miRTarBase - #MIRT445630


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pre-miRNA Information
pre-miRNA hsa-mir-3915   
Genomic Coordinates chrX: 32583656 - 32583752
Description Homo sapiens miR-3915 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3915
Sequence 21| UUGAGGAAAAGAUGGUCUUAUU |42
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs997323565 10 dbSNP
rs1192161547 15 dbSNP
rs1255075246 19 dbSNP
rs1452812574 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TMEM50A   
Synonyms IFNRC, SMP1
Description transmembrane protein 50A
Transcript NM_014313   
Expression
Putative miRNA Targets on TMEM50A
3'UTR of TMEM50A
(miRNA target sites are highlighted)		 
>TMEM50A|NM_014313|3'UTR
   1 ACACATCTGATTTCCCACAGCACAACAGCCCTGCATGGGTTTGTTTGTTTTTTTACTGCTCACTCCCAACCTTTTGTAAT
  81 GCCATTTTCTAAACTTATTTCTGAGTGTAGTCTCAGCTTAAAGTTGTGTAATACTAAAATCACGAGAACACCTAAACAAC
 161 AACCAAAAATCTATTGTGGTATGCACTTGATTAACTTATAAAATGTTAGAGGAAACTTTCACATGAATAATTTTTGTCAA
 241 ATTTTATCATGGTATAATTTGTAAAAATAAAAAGAAATTACAAAAGAAATTATGGATTTGTCAATGTAAGTATTTGTCAT
 321 ATCTGAGGTCCAAAACCACAATGAAAGTGCTCTGAAGATTTAATGTGTTTATTCAAATGTGGTCTCTTCTGTGTCAAATG
 401 TTAAATGAAATATAAACATTTTTTAGTTTTTAAAATATTCCGTGGTCAAAATTCTTCCTCACTATAATTGGTATTTACTT
 481 TTACCAAAAATTCTGTGAACATGTAATGTAACTGGCTTTTGAGGGTCTCCCAAGGGGTGAGTGGACGTGTTGGAAGAGAG
 561 AAGCACCATGGTCCAGCCACCAGGCTCCCTGTGTCCCTTCCATGGGAAGGTCTTCCGCTGTGCCTCTCATTCCAAGGGCA
 641 GGAAGATGTGACTCAGCCATGACACGTGGTTCTGGTGGGATGCACAGTCACTCCACATCCACCATTGAAGGAAAGGAAAA
 721 AAGGGCAGAGACTTGACACTCCAGTCTTAGACAGGGGACAATTTCTTTGTAGTTGTTCTGATAATAAACTGGGTTCCATG
 801 TTGCATTTCATCTGTGTACTGAACCACTAGCCTAATAGACCAGCACGGTCAACTAGAATGACAAACATTAGCTACTGGGA
 881 ACTCTTGTTGTCTCTTCCTCTTCAGAACTCTTGTCCCCCCAGGCTCCCCACCTCTGCAAGATGGGATACACTCTTCAGGA
 961 CCACAGTTTGAAATGTCTTTCATAAAATGTGCTACAATTAGCCTTCGGAATATTTGCTGGGTGATTTAAATGTGTGGGTC
1041 TCATTTCCATGCTAGCCATGGTCATCTGACAGTCTCTACACTGTGAATATTGCCTGGTGATCAAGACTCTCCTCAAAGAA
1121 ATGACTTGCTGTCATCCCACATGAACTCCTGATGTTTTTTCTACAAAAGTCCATAAAATGTGAAAACTGGAGAAGATCTT
1201 AGAGGTTGAAGCCCACCTTCTCTTTTCACATAGGAGGGAACAGACCATGGAAATTTAAACGACTTCCTCACGGTCACAGA
1281 ACTAGTTTTTTAATCCTCAGGCAGTGCATCCCCCCACCCTACAACTGAGCACAACCTCTTTCCCCACAGTGCAATTCAGA
1361 ATATGCTCAGGGAATGCCAGCCACCTTGTAAAACTGCTGGGAGAAAAGCATGATTCCCACAAGGACTAAGTATCAGTGAT
1441 TTGTAATTTTCCTGTTTTGTATTATCTGCTTTGCTGATGTAGACAAGAGTTAACTGAGTAGCATGCTTTATTAAGCATGA
1521 GAAAGAATCTTAAGAATTGTCAATAAAATTAACCCAAAACTTTAATAATGTGTCTGTAACCAAGAAAATATTGATAGCAT
1601 CATCCTAATGAAACTAAACATTTATTTTAAACTTATTAAATTGACTCTTAAACTAAAAAAAAAAAAAAAAAAAAAAAAAA
1681 A
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuauUCUGGUA-----GAA-------AAGGAGUu 5'
              |||||||     :||       ||||||| 
Target 5' gaacAGACCATGGAAATTTAAACGACTTCCTCAc 3'
 1238 - 1271 150.00 -12.90
2 
miRNA  3' uuauuCUGG--UAGAAAAGGAGUu 5'
               |::|  | :| ||||||| 
Target 5' tccgtGGTCAAAATTCTTCCTCAc 3'
 439 - 462 147.00 -9.30
3 
miRNA  3' uuauucUGGUAGAAAAGGAGuu 5'
                ::::||| ||||||  
Target 5' actcttGTTGTCTCTTCCTCtt 3'
 881 - 902 136.00 -10.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31506301 23 COSMIC
COSN30112593 30 COSMIC
COSN29193741 38 COSMIC
