miRTarBase - #MIRT447215


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pre-miRNA Information
pre-miRNA hsa-mir-452   
Genomic Coordinates chrX: 151959628 - 151959712
Synonyms MIRN452, hsa-mir-452, MIR452
Description Homo sapiens miR-452 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-452-3p
Sequence 58| CUCAUCUGCAAAGAAGUAAGUG |79
Evidence Experimental
Experiments Array-cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 12 X - 151959644 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs757928550 3 dbSNP
rs1324216965 6 dbSNP
rs1390793899 13 dbSNP
rs899383242 17 dbSNP
rs747858567 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ATXN7   
Synonyms ADCAII, OPCA3, SCA7
Description ataxin 7
Transcript NM_000333   
Other Transcripts NM_001128149 , NM_001177387   
Expression
Putative miRNA Targets on ATXN7
3'UTR of ATXN7
(miRNA target sites are highlighted)		 
>ATXN7|NM_000333|3'UTR
   1 CAGCTGAAAATAGCACGGGGAGGAATAATGCGGACACTTTTGAGGACAAGTTACACCTCCACTCAGCACTCTGGACTCCA
  81 CGATGCCTTTGAGTCTGTTTTCCCAACCTCCTGTGGGCCTCAAGGGTAGAAACCTGCCGGGCTGTTGTTTTAACGAGGAT
 161 TTCCCTGAAGCTATGTCTCTAGCAGTGAGTACTCATAAAGGACACTGGATCAAGTTCAGCCACCGAATTGCTTTTATCAG
 241 TGTTAAAGTGGTCTGAACTGCTTGCTACCAATCTGTGAGAAGTTTTTGTTTTTGTTTTGTTTTTTAACTTGCAGTATATC
 321 ACAGAGCCACTCTTCAAGTAGATTGGCTGGGCAAAAGAATGTTTTGGCAAGAGCGTTACTGTAGACCTTTCTCCCTCCTT
 401 CCTTTTACTACCATTTTTTTTTAACACTGTCATCTGTAGGTCACTCTCCAGCAGTTAGGCACCTTAACTGGAGACCAGAA
 481 ACCTTCCAGAGAACACAGGGCTGCATCCCGAGCAACCCTCTGAAGAAGGGAATTAGGCTTTAGATTTTGATAGCAATGTT
 561 CCAGGAATGAAATATAGATGTTAGCCCAAGACACCATGACAAAATAGCCCAGCCTTTTGAGAGTAATTTGGGAAAAGAAG
 641 CTGTCAGAAGTTTCTAACTTACAAACTGGTTTGAAATTTTTGATGCCCAGACAGCAAGTATAAATCATTTTGGAGGCTTA
 721 CTTTTCATGATACAAAAGCAATTCTGTGTGATTTTTTTTTTTAAGAAGAAAGAAAATGCAAGCTAGTTTTGAGAAAGGAA
 801 GGCCAAATTGGGTCGGGGGAGGGTGGGAGTGAGGAAGTTAAAATCACTATAGGGAGAAAAAACTTTTTTCAAGATTTCCA
 881 AAGAGATGAAATTTTCTTAATCCTTTTAAGTTTTCATAGTAAACAGTATGGCAGATTGGGTTGGTTGTCCTACCTGGTCT
 961 ATTTTTAAAAGTCACCTTTTAAAGTGACATTATTAGATACACTTAAATGTTTCCAAGGCACTCTCTACATTACCCTTGTT
1041 TTTCTCTTTGGATACTGTCCTGGGACTAAGTGTAGATTTCTGCTTCAAGCACTTCTGGCATTGTGTGTTTTTGTATGCAC
1121 TCCCCTTCATGCCACTTCAGATGTTTATTTGGATGTGGTTGGGGACGAGAGCAGACACCAAGGAAAGGGAGTTGGAGAGA
1201 ATGTAAGTCCTGACCTGAAGGTCTTTTGTGATGCATGTATAGGATTGCCCTGACACACACCCTCCTTTCTTGGGATTATA
1281 CCAGCCATCTTCCTGAGAGTTTTGGAGCCCTCTAGGATATTTTTTCTAGTACCCCACCCCCCACCCCTAAAGAAAGACCT
1361 TAATATGTTAAAACAGCATTGCTTGGAGAAGGTGTCATTGAATTCCGGGACGAGCCGGAGCCTTTAAATGGGTGCTTCCA
1441 CCACTACAGGCTCCTGACACGAGTAACAGGCACTGTTGCTTAGAAGAACACACGAAGTTGCCGAACACAGGGTAAAATTT
1521 CCAAGGCGCTGATCGTTGCCCTGGCCAGGGCCTGATGAGAGCCAGTCAGTACATTCTTTTTTTCCTACAGTTCTTGGGTT
1601 TCAAACTTCAGTTTCAGGGAATTTCAAGTCAACAACAGGTAGAATGAATAAACTTGGTTACCAGCCTAATAATGTGAATT
1681 GCTACAGAATTATTCTTATTATGTAAGAAAACAAAAACTTTATGCAGATACTTTAGCTATAAATTGATGTAAAATACTGA
1761 TTTTTTTAAAGGAAGGAGAGAACAGTATCTTGTTCAATTATTATGCAATCAATCAGTAAATGTTTTTAAAATGATACTAC
1841 AGGAGAGCTTAGTAAGGAGAGGGCATGGATGGGCCAGTTTGGCATAGTTGGGAGAAATCAGTCTGGTTTCCATCCCAGTC
1921 GGGGAAGAGAGAGGTGAGAGGGAATCAGAACGTACCTAGTTGATTCCTTGGTGACAAGTGCAATGGGGTATGGGTAGAAT
2001 TTATTTTCAGAGCCAAGAGGACTTGATGGTTATAAATAAAGTTGCCTTTAGCAATGGAATTTACAGATCGATCATGTTGT
2081 TCCGAAAGATGTGAATAGGATCCACAATAACAAGTTGATTCAGACTAATGTAGATATTTAGATTAGCAAGTATTGAACAT
2161 TTGATTTCTTAGACTGAGGTTTTAAATGAATTTCATTATTTCTCCCGGTAATACACAGAGCATCGGGATTAGGAAATTAG
2241 CCATTTTGGATTCTGTCTGCCACAAACAGACCTATTCTAAACAGTGCTATTAAATTTTAGACTGTTGTTCAAATATTTTA
2321 TTTTCTCCTAAACTACTTTTTATGGTGATGAATAATTAAGACCATTTAAAACACGGGAGTACAAGTATTTTTTTGAATTA
2401 AATTAACTTGCAAAAACCAAATTTGCAGTGGTTGGGTTGTTTCTAGACAGACTTTGGTATCAATTTAAAACCAAGATAAT
2481 TTTTATATTCTTTCCAATAGAATTTCATGACAACTCCTGCAGTTTTCTTAACCTACAAAAAAAAAAAAAAAGTGCTGCAA
2561 TGATGAACAAAGAATTATACAAAACCTACTTTTGTATCTTTATTTTGGAATTTCTTGTTCTATTATAAATATGGAAGTAT
2641 CCCTATTTCAGAAGACATATTTTGTTAAAAATGAATTGTACATATTTAAATATGTATTTTTGCACAGGTCTTTTTTTCTG
2721 ATATCCTGTTTTGGTACAATTGAGATCATCTAGTATTTATTTATTAATTAATAAAAGTAAATACCTTTTTATAATTTGAA
2801 GTGGTTCACTGCCAAGCCAATAGTTCTAGAACCTGCCTCCTTTACAGTTTTAAGGGATGCCTCTGTTCTGTGAAAAGTCT
2881 TTGTCCCTTTTAGTGTCTCGGGAGTGGATTCATACAGATGAAGTGGGCATTGCTTCTTCCTGGTTGCCTGGTTTCCCGAT
2961 AGACTACATGTAACTAAGTGACACACTGCTTTTCTTTTGTTAGTATTTTATGTGTGGGAGTATGTGACTGCGTGTGTGTG
3041 TGCCTGTGCGTGTGTGTGTATACTCAGCACATGTATGTTACTATGTGATGTGGTTTAAAACTAATGGAAAAAACTGAAAG
3121 TGCCTGAAACTAGTTTTAAGCTTAGACAGAATCTCTTTAAAAAGACTTGAATGTTCAGTTGAACTTTTGGAGTTTGCTTT
3201 TTCCACCTAAATATTGTTTCTAAAATTTTAGGGGCGGAGTTGAAAACCACCAATGCTGGTAATTTTATAAGGTATTTTAA
3281 AATTAAGACCTCTTGGTTCATAGTAATTCAATTGGTGATGGATTGCCTGGTGGCACCAAGGGTTACAGATCTTTTTGTCA
3361 GCCAGCAACTTACACGATGTGTCCGTTTTGTTATTCACTCATGAAATACAATTTAAAATATTTAAAATATTTTGTATTCC
3441 AAAAATATAATACAAAGAAGTACCTCTGAGAACATTGAAAAAAATGTATAATTTGAAAAATGTAACTTATAAGGGCAGCT
3521 GTCTTCCTGCAAGAGTTCTGTTGCCAAGGAATTTCTTAATGTCGCTCATTCTGTCCAGGGGGTTTGGGGCGATTGGGCTT
3601 TGAAAAAATATTCTTAAAAGTTTGTTTAGCAGAAAATAATCACTTTTACATTTTGTGCAAAACATTTTACATTTTCAGAT
