miRTarBase - #MIRT445767


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pre-miRNA Information
pre-miRNA hsa-mir-4270   
Genomic Coordinates chr3: 15496239 - 15496308
Description Homo sapiens miR-4270 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4270
Sequence 11| UCAGGGAGUCAGGGGAGGGC |30
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs991570490 2 dbSNP
rs1417709982 10 dbSNP
rs960511282 12 dbSNP
rs928808979 14 dbSNP
rs1372156971 15 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CCND3   
Synonyms -
Description cyclin D3
Transcript NM_001136017   
Other Transcripts NM_001136125 , NM_001136126 , NM_001760   
Expression
Putative miRNA Targets on CCND3
3'UTR of CCND3
(miRNA target sites are highlighted)		 
>CCND3|NM_001136017|3'UTR
   1 CCCTGGAGAGGCCCTCTGGAGTGGCCACTAAGCAGAGGAGGGGCCGCTGCCACCCACCTCCCTGCCTCCAGGAACCACAC
  81 CACATCTAAGCCTGAAGGGGCGTCTGTTCCCCCTTCACAAAGCCCAAGGGATCTGGTCCTACCCATCCCCGCAGTGTGCA
 161 CTAAGGGGCCCGGCCAGCCATGTCTGCATTTCGGTGGCTAGTCAAGCTCCTCCTCCCTGCATCTGACCAGCAGCGCCTTT
 241 CCCAACTCTAGCTGGGGGTGGGCCAGGCTGATGGGACAGAATTGGATACATACACCAGCATTCCTTTTGAACGCCCCCCC
 321 CCACCCCTGGGGGCTCTCATGTTTTCAACTGCCAAAATGCTCTAGTGCCTTCTAAAGGTGTTGTCCCTTCTAGGGTTATT
 401 GCATTTGGATTGGGGTCCCTCTAAAATTTAATGCATGATAGACACATATGAGGGGGAATAGTCTAGATGGCTCCTCTCAG
 481 TACTTTGGAGGCCCCTATGTAGTCCGTGCTGACAGCTGCTCCTAGAGGGAGGGGCCTAGGCCTCAGCCAGAGAAGCTATA
 561 AATTCCTCTTTGCTTTGCTTTCTGCTCAGCTTCTCCTGTGTGATTGACAGCTTTGCTGCTGAAGGCTCATTTTAATTTAT
 641 TAATTGCTTTGAGCACAACTTTAAGAGGACATAATGGGGTCCTGGCCATCCCACAAGTGGTGGTAACCCTGGTGGTTGCT
 721 GTTTTCCTCCCTTCTGCTACTGGCAAAAGGATCTTTGTGGCCAAGGAGCTGCTATAGCCTGGGGTGGGGTCATGCCCTCC
 801 TCTCCCATTGTCCCTCTGCCCCATCCTCCAGCAGGGAAAATGCAGCAGGGATGCCCTGGAGGTGGCTGAGCCCCTGTCTA
 881 GAGAGGGAGGCAAGCCCTGTTGACACAGGTCTTTCCTAAGGCTGCAAGGTTTAGGCTGGTGGCCCAGGACCATCATCCTA
 961 CTGTAATAAAGATGATTGTGAAATAAAACTGGCTTTGGCTTCTTGGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cggGAGGGGACUGAGGGACu 5'
             ||||:|   ||||||| 
Target 5' aagCTCCTC---CTCCCTGc 3'
 204 - 220 154.00 -20.60
2 
miRNA  3' cgGGAGGGGACU-GAGGGACu 5'
            || |||   | ||||||| 
Target 5' tgCCACCC---ACCTCCCTGc 3'
 48 - 65 147.00 -20.90
3 
miRNA  3' cgGGAGGGGACUGAGGGACu 5'
            |:|: |:| :||::||| 
Target 5' ctCTTTGCTTTGCTTTCTGc 3'
 566 - 585 126.00 -15.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31967404 8 COSMIC
COSN31494652 16 COSMIC
COSN30530962 87 COSMIC
COSN31581974 97 COSMIC
COSN26636119 118 COSMIC
COSN31522636 137 COSMIC
COSN30158708 147 COSMIC
COSN22199142 223 COSMIC
COSN9783348 227 COSMIC
COSN20102833 313 COSMIC
COSN28872267 314 COSMIC
COSN29071729 323 COSMIC
COSN20462559 330 COSMIC
COSN31771085 505 COSMIC
COSN31546186 596 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs777109944 1 dbSNP
rs1216564413 5 dbSNP
rs748997652 6 dbSNP
rs1008510305 8 dbSNP
rs1298336020 14 dbSNP
rs545523358 18 dbSNP
rs1220920588 19 dbSNP
rs1321051204 21 dbSNP
rs576887815 22 dbSNP
rs755595501 25 dbSNP
rs745438885 26 dbSNP
rs1377305475 35 dbSNP
rs374760695 37 dbSNP
rs757191519 40 dbSNP
rs1229557938 42 dbSNP
rs3218103 45 dbSNP
rs1293678221 46 dbSNP
rs1238829036 47 dbSNP
rs1456909822 50 dbSNP
rs763981873 52 dbSNP
rs1161853201 53 dbSNP
rs758167818 54 dbSNP
rs1380129283 55 dbSNP
rs1157217950 57 dbSNP
rs1336848728 58 dbSNP
rs752943795 65 dbSNP
rs1253788403 74 dbSNP
rs1390207641 79 dbSNP
rs1190696147 80 dbSNP
rs543059644 83 dbSNP
rs1045110967 87 dbSNP
rs1244938617 95 dbSNP
rs897423308 99 dbSNP
rs759687476 101 dbSNP