COSN511192 39 COSMIC
COSN31535477 40 COSMIC
COSN26999072 45 COSMIC
COSN30128544 55 COSMIC
COSN30169334 66 COSMIC
COSN30453916 68 COSMIC
COSN30521882 111 COSMIC
COSN31492174 115 COSMIC
COSN30103665 151 COSMIC
COSN31597811 180 COSMIC
COSN31558820 190 COSMIC
COSN20608339 305 COSMIC
COSN22897631 435 COSMIC
COSN6451290 706 COSMIC
COSN31960199 847 COSMIC
COSN6032607 1273 COSMIC
COSN31778009 1343 COSMIC
COSN31513763 1590 COSMIC
COSN30135837 1601 COSMIC
COSN19585561 1609 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1225108321 6 dbSNP
rs779274327 11 dbSNP
rs1427940787 15 dbSNP
rs200789909 26 dbSNP
rs369073229 27 dbSNP
rs1252728981 29 dbSNP
rs747174833 30 dbSNP
rs768759619 32 dbSNP
rs1185375423 33 dbSNP
rs1367776318 39 dbSNP
rs200542812 43 dbSNP
rs749935359 45 dbSNP
rs1063895 48 dbSNP
rs1368376862 48 dbSNP
rs368088624 52 dbSNP
rs1390804301 55 dbSNP
rs1423381135 57 dbSNP
rs1429834593 61 dbSNP
rs1286895450 62 dbSNP
rs371512666 64 dbSNP
rs1234903323 66 dbSNP
rs1302524319 70 dbSNP
rs1345860880 75 dbSNP
rs15309 102 dbSNP
rs111818001 105 dbSNP
rs993265950 106 dbSNP
rs140746704 107 dbSNP
rs185211529 110 dbSNP
rs8876 113 dbSNP
rs3093657 121 dbSNP
rs910498443 127 dbSNP
rs752780151 129 dbSNP
rs557306246 162 dbSNP
rs1193590733 164 dbSNP
rs759341121 165 dbSNP
rs1007511421 167 dbSNP
rs1017813583 174 dbSNP
rs1452044632 180 dbSNP
rs966231952 182 dbSNP
rs976233494 185 dbSNP
rs868214622 190 dbSNP
rs1399723747 193 dbSNP
rs1156728382 196 dbSNP
rs1351426567 204 dbSNP
rs1441314377 210 dbSNP
rs1325145798 213 dbSNP
rs1432354350 216 dbSNP
rs777956719 221 dbSNP
rs567634363 223 dbSNP
rs536276212 224 dbSNP
rs1032233033 226 dbSNP
rs7694 231 dbSNP
rs1350283659 238 dbSNP
rs1222262203 244 dbSNP
rs914732638 261 dbSNP
rs1395008757 270 dbSNP
rs947577978 272 dbSNP
rs1251740121 273 dbSNP
rs990340473 282 dbSNP
rs1183404746 284 dbSNP
rs1311184348 284 dbSNP
rs1044651937 286 dbSNP
rs1469138659 290 dbSNP
rs906113762 303 dbSNP
rs200762327 305 dbSNP
rs188351625 306 dbSNP
rs1392289713 307 dbSNP
rs979730677 311 dbSNP
rs928551865 321 dbSNP
rs1467094979 323 dbSNP
rs558701413 332 dbSNP
rs575449229 342 dbSNP
rs1482950182 349 dbSNP
rs897006982 352 dbSNP
rs1356319933 353 dbSNP
rs1233125773 360 dbSNP
rs1271625352 364 dbSNP
rs1320679510 384 dbSNP
rs931150802 385 dbSNP
rs1180240305 392 dbSNP
rs1196908526 393 dbSNP
rs1258378827 409 dbSNP
rs1272872754 418 dbSNP
rs1425443310 420 dbSNP
rs994197948 430 dbSNP
rs1049650090 442 dbSNP
rs1259254365 443 dbSNP
rs1475328724 445 dbSNP
rs3093641 447 dbSNP
rs1007522762 450 dbSNP
rs1168459601 456 dbSNP
rs1160914016 471 dbSNP
rs1345456696 490 dbSNP
rs1017528414 498 dbSNP
rs1395609977 503 dbSNP
rs1408331646 507 dbSNP
rs1465257356 508 dbSNP
rs1300530781 516 dbSNP
rs1017487073 538 dbSNP
rs1414374565 540 dbSNP
rs3093642 547 dbSNP
rs975723923 548 dbSNP
rs1270144004 553 dbSNP
rs1338003018 555 dbSNP
rs1193643750 560 dbSNP
rs1281808131 562 dbSNP
rs1485823969 569 dbSNP
rs1209743465 570 dbSNP
rs1254914697 574 dbSNP
rs1448530184 576 dbSNP
rs1288335322 581 dbSNP
rs998200140 586 dbSNP
rs1372496867 589 dbSNP
rs758741122 617 dbSNP
rs566202303 618 dbSNP
rs914348135 620 dbSNP
rs956444197 621 dbSNP