3681 AATTTAAATGAGCACTACATACTGTCAGTGTGAATGTAGGGCCTTGAAAGCATTTTGCTTTTTTTTTTTTTTTTTTTTTT
3761 TTGAGCTTGGTTATAAAAGCAATCTCCTGTGTTAAAAACGTGTGAATAGTTTGATAATTTGTACACATAATCAAGAGCAT
3841 CTCAGCTGGACTTTGTGTTGGCTGCTGTATAGAACATGAACAAATGTCAAGGGATAGAAAATTACTTTGGATATTTAAAA
3921 GAGAAGAAATATATAGTCTATTTGTTTTGTAACAAGTTTCTGTAAATAAAATAATTTATACTATTTATAAGAAAAAAAAA
4001 AAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gugaaugAAGAAACGUCUACUc 5'
                 |||  | ||||||| 
Target 5' gagtggaTTC-ATACAGATGAa 3'
 2902 - 2922 146.00 -8.10
2 
miRNA  3' guGAAUGAAGAAACGUCUACuc 5'
            | |:|  |||  ||||||  
Target 5' ttCATGCCACTT--CAGATGtt 3'
 1126 - 1145 132.00 -8.70
3 
miRNA  3' gugaaUGAAGAAACGUCUAcuc 5'
               |||| | |||||||   
Target 5' caaaaACTT-TATGCAGATact 3'
 1712 - 1732 124.00 -8.62
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
599471 15 ClinVar
809503 32 ClinVar
COSM1425063 4 COSMIC
COSM308357 15 COSMIC
COSM3380679 17 COSMIC
COSM8625185 17 COSMIC
COSM6586445 30 COSMIC
COSM1184237 80 COSMIC
COSM8640503 92 COSMIC
COSN19673960 97 COSMIC
COSN31590359 138 COSMIC
COSN19766042 178 COSMIC
COSN29543736 808 COSMIC
COSN23117452 815 COSMIC
COSN26505039 816 COSMIC
COSN31486969 857 COSMIC
COSN31962083 874 COSMIC
COSN31480592 879 COSMIC
COSN30159577 923 COSMIC
COSN19058996 970 COSMIC
COSN31590803 1024 COSMIC
COSN31521657 1056 COSMIC
COSN18946125 1170 COSMIC
COSN229039 1372 COSMIC
COSN15902211 1697 COSMIC
COSN1956980 2120 COSMIC
COSN23050204 2125 COSMIC
COSN6574929 2317 COSMIC
COSN7704187 2331 COSMIC
COSN31563002 2522 COSMIC
COSN28930142 2552 COSMIC
COSN26549140 2595 COSMIC
COSN26639929 2634 COSMIC
COSN31482273 2751 COSMIC
COSN31538699 2958 COSMIC
COSN20090831 2970 COSMIC
COSN25295651 3698 COSMIC
COSN28201029 3752 COSMIC
COSN9557260 3815 COSMIC
COSN25291680 3918 COSMIC
COSN25294534 3920 COSMIC
COSN25291681 3923 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs751048443 10 dbSNP
rs1275131150 13 dbSNP
rs180696871 15 dbSNP
rs1273743537 16 dbSNP
rs1211731978 17 dbSNP
rs1389085494 17 dbSNP
rs780787335 18 dbSNP
rs745466231 19 dbSNP
rs769503307 23 dbSNP
rs1278979431 26 dbSNP
rs780212405 30 dbSNP
rs749733097 31 dbSNP
rs769269406 32 dbSNP
rs748272621 33 dbSNP
rs1473967548 34 dbSNP
rs761951339 37 dbSNP
rs772003452 41 dbSNP
rs1463807995 54 dbSNP
rs933924549 57 dbSNP
rs773364173 60 dbSNP
rs1395958753 65 dbSNP
rs756509918 69 dbSNP
rs778802006 71 dbSNP
rs1295413471 73 dbSNP
rs1307940358 78 dbSNP
rs1353623947 79 dbSNP
rs1232796857 80 dbSNP
rs760750156 82 dbSNP
rs752476125 83 dbSNP
rs762787169 85 dbSNP
rs904090659 86 dbSNP
rs201478726 87 dbSNP
rs751461369 90 dbSNP
rs748109169 92 dbSNP
rs943434782 92 dbSNP
rs899286796 93 dbSNP
rs994959421 94 dbSNP
rs757243736 107 dbSNP
rs780514689 108 dbSNP
rs1209105595 109 dbSNP
rs1186630483 111 dbSNP
rs1420776107 117 dbSNP
rs1430815524 118 dbSNP
rs749950312 119 dbSNP
rs753946408 120 dbSNP
rs755713008 120 dbSNP
rs1372854442 123 dbSNP
rs779908613 125 dbSNP
rs749645247 127 dbSNP
rs1003807539 132 dbSNP
rs769181398 134 dbSNP
rs1303822720 135 dbSNP
rs1031690166 137 dbSNP
rs1357659798 139 dbSNP
rs762254732 139 dbSNP
rs779450176 139 dbSNP
rs528224210 140 dbSNP
rs1156922209 142 dbSNP
rs765791311 143 dbSNP
rs546603553 155 dbSNP
rs771725606 156 dbSNP
rs1014179976 158 dbSNP
rs1482144403 159 dbSNP
rs1420592666 165 dbSNP
rs184480137 166 dbSNP
rs77203794 174 dbSNP
rs879571540 178 dbSNP
rs73834169 182 dbSNP
rs1246300242 191 dbSNP
rs1324035235 193 dbSNP
rs1313992445 201 dbSNP
rs1370367295 206 dbSNP
rs1026973650 214 dbSNP
rs1385554179 215 dbSNP
rs1436063498 215 dbSNP
rs1318660730 225 dbSNP
rs1459453470 226 dbSNP
rs952731553 232 dbSNP
rs867814278 233 dbSNP
rs1391760189 236 dbSNP
rs911155795 237 dbSNP
rs189447000 239 dbSNP
rs982680059 248 dbSNP
rs943362652 254 dbSNP
rs908460595 259 dbSNP
rs879053579 264 dbSNP
rs1245748853 272 dbSNP
rs537239991 274 dbSNP
rs965232187 276 dbSNP
rs1211127243 282 dbSNP
rs1266617565 284 dbSNP
rs1488514368 284 dbSNP
rs1240476647 285 dbSNP
rs557741706 290 dbSNP
rs1300296229 292 dbSNP
rs1351308505 293 dbSNP
rs1215649900 295 dbSNP
rs1364743765 295 dbSNP
rs1293680450 296 dbSNP
rs1388660823 298 dbSNP
rs759317342 300 dbSNP
rs537003212 303 dbSNP
rs181414756 312 dbSNP
rs1372285284 321 dbSNP
rs1168994125 322 dbSNP
rs1428800156 323 dbSNP
rs1039045588 330 dbSNP
rs1200546521 335 dbSNP
rs541092375 335 dbSNP
rs1489443161 339 dbSNP
rs1188902587 343 dbSNP
rs1490013153 344 dbSNP
rs1189351878 367 dbSNP
rs930733058 369 dbSNP
rs1206386334 371 dbSNP
rs1048328600 373 dbSNP
rs920995803 374 dbSNP
rs1440390192 376 dbSNP
rs1180806490 381 dbSNP
rs567404509 388 dbSNP
rs1378708756 394 dbSNP
rs1331848892 398 dbSNP
rs114899708 403 dbSNP
rs552918625 411 dbSNP
rs1352270164 413 dbSNP
rs1056705433 414 dbSNP
rs1394031802 414 dbSNP
rs1409058084 414 dbSNP
rs3836529 414 dbSNP
rs1174019508 449 dbSNP
rs868336868 456 dbSNP
rs1165964169 457 dbSNP
