miRTarBase - #MIRT446627


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pre-miRNA Information
pre-miRNA hsa-mir-124-1   
Genomic Coordinates chr8: 9903388 - 9903472
Description Homo sapiens miR-124-1 stem-loop
Comment miR-124 was first identified by cloning studies in mouse . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-124-2   
Genomic Coordinates chr8: 64379149 - 64379257
Description Homo sapiens miR-124-2 stem-loop
Comment miR-124 was first identified by cloning studies in mouse . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-124-3   
Genomic Coordinates chr20: 63178500 - 63178586
Description Homo sapiens miR-124-3 stem-loop
Comment miR-124 was first identified by cloning studies in mouse . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-124-5p
Sequence 14| CGUGUUCACAGCGGACCUUGAU |35
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 8 8 + 64379180 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1280076135 1 dbSNP
rs775858016 4 dbSNP
rs760972715 7 dbSNP
rs1334649236 11 dbSNP
rs1160219511 12 dbSNP
rs764591061 12 dbSNP
rs1261326747 13 dbSNP
rs1344491363 20 dbSNP
rs1340798465 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B28CWB miR-124 Safety Biomarker (SAF); Monitoring Biomarker (MOI) Clinical/Experimental Data Expression Increase Plasma Polymerase chain reaction
B28CWB miR-124 Safety Biomarker (SAF); Monitoring Biomarker (MOI) Clinical/Experimental Data Expression Decrease Neuron Reverse transcription-polymerase chain reaction
B28CWB miR-124 Safety Biomarker (SAF); Monitoring Biomarker (MOI) Clinical/Experimental Data Expression Decrease Peripheral blood mononuclear cell Reverse transcription-polymerase chain reaction
Gene Information
Gene Symbol SDC3   
Synonyms SDCN, SYND3
Description syndecan 3
Transcript NM_014654   
Expression
Putative miRNA Targets on SDC3
3'UTR of SDC3
(miRNA target sites are highlighted)		 
>SDC3|NM_014654|3'UTR
   1 TGGAGCCACAGTGCCTCCCTGCAGCCTCAACACCACCCTGCTGTCCAGTCCCCAGCCTGGCCCCACCAGCCCAAGCCTGG
  81 GACTGGGCCTGGAACCTGGCCCCAGTTCTTCTCTGCCCTCTCTCCCAAGGTCTGCCCAGGCTGCCAGCCTCACACAGATC
 161 TTCCCCGAGGAAGAGGGGCTGCTGCCATCTGCCCCAGACTGTGCCCTTACGAGCTCATCTCTTGTTCCCCTCATCCCTGC
 241 CACCAGTCTGGGGCTTCAGGACCTCATGTCAGATGGATGGGAGGAAGAAAGCTCCTGATTGGCTGGTGGTGGAAGAAAGG
 321 GTGGGGCTTGAGATGAGCCTGAGCCCTGACTTGGCACCCACAGTGCTCACTGAGATCTCCTTTTTGGGGCAGAGAGGCAC
 401 TCAGGCTGGTTTCCAGGACAAACATTTGGTAAACACAGCCCTTGAAATCATCTAGACACTGCAACCTCTTGCTCGTATCC
 481 CAGGGCCTCTCTCTAGCTGGGTGAGAGGGTGTCCCTTGTCACCAGCCTGTTTTGTCCTGGTCTCTCTGGGGTTGTTGAAT
 561 CTCTCCTCTTGCCTGCCAAGTACACATGTACCCAGACTTCATTTCTTTCTGCATCTTCCCCCAAGAAACAGCTTCCTGAG
 641 GGTGCTGGGGCAGCCACTGGTGAGGAGGGGCTGCTCTGATGTCCCTCCTATGAGGGGACTCTGCACAGACACCATTGCCC
 721 ACACTATCACCATATTTTCACTCAGTCACACACAAGACAAAAGCATGCAATGACAAAACCATACGCAATCCTGACCGCCC
 801 AGCCAATCAAGACATATCACAGAACACACGCGTCCTTCCAAGAATGTTTATCCTCATGCATCACTTACACACCCCCAGAC
 881 ACGTACTGCAATGCAAGTCACTAGTCATGGTCACATGACAGTGACAGTGTGGCCTCCTCCTACCCCAAATACACCCACAC
 961 TCTGGCACCACACACATTGTCTCCAGCTTTCAGGCTTACTGGGGAGGGTGGAATCGAGCCAGAACAATCAGCCCATATTG
1041 GGTCCCCCTAAGTTGCCCCGTCATACTCAGTCCCATGCCATGGTGCCCACACCAACCATGCAGCCGCCAACCCCAGCCAG
1121 TGTCAGACACAATCCCATGTGGATGCACAGTCTCACTCCACATGACCTGCTCTCAATGCTGGAGGGAAACAGGCAGGCCC
1201 TTGCCTTTCTCGGAAAAAGTGTGGGGCCACAGCCCTTTTAGGGCATTGCATGCAGGTGGGCCTGGCTTCACCCCTACCTG
1281 CTTCCTCCCCACCGCAGCTGGCAGAGGGGGAGGTTTGGGGCCAGACCCCCACTAGCTGGGAGCCTGGGGGCTCCTCTAAG
1361 GCTGAGGAAGGAAATTTGGCCCCAGGTTGTTGGGGGGTCTTGGGTCTCCCAGGACGGAAGGCCCAGGGCAGGGAGGGGGC
1441 ATGTGGTTGGGCTCCTTTATCTCCCTGTGTCCCCTTCCTGCTTTGAGCTAGGGGGCTGACTCTGCCTCCCAGGACACAAG
1521 TCTCCAAAGTGCCTGTGAGGGCGGGCCCTCCGCACCCTCTGCCCTCTGCCTGGCAGGCCAACCTCAGCCCACCTGCCCAG
1601 AGGCCCTCCCTGTGGACACCCCCTCACCTATTTGGCCAAACAATTCTGGCTGCAGCTTCAGGGGCCATGGCTGGAAGCAG
1681 CCCCTGCAGATCCCTCAGGCCCCGAGGTCAGGGTTTGAGGGATGAGACCAGGTGATAGTGGGGGAGGGGTTACTTCCTTT
1761 GTTACCTAGCAAGTAGGGCTATTTCCATCGGTATTTTAAATGTGGGGTCACAGATCTTTTGGGGAGGGTGTGCTTGGCAG
1841 GGGGCCTCTTGGAGCCAAAGGGATGTGGTGTGAGTTGCGATTGGCTGGCACTCACACCCCCACCCCTCACCCACATCCCA
1921 GATTCAAGTCAGGAAGGCAGGTTTTATTTCAGGGCCCTTTTCAAGATGCCCTGGCAGCAGATTTCTGCAGGATGAGGGGT
2001 AGCGGTGTGTAGGCAGTGAGGGGGAGGTTCCAGGGGCTGTCCCACAGCCTGTCTTTTCCAGGCTGGGCTCCATCTTCCAG
2081 TCCCAAAACCCTCCTTCACAGGGCCCAGAGGCTTGTGAGGAAGCCAGGTGGACCCAGCCTTAGAAGAGTGGGCATGGGGG