rs573580512 623 dbSNP
rs1383184453 634 dbSNP
rs1318071683 640 dbSNP
rs758060344 644 dbSNP
rs1208322544 653 dbSNP
rs1304750175 665 dbSNP
rs1021393297 666 dbSNP
rs181244605 667 dbSNP
rs1483627113 669 dbSNP
rs1277815667 683 dbSNP
rs938916412 687 dbSNP
rs1053438 706 dbSNP
rs1251071580 711 dbSNP
rs1471467866 712 dbSNP
rs928311386 716 dbSNP
rs1260745144 717 dbSNP
rs959684075 720 dbSNP
rs897153047 723 dbSNP
rs930016697 729 dbSNP
rs1253474899 733 dbSNP
rs1048425092 734 dbSNP
rs75991893 742 dbSNP
rs1158405149 744 dbSNP
rs1454476174 744 dbSNP
rs1383291600 749 dbSNP
rs1443519194 753 dbSNP
rs1327174649 758 dbSNP
rs1370886012 760 dbSNP
rs1439604350 761 dbSNP
rs918505954 766 dbSNP
rs900357614 776 dbSNP
rs931141534 780 dbSNP
rs1215271410 781 dbSNP
rs1277768080 782 dbSNP
rs1467974723 790 dbSNP
rs1191874143 793 dbSNP
rs1434872393 795 dbSNP
rs751138365 806 dbSNP
rs1419701741 817 dbSNP
rs1048189862 819 dbSNP
rs1030288714 820 dbSNP
rs1362213302 821 dbSNP
rs551520178 824 dbSNP
rs1166094302 830 dbSNP
rs988480581 833 dbSNP
rs909313318 834 dbSNP
rs1460315111 837 dbSNP
rs1300363614 842 dbSNP
rs138543922 847 dbSNP
rs749300832 848 dbSNP
rs901879565 855 dbSNP
rs1280463342 856 dbSNP
rs997525500 863 dbSNP
rs1234979961 865 dbSNP
rs1217628906 868 dbSNP
rs1303748630 879 dbSNP
rs1219312000 885 dbSNP
rs532191232 886 dbSNP
rs979898034 888 dbSNP
rs892014357 890 dbSNP
rs1273796234 896 dbSNP
rs113840661 898 dbSNP
rs1248761178 899 dbSNP
rs927438956 905 dbSNP
rs1233190143 908 dbSNP
rs960230080 914 dbSNP
rs1012173429 917 dbSNP
rs550870250 920 dbSNP
rs929944507 922 dbSNP
rs1355565750 924 dbSNP
rs1021779921 927 dbSNP
rs1462102037 930 dbSNP
rs970196473 932 dbSNP
rs28667288 942 dbSNP
rs1293478214 943 dbSNP
rs149586841 943 dbSNP
rs1226336838 945 dbSNP
rs148873001 951 dbSNP
rs1387815141 957 dbSNP
rs1307997074 967 dbSNP
rs1226831606 978 dbSNP
rs567059491 994 dbSNP
rs1486664455 995 dbSNP
rs780476432 999 dbSNP
rs997391315 1000 dbSNP
rs796091396 1002 dbSNP
rs146975717 1007 dbSNP
rs191830261 1008 dbSNP
rs1388213946 1010 dbSNP
rs1420932889 1011 dbSNP
rs1428410285 1016 dbSNP
rs1169195253 1017 dbSNP
rs983936673 1021 dbSNP
rs558661369 1033 dbSNP
rs1387808513 1038 dbSNP
rs1295471191 1053 dbSNP
rs1313119727 1059 dbSNP
rs3093643 1061 dbSNP
rs1445626643 1068 dbSNP
rs1290376888 1071 dbSNP
rs1362631471 1073 dbSNP
rs9689 1081 dbSNP
rs1350148111 1085 dbSNP
rs555233925 1098 dbSNP
rs574992275 1103 dbSNP
rs968441144 1106 dbSNP
rs183256879 1112 dbSNP
rs1310660967 1114 dbSNP
rs1218432600 1115 dbSNP
rs1243034214 1115 dbSNP
rs933326486 1126 dbSNP
rs1187265444 1128 dbSNP
rs1255372045 1132 dbSNP
rs1455204893 1133 dbSNP
rs1053098516 1134 dbSNP
rs1394175784 1142 dbSNP
rs1412374469 1151 dbSNP
rs892063643 1153 dbSNP
rs769062914 1155 dbSNP
rs1429679627 1158 dbSNP
rs1318475480 1161 dbSNP
rs774681582 1167 dbSNP
rs1441821952 1168 dbSNP
rs1302724250 1172 dbSNP
rs1365818450 1173 dbSNP
rs1043318650 1179 dbSNP
rs951650141 1180 dbSNP
rs1207158883 1181 dbSNP
rs906066029 1190 dbSNP
rs1248266911 1195 dbSNP
rs1469276957 1199 dbSNP
rs1193788255 1200 dbSNP
rs1245643240 1225 dbSNP
rs1476719186 1231 dbSNP
rs1178611098 1242 dbSNP
rs984413695 1248 dbSNP