rs1011914966 463 dbSNP
rs1173356509 468 dbSNP
rs577962164 477 dbSNP
rs1183488498 479 dbSNP
rs1254673950 479 dbSNP
rs934319179 484 dbSNP
rs369620380 495 dbSNP
rs1248886133 497 dbSNP
rs967754958 501 dbSNP
rs1345980821 508 dbSNP
rs538884771 510 dbSNP
rs556965841 511 dbSNP
rs1446867552 515 dbSNP
rs1047026665 516 dbSNP
rs1409113906 517 dbSNP
rs905274929 522 dbSNP
rs115253214 525 dbSNP
rs1313190617 529 dbSNP
rs1396330881 533 dbSNP
rs1401075284 536 dbSNP
rs1323251939 543 dbSNP
rs1334276775 550 dbSNP
rs987069841 554 dbSNP
rs1027027731 556 dbSNP
rs952677672 557 dbSNP
rs1472568562 558 dbSNP
rs1004653683 562 dbSNP
rs1443339894 562 dbSNP
rs575582720 565 dbSNP
rs542823138 571 dbSNP
rs965698774 575 dbSNP
rs186686373 576 dbSNP
rs1268875665 580 dbSNP
rs1227822037 585 dbSNP
rs983537019 595 dbSNP
rs190745990 597 dbSNP
rs1285826855 599 dbSNP
rs953878505 613 dbSNP
rs759197372 614 dbSNP
rs1057073382 619 dbSNP
rs1436857052 620 dbSNP
rs925702264 624 dbSNP
rs948290360 627 dbSNP
rs1398391367 628 dbSNP
rs934337856 629 dbSNP
rs1164767569 633 dbSNP
rs770604131 634 dbSNP
rs1384979154 637 dbSNP
rs148551198 639 dbSNP
rs1332833435 641 dbSNP
rs1030739448 644 dbSNP
rs1445344607 647 dbSNP
rs564854307 650 dbSNP
rs556062388 657 dbSNP
rs562804861 659 dbSNP
rs530263312 663 dbSNP
rs1002333147 674 dbSNP
rs563826186 675 dbSNP
rs1230255582 677 dbSNP
rs1048454276 679 dbSNP
rs1226407717 683 dbSNP
rs1018528480 687 dbSNP
rs1332287963 690 dbSNP
rs1326172506 691 dbSNP
rs1179509215 692 dbSNP
rs1318554318 702 dbSNP
rs888568799 707 dbSNP
rs963896767 709 dbSNP
rs1365465213 717 dbSNP
rs973974819 717 dbSNP
rs531268571 721 dbSNP
rs1016037962 722 dbSNP
rs901186589 727 dbSNP
rs1256290222 734 dbSNP
rs1391084504 734 dbSNP
rs998486481 750 dbSNP
rs1186146581 751 dbSNP
rs112759850 752 dbSNP
rs1474493657 752 dbSNP
rs532905732 752 dbSNP
rs564179420 752 dbSNP
rs952032814 752 dbSNP
rs549130161 756 dbSNP
rs953825601 758 dbSNP
rs1342601181 763 dbSNP
rs142980121 765 dbSNP
rs1212416349 766 dbSNP
rs1346623946 772 dbSNP
rs983891318 786 dbSNP
rs1435047387 787 dbSNP
rs1345453277 810 dbSNP
rs771024428 815 dbSNP
rs1482366566 816 dbSNP
rs1371531012 821 dbSNP
rs1170124007 822 dbSNP
rs1181648463 824 dbSNP
rs1408460067 826 dbSNP
rs575897203 827 dbSNP
rs1427445411 840 dbSNP
rs1264304201 850 dbSNP
rs151104593 852 dbSNP
rs571752248 854 dbSNP
rs181913082 860 dbSNP
rs1184217765 861 dbSNP
rs1483288676 864 dbSNP
rs1232114409 865 dbSNP
rs557353948 866 dbSNP
rs916761587 867 dbSNP
rs1278822268 873 dbSNP
rs1218194106 876 dbSNP
rs1320797420 880 dbSNP
rs1281978274 884 dbSNP
rs948260644 887 dbSNP
rs1351594817 888 dbSNP
rs1297966863 889 dbSNP
rs1043983710 891 dbSNP
rs1440395534 894 dbSNP
rs1361176174 895 dbSNP
rs3836530 904 dbSNP
rs397841163 904 dbSNP
rs988482828 904 dbSNP
rs200800677 905 dbSNP
rs1469389950 910 dbSNP
rs935007459 922 dbSNP
rs186560191 928 dbSNP
rs560428028 935 dbSNP
rs758846211 936 dbSNP
rs1401809759 938 dbSNP
rs1175282334 939 dbSNP
rs1008401155 940 dbSNP
rs1202610411 941 dbSNP
rs1276224377 943 dbSNP
rs949767892 945 dbSNP
rs982293327 948 dbSNP
rs1318060069 955 dbSNP
rs536565923 957 dbSNP
rs1222488923 958 dbSNP
rs926909057 962 dbSNP
rs938177690 974 dbSNP
rs899695783 985 dbSNP
rs995327302 986 dbSNP
rs1280745703 987 dbSNP
rs1164546939 988 dbSNP
rs751483443 1001 dbSNP
rs888525232 1003 dbSNP
rs1210384211 1005 dbSNP
rs1264410805 1019 dbSNP
rs191077593 1021 dbSNP
rs1192193646 1022 dbSNP
rs182363490 1023 dbSNP
rs1026850571 1024 dbSNP
rs940070648 1025 dbSNP
rs1156836269 1026 dbSNP
rs1425380302 1027 dbSNP
rs13272 1028 dbSNP
rs1182703564 1029 dbSNP
rs1191296089 1036 dbSNP
rs573080384 1037 dbSNP
rs751865993 1047 dbSNP
rs901131144 1047 dbSNP
rs1249437249 1049 dbSNP
rs1004846339 1052 dbSNP
rs1485255814 1057 dbSNP
rs1015345261 1060 dbSNP
rs998205708 1066 dbSNP
rs1214246071 1072 dbSNP
rs1028237762 1078 dbSNP
rs1412453011 1079 dbSNP
rs1172592716 1081 dbSNP
rs1361003356 1083 dbSNP
rs1421276920 1085 dbSNP
rs1296055938 1087 dbSNP
rs889748280 1089 dbSNP
rs1437060164 1091 dbSNP
rs1276716625 1094 dbSNP
rs1365552629 1096 dbSNP
rs1233899552 1097 dbSNP
rs1380881408 1097 dbSNP
rs752287584 1102 dbSNP
rs992669061 1102 dbSNP
rs1356049468 1105 dbSNP
rs1214905362 1106 dbSNP
rs540293087 1110 dbSNP
rs1361350146 1115 dbSNP
rs1287099773 1120 dbSNP
rs1000014035 1122 dbSNP
rs544839190 1125 dbSNP
rs1459388668 1154 dbSNP
rs558361550 1160 dbSNP
rs916691456 1164 dbSNP
rs1162724371 1167 dbSNP
rs1283950700 1168 dbSNP
rs1391676881 1177 dbSNP
rs1452714596 1177 dbSNP
rs1427469966 1191 dbSNP
rs969534127 1202 dbSNP
rs767338049 1204 dbSNP
rs925525395 1204 dbSNP
rs1452027438 1208 dbSNP
rs935585063 1215 dbSNP
rs1192685376 1218 dbSNP
rs1277116915 1227 dbSNP
rs368937006 1228 dbSNP
rs576920309 1231 dbSNP
rs1228408128 1234 dbSNP
rs543844162 1236 dbSNP
rs1293567869 1237 dbSNP
rs867688097 1243 dbSNP
rs1441085937 1244 dbSNP
rs943780574 1250 dbSNP
rs11922969 1251 dbSNP
rs1039414653 1253 dbSNP