2161 GCCCCTGATATCTGGAGGGGGCGGGTTGGCCTCAGTCATCTTTGGAGCAGAAGGGCTGGGTCCTGGGGCCACAGACCACA
2241 AGGCTCAGCCTCCCTACCCTGCTCCCTGGGGTGCTGCTGTCTTGGAGAGCACAGCTCTGGTGAGACGGCCTGGGCAGGCC
2321 GAGGCTGAGAAACCAGGGAGGATAGAGGAGAAAAGGGCTTGGGCCCCCAGCCCCAGAAGATGCTGGACCCCAGGTGGGAG
2401 ACCCAACAGTGGGTGCAGTTTCTCAGTAGGGCTGGAGCCAATGGTGGGGGTGGCCCCGGCAGGCCTGGCTCCTCACATCC
2481 CAGGGGTTGGCTTCTGATTTGGGGCTTGGGCTCCAGGCACTGGCTTCTCTTCTCTGTGTCCTTAGCATTTGAGAGAAGAG
2561 GCCAGGGGCCTTGTTCATGGATCCCTGGACCCAAGGCAGATGTCCAGGCTTTATCCTCCTGAGGATGAGGAGTCTGACCA
2641 GCCCAAATCTGCCCTGGCCGGCCTGACCGGGGCAAGGCAGTCCAAGAGAGTTCAGTGAGGACCAGCTAGGCTCTCCCAGG
2721 TGCAATGTGGGTGCAGGGCCCTCATGTCCCCCTACCCCTGCCTGTGATGGAGTGTTCTGAGGGGCTTTGGCATTTGCTGG
2801 AAGCACAGGGAGTTCCAAATGAGAGGGAGCTTCTGTGGCTTGAGAGCCTCTGGGGCCTTGGCTGCCAGAGCACGAGGCAG
2881 GCCAGGACCTGGAGAGCCCAGACCCTGTCTCCAGGAGGCCAGGAGGCCAGATGGGGGCCTTGCCTGAAAGACTGGTCCCC
2961 TTGATCGCTGGAGGCATGTGGGTGGCAACCAGGGCTGGGCAGGGCTTAGGGTGTGTGGGCCAAACCCCCCTGGGGTTGGC
3041 AAAGCCGCCTGTCAGGCCTCCTGGTGGGGGCCCCTGGACACAGGGAGCAGACCCTCTGCCTCATGGGGTAGGAGTGGCTG
3121 CCTCCTGTGTTCTCTGGATTTCTTCTCCCAACAACTACAACCCTGGACTTGCCTCCCCAGGCCTCTTGCCTGTAAATAGA
3201 AGCCCGCAAACTGTACAGATTTACAGAGGCATCGAGACTGGGCCCTGGGAGTTGCCATCTGAGAGCCGATGGCCCCAGCA
3281 TCCCCCAGGTGCCTGCCTGGCACCACAGTGACCCTGGCCTCAGCGTGGCAAATGCATGTAAATATTTTTCGTAGGCAGCG
3361 TGGCTCCAGAGAGCCCCCTGAAGACAGTGTCCCTCCCTCCTGTGAGTCCTTTCTCCTGTACAGAACCTGCCTGGGGTGGG
3441 TGGGGGTCTGCCATTCCCTCCCCCAGGCCTTCCCTGCCCCTTCTCTCCCCTGTAACCTGTTTATTAACCATACCTGTCCT
3521 GAGTTCATGGCCAAAACCTTAAATAAGAAAAACAAAAGAAAAAGACAGTGGAAAAAAGAGACCAAGGCGCCTGCCCCACT
3601 GCGGGTACTCTCCTGTTCCAGCCTTGTGAAGGAACTGGTTTTGTTTTTGTTTTTTTTTTTTTTTTTTTTTTTTTGTTTGT
3681 TTGTTTTTTTAACACTTCCTGTGCTGTGCCCATTTATAAGAGGAAATAAAATTAAGCTGAAATGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaGU-UCC---AGGCGACACUUGUGc 5'
            || |||   ||| |||||:|||| 
Target 5' ccCAGAGGCCCTCC-CTGTGGACACc 3'
 1596 - 1620 151.00 -20.30
2 
miRNA  3' uaGUUCCAGGCGACACUUGUGc 5'
            :::|| || |  ||:|||| 
Target 5' ggTGGGGGCCCC--TGGACACa 3'
 3063 - 3082 136.00 -12.90
3 
miRNA  3' uaguuccaggcgacaCUUGUGc 5'
                         |||||| 
Target 5' tcaagacatatcacaGAACACa 3'
 807 - 828 120.00 -7.71
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN19613757 1 COSMIC
COSN30449792 3 COSMIC
COSN30150541 13 COSMIC
COSN30172084 28 COSMIC
COSN30526515 52 COSMIC
COSN13537640 105 COSMIC
COSN31550025 117 COSMIC
COSN31536316 118 COSMIC
COSN30184378 143 COSMIC
COSN30497735 156 COSMIC
COSN6453338 166 COSMIC
COSN6453337 273 COSMIC
COSN15227279 362 COSMIC
COSN8456585 406 COSMIC
COSN1443162 504 COSMIC
COSN7990168 883 COSMIC
COSN8972069 976 COSMIC
COSN29374029 1503 COSMIC
COSN16830011 1581 COSMIC
COSN20698664 1790 COSMIC
COSN17279815 1808 COSMIC
COSN10047197 2005 COSMIC
COSN1102846 2320 COSMIC
COSN26848830 2379 COSMIC
COSN18723690 2385 COSMIC
COSN32057542 2449 COSMIC
COSN10047196 3344 COSMIC
COSN6033659 3360 COSMIC
COSN20094638 3653 COSMIC
COSN7216913 3661 COSMIC
COSN8456584 3667 COSMIC
COSN18998620 3669 COSMIC
COSN27880159 3670 COSMIC
COSN15565966 3671 COSMIC
COSN20094632 3684 COSMIC
COSN20094637 3684 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs3766284 1 dbSNP
rs759986082 3 dbSNP
rs1180925064 10 dbSNP
rs774939187 12 dbSNP
rs1271436957 15 dbSNP
rs1200572887 24 dbSNP
rs1451433475 25 dbSNP
rs376005184 31 dbSNP
rs762328815 33 dbSNP
rs1351417109 36 dbSNP
rs914798871 38 dbSNP
rs969076362 43 dbSNP
rs573574224 63 dbSNP
rs145139015 77 dbSNP
rs937510347 78 dbSNP
rs1273521189 80 dbSNP
rs960667956 84 dbSNP
rs1478359283 87 dbSNP
rs1270286761 95 dbSNP
rs1015240874 98 dbSNP
rs747930134 102 dbSNP
rs1329892816 105 dbSNP
rs1325891598 106 dbSNP
rs1405991440 113 dbSNP
rs776602606 124 dbSNP
rs981501411 125 dbSNP
rs1431689092 130 dbSNP
rs1420238653 134 dbSNP
rs1172070497 148 dbSNP
rs887102512 148 dbSNP
rs1244932874 152 dbSNP
rs775810063 157 dbSNP
rs951429372 158 dbSNP
rs3766285 166 dbSNP
rs35807336 167 dbSNP
rs962978874 167 dbSNP
rs1343864584 171 dbSNP
rs1273053514 174 dbSNP
rs1218155323 178 dbSNP
rs1018173104 183 dbSNP
rs1218355696 184 dbSNP
rs1224499946 193 dbSNP
rs578010255 197 dbSNP
rs995596233 203 dbSNP
rs890956049 209 dbSNP
rs74331654 210 dbSNP
rs1039888254 211 dbSNP
rs746510668 217 dbSNP
