miRTarBase - #MIRT446119


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pre-miRNA Information
pre-miRNA hsa-mir-516b-1   
Genomic Coordinates chr19: 53736845 - 53736934
Synonyms MIRN516-4, MIRN516B-1, MIRN516B1, MIR516B1
Description Homo sapiens miR-516b-1 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-516b-2   
Genomic Coordinates chr19: 53725442 - 53725526
Synonyms MIRN516-3, MIRN516B-2, MIRN516B2, MIR516B2
Description Homo sapiens miR-516b-2 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-516b-3p
Sequence 56| UGCUUCCUUUCAGAGGGU |73
Evidence Experimental
Experiments Array-cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1413434631 1 dbSNP
rs746170707 2 dbSNP
rs1312744198 2 dbSNP
rs752101959 3 dbSNP
rs770077784 4 dbSNP
rs1193425541 6 dbSNP
rs953142850 7 dbSNP
rs1020245150 7 dbSNP
rs775845942 11 dbSNP
rs1402471980 11 dbSNP
rs760158839 15 dbSNP
rs78861479 16 dbSNP
rs765933705 16 dbSNP
Putative Targets

Gene Information
Gene Symbol ASTN1   
Synonyms ASTN
Description astrotactin 1
Transcript NM_004319   
Other Transcripts NM_207108   
Expression
Putative miRNA Targets on ASTN1
3'UTR of ASTN1
(miRNA target sites are highlighted)		 
>ASTN1|NM_004319|3'UTR
   1 CACCATAAGGCCAGGGAGCTGCTGCCAGAATGAAGTAGGAAAGAGGAGGGATCCATCTGGGTTGGTCTGTGGATTTTTAA
  81 TATTTTTTAATGGAACATGAAAACCTCCACAGCAACATCGAAACCAGGGAGAAAGTGATCCTTGCTCCCTGCAGAACTTC
 161 TTCAGTATGATGTTCTCCATCTGCATGATTGGGAAATCTGCCAGCCAGTGGCTTCATGCAGTGCCATATTTCTTTAGAGG
 241 ATTACTTTGGGGTTTGCTTTGCCATTAATTTGTTCCATTCATTTTTTTTTCCCTGAGAAGTTTACCAAAATGCTCAAGAG
 321 CTCTGCCGTGCTCCCCATGAAAAGTCTATTAAGTAGGCACCCTGTGCTCACTCAGTTCCTAAATCCATTGCAACTGGGAG
 401 CAGAGGTGAGGCCAGAAAGTTGTTAGGCCTGCCGCAGGCCCCACCCTCAAGCATTCCTCAGGAAGCGTCTCACTCTGGGA
 481 GCCTTGGCCCTGCTCACAGAGAGAGACAATAGAAAATTGAGGAAGGTGGCCCTTGTCTGTGTCTCCTGGTTTTCTTCCTA
 561 GGCCTTGCTATCACTATTTCCATACCCGAAAGGTGAAACCAGCTTTCATTATAGGCCCCAGTGGGCCACTTGGGTTTTGA
 641 GATCCTTCCTTATTTTAAGCCAGGACTGGGATTAAATCTCCCTCTGTCAGATCTCTGTCCCTTCCTCTGAACAACATGAT
 721 CTTTGAGAGGGAACAAGATGCCATCTGTCAACTGCACCTTCAGAAAAGTCTACCTGGGAGACTAGTTAGCAGTCCACATT
 801 CAAGAGGAGACTTGGAGTTTATTGTTTTTTAAAAAAACCATGCTTCCTTTGGATAGACTTCTCCAGCCTACCAATATATA
 881 TCCATGTGCCTGGATTATCTTTAACCCCCACACCTCTTACCTTGGACAGGTAAGGCTTGGCCGATGTCTGATTGGGACCA
 961 GGAGGGGTCAACACTTTCATATCAGTGTTACAGTGAACTAAAGCTATTATTGATCACAAAAAACTTCTGTTCATCCCCAC
1041 CTTGCTAAATTTGCTTGTGTTGCTAGTTTTGCAAATCGTTTCTCTGATGACCATAAGCAGGAGGATTCCACCATGGTCAC
1121 TGCCCATCCAGTCACAGGGATTCTGTGTAGGGAAGCACCACTGATTGCAGTTAACATCTAGAGTGTTGTTTCCATCCCAC
1201 TGCCCAAGCATTGGCATGGTCATGAATGGTGGCCCAGCCAACAGGAAGCCCAGCCTTTCAGAAAGAGCCTGGCAAGGCCC
1281 TGTTGACTAGCAATGGCCTTAGCTGTCCCACACAACTCAGTGGCCTGAACACACACCTTCAGCCACCATGCCTTTGACCA
1361 GGGCTCCTCATCTGGAAACATATGAGAAAGGTCAGCAAACAGATGCAAGACCTATAAGGCTAGTCATTGAGCTATATTGG
1441 TTTTTTTTCTAAATAGTAGTAGTGACAGATAACATTTATTGAGTGCTTGCTGTATGCCAGGCGCTGATGTAAGCACTTTA
1521 GGTATCATTGAATTCTCACAGCAACTCCTGAGGAAAGTGCTATTCTTGTCTCCATTTTAGTGTTGAGGAAAACGAGGCAA
1601 AGAGAGGTTATACAACTTGCCTCAAATCCCTTGTGCACTGTAACTCACACTGAGTTTCAGTGTGATTTCAGGCTGTTGGT
1681 CTCCAGGGCACAGGATCTTAGCTACTCTGGGATACCCAGTTCTGTTTTCAGTATCATCTGGCACACAACTGTCCAAGCTC
1761 TCAGCCCCACAGGGAACCTGCCCAGAGAGCTTTACCTTTCCCAAGCATCTGTGGCATGGACATGTCCTCTGTGCAGTGGA
1841 AGGAGGAGGGGCGAAAGTACGCCCTTAGCCTTTGGAGCTAGAGCACCCTTGGGACCCCTAGTTCCACTGCACATGGCCCT
1921 CCTCCCCACCCTCATGACTGGGAAGGAAGCCTGTGATGAGGCTGAGATAAAGCACAGGGTGGTTTCACTCTCCTCTCTCC
2001 TTCTTTCCAAACACTGAAGGATTTATTTCAAACTCTCTAATGCACCTGCCTCAGAGATTCCCCTACTTTCAAAGCAAAGA
2081 TCAGCAGAAAAATTGGCTGTCCCACCTGTGGCAAATGCTGGAGCCTCAGTTAAAGTGCCTCAAGGGGCAAATATTTCACC
2161 ATTGCCAGAGAAGATGTGACAGGCCAATCAGACAGGGCCCAGAGCATCTCTTTGCTGCTACTGTTTTGCCATCCTTCTAT
2241 TCATATCTGTGCAGAACACGGTGTTTTAAGCTTGAGTGAAAGGAGGGTGAGGCTGCCGATGCCTTCCTGCCCAGAAGTGG