rs1405937133 1255 dbSNP
rs562517122 1259 dbSNP
rs995297716 1260 dbSNP
rs1348283308 1261 dbSNP
rs1168930455 1265 dbSNP
rs1461176879 1273 dbSNP
rs1440275547 1279 dbSNP
rs1370944815 1280 dbSNP
rs988945354 1301 dbSNP
rs1433238615 1303 dbSNP
rs1430660508 1309 dbSNP
rs1309982807 1323 dbSNP
rs780971911 1326 dbSNP
rs1048218638 1329 dbSNP
rs1254430107 1330 dbSNP
rs1196711154 1335 dbSNP
rs1480444444 1337 dbSNP
rs1379429738 1338 dbSNP
rs1024064186 1339 dbSNP
rs1235566849 1342 dbSNP
rs1238177810 1343 dbSNP
rs1279388014 1344 dbSNP
rs1357459591 1345 dbSNP
rs1212219454 1346 dbSNP
rs1390554923 1353 dbSNP
rs971461240 1364 dbSNP
rs1304188548 1366 dbSNP
rs1469925666 1367 dbSNP
rs1427969726 1371 dbSNP
rs552349200 1372 dbSNP
rs1479743210 1373 dbSNP
rs1414776372 1376 dbSNP
rs1004548520 1384 dbSNP
rs1183051326 1387 dbSNP
rs187957148 1399 dbSNP
rs1238212372 1408 dbSNP
rs938294287 1412 dbSNP
rs984349017 1413 dbSNP
rs1280043935 1415 dbSNP
rs910017337 1417 dbSNP
rs755202728 1418 dbSNP
rs191044528 1421 dbSNP
rs922744676 1429 dbSNP
rs528652831 1435 dbSNP
rs1411536201 1446 dbSNP
rs1387829542 1447 dbSNP
rs1159651033 1454 dbSNP
rs1453573108 1455 dbSNP
rs969502986 1460 dbSNP
rs1189969591 1462 dbSNP
rs1445502881 1464 dbSNP
rs547217123 1476 dbSNP
rs1466284077 1482 dbSNP
rs956950241 1486 dbSNP
rs988817824 1490 dbSNP
rs912838457 1494 dbSNP
rs1332149305 1495 dbSNP
rs943693836 1502 dbSNP
rs570828438 1504 dbSNP
rs1039383080 1508 dbSNP
rs1312426119 1509 dbSNP
rs769377701 1509 dbSNP
rs1436735049 1513 dbSNP
rs1326496149 1515 dbSNP
rs1316950209 1517 dbSNP
rs539940809 1521 dbSNP
rs1054399947 1524 dbSNP
rs1444892008 1526 dbSNP
rs531711308 1529 dbSNP
rs1425663922 1530 dbSNP
rs1384890325 1535 dbSNP
rs748378792 1536 dbSNP
rs1010102745 1537 dbSNP
rs558469362 1539 dbSNP
rs971192713 1540 dbSNP
rs1192473365 1545 dbSNP
rs183418963 1546 dbSNP
rs1247463260 1564 dbSNP
rs1282719308 1570 dbSNP
rs1223007193 1572 dbSNP
rs1334803022 1574 dbSNP
rs1219734623 1577 dbSNP
rs1230180661 1577 dbSNP
rs115550453 1589 dbSNP
rs1319348589 1597 dbSNP
rs1193788897 1615 dbSNP
rs1269111448 1622 dbSNP
rs1249369966 1625 dbSNP
rs1427982325 1628 dbSNP
rs1325249857 1630 dbSNP
rs1305458162 1631 dbSNP
rs1406004792 1634 dbSNP
rs1442566808 1639 dbSNP
rs1057414971 1640 dbSNP
rs1189394402 1645 dbSNP
rs1255073427 1647 dbSNP
rs1411869242 1650 dbSNP
rs895768920 1653 dbSNP
rs1167427459 1662 dbSNP
rs951732765 1668 dbSNP
rs1013591653 1680 dbSNP
rs1023646687 1686 dbSNP
rs1200047188 1689 dbSNP
rs1171259876 1690 dbSNP
rs1490150274 1690 dbSNP
rs139145114 1696 dbSNP
rs1460517549 1700 dbSNP
rs1167347459 1703 dbSNP
rs1403187700 1704 dbSNP
rs1438070354 1715 dbSNP
rs1000963868 1719 dbSNP
rs1397966589 1722 dbSNP
rs1032488982 1728 dbSNP
rs1346500880 1729 dbSNP
rs201027399 1732 dbSNP
rs764674434 1732 dbSNP
rs777889897 1737 dbSNP
rs1224673211 1740 dbSNP
rs988359846 1748 dbSNP
rs1020282532 1749 dbSNP
rs34471608 1751 dbSNP
rs554914439 1754 dbSNP
rs910143001 1759 dbSNP
rs965603448 1761 dbSNP
rs975015435 1761 dbSNP
rs187302239 1764 dbSNP
rs533975414 1768 dbSNP
rs1354662346 1774 dbSNP
rs1401191176 1774 dbSNP
rs1408410899 1774 dbSNP
rs1480088267 1781 dbSNP
rs1427056356 1784 dbSNP
rs961836653 1788 dbSNP
rs1341900227 1789 dbSNP
rs747548769 1798 dbSNP
rs1470371521 1805 dbSNP
rs1201986747 1806 dbSNP
rs771384084 1806 dbSNP
rs1250222016 1809 dbSNP
rs1345304732 1812 dbSNP
rs1202438296 1817 dbSNP
rs931038378 1821 dbSNP
rs777032870 1825 dbSNP
rs1281901595 1832 dbSNP
rs1225903880 1837 dbSNP
rs1201791298 1842 dbSNP
rs1374498777 1843 dbSNP
rs1279281697 1848 dbSNP
rs1049854666 1852 dbSNP
rs1485218833 1857 dbSNP
rs1337498705 1858 dbSNP
rs1469336562 1864 dbSNP
rs1403870622 1870 dbSNP
rs192294510 1870 dbSNP
rs79896076 1871 dbSNP
rs143984857 1873 dbSNP
rs555836975 1876 dbSNP
rs1406993422 1885 dbSNP
rs574104223 1889 dbSNP
rs770314056 1895 dbSNP
rs1243320457 1898 dbSNP
rs1182494174 1900 dbSNP
rs1192601712 1904 dbSNP
rs1459563803 1916 dbSNP
rs1254825665 1918 dbSNP
rs895686599 1920 dbSNP
rs775215267 1922 dbSNP
rs1284047787 1923 dbSNP
rs1467819673 1926 dbSNP
rs1238370820 1927 dbSNP
rs1045059158 1930 dbSNP
rs1315959458 1932 dbSNP
rs905213487 1952 dbSNP
rs1375296266 1954 dbSNP
rs762706967 1956 dbSNP
rs1431394735 1958 dbSNP
rs1344490931 1964 dbSNP
rs76350727 1967 dbSNP
rs558239897 1968 dbSNP
rs1300378268 1976 dbSNP
rs892589506 1979 dbSNP
rs1385517032 1982 dbSNP
rs561241983 1984 dbSNP
rs1010109689 1991 dbSNP
rs1263228794 1994 dbSNP
rs763681624 1997 dbSNP
rs1382103749 2003 dbSNP
rs878946899 2014 dbSNP
rs1486493153 2015 dbSNP
rs1242023662 2017 dbSNP
rs1378264640 2024 dbSNP
rs1362036631 2029 dbSNP
rs1294288829 2032 dbSNP
rs1245534059 2051 dbSNP
rs1010465265 2055 dbSNP
rs184678476 2070 dbSNP
rs1019787343 2071 dbSNP
rs528786861 2073 dbSNP
rs965571477 2074 dbSNP
rs1406611126 2075 dbSNP
rs975652770 2077 dbSNP
rs1028554049 2084 dbSNP
rs907057481 2085 dbSNP
rs1346631201 2086 dbSNP
rs983836115 2090 dbSNP
