miRTarBase - #MIRT446012


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pre-miRNA Information
pre-miRNA hsa-mir-3915   
Genomic Coordinates chrX: 32583656 - 32583752
Description Homo sapiens miR-3915 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3915
Sequence 21| UUGAGGAAAAGAUGGUCUUAUU |42
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs997323565 10 dbSNP
rs1192161547 15 dbSNP
rs1255075246 19 dbSNP
rs1452812574 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol VNN1   
Synonyms HDLCQ8, Tiff66
Description vanin 1
Transcript NM_004666   
Expression
Putative miRNA Targets on VNN1
3'UTR of VNN1
(miRNA target sites are highlighted)		 
>VNN1|NM_004666|3'UTR
   1 AATATTGACTTTTTCTCTTTTTTATTTGGGATAATTTAAAAAATGATGGATGAGAAAAGAAAGATTGGTCCGGGTTAATA
  81 TTATCCTCTAGTATAAGTGAATTACTAGTTTCTCTTTATTTAGACAAACACACACACACCAGATAATATAAACTTAATAA
 161 ATTATCTGTTAATGTAGATTTTATTTAAAAAACTATATTTGAACATTGGTCTTTCTTGGACGTGAGCTAATTATATCAAA
 241 TAAGTATCACAAATCTTTTACGCAGAAGAAATAAAAACTACGGGTAGAAAACATAAGAACTATCATAAAATTTACTTACA
 321 AGGAGGCTGCTCTTGTTACCACTTTTATTATATTACGTATCACTTATTCAGCTCTGCTGAAAATTTCCAATGACTTTGTT
 401 TGTTTGCTCTTTTTGTTTTTTACCTAAACAATACATTTTGATTCTCTTGTGGGTTGATAATGTCTCCCCAAAATTTACAT
 481 GTTGAAGCACCTCAGAATGTGACTGTATTTGGAGACAGGGTCTTTAAAGAGGTAAAATAAGGTCATTAGGATAGACCCTA
 561 ATTCAATATGACTGATGATCATAAAAGAAGAGGCGAGTAGGGCACAACAGGCACAAAGGGAGACCATAAGGAGACACAGA
 641 GGAAGGACAACTCTTTACAAGCTAAGAAGAGAGGGCCTCAGAAGAAACCAACCCTGCCAACACCTTGATCTTGGACTTCC
 721 AGCCTCCAAAACTATGAGAAATAAATTTCTATTGTTTAAGTCACCCAGTCCATGGTACTTTGTTAGGCAGCCCTGGCAAA
 801 TGAATCAAAGACCCATTCCTGTTCCTCTCCCCACCACTACTGTTTTCTACTGTAATCTGAAGCTTCAACAAAAGGCTTAC
 881 CTGGTAAGAATATTCAGCTGGTCTGGGTCCTCAAGACTCCAATAGACACTCTTAGAGAAGGATTGCTGATGGATTGATAG
 961 TGAAACCATTAGATCATTGAATTCCTCTGGAATTAGAAAACCAGAGAGTCCCATTTTAAGAAATTAGATATTTAATATAG
1041 CATTGTGTGTTCTATTTTAGTAACAGCAGAATCTCTTGACATTACACAACTCAGTGAAACAACATCATTTAAGCCAAAAT
1121 ATCTCCCAACTGACTGATAGACTCTGAGCACTAATATCATAGTGCTGTGATGATGGACAATTACATAGTACCGATAACAG
1201 CCATGCACTGTGCAAAGCATGCCCTTCTGCACAGGAGAGCAAGGCACTTGCAGTAGTGATCTATGCCAGCAAAACATCAT
1281 TTTGAGACAAACATTTTTGTGGCAGATGTTTTTCCTAAAAAGTACTATATCATCCAAGAAATATTTGAGTAAAATCCCTT
1361 GTTCTTTTGGGTGACATTAACTGACATTTGCTTTTTTTCAAGACCTAATAGAAAATAAGAAAGCCCATAATGTATTTAGA
1441 AACAGGAATCCTCAGAGCAATTCTCTGTATTCTCATATAATTTCAATGTAAAACAGAAAACATATTGATGTGTTGGTGAT
1521 AGGCTTGAATTATTAAAAACTTCAAAAACATCCTAAGTGTTTCTTTTTTGCTCAACGTTGTCAACTATAGTAGGTCTCCC
1601 TTGTGGTGTAATGAATTGCCCCCAAACTATTATCTTAAAACAACAAACATTTATTATCTTATAGCATTTCTGAGGGTCAG
1681 GATCTGGGACTGGCTTAGTGGAGTTGTTCTGGATCAGGGCCTTTGGAAAGTTGTAGTTAACTTGTCCCCAGGGCTGCCAT
1761 CATCTCAAGGCTCGGGTGGGGCTGGAGAAAATCTGCTTCTCAGCTCACTCACGGCGGTTGCCAGGCCTCCATTCTTTAGG
1841 ATGCTAGAAAAACTTTCATAAAATGTCATCTGGCTTCTCCTAGAGCAATGATACTGAGAGAGAAAGCACATGAGAGAAAG
1921 AGCGAGGGAACTTGGATGTAAGCCACAGTCTTTGAAAACCTAATCACAGAAGTGACATCTCTTCTTCCACATGATGTTGG