rs1422968721 227 dbSNP
rs944191616 227 dbSNP
rs891401821 228 dbSNP
rs1199389420 232 dbSNP
rs76178805 235 dbSNP
rs935033158 239 dbSNP
rs186477099 241 dbSNP
rs946388676 245 dbSNP
rs1166068453 271 dbSNP
rs12757735 273 dbSNP
rs1056045432 275 dbSNP
rs184029189 280 dbSNP
rs149951167 283 dbSNP
rs1338931379 292 dbSNP
rs1224596194 299 dbSNP
rs947824743 301 dbSNP
rs928812313 305 dbSNP
rs981553679 306 dbSNP
rs1230645711 307 dbSNP
rs1401485316 307 dbSNP
rs3820088 311 dbSNP
rs1415241434 321 dbSNP
rs1283863835 324 dbSNP
rs117399193 327 dbSNP
rs974504040 333 dbSNP
rs756469678 343 dbSNP
rs960802594 356 dbSNP
rs1014880265 369 dbSNP
rs983357909 374 dbSNP
rs1337478833 375 dbSNP
rs1168582852 383 dbSNP
rs1465603557 384 dbSNP
rs191858700 386 dbSNP
rs1156661276 390 dbSNP
rs1420700736 392 dbSNP
rs1018641649 398 dbSNP
rs1188686713 399 dbSNP
rs1471612284 409 dbSNP
rs1471974005 423 dbSNP
rs1244371461 429 dbSNP
rs1203786872 435 dbSNP
rs1464801933 441 dbSNP
rs370927629 442 dbSNP
rs1266833772 443 dbSNP
rs1237254813 458 dbSNP
rs1186489208 474 dbSNP
rs1317959515 475 dbSNP
rs1027007798 484 dbSNP
rs1289633148 490 dbSNP
rs985381987 491 dbSNP
rs1381660806 503 dbSNP
rs1315765224 505 dbSNP
rs995480085 506 dbSNP
rs1264515091 520 dbSNP
rs1364335716 526 dbSNP
rs899945540 527 dbSNP
rs1196158330 531 dbSNP
rs527890315 536 dbSNP
rs1273543771 544 dbSNP
rs1345502540 547 dbSNP
rs1216124274 551 dbSNP
rs1403200428 559 dbSNP
rs1029518861 563 dbSNP
rs1008436610 571 dbSNP
rs1448391693 574 dbSNP
rs902287859 576 dbSNP
rs891281431 580 dbSNP
rs1022025017 581 dbSNP
rs1011025273 586 dbSNP
rs1219856149 588 dbSNP
rs1453702660 589 dbSNP
rs1385234021 592 dbSNP
rs894821247 601 dbSNP
rs1054681038 605 dbSNP
rs1052519813 611 dbSNP
rs1355626496 618 dbSNP
rs907437012 619 dbSNP
rs74665073 624 dbSNP
rs1299929478 628 dbSNP
rs1404096355 631 dbSNP
rs1362608760 636 dbSNP
rs904089175 641 dbSNP
rs1434090236 650 dbSNP
rs930127720 657 dbSNP
rs543901073 659 dbSNP
rs1444891300 665 dbSNP
rs1038446461 669 dbSNP
rs542705400 677 dbSNP
rs1176247794 678 dbSNP
rs1429579240 681 dbSNP
rs1267329690 690 dbSNP
rs947696725 693 dbSNP
rs1189814550 694 dbSNP
rs1490963262 697 dbSNP
rs941408297 705 dbSNP
rs916354769 715 dbSNP
rs1204624678 718 dbSNP
rs1482197477 723 dbSNP
rs187009229 728 dbSNP
rs992312359 731 dbSNP
rs1228270187 733 dbSNP
rs578229465 744 dbSNP
rs879216679 751 dbSNP
rs1300554305 755 dbSNP
rs139056828 763 dbSNP
rs112214574 784 dbSNP
rs922498657 785 dbSNP
rs1246372187 789 dbSNP
rs977941762 793 dbSNP
rs966564122 796 dbSNP
rs183558286 797 dbSNP
rs1462089010 808 dbSNP
rs1027561797 812 dbSNP
rs974094752 814 dbSNP
rs550380468 815 dbSNP
rs766504771 829 dbSNP
rs193080406 830 dbSNP
rs541375255 831 dbSNP
rs1008736833 832 dbSNP
rs1349763759 837 dbSNP
rs1196420744 850 dbSNP
rs1483005041 858 dbSNP
rs955444625 860 dbSNP
rs1031147575 872 dbSNP
rs1304165819 877 dbSNP
rs541718930 882 dbSNP
rs1045960270 883 dbSNP
rs1156519873 886 dbSNP
rs994777251 889 dbSNP
rs1227612967 890 dbSNP
rs1333593629 901 dbSNP
rs904141934 903 dbSNP
rs1391453869 911 dbSNP
rs1400809183 917 dbSNP
rs572200702 922 dbSNP
rs555298652 926 dbSNP
rs1178409124 927 dbSNP
rs1011952127 940 dbSNP
rs894792828 941 dbSNP
rs1038903559 942 dbSNP
rs1222953334 944 dbSNP
rs1490762043 946 dbSNP
rs1365753607 950 dbSNP
rs572637456 956 dbSNP
rs1056097524 958 dbSNP
rs765421457 960 dbSNP
rs939118061 962 dbSNP
rs1185525071 966 dbSNP
rs907598330 967 dbSNP
rs371025324 969 dbSNP
rs1309272780 974 dbSNP
rs920498492 974 dbSNP
rs1217512266 975 dbSNP
rs1047626898 979 dbSNP
rs1348354556 983 dbSNP
rs1262287894 987 dbSNP
rs535927389 999 dbSNP
rs1284423277 1001 dbSNP
rs576476525 1007 dbSNP
rs1239237977 1014 dbSNP
rs556111435 1015 dbSNP
rs369776204 1020 dbSNP
rs555385364 1025 dbSNP
rs1452662790 1034 dbSNP
rs1384140663 1040 dbSNP
rs920550923 1045 dbSNP
rs1399307616 1046 dbSNP
rs975058325 1057 dbSNP
rs1159540978 1059 dbSNP
rs369541320 1060 dbSNP
rs915099859 1064 dbSNP
rs539452236 1072 dbSNP
rs911216627 1081 dbSNP
rs986794289 1082 dbSNP
rs1481361244 1083 dbSNP
rs1445387563 1085 dbSNP
rs1243667288 1088 dbSNP
rs570772632 1096 dbSNP
rs188844113 1098 dbSNP
rs534273285 1105 dbSNP
rs2488238 1106 dbSNP
rs968182413 1111 dbSNP
rs1022536250 1112 dbSNP
rs1003201978 1113 dbSNP
rs1289192968 1128 dbSNP
rs1247523993 1136 dbSNP
