miRTarBase - #MIRT446882


—
pre-miRNA Information
pre-miRNA hsa-mir-4524b   
Genomic Coordinates chr17: 69099542 - 69099656
Description Homo sapiens miR-4524b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4524b-3p
Sequence 66| GAGACAGGUUCAUGCUGCUA |85
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1263495678 1 dbSNP
rs1350790266 9 dbSNP
rs1322445998 14 dbSNP
Putative Targets

Gene Information
Gene Symbol ZNF554   
Synonyms -
Description zinc finger protein 554
Transcript NM_001102651   
Expression
Putative miRNA Targets on ZNF554
3'UTR of ZNF554
(miRNA target sites are highlighted)		 
>ZNF554|NM_001102651|3'UTR
   1 CAATTGCACGCTGCTTTGTAAGCCACTTTTTAGTACTCTGACACATACATGTGGTTATCTTTTGCCCTGTTGTGATGGAT
  81 AATTTGAAAAGAAGTGGGTTTATGTCACCTTCTCACCTTCTTATAAGAAAGCTCTGAGAATGGGCATTTTTGTATTTTGT
 161 TGTTGTTGTTGAGATGGAGTCTGCCACCCAGGCTGGAGTCCAGTGGCGTGATCATACCTCACTGCAGCTTCAACTTCCTG
 241 GGCTCAAGTAATCCTCCCACCCCAGCCTCCCAGGTAGCTAGTACTATAGGTGTGCACCACCACGCCCAGCAAATTTTTAA
 321 ATTTATTATAGAGTGGGAGGCAGGGTGCGGTGGCTCATGCCTATAATCCTAACACTTTAGGAGGCCGAGGCGGGTGGATC
 401 ATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCTGTCTCTACTAAAAATACAAAAAAGTAGCCGGGC
 481 GTGGTGGTGGGCGCCTGTAGTCCCAACTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAGGTGGAGCTTGC
 561 AGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGGAGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAATTATA
 641 GAGTTGGGGTCTTGCTACATTGCCAAGACTGGTCTTGAACTCCTGGGGTCAAGCATCCTCCTGTCTTGGCCTCCCAAAGT
 721 GTTGGGATTAGAAGCATGAGCCGCTGTGCCCAGCCTGACGGGGCCTTTTAGTGGGAGGAGTTGCCATTACACTACGTCCA
 801 GTAAGCTCCAGACTTTCGGAAAAGATTGGTGGACGGGAATGCTGTCATGGATGGGATCTTGCCAAGAACCATCACGTGTT
 881 AATTTAGTTGCTTAAACAAAAGGTGTTCTGTTTCTTAACTACTTCTGTGTCTTTACTTTTTATTTCATTGTTCATTGTTT
 961 TTATTTTAATATTCTTTTCTGGGTTTATATGAGACGAGTTTTCACTCTGTTGCTGAGGCTGAAGTGCAGTGGCGTGATCA
1041 TAGCTCCCTGTAGTCAGCCTTCATCTCCTGGACTCAAGCAATCCTCCCACCTCAGCCTCTCCGGTAGCTGGGACTACACA
1121 TGTGCACCGCTACCACACCCAGCTAAATTTTTTTTTTGTATTTTTGTAGTGATGGGCTTTCACCAGGTTGCCCAGGCTGG
1201 TCTCAAACTCCTGAGCTCAAGCAATCCACCCACCTTGGCCTCCCAAAGTGCTGGTATTACAGGTGTGAGCCACCGTGCTG
1281 GTATTACGGGTGTGAGCCACTGTGCTGGGATTACGGGCGTGAGCTGCCCATGCTGGGATTACGGGTGTGAGCCACCGTGC
1361 TGGTATTACGGGTGTGAGCCACCGTGCTGGGATTACGGGCGTGAGCCACTGTGCTGGGATTACGGGCGCGAGCCACTGTG
1441 CTGGGATTACAGGTGTGAGCCACCCTGCTGGGATTATGGGTGCGAGCCGCCGTGCTGGGATTACAGGTGTGAACCACTGC
1521 TCCTGGCCTTTATTTCAGCATTCTGTTTCAGTGTTTCACATTGGCCACTTAGCTAGATCCGTTTGTCTTCTGCAGTACTG
1601 TGCTGATCCAGAGTATATGCTAAGACGGAAAGCGCTTTGGAGGTAAAGTTTAAAAAATACAAGGGCTTCAAAATAGTACT
1681 AGTAATTTGATCCATTCACAAAAGGACAAAGGCTGGACAGAGACGTGAAGAAATGAATCATTTACGCAATGATTGGGGTG
1761 TTCCAATTATGTGTGATTTTGTGTTTTCTGCCGTTTCATTTTGTATTGCCATAATCATTTTGACAATGAATACAAATCAA
1841 ATAGCACCCAAAATTGTGAAGGATACGGAACCTCATTGATGAG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aucgUCGUACUUGGACAGAg 5'
              |||||   ||||||| 
Target 5' gtcaAGCATCCTCCTGTCTt 3'
 688 - 707 156.00 -16.30
2 
miRNA  3' aucGUCGUACUU--GGACAGAg 5'
             ||  :||||  ||||||| 
Target 5' taaCACAGTGAAACCCTGTCTc 3'
 431 - 452 155.00 -17.30
3 
miRNA  3' aucGUCGUACUUGGACAGAg 5'
             ||||||   :||||:| 
Target 5' tttCAGCAT---TCTGTTTc 3'