rs543050471 102 dbSNP
rs1178616224 105 dbSNP
rs1404189823 106 dbSNP
rs1052227518 109 dbSNP
rs766938960 110 dbSNP
rs906928758 111 dbSNP
rs1237686210 112 dbSNP
rs1044541044 114 dbSNP
rs1367412828 119 dbSNP
rs1432851772 120 dbSNP
rs935200114 122 dbSNP
rs1349608197 125 dbSNP
rs925116555 129 dbSNP
rs773399793 131 dbSNP
rs1385756872 133 dbSNP
rs979510457 135 dbSNP
rs1338567387 136 dbSNP
rs1219594204 143 dbSNP
rs1280385489 147 dbSNP
rs948337233 149 dbSNP
rs964464521 150 dbSNP
rs911239855 151 dbSNP
rs1219343422 153 dbSNP
rs987184665 167 dbSNP
rs763419802 171 dbSNP
rs955654500 172 dbSNP
rs867972088 173 dbSNP
rs994410493 181 dbSNP
rs1242060492 184 dbSNP
rs574329101 185 dbSNP
rs1478605299 187 dbSNP
rs186181458 191 dbSNP
rs1370948158 192 dbSNP
rs962909465 193 dbSNP
rs924535212 203 dbSNP
rs1017094296 206 dbSNP
rs1464346859 209 dbSNP
rs975916042 210 dbSNP
rs1391006152 212 dbSNP
rs1399007795 213 dbSNP
rs1317653590 214 dbSNP
rs1325787911 215 dbSNP
rs1437053478 221 dbSNP
rs534906902 228 dbSNP
rs1285016966 229 dbSNP
rs966271704 234 dbSNP
rs565914747 235 dbSNP
rs1005997462 236 dbSNP
rs370734536 243 dbSNP
rs1202861621 245 dbSNP
rs1044754772 248 dbSNP
rs3218104 248 dbSNP
rs74774866 248 dbSNP
rs1013630426 256 dbSNP
rs896145821 261 dbSNP
rs954167492 262 dbSNP
rs1183236681 277 dbSNP
rs1414482043 278 dbSNP
rs1052341605 282 dbSNP
rs1158097801 287 dbSNP
rs1483634061 287 dbSNP
rs1257416372 291 dbSNP
rs1199163952 296 dbSNP
rs935231387 297 dbSNP
rs1257440424 300 dbSNP
rs1026924424 304 dbSNP
rs749074508 312 dbSNP
rs995495208 313 dbSNP
rs79272218 314 dbSNP
rs961622162 315 dbSNP
rs1043512985 316 dbSNP
rs879041589 316 dbSNP
rs1285838462 317 dbSNP
rs1356399210 318 dbSNP
rs942819722 319 dbSNP
rs1290199632 320 dbSNP
rs911260447 320 dbSNP
rs1044621490 321 dbSNP
rs892916288 322 dbSNP
rs1161692456 323 dbSNP
rs1289865858 323 dbSNP
rs3833667 323 dbSNP
rs538806926 323 dbSNP
rs60324721 323 dbSNP
rs1054111581 324 dbSNP
rs986830146 324 dbSNP
rs1340612082 328 dbSNP
rs955590003 329 dbSNP
rs1404058345 330 dbSNP
rs1247545998 335 dbSNP
rs1303668376 336 dbSNP
rs918586914 338 dbSNP
rs973001723 340 dbSNP
rs570065131 354 dbSNP
rs1479862925 355 dbSNP
rs962941045 360 dbSNP
rs1017126835 370 dbSNP
rs1195506853 376 dbSNP
rs554490762 383 dbSNP
rs944671418 385 dbSNP
rs1181859546 387 dbSNP
rs1472955292 390 dbSNP
rs773705624 394 dbSNP
rs1169108045 407 dbSNP
rs1374649338 410 dbSNP
rs1417822740 432 dbSNP
rs910374356 433 dbSNP
rs181262833 439 dbSNP
rs1454209581 440 dbSNP
rs1334142851 444 dbSNP
rs796238265 449 dbSNP
rs954115499 450 dbSNP
rs1343779911 454 dbSNP
rs1023840581 456 dbSNP
rs1425945475 457 dbSNP
rs1257257802 459 dbSNP
rs1200685158 460 dbSNP
rs1227162335 461 dbSNP
rs1256917088 465 dbSNP
rs1325956998 469 dbSNP
rs1013335428 471 dbSNP
rs920022664 473 dbSNP
rs974022108 477 dbSNP
rs1464119820 481 dbSNP
rs149025122 487 dbSNP
rs3218105 488 dbSNP
rs11552779 492 dbSNP
rs1263777881 495 dbSNP
rs1426593693 505 dbSNP
rs1210125115 506 dbSNP
rs1329203912 509 dbSNP
rs1429666582 516 dbSNP
rs1470777910 519 dbSNP
rs1030612313 528 dbSNP
rs1173812588 539 dbSNP
rs1457325063 540 dbSNP
rs769364880 540 dbSNP
rs999413584 549 dbSNP
rs1015812993 551 dbSNP
rs903758419 556 dbSNP
rs1360529941 559 dbSNP
rs1264845681 560 dbSNP
rs11552781 566 dbSNP
rs1382109532 582 dbSNP
rs1302471749 583 dbSNP
rs1347743290 595 dbSNP
rs1221985563 596 dbSNP
rs1242455357 598 dbSNP
rs1262736517 602 dbSNP
rs982095390 604 dbSNP
rs1342046551 607 dbSNP
rs1043545586 610 dbSNP
rs747739901 615 dbSNP