rs548511093 1146 dbSNP
rs1012919609 1152 dbSNP
rs895379075 1161 dbSNP
rs1262645655 1162 dbSNP
rs1056547825 1180 dbSNP
rs1208129338 1184 dbSNP
rs776350996 1186 dbSNP
rs528952840 1190 dbSNP
rs183864058 1194 dbSNP
rs1319364049 1199 dbSNP
rs1386602418 1200 dbSNP
rs1263828923 1207 dbSNP
rs575763754 1211 dbSNP
rs75651429 1212 dbSNP
rs1425545700 1220 dbSNP
rs1166256916 1226 dbSNP
rs564117223 1232 dbSNP
rs1277989199 1233 dbSNP
rs1006118771 1235 dbSNP
rs1193597169 1238 dbSNP
rs1450889895 1239 dbSNP
rs930497259 1245 dbSNP
rs920435986 1246 dbSNP
rs1490412912 1250 dbSNP
rs541309990 1251 dbSNP
rs1212340916 1252 dbSNP
rs1342047845 1254 dbSNP
rs1038828017 1265 dbSNP
rs1271351087 1275 dbSNP
rs746884605 1280 dbSNP
rs943298208 1285 dbSNP
rs1362226488 1291 dbSNP
rs143292991 1293 dbSNP
rs1464216901 1294 dbSNP
rs1370216455 1307 dbSNP
rs1404802488 1312 dbSNP
rs1049835144 1313 dbSNP
rs934012294 1320 dbSNP
rs1176496946 1326 dbSNP
rs1398543347 1327 dbSNP
rs1168484422 1331 dbSNP
rs1470930392 1332 dbSNP
rs1480078165 1336 dbSNP
rs1421346552 1340 dbSNP
rs771530682 1355 dbSNP
rs561888787 1357 dbSNP
rs1250666228 1359 dbSNP
rs1201817046 1360 dbSNP
rs1428835281 1378 dbSNP
rs778604477 1379 dbSNP
rs541680962 1381 dbSNP
rs1461016226 1382 dbSNP
rs1285526366 1383 dbSNP
rs189880939 1386 dbSNP
rs1022420264 1389 dbSNP
rs1243875959 1390 dbSNP
rs556248541 1393 dbSNP
rs1316629348 1397 dbSNP
rs539100986 1398 dbSNP
rs1228627626 1403 dbSNP
rs1309688752 1406 dbSNP
rs1355131390 1413 dbSNP
rs959920554 1414 dbSNP
rs1035263216 1415 dbSNP
rs1003661259 1416 dbSNP
rs1381529298 1417 dbSNP
rs886099269 1420 dbSNP
rs1406772077 1424 dbSNP
rs1175056592 1425 dbSNP
rs115283413 1430 dbSNP
rs185470832 1432 dbSNP
rs748538058 1435 dbSNP
rs1039290889 1439 dbSNP
rs943202725 1441 dbSNP
rs1017584021 1446 dbSNP
rs1005755322 1451 dbSNP
rs866703329 1454 dbSNP
rs1398043804 1459 dbSNP
rs1204709332 1460 dbSNP
rs553779915 1470 dbSNP
rs534493079 1478 dbSNP
rs1225615344 1490 dbSNP
rs1028458691 1492 dbSNP
rs1374370143 1514 dbSNP
rs781633385 1530 dbSNP
rs1283624672 1539 dbSNP
rs568680437 1542 dbSNP
rs1380484924 1543 dbSNP
rs752059883 1544 dbSNP
rs780741225 1545 dbSNP
rs998291435 1547 dbSNP
rs923950228 1548 dbSNP
rs978022727 1551 dbSNP
rs139840753 1552 dbSNP
rs1162403258 1555 dbSNP
rs915317523 1557 dbSNP
rs945352361 1571 dbSNP
rs991421774 1571 dbSNP
rs959566128 1574 dbSNP
rs893764050 1580 dbSNP
rs1245499417 1581 dbSNP
rs1184691200 1585 dbSNP
rs28654360 1591 dbSNP
rs1386049756 1592 dbSNP
rs1485830996 1598 dbSNP
rs1185504222 1599 dbSNP
rs538062479 1619 dbSNP
rs982368931 1620 dbSNP
rs1317711537 1627 dbSNP
rs1291397874 1628 dbSNP
rs569509999 1631 dbSNP
rs1361605887 1632 dbSNP
rs376967949 1634 dbSNP
rs1481887195 1638 dbSNP
rs370146631 1640 dbSNP
rs1244472209 1643 dbSNP
rs1345418354 1648 dbSNP
rs1302213759 1649 dbSNP
rs1422378391 1655 dbSNP
rs1386492632 1662 dbSNP
rs918987593 1679 dbSNP
rs971778219 1681 dbSNP
rs963370146 1682 dbSNP
rs1188652519 1687 dbSNP
rs1315245868 1688 dbSNP
rs994475671 1692 dbSNP
rs751834804 1703 dbSNP
rs1374103975 1704 dbSNP
rs1017335737 1711 dbSNP
rs1490910070 1712 dbSNP
rs1327570328 1718 dbSNP
rs984785066 1727 dbSNP
rs1391946612 1732 dbSNP
rs1226844299 1734 dbSNP
rs954256612 1740 dbSNP
rs1216098834 1744 dbSNP
rs1398482172 1747 dbSNP
rs1362329305 1748 dbSNP
rs1291599859 1758 dbSNP
rs1423687985 1767 dbSNP
rs1402676602 1773 dbSNP
rs1028511212 1783 dbSNP
rs1165765184 1786 dbSNP
rs1461081120 1787 dbSNP
rs1353255825 1789 dbSNP
rs866642325 1790 dbSNP
rs1429633034 1796 dbSNP
rs965478005 1797 dbSNP
rs1021456545 1804 dbSNP
rs890286122 1805 dbSNP
rs3766286 1808 dbSNP
rs564054148 1810 dbSNP
rs1265808934 1814 dbSNP
rs1253166300 1816 dbSNP
rs547092223 1826 dbSNP
rs1042401084 1828 dbSNP
rs1262226027 1832 dbSNP
rs1490632412 1838 dbSNP
rs1294397167 1842 dbSNP
rs1221513118 1844 dbSNP
rs946702827 1860 dbSNP
rs1002095652 1869 dbSNP
rs1224305556 1871 dbSNP
rs1301612291 1878 dbSNP
rs1046243370 1879 dbSNP
rs1299412705 1889 dbSNP
rs1348076418 1897 dbSNP
rs949201557 1899 dbSNP
rs1174684695 1903 dbSNP
rs1226925375 1905 dbSNP
rs1471196998 1910 dbSNP
rs1239088531 1921 dbSNP
rs1430232143 1927 dbSNP
rs1181292495 1936 dbSNP
rs1417565540 1941 dbSNP
rs915353797 1972 dbSNP
rs1252713272 1976 dbSNP
rs919051551 1982 dbSNP
