 5' ttCCAAGGAACTAGCCTTTCtt 3'
 3525 - 3546 163.00 -21.50
2 
miRNA  3' cuGGUUCUUU--AUCGGAAAGUu 5'
            || ||||:  ||| |||||| 
Target 5' cgCCTAGAAGTTTAGACTTTCAc 3'
 773 - 795 141.00 -12.20
3 
miRNA  3' cuGGUUCUUUAUCGGAAAGUu 5'
            :||   |:| |:|||||| 
Target 5' tgTCATCTAGTCGTCTTTCAt 3'
 3225 - 3245 139.00 -10.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30521176 6 COSMIC
COSN22227455 46 COSMIC
COSN30151219 61 COSMIC
COSN31558519 96 COSMIC
COSN31558956 97 COSMIC
COSN24871633 442 COSMIC
COSN21267535 916 COSMIC
COSN20091208 1064 COSMIC
COSN21937186 1070 COSMIC
COSN32057717 1075 COSMIC
COSN22010340 1538 COSMIC
COSN15750012 1594 COSMIC
COSN29051263 1826 COSMIC
COSN27522028 1827 COSMIC
COSN24551226 2108 COSMIC
COSN1319020 2403 COSMIC
COSN15683282 2417 COSMIC
COSN32058172 2442 COSMIC
COSN22864742 2564 COSMIC
COSN22885482 2668 COSMIC
COSN137334 2804 COSMIC
COSN20101368 2856 COSMIC
COSN31962420 3061 COSMIC
COSN39339 3159 COSMIC
COSN8229068 3859 COSMIC
COSN20101364 3860 COSMIC
COSN20091207 3884 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1358810365 1 dbSNP
rs772962791 2 dbSNP
rs772139541 6 dbSNP
rs1455783329 7 dbSNP
rs373494393 16 dbSNP
rs774270869 18 dbSNP
rs768617020 20 dbSNP
rs1012867069 21 dbSNP
rs757208180 22 dbSNP
rs1398576140 23 dbSNP
rs1392440078 28 dbSNP
rs746054700 30 dbSNP
rs893038953 35 dbSNP
rs781504252 36 dbSNP
rs1383888704 38 dbSNP
rs1191026014 41 dbSNP
rs189973366 43 dbSNP
rs1384532165 48 dbSNP
rs747128003 49 dbSNP
rs761280706 53 dbSNP
rs1305989508 54 dbSNP
rs1333815642 57 dbSNP
rs1032887544 65 dbSNP
rs887566264 69 dbSNP
rs1261272335 73 dbSNP
rs757928736 76 dbSNP
rs1322839846 88 dbSNP
rs558675325 89 dbSNP
rs1380320916 93 dbSNP
rs555077937 105 dbSNP
rs1195491711 108 dbSNP
rs1408292593 113 dbSNP
rs566478941 122 dbSNP
rs546239796 124 dbSNP
rs1183078541 127 dbSNP
rs139333387 130 dbSNP
rs199744243 131 dbSNP
rs917810987 131 dbSNP
rs1056360942 139 dbSNP
rs1479778392 148 dbSNP
rs1173631896 151 dbSNP
rs113748692 153 dbSNP
rs754231250 156 dbSNP
rs923740474 157 dbSNP
rs1191229052 158 dbSNP
rs979234589 158 dbSNP
rs968102060 159 dbSNP
rs1428314944 163 dbSNP
rs1262817057 172 dbSNP
rs1221652153 178 dbSNP
rs1285246773 204 dbSNP
rs920851753 207 dbSNP
rs1298893576 223 dbSNP
rs972311739 226 dbSNP
rs1289032106 227 dbSNP
rs1249835464 235 dbSNP
rs940713920 236 dbSNP
rs1196736189 250 dbSNP
rs1268711778 255 dbSNP
rs1359455954 259 dbSNP
rs1293512445 260 dbSNP
rs1489994685 264 dbSNP
rs1430731353 269 dbSNP
rs77805099 269 dbSNP
rs1433298652 271 dbSNP
rs1169228460 278 dbSNP
rs1370998827 282 dbSNP
rs1463261934 287 dbSNP
rs1298501399 300 dbSNP
rs911340712 304 dbSNP
rs1364785500 310 dbSNP
rs1402970391 311 dbSNP
rs1304910355 321 dbSNP
rs1224734355 331 dbSNP
rs1346151587 344 dbSNP
rs1306740915 346 dbSNP
rs1293601264 351 dbSNP
rs148741124 353 dbSNP
rs1228484583 356 dbSNP
rs982188412 366 dbSNP
rs1146144 367 dbSNP
rs1383907700 370 dbSNP
rs568631741 376 dbSNP
rs1343556971 377 dbSNP
rs1030091031 381 dbSNP
rs994397867 384 dbSNP
rs961626789 406 dbSNP
rs1017112254 412 dbSNP
rs1022835062 417 dbSNP
rs991732257 419 dbSNP
rs1259104678 431 dbSNP
rs1405642993 433 dbSNP
rs1429903399 434 dbSNP
rs1168860877 435 dbSNP
rs1384334033 436 dbSNP
rs1422516629 440 dbSNP
rs1005759799 441 dbSNP
rs1350380432 442 dbSNP
rs887515572 443 dbSNP
rs1166400851 446 dbSNP
rs1364235657 448 dbSNP
rs1044845525 451 dbSNP
rs1382945198 458 dbSNP
rs998751015 459 dbSNP
rs1380954944 471 dbSNP
rs1248642516 472 dbSNP
rs1374043639 474 dbSNP
rs548795497 483 dbSNP
rs1293032053 492 dbSNP
rs531799690 495 dbSNP
rs902876200 502 dbSNP
rs1018609953 503 dbSNP
rs1008686402 504 dbSNP
rs888862051 508 dbSNP
rs117520686 509 dbSNP
rs756454355 511 dbSNP
rs111774226 512 dbSNP
rs899307259 513 dbSNP
rs1036596890 517 dbSNP
rs1156867543 532 dbSNP
rs1400021264 532 dbSNP
rs545891563 533 dbSNP
rs1056539907 535 dbSNP
rs569357560 538 dbSNP
rs935208388 541 dbSNP
rs1357447342 549 dbSNP