2001 TCACATGGACCAACAATGGCACAACGTGGACAGAATCAAACAGAGTTGAGAATATCAGGAGGTGGGGCTTCATGGGGGCC
2081 ATTTTGGATGCTATCATAGTGAATATATGTATTTATATTTATATCTGTATATATTGCAATGTAATTTAAAAAATAGGATT
2161 GTTTTCCTTTTCTTTTTGCTATATGTGATATGTATTTCAAAATACACTCCCAATAGTTACGTCTGAAAAGCACTACACTA
2241 AAAAACTTTCTATACATTGAATAATTAAATTAAATAATCTAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuaUUCU-GGUA--GAAAAGGAGuu 5'
             |||| ||||  || ||||||  
Target 5' tcaAAGACCCATTCCTGTTCCTCtc 3'
 805 - 829 149.00 -14.60
2 
miRNA  3' uuAUUCUGGUAG-AAAAGGAGuu 5'
            | |||:|||:   ||||||  
Target 5' caTTAGATCATTGAATTCCTCtg 3'
 967 - 989 140.00 -15.10
3 
miRNA  3' uuAUU--CUGGUA---GAAAAGGAGUu 5'
            |||  || |||   |||||::||| 
Target 5' atTAACTGA-CATTTGCTTTTTTTCAa 3'
 1376 - 1401 133.00 -11.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30486881 13 COSMIC
COSN31490400 36 COSMIC
COSN30111909 57 COSMIC
COSN1325162 61 COSMIC
COSN15663764 72 COSMIC
COSN30103280 74 COSMIC
COSN22619033 85 COSMIC
COSN20075586 144 COSMIC
COSN25604380 174 COSMIC
COSN20379771 179 COSMIC
COSN26324594 361 COSMIC
COSN8493677 1214 COSMIC
COSN31528975 1338 COSMIC
COSN6304151 1374 COSMIC
COSN31579067 1439 COSMIC
COSN21018529 1503 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs748998558 1 dbSNP
rs1014804616 7 dbSNP
rs1181550531 9 dbSNP
rs1038171116 10 dbSNP
rs1005086556 11 dbSNP
rs890314040 17 dbSNP
rs1364339442 18 dbSNP
rs1316199974 26 dbSNP
rs1383700670 28 dbSNP
rs1385412766 31 dbSNP
rs777682378 38 dbSNP
rs1422389558 39 dbSNP
rs756026350 43 dbSNP
rs1392743023 44 dbSNP
rs1163633390 46 dbSNP
rs752958845 47 dbSNP
rs374785173 49 dbSNP
rs754942344 50 dbSNP
rs373053171 52 dbSNP
rs996305313 55 dbSNP
rs34315074 59 dbSNP
rs1263402989 60 dbSNP
rs982650317 65 dbSNP
rs1366459725 66 dbSNP
rs900486430 71 dbSNP
rs778268520 72 dbSNP
rs375285135 78 dbSNP
rs1278835305 85 dbSNP
rs927838423 86 dbSNP
rs1201473622 92 dbSNP
rs1249660303 94 dbSNP
rs936898168 97 dbSNP
rs767012738 103 dbSNP
rs1192356331 115 dbSNP
rs1371309273 116 dbSNP
rs1479027081 123 dbSNP
rs1271152142 134 dbSNP
rs1230044146 135 dbSNP
rs1468426981 140 dbSNP
rs980704399 147 dbSNP
rs1389808840 154 dbSNP
rs1042647256 157 dbSNP
rs969444819 158 dbSNP
rs548796871 159 dbSNP
rs1413517311 165 dbSNP
rs1352694366 176 dbSNP
rs551264540 177 dbSNP
rs918103466 187 dbSNP
rs989628262 192 dbSNP
rs1269683838 195 dbSNP
rs777586612 201 dbSNP
rs992973325 202 dbSNP
rs185536951 205 dbSNP
rs958470419 208 dbSNP
rs1030711995 209 dbSNP
rs1008985079 214 dbSNP
rs926955313 215 dbSNP
rs954887231 221 dbSNP
rs1029177223 222 dbSNP
rs973011718 228 dbSNP
rs755172752 233 dbSNP
rs899145797 236 dbSNP
rs1310270526 244 dbSNP
rs181600163 250 dbSNP
rs369060433 261 dbSNP
rs542339425 262 dbSNP
rs886490390 263 dbSNP
rs1303145820 266 dbSNP
rs1344297106 270 dbSNP
rs572999313 272 dbSNP
rs1414131528 278 dbSNP
rs1030189520 279 dbSNP
rs1057252331 281 dbSNP
rs1231384460 282 dbSNP