rs990913884 1996 dbSNP
rs1262477171 1998 dbSNP
rs114182890 2003 dbSNP
rs928156882 2004 dbSNP
rs908891354 2005 dbSNP
rs982253414 2012 dbSNP
rs1404239319 2014 dbSNP
rs561838517 2018 dbSNP
rs754096749 2020 dbSNP
rs1304694254 2021 dbSNP
rs776193235 2022 dbSNP
rs973087706 2041 dbSNP
rs1335392206 2043 dbSNP
rs963073632 2044 dbSNP
rs1017803235 2046 dbSNP
rs1407217409 2047 dbSNP
rs1384480106 2060 dbSNP
rs879421129 2062 dbSNP
rs1365816217 2065 dbSNP
rs146366938 2069 dbSNP
rs1030181369 2078 dbSNP
rs1444158516 2098 dbSNP
rs1021089277 2104 dbSNP
rs1010069412 2109 dbSNP
rs998634079 2115 dbSNP
rs1462620468 2121 dbSNP
rs903133618 2127 dbSNP
rs182285582 2134 dbSNP
rs1010898257 2139 dbSNP
rs905140923 2145 dbSNP
rs1046294115 2148 dbSNP
rs1358038841 2154 dbSNP
rs1312289139 2156 dbSNP
rs1013405790 2161 dbSNP
rs760486167 2162 dbSNP
rs897658579 2162 dbSNP
rs1036157237 2178 dbSNP
rs562392742 2180 dbSNP
rs1380927171 2182 dbSNP
rs941790805 2183 dbSNP
rs1299095170 2185 dbSNP
rs1424267364 2189 dbSNP
rs1383418083 2195 dbSNP
rs893816197 2197 dbSNP
rs545873125 2207 dbSNP
rs1271188287 2213 dbSNP
rs1446344160 2222 dbSNP
rs536710794 2227 dbSNP
rs1192189519 2228 dbSNP
rs1445120085 2230 dbSNP
rs1263604568 2233 dbSNP
rs1205218562 2239 dbSNP
rs1216804711 2243 dbSNP
rs1490094138 2249 dbSNP
rs1288900994 2252 dbSNP
rs1224138091 2259 dbSNP
rs1357634495 2264 dbSNP
rs1270197842 2268 dbSNP
rs1225685223 2277 dbSNP
rs1328496757 2283 dbSNP
rs1279266367 2285 dbSNP
rs908952034 2288 dbSNP
rs1352288902 2291 dbSNP
rs553720584 2292 dbSNP
rs142185447 2304 dbSNP
rs575033513 2306 dbSNP
rs1304996883 2307 dbSNP
rs1406088582 2310 dbSNP
rs554951759 2315 dbSNP
rs538576590 2320 dbSNP
rs775375402 2321 dbSNP
rs977010541 2323 dbSNP
rs569451730 2324 dbSNP
rs1479895370 2340 dbSNP
rs1266382061 2345 dbSNP
rs963928743 2353 dbSNP
rs1271697544 2354 dbSNP
rs1194542736 2355 dbSNP
rs914074164 2363 dbSNP
rs1259083916 2364 dbSNP
rs1402662470 2365 dbSNP
rs1400211198 2367 dbSNP
rs988298202 2376 dbSNP
rs1175774239 2381 dbSNP
rs1437469375 2391 dbSNP
rs1470602981 2393 dbSNP
rs113610876 2395 dbSNP
rs910219669 2404 dbSNP
rs1432028816 2406 dbSNP
rs1168988475 2407 dbSNP
rs1326971039 2409 dbSNP
rs1408098382 2415 dbSNP
rs1402441143 2416 dbSNP
rs1469161744 2418 dbSNP
rs370415795 2427 dbSNP
rs1475257150 2430 dbSNP
rs1192512090 2431 dbSNP
rs559228976 2442 dbSNP
rs1193532587 2446 dbSNP
rs148350456 2449 dbSNP
rs71569954 2451 dbSNP
rs969350625 2455 dbSNP
rs1239385567 2457 dbSNP
rs1030020993 2458 dbSNP
rs1265386262 2460 dbSNP
rs1240777054 2471 dbSNP
rs1202429302 2476 dbSNP
rs878943249 2477 dbSNP
rs1324195301 2481 dbSNP
rs570585459 2482 dbSNP
rs897715261 2485 dbSNP
rs1338586670 2486 dbSNP
rs1015203036 2487 dbSNP
rs1006036513 2490 dbSNP
rs1379021007 2499 dbSNP
rs1332025757 2503 dbSNP
rs190344827 2510 dbSNP
rs1050165302 2513 dbSNP
rs1021382589 2517 dbSNP
rs1011495377 2519 dbSNP
rs1414658388 2521 dbSNP
rs1406845214 2522 dbSNP
rs1156299071 2560 dbSNP
rs1441059578 2566 dbSNP
rs931686618 2569 dbSNP
rs1183444077 2570 dbSNP
rs894360403 2577 dbSNP
rs1433214819 2581 dbSNP
rs1380797200 2582 dbSNP
rs1239531910 2583 dbSNP
rs1336199855 2584 dbSNP
rs1446611083 2585 dbSNP
rs1055145785 2594 dbSNP
rs1225527957 2597 dbSNP
rs1408956933 2601 dbSNP
rs901511713 2602 dbSNP
rs1002603445 2604 dbSNP
rs1245093915 2606 dbSNP
rs1420714435 2608 dbSNP
rs1304337986 2612 dbSNP
rs1448568578 2617 dbSNP
rs527299156 2618 dbSNP
rs1169982225 2625 dbSNP
rs1476200673 2641 dbSNP
rs1315710914 2651 dbSNP
rs1421140169 2654 dbSNP
rs1380330766 2655 dbSNP
rs944299001 2657 dbSNP
rs914144397 2659 dbSNP
rs144406554 2660 dbSNP
rs1046513034 2664 dbSNP
rs548187169 2668 dbSNP
rs898003952 2669 dbSNP
rs866231429 2670 dbSNP
rs531530990 2677 dbSNP
rs1291103537 2686 dbSNP
rs796574436 2694 dbSNP
rs1357186408 2703 dbSNP
rs910764982 2706 dbSNP
rs759071995 2710 dbSNP
rs1216069019 2711 dbSNP
rs1357557044 2719 dbSNP
rs1314560071 2723 dbSNP
rs980827129 2744 dbSNP
rs932979908 2748 dbSNP
rs1246970139 2750 dbSNP
rs1385166167 2751 dbSNP
rs923060989 2752 dbSNP
rs1422288031 2753 dbSNP
rs114173535 2755 dbSNP
rs1166035832 2758 dbSNP
rs1057249 2766 dbSNP
rs1409903534 2769 dbSNP
rs992161274 2780 dbSNP
rs967062421 2785 dbSNP
rs1021431940 2788 dbSNP
rs545611019 2812 dbSNP
rs962295231 2824 dbSNP