 1533 - 1549 126.00 -16.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30131317 65 COSMIC
COSN30461173 110 COSMIC
COSN24834656 170 COSMIC
COSN1764212 245 COSMIC
COSN7052452 615 COSMIC
COSN7120858 760 COSMIC
COSN27575229 796 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1225344498 3 dbSNP
rs775478154 5 dbSNP
rs760982581 7 dbSNP
rs1016753999 8 dbSNP
rs188183451 10 dbSNP
rs750018067 11 dbSNP
rs997070924 12 dbSNP
rs1340967439 13 dbSNP
rs1212411418 15 dbSNP
rs1291427663 16 dbSNP
rs762720202 17 dbSNP
rs1028170115 18 dbSNP
rs765998053 18 dbSNP
rs1045031919 24 dbSNP
rs1208104439 26 dbSNP
rs575554970 27 dbSNP
rs751120323 37 dbSNP
rs754849116 38 dbSNP
rs781224191 40 dbSNP
rs752711595 41 dbSNP
rs1414666421 47 dbSNP
rs1460930596 49 dbSNP
rs1162858008 50 dbSNP
rs755907820 51 dbSNP
rs1402990030 55 dbSNP
rs369780432 62 dbSNP
rs1329234490 65 dbSNP
rs542720826 68 dbSNP
rs1410754140 69 dbSNP
rs1381320759 70 dbSNP
rs1421870620 73 dbSNP
rs1240321231 77 dbSNP
rs1280911384 82 dbSNP
rs1348156082 97 dbSNP
rs1477566025 98 dbSNP
rs905291570 115 dbSNP
rs201305142 117 dbSNP
rs867654255 117 dbSNP
rs560932452 118 dbSNP
rs1489999133 119 dbSNP
rs1279733635 127 dbSNP
rs913535005 140 dbSNP
rs1462954536 141 dbSNP
rs1032826340 143 dbSNP
rs966340466 156 dbSNP
rs772812826 157 dbSNP
rs1270385356 177 dbSNP
rs1217607939 178 dbSNP
rs1323671674 180 dbSNP
rs1243075354 184 dbSNP
rs1221667865 194 dbSNP
rs1458260308 202 dbSNP
rs979103658 208 dbSNP
rs925003167 209 dbSNP
rs1009737650 212 dbSNP
rs1352524897 214 dbSNP
rs1329610255 215 dbSNP
rs937807153 216 dbSNP
rs965588350 217 dbSNP
rs1178605719 224 dbSNP
rs976157354 226 dbSNP
rs1425031243 228 dbSNP
rs1055674764 229 dbSNP
rs1471387585 230 dbSNP
rs953263305 234 dbSNP
rs984587198 242 dbSNP
rs1470837682 248 dbSNP
rs757879710 251 dbSNP
rs1201192219 252 dbSNP
rs949578221 255 dbSNP
rs1311557545 260 dbSNP
rs1284933766 262 dbSNP
rs1405334765 268 dbSNP
rs1370996883 270 dbSNP
rs1048017787 278 dbSNP
rs1391438989 280 dbSNP
rs886725944 287 dbSNP
rs1439133267 297 dbSNP
rs1383717198 298 dbSNP
rs193262022 304 dbSNP
rs528213349 305 dbSNP
rs900555844 309 dbSNP
rs1358626876 314 dbSNP
rs917832972 319 dbSNP
rs996293732 322 dbSNP
rs1028535050 323 dbSNP
rs1444900443 327 dbSNP
rs949279075 346 dbSNP
rs955214601 349 dbSNP
rs905219049 350 dbSNP
rs1222129345 354 dbSNP
rs539798418 355 dbSNP
rs1260799648 357 dbSNP
rs1217940034 360 dbSNP
rs1001258019 361 dbSNP
rs1008047701 362 dbSNP
rs892548793 364 dbSNP
rs1009748930 366 dbSNP
rs1020823122 372 dbSNP
rs1317489645 376 dbSNP
rs1198111961 378 dbSNP
rs1394477858 379 dbSNP
rs564905575 387 dbSNP
rs73526343 388 dbSNP
rs997080355 391 dbSNP
rs1028980714 392 dbSNP
rs185413930 393 dbSNP
rs964275566 396 dbSNP
rs569895661 403 dbSNP
rs1174055590 409 dbSNP
rs1428471290 411 dbSNP
rs1387438841 416 dbSNP
rs959361041 417 dbSNP
rs990589700 418 dbSNP
rs1393620650 428 dbSNP
rs1015974875 430 dbSNP
rs1262326540 439 dbSNP
rs1303373824 448 dbSNP
rs961731163 456 dbSNP
rs751453986 457 dbSNP
rs531045609 458 dbSNP
rs1242955969 477 dbSNP
rs75377257 477 dbSNP
rs1282998172 478 dbSNP
rs1047966261 481 dbSNP
rs567623880 482 dbSNP
rs781258601 483 dbSNP