rs1156646737 1251 dbSNP
rs909862514 1252 dbSNP
rs1001699054 1254 dbSNP
rs1245604078 1258 dbSNP
rs1035439505 1261 dbSNP
rs1325072016 1268 dbSNP
rs942751288 1272 dbSNP
rs185879457 1273 dbSNP
rs190777401 1276 dbSNP
rs11818 1278 dbSNP
rs551912872 1287 dbSNP
rs1025283895 1299 dbSNP
rs564998452 1306 dbSNP
rs952462934 1311 dbSNP
rs3093644 1312 dbSNP
rs1051613432 1316 dbSNP
rs566302299 1319 dbSNP
rs1233142232 1320 dbSNP
rs539798733 1326 dbSNP
rs963849337 1330 dbSNP
rs1179821439 1335 dbSNP
rs976521346 1350 dbSNP
rs550756320 1391 dbSNP
rs767648317 1399 dbSNP
rs1318858132 1400 dbSNP
rs1475374279 1403 dbSNP
rs561141859 1404 dbSNP
rs1162620648 1416 dbSNP
rs374955154 1420 dbSNP
rs544949447 1421 dbSNP
rs529921264 1422 dbSNP
rs1270674081 1424 dbSNP
rs1354230955 1426 dbSNP
rs1034479335 1427 dbSNP
rs1314932259 1431 dbSNP
rs959794394 1433 dbSNP
rs989285259 1439 dbSNP
rs546891680 1442 dbSNP
rs1355496028 1444 dbSNP
rs183329645 1451 dbSNP
rs1025750594 1459 dbSNP
rs1273080410 1460 dbSNP
rs947370247 1461 dbSNP
rs1202592286 1465 dbSNP
rs538676201 1470 dbSNP
rs1335249310 1475 dbSNP
rs1485887892 1479 dbSNP
rs906072607 1480 dbSNP
rs1017227567 1483 dbSNP
rs1476346960 1485 dbSNP
rs866909545 1490 dbSNP
rs937499193 1500 dbSNP
rs1389641242 1504 dbSNP
rs1427864090 1512 dbSNP
rs941337878 1518 dbSNP
rs1175786292 1519 dbSNP
rs1376270529 1520 dbSNP
rs1395852752 1521 dbSNP
rs975449122 1525 dbSNP
rs1328765971 1528 dbSNP
rs922654612 1533 dbSNP
rs934042124 1534 dbSNP
rs1340882084 1535 dbSNP
rs1225482403 1538 dbSNP
rs186601461 1544 dbSNP
rs1261925033 1546 dbSNP
rs569051676 1547 dbSNP
rs913060606 1549 dbSNP
rs1199727571 1551 dbSNP
rs945939673 1558 dbSNP
rs1043324793 1564 dbSNP
rs1236407164 1570 dbSNP
rs1247291047 1571 dbSNP
rs1472071280 1582 dbSNP
rs537957122 1583 dbSNP
rs904446984 1588 dbSNP
rs3093658 1597 dbSNP
rs1395992939 1604 dbSNP
rs1465720718 1606 dbSNP
rs993953931 1611 dbSNP
rs138115560 1616 dbSNP
rs1401608868 1622 dbSNP
rs1320497876 1624 dbSNP
rs1419017200 1636 dbSNP
rs1432309524 1637 dbSNP
rs936974348 1641 dbSNP
rs1331383310 1642 dbSNP
rs368829657 1645 dbSNP
rs1232088199 1648 dbSNP
rs1457109525 1648 dbSNP
rs1157178997 1649 dbSNP
rs1055405792 1650 dbSNP
rs1205485013 1651 dbSNP
rs538924300 1652 dbSNP
rs116348266 1653 dbSNP
rs1401527769 1654 dbSNP
rs1333545265 1655 dbSNP
rs1463488385 1656 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuaUUCUGGUAGAAAAGGAGUu 5'
             |||||  ||   |||||| 
Target 5' -ucAAGAC--UC---UCCUCAa 3'
 		1 - 16
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_014313 | 3UTR | CUCUACACUGUGAAUAUUGCCUGGUGAUCAAGACUCUCCUCAAAGAAAUGACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_014313 | 3UTR | AUUGCCUGGUGAUCAAGACUCUCCUCAAAGAAAUGACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_014313 | 3UTR | GCCUGGUGAUCAAGACUCUCCUCAAAGAAAUGACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_014313 | 3UTR | AUAUUGCCUGGUGAUCAAGACUCUCCUCAAAGAAAUGACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_014313 | 3UTR | UUGCCUGGUGAUCAAGACUCUCCUCAAAGAAAUGACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000374358.4 | 3UTR | UCAAGACUCUCCUCAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-3915 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059544 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha 2 2