rs1217070094 2092 dbSNP
rs908287587 2095 dbSNP
rs1419512740 2096 dbSNP
rs1001215902 2107 dbSNP
rs1034064285 2108 dbSNP
rs1287843440 2116 dbSNP
rs951681272 2126 dbSNP
rs1490966830 2132 dbSNP
rs1270056763 2136 dbSNP
rs1222161923 2138 dbSNP
rs1487639070 2150 dbSNP
rs1484865975 2155 dbSNP
rs767714521 2157 dbSNP
rs1204461484 2164 dbSNP
rs540455579 2165 dbSNP
rs1276325413 2169 dbSNP
rs939790251 2178 dbSNP
rs1268197847 2179 dbSNP
rs1346029667 2180 dbSNP
rs1005920341 2185 dbSNP
rs1434979919 2192 dbSNP
rs917103854 2195 dbSNP
rs1298392794 2199 dbSNP
rs1461097903 2205 dbSNP
rs948597736 2207 dbSNP
rs565492381 2208 dbSNP
rs904470836 2213 dbSNP
rs961676729 2217 dbSNP
rs973299690 2223 dbSNP
rs1053792322 2225 dbSNP
rs922767637 2226 dbSNP
rs1196586761 2227 dbSNP
rs1480393691 2238 dbSNP
rs187544052 2244 dbSNP
rs551056959 2245 dbSNP
rs146464987 2247 dbSNP
rs1205591583 2259 dbSNP
rs1324258915 2264 dbSNP
rs1262398866 2269 dbSNP
rs1230880419 2286 dbSNP
rs1337298543 2290 dbSNP
rs1453721805 2291 dbSNP
rs1307369207 2306 dbSNP
rs568349747 2307 dbSNP
rs1009664900 2313 dbSNP
rs1041585799 2319 dbSNP
rs985506244 2326 dbSNP
rs911320179 2327 dbSNP
rs1453120239 2329 dbSNP
rs1407516670 2334 dbSNP
rs761776385 2344 dbSNP
rs1464905967 2346 dbSNP
rs990187597 2357 dbSNP
rs1323226310 2359 dbSNP
rs750782645 2363 dbSNP
rs913126380 2364 dbSNP
rs945954618 2375 dbSNP
rs530110455 2376 dbSNP
rs1242523017 2382 dbSNP
rs1311247850 2383 dbSNP
rs1198676361 2385 dbSNP
rs573364181 2387 dbSNP
rs1352665632 2388 dbSNP
rs1314879293 2389 dbSNP
rs1238328525 2395 dbSNP
rs1351116249 2396 dbSNP
rs140925736 2406 dbSNP
rs1015268115 2408 dbSNP
rs961389257 2412 dbSNP
rs937182986 2414 dbSNP
rs1387716884 2427 dbSNP
rs1265948922 2428 dbSNP
rs992611702 2430 dbSNP
rs1055462644 2436 dbSNP
rs917028353 2437 dbSNP
rs1489392306 2438 dbSNP
rs1165692683 2443 dbSNP
rs887567467 2444 dbSNP
rs1185456669 2448 dbSNP
rs1448684136 2448 dbSNP
rs535677943 2449 dbSNP
rs1014621620 2472 dbSNP
rs1293561911 2480 dbSNP
rs534093934 2494 dbSNP
rs1358239373 2495 dbSNP
rs925819675 2498 dbSNP
rs897498705 2499 dbSNP
rs1228951891 2501 dbSNP
rs994409317 2506 dbSNP
rs1319552550 2508 dbSNP
rs935939927 2514 dbSNP
rs1406321883 2516 dbSNP
rs1418847502 2517 dbSNP
rs1359043608 2520 dbSNP
rs1165856110 2530 dbSNP
rs558438394 2533 dbSNP
rs1198903098 2535 dbSNP
rs1029155770 2537 dbSNP
rs1054165249 2537 dbSNP
rs1192834700 2537 dbSNP
rs1391803071 2537 dbSNP
rs77184837 2537 dbSNP
rs879220831 2537 dbSNP
rs1323335032 2538 dbSNP
rs1393068833 2539 dbSNP
rs1447116001 2551 dbSNP
rs1222892303 2553 dbSNP
rs1029924306 2564 dbSNP
rs1490099280 2576 dbSNP
rs570626308 2589 dbSNP
rs1287270425 2591 dbSNP
rs1197109240 2596 dbSNP
rs1269021289 2597 dbSNP
rs1339459100 2597 dbSNP
rs1218570900 2599 dbSNP
rs1299523361 2610 dbSNP
rs1339035814 2612 dbSNP
rs955493856 2615 dbSNP
rs553930844 2618 dbSNP
rs36035541 2620 dbSNP
rs945393244 2623 dbSNP
rs1274160089 2627 dbSNP
rs1321820717 2638 dbSNP
rs1390622837 2640 dbSNP
rs1018351140 2644 dbSNP
rs957468396 2651 dbSNP
rs79883177 2652 dbSNP
rs990651285 2655 dbSNP
rs901298718 2656 dbSNP
rs1336902666 2672 dbSNP
rs996966270 2675 dbSNP
rs1049887999 2676 dbSNP
rs537500103 2680 dbSNP
rs913207172 2682 dbSNP
rs946040436 2685 dbSNP
rs1005815608 2691 dbSNP
rs1477574675 2692 dbSNP
rs1244680208 2693 dbSNP
rs1318688941 2694 dbSNP
rs1015654644 2695 dbSNP
rs1196153679 2706 dbSNP
rs556214178 2709 dbSNP
rs961057135 2711 dbSNP
rs1265507601 2719 dbSNP
rs774401009 2722 dbSNP
rs541274040 2725 dbSNP
rs969796688 2726 dbSNP
rs979895818 2729 dbSNP
rs1480391835 2732 dbSNP
rs1330824941 2740 dbSNP
rs559260640 2749 dbSNP
rs572145490 2750 dbSNP
rs925787218 2752 dbSNP
rs1177058287 2754 dbSNP
rs957490621 2754 dbSNP
rs1182837150 2759 dbSNP
rs1422806242 2763 dbSNP
rs981346851 2763 dbSNP
rs1160046514 2764 dbSNP
rs540778279 2769 dbSNP
rs574708993 2774 dbSNP
rs1470320041 2775 dbSNP
rs1237165082 2784 dbSNP
rs1258643507 2786 dbSNP
rs1474541602 2793 dbSNP
rs913168904 2794 dbSNP
rs1164798412 2795 dbSNP
rs1211449079 2805 dbSNP
rs1009133429 2814 dbSNP
rs928589622 2818 dbSNP
rs945388060 2821 dbSNP
rs1171836948 2822 dbSNP
rs1352408470 2826 dbSNP
rs937173190 2828 dbSNP
rs1308802149 2837 dbSNP
rs1461140834 2840 dbSNP
rs1041062600 2851 dbSNP
rs1337396061 2864 dbSNP
rs1055577164 2871 dbSNP
rs56783135 2873 dbSNP
rs565694302 2877 dbSNP
rs941762176 2878 dbSNP
rs932747064 2879 dbSNP
rs574239008 2887 dbSNP
rs750393646 2893 dbSNP
rs193273102 2901 dbSNP
rs184160451 2910 dbSNP
rs755821236 2912 dbSNP
rs891405536 2913 dbSNP
rs1007049056 2914 dbSNP
rs1446017712 2925 dbSNP
rs150104842 2927 dbSNP
rs1180729296 2928 dbSNP
rs1483220315 2941 dbSNP
rs1236201786 2942 dbSNP
rs957788611 2943 dbSNP
rs1218470010 2953 dbSNP
rs1037275180 2955 dbSNP
rs540945464 2958 dbSNP
rs1216406156 2959 dbSNP
rs539520330 2961 dbSNP
rs758689490 2963 dbSNP
rs1211059173 2965 dbSNP
rs565290077 2969 dbSNP
rs777801481 2970 dbSNP
rs1359673346 2973 dbSNP