2321 ATGATGTGGGAGTTGACAGGCCAGGGAGAGGGTGAAGCAGGTATCAGAGTCACTCCTCTGTACCCTCTCCTTCTGTTTTT
2401 ATTTTAGGCACACTATCTTCCTCTCTCCTATCTTTCCCTCAGTCTCCCAAGTTCCTCTACCTTCTTTATCTTTGTCTTTT
2481 ACTTCTTCTTTCTGTGACCCTCCTTTTTTGGCCTCCTCTTTCCCCAAGACTTTCTTCCTCCTGTTTCTCGTTGAGTTCTC
2561 CCCACTGAATGTGTGTATGTATGTACACACACACACACGTGTGCACACACAATGCACACAACTCCTATGACTGGCTCCTA
2641 CTTACATTCAAGTTAAAAAGGCTGATATGAACAGGGCAGGGGAAAATCTTAGGATGGTTGTACAATTGACTGGAGGATTT
2721 TTTCCCCTTGGAAGACACTATTGATCTCAACCTGCTGACTTTTCCTAATGCTTACCTGAAGGAACCCATCCTGGCTAGAA
2801 AGGGTGATGGTACTGGACCGGTATTCAACCTTGAGTTTTCAAGCTGCCAAACAGGTCTTAAGGGAGGTGCTTATATCCCA
2881 CCAACACTCTCCCAGCTCCCATGTCCCCAAGACCTCTGGAGTTTCCTCTTGAATGTACATGAACCACTGTAATAGCATTA
2961 GACTTTTAATTGAGTGTGCAATCGTTTTCCATGGAGTTTGGTCCGTTCATTATTTTTTAGTTAACTACACTTCTTGATAT
3041 TCAAATGTTCTATTAAAAAAACTGAGTATGAAGAAAAACACTTTACTACTGCAGAAGGAAGAAAGAATATAATATGACCA
3121 TCTTCAGGTATAACAGTGTTGTTTAAAAGAGAATTATTGTATGATTATAAAAGATGAAATAATTAACTGAATAATAAAAC
3201 AAAGCTATTAGTAAGCATTGAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugGGAG-ACU-----UUCCUUCGu 5'
            |||| |||     |||||||| 
Target 5' acCCTCATGACTGGGAAGGAAGCc 3'
 1928 - 1951 156.00 -20.30
2 
miRNA  3' ugGGAGACUUUCCUUCGu 5'
            ||||    ||||||| 
Target 5' ttCCTC----AGGAAGCg 3'
 454 - 467 146.00 -16.00
3 
miRNA  3' ugGGAGACUUUCCUUCGu 5'
            :|| || |:|||||| 
Target 5' atTCTGTGTAGGGAAGCa 3'
 1140 - 1157 144.00 -17.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30468258 4 COSMIC
COSN28678236 19 COSMIC
COSN28677945 20 COSMIC
COSN26967017 25 COSMIC
COSN26967016 28 COSMIC
COSN7186066 32 COSMIC
COSN30109009 43 COSMIC
COSN26577001 44 COSMIC
COSN30449561 46 COSMIC
COSN31508702 57 COSMIC
COSN31494048 64 COSMIC
COSN30474563 72 COSMIC
COSN28793065 99 COSMIC
COSN30108324 103 COSMIC
COSN13495412 120 COSMIC
COSN30454371 128 COSMIC
COSN30466218 147 COSMIC
COSN31501947 150 COSMIC
COSN31577870 169 COSMIC
COSN31610608 178 COSMIC
COSN30493545 187 COSMIC
COSN15661487 230 COSMIC
COSN28881908 282 COSMIC
COSN29239482 323 COSMIC
COSN25606826 328 COSMIC
COSN6009664 419 COSMIC
COSN26621344 439 COSMIC
COSN31569872 838 COSMIC
COSN1414619 852 COSMIC
COSN16715573 899 COSMIC
COSN26552149 911 COSMIC
COSN9366986 946 COSMIC
COSN30169659 1028 COSMIC
COSN19658848 1048 COSMIC
COSN26504690 1066 COSMIC
COSN30174240 1077 COSMIC
COSN19658567 1078 COSMIC
COSN31535683 1122 COSMIC
COSN8636878 1218 COSMIC
COSN22654232 1231 COSMIC
COSN23521059 1233 COSMIC
COSN32065702 1418 COSMIC
COSN29484785 1441 COSMIC
COSN17706632 1472 COSMIC
COSN22573817 1503 COSMIC
COSN6009663 1703 COSMIC
COSN17345043 1923 COSMIC
COSN16303964 1942 COSMIC
COSN5198825 2128 COSMIC
COSN31778067 2131 COSMIC
COSN7186065 2205 COSMIC
COSN28201702 2319 COSMIC
COSN20968698 2337 COSMIC
COSN27901169 2383 COSMIC
COSN17930041 2388 COSMIC
COSN17925741 2389 COSMIC
COSN19122652 2541 COSMIC
COSN27451815 2585 COSMIC
COSN16040379 2631 COSMIC
COSN20090409 2659 COSMIC
COSN15053885 2714 COSMIC
COSN25626795 2715 COSMIC
COSN26464949 2831 COSMIC
COSN8322943 2900 COSMIC
COSN14873361 2911 COSMIC
COSN31537870 2937 COSMIC
COSN31523612 3038 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs200991545 5 dbSNP
rs748957256 9 dbSNP
rs1292898304 10 dbSNP
rs758538695 11 dbSNP
rs1381302426 13 dbSNP
rs769290089 14 dbSNP
rs771250301 17 dbSNP
rs879675526 18 dbSNP
rs1362270465 19 dbSNP
rs1348998352 26 dbSNP
rs745410803 28 dbSNP
rs1232003616 30 dbSNP
rs1399281170 32 dbSNP
rs1310060245 48 dbSNP
rs1308597758 49 dbSNP
rs561493560 50 dbSNP
rs1328182294 51 dbSNP
rs1230754065 73 dbSNP
rs541870703 74 dbSNP
rs998911704 78 dbSNP
rs950513828 79 dbSNP
rs75385838 88 dbSNP
rs902870665 89 dbSNP
rs1051447887 93 dbSNP
rs923128967 97 dbSNP