MIRT081703 ZNF507 zinc finger protein 507 2 2
MIRT083311 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT119046 SFT2D3 SFT2 domain containing 3 2 2
MIRT189381 TXLNA taxilin alpha 2 4
MIRT195895 C16ORF72 chromosome 16 open reading frame 72 2 6
MIRT223807 OXR1 oxidation resistance 1 2 2
MIRT292954 ZNF146 zinc finger protein 146 2 4
MIRT293949 RPL13A ribosomal protein L13a 2 6
MIRT300900 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT339332 SESN2 sestrin 2 2 2
MIRT349304 ZNF317 zinc finger protein 317 2 2
MIRT364736 TOR1B torsin family 1 member B 2 2
MIRT366233 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT384605 CLIC4 chloride intracellular channel 4 2 2
MIRT401745 HLA-DRA major histocompatibility complex, class II, DR alpha 2 2
MIRT443169 UBL3 ubiquitin like 3 2 2
MIRT444215 METTL12 methyltransferase like 12 2 2
MIRT444375 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT445340 TCEANC transcription elongation factor A N-terminal and central domain containing 2 2
MIRT445474 KDM6A lysine demethylase 6A 2 2
MIRT445598 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT445630 TMEM50A transmembrane protein 50A 2 2
MIRT446012 VNN1 vanin 1 2 2
MIRT446115 ASTN1 astrotactin 1 2 2
MIRT446248 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT446382 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT446940 ZMAT3 zinc finger matrin-type 3 2 2
MIRT446967 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT447178 PGRMC2 progesterone receptor membrane component 2 2 2
MIRT447209 APBB2 amyloid beta precursor protein binding family B member 2 2 2
MIRT447237 IHH indian hedgehog 2 2
MIRT447807 EMX1 empty spiracles homeobox 1 2 2
MIRT447853 RRP8 ribosomal RNA processing 8 2 4
MIRT448054 MMP15 matrix metallopeptidase 15 2 2
MIRT448094 RASD2 RASD family member 2 2 2
MIRT448704 KLHL11 kelch like family member 11 2 2
MIRT448851 FEM1C fem-1 homolog C 2 2
MIRT449488 ZBTB4 zinc finger and BTB domain containing 4 2 2
MIRT449785 C1orf109 chromosome 1 open reading frame 109 2 2
MIRT450774 PDE3A phosphodiesterase 3A 2 2
MIRT451124 ZNF99 zinc finger protein 99 2 2
MIRT452676 GPR156 G protein-coupled receptor 156 2 2
MIRT452888 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453188 ACSF2 acyl-CoA synthetase family member 2 2 2
MIRT453353 ZNF3 zinc finger protein 3 2 2
MIRT454502 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT454629 FAM83H family with sequence similarity 83 member H 2 2
MIRT455183 AGTRAP angiotensin II receptor associated protein 2 2
MIRT458204 FOXL2 forkhead box L2 2 2
MIRT458723 CES2 carboxylesterase 2 2 2
MIRT458942 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT460304 FLCN folliculin 2 2
MIRT460989 SYT7 synaptotagmin 7 2 2
MIRT461697 ZNF426 zinc finger protein 426 2 2
MIRT461903 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462193 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 2 2
MIRT462290 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463795 XPOT exportin for tRNA 2 2