rs1338496636 484 dbSNP
rs535118985 485 dbSNP
rs1406089240 486 dbSNP
rs1367915584 492 dbSNP
rs1038083001 493 dbSNP
rs764671665 494 dbSNP
rs1373248915 511 dbSNP
rs1171930830 515 dbSNP
rs1338824746 518 dbSNP
rs1223399551 521 dbSNP
rs1422244946 532 dbSNP
rs1200138678 533 dbSNP
rs932024321 537 dbSNP
rs1481368029 538 dbSNP
rs1265012588 544 dbSNP
rs79667368 545 dbSNP
rs890577163 546 dbSNP
rs1200728221 560 dbSNP
rs1316217590 562 dbSNP
rs148864349 569 dbSNP
rs2317036 570 dbSNP
rs902411616 572 dbSNP
rs781537182 575 dbSNP
rs1195158424 576 dbSNP
rs955316228 581 dbSNP
rs945419993 582 dbSNP
rs1000809696 595 dbSNP
rs1397630667 599 dbSNP
rs1299564829 602 dbSNP
rs1463729448 607 dbSNP
rs1041247628 608 dbSNP
rs988553038 615 dbSNP
rs1481377703 616 dbSNP
rs1337936130 619 dbSNP
rs1021037186 620 dbSNP
rs10695177 620 dbSNP
rs1204342129 620 dbSNP
rs1257512312 620 dbSNP
rs1456567297 620 dbSNP
rs3059202 620 dbSNP
rs1347780085 625 dbSNP
rs1254811526 629 dbSNP
rs1233123827 631 dbSNP
rs959079304 632 dbSNP
rs1336791050 635 dbSNP
rs557320354 636 dbSNP
rs1163710947 643 dbSNP
rs1366934225 644 dbSNP
rs1422312031 645 dbSNP
rs1375608073 647 dbSNP
rs990927656 648 dbSNP
rs575494088 649 dbSNP
rs1302165214 651 dbSNP
rs970489262 657 dbSNP
rs1363013181 661 dbSNP
rs1454238596 664 dbSNP
rs1365339198 679 dbSNP
rs997406925 683 dbSNP
rs1438100287 684 dbSNP
rs147998793 685 dbSNP
rs1294047797 686 dbSNP
rs536135748 688 dbSNP
rs908059539 694 dbSNP
rs942219593 703 dbSNP
rs1200444557 705 dbSNP
rs1317196110 727 dbSNP
rs1357394661 735 dbSNP
rs1005887740 737 dbSNP
rs973688593 743 dbSNP
rs922210081 744 dbSNP
rs554752980 749 dbSNP
rs971815450 750 dbSNP
rs968564253 755 dbSNP
rs1449771031 758 dbSNP
rs767427441 759 dbSNP
rs1206732456 760 dbSNP
rs779308356 761 dbSNP
rs1427808687 762 dbSNP
rs936548945 764 dbSNP
rs1385598901 770 dbSNP
rs890524793 773 dbSNP
rs1164519124 788 dbSNP
rs879621639 796 dbSNP
rs1042181321 797 dbSNP
rs913876406 799 dbSNP
rs1265910600 806 dbSNP
rs1215051041 810 dbSNP
rs528492889 818 dbSNP
rs557724113 819 dbSNP
rs1229695122 830 dbSNP
rs780257734 835 dbSNP
rs1283124695 836 dbSNP
rs1227460926 838 dbSNP
rs932842816 840 dbSNP
rs1050311429 844 dbSNP
rs1296308484 847 dbSNP
rs895095273 852 dbSNP
rs564726458 853 dbSNP
rs1011897810 854 dbSNP
rs1455654692 862 dbSNP
rs377427509 866 dbSNP
rs1287525849 870 dbSNP
rs112155892 876 dbSNP
rs749504482 877 dbSNP
rs1006185866 899 dbSNP
rs970441713 900 dbSNP
rs1192200072 915 dbSNP
rs983201663 917 dbSNP
rs1015065925 918 dbSNP
rs545283295 922 dbSNP
rs963568966 928 dbSNP
rs1270060214 931 dbSNP
rs1224187182 932 dbSNP
rs1015783091 938 dbSNP
rs974018308 948 dbSNP
rs375258613 954 dbSNP
rs932252906 962 dbSNP
rs987401730 963 dbSNP
rs911913879 973 dbSNP
rs546751137 988 dbSNP
rs970851891 994 dbSNP
rs946098667 996 dbSNP
rs1002048176 997 dbSNP
rs1041793545 998 dbSNP
rs531130098 1005 dbSNP
rs768732798 1009 dbSNP
rs926074400 1010 dbSNP
rs1466328156 1012 dbSNP
rs191333202 1020 dbSNP
rs1054052953 1032 dbSNP
rs957994198 1033 dbSNP
rs566773528 1034 dbSNP
rs567854826 1035 dbSNP
rs1182148309 1040 dbSNP
rs529063403 1041 dbSNP
rs1046059080 1043 dbSNP
rs1197409132 1050 dbSNP