rs1484863431 625 dbSNP
rs1023122279 629 dbSNP
rs1269379585 630 dbSNP
rs1434070152 635 dbSNP
rs1481289455 635 dbSNP
rs547720067 636 dbSNP
rs1428176185 642 dbSNP
rs776899963 646 dbSNP
rs527958754 649 dbSNP
rs889617163 654 dbSNP
rs1051654595 667 dbSNP
rs1160685808 669 dbSNP
rs1342905064 670 dbSNP
rs9529 671 dbSNP
rs1294628763 672 dbSNP
rs1162006808 678 dbSNP
rs1403503469 683 dbSNP
rs545214043 685 dbSNP
rs892865649 691 dbSNP
rs1032762048 692 dbSNP
rs972699302 693 dbSNP
rs1305017599 694 dbSNP
rs941610682 703 dbSNP
rs762409757 708 dbSNP
rs1490802380 709 dbSNP
rs1220019425 728 dbSNP
rs11552785 730 dbSNP
rs910095407 735 dbSNP
rs3218106 740 dbSNP
rs1480783010 764 dbSNP
rs970670964 771 dbSNP
rs1369427521 773 dbSNP
rs902837375 779 dbSNP
rs1405249646 782 dbSNP
rs1024458526 784 dbSNP
rs1040078560 787 dbSNP
rs1163602553 789 dbSNP
rs1192997558 790 dbSNP
rs1387635828 792 dbSNP
rs527697377 793 dbSNP
rs1423245076 797 dbSNP
rs960416831 802 dbSNP
rs1448044656 813 dbSNP
rs768339846 825 dbSNP
rs1245860075 831 dbSNP
rs1051171 832 dbSNP
rs1030644717 834 dbSNP
rs1296660511 839 dbSNP
rs1409758880 841 dbSNP
rs1228970100 843 dbSNP
rs1190088486 850 dbSNP
rs944602982 857 dbSNP
rs1243654611 860 dbSNP
rs1464976549 862 dbSNP
rs889060379 864 dbSNP
rs1051186 872 dbSNP
rs1206254008 873 dbSNP
rs879739915 873 dbSNP
rs1050187102 876 dbSNP
rs1480067877 887 dbSNP
rs1183702581 889 dbSNP
rs749130363 897 dbSNP
rs999109988 900 dbSNP
rs903789585 904 dbSNP
rs1420747678 908 dbSNP
rs1412014411 917 dbSNP
rs534111328 922 dbSNP
rs1022669539 930 dbSNP
rs563241000 942 dbSNP
rs1358456579 955 dbSNP
rs1006803059 976 dbSNP
rs1227442451 977 dbSNP
rs3218107 978 dbSNP
rs1050933003 982 dbSNP
rs1283515338 989 dbSNP
rs866375719 1008 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cggGAGGGGACUGAGGGACu 5'
             ||||:|   ||||||| 
Target 5' aagCUCCUC---CUCCCUG- 3'
 		3 - 18
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000372991.4 | 3UTR | UCAAGCUCCUCCUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000372991.4 | 3UTR | UCAAGCUCCUCCUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
146 hsa-miR-4270 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT056076 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 2 2
MIRT057833 SLC30A7 solute carrier family 30 member 7 2 2
MIRT109295 TXLNG taxilin gamma 2 2
MIRT117521 MIDN midnolin 2 2
MIRT183504 BTG2 BTG anti-proliferation factor 2 2 2
MIRT258346 HOXA11 homeobox A11 2 6
MIRT275743 TFDP1 transcription factor Dp-1 2 2
MIRT284426 CAPN15 calpain 15 2 2
MIRT386430 CCL22 C-C motif chemokine ligand 22 2 2
MIRT443374 PLXNA2 plexin A2 2 2
MIRT445251 SEMA5A semaphorin 5A 2 2
MIRT445767 CCND3 cyclin D3 2 2
MIRT447231 ABI2 abl interactor 2 2 2
MIRT451224 ZNF444 zinc finger protein 444 2 2
MIRT451433 TJP3 tight junction protein 3 2 4
MIRT451959 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452006 FKBP5 FK506 binding protein 5 2 2
MIRT452300 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT452717 DTHD1 death domain containing 1 2 2
MIRT453361 ZNF3 zinc finger protein 3 2 2
MIRT453458 GLG1 golgi glycoprotein 1 2 2
MIRT453832 SAA1 serum amyloid A1 2 2
MIRT453928 COMMD5 COMM domain containing 5 2 4
MIRT454312 ZNF134 zinc finger protein 134 2 2
MIRT454493 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454836 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT455142 TBC1D25 TBC1 domain family member 25 2 2
MIRT455922 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT456163 TTF2 transcription termination factor 2 2 2