rs1457842099 551 dbSNP
rs1336258020 567 dbSNP
rs1454817686 569 dbSNP
rs923896412 575 dbSNP
rs750974381 583 dbSNP
rs946581299 589 dbSNP
rs1222524455 592 dbSNP
rs1193762531 598 dbSNP
rs1309787370 600 dbSNP
rs1318136659 602 dbSNP
rs1208791441 611 dbSNP
rs911288340 612 dbSNP
rs985537997 615 dbSNP
rs955653361 624 dbSNP
rs1459677894 631 dbSNP
rs1205235104 637 dbSNP
rs1046377126 645 dbSNP
rs948038889 645 dbSNP
rs916657925 655 dbSNP
rs922589948 658 dbSNP
rs1321078820 661 dbSNP
rs1282585866 675 dbSNP
rs1223998561 677 dbSNP
rs1175794842 678 dbSNP
rs767983550 682 dbSNP
rs1471049399 698 dbSNP
rs989552765 701 dbSNP
rs1391098817 703 dbSNP
rs1300325158 704 dbSNP
rs560342775 712 dbSNP
rs1223488035 718 dbSNP
rs957452898 719 dbSNP
rs532427191 722 dbSNP
rs1300047164 731 dbSNP
rs973185121 738 dbSNP
rs961613845 740 dbSNP
rs1017229494 741 dbSNP
rs1278898214 742 dbSNP
rs1436957908 756 dbSNP
rs977366878 756 dbSNP
rs967279802 757 dbSNP
rs1483328551 758 dbSNP
rs778984140 761 dbSNP
rs761916633 762 dbSNP
rs1008571776 765 dbSNP
rs970192850 767 dbSNP
rs1481461774 773 dbSNP
rs1023569260 774 dbSNP
rs1419052870 776 dbSNP
rs1408495390 778 dbSNP
rs1172944639 786 dbSNP
rs1371615335 795 dbSNP
rs1404831246 800 dbSNP
rs953044232 805 dbSNP
rs1343024140 808 dbSNP
rs1438005767 809 dbSNP
rs1029176616 816 dbSNP
rs774250771 818 dbSNP
rs1378915033 821 dbSNP
rs1011963499 822 dbSNP
rs1276449126 824 dbSNP
rs1342647046 827 dbSNP
rs1221566083 843 dbSNP
rs1490835545 844 dbSNP
rs1199664977 845 dbSNP
rs994577606 850 dbSNP
rs1474538770 870 dbSNP
rs560127477 872 dbSNP
rs1417930749 874 dbSNP
rs1391131326 880 dbSNP
rs896224748 883 dbSNP
rs899358215 887 dbSNP
rs1034687332 890 dbSNP
rs999181427 891 dbSNP
rs1406530231 893 dbSNP
rs1250813782 899 dbSNP
rs78287124 905 dbSNP
rs1428165425 908 dbSNP
rs1459836767 914 dbSNP
rs1365584349 917 dbSNP
rs865985715 918 dbSNP
rs1244953642 924 dbSNP
rs574704655 929 dbSNP
rs946653272 933 dbSNP
rs1210406678 937 dbSNP
rs377643945 940 dbSNP
rs1277924232 963 dbSNP
rs1190689097 970 dbSNP
rs1238427813 973 dbSNP
rs1444302422 978 dbSNP
rs1387519549 981 dbSNP
rs1336369121 983 dbSNP
rs1473400445 985 dbSNP
rs906795546 986 dbSNP
rs544435461 988 dbSNP
rs1398465233 991 dbSNP
rs575505843 992 dbSNP
rs1322039479 995 dbSNP
rs1388908546 997 dbSNP
rs184702482 998 dbSNP
rs916563675 1002 dbSNP
rs1054305969 1005 dbSNP
rs538749210 1006 dbSNP
rs1245380332 1017 dbSNP
rs572941704 1022 dbSNP
rs562151919 1028 dbSNP
rs972747811 1036 dbSNP
rs1348562330 1043 dbSNP
rs1158435072 1045 dbSNP
rs940029234 1047 dbSNP
rs544076090 1049 dbSNP
rs909904690 1052 dbSNP
rs117191312 1054 dbSNP
rs1180166823 1062 dbSNP
rs763019904 1062 dbSNP
rs1258652524 1064 dbSNP
rs967165351 1069 dbSNP
rs775776946 1070 dbSNP
rs3733794 1075 dbSNP
rs1443862535 1081 dbSNP
rs1471478104 1083 dbSNP
rs1023092014 1089 dbSNP
rs568772976 1091 dbSNP
rs1204433717 1097 dbSNP
rs571714889 1101 dbSNP
rs1468918885 1104 dbSNP
rs1334323612 1106 dbSNP
rs987361981 1111 dbSNP
rs1328006858 1113 dbSNP
rs993441909 1119 dbSNP
rs1333903271 1122 dbSNP
rs745637980 1131 dbSNP
rs776739363 1141 dbSNP
rs1230195590 1142 dbSNP
rs1289044386 1149 dbSNP
rs548593762 1155 dbSNP
rs953184895 1158 dbSNP
rs1288217459 1159 dbSNP
rs1221841083 1162 dbSNP
rs1035210698 1165 dbSNP
rs1257995652 1168 dbSNP
rs999128188 1170 dbSNP
rs1028644463 1179 dbSNP
rs1484308418 1180 dbSNP
rs1183562270 1190 dbSNP
rs1251862187 1191 dbSNP
rs191610460 1194 dbSNP
rs1173453412 1195 dbSNP
rs569116403 1196 dbSNP
rs1378996839 1204 dbSNP
rs995028882 1210 dbSNP
rs552316765 1216 dbSNP
rs963154921 1221 dbSNP
rs1167075695 1223 dbSNP
rs1450646215 1227 dbSNP
rs369974976 1228 dbSNP
rs749000819 1233 dbSNP
rs1303581648 1244 dbSNP
rs1403166300 1244 dbSNP
rs555278248 1254 dbSNP
rs532489905 1259 dbSNP
rs1401762187 1267 dbSNP
rs906680599 1287 dbSNP
rs1010739799 1290 dbSNP
rs1249922441 1291 dbSNP
rs1012483629 1296 dbSNP
rs1344793076 1296 dbSNP
rs1159919051 1300 dbSNP
rs1268818871 1302 dbSNP