rs1324210101 1054 dbSNP
rs1280708648 1060 dbSNP
rs1217372834 1061 dbSNP
rs368027279 1066 dbSNP
rs1279862491 1069 dbSNP
rs1004583983 1077 dbSNP
rs1459584576 1081 dbSNP
rs1180827972 1082 dbSNP
rs1329422072 1094 dbSNP
rs1446198042 1102 dbSNP
rs528567234 1103 dbSNP
rs1178955472 1104 dbSNP
rs1413253022 1113 dbSNP
rs760708269 1114 dbSNP
rs1159558544 1117 dbSNP
rs1441196371 1118 dbSNP
rs1235922188 1119 dbSNP
rs1177597075 1121 dbSNP
rs1461408193 1124 dbSNP
rs1420457012 1125 dbSNP
rs775574335 1129 dbSNP
rs932705132 1130 dbSNP
rs1049938833 1134 dbSNP
rs747057004 1139 dbSNP
rs1470509520 1143 dbSNP
rs1037283110 1148 dbSNP
rs879795870 1148 dbSNP
rs769264025 1152 dbSNP
rs1446322273 1158 dbSNP
rs1339260073 1159 dbSNP
rs897405866 1159 dbSNP
rs1404611199 1160 dbSNP
rs1451977061 1161 dbSNP
rs993134096 1162 dbSNP
rs1446466792 1174 dbSNP
rs547117571 1176 dbSNP
rs1029586594 1183 dbSNP
rs1378818561 1184 dbSNP
rs550390766 1185 dbSNP
rs1157743645 1188 dbSNP
rs1423975014 1195 dbSNP
rs1415341219 1196 dbSNP
rs953633863 1201 dbSNP
rs987687259 1228 dbSNP
rs1482901175 1248 dbSNP
rs1263877789 1252 dbSNP
rs911861323 1256 dbSNP
rs1239710077 1262 dbSNP
rs1285031893 1262 dbSNP
rs1033422103 1264 dbSNP
rs1306567860 1265 dbSNP
rs1314978204 1265 dbSNP
rs967345922 1268 dbSNP
rs1226628510 1271 dbSNP
rs958135616 1273 dbSNP
rs977432709 1275 dbSNP
rs926042619 1276 dbSNP
rs936112784 1282 dbSNP
rs369788375 1283 dbSNP
rs1162233665 1287 dbSNP
rs777100894 1288 dbSNP
rs568808763 1289 dbSNP
rs571528042 1291 dbSNP
rs373931085 1292 dbSNP
rs947918345 1293 dbSNP
rs1210172316 1294 dbSNP
rs966578230 1299 dbSNP
rs1219604859 1300 dbSNP
rs56010141 1302 dbSNP
rs1258776372 1303 dbSNP
rs1221011494 1308 dbSNP
rs1321384059 1310 dbSNP
rs1277993482 1316 dbSNP
rs1046337123 1319 dbSNP
rs906487264 1320 dbSNP
rs1370141197 1321 dbSNP
rs1291498740 1324 dbSNP
rs1457085915 1325 dbSNP
rs1400409443 1326 dbSNP
rs1464026662 1327 dbSNP
rs976767577 1327 dbSNP
rs1422772086 1330 dbSNP
rs1199462734 1331 dbSNP
rs926431375 1338 dbSNP
rs1481334753 1343 dbSNP
rs371165269 1344 dbSNP
rs1004531429 1345 dbSNP
rs56065950 1347 dbSNP
rs55780459 1349 dbSNP
rs922566500 1352 dbSNP
rs1175048977 1357 dbSNP
rs569127316 1358 dbSNP
rs536559896 1364 dbSNP
rs55660536 1365 dbSNP
rs1299573788 1367 dbSNP
rs1385879023 1369 dbSNP
rs898883209 1370 dbSNP
rs56309832 1371 dbSNP
rs1443999738 1372 dbSNP
rs1029125483 1374 dbSNP
rs1173152772 1375 dbSNP
rs953682875 1382 dbSNP
rs1009055470 1384 dbSNP
rs147704774 1385 dbSNP
rs1037129448 1392 dbSNP
rs55877321 1397 dbSNP
rs977380484 1398 dbSNP
rs1249894916 1399 dbSNP
rs1297811292 1400 dbSNP
rs925960041 1401 dbSNP
rs114347844 1402 dbSNP
rs1405300247 1403 dbSNP
rs56372229 1403 dbSNP
rs1354835871 1406 dbSNP
rs1284913850 1410 dbSNP
rs56379421 1411 dbSNP
rs906220238 1414 dbSNP
rs1218513115 1415 dbSNP
rs373645526 1420 dbSNP
rs576547023 1424 dbSNP
rs947864951 1425 dbSNP
rs1273437004 1428 dbSNP
rs543775552 1429 dbSNP
rs184287792 1430 dbSNP
rs115230208 1431 dbSNP
rs1036002841 1436 dbSNP
rs1029841 1438 dbSNP
rs930378821 1439 dbSNP
rs1187612641 1441 dbSNP
rs151211646 1446 dbSNP
rs1408258446 1447 dbSNP
rs1168086889 1452 dbSNP
rs1214018573 1455 dbSNP