rs975955432 99 dbSNP
rs1216761254 102 dbSNP
rs1228874205 106 dbSNP
rs1432012143 117 dbSNP
rs1198579704 118 dbSNP
rs965134639 119 dbSNP
rs1017689388 120 dbSNP
rs1157114120 125 dbSNP
rs528148259 133 dbSNP
rs1359926291 137 dbSNP
rs1268278130 141 dbSNP
rs1432673333 147 dbSNP
rs144312834 149 dbSNP
rs1387045969 150 dbSNP
rs1385069798 154 dbSNP
rs957399841 155 dbSNP
rs546011684 160 dbSNP
rs1302203899 161 dbSNP
rs1331481519 165 dbSNP
rs1422328648 172 dbSNP
rs1039517398 185 dbSNP
rs765854117 188 dbSNP
rs760057727 202 dbSNP
rs1031879637 217 dbSNP
rs1352575221 218 dbSNP
rs1427354178 222 dbSNP
rs941192151 223 dbSNP
rs999085729 226 dbSNP
rs909259147 241 dbSNP
rs1487757529 245 dbSNP
rs1209772253 247 dbSNP
rs907368088 256 dbSNP
rs1046288040 258 dbSNP
rs1419434735 259 dbSNP
rs577011940 262 dbSNP
rs557200965 268 dbSNP
rs1185252253 269 dbSNP
rs1379885484 276 dbSNP
rs1479033992 280 dbSNP
rs950774288 285 dbSNP
rs1013102515 290 dbSNP
rs200547682 291 dbSNP
rs971584705 291 dbSNP
rs547372915 292 dbSNP
rs1267395463 295 dbSNP
rs1375674922 304 dbSNP
rs1447077714 306 dbSNP
rs1308429485 319 dbSNP
rs1013011780 327 dbSNP
rs1244636791 328 dbSNP
rs777277604 331 dbSNP
rs1054918054 333 dbSNP
rs550493479 335 dbSNP
rs1197142739 337 dbSNP
rs1238016002 338 dbSNP
rs957586912 344 dbSNP
rs1179177804 348 dbSNP
rs1254127669 349 dbSNP
rs1270821794 351 dbSNP
rs1033154935 360 dbSNP
rs1216235778 363 dbSNP
rs1463000081 375 dbSNP
rs908901968 387 dbSNP
rs1399279888 393 dbSNP
rs1047667897 409 dbSNP
rs929181446 410 dbSNP
rs902838844 411 dbSNP
rs868517241 419 dbSNP
rs1312898289 424 dbSNP
rs761947935 433 dbSNP
rs976283328 434 dbSNP
rs1352213201 435 dbSNP
rs997853526 441 dbSNP
rs1467635804 451 dbSNP
rs1424855879 452 dbSNP
rs1483083714 456 dbSNP
rs1182504752 457 dbSNP
rs1259715590 465 dbSNP
rs139590812 466 dbSNP
rs74127249 467 dbSNP
rs909757028 471 dbSNP
rs772954940 474 dbSNP
rs1172320415 482 dbSNP
rs1357068764 484 dbSNP
rs957347605 489 dbSNP
rs1191938783 492 dbSNP
rs1302861650 496 dbSNP
rs1376750498 497 dbSNP
rs1031661978 503 dbSNP
rs998825540 507 dbSNP
rs1049605231 517 dbSNP
rs1299710853 523 dbSNP
rs972032230 524 dbSNP
rs1311763950 530 dbSNP
rs771582264 532 dbSNP
rs1211090663 533 dbSNP
rs1282510755 535 dbSNP
rs929374088 536 dbSNP
rs1013494716 537 dbSNP
rs1216046662 545 dbSNP
rs57121166 549 dbSNP
rs1055265838 557 dbSNP
rs971385460 583 dbSNP
rs1200526784 585 dbSNP
rs916153131 586 dbSNP
rs1318496797 587 dbSNP
rs80121532 588 dbSNP
rs1417299780 592 dbSNP
rs539999372 593 dbSNP
rs528725666 596 dbSNP
rs1047407685 605 dbSNP
rs1301573110 609 dbSNP
rs17378620 614 dbSNP
rs1370624131 617 dbSNP
rs532300061 618 dbSNP
rs207460685 622 dbSNP
rs1446800565 634 dbSNP
rs537319043 638 dbSNP
rs1305872063 643 dbSNP
rs1351834132 652 dbSNP
rs1401667723 653 dbSNP
rs1239512808 661 dbSNP
rs1286906831 665 dbSNP
rs1447453219 672 dbSNP
rs1217871768 675 dbSNP
rs1040323051 685 dbSNP
rs943193339 691 dbSNP
rs1244728368 695 dbSNP
rs1488050293 704 dbSNP
rs749289760 714 dbSNP
rs910407952 716 dbSNP
rs1029437087 718 dbSNP
rs146301964 719 dbSNP
rs936058136 731 dbSNP
rs899528208 734 dbSNP
rs1163317020 735 dbSNP
rs1018202500 736 dbSNP
rs924717364 741 dbSNP
rs1177108826 743 dbSNP
rs1188030151 757 dbSNP
rs548168896 763 dbSNP
rs977352687 772 dbSNP
rs1418719675 780 dbSNP
rs1352975974 785 dbSNP
rs1405958628 788 dbSNP
rs149339146 794 dbSNP
rs115235726 797 dbSNP
rs1321094432 798 dbSNP
rs6425398 807 dbSNP
rs1201641125 817 dbSNP
rs897882749 824 dbSNP
rs1256360418 831 dbSNP
rs1177657173 836 dbSNP
rs1232902877 837 dbSNP
rs1470865860 838 dbSNP
rs959115184 838 dbSNP
rs1462482148 839 dbSNP
rs528431071 840 dbSNP
rs1310906930 847 dbSNP
rs1005743349 856 dbSNP
rs1329419078 858 dbSNP
rs887489406 863 dbSNP