rs1490020389 1304 dbSNP
rs1422437875 1305 dbSNP
rs1384227786 1314 dbSNP
rs1268894158 1318 dbSNP
rs1163763226 1324 dbSNP
rs895168859 1325 dbSNP
rs1473670805 1328 dbSNP
rs1240107181 1330 dbSNP
rs1192054441 1331 dbSNP
rs1388048525 1331 dbSNP
rs1431411551 1333 dbSNP
rs1169045908 1336 dbSNP
rs879762262 1337 dbSNP
rs1053786206 1339 dbSNP
rs1422711834 1339 dbSNP
rs1049574340 1341 dbSNP
rs1295335911 1348 dbSNP
rs141717456 1358 dbSNP
rs551969560 1358 dbSNP
rs901242223 1362 dbSNP
rs879198328 1365 dbSNP
rs1220354721 1376 dbSNP
rs138704997 1380 dbSNP
rs1358742069 1385 dbSNP
rs530031745 1388 dbSNP
rs1224492818 1391 dbSNP
rs1292805486 1391 dbSNP
rs1266646289 1393 dbSNP
rs1230199863 1399 dbSNP
rs1488540251 1410 dbSNP
rs1204123476 1416 dbSNP
rs1042463103 1421 dbSNP
rs1051864 1422 dbSNP
rs1188931224 1424 dbSNP
rs199790354 1424 dbSNP
rs373630034 1424 dbSNP
rs1384429364 1427 dbSNP
rs777570421 1432 dbSNP
rs561282121 1438 dbSNP
rs1350472755 1444 dbSNP
rs188306499 1448 dbSNP
rs1391107781 1451 dbSNP
rs1436147754 1456 dbSNP
rs1314770299 1476 dbSNP
rs575569656 1479 dbSNP
rs1301767136 1491 dbSNP
rs1230489167 1492 dbSNP
rs921630036 1496 dbSNP
rs948993884 1513 dbSNP
rs962979236 1520 dbSNP
rs1265739445 1521 dbSNP
rs1465958476 1542 dbSNP
rs1208985588 1553 dbSNP
rs1402573880 1560 dbSNP
rs1364353057 1561 dbSNP
rs1165083041 1563 dbSNP
rs1014638015 1582 dbSNP
rs1183469909 1609 dbSNP
rs1414433900 1613 dbSNP
rs1418504059 1614 dbSNP
rs1406713923 1627 dbSNP
rs1157001411 1629 dbSNP
rs746530218 1635 dbSNP
rs1336359393 1638 dbSNP
rs983141587 1645 dbSNP
rs1450615953 1646 dbSNP
rs970895711 1649 dbSNP
rs1373203936 1662 dbSNP
rs1227144978 1669 dbSNP
rs916181621 1670 dbSNP
rs1285849037 1673 dbSNP
rs866256457 1676 dbSNP
rs960507760 1677 dbSNP
rs1425704218 1681 dbSNP
rs924821103 1684 dbSNP
rs1490215062 1685 dbSNP
rs1211970343 1686 dbSNP
rs565093346 1688 dbSNP
rs1237883474 1691 dbSNP
rs1480256082 1692 dbSNP
rs1179957950 1696 dbSNP
rs1269658378 1701 dbSNP
rs977781348 1712 dbSNP
rs545196061 1713 dbSNP
rs573002798 1720 dbSNP
rs1021915505 1721 dbSNP
rs1010562892 1725 dbSNP
rs1423318903 1726 dbSNP
rs1272831231 1735 dbSNP
rs1481356952 1736 dbSNP
rs1416416366 1740 dbSNP
rs1177210889 1752 dbSNP
rs1354333421 1753 dbSNP
rs1408496942 1756 dbSNP
rs552780225 1762 dbSNP
rs1310392808 1765 dbSNP
rs1032968350 1769 dbSNP
rs1000881640 1777 dbSNP
rs1215530147 1793 dbSNP
rs902487850 1795 dbSNP
rs1365014128 1802 dbSNP
rs1320379131 1809 dbSNP
rs1279015887 1810 dbSNP
rs977046324 1811 dbSNP
rs1281955227 1815 dbSNP
rs1276708913 1816 dbSNP
rs1223395082 1819 dbSNP
rs1344369829 1821 dbSNP
rs1293584361 1822 dbSNP
rs1438246088 1825 dbSNP
rs1483378264 1825 dbSNP
rs1352402826 1826 dbSNP
rs1327695717 1827 dbSNP
rs944090214 1827 dbSNP
rs890327470 1833 dbSNP
rs1226349220 1839 dbSNP
rs1419169538 1839 dbSNP
rs1474762444 1839 dbSNP
rs1051602649 1840 dbSNP
rs1028684241 1850 dbSNP
rs1322282569 1851 dbSNP
rs998134270 1853 dbSNP
rs1164692 1856 dbSNP
rs1275081772 1858 dbSNP
rs1438124003 1858 dbSNP
rs1364124915 1865 dbSNP
rs866701350 1866 dbSNP
rs1225888104 1870 dbSNP
rs1036875315 1871 dbSNP
rs1342755715 1881 dbSNP
rs973697787 1883 dbSNP
rs1287760147 1884 dbSNP
rs1430142358 1886 dbSNP
rs1453405660 1894 dbSNP
rs941716579 1900 dbSNP
rs543826203 1905 dbSNP
rs1447960806 1907 dbSNP
rs1004258726 1909 dbSNP
rs1391221869 1915 dbSNP
rs6453083 1927 dbSNP
rs114226555 1931 dbSNP
rs918120987 1931 dbSNP
rs369659863 1932 dbSNP
rs1323715959 1933 dbSNP
rs1032610038 1952 dbSNP
rs1459395262 1955 dbSNP
rs1322238582 1958 dbSNP
rs1365696085 1960 dbSNP
rs1243887819 1963 dbSNP
rs1282367492 1967 dbSNP
rs1358455077 1968 dbSNP
rs1228957271 1971 dbSNP
rs1001505663 1979 dbSNP
rs1463696213 1985 dbSNP
rs966728475 1986 dbSNP
rs948756711 1989 dbSNP
rs1461152773 1991 dbSNP
rs916146828 1995 dbSNP
rs1301444845 1996 dbSNP
rs1473452117 1998 dbSNP
rs1220463367 2007 dbSNP
rs1008355829 2017 dbSNP
rs144802215 2018 dbSNP
rs569177699 2031 dbSNP