rs1237972941 287 dbSNP
rs536840137 293 dbSNP
rs111606313 296 dbSNP
rs149463425 296 dbSNP
rs927805638 296 dbSNP
rs1223106203 304 dbSNP
rs1272680033 305 dbSNP
rs1290993258 306 dbSNP
rs780258202 317 dbSNP
rs73559706 323 dbSNP
rs1000828504 324 dbSNP
rs543367728 329 dbSNP
rs902534496 330 dbSNP
rs577715815 336 dbSNP
rs45493896 350 dbSNP
rs956579960 353 dbSNP
rs923662006 356 dbSNP
rs45558340 357 dbSNP
rs973147432 360 dbSNP
rs962987154 362 dbSNP
rs1350129813 363 dbSNP
rs954854914 390 dbSNP
rs75251762 394 dbSNP
rs1459418305 398 dbSNP
rs756025392 398 dbSNP
rs1304478755 399 dbSNP
rs866546978 407 dbSNP
rs553558276 409 dbSNP
rs1044593 414 dbSNP
rs546731974 416 dbSNP
rs1314230064 425 dbSNP
rs963701357 429 dbSNP
rs1207304029 430 dbSNP
rs1418280890 432 dbSNP
rs1405574036 434 dbSNP
rs754127653 435 dbSNP
rs1194280146 437 dbSNP
rs1258579973 442 dbSNP
rs1004857832 444 dbSNP
rs189963917 446 dbSNP
rs1183391187 447 dbSNP
rs764507420 448 dbSNP
rs577199813 449 dbSNP
rs974539093 450 dbSNP
rs137919943 458 dbSNP
rs886459146 464 dbSNP
rs1373130477 470 dbSNP
rs1461079937 481 dbSNP
rs143517222 482 dbSNP
rs1252646827 484 dbSNP
rs1211828554 489 dbSNP
rs1002987145 492 dbSNP
rs906359866 493 dbSNP
rs1269311479 495 dbSNP
rs41286180 497 dbSNP
rs1215751556 500 dbSNP
rs1315478610 505 dbSNP
rs1044946455 512 dbSNP
rs1000961907 516 dbSNP
rs1225374109 518 dbSNP
rs1257932134 521 dbSNP
rs902500025 529 dbSNP
rs1020976448 533 dbSNP
rs1241668590 541 dbSNP
rs1466568824 542 dbSNP
rs1220206793 556 dbSNP
rs1187581686 561 dbSNP
rs1014250418 566 dbSNP
rs1427355310 569 dbSNP
rs41286178 574 dbSNP
rs915129471 576 dbSNP
rs1055789538 577 dbSNP
rs938159887 581 dbSNP
rs1054124257 583 dbSNP
rs553316097 586 dbSNP
rs1289334898 587 dbSNP
rs573000318 592 dbSNP
rs557480016 594 dbSNP
rs551250319 595 dbSNP
rs185858832 601 dbSNP
rs1261543624 606 dbSNP
rs1177922975 621 dbSNP
rs923172581 627 dbSNP
rs767292438 632 dbSNP
rs922090677 633 dbSNP
rs559413030 635 dbSNP
rs1485179426 641 dbSNP
rs974674677 642 dbSNP
rs1270401577 647 dbSNP
rs974898571 648 dbSNP
rs1198206130 652 dbSNP
rs964508873 662 dbSNP
rs1402180823 665 dbSNP
rs1159582113 671 dbSNP
rs1344468254 673 dbSNP
rs1451522901 676 dbSNP
rs963894705 677 dbSNP
rs1032206020 688 dbSNP
rs1346195305 696 dbSNP
rs549129171 697 dbSNP
rs148822391 710 dbSNP
rs979493214 710 dbSNP
rs1224615775 715 dbSNP
rs1248773140 725 dbSNP
rs1021365047 730 dbSNP
rs1315567891 736 dbSNP
rs1013549578 738 dbSNP
rs563907394 739 dbSNP
rs1485154752 742 dbSNP
rs1266254654 744 dbSNP
rs138410117 745 dbSNP
rs1033907806 747 dbSNP
rs577703561 766 dbSNP
rs371857725 772 dbSNP
rs1417122919 782 dbSNP
rs1211189544 785 dbSNP
rs1347686583 786 dbSNP
rs564105289 790 dbSNP
rs1165349663 816 dbSNP
rs1366137455 818 dbSNP
rs1279157091 829 dbSNP
rs1002442569 830 dbSNP
rs1372559822 847 dbSNP
rs1443185298 849 dbSNP
rs898652656 856 dbSNP
rs1371592586 857 dbSNP
rs1230419605 861 dbSNP