rs915953585 864 dbSNP
rs1329820840 867 dbSNP
rs6413830 868 dbSNP
rs746280569 871 dbSNP
rs1336702187 873 dbSNP
rs1283746042 874 dbSNP
rs115739603 877 dbSNP
rs543135309 878 dbSNP
rs1040674895 884 dbSNP
rs574604604 885 dbSNP
rs1029405927 886 dbSNP
rs889043762 897 dbSNP
rs1439262223 905 dbSNP
rs976537129 906 dbSNP
rs1453422415 909 dbSNP
rs963698657 913 dbSNP
rs560886266 914 dbSNP
rs752830203 915 dbSNP
rs1017919308 918 dbSNP
rs1421881106 923 dbSNP
rs1477680604 928 dbSNP
rs1054193701 930 dbSNP
rs778682546 935 dbSNP
rs190495479 942 dbSNP
rs924664660 943 dbSNP
rs1384665406 946 dbSNP
rs888345546 958 dbSNP
rs977514730 967 dbSNP
rs1295022224 974 dbSNP
rs1338405277 979 dbSNP
rs950074920 995 dbSNP
rs917286190 999 dbSNP
rs1340958951 1006 dbSNP
rs1198384848 1008 dbSNP
rs906397486 1012 dbSNP
rs1485729813 1016 dbSNP
rs1212447624 1020 dbSNP
rs1045792511 1023 dbSNP
rs1256696821 1024 dbSNP
rs765483316 1026 dbSNP
rs755100127 1028 dbSNP
rs1375159812 1032 dbSNP
rs894573853 1035 dbSNP
rs1172247038 1036 dbSNP
rs754447333 1055 dbSNP
rs1017202225 1056 dbSNP
rs755884678 1061 dbSNP
rs1358155145 1066 dbSNP
rs984256935 1071 dbSNP
rs1312275088 1077 dbSNP
rs766767514 1078 dbSNP
rs926198137 1084 dbSNP
rs139685796 1086 dbSNP
rs116396998 1091 dbSNP
rs867759890 1100 dbSNP
rs867249158 1101 dbSNP
rs1485796588 1103 dbSNP
rs184624929 1104 dbSNP
rs901491252 1109 dbSNP
rs574319658 1110 dbSNP
rs1198660735 1113 dbSNP
rs1253855081 1116 dbSNP
rs1007655326 1124 dbSNP
rs1455799842 1127 dbSNP
rs577291141 1131 dbSNP
rs557229215 1133 dbSNP
rs1379779114 1134 dbSNP
rs1358974986 1138 dbSNP
rs1452906678 1145 dbSNP
rs10913265 1147 dbSNP
rs1387097837 1148 dbSNP
rs1384839367 1151 dbSNP
rs1420508075 1153 dbSNP
rs1054308261 1168 dbSNP
rs999984006 1169 dbSNP
rs903048696 1174 dbSNP
rs1371269530 1175 dbSNP
rs1365096980 1188 dbSNP
rs1161761294 1191 dbSNP
rs543547509 1194 dbSNP
rs1459445006 1208 dbSNP
rs568760538 1211 dbSNP
rs1239190169 1215 dbSNP
rs1192319238 1221 dbSNP
rs150601187 1222 dbSNP
rs1213457417 1231 dbSNP
rs767209146 1236 dbSNP
rs1274203533 1241 dbSNP
rs1469944947 1245 dbSNP
rs1177027403 1247 dbSNP
rs1426569401 1248 dbSNP
rs1184134789 1254 dbSNP
rs534579218 1260 dbSNP
rs976925675 1265 dbSNP
rs7513341 1275 dbSNP
rs1265020443 1276 dbSNP
rs1394978902 1276 dbSNP
rs1194018667 1277 dbSNP
rs1490080946 1279 dbSNP
rs917342267 1294 dbSNP
rs1289068930 1309 dbSNP
rs1328836855 1313 dbSNP
rs1372222907 1320 dbSNP
rs910992552 1326 dbSNP
rs1308603247 1330 dbSNP
rs560876589 1334 dbSNP
rs1233225087 1350 dbSNP
rs952510479 1351 dbSNP
rs1211116148 1363 dbSNP
rs1025538983 1364 dbSNP
rs367962684 1366 dbSNP
rs797000018 1373 dbSNP
rs1266573037 1379 dbSNP
rs1250945958 1383 dbSNP
rs937349484 1384 dbSNP
rs910130183 1395 dbSNP
rs532062462 1396 dbSNP
rs1254170946 1399 dbSNP
rs1474149725 1409 dbSNP
rs578207461 1416 dbSNP
rs1024731870 1418 dbSNP
rs1280489095 1419 dbSNP
rs558126272 1422 dbSNP
rs1168349895 1425 dbSNP
rs1400928848 1427 dbSNP
rs768210530 1437 dbSNP
rs563406419 1440 dbSNP
rs1399465633 1441 dbSNP
rs748773297 1448 dbSNP
rs1000188942 1449 dbSNP
rs1357965869 1449 dbSNP
rs1217168273 1471 dbSNP
rs1295394382 1474 dbSNP
rs1407175112 1478 dbSNP
rs904545728 1482 dbSNP
rs1254291747 1486 dbSNP
rs977336642 1488 dbSNP
rs946245820 1489 dbSNP
rs965798914 1498 dbSNP
rs1019111455 1502 dbSNP
rs942857230 1503 dbSNP
rs1007192454 1521 dbSNP
rs953082549 1522 dbSNP
rs549700567 1523 dbSNP
rs1428693897 1524 dbSNP
rs1172127673 1536 dbSNP
rs777164580 1537 dbSNP
rs910958923 1541 dbSNP
rs1032873412 1543 dbSNP
rs984300115 1544 dbSNP
rs1313017339 1550 dbSNP
rs1000098187 1560 dbSNP
rs775438887 1569 dbSNP
rs769571550 1573 dbSNP
rs1288591356 1578 dbSNP
rs952408325 1582 dbSNP
rs1200494075 1583 dbSNP