rs996035646 2032 dbSNP
rs924747177 2042 dbSNP
rs1332021865 2051 dbSNP
rs552380016 2059 dbSNP
rs142619306 2060 dbSNP
rs867290679 2071 dbSNP
rs1327204005 2077 dbSNP
rs1037649449 2078 dbSNP
rs796583757 2090 dbSNP
rs1334432527 2103 dbSNP
rs1344654332 2105 dbSNP
rs1469286755 2107 dbSNP
rs138094632 2117 dbSNP
rs915021035 2120 dbSNP
rs989088451 2127 dbSNP
rs1359678156 2128 dbSNP
rs1443445469 2130 dbSNP
rs941940977 2131 dbSNP
rs1250337845 2134 dbSNP
rs546773719 2141 dbSNP
rs1399050265 2148 dbSNP
rs1047385977 2151 dbSNP
rs1028004792 2153 dbSNP
rs1179544681 2153 dbSNP
rs879731248 2166 dbSNP
rs949017131 2166 dbSNP
rs1441758541 2167 dbSNP
rs1307347836 2171 dbSNP
rs768211827 2173 dbSNP
rs998478212 2174 dbSNP
rs1453396360 2191 dbSNP
rs1183365472 2202 dbSNP
rs965328020 2203 dbSNP
rs990947404 2205 dbSNP
rs1015432408 2214 dbSNP
rs1004081947 2232 dbSNP
rs1346151897 2233 dbSNP
rs888516329 2235 dbSNP
rs1273090216 2236 dbSNP
rs959585821 2237 dbSNP
rs1048531027 2241 dbSNP
rs1013020653 2248 dbSNP
rs925429530 2255 dbSNP
rs1196345915 2256 dbSNP
rs1314653300 2258 dbSNP
rs1435123074 2259 dbSNP
rs1167797667 2262 dbSNP
rs1368629997 2272 dbSNP
rs1282913790 2274 dbSNP
rs1308659689 2279 dbSNP
rs894437248 2280 dbSNP
rs1385234785 2294 dbSNP
rs1303691934 2296 dbSNP
rs1331957473 2310 dbSNP
rs1378648973 2313 dbSNP
rs1312373340 2323 dbSNP
rs1344906494 2325 dbSNP
rs1451665646 2330 dbSNP
rs979714208 2342 dbSNP
rs1057139120 2352 dbSNP
rs966948164 2355 dbSNP
rs1021178569 2364 dbSNP
rs1207641739 2364 dbSNP
rs1008238040 2369 dbSNP
rs530160933 2372 dbSNP
rs561136634 2373 dbSNP
rs1041855624 2374 dbSNP
rs997319312 2381 dbSNP
rs900364031 2382 dbSNP
rs1037932617 2383 dbSNP
rs947580739 2385 dbSNP
rs1295429767 2387 dbSNP
rs1391685204 2391 dbSNP
rs1434705382 2402 dbSNP
rs529260318 2404 dbSNP
rs1367836897 2409 dbSNP
rs1229707055 2411 dbSNP
rs914762614 2423 dbSNP
rs1383626108 2426 dbSNP
rs1047604105 2428 dbSNP
rs1241982783 2430 dbSNP
rs1163112177 2434 dbSNP
rs1424786382 2435 dbSNP
rs1258663347 2442 dbSNP
rs778602626 2452 dbSNP
rs754470064 2454 dbSNP
rs550962017 2456 dbSNP
rs932428339 2457 dbSNP
rs920891094 2458 dbSNP
rs1485818752 2459 dbSNP
rs917551171 2461 dbSNP
rs1245892196 2463 dbSNP
rs1216709847 2464 dbSNP
rs1186944636 2470 dbSNP
rs976482581 2478 dbSNP
rs1355155328 2483 dbSNP
rs1255378114 2492 dbSNP
rs1289172332 2493 dbSNP
rs1422026313 2495 dbSNP
rs1166971460 2502 dbSNP
rs1244741000 2505 dbSNP
rs183649344 2522 dbSNP
rs1322149191 2528 dbSNP
rs1157225070 2533 dbSNP
rs1054909548 2536 dbSNP
rs937750204 2539 dbSNP
rs1302705007 2540 dbSNP
rs965280355 2541 dbSNP
rs1015545562 2542 dbSNP
rs1408951921 2543 dbSNP
rs1334921286 2545 dbSNP
rs982592928 2547 dbSNP
rs1302769804 2558 dbSNP
rs925513436 2561 dbSNP
rs1330850021 2568 dbSNP
rs1216201634 2570 dbSNP
rs1236732799 2573 dbSNP
rs1482206544 2575 dbSNP
rs1361185278 2577 dbSNP
rs1298666576 2580 dbSNP
rs1472314571 2580 dbSNP
rs952500790 2594 dbSNP
rs1180179649 2599 dbSNP
rs979598148 2605 dbSNP
rs1026833020 2607 dbSNP
rs1175773194 2608 dbSNP
rs1013382193 2613 dbSNP
rs1467966972 2616 dbSNP
rs1314032364 2620 dbSNP
rs565155405 2621 dbSNP
rs1036093229 2624 dbSNP
rs192576308 2627 dbSNP
rs528288691 2632 dbSNP
rs559447082 2637 dbSNP
rs1277604565 2638 dbSNP
rs987025224 2643 dbSNP
rs1458581397 2646 dbSNP
rs955423905 2646 dbSNP
rs1212080605 2648 dbSNP
rs1028730045 2649 dbSNP
rs1482727307 2650 dbSNP
rs1370618359 2657 dbSNP
rs975559945 2660 dbSNP
rs1254136619 2663 dbSNP
rs542363993 2664 dbSNP
rs774984740 2674 dbSNP
rs1423424938 2682 dbSNP
rs1435262104 2682 dbSNP
rs1370448766 2687 dbSNP
rs1424987003 2687 dbSNP
rs1428437118 2692 dbSNP
rs1196409613 2693 dbSNP
rs112719944 2696 dbSNP
rs1355804859 2697 dbSNP
rs1442397321 2703 dbSNP
rs1266114212 2708 dbSNP
rs903428215 2709 dbSNP
rs1006017950 2715 dbSNP
rs751128496 2717 dbSNP
rs886244270 2729 dbSNP
rs1208922291 2742 dbSNP
rs1236218949 2743 dbSNP
rs769234817 2746 dbSNP
rs1341347731 2749 dbSNP