rs888912458 1463 dbSNP
rs1284303102 1465 dbSNP
rs1366310923 1465 dbSNP
rs2012992 1466 dbSNP
rs546761400 1478 dbSNP
rs140402279 1480 dbSNP
rs532657581 1482 dbSNP
rs550954178 1483 dbSNP
rs1418137305 1484 dbSNP
rs1301536303 1485 dbSNP
rs1363408333 1489 dbSNP
rs72982740 1490 dbSNP
rs188648699 1492 dbSNP
rs548495131 1493 dbSNP
rs1212265375 1498 dbSNP
rs1478401288 1503 dbSNP
rs1265798606 1506 dbSNP
rs1191903411 1507 dbSNP
rs957593054 1508 dbSNP
rs991544344 1511 dbSNP
rs200942202 1514 dbSNP
rs1290198797 1517 dbSNP
rs1211261115 1520 dbSNP
rs972895804 1523 dbSNP
rs1023451570 1533 dbSNP
rs1224172435 1537 dbSNP
rs1219178324 1541 dbSNP
rs150383493 1549 dbSNP
rs1276092323 1562 dbSNP
rs1289234408 1576 dbSNP
rs1331438519 1578 dbSNP
rs918729637 1582 dbSNP
rs1407281752 1584 dbSNP
rs1392390807 1592 dbSNP
rs981911353 1594 dbSNP
rs927797524 1599 dbSNP
rs1244308679 1601 dbSNP
rs1426475782 1604 dbSNP
rs1474692664 1604 dbSNP
rs940548172 1605 dbSNP
rs1188507166 1607 dbSNP
rs533956896 1607 dbSNP
rs1029843 1628 dbSNP
rs1475331318 1630 dbSNP
rs1029844 1634 dbSNP
rs1161896172 1635 dbSNP
rs1198673545 1639 dbSNP
rs1319353475 1642 dbSNP
rs138026251 1643 dbSNP
rs1213913034 1649 dbSNP
rs555727751 1658 dbSNP
rs1276334633 1666 dbSNP
rs1318770907 1682 dbSNP
rs1346776511 1686 dbSNP
rs1438883950 1688 dbSNP
rs1368997381 1692 dbSNP
rs1325327375 1693 dbSNP
rs1447665553 1694 dbSNP
rs1432737672 1708 dbSNP
rs141052938 1713 dbSNP
rs1169030361 1715 dbSNP
rs78380586 1716 dbSNP
rs561659475 1724 dbSNP
rs1174639442 1725 dbSNP
rs564795372 1726 dbSNP
rs1394149089 1727 dbSNP
rs902368612 1732 dbSNP
rs573122761 1734 dbSNP
rs777651735 1736 dbSNP
rs1458759626 1738 dbSNP
rs998024366 1740 dbSNP
rs999066505 1746 dbSNP
rs746083984 1747 dbSNP
rs1312436478 1749 dbSNP
rs1355259140 1753 dbSNP
rs1224027302 1754 dbSNP
rs1007307256 1771 dbSNP
rs1286727867 1772 dbSNP
rs893411062 1773 dbSNP
rs1016913695 1780 dbSNP
rs1379227842 1780 dbSNP
rs1208572807 1782 dbSNP
rs1244363589 1784 dbSNP
rs962783306 1787 dbSNP
rs1442162633 1789 dbSNP
rs758715185 1793 dbSNP
rs181759112 1794 dbSNP
rs1181875091 1798 dbSNP
rs1029845 1811 dbSNP
rs1433288224 1812 dbSNP
rs186116193 1832 dbSNP
rs768695170 1838 dbSNP
rs1441091764 1839 dbSNP
rs1405171000 1840 dbSNP
rs144671774 1842 dbSNP
rs1409805777 1847 dbSNP
rs971963249 1852 dbSNP
rs138591062 1858 dbSNP
rs1485256393 1860 dbSNP
rs927545087 1864 dbSNP
rs952027107 1866 dbSNP
rs766116681 1867 dbSNP
rs990904741 1868 dbSNP
rs910236849 1869 dbSNP
rs944420420 1877 dbSNP
rs1040091308 1880 dbSNP
rs1286532130 1883 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aucgUCGUACUUGGACAgag 5'
              |||||   |||||   
Target 5' -ucaAGCAUCCUCCUGU--- 3'
 		1 - 16
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000317243.5 | 3UTR | UCAAGCAUCCUCCUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
175 hsa-miR-4524b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT064889 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT075345 SF3B3 splicing factor 3b subunit 3 2 2
MIRT094174 PCGF3 polycomb group ring finger 3 2 6
MIRT100109 ABT1 activator of basal transcription 1 2 8