rs1216734278 1585 dbSNP
rs1041529316 1590 dbSNP
rs1451729894 1593 dbSNP
rs192691215 1594 dbSNP
rs895867233 1596 dbSNP
rs1316605286 1597 dbSNP
rs1349895321 1607 dbSNP
rs1213587346 1610 dbSNP
rs544991756 1611 dbSNP
rs1486053975 1612 dbSNP
rs1188099886 1620 dbSNP
rs1250737469 1623 dbSNP
rs937320707 1626 dbSNP
rs1453491003 1628 dbSNP
rs972383038 1629 dbSNP
rs780784491 1630 dbSNP
rs540959067 1631 dbSNP
rs572745076 1634 dbSNP
rs572027018 1638 dbSNP
rs1316661113 1640 dbSNP
rs1346362478 1641 dbSNP
rs909904954 1645 dbSNP
rs1323210832 1651 dbSNP
rs1273345051 1655 dbSNP
rs1438836836 1665 dbSNP
rs1048662673 1669 dbSNP
rs1441936082 1673 dbSNP
rs930181352 1681 dbSNP
rs559295719 1689 dbSNP
rs1374807458 1703 dbSNP
rs1024868202 1708 dbSNP
rs1283446589 1710 dbSNP
rs1402379128 1718 dbSNP
rs918860232 1719 dbSNP
rs1217671032 1731 dbSNP
rs1271040000 1731 dbSNP
rs1012007170 1736 dbSNP
rs976906365 1738 dbSNP
rs1254285831 1739 dbSNP
rs1034421183 1741 dbSNP
rs1000727480 1745 dbSNP
rs1402962527 1747 dbSNP
rs186627373 1750 dbSNP
rs1394236419 1751 dbSNP
rs1462127002 1754 dbSNP
rs61746567 1775 dbSNP
rs1353025918 1782 dbSNP
rs1362774790 1783 dbSNP
rs557470569 1784 dbSNP
rs1373882701 1785 dbSNP
rs1458681949 1789 dbSNP
rs1291154954 1795 dbSNP
rs866286790 1804 dbSNP
rs754746349 1812 dbSNP
rs1010259454 1817 dbSNP
rs986308215 1820 dbSNP
rs901395602 1826 dbSNP
rs116110803 1830 dbSNP
rs1199795137 1832 dbSNP
rs1274653549 1840 dbSNP
rs1032612238 1843 dbSNP
rs575114569 1849 dbSNP
rs1276941266 1850 dbSNP
rs751422491 1852 dbSNP
rs553069726 1853 dbSNP
rs1279117360 1857 dbSNP
rs41267146 1859 dbSNP
rs1014083268 1860 dbSNP
rs556128532 1861 dbSNP
rs1034418044 1867 dbSNP
rs114704682 1869 dbSNP
rs1356373922 1877 dbSNP
rs888543895 1878 dbSNP
rs1310958278 1880 dbSNP
rs1357286984 1885 dbSNP
rs535928018 1886 dbSNP
rs1048401103 1888 dbSNP
rs1354810555 1890 dbSNP
rs1414753902 1893 dbSNP
rs538668162 1895 dbSNP
rs1383825414 1896 dbSNP
rs1336982070 1899 dbSNP
rs1213653042 1904 dbSNP
rs949070583 1907 dbSNP
rs897370445 1908 dbSNP
rs755151426 1919 dbSNP
rs944217338 1924 dbSNP
rs1208169016 1926 dbSNP
rs1441051210 1927 dbSNP
rs911409165 1928 dbSNP
rs567151004 1930 dbSNP
rs1371713236 1931 dbSNP
rs141775224 1942 dbSNP
rs1475177823 1943 dbSNP
rs959233417 1949 dbSNP
rs985660404 1950 dbSNP
rs1421962192 1958 dbSNP
rs1432917295 1969 dbSNP
rs1380341816 1971 dbSNP
rs1179888613 1975 dbSNP
rs1415343009 1976 dbSNP
rs79752339 1979 dbSNP
rs925708220 1985 dbSNP
rs1161525688 1987 dbSNP
rs1236170393 1993 dbSNP
rs556755848 1999 dbSNP
rs979291225 2000 dbSNP
rs1443315293 2002 dbSNP
rs751822875 2006 dbSNP
rs1231433674 2009 dbSNP
rs1278998076 2019 dbSNP
rs866485869 2020 dbSNP
rs1349157434 2035 dbSNP
rs753926769 2052 dbSNP
rs967052707 2060 dbSNP
rs1020199578 2064 dbSNP
rs1260033808 2065 dbSNP
rs1356001074 2067 dbSNP
rs993179702 2073 dbSNP
rs1310076472 2078 dbSNP
rs1244058334 2087 dbSNP
rs1452816763 2096 dbSNP
rs959884697 2098 dbSNP
rs1395797717 2100 dbSNP
rs1245232857 2101 dbSNP
rs1174217356 2104 dbSNP
rs1382764583 2117 dbSNP
rs867414879 2121 dbSNP
rs1399884433 2122 dbSNP
rs1318799758 2123 dbSNP
rs1376907732 2124 dbSNP
rs1285836516 2136 dbSNP
rs536811642 2143 dbSNP
rs1325614753 2144 dbSNP
rs1034567093 2162 dbSNP
rs1259462237 2163 dbSNP
rs1350657346 2167 dbSNP
rs1296004122 2171 dbSNP
rs1206024493 2180 dbSNP
rs61820868 2182 dbSNP
rs1270437387 2184 dbSNP
rs1001386894 2187 dbSNP
rs888492135 2198 dbSNP
rs1027078128 2201 dbSNP
rs1421132773 2204 dbSNP
rs1360672677 2209 dbSNP
rs1179821062 2214 dbSNP
rs1361988906 2216 dbSNP
rs1469565939 2220 dbSNP
rs994161514 2220 dbSNP
rs897186625 2231 dbSNP
rs756516923 2232 dbSNP
rs1459507359 2233 dbSNP
rs529822408 2240 dbSNP
rs1394821588 2246 dbSNP
rs1387993151 2252 dbSNP