rs1202967250 2750 dbSNP
rs1267067121 2753 dbSNP
rs1041929131 2757 dbSNP
rs1224980152 2765 dbSNP
rs1438475135 2765 dbSNP
rs947655720 2769 dbSNP
rs1245195039 2772 dbSNP
rs1489610121 2773 dbSNP
rs750749366 2778 dbSNP
rs1013904015 2779 dbSNP
rs1278795762 2783 dbSNP
rs1171040378 2789 dbSNP
rs893274082 2790 dbSNP
rs1410027050 2791 dbSNP
rs1322382544 2794 dbSNP
rs1347727114 2801 dbSNP
rs1442716851 2804 dbSNP
rs1343769575 2807 dbSNP
rs1326281484 2811 dbSNP
rs896186430 2818 dbSNP
rs1050620359 2819 dbSNP
rs937650325 2822 dbSNP
rs932392095 2828 dbSNP
rs556702373 2833 dbSNP
rs150295381 2835 dbSNP
rs943705980 2839 dbSNP
rs1247724426 2845 dbSNP
rs945545749 2848 dbSNP
rs1190971634 2853 dbSNP
rs1243195817 2861 dbSNP
rs1472782747 2862 dbSNP
rs11327417 2863 dbSNP
rs987078854 2863 dbSNP
rs1462659145 2872 dbSNP
rs1461815923 2874 dbSNP
rs908223105 2878 dbSNP
rs1387522182 2883 dbSNP
rs1401431509 2883 dbSNP
rs1173505166 2884 dbSNP
rs781683131 2889 dbSNP
rs1320089541 2890 dbSNP
rs1479731016 2895 dbSNP
rs1457066361 2902 dbSNP
rs1426671279 2912 dbSNP
rs1197548878 2913 dbSNP
rs1282458989 2916 dbSNP
rs982666751 2916 dbSNP
rs1433198853 2918 dbSNP
rs952615019 2922 dbSNP
rs921315321 2923 dbSNP
rs575564344 2925 dbSNP
rs1457181804 2932 dbSNP
rs1413134535 2938 dbSNP
rs1258440022 2941 dbSNP
rs1027193737 2942 dbSNP
rs1285453811 2944 dbSNP
rs1200510928 2945 dbSNP
rs975822499 2947 dbSNP
rs991373332 2948 dbSNP
rs188664136 2962 dbSNP
rs550220203 2982 dbSNP
rs1410724614 2983 dbSNP
rs183780823 3002 dbSNP
rs1234073337 3007 dbSNP
rs1035803069 3008 dbSNP
rs982807947 3010 dbSNP
rs1002932186 3019 dbSNP
rs1413771188 3021 dbSNP
rs903164964 3022 dbSNP
rs1332855592 3025 dbSNP
rs867039165 3036 dbSNP
rs1026093041 3038 dbSNP
rs1415472404 3042 dbSNP
rs1011746863 3046 dbSNP
rs893430983 3048 dbSNP
rs1051023587 3060 dbSNP
rs1348835881 3062 dbSNP
rs1241478849 3070 dbSNP
rs140141812 3073 dbSNP
rs1344760243 3074 dbSNP
rs1013541385 3077 dbSNP
rs896394016 3091 dbSNP
rs757706876 3110 dbSNP
rs1486305610 3119 dbSNP
rs1210949018 3127 dbSNP
rs1033565857 3140 dbSNP
rs899559668 3142 dbSNP
rs1183541476 3151 dbSNP
rs1040773048 3165 dbSNP
rs943782493 3166 dbSNP
rs1477566766 3168 dbSNP
rs1002290871 3169 dbSNP
rs908174988 3173 dbSNP
rs151163741 3175 dbSNP
rs769244317 3182 dbSNP
rs1307447767 3191 dbSNP
rs1468765492 3196 dbSNP
rs553490524 3199 dbSNP
rs751668599 3200 dbSNP
rs931215228 3201 dbSNP
rs903497003 3202 dbSNP
rs1393295735 3210 dbSNP
rs1307998731 3224 dbSNP
rs1043518791 3236 dbSNP
rs192874425 3237 dbSNP
rs1173617650 3239 dbSNP
rs892673762 3240 dbSNP
rs1349164625 3243 dbSNP
rs1228349433 3244 dbSNP
rs991714332 3245 dbSNP
rs958543030 3250 dbSNP
rs934136798 3252 dbSNP
rs928471774 3270 dbSNP
rs1197095070 3276 dbSNP
rs567722003 3291 dbSNP
rs1378826773 3297 dbSNP
rs981460389 3301 dbSNP
rs1191491928 3306 dbSNP
rs1179276510 3308 dbSNP
rs967440837 3312 dbSNP
rs1020240847 3313 dbSNP
rs1011568740 3318 dbSNP
rs1238631639 3343 dbSNP
rs1463581391 3356 dbSNP
rs957841344 3359 dbSNP
rs543320964 3366 dbSNP
rs982860146 3367 dbSNP
rs1200923070 3368 dbSNP
rs1372185492 3369 dbSNP
rs530912978 3374 dbSNP
rs901979861 3378 dbSNP
rs762697634 3390 dbSNP
rs917291283 3399 dbSNP
rs539365752 3400 dbSNP
rs1354681951 3410 dbSNP
rs960539017 3418 dbSNP
rs1211474773 3422 dbSNP
rs1007940469 3425 dbSNP
rs1034031853 3426 dbSNP
rs752912563 3437 dbSNP
rs1046751460 3438 dbSNP
rs967733798 3441 dbSNP
rs878874778 3455 dbSNP
rs1430284352 3460 dbSNP
rs1171163220 3464 dbSNP
rs1335492263 3476 dbSNP
rs1460008782 3481 dbSNP
rs1167386908 3485 dbSNP
rs1398277386 3498 dbSNP
rs1021959529 3505 dbSNP
rs1434820497 3507 dbSNP
rs551701502 3507 dbSNP
rs1319011913 3510 dbSNP
rs765527881 3512 dbSNP
rs892223481 3520 dbSNP
rs1295630525 3535 dbSNP
rs1156297568 3539 dbSNP
rs1055687545 3540 dbSNP
rs937265949 3555 dbSNP
rs1274652169 3556 dbSNP
rs1335155820 3557 dbSNP
rs928450756 3560 dbSNP
rs1486782078 3569 dbSNP
rs1187040535 3580 dbSNP
rs34117506 3580 dbSNP