rs1423069251 2825 dbSNP
rs1266110637 2827 dbSNP
rs374041465 2830 dbSNP
rs990361687 2834 dbSNP
rs1306867565 2836 dbSNP
rs1255897283 2838 dbSNP
rs1026919671 2842 dbSNP
rs958679458 2850 dbSNP
rs368208389 2852 dbSNP
rs377139040 2856 dbSNP
rs1014842793 2861 dbSNP
rs1162614651 2867 dbSNP
rs1034661895 2872 dbSNP
rs1444837144 2873 dbSNP
rs1369013635 2874 dbSNP
rs769988030 2876 dbSNP
rs1002247776 2877 dbSNP
rs906524720 2878 dbSNP
rs1024945887 2881 dbSNP
rs759619932 2882 dbSNP
rs897886416 2884 dbSNP
rs532421237 2896 dbSNP
rs776784848 2901 dbSNP
rs1028792194 2905 dbSNP
rs1429043304 2911 dbSNP
rs1174457689 2912 dbSNP
rs1435157593 2914 dbSNP
rs1268083751 2917 dbSNP
rs1176741152 2927 dbSNP
rs1236357358 2931 dbSNP
rs1480252717 2931 dbSNP
rs995946033 2931 dbSNP
rs1318261089 2933 dbSNP
rs1262285160 2936 dbSNP
rs560390978 2950 dbSNP
rs540759507 2952 dbSNP
rs186436905 2954 dbSNP
rs1051111186 2966 dbSNP
rs1040090769 2967 dbSNP
rs945714294 2968 dbSNP
rs933556340 2973 dbSNP
rs892749987 2977 dbSNP
rs113384641 2979 dbSNP
rs977033428 2981 dbSNP
rs544562051 2989 dbSNP
rs1290752383 3003 dbSNP
rs748831413 3004 dbSNP
rs1158474495 3007 dbSNP
rs78338735 3009 dbSNP
rs945813416 3011 dbSNP
rs914311287 3013 dbSNP
rs1382265128 3015 dbSNP
rs777586371 3018 dbSNP
rs1458184228 3025 dbSNP
rs990023823 3026 dbSNP
rs925455510 3027 dbSNP
rs1484025651 3028 dbSNP
rs958781852 3029 dbSNP
rs1237893628 3032 dbSNP
rs576021809 3033 dbSNP
rs1310849971 3036 dbSNP
rs1241442417 3043 dbSNP
rs948170724 3045 dbSNP
rs559164456 3046 dbSNP
rs917983536 3047 dbSNP
rs138157114 3051 dbSNP
rs1281840100 3052 dbSNP
rs1451901592 3053 dbSNP
rs1362495635 3056 dbSNP
rs41269511 3057 dbSNP
rs570522420 3059 dbSNP
rs1345324471 3060 dbSNP
rs1425273403 3062 dbSNP
rs147029665 3066 dbSNP
rs1487114804 3070 dbSNP
rs533938171 3071 dbSNP
rs897940187 3092 dbSNP
rs13375114 3096 dbSNP
rs1216750893 3105 dbSNP
rs41269509 3106 dbSNP
rs1006425505 3111 dbSNP
rs758888795 3117 dbSNP
rs889292948 3119 dbSNP
rs1351222322 3126 dbSNP
rs548204450 3136 dbSNP
rs984727900 3138 dbSNP
rs951920516 3140 dbSNP
rs1050579887 3144 dbSNP
rs531469243 3154 dbSNP
rs568812868 3157 dbSNP
rs1342670241 3160 dbSNP
rs995996753 3161 dbSNP
rs1424159569 3162 dbSNP
rs1388683816 3171 dbSNP
rs902075664 3173 dbSNP
rs1041394253 3176 dbSNP
rs965808129 3177 dbSNP
rs551910543 3178 dbSNP
rs867138422 3181 dbSNP
rs1479395647 3184 dbSNP
rs1267978239 3188 dbSNP
rs747287231 3192 dbSNP
rs1199815744 3202 dbSNP
rs1490910574 3205 dbSNP
rs1259115005 3206 dbSNP
rs1287139198 3216 dbSNP
rs1212115609 3229 dbSNP
rs778540651 3233 dbSNP
rs974083204 3234 dbSNP
rs1215318665 3235 dbSNP
rs554007914 3236 dbSNP
rs1317665443 3239 dbSNP
rs937071563 3246 dbSNP
rs927121678 3251 dbSNP
rs1279006984 3255 dbSNP
rs1404569964 3257 dbSNP
rs534124275 3265 dbSNP
rs560338584 3267 dbSNP
rs540347435 3274 dbSNP
rs1010350698 3275 dbSNP
rs891466886 3276 dbSNP
rs1169687777 3280 dbSNP
rs1463924324 3281 dbSNP
rs1222276896 3291 dbSNP
rs1170864761 3293 dbSNP
rs1477510087 3295 dbSNP
rs918492323 3301 dbSNP
rs972081698 3308 dbSNP
rs1166641110 3319 dbSNP
rs530246753 3324 dbSNP
rs561091559 3325 dbSNP
rs1452665328 3334 dbSNP
rs1250526594 3335 dbSNP
rs1197314865 3336 dbSNP
rs1407079044 3343 dbSNP
rs1001089955 3345 dbSNP
rs962032011 3350 dbSNP
rs1343198310 3351 dbSNP
rs1045234326 3359 dbSNP
rs544638429 3360 dbSNP
rs948221741 3373 dbSNP
rs1444482144 3384 dbSNP
rs1402150752 3385 dbSNP
rs1331822309 3388 dbSNP
rs1413537982 3394 dbSNP
rs1016233914 3413 dbSNP
rs1422673423 3415 dbSNP
rs918037848 3422 dbSNP
rs1478035274 3426 dbSNP
rs1160706370 3428 dbSNP
rs1177266782 3436 dbSNP
rs1459494389 3437 dbSNP
rs575963004 3440 dbSNP
rs1056563043 3446 dbSNP
rs953467761 3450 dbSNP
rs1440905085 3464 dbSNP
rs1281061966 3465 dbSNP
rs940733006 3467 dbSNP
rs6943 3468 dbSNP
rs1419941966 3469 dbSNP
rs985168532 3476 dbSNP
rs1237807893 3479 dbSNP
rs1379093424 3480 dbSNP
rs1309679682 3492 dbSNP
rs545756786 3496 dbSNP
rs1447105726 3518 dbSNP
rs1357062548 3521 dbSNP
rs1801788 3528 dbSNP
rs1176890305 3529 dbSNP
rs997627183 3532 dbSNP
rs1259397011 3533 dbSNP
rs921826791 3537 dbSNP
rs1186189591 3545 dbSNP
rs1359292016 3554 dbSNP
rs181770512 3560 dbSNP
rs1486304423 3563 dbSNP
rs974612847 3563 dbSNP
rs1381546432 3568 dbSNP
rs141652426 3570 dbSNP