rs1038545870 865 dbSNP
rs545693399 870 dbSNP
rs1221003665 875 dbSNP
rs1035729751 880 dbSNP
rs1288959121 881 dbSNP
rs1204736854 899 dbSNP
rs1359701290 899 dbSNP
rs1231982620 902 dbSNP
rs369696330 903 dbSNP
rs552186787 904 dbSNP
rs770746409 905 dbSNP
rs1171982261 915 dbSNP
rs1161654377 921 dbSNP
rs530708559 923 dbSNP
rs893647391 924 dbSNP
rs1328390343 925 dbSNP
rs1353000492 928 dbSNP
rs1454866855 932 dbSNP
rs2745426 935 dbSNP
rs150089794 940 dbSNP
rs796430357 942 dbSNP
rs1244410486 945 dbSNP
rs1300494871 946 dbSNP
rs142588295 949 dbSNP
rs571290134 957 dbSNP
rs943290362 973 dbSNP
rs1271775861 979 dbSNP
rs925104742 986 dbSNP
rs1051416672 989 dbSNP
rs1485531957 993 dbSNP
rs376377765 1002 dbSNP
rs1205248910 1003 dbSNP
rs147750769 1006 dbSNP
rs932988911 1008 dbSNP
rs1181650180 1009 dbSNP
rs921666371 1009 dbSNP
rs974917821 1027 dbSNP
rs59593516 1028 dbSNP
rs1343810283 1030 dbSNP
rs549012726 1031 dbSNP
rs909399884 1035 dbSNP
rs45575344 1037 dbSNP
rs960726097 1040 dbSNP
rs58642458 1045 dbSNP
rs1002410013 1050 dbSNP
rs879434507 1054 dbSNP
rs1035948675 1058 dbSNP
rs549888019 1068 dbSNP
rs1430738261 1069 dbSNP
rs1017149648 1072 dbSNP
rs1337847220 1074 dbSNP
rs1224940295 1082 dbSNP
rs1415371435 1085 dbSNP
rs970478088 1090 dbSNP
rs1023024781 1096 dbSNP
rs772404676 1104 dbSNP
rs745904577 1106 dbSNP
rs1201560511 1108 dbSNP
rs893625104 1109 dbSNP
rs1447522249 1113 dbSNP
rs1004343979 1123 dbSNP
rs533087827 1128 dbSNP
rs887291010 1132 dbSNP
rs145516154 1137 dbSNP
rs1200356039 1138 dbSNP
rs1428883090 1139 dbSNP
rs1468509896 1140 dbSNP
rs999395700 1144 dbSNP
rs1160656501 1154 dbSNP
rs1411433011 1156 dbSNP
rs1047442835 1162 dbSNP
rs902398517 1163 dbSNP
rs997701076 1170 dbSNP
rs182045945 1171 dbSNP
rs527297413 1175 dbSNP
rs932965913 1183 dbSNP
rs1406278405 1184 dbSNP
rs45547932 1189 dbSNP
rs943259022 1191 dbSNP
rs542995993 1192 dbSNP
rs1166079462 1193 dbSNP
rs1043683806 1197 dbSNP
rs1038768570 1198 dbSNP
rs1416379145 1201 dbSNP
rs1282115651 1205 dbSNP
rs1490846031 1208 dbSNP
rs574165827 1209 dbSNP
rs1268360537 1210 dbSNP
rs1479576293 1213 dbSNP
rs1184320692 1222 dbSNP
rs1364715377 1231 dbSNP
rs941810334 1235 dbSNP
rs913753263 1237 dbSNP
rs1184706713 1241 dbSNP
rs1157301733 1245 dbSNP
rs1483595916 1246 dbSNP
rs1368028791 1252 dbSNP
rs992239421 1259 dbSNP
rs1250784448 1267 dbSNP
rs1303236140 1275 dbSNP
rs772046129 1276 dbSNP
rs1384705116 1277 dbSNP
rs867820186 1280 dbSNP
rs1479356883 1289 dbSNP
rs557164732 1292 dbSNP
rs757305408 1296 dbSNP
rs1266640765 1297 dbSNP
rs1361505083 1308 dbSNP
rs981706954 1310 dbSNP
rs45614931 1314 dbSNP
rs574301853 1314 dbSNP
rs962686443 1317 dbSNP
rs1197742431 1319 dbSNP
rs915923437 1320 dbSNP
rs1251550972 1321 dbSNP
rs1333985536 1322 dbSNP
rs1437561206 1327 dbSNP
rs1180127012 1330 dbSNP
rs189576317 1340 dbSNP
rs1445760449 1342 dbSNP
rs957726219 1344 dbSNP
rs1004882759 1349 dbSNP