rs981283277 3581 dbSNP
rs1255487052 3584 dbSNP
rs188432788 3585 dbSNP
rs967429567 3592 dbSNP
rs1418808964 3600 dbSNP
rs1442576477 3600 dbSNP
rs1456960065 3606 dbSNP
rs1157315500 3609 dbSNP
rs1347350011 3621 dbSNP
rs913346394 3646 dbSNP
rs1236649875 3653 dbSNP
rs990088199 3661 dbSNP
rs1188223806 3666 dbSNP
rs1374238816 3669 dbSNP
rs776804194 3670 dbSNP
rs941605055 3671 dbSNP
rs1259824355 3673 dbSNP
rs909921811 3679 dbSNP
rs1355639073 3682 dbSNP
rs957369481 3695 dbSNP
rs182532509 3698 dbSNP
rs11950502 3701 dbSNP
rs966697054 3704 dbSNP
rs1216305161 3711 dbSNP
rs1255335733 3715 dbSNP
rs917342250 3730 dbSNP
rs1285137994 3741 dbSNP
rs1420500897 3742 dbSNP
rs15694 3743 dbSNP
rs1258345930 3751 dbSNP
rs1325200417 3753 dbSNP
rs960846238 3753 dbSNP
rs1410550586 3762 dbSNP
rs926462904 3775 dbSNP
rs1298061082 3777 dbSNP
rs1005087738 3782 dbSNP
rs1437181224 3783 dbSNP
rs1314132571 3784 dbSNP
rs967956476 3796 dbSNP
rs886839986 3797 dbSNP
rs1422336932 3801 dbSNP
rs1025374699 3802 dbSNP
rs1296073969 3803 dbSNP
rs1375129780 3804 dbSNP
rs1224126599 3808 dbSNP
rs1300403164 3809 dbSNP
rs529005218 3819 dbSNP
rs199948642 3827 dbSNP
rs1236411062 3828 dbSNP
rs995677980 3829 dbSNP
rs1473619961 3831 dbSNP
rs115406146 3838 dbSNP
rs1202578139 3838 dbSNP
rs1481118437 3839 dbSNP
rs1192794742 3845 dbSNP
rs956331317 3846 dbSNP
rs1393667871 3854 dbSNP
rs1455936167 3856 dbSNP
rs1052058 3860 dbSNP
rs1174845738 3861 dbSNP
rs1390159598 3864 dbSNP
rs1408832468 3868 dbSNP
rs1355907773 3870 dbSNP
rs142899821 3870 dbSNP
rs1442503116 3870 dbSNP
rs997929398 3871 dbSNP
rs1368554290 3873 dbSNP
rs1304036697 3874 dbSNP
rs1442946345 3874 dbSNP
rs541526853 3875 dbSNP
rs900030553 3877 dbSNP
rs1055872109 3878 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000380515.3 | 3UTR | UCAAGUUUAAAUUAUUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.666 1.9e-4 -0.560 2.2e-3 24 Click to see details
GSE28260 Renal cortex and medulla 0.706 3.5e-3 0.768 1.1e-3 13 Click to see details
GSE19350 CNS germ cell tumors -0.617 1.6e-2 -0.790 1.1e-3 12 Click to see details
GSE17306 Multiple myeloma 0.243 4.6e-2 0.530 4.5e-5 49 Click to see details
GSE32688 Pancreatic cancer 0.243 9.0e-2 0.298 4.9e-2 32 Click to see details
GSE26953 Aortic valvular endothelial cells 0.281 9.2e-2 0.010 4.8e-1 24 Click to see details
GSE42095 Differentiated embryonic stem cells -0.277 1.0e-1 -0.205 1.7e-1 23 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.25 1.1e-1 -0.181 1.9e-1 25 Click to see details
GSE21687 Ependynoma primary tumors 0.113 1.9e-1 0.234 3.1e-2 64 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.119 3.1e-1 -0.057 4.1e-1 20 Click to see details
GSE38226 Liver fibrosis 0.095 3.4e-1 -0.016 4.7e-1 21 Click to see details
GSE17498 Multiple myeloma 0.036 4.1e-1 0.145 1.9e-1 40 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.109 4.7e-1 -0.500 3.3e-1 3 Click to see details
GSE21849 B cell lymphoma 0.009 4.8e-1 0.282 6.9e-2 29 Click to see details
GSE21849 B cell lymphoma 0.009 4.8e-1 0.282 6.9e-2 29 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LUSC 0.902 0.01 0.771 0.04 6 Click to see details
HNSC 0.602 0.1 0.600 0.1 6 Click to see details
PRAD -0.222 0.2 -0.132 0.31 16 Click to see details
BRCA 0.215 0.24 0.269 0.19 13 Click to see details
LIHC 0.263 0.26 0.333 0.21 8 Click to see details
UCEC 0.19 0.28 0.210 0.26 12 Click to see details
THCA -0.251 0.37 0.200 0.4 4 Click to see details
PCPG -0.229 0.43 -0.500 0.33 3 Click to see details
KIRP 0.098 0.44 0.300 0.31 5 Click to see details
ESCA 0.141 0.45 0.500 0.33 3 Click to see details
ESCA 0.141 0.45 0.500 0.33 3 Click to see details
ESCA 0.141 0.45 0.500 0.33 3 Click to see details
ESCA 0.141 0.45 0.500 0.33 3 Click to see details
ESCA 0.141 0.45 0.500 0.33 3 Click to see details
ESCA 0.141 0.45 0.500 0.33 3 Click to see details
116 hsa-miR-488-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT005899 POMC proopiomelanocortin 3 1