MIRT102242 HBP1 HMG-box transcription factor 1 2 2
MIRT124918 HCCS holocytochrome c synthase 2 2
MIRT140195 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT193891 HACD3 3-hydroxyacyl-CoA dehydratase 3 2 2
MIRT265634 LDHA lactate dehydrogenase A 2 2
MIRT303878 VAMP8 vesicle associated membrane protein 8 2 2
MIRT409756 CRTAP cartilage associated protein 2 4
MIRT441503 SPG20 spartin 2 6
MIRT446882 ZNF554 zinc finger protein 554 2 2
MIRT447093 COPRS coordinator of PRMT5 and differentiation stimulator 2 2
MIRT449987 AEN apoptosis enhancing nuclease 2 2
MIRT452116 IFITM1 interferon induced transmembrane protein 1 2 2
MIRT452654 ZNF33A zinc finger protein 33A 2 2
MIRT453886 IFRD1 interferon related developmental regulator 1 2 12
MIRT454143 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 2
MIRT454501 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT456633 ARMCX6 armadillo repeat containing, X-linked 6 2 2
MIRT457021 ACADSB acyl-CoA dehydrogenase, short/branched chain 2 2
MIRT457055 NEGR1 neuronal growth regulator 1 2 2
MIRT457335 REG4 regenerating family member 4 2 2
MIRT457421 CASC5 kinetochore scaffold 1 2 2
MIRT457940 LCE1A late cornified envelope 1A 2 2
MIRT458486 RMI1 RecQ mediated genome instability 1 2 10
MIRT458662 PAGR1 PAXIP1 associated glutamate rich protein 1 2 12
MIRT459784 IDH3A isocitrate dehydrogenase 3 (NAD(+)) alpha 2 2
MIRT459864 SVOP SV2 related protein 2 2
MIRT460575 FEM1A fem-1 homolog A 2 2
MIRT460987 STK17B serine/threonine kinase 17b 2 2
MIRT462315 TMEM109 transmembrane protein 109 2 2
MIRT464407 URM1 ubiquitin related modifier 1 2 2
MIRT465148 TSC22D2 TSC22 domain family member 2 2 2
MIRT466312 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466718 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT468258 SFXN4 sideroflexin 4 2 2
MIRT469140 RNF126 ring finger protein 126 2 2
MIRT471783 NUP153 nucleoporin 153 2 2
MIRT472506 NACC2 NACC family member 2 2 2
MIRT474588 KLF6 Kruppel like factor 6 2 2
MIRT475049 JOSD1 Josephin domain containing 1 2 2
MIRT476900 FBXO21 F-box protein 21 2 2
MIRT476972 FAM83G family with sequence similarity 83 member G 2 4
MIRT477433 EMP1 epithelial membrane protein 1 2 2
MIRT480334 C5orf51 chromosome 5 open reading frame 51 2 10
MIRT481179 AVL9 AVL9 cell migration associated 2 6
MIRT481693 AR androgen receptor 2 2
MIRT483280 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 4
MIRT485775 B4GALT5 beta-1,4-galactosyltransferase 5 2 2
MIRT487424 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT488002 RXRB retinoid X receptor beta 2 2
MIRT488259 DNLZ DNL-type zinc finger 2 4
MIRT490360 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT491593 USB1 U6 snRNA biogenesis phosphodiesterase 1 2 2
MIRT495269 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 4
MIRT495619 ZNF736 zinc finger protein 736 2 2
MIRT496167 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT496250 GJB2 gap junction protein beta 2 2 2
MIRT496915 RTKN rhotekin 2 2
MIRT498713 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 10
MIRT501106 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501831 NCOA3 nuclear receptor coactivator 3 2 2