rs951563461 1351 dbSNP
rs778750607 1357 dbSNP
rs997272456 1358 dbSNP
rs778431144 1360 dbSNP
rs901626407 1362 dbSNP
rs1336198079 1370 dbSNP
rs1306522111 1371 dbSNP
rs1389939673 1377 dbSNP
rs1393177248 1378 dbSNP
rs1319960972 1383 dbSNP
rs1229736331 1399 dbSNP
rs575175982 1399 dbSNP
rs1252052500 1402 dbSNP
rs756489665 1411 dbSNP
rs1030188386 1420 dbSNP
rs1245346624 1427 dbSNP
rs753169828 1428 dbSNP
rs900159379 1429 dbSNP
rs1254728048 1430 dbSNP
rs1392850537 1437 dbSNP
rs1162073298 1443 dbSNP
rs903534687 1449 dbSNP
rs541187534 1457 dbSNP
rs1363631218 1458 dbSNP
rs1005890820 1462 dbSNP
rs41286176 1471 dbSNP
rs373542304 1472 dbSNP
rs1461157649 1478 dbSNP
rs183703581 1491 dbSNP
rs1407987851 1502 dbSNP
rs141786886 1505 dbSNP
rs1470151614 1508 dbSNP
rs1335944409 1510 dbSNP
rs1376903774 1512 dbSNP
rs928810051 1518 dbSNP
rs1045999853 1522 dbSNP
rs1269064889 1526 dbSNP
rs1213724358 1539 dbSNP
rs191148868 1540 dbSNP
rs549972102 1542 dbSNP
rs915909533 1546 dbSNP
rs939208459 1548 dbSNP
rs926671843 1550 dbSNP
rs990517020 1553 dbSNP
rs957401841 1555 dbSNP
rs1254701852 1558 dbSNP
rs779358261 1559 dbSNP
rs1187673205 1562 dbSNP
rs924668207 1564 dbSNP
rs909912344 1570 dbSNP
rs977493294 1571 dbSNP
rs1351113106 1576 dbSNP
rs1278676315 1577 dbSNP
rs1236617743 1588 dbSNP
rs966504648 1590 dbSNP
rs1030155770 1593 dbSNP
rs1333009660 1594 dbSNP
rs997440645 1602 dbSNP
rs1304468977 1606 dbSNP
rs533175515 1607 dbSNP
rs964948961 1609 dbSNP
rs1017532603 1610 dbSNP
rs187050349 1619 dbSNP
rs951757022 1622 dbSNP
rs1384311290 1627 dbSNP
rs1398264276 1629 dbSNP
rs887461867 1631 dbSNP
rs1047492994 1632 dbSNP
rs528544890 1634 dbSNP
rs1029822100 1648 dbSNP
rs367866200 1649 dbSNP
rs964208879 1650 dbSNP
rs1401741425 1656 dbSNP
rs1217091258 1657 dbSNP
rs1260685304 1664 dbSNP
rs45541240 1676 dbSNP
rs1007345499 1682 dbSNP
rs1467923888 1683 dbSNP
rs527273687 1690 dbSNP
rs903503448 1699 dbSNP
rs1193921634 1701 dbSNP
rs1022421198 1705 dbSNP
rs765866861 1706 dbSNP
rs1159697830 1707 dbSNP
rs762371675 1712 dbSNP
rs1417880630 1723 dbSNP
rs1250661024 1725 dbSNP
rs1305025606 1731 dbSNP
rs948916953 1735 dbSNP
rs1009481161 1741 dbSNP
rs375394480 1742 dbSNP
rs1054725598 1746 dbSNP
rs1375930571 1747 dbSNP
rs45577038 1757 dbSNP
rs529585961 1758 dbSNP
rs1352158936 1759 dbSNP
rs939161968 1761 dbSNP
rs1293305580 1762 dbSNP
rs905045836 1773 dbSNP
rs2745425 1774 dbSNP
rs934116767 1779 dbSNP
rs183812909 1782 dbSNP
rs1379525869 1785 dbSNP
rs1281263635 1790 dbSNP
rs1165444885 1794 dbSNP
rs115801877 1801 dbSNP
rs1404870073 1811 dbSNP
rs964590625 1812 dbSNP
rs922804007 1813 dbSNP
rs45549237 1815 dbSNP
rs572389908 1816 dbSNP
rs1316905736 1819 dbSNP
rs1455033727 1825 dbSNP
rs45580133 1836 dbSNP
rs985875941 1844 dbSNP
rs746051977 1850 dbSNP
rs1173863418 1857 dbSNP
rs1287238453 1858 dbSNP
rs1026017579 1865 dbSNP
rs1022054834 1867 dbSNP
rs537498462 1870 dbSNP
rs1456304495 1873 dbSNP