rs1403031024 2259 dbSNP
rs1020379455 2260 dbSNP
rs1412303224 2267 dbSNP
rs1240422493 2287 dbSNP
rs1290556627 2289 dbSNP
rs571525141 2297 dbSNP
rs56060621 2298 dbSNP
rs1019873390 2302 dbSNP
rs1049846868 2311 dbSNP
rs75382178 2318 dbSNP
rs146976586 2319 dbSNP
rs1418380373 2326 dbSNP
rs978523079 2331 dbSNP
rs1414141487 2338 dbSNP
rs945716168 2340 dbSNP
rs896870694 2343 dbSNP
rs1036771586 2344 dbSNP
rs912915904 2345 dbSNP
rs992517558 2346 dbSNP
rs1295900330 2363 dbSNP
rs767835846 2367 dbSNP
rs1034272108 2373 dbSNP
rs1395188603 2378 dbSNP
rs979895924 2385 dbSNP
rs1391507756 2387 dbSNP
rs866341553 2390 dbSNP
rs949039446 2392 dbSNP
rs917621925 2410 dbSNP
rs545871927 2415 dbSNP
rs952556711 2418 dbSNP
rs1228783828 2421 dbSNP
rs1225547593 2425 dbSNP
rs1361094920 2425 dbSNP
rs1276051239 2427 dbSNP
rs1401554840 2428 dbSNP
rs937886045 2430 dbSNP
rs1302100493 2438 dbSNP
rs6425397 2442 dbSNP
rs994277276 2447 dbSNP
rs1186891285 2448 dbSNP
rs961497938 2454 dbSNP
rs1020010113 2455 dbSNP
rs1167846256 2461 dbSNP
rs1372196124 2468 dbSNP
rs1406458645 2468 dbSNP
rs1423428001 2470 dbSNP
rs979645217 2472 dbSNP
rs1008232103 2473 dbSNP
rs759830127 2474 dbSNP
rs890002381 2479 dbSNP
rs1313816104 2484 dbSNP
rs1020360628 2485 dbSNP
rs563610819 2492 dbSNP
rs1478971028 2497 dbSNP
rs543930955 2498 dbSNP
rs1295093315 2511 dbSNP
rs965361082 2514 dbSNP
rs1000987222 2516 dbSNP
rs1230690244 2522 dbSNP
rs1264193970 2527 dbSNP
rs1278287872 2530 dbSNP
rs1345586298 2535 dbSNP
rs575003677 2550 dbSNP
rs1006897821 2555 dbSNP
rs1484101645 2562 dbSNP
rs1487568271 2564 dbSNP
rs1260608006 2567 dbSNP
rs879926340 2568 dbSNP
rs1222288882 2571 dbSNP
rs1317235196 2581 dbSNP
rs1392748168 2584 dbSNP
rs1042777097 2587 dbSNP
rs565920996 2588 dbSNP
rs374448431 2590 dbSNP
rs41267144 2594 dbSNP
rs541652831 2598 dbSNP
rs1036738596 2599 dbSNP
rs374272632 2599 dbSNP
rs748861799 2599 dbSNP
rs949172524 2599 dbSNP
rs1410333816 2601 dbSNP
rs896242923 2607 dbSNP
rs1054695603 2617 dbSNP
rs1279228121 2618 dbSNP
rs1057161215 2635 dbSNP
rs201851487 2650 dbSNP
rs1213308455 2652 dbSNP
rs762473534 2659 dbSNP
rs927186270 2660 dbSNP
rs1217086652 2661 dbSNP
rs1192160864 2664 dbSNP
rs1210242491 2665 dbSNP
rs1250794373 2666 dbSNP
rs1369192950 2668 dbSNP
rs1293594695 2674 dbSNP
rs1440763335 2676 dbSNP
rs980055101 2678 dbSNP
rs572766655 2685 dbSNP
rs1417855872 2687 dbSNP
rs1158758963 2689 dbSNP
rs919730121 2691 dbSNP
rs1389884074 2692 dbSNP
rs1459195343 2695 dbSNP
rs1324113701 2696 dbSNP
rs1394102833 2701 dbSNP
rs1329842310 2703 dbSNP
rs972580022 2704 dbSNP
rs1441728841 2710 dbSNP
rs774807715 2711 dbSNP
rs913768604 2724 dbSNP
rs559248265 2727 dbSNP
rs1305974042 2734 dbSNP
rs1329563240 2737 dbSNP
rs1210410465 2744 dbSNP
rs975920060 2746 dbSNP
rs1221571957 2758 dbSNP
rs1247959208 2760 dbSNP
rs965416438 2762 dbSNP
rs1175701097 2763 dbSNP
rs1413412015 2764 dbSNP
rs912671452 2790 dbSNP
rs1019704931 2791 dbSNP
rs985838025 2794 dbSNP
rs769775933 2804 dbSNP
rs1325553947 2811 dbSNP
rs954101470 2812 dbSNP
rs1441617665 2815 dbSNP
rs1307312337 2818 dbSNP
rs1027631551 2819 dbSNP
rs995812978 2820 dbSNP
rs1457341306 2824 dbSNP
rs1008638621 2826 dbSNP
rs1333624927 2830 dbSNP
rs1228553640 2831 dbSNP
rs1291633822 2835 dbSNP
rs1305237923 2837 dbSNP
rs1203282802 2840 dbSNP
rs759459487 2841 dbSNP
rs207460684 2846 dbSNP
rs1458079445 2851 dbSNP
rs1255192469 2852 dbSNP
rs1013724954 2855 dbSNP
rs1473224616 2858 dbSNP
rs896211716 2859 dbSNP
rs1165188026 2861 dbSNP
rs1028514962 2863 dbSNP
rs1313606149 2869 dbSNP
rs1001103351 2873 dbSNP
rs776621033 2878 dbSNP
rs1054909569 2882 dbSNP
rs538231737 2888 dbSNP
rs748762150 2890 dbSNP
rs1373978873 2898 dbSNP
rs1448549043 2899 dbSNP
rs1285581785 2907 dbSNP