MIRT456395 KLHL12 kelch like family member 12 2 2
MIRT456786 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT457164 MXRA7 matrix remodeling associated 7 2 2
MIRT457190 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT457415 RPL36 ribosomal protein L36 2 2
MIRT457630 UPK3BL uroplakin 3B like 1 2 2
MIRT458720 VPS39 VPS39, HOPS complex subunit 2 2
MIRT458745 CES2 carboxylesterase 2 2 2
MIRT459269 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT459490 CCL11 C-C motif chemokine ligand 11 2 2
MIRT460319 SH3RF1 SH3 domain containing ring finger 1 2 2
MIRT461005 SYT7 synaptotagmin 7 2 2
MIRT461579 SCO1 SCO1, cytochrome c oxidase assembly protein 2 4
MIRT461820 SNAP23 synaptosome associated protein 23 2 2
MIRT463332 ZFHX3 zinc finger homeobox 3 2 2
MIRT463449 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464272 VCL vinculin 2 2
MIRT464895 UBALD1 UBA like domain containing 1 2 2
MIRT465556 TOB2 transducer of ERBB2, 2 2 2
MIRT466360 THBS1 thrombospondin 1 2 2
MIRT466956 STAT3 signal transducer and activator of transcription 3 2 2
MIRT467321 SPATA2 spermatogenesis associated 2 2 2
MIRT467440 SND1 staphylococcal nuclease and tudor domain containing 1 2 2
MIRT467823 SLC29A2 solute carrier family 29 member 2 2 2
MIRT471173 PHB2 prohibitin 2 2 2
MIRT471397 PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2 2
MIRT471754 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 2
MIRT471846 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT472020 NPTXR neuronal pentraxin receptor 2 2
MIRT472224 NGFR nerve growth factor receptor 2 2
MIRT472439 NBL1 neuroblastoma 1, DAN family BMP antagonist 2 2
MIRT472541 NACC1 nucleus accumbens associated 1 2 2
MIRT473195 MINOS1-NBL1 MINOS1-NBL1 readthrough 2 2
MIRT473211 MINK1 misshapen like kinase 1 2 2
MIRT473668 MARCKSL1 MARCKS like 1 2 2
MIRT474852 KHSRP KH-type splicing regulatory protein 2 2
MIRT474939 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT477330 EPHA2 EPH receptor A2 2 2
MIRT477395 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT477466 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT477974 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 2 2
MIRT478331 DDN dendrin 2 2
MIRT479481 CDK2 cyclin dependent kinase 2 2 2
MIRT481212 ATXN7L3B ataxin 7 like 3B 2 2
MIRT481263 ATXN7L3 ataxin 7 like 3 2 2
MIRT481409 ASXL1 additional sex combs like 1, transcriptional regulator 2 2
MIRT482051 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT482396 AEN apoptosis enhancing nuclease 2 2
MIRT483160 PCSK2 proprotein convertase subtilisin/kexin type 2 2 7
MIRT483370 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT483520 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 4
MIRT484059 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT487075 CLASP1 cytoplasmic linker associated protein 1 2 4
MIRT487421 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT488359 PAX2 paired box 2 2 2
MIRT488592 ST7L suppression of tumorigenicity 7 like 2 2
MIRT489556 SOX11 SRY-box 11 2 4
MIRT489804 KRT80 keratin 80 2 4
MIRT489865 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 2 2
MIRT490014 KIFC2 kinesin family member C2 2 2
MIRT490036 PCSK4 proprotein convertase subtilisin/kexin type 4 2 2
MIRT491070 ACVR1B activin A receptor type 1B 2 2
MIRT494016 DUSP9 dual specificity phosphatase 9 2 2
MIRT494816 AKAP11 A-kinase anchoring protein 11 2 2