rs535864823 1878 dbSNP
rs892150944 1883 dbSNP
rs1392883424 1885 dbSNP
rs1169100941 1892 dbSNP
rs1475467857 1893 dbSNP
rs906909810 1897 dbSNP
rs1410733464 1910 dbSNP
rs1170298598 1914 dbSNP
rs1398519485 1916 dbSNP
rs193201805 1922 dbSNP
rs1013473233 1923 dbSNP
rs188311958 1924 dbSNP
rs1258029703 1946 dbSNP
rs905013334 1948 dbSNP
rs751733400 1953 dbSNP
rs556506166 1976 dbSNP
rs1055097088 1991 dbSNP
rs1263610998 1999 dbSNP
rs936301305 2002 dbSNP
rs1185406037 2005 dbSNP
rs903189417 2009 dbSNP
rs2064312 2010 dbSNP
rs1193168211 2016 dbSNP
rs778411161 2025 dbSNP
rs929941906 2026 dbSNP
rs1402031210 2027 dbSNP
rs922662341 2031 dbSNP
rs1320895094 2043 dbSNP
rs975543680 2045 dbSNP
rs1312580388 2046 dbSNP
rs1277113452 2048 dbSNP
rs1337971099 2050 dbSNP
rs1041301071 2054 dbSNP
rs943180357 2055 dbSNP
rs956585636 2056 dbSNP
rs910412939 2057 dbSNP
rs1198632468 2062 dbSNP
rs1447609070 2065 dbSNP
rs978893993 2068 dbSNP
rs985103543 2077 dbSNP
rs1330529875 2078 dbSNP
rs968879281 2079 dbSNP
rs951979432 2081 dbSNP
rs1418249920 2082 dbSNP
rs914952836 2086 dbSNP
rs1160744248 2088 dbSNP
rs759040392 2091 dbSNP
rs1166073071 2093 dbSNP
rs1297037005 2096 dbSNP
rs45472892 2097 dbSNP
rs547502436 2098 dbSNP
rs147897760 2102 dbSNP
rs1330260317 2103 dbSNP
rs1186902221 2106 dbSNP
rs1034713449 2108 dbSNP
rs971689135 2109 dbSNP
rs1003410149 2116 dbSNP
rs1484598206 2121 dbSNP
rs756755473 2129 dbSNP
rs572077193 2136 dbSNP
rs1266966134 2140 dbSNP
rs1024450438 2151 dbSNP
rs1233886069 2157 dbSNP
rs568024091 2159 dbSNP
rs547844945 2160 dbSNP
rs1437302336 2162 dbSNP
rs753083846 2168 dbSNP
rs1377913789 2172 dbSNP
rs1270900548 2176 dbSNP
rs777715220 2178 dbSNP
rs1163429948 2179 dbSNP
rs894628562 2188 dbSNP
rs1384799004 2196 dbSNP
rs888304554 2198 dbSNP
rs1377445524 2206 dbSNP
rs45550335 2211 dbSNP
rs1000322579 2213 dbSNP
rs903411999 2214 dbSNP
rs563595278 2220 dbSNP
rs901167331 2221 dbSNP
rs550110668 2230 dbSNP
rs1231815986 2236 dbSNP
rs1259083953 2244 dbSNP
rs998120745 2245 dbSNP
rs1177271265 2246 dbSNP
rs755322664 2249 dbSNP
rs1442557221 2260 dbSNP
rs1040181560 2261 dbSNP
rs765780377 2269 dbSNP
rs762241803 2286 dbSNP
rs942831435 2292 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000367928.4 | 3UTR | UCAAGACUCCAAUAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000367928.4 | 3UTR | UCAAGACUCCAAUAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-3915 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059544 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha 2 2
MIRT081703 ZNF507 zinc finger protein 507 2 2
MIRT083311 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT119046 SFT2D3 SFT2 domain containing 3 2 2
MIRT189381 TXLNA taxilin alpha 2 4
MIRT195895 C16ORF72 chromosome 16 open reading frame 72 2 6
MIRT223807 OXR1 oxidation resistance 1 2 2
MIRT292954 ZNF146 zinc finger protein 146 2 4
MIRT293949 RPL13A ribosomal protein L13a 2 6