rs1042508114 2917 dbSNP
rs1213413052 2928 dbSNP
rs1274755469 2932 dbSNP
rs1344880885 2939 dbSNP
rs1009738558 2941 dbSNP
rs1401552699 2951 dbSNP
rs1280285277 2954 dbSNP
rs1443328925 2959 dbSNP
rs1240567467 2962 dbSNP
rs1044026395 2964 dbSNP
rs945276752 2971 dbSNP
rs891503522 2974 dbSNP
rs1431505465 2979 dbSNP
rs1056916039 2981 dbSNP
rs192825378 2983 dbSNP
rs555900437 2985 dbSNP
rs944537003 2989 dbSNP
rs1324265299 2991 dbSNP
rs1439215603 2993 dbSNP
rs565969491 3004 dbSNP
rs535916834 3005 dbSNP
rs985586963 3028 dbSNP
rs567026539 3032 dbSNP
rs1440226530 3034 dbSNP
rs954183929 3041 dbSNP
rs1202474340 3050 dbSNP
rs1198523010 3052 dbSNP
rs1446588047 3055 dbSNP
rs1209629516 3062 dbSNP
rs1484091716 3062 dbSNP
rs919972455 3066 dbSNP
rs1256273283 3072 dbSNP
rs1193161788 3084 dbSNP
rs1376933146 3087 dbSNP
rs1044324540 3089 dbSNP
rs974489026 3091 dbSNP
rs1382554715 3092 dbSNP
rs188073786 3095 dbSNP
rs770902902 3110 dbSNP
rs1336874529 3116 dbSNP
rs1312583046 3123 dbSNP
rs919844680 3148 dbSNP
rs527524939 3152 dbSNP
rs1332122701 3158 dbSNP
rs1381769011 3159 dbSNP
rs1236095786 3168 dbSNP
rs571450471 3175 dbSNP
rs1328870824 3186 dbSNP
rs1229460055 3189 dbSNP
rs961270287 3201 dbSNP
rs1467314772 3211 dbSNP
rs1303684148 3216 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000361833.2 | 3UTR | UCAAGCAUUCCUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000361833.2 | 3UTR | UCAAGCAUUCCUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE32688 Pancreatic cancer 0.374 1.7e-2 0.185 1.6e-1 32 Click to see details
GSE27834 Pluripotent stem cells 0.192 2.4e-1 0.147 2.9e-1 16 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.122 2.8e-1 0.029 4.5e-1 25 Click to see details
GSE21849 B cell lymphoma -0.095 3.1e-1 0.151 2.2e-1 29 Click to see details
GSE17306 Multiple myeloma -0.013 4.6e-1 0.311 1.5e-2 49 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
85 hsa-miR-516b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT077049 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT155261 IFNAR2 interferon alpha and beta receptor subunit 2 2 4
MIRT446119 ASTN1 astrotactin 1 2 2
MIRT447355 STOM stomatin 2 2
MIRT469329 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT470201 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT475944 GXYLT1 glucoside xylosyltransferase 1 2 4
MIRT498268 KIAA1644 KIAA1644 2 2
MIRT501725 OVOL1 ovo like transcriptional repressor 1 2 2
MIRT522860 KIAA1551 KIAA1551 2 2
MIRT527900 B3GALT5 beta-1,3-galactosyltransferase 5 2 4
MIRT528557 DNAAF3 dynein axonemal assembly factor 3 2 2
MIRT531250 PDF peptide deformylase, mitochondrial 2 2
MIRT534410 SENP1 SUMO1/sentrin specific peptidase 1 2 2
MIRT544656 MED19 mediator complex subunit 19 2 2
MIRT550681 YARS tyrosyl-tRNA synthetase 2 2
MIRT557208 HNRNPF heterogeneous nuclear ribonucleoprotein F 2 4
MIRT611532 DDB1 damage specific DNA binding protein 1 2 2
MIRT612087 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT616535 PARD6B par-6 family cell polarity regulator beta 2 4
MIRT616738 DCTN5 dynactin subunit 5 2 2
MIRT616754 SVOP SV2 related protein 2 4
MIRT617380 FAM227A family with sequence similarity 227 member A 2 2
MIRT617624 RAB3IP RAB3A interacting protein 2 2
MIRT620778 MT1A metallothionein 1A 2 2
MIRT623172 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT626034 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT627376 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT630533 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT631686 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT633896 FGF10 fibroblast growth factor 10 2 2
MIRT635933 PLA2G12A phospholipase A2 group XIIA 2 2