rs757374431 3573 dbSNP
rs1471980342 3578 dbSNP
rs1239586647 3580 dbSNP
rs1041950517 3588 dbSNP
rs1009890707 3589 dbSNP
rs1009988631 3593 dbSNP
rs892800517 3596 dbSNP
rs955957110 3597 dbSNP
rs551514878 3602 dbSNP
rs190123560 3603 dbSNP
rs373164994 3604 dbSNP
rs554240949 3615 dbSNP
rs372895144 3618 dbSNP
rs537456313 3626 dbSNP
rs1045619074 3631 dbSNP
rs949844844 3639 dbSNP
rs1018525669 3643 dbSNP
rs972655151 3644 dbSNP
rs1306185957 3647 dbSNP
rs200173223 3649 dbSNP
rs796564682 3649 dbSNP
rs1057280 3650 dbSNP
rs1295260942 3650 dbSNP
rs1182857149 3651 dbSNP
rs1213674348 3651 dbSNP
rs368832722 3654 dbSNP
rs1490532318 3655 dbSNP
rs2491131 3655 dbSNP
rs28673561 3656 dbSNP
rs1322008557 3657 dbSNP
rs866951785 3658 dbSNP
rs1009965019 3659 dbSNP
rs1319903364 3659 dbSNP
rs1291716080 3660 dbSNP
rs1141367 3661 dbSNP
rs1449748138 3662 dbSNP
rs71644190 3662 dbSNP
rs1001203286 3663 dbSNP
rs2491130 3664 dbSNP
rs796674636 3665 dbSNP
rs905816559 3665 dbSNP
rs1467495108 3666 dbSNP
rs552047573 3667 dbSNP
rs1434915795 3668 dbSNP
rs1352164191 3669 dbSNP
rs796441004 3670 dbSNP
rs45440502 3671 dbSNP
rs10624994 3672 dbSNP
rs1421954359 3672 dbSNP
rs200633685 3673 dbSNP
rs11338317 3675 dbSNP
rs1189582270 3675 dbSNP
rs1214257795 3675 dbSNP
rs1255955165 3675 dbSNP
rs1299954018 3675 dbSNP
rs1365946616 3675 dbSNP
rs1424518123 3675 dbSNP
rs144394334 3675 dbSNP
rs148019842 3675 dbSNP
rs1487461894 3675 dbSNP
rs368631325 3675 dbSNP
rs869138167 3675 dbSNP
rs1181843818 3676 dbSNP
rs1282229598 3677 dbSNP
rs1294575093 3677 dbSNP
rs1446705299 3679 dbSNP
rs907685495 3679 dbSNP
rs200711823 3683 dbSNP
rs113772523 3684 dbSNP
rs765382241 3684 dbSNP
rs781009788 3684 dbSNP
rs142716846 3686 dbSNP
rs139393886 3687 dbSNP
rs200724045 3687 dbSNP
rs1377346877 3688 dbSNP
rs10711024 3691 dbSNP
rs1434922599 3691 dbSNP
rs779977815 3691 dbSNP
rs796974436 3691 dbSNP
rs1425961712 3693 dbSNP
rs1194140239 3708 dbSNP
rs1439034508 3709 dbSNP
rs1236114418 3711 dbSNP
rs1200349895 3716 dbSNP
rs909226074 3720 dbSNP
rs984780341 3744 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000336798.7 | 3UTR | UCAAGACAUAUCACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000336798.7 | 3UTR | UCAAGACAUAUCACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells 0.524 5.1e-3 0.456 1.4e-2 23 Click to see details
GSE28544 Breast cancer 0.499 6.5e-3 0.514 5.1e-3 24 Click to see details
GSE19350 CNS germ cell tumors 0.486 5.5e-2 0.559 2.9e-2 12 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.319 6.0e-2 -0.336 5.0e-2 25 Click to see details
GSE28260 Renal cortex and medulla -0.402 8.7e-2 -0.324 1.4e-1 13 Click to see details
GSE38226 Liver fibrosis -0.277 1.1e-1 -0.235 1.5e-1 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.163 2.5e-1 -0.223 1.7e-1 20 Click to see details
GSE17498 Multiple myeloma 0.064 3.5e-1 0.104 2.6e-1 40 Click to see details
GSE32688 Pancreatic cancer -0.068 3.6e-1 0.000 5.0e-1 32 Click to see details
GSE21687 Ependynoma primary tumors -0.045 3.6e-1 0.094 2.3e-1 64 Click to see details
GSE26953 Aortic valvular endothelial cells -0.015 4.7e-1 -0.079 3.6e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells -0.015 4.7e-1 -0.079 3.6e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
-0.015 4.7e-1 -0.079 3.6e-1 24 Click to see details
-0.015 4.7e-1 -0.079 3.6e-1 24 Click to see details
-0.015 4.7e-1 -0.079 3.6e-1 24 Click to see details
65 hsa-miR-124-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT064177 KIAA1804 mitogen-activated protein kinase kinase kinase 21 2 2
MIRT069736 FOXG1 forkhead box G1 2 4
MIRT086429 NABP1 nucleic acid binding protein 1 2 6
MIRT105334 SLC7A2 solute carrier family 7 member 2 2 4
MIRT110455 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT172998 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT196428 TAOK1 TAO kinase 1 2 14
MIRT325704 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT365670 TSC22D3 TSC22 domain family member 3 2 4
MIRT365873 XIAP X-linked inhibitor of apoptosis 2 2
MIRT404126 ASB1 ankyrin repeat and SOCS box containing 1 2 2
MIRT404626 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT405284 ARF1 ADP ribosylation factor 1 2 2
MIRT406099 PAGR1 PAXIP1 associated glutamate rich protein 1 2 2
MIRT446627 SDC3 syndecan 3 2 2