MIRT300900 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT339332 SESN2 sestrin 2 2 2
MIRT349304 ZNF317 zinc finger protein 317 2 2
MIRT364736 TOR1B torsin family 1 member B 2 2
MIRT366233 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT384605 CLIC4 chloride intracellular channel 4 2 2
MIRT401745 HLA-DRA major histocompatibility complex, class II, DR alpha 2 2
MIRT443169 UBL3 ubiquitin like 3 2 2
MIRT444215 METTL12 methyltransferase like 12 2 2
MIRT444375 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT445340 TCEANC transcription elongation factor A N-terminal and central domain containing 2 2
MIRT445474 KDM6A lysine demethylase 6A 2 2
MIRT445598 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT445630 TMEM50A transmembrane protein 50A 2 2
MIRT446012 VNN1 vanin 1 2 2
MIRT446115 ASTN1 astrotactin 1 2 2
MIRT446248 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT446382 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT446940 ZMAT3 zinc finger matrin-type 3 2 2
MIRT446967 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT447178 PGRMC2 progesterone receptor membrane component 2 2 2
MIRT447209 APBB2 amyloid beta precursor protein binding family B member 2 2 2
MIRT447237 IHH indian hedgehog 2 2
MIRT447807 EMX1 empty spiracles homeobox 1 2 2
MIRT447853 RRP8 ribosomal RNA processing 8 2 4
MIRT448054 MMP15 matrix metallopeptidase 15 2 2
MIRT448094 RASD2 RASD family member 2 2 2
MIRT448704 KLHL11 kelch like family member 11 2 2
MIRT448851 FEM1C fem-1 homolog C 2 2
MIRT449488 ZBTB4 zinc finger and BTB domain containing 4 2 2
MIRT449785 C1orf109 chromosome 1 open reading frame 109 2 2
MIRT450774 PDE3A phosphodiesterase 3A 2 2
MIRT451124 ZNF99 zinc finger protein 99 2 2
MIRT452676 GPR156 G protein-coupled receptor 156 2 2
MIRT452888 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453188 ACSF2 acyl-CoA synthetase family member 2 2 2
MIRT453353 ZNF3 zinc finger protein 3 2 2
MIRT454502 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT454629 FAM83H family with sequence similarity 83 member H 2 2
MIRT455183 AGTRAP angiotensin II receptor associated protein 2 2
MIRT458204 FOXL2 forkhead box L2 2 2
MIRT458723 CES2 carboxylesterase 2 2 2
MIRT458942 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT460304 FLCN folliculin 2 2
MIRT460989 SYT7 synaptotagmin 7 2 2
MIRT461697 ZNF426 zinc finger protein 426 2 2
MIRT461903 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462193 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 2 2
MIRT462290 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463795 XPOT exportin for tRNA 2 2
MIRT464649 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 4
MIRT465911 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 4
MIRT465992 TMEM189 transmembrane protein 189 2 4