MIRT464649 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 4
MIRT465911 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 4
MIRT465992 TMEM189 transmembrane protein 189 2 4
MIRT466302 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466575 TBC1D2B TBC1 domain family member 2B 2 2
MIRT470558 POU2F1 POU class 2 homeobox 1 2 2
MIRT471333 PERP PERP, TP53 apoptosis effector 2 2
MIRT471659 PALM2 paralemmin 2 2 2
MIRT472363 TSPAN1 tetraspanin 1 2 2
MIRT473468 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT474702 KIF3A kinesin family member 3A 2 2
MIRT476067 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT476077 GRB2 growth factor receptor bound protein 2 2 2
MIRT476423 GBA2 glucosylceramidase beta 2 2 2
MIRT476463 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT477877 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT478240 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT479460 CDK6 cyclin dependent kinase 6 2 2
MIRT481030 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT491496 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT497585 SLC23A1 solute carrier family 23 member 1 2 2
MIRT498542 TMEM30B transmembrane protein 30B 2 2
MIRT499263 NBPF11 NBPF member 11 2 2
MIRT504698 ZNF117 zinc finger protein 117 2 2
MIRT511288 KLHL15 kelch like family member 15 2 4
MIRT523121 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT529601 H1F0 H1 histone family member 0 2 2
MIRT533481 TRIM71 tripartite motif containing 71 2 2
MIRT535571 NUP37 nucleoporin 37 2 4
MIRT537869 EDA2R ectodysplasin A2 receptor 2 2
MIRT538010 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552681 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT554986 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT556659 KMT2D lysine methyltransferase 2D 2 4
MIRT557437 GTPBP2 GTP binding protein 2 2 2
MIRT560813 CRTAP cartilage associated protein 2 2
MIRT562115 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT563103 IFRD2 interferon related developmental regulator 2 2 2
MIRT574199 LMNB1 lamin B1 2 2
MIRT623920 FMNL3 formin like 3 2 2
MIRT626551 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2 2
MIRT645458 ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 2 2
MIRT649082 CACNA1B calcium voltage-gated channel subunit alpha1 B 2 2
MIRT659477 CLDN1 claudin 1 2 2
MIRT667950 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 2 2
MIRT701981 MIER3 MIER family member 3 2 2
MIRT708694 TFDP2 transcription factor Dp-2 2 2
MIRT709649 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710090 FAM229B family with sequence similarity 229 member B 2 2
MIRT718396 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT724972 TNS1 tensin 1 2 2
MIRT756050 HRH4 histamine receptor H4 2 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3915 Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-3915 Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-3915 Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3915 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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