rs1001301905 2979 dbSNP
rs981447556 2981 dbSNP
rs1365756890 2985 dbSNP
rs1032783172 2986 dbSNP
rs1412342815 2989 dbSNP
rs1421541552 2989 dbSNP
rs577378905 2994 dbSNP
rs1479052734 2995 dbSNP
rs1478399030 2996 dbSNP
rs747109956 3002 dbSNP
rs991379701 3003 dbSNP
rs909028005 3005 dbSNP
rs377114964 3006 dbSNP
rs771938770 3011 dbSNP
rs941862865 3011 dbSNP
rs1319984302 3015 dbSNP
rs1416713853 3015 dbSNP
rs1036080809 3022 dbSNP
rs1339710261 3023 dbSNP
rs3733126 3029 dbSNP
rs147010817 3030 dbSNP
rs879350599 3030 dbSNP
rs1365884188 3031 dbSNP
rs3733127 3032 dbSNP
rs888795568 3033 dbSNP
rs1432642496 3034 dbSNP
rs1170490715 3035 dbSNP
rs1311973118 3035 dbSNP
rs985494470 3042 dbSNP
rs9990236 3046 dbSNP
rs1192006317 3050 dbSNP
rs1268386757 3050 dbSNP
rs59211117 3050 dbSNP
rs796227729 3050 dbSNP
rs1432749159 3051 dbSNP
rs1039980799 3053 dbSNP
rs1487589632 3057 dbSNP
rs548589167 3063 dbSNP
rs1361323317 3066 dbSNP
rs1012191745 3069 dbSNP
rs879932380 3073 dbSNP
rs1220101871 3074 dbSNP
rs1020364756 3083 dbSNP
rs1037646905 3084 dbSNP
rs1256076657 3086 dbSNP
rs1225178915 3091 dbSNP
rs1331486430 3092 dbSNP
rs189032643 3094 dbSNP
rs879238486 3095 dbSNP
rs1300255566 3103 dbSNP
rs1384753183 3105 dbSNP
rs1345927505 3106 dbSNP
rs1331501178 3108 dbSNP
rs1445367258 3115 dbSNP
rs897369081 3116 dbSNP
rs1169144915 3120 dbSNP
rs527544578 3126 dbSNP
rs950291394 3130 dbSNP
rs1210626832 3135 dbSNP
rs145568367 3137 dbSNP
rs1431682555 3144 dbSNP
rs1002816274 3146 dbSNP
rs1449258532 3153 dbSNP
rs1236372506 3159 dbSNP
rs556466506 3159 dbSNP
rs1035626678 3188 dbSNP
rs1345581165 3191 dbSNP
rs570692986 3195 dbSNP
rs1032753464 3196 dbSNP
rs1230769878 3201 dbSNP
rs1318399557 3204 dbSNP
rs574788994 3220 dbSNP
rs892915605 3232 dbSNP
rs1452138618 3235 dbSNP
rs377628055 3236 dbSNP
rs148863609 3237 dbSNP
rs1403471858 3242 dbSNP
rs1302682235 3248 dbSNP
rs115703220 3249 dbSNP
rs963236942 3260 dbSNP
rs975990287 3261 dbSNP
rs1344746187 3264 dbSNP
rs1437300780 3272 dbSNP
rs1442988365 3273 dbSNP
rs1198588385 3277 dbSNP
rs746816860 3280 dbSNP
rs1327933832 3286 dbSNP
rs551747355 3292 dbSNP
rs1233786276 3302 dbSNP
rs918998112 3303 dbSNP
rs1286388333 3311 dbSNP
rs933033917 3312 dbSNP
rs1353277695 3319 dbSNP
rs1316563854 3320 dbSNP
rs954036118 3337 dbSNP
rs1341631714 3338 dbSNP
rs985461992 3339 dbSNP
rs909967489 3340 dbSNP
rs567799065 3343 dbSNP
rs910179182 3347 dbSNP
rs943023411 3349 dbSNP
rs950218647 3365 dbSNP
rs535191285 3375 dbSNP
rs927564832 3376 dbSNP
rs936988591 3377 dbSNP
rs1054531088 3379 dbSNP
rs1192583781 3383 dbSNP
rs879897270 3386 dbSNP
rs1487131899 3392 dbSNP
rs776055529 3394 dbSNP
rs1010416002 3395 dbSNP
rs1355056562 3401 dbSNP
rs1471032882 3402 dbSNP
rs1263098235 3403 dbSNP
rs1042308233 3405 dbSNP
rs560747364 3407 dbSNP
rs565903225 3410 dbSNP
rs1405843593 3411 dbSNP
rs1866300 3411 dbSNP
rs1002891241 3420 dbSNP
rs1392352879 3441 dbSNP
rs1390110881 3446 dbSNP
rs553325427 3448 dbSNP
rs1035740788 3458 dbSNP
rs1332276516 3461 dbSNP
rs866263959 3463 dbSNP
rs1467137920 3471 dbSNP
rs143627115 3476 dbSNP
rs1440470989 3477 dbSNP
rs1192720085 3478 dbSNP
rs748943934 3489 dbSNP
rs1028861620 3491 dbSNP
rs1248152168 3492 dbSNP
rs1199137893 3503 dbSNP
rs1012906909 3506 dbSNP
rs1287159778 3510 dbSNP
rs953336290 3510 dbSNP
rs1320675145 3511 dbSNP
rs1259267016 3515 dbSNP
rs1006809071 3518 dbSNP
rs1274558245 3520 dbSNP
rs17069638 3527 dbSNP
rs962801961 3530 dbSNP
rs1330689080 3541 dbSNP
rs963651641 3550 dbSNP
rs972017189 3564 dbSNP
rs1026542026 3565 dbSNP
rs1401024073 3574 dbSNP
rs918706124 3588 dbSNP
rs1463939850 3589 dbSNP
rs954528668 3591 dbSNP
rs981646213 3592 dbSNP
rs138196842 3594 dbSNP
rs1244595359 3598 dbSNP
rs1180047896 3605 dbSNP
rs910336401 3610 dbSNP
rs143867995 3613 dbSNP
rs781705444 3616 dbSNP
rs1236976135 3618 dbSNP
rs1198572442 3628 dbSNP
rs1456792352 3641 dbSNP
rs1281192217 3642 dbSNP
rs972110545 3648 dbSNP
rs1344629068 3658 dbSNP
rs1189945493 3663 dbSNP
rs937584210 3667 dbSNP
rs1242474962 3678 dbSNP
rs181472839 3680 dbSNP
rs563111354 3685 dbSNP
rs1360804734 3693 dbSNP
rs1444505148 3693 dbSNP
rs947598882 3694 dbSNP
rs1041846382 3698 dbSNP
rs1041991753 3700 dbSNP
rs186110216 3703 dbSNP
rs1328652959 3706 dbSNP
rs1176178797 3709 dbSNP
rs901637278 3710 dbSNP
rs1211346933 3713 dbSNP
rs542344244 3718 dbSNP
rs560989955 3721 dbSNP
rs1278558830 3726 dbSNP
rs1219112511 3733 dbSNP
rs1291973970 3736 dbSNP
rs1057137962 3737 dbSNP
rs1238016915 3737 dbSNP
rs1284699333 3738 dbSNP
rs1381337184 3738 dbSNP
rs1435447943 3738 dbSNP
rs1182962647 3739 dbSNP
rs1191512502 3739 dbSNP
rs1196273574 3739 dbSNP
rs1213809150 3739 dbSNP
rs1227706480 3739 dbSNP
rs1255877536 3739 dbSNP
rs1285575672 3739 dbSNP
rs1290603345 3739 dbSNP
rs1323599750 3739 dbSNP
rs1362824233 3739 dbSNP
rs1416659881 3739 dbSNP
rs1447128990 3739 dbSNP
rs1472718109 3739 dbSNP
rs754267860 3739 dbSNP
rs889000361 3739 dbSNP
rs1232163144 3740 dbSNP
rs894605126 3752 dbSNP