MIRT507142 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT510991 PER1 period circadian clock 1 2 4
MIRT512283 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT513152 CSDC2 cold shock domain containing C2 2 2
MIRT513327 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 6
MIRT515090 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT516113 OARD1 O-acyl-ADP-ribose deacylase 1 2 8
MIRT516657 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT516892 PLEKHS1 pleckstrin homology domain containing S1 2 2
MIRT517966 ZMIZ2 zinc finger MIZ-type containing 2 2 4
MIRT519492 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT519799 ZNF226 zinc finger protein 226 2 2
MIRT524309 CTC1 CST telomere replication complex component 1 2 8
MIRT524425 CNKSR3 CNKSR family member 3 2 2
MIRT525927 KIAA0391 KIAA0391 2 2
MIRT528022 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT528227 METTL8 methyltransferase like 8 2 2
MIRT528686 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT528774 CD1D CD1d molecule 2 2
MIRT529935 P2RX7 purinergic receptor P2X 7 2 2
MIRT530642 PPIC peptidylprolyl isomerase C 2 4
MIRT530683 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT531922 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT532181 SEC14L5 SEC14 like lipid binding 5 2 4
MIRT534996 PRR11 proline rich 11 2 6
MIRT535452 PDCL phosducin like 2 4
MIRT544682 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT553757 TARBP2 TARBP2, RISC loading complex RNA binding subunit 2 4
MIRT560724 ZNF749 zinc finger protein 749 2 2
MIRT561518 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT561578 SLC30A1 solute carrier family 30 member 1 2 2
MIRT562483 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT565039 VAV2 vav guanine nucleotide exchange factor 2 2 2
MIRT565348 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT567104 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT568879 LY6H lymphocyte antigen 6 family member H 2 2
MIRT569141 NAP1L4 nucleosome assembly protein 1 like 4 2 2
MIRT569199 LRRC3C leucine rich repeat containing 3C 2 2
MIRT573559 TMEM120B transmembrane protein 120B 2 2
MIRT575931 Mrrf mitochondrial ribosome recycling factor 2 6
MIRT607035 MRRF mitochondrial ribosome recycling factor 2 9
MIRT607194 SPRY4 sprouty RTK signaling antagonist 4 2 2
MIRT609682 TMEM213 transmembrane protein 213 2 2
MIRT611227 ZNF274 zinc finger protein 274 2 2
MIRT611370 PLXDC1 plexin domain containing 1 2 4
MIRT611640 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT613011 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT613532 GTSE1 G2 and S-phase expressed 1 2 2
MIRT614459 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT616492 CD300E CD300e molecule 2 2
MIRT617288 GTF2H3 general transcription factor IIH subunit 3 2 2
MIRT618356 CDKL1 cyclin dependent kinase like 1 2 2
MIRT619529 ZNF74 zinc finger protein 74 2 2
MIRT619990 ZSCAN22 zinc finger and SCAN domain containing 22 2 2
MIRT621286 ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 2 2
MIRT621482 GPKOW G-patch domain and KOW motifs 2 2