MIRT038008 CYP2E1 cytochrome P450 family 2 subfamily E member 1 1 1
MIRT054483 SLC39A8 solute carrier family 39 member 8 2 1
MIRT058884 C11ORF58 chromosome 11 open reading frame 58 2 2
MIRT061194 MED17 mediator complex subunit 17 2 2
MIRT167237 TMEM167A transmembrane protein 167A 2 2
MIRT188343 ARID1A AT-rich interaction domain 1A 2 2
MIRT218170 MRPL18 mitochondrial ribosomal protein L18 2 2
MIRT218297 C6ORF120 chromosome 6 open reading frame 120 2 2
MIRT263337 ANAPC16 anaphase promoting complex subunit 16 2 2
MIRT294633 ZNF548 zinc finger protein 548 2 2
MIRT305053 SRPRB SRP receptor beta subunit 2 6
MIRT306846 FYTTD1 forty-two-three domain containing 1 2 2
MIRT442753 NRIP3 nuclear receptor interacting protein 3 2 2
MIRT443955 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT444032 SYNM synemin 2 2
MIRT444519 WWTR1 WW domain containing transcription regulator 1 2 2
MIRT444569 UNC5C unc-5 netrin receptor C 2 2
MIRT444779 ECE1 endothelin converting enzyme 1 2 2
MIRT445195 FAXC failed axon connections homolog 2 2
MIRT445345 FAM169A family with sequence similarity 169 member A 2 2
MIRT445539 TBC1D8 TBC1 domain family member 8 2 2
MIRT446058 RABIF RAB interacting factor 2 2
MIRT446358 EFCAB6 EF-hand calcium binding domain 6 2 2
MIRT446486 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT446973 CARKD NAD(P)HX dehydratase 2 2
MIRT446984 MOB1B MOB kinase activator 1B 2 2
MIRT446987 TMEM9B TMEM9 domain family member B 2 2
MIRT447376 AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 2 2
MIRT447857 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT448077 BRMS1L breast cancer metastasis-suppressor 1 like 2 2
MIRT448970 CBX5 chromobox 5 2 2
MIRT449072 RPS15A ribosomal protein S15a 2 2
MIRT449200 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT449459 HAT1 histone acetyltransferase 1 2 2
MIRT449588 PCDHA6 protocadherin alpha 6 2 2
MIRT449885 ZNF621 zinc finger protein 621 2 2
MIRT449892 C11orf34 placenta expressed transcript 1 1 2
MIRT450669 SGIP1 SH3 domain GRB2 like endophilin interacting protein 1 2 2
MIRT450866 GPR107 G protein-coupled receptor 107 2 2
MIRT450881 EIF6 eukaryotic translation initiation factor 6 2 2
MIRT455373 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT458266 FUT10 fucosyltransferase 10 2 2
MIRT464839 RPS27A ribosomal protein S27a 2 12
MIRT465335 TPM3 tropomyosin 3 2 4
MIRT467939 SLC16A1 solute carrier family 16 member 1 2 2
MIRT468719 SDC4 syndecan 4 2 2
MIRT469844 PXK PX domain containing serine/threonine kinase like 2 8
MIRT474545 KLHDC3 kelch domain containing 3 2 2
MIRT480700 BRPF1 bromodomain and PHD finger containing 1 2 2
MIRT482087 ALG8 ALG8, alpha-1,3-glucosyltransferase 2 2
MIRT491225 KCNA5 potassium voltage-gated channel subfamily A member 5 2 2
MIRT497790 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT497831 GPR26 G protein-coupled receptor 26 2 2
MIRT497910 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 2 2
MIRT498428 DDX39A DExD-box helicase 39A 2 2
MIRT499196 TJAP1 tight junction associated protein 1 2 2
MIRT500396 ZNF281 zinc finger protein 281 2 6
MIRT501523 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 10
MIRT504445 MC2R melanocortin 2 receptor 2 2
MIRT505270 TUBB2A tubulin beta 2A class IIa 2 2
MIRT508584 CCDC115 coiled-coil domain containing 115 2 12
MIRT509269 NPM3 nucleophosmin/nucleoplasmin 3 2 4
MIRT512466 CCDC149 coiled-coil domain containing 149 2 2
MIRT513534 PRDM2 PR/SET domain 2 2 4
MIRT514218 ZNF83 zinc finger protein 83 2 4
MIRT518526 FLCN folliculin 2 6
MIRT524841 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT524855 ARL5B ADP ribosylation factor like GTPase 5B 2 4
MIRT525048 FRK fyn related Src family tyrosine kinase 2 2
MIRT528635 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT529557 SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 2 2
MIRT532319 GHSR growth hormone secretagogue receptor 2 2