MIRT446906 RGS5 regulator of G protein signaling 5 2 2
MIRT461790 FXR2 FMR1 autosomal homolog 2 2 2
MIRT463982 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT464204 VGLL4 vestigial like family member 4 2 2
MIRT472790 MTMR4 myotubularin related protein 4 2 4
MIRT473485 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT481124 AZIN1 antizyme inhibitor 1 2 4
MIRT485060 SUCO SUN domain containing ossification factor 2 2
MIRT487343 HLA-DRA major histocompatibility complex, class II, DR alpha 2 2
MIRT491948 VPS52 VPS52, GARP complex subunit 2 2
MIRT497208 CDH7 cadherin 7 2 2
MIRT497476 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT528203 NELFE negative elongation factor complex member E 2 2
MIRT529255 TRIM4 tripartite motif containing 4 2 4
MIRT530096 PSAPL1 prosaposin like 1 (gene/pseudogene) 2 2
MIRT530597 C7orf33 chromosome 7 open reading frame 33 2 4
MIRT534980 PSAT1 phosphoserine aminotransferase 1 2 4
MIRT538326 CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2 2
MIRT561237 ZNF652 zinc finger protein 652 2 2
MIRT562035 KRAS KRAS proto-oncogene, GTPase 2 2
MIRT563120 THAP5 THAP domain containing 5 2 2
MIRT563538 RBM41 RNA binding motif protein 41 2 2
MIRT566037 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT566505 PAWR pro-apoptotic WT1 regulator 2 2
MIRT566745 MRPL35 mitochondrial ribosomal protein L35 2 2
MIRT566850 LRRC58 leucine rich repeat containing 58 2 2
MIRT568077 CELF2 CUGBP Elav-like family member 2 2 2
MIRT576826 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT608870 NR2E1 nuclear receptor subfamily 2 group E member 1 2 4
MIRT611997 VAC14 Vac14, PIKFYVE complex component 2 2
MIRT614054 FAM89A family with sequence similarity 89 member A 2 2
MIRT618800 SPATA21 spermatogenesis associated 21 2 2
MIRT619389 RSPH3 radial spoke head 3 homolog 2 2
MIRT622282 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT624026 EN2 engrailed homeobox 2 2 2
MIRT626000 MPEG1 macrophage expressed 1 2 2
MIRT641792 USP32 ubiquitin specific peptidase 32 2 2
MIRT651599 WDFY2 WD repeat and FYVE domain containing 2 2 2
MIRT659662 CDC73 cell division cycle 73 2 2
MIRT663010 KIAA1586 KIAA1586 2 2
MIRT663561 ASTN2 astrotactin 2 2 2
MIRT669312 C16orf72 chromosome 16 open reading frame 72 2 2
MIRT685216 POTED POTE ankyrin domain family member D 2 2
MIRT695757 ZNF117 zinc finger protein 117 2 2
MIRT697909 TXNRD1 thioredoxin reductase 1 2 2
MIRT707181 RPH3A rabphilin 3A 2 2
MIRT707214 TRIM13 tripartite motif containing 13 2 2
MIRT707478 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT719507 LMAN2L lectin, mannose binding 2 like 2 2
MIRT755814 PARP1 poly(ADP-ribose) polymerase 1 2 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-124 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) NULL 16078949 Microarray hepatocytes 23107762 2013 up-regulated
miR-124 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
miR-124 Vorinostat (SAHA) approved 5311 Microarray A549 human non-small cell lung cancer cells 19513533 2009 up-regulated
miR-124 Cocaine NULL 446220 Quantitative real-time PCR HEK293 cells or rat brain parts 19703567 2009 down-regulated
miR-124 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-124 Chaihu Shugan San NULL NULL Microarray hippocampus 23947143 2013 up-regualted
miR-124 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-124 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) NULL 15625 Microarray embryos 22921993 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-124-5p Paclitaxel 36314 NSC125973 approved resistant High Laryngeal Cancer cell line (Hep2)
hsa-miR-124-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (MGC803)
hsa-miR-124-5p Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-miR-124-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-124-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-124-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR20)
hsa-miR-124-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-124-5p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-124-5p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-124-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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