rs1295948154 3763 dbSNP
rs1339512328 3763 dbSNP
rs1434067390 3763 dbSNP
rs869110728 3763 dbSNP
rs1423023721 3764 dbSNP
rs1478263223 3765 dbSNP
rs1193682773 3766 dbSNP
rs1272080332 3769 dbSNP
rs745475866 3770 dbSNP
rs1362856611 3771 dbSNP
rs1189725397 3774 dbSNP
rs1163405157 3778 dbSNP
rs769361262 3783 dbSNP
rs1255340102 3784 dbSNP
rs1196380324 3786 dbSNP
rs560479630 3787 dbSNP
rs775149765 3789 dbSNP
rs1016647641 3790 dbSNP
rs899180906 3794 dbSNP
rs993780961 3800 dbSNP
rs527673842 3801 dbSNP
rs1247385529 3806 dbSNP
rs1220897254 3816 dbSNP
rs1026237513 3823 dbSNP
rs552334923 3828 dbSNP
rs1259906440 3829 dbSNP
rs1374835073 3829 dbSNP
rs1474578180 3830 dbSNP
rs954518935 3835 dbSNP
rs1317080676 3840 dbSNP
rs987340909 3849 dbSNP
rs1167542818 3854 dbSNP
rs1017347675 3856 dbSNP
rs190922611 3858 dbSNP
rs1367841619 3864 dbSNP
rs964490767 3866 dbSNP
rs74434492 3878 dbSNP
rs1436974387 3882 dbSNP
rs1392991354 3883 dbSNP
rs549530215 3887 dbSNP
rs1375394849 3896 dbSNP
rs773887576 3897 dbSNP
rs1401098601 3899 dbSNP
rs1466541296 3901 dbSNP
rs1423399937 3906 dbSNP
rs1295719282 3922 dbSNP
rs1168721333 3924 dbSNP
rs567937462 3933 dbSNP
rs945079311 3937 dbSNP
rs1322878872 3938 dbSNP
rs1190749510 3939 dbSNP
rs963018272 3942 dbSNP
rs1240040683 3967 dbSNP
rs1199197236 3969 dbSNP
rs1457232974 3974 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000295900.6 | 3UTR | UCAAGAUUUCCAAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.782 7.9e-4 0.687 4.7e-3 13 Click to see details
GSE14794 Lymphoblastoid cells 0.189 3.7e-2 0.179 4.6e-2 90 Click to see details
GSE17306 Multiple myeloma 0.246 4.4e-2 0.523 5.8e-5 49 Click to see details
GSE19350 CNS germ cell tumors -0.381 1.1e-1 0.196 2.7e-1 12 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.229 1.4e-1 0.218 1.5e-1 25 Click to see details
GSE32688 Pancreatic cancer -0.195 1.4e-1 -0.198 1.4e-1 32 Click to see details
GSE17498 Multiple myeloma 0.165 1.5e-1 0.216 9.0e-2 40 Click to see details
GSE38226 Liver fibrosis -0.209 1.8e-1 -0.249 1.4e-1 21 Click to see details
GSE21687 Ependynoma primary tumors 0.072 2.9e-1 0.063 3.1e-1 64 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.099 3.4e-1 0.284 1.1e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells 0.087 3.4e-1 0.262 1.1e-1 24 Click to see details
GSE28544 Breast cancer -0.081 3.5e-1 -0.089 3.4e-1 24 Click to see details
GSE21849 B cell lymphoma 0.066 3.7e-1 0.161 2.0e-1 29 Click to see details
GSE27834 Pluripotent stem cells 0.015 4.8e-1 0.056 4.2e-1 16 Click to see details
GSE27834 Pluripotent stem cells 0.015 4.8e-1 0.056 4.2e-1 16 Click to see details
GSE27834 Pluripotent stem cells 0.015 4.8e-1 0.056 4.2e-1 16 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KICH 0.38 0.03 0.391 0.03 24 Click to see details
LIHC -0.25 0.04 -0.226 0.06 49 Click to see details
CESC -0.98 0.06 -1.000 0.5 3 Click to see details
LUSC -0.194 0.12 -0.255 0.06 38 Click to see details
BLCA 0.264 0.15 0.404 0.05 17 Click to see details
KIRC -0.123 0.16 -0.063 0.31 65 Click to see details
LUAD -0.32 0.17 -0.400 0.11 11 Click to see details
PRAD 0.123 0.2 0.092 0.27 48 Click to see details
KIRP -0.155 0.2 -0.128 0.25 31 Click to see details
CHOL 0.24 0.27 0.317 0.2 9 Click to see details
PAAD 0.464 0.27 0.400 0.3 4 Click to see details
ESCA -0.232 0.27 -0.267 0.24 9 Click to see details
HNSC -0.094 0.28 -0.084 0.3 42 Click to see details
UCEC -0.123 0.31 -0.200 0.21 19 Click to see details
THCA 0.051 0.35 0.007 0.48 59 Click to see details
STAD -0.06 0.38 -0.202 0.15 29 Click to see details
BRCA -0.031 0.39 -0.083 0.23 79 Click to see details
BRCA -0.031 0.39 -0.083 0.23 79 Click to see details
BRCA -0.031 0.39 -0.083 0.23 79 Click to see details
BRCA -0.031 0.39 -0.083 0.23 79 Click to see details
87 hsa-miR-452-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT150000 MIDN midnolin 2 10
MIRT330600 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT358701 SUB1 SUB1 homolog, transcriptional regulator 2 4
MIRT362854 EIF4H eukaryotic translation initiation factor 4H 2 2
MIRT447215 ATXN7 ataxin 7 2 2
MIRT466655 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 6
MIRT483979 PANK1 pantothenate kinase 1 2 8
MIRT485118 SF3B3 splicing factor 3b subunit 3 2 2
MIRT488864 AUTS8 Autism, susceptibility to, 8 2 2
MIRT492293 SH2B3 SH2B adaptor protein 3 2 2
MIRT492976 NCK2 NCK adaptor protein 2 2 2
MIRT497410 LRRC40 leucine rich repeat containing 40 2 2
MIRT511143 MRPL17 mitochondrial ribosomal protein L17 2 6
MIRT512650 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT513017 NSFL1C NSFL1 cofactor 2 6
MIRT520445 TSPAN2 tetraspanin 2 2 6
MIRT527995 NDNF neuron derived neurotrophic factor 2 2
MIRT528667 PDE4DIP phosphodiesterase 4D interacting protein 2 2
MIRT533512 TRIM71 tripartite motif containing 71 2 2
MIRT537404 FBXO47 F-box protein 47 2 2
MIRT538161 DCP2 decapping mRNA 2 2 2