MIRT534232 SLC25A16 solute carrier family 25 member 16 2 2
MIRT534254 SLC12A7 solute carrier family 12 member 7 2 2
MIRT536223 LRRC41 leucine rich repeat containing 41 2 2
MIRT537658 ERBB2IP erbb2 interacting protein 2 2
MIRT537795 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT540404 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 2
MIRT544563 POLDIP3 DNA polymerase delta interacting protein 3 2 2
MIRT546045 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT546846 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT548480 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT549337 ARF6 ADP ribosylation factor 6 2 2
MIRT550855 SNAP47 synaptosome associated protein 47 2 4
MIRT551607 ZNF267 zinc finger protein 267 2 2
MIRT553222 TWF1 twinfilin actin binding protein 1 2 2
MIRT553874 SUPT7L SPT7 like, STAGA complex gamma subunit 2 4
MIRT557956 FAM222B family with sequence similarity 222 member B 2 2
MIRT559264 BAG4 BCL2 associated athanogene 4 2 4
MIRT562245 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT563184 YDJC YdjC chitooligosaccharide deacetylase homolog 2 2
MIRT563834 SMDT1 single-pass membrane protein with aspartate rich tail 1 2 2
MIRT563967 RAB6A RAB6A, member RAS oncogene family 2 2
MIRT564808 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565188 TSHZ1 teashirt zinc finger homeobox 1 2 2
MIRT565549 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 2
MIRT566969 LBR lamin B receptor 2 2
MIRT570926 ZNF284 zinc finger protein 284 2 2
MIRT612283 ZMAT3 zinc finger matrin-type 3 2 2
MIRT612695 PKNOX1 PBX/knotted 1 homeobox 1 2 2
MIRT625293 ZNF619 zinc finger protein 619 2 2
MIRT628496 LINS lines homolog 1 2 2
MIRT640282 FAM169B family with sequence similarity 169 member B 2 2
MIRT647212 CYP2U1 cytochrome P450 family 2 subfamily U member 1 2 2
MIRT654668 PSMB5 proteasome subunit beta 5 2 2
MIRT657516 HAS2 hyaluronan synthase 2 2 2
MIRT670337 C1orf106 chromosome 1 open reading frame 106 2 4
MIRT702010 MIDN midnolin 2 2
MIRT704253 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT710205 ENAH ENAH, actin regulator 2 2
MIRT712126 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT714890 COQ10B coenzyme Q10B 2 2
MIRT716588 PAX6 paired box 6 2 2
MIRT720810 CIAO1 cytosolic iron-sulfur assembly component 1 2 2
MIRT724953 AHCY adenosylhomocysteinase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-488 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-488 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-488 Doxorubicin 31703 NSC123127 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-488 Chemotherapy sensitive High Epithelial Ovarian Cancer tissue
hsa-miR-488 Cisplatin 5460033 NSC119875 approved resistant Low Non-Small Cell Lung Cancer cell line (A549, H1299)
hsa-miR-488 Daunorubicin 30323 NSC82151 approved resistant High Acute Promyelocytic Leukemia cell line (HL60)
hsa-miR-488 Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375)
hsa-miR-488 Taxane 9548828 sensitive High Breast Cancer tissue
hsa-miR-488 Doxorubicin 31703 NSC123127 approved sensitive High Anaplastic Thyroid Cancer tissue
hsa-mir-488 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-488 Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-miR-488 Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-488 Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-488 Doxorubicin 31703 NSC123127 approved resistant cell line (K562)
hsa-miR-488 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-488-3p Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-488-3p Cisplatin 5460033 NSC119875 approved sensitive Low Melanoma cell line (SK-Mel-28)
hsa-miR-488-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-488-3p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-488-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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