MIRT466302 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466575 TBC1D2B TBC1 domain family member 2B 2 2
MIRT470558 POU2F1 POU class 2 homeobox 1 2 2
MIRT471333 PERP PERP, TP53 apoptosis effector 2 2
MIRT471659 PALM2 paralemmin 2 2 2
MIRT472363 TSPAN1 tetraspanin 1 2 2
MIRT473468 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT474702 KIF3A kinesin family member 3A 2 2
MIRT476067 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT476077 GRB2 growth factor receptor bound protein 2 2 2
MIRT476423 GBA2 glucosylceramidase beta 2 2 2
MIRT476463 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT477877 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT478240 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT479460 CDK6 cyclin dependent kinase 6 2 2
MIRT481030 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT491496 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT497585 SLC23A1 solute carrier family 23 member 1 2 2
MIRT498542 TMEM30B transmembrane protein 30B 2 2
MIRT499263 NBPF11 NBPF member 11 2 2
MIRT504698 ZNF117 zinc finger protein 117 2 2
MIRT511288 KLHL15 kelch like family member 15 2 4
MIRT523121 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT529601 H1F0 H1 histone family member 0 2 2
MIRT533481 TRIM71 tripartite motif containing 71 2 2
MIRT535571 NUP37 nucleoporin 37 2 4
MIRT537869 EDA2R ectodysplasin A2 receptor 2 2
MIRT538010 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552681 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT554986 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT556659 KMT2D lysine methyltransferase 2D 2 4
MIRT557437 GTPBP2 GTP binding protein 2 2 2
MIRT560813 CRTAP cartilage associated protein 2 2
MIRT562115 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT563103 IFRD2 interferon related developmental regulator 2 2 2
MIRT574199 LMNB1 lamin B1 2 2
MIRT623920 FMNL3 formin like 3 2 2
MIRT626551 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2 2
MIRT645458 ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 2 2
MIRT649082 CACNA1B calcium voltage-gated channel subunit alpha1 B 2 2
MIRT659477 CLDN1 claudin 1 2 2
MIRT667950 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 2 2
MIRT701981 MIER3 MIER family member 3 2 2
MIRT708694 TFDP2 transcription factor Dp-2 2 2
MIRT709649 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710090 FAM229B family with sequence similarity 229 member B 2 2
MIRT718396 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT724972 TNS1 tensin 1 2 2
MIRT756050 HRH4 histamine receptor H4 2 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3915 Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-3915 Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-3915 Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3915 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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