MIRT625456 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT626757 NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 2 2
MIRT629138 CTCFL CCCTC-binding factor like 2 2
MIRT630092 DCAF10 DDB1 and CUL4 associated factor 10 2 2
MIRT633501 RNF14 ring finger protein 14 2 2
MIRT633604 APCDD1 APC down-regulated 1 2 2
MIRT633772 F2 coagulation factor II, thrombin 2 2
MIRT635605 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT637422 EPB41L3 erythrocyte membrane protein band 4.1 like 3 2 2
MIRT637822 PLA2G7 phospholipase A2 group VII 2 2
MIRT637978 RRP36 ribosomal RNA processing 36 2 2
MIRT638385 RABL3 RAB, member of RAS oncogene family like 3 2 2
MIRT638547 KIAA1549 KIAA1549 2 2
MIRT642019 NCKIPSD NCK interacting protein with SH3 domain 2 2
MIRT643342 MICA MHC class I polypeptide-related sequence A 2 2
MIRT644281 LRRC57 leucine rich repeat containing 57 2 2
MIRT646818 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT646839 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT646976 CYP2W1 cytochrome P450 family 2 subfamily W member 1 2 2
MIRT647735 CXCR2 C-X-C motif chemokine receptor 2 2 2
MIRT648598 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT649843 LIPG lipase G, endothelial type 2 2
MIRT650031 VHL von Hippel-Lindau tumor suppressor 2 2
MIRT652082 TSPAN14 tetraspanin 14 2 2
MIRT652103 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT652902 SYNPO2L synaptopodin 2 like 2 2
MIRT653549 SLC38A7 solute carrier family 38 member 7 2 2
MIRT653981 SEMA6B semaphorin 6B 2 2
MIRT654287 RCAN1 regulator of calcineurin 1 2 2
MIRT658372 FAM63B MINDY lysine 48 deubiquitinase 2 2 2
MIRT660321 BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2 2
MIRT663063 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT663269 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 2 2
MIRT664076 ZNF417 zinc finger protein 417 2 2
MIRT664193 MYOZ2 myozenin 2 2 2
MIRT664512 POLR3K RNA polymerase III subunit K 2 2
MIRT667025 PDF peptide deformylase, mitochondrial 2 2
MIRT669621 ACSL6 acyl-CoA synthetase long chain family member 6 2 2
MIRT670530 MLLT6 MLLT6, PHD finger containing 2 2
MIRT673050 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT683339 ZNF581 zinc finger protein 581 2 2
MIRT689264 WDR83OS WD repeat domain 83 opposite strand 2 2
MIRT690902 TOP2A DNA topoisomerase II alpha 2 2
MIRT699196 SLX4IP SLX4 interacting protein 2 2
MIRT702223 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT707053 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT707080 MED29 mediator complex subunit 29 2 2
MIRT712347 NLN neurolysin 2 2
MIRT714715 KIT KIT proto-oncogene receptor tyrosine kinase 2 2
MIRT715963 CES4A carboxylesterase 4A 2 2
MIRT718224 DEFB105B defensin beta 105B 2 2
MIRT718244 DEFB105A defensin beta 105A 2 2
MIRT721960 GCK glucokinase 2 2
MIRT723098 SERINC3 serine incorporator 3 2 2
MIRT725207 PTPRT protein tyrosine phosphatase, receptor type T 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4524b Tripterygium wilfordii Hook F resistant tissue
hsa-miR-4524b-3p Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)

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