MIRT539124 ARHGEF17 Rho guanine nucleotide exchange factor 17 2 2
MIRT540666 MIS18A MIS18 kinetochore protein A 2 4
MIRT542948 GDF11 growth differentiation factor 11 2 2
MIRT547534 MAML3 mastermind like transcriptional coactivator 3 2 2
MIRT559033 C20orf24 chromosome 20 open reading frame 24 2 4
MIRT559554 ARF6 ADP ribosylation factor 6 2 2
MIRT570177 RCBTB1 RCC1 and BTB domain containing protein 1 2 2
MIRT573149 ITGA9 integrin subunit alpha 9 2 2
MIRT575849 Rab1 RAB1A, member RAS oncogene family 1 1
MIRT611034 RRP1B ribosomal RNA processing 1B 2 2
MIRT616281 HMGB1 high mobility group box 1 2 2
MIRT618372 PRKG2 protein kinase, cGMP-dependent, type II 2 2
MIRT619540 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT622303 SGIP1 SH3 domain GRB2 like endophilin interacting protein 1 2 2
MIRT622590 PRRG4 proline rich and Gla domain 4 2 2
MIRT624441 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT637089 KLRD1 killer cell lectin like receptor D1 2 2
MIRT639084 ADCYAP1 adenylate cyclase activating polypeptide 1 2 2
MIRT639334 NINJ1 ninjurin 1 2 2
MIRT639798 EIF3E eukaryotic translation initiation factor 3 subunit E 2 2
MIRT640851 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT641628 KIAA1244 ARFGEF family member 3 1 1
MIRT642634 EPPIN epididymal peptidase inhibitor 2 2
MIRT643053 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT643416 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT645586 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT647393 FAM181B family with sequence similarity 181 member B 2 2
MIRT649411 CDC14B cell division cycle 14B 2 2
MIRT649477 CLDN16 claudin 16 2 2
MIRT651307 ZDHHC20 zinc finger DHHC-type containing 20 2 2
MIRT651387 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT653411 SLC7A2 solute carrier family 7 member 2 2 2
MIRT654084 RSPH4A radial spoke head 4 homolog A 2 2
MIRT654613 PTPRM protein tyrosine phosphatase, receptor type M 2 2
MIRT655338 PCP4L1 Purkinje cell protein 4 like 1 2 2
MIRT656173 MRPL44 mitochondrial ribosomal protein L44 2 2
MIRT657272 HS3ST3B1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 2 2
MIRT657881 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 2
MIRT659875 CAPRIN1 cell cycle associated protein 1 2 2
MIRT662381 ICA1L islet cell autoantigen 1 like 2 4
MIRT666308 SLC22A3 solute carrier family 22 member 3 2 2
MIRT667274 NAV1 neuron navigator 1 2 2
MIRT667614 LIMCH1 LIM and calponin homology domains 1 2 2
MIRT674242 NUP62 nucleoporin 62 2 4
MIRT690386 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT693402 NUDT16 nudix hydrolase 16 2 2
MIRT702503 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT708632 STMN4 stathmin 4 2 2
MIRT708839 SCAND3 zinc finger BED-type containing 9 1 1
MIRT709016 HSBP1 heat shock factor binding protein 1 2 2
MIRT709235 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT710885 PARL presenilin associated rhomboid like 2 2
MIRT712262 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT712573 ATP2B4 ATPase plasma membrane Ca2+ transporting 4 2 2
MIRT715046 PRPF38A pre-mRNA processing factor 38A 2 2
MIRT718905 GALR1 galanin receptor 1 2 2
MIRT719368 FEM1A fem-1 homolog A 2 2
MIRT719495 SEC24B SEC24 homolog B, COPII coat complex component 2 2
MIRT719601 PRKX protein kinase, X-linked 2 2
MIRT719891 RRP36 ribosomal RNA processing 36 2 2
MIRT720063 ZNF449 zinc finger protein 449 2 2
MIRT721679 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT721724 VTI1A vesicle transport through interaction with t-SNAREs 1A 2 2
MIRT723370 ZNF470 zinc finger protein 470 2 2
MIRT724941 TXNL1 thioredoxin like 1 2 2
MIRT725302 NLRC5 NLR family CARD domain containing 5 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-452 Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-452 Phenethyl isothiocyanate(PEITC) NULL 16741 Microarray neonatal mice liver 20145010 2010 up-regulated
miR-452 Tert-butyl hydroperoxide (t-BHP) NULL 6410 Microarray mouse auditory cells 20510889 2010 down-regulated
miR-452 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (BGC823)
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-mir-452 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant cell line (BGC-823)
hsa-miR-452-3p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-452-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-452-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-452-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (HCT8)
hsa-miR-452-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-452-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-452-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-452-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-452-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-452-3p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)

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