MIRT495991 LTBP2 latent transforming growth factor beta binding protein 2 2 2
MIRT496272 SLC2A13 solute carrier family 2 member 13 2 2
MIRT500454 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT507989 BCL2L13 BCL2 like 13 2 4
MIRT509713 ANKRD23 ankyrin repeat domain 23 2 2
MIRT527984 TSLP thymic stromal lymphopoietin 2 2
MIRT530448 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT531235 FANCC Fanconi anemia complementation group C 2 2
MIRT534590 RPL28 ribosomal protein L28 2 2
MIRT535990 MED28 mediator complex subunit 28 2 4
MIRT537280 GABRA5 gamma-aminobutyric acid type A receptor alpha5 subunit 2 2
MIRT539924 DUSP28 dual specificity phosphatase 28 2 2
MIRT554711 RNF146 ring finger protein 146 2 2
MIRT558962 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT568497 ARHGDIA Rho GDP dissociation inhibitor alpha 2 2
MIRT568875 LY6H lymphocyte antigen 6 family member H 2 2
MIRT568987 CACNA1C calcium voltage-gated channel subunit alpha1 C 2 2
MIRT569990 TMEM184A transmembrane protein 184A 2 2
MIRT570485 THRA thyroid hormone receptor, alpha 2 2
MIRT572826 MYO1C myosin IC 2 2
MIRT608199 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT613220 CCDC85C coiled-coil domain containing 85C 2 4
MIRT629782 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT635332 RASSF4 Ras association domain family member 4 2 2
MIRT653632 SLC30A3 solute carrier family 30 member 3 2 2
MIRT664572 GUF1 GUF1 homolog, GTPase 2 2
MIRT667855 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668820 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT671274 ETFDH electron transfer flavoprotein dehydrogenase 2 2
MIRT681448 CIITA class II major histocompatibility complex transactivator 2 2
MIRT684817 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT685861 ANGEL1 angel homolog 1 2 2
MIRT688812 CAPZB capping actin protein of muscle Z-line beta subunit 2 2
MIRT691198 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT696947 CERK ceramide kinase 2 2
MIRT699741 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT701259 NUP35 nucleoporin 35 2 2
MIRT701935 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT703332 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT705519 ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 2 2
MIRT706065 PKD1 polycystin 1, transient receptor potential channel interacting 2 2
MIRT713238 SV2B synaptic vesicle glycoprotein 2B 2 2
MIRT714670 CHRNE cholinergic receptor nicotinic epsilon subunit 2 2
MIRT715001 TSPAN11 tetraspanin 11 2 2
MIRT715356 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT715971 FADS3 fatty acid desaturase 3 2 2
MIRT719585 FNBP4 formin binding protein 4 2 2
MIRT719667 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT723360 ASCL2 achaete-scute family bHLH transcription factor 2 2 2
MIRT734985 GADD45A growth arrest and DNA damage inducible alpha 2 0
MIRT735022 MMP19 matrix metallopeptidase 19 3 0
MIRT737359 SATB2 SATB homeobox 2 3 0
MIRT756223 MCM3 minichromosome maintenance complex component 3 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miR-4270 Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4270 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4270 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (total RNA)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-4270 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4270 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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