MIRT636275 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636285 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT636502 GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 2 2
MIRT638037 SHPK sedoheptulokinase 2 2
MIRT639162 LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2 2
MIRT639571 GORASP1 golgi reassembly stacking protein 1 2 2
MIRT641248 CENPN centromere protein N 2 2
MIRT643650 MYOCD myocardin 2 2
MIRT645490 TRIM63 tripartite motif containing 63 2 2
MIRT648016 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT648102 LRRFIP1 LRR binding FLII interacting protein 1 2 2
MIRT648729 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT650177 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT652787 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT653248 SORD sorbitol dehydrogenase 2 2
MIRT654859 PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F 2 2
MIRT655533 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT656390 MCU mitochondrial calcium uniporter 2 2
MIRT656881 KIF1C kinesin family member 1C 2 2
MIRT657083 JMY junction mediating and regulatory protein, p53 cofactor 2 2
MIRT657629 GPX8 glutathione peroxidase 8 (putative) 2 2
MIRT658295 FAM83F family with sequence similarity 83 member F 2 2
MIRT659432 COL1A1 collagen type I alpha 1 chain 2 2
MIRT659791 CBLB Cbl proto-oncogene B 2 2
MIRT660153 BRCC3 BRCA1/BRCA2-containing complex subunit 3 2 2
MIRT660490 ARRDC3 arrestin domain containing 3 2 2
MIRT660503 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT666356 SIKE1 suppressor of IKBKE 1 2 2
MIRT677774 FKTN fukutin 2 2
MIRT688556 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT697415 ZFP91 ZFP91 zinc finger protein 2 2
MIRT709468 KRTAP19-1 keratin associated protein 19-1 2 2
MIRT711154 WDR82P1 WD repeat domain 82 pseudogene 1 2 2
MIRT711467 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT712515 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT712661 PCTP phosphatidylcholine transfer protein 2 2
MIRT713304 TYRP1 tyrosinase related protein 1 2 2
MIRT714597 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT716603 MPPED1 metallophosphoesterase domain containing 1 2 2
MIRT717537 PYGO2 pygopus family PHD finger 2 2 2
MIRT718058 CYP3A5 cytochrome P450 family 3 subfamily A member 5 2 2
MIRT718539 PIGQ phosphatidylinositol glycan anchor biosynthesis class Q 2 2
MIRT719768 ZNF236 zinc finger protein 236 2 2
MIRT720162 PNPO pyridoxamine 5'-phosphate oxidase 2 2
MIRT720360 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT721182 HOPX HOP homeobox 2 2
MIRT721278 RAD54L2 RAD54 like 2 2 2
MIRT721357 ENTHD1 ENTH domain containing 1 2 2
MIRT721504 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT721918 LINGO2 leucine rich repeat and Ig domain containing 2 2 2
MIRT722278 LURAP1 leucine rich adaptor protein 1 2 2
MIRT722789 FUT4 fucosyltransferase 4 2 2
MIRT724390 ABAT 4-aminobutyrate aminotransferase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-516b Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-516b Bromocriptine approved 31101 Microarray Prolactinoma 22366961 2012 up-regulated
miR-516b Bromocriptine approved 31101 Quantitative real-time PCR Prolactinoma 22366961 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-516b-3p Paclitaxel 36314 NSC125973 approved sensitive High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-516b-3p Ribavirin+Pegylated IFNa-2b sensitive tissue (chronic hepatitis C)
hsa-miR-516b-3p Testosterone+Exemestane sensitive cell line (MCF-7)
hsa-miR-516b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-516b-3p Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)

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