miRTarBase - #MIRT447283


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pre-miRNA Information
pre-miRNA hsa-mir-4656   
Genomic Coordinates chr7: 4788565 - 4788639
Description Homo sapiens miR-4656 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4656
Sequence 10| UGGGCUGAGGGCAGGAGGCCUGU |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1257485407 2 dbSNP
rs71535143 5 dbSNP
rs933178228 7 dbSNP
rs895666746 9 dbSNP
rs1053330554 11 dbSNP
rs1327822621 13 dbSNP
rs934599733 16 dbSNP
rs1260841927 19 dbSNP
rs1371177672 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LAPTM5   
Synonyms CLAST6
Description lysosomal protein transmembrane 5
Transcript NM_006762   
Expression
Putative miRNA Targets on LAPTM5
3'UTR of LAPTM5
(miRNA target sites are highlighted)		 
>LAPTM5|NM_006762|3'UTR
   1 CCCTCGCCAGGCCCCAGCCCCAGTGCTGGGAGGGGTGGAGCTGCCTCATAATCTGCTTTTTTGCTTTGGTGGCCCCTGTG
  81 GCCTGGGTGGGCCCTCCCGCCCCTCCCTGGCAGGACAATCTGCTTGTGTCTCCCTCGCTGGCCTGCTCCTCCTGCAGGGC
 161 CTGTGAGCTGCTCACAACTGGGTCAACGCTTTAGGCTGAGTCACTCCTCGGGTCTCTCCATAATTCAGCCCAACAATGCT
 241 TGGTTTATTTCAATCAGCTCTGACACTTGTTTAGACGATTGGCCATTCTAAAGTTGGTGAGTTTGTCAAGCAACTATCGA
 321 CTTGATCAGTTCAGCCAAGCAACTGACAAATCAAAAACCCACTTGTCAGTTCAGTAAAATAATTTGGTCAAACAACAGTC
 401 TATTGCATTGATTTATAAATAGTTGTCAGTTCACATAGCAATTTAATCAAGTAATCATTAATTAGTTACCCCCTATATAT
 481 AAATATATGTAATCAATTTCTTCAAATAGCTTGCTTACATGATAATCAATTAGCCAACCATGAGTCATTTAGAATAGTGA
 561 TAAATAGAATACACAGAATAGTGATGAAATTCAATTTAAAAAATCACGTTAGCCTCCAAACCATTTAATTCAAATGAACC
 641 CATCAACTGGATGCCAACTCTGGCGAATGTAGGACCTCTGAGTGGCTGTATAATTGTTAATTCAAATGAAATTCATTTAA
 721 ACAGTTGACAAACTGTCATTCAACAATTAGCTCCAGGAAATAACAGTTATTTCATCATAAAACAGTCCCTTCAAACACAC
 801 AATTGTTCTGCTGAAGAGTTGTCATCAACAATCCAATGCTCACCTATTCAGTTGCTCTGTGGTCAGTGTGGCTGCATAAC
 881 AGTGGATTCCATGAAAGGAGTCATTTTAGTGATGAGCTGCCAGTCCATTCCCAGGCCAGGCTGTCGCTGGCCATCCATTC
 961 AGTCGATTCAGTCATAGGCGAATCTGTTCTGCCCGAGGCTTGTGGTCAAGCAAAAATTCAGCCCTGAAATCAGGCACATC
1041 TGTTCGTTGGACTAAACCCACAGGTTAGTTCAGTCAAAGCAGGCAACCCCCTTGTGGGCACTGACCCTGCCACTGGGGTC
1121 ATGGCGGTTGTGGCAGCTGGGGAGGTTTGGCCCCAACAGCCCTCCTGTGCCTGCTTCCCTGTGTGTCGGGGTCCTCCAGG
1201 GAGCTGACCCAGAGGTGGAGGCCACGGAGGCAGGGTCTCTGGGGACTGTCGGGGGGTACAGAGGGAGAAGGCTCTGCAAG
1281 AGCTCCCTGGCAATACCCCCTTGTGTAATTGCTTTGTGTGCGACAGGGAGGAAGTTTCAATAAAGCAGCAACAAGCTTCT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugUCCGGAGGACGG----GAGUCGGGu 5'
            :||:|||:  ||    :||||||| 
Target 5' tcGGGTCTCT--CCATAATTCAGCCCa 3'
 208 - 232 155.00 -28.20
2 
miRNA  3' ugUCCGGAGGACGG---------GAGUCGGGu 5'
            ||||:| : |:|         :||||||| 
Target 5' cgAGGCTTGTGGTCAAGCAAAAATTCAGCCCt 3'
 994 - 1025 149.00 -22.70
3 
miRNA  3' uguCCGGAGGACGGGAGUCGGGu 5'
             ||::| :| |  |||||:| 
Target 5' cttGGTTTATTTCAATCAGCTCt 3'
 239 - 261 140.00 -14.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30179951 1 COSMIC
COSN30707987 1 COSMIC
COSN18725328 38 COSMIC
COSN31578172 51 COSMIC
COSN26639487 92 COSMIC
COSN30626378 98 COSMIC
COSN30083313 99 COSMIC
COSN8638154 102 COSMIC
COSN26727154 318 COSMIC
COSN20058794 319 COSMIC
COSN7470173 563 COSMIC
COSN14438329 779 COSMIC
COSN24471340 879 COSMIC
COSN16350263 1091 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs751735631 4 dbSNP
rs766623674 5 dbSNP
rs1409746650 6 dbSNP
rs368151353 6 dbSNP
rs1047534674 7 dbSNP
rs773601185 8 dbSNP
rs367914977 9 dbSNP
rs1416995462 10 dbSNP
rs777279768 13 dbSNP
rs1486235288 18 dbSNP
rs768222910 21 dbSNP
rs942836563 22 dbSNP
rs989400713 23 dbSNP
rs1489224104 24 dbSNP
rs746538562 28 dbSNP
rs1484053101 32 dbSNP
rs779751267 34 dbSNP
rs762572720 36 dbSNP
rs746538740 37 dbSNP
rs3795438 38 dbSNP
rs1305515021 40 dbSNP
rs1234845792 41 dbSNP
rs370870412 45 dbSNP
rs778766278 46 dbSNP
rs1312159906 47 dbSNP
rs1228988707 62 dbSNP
rs1366030940 66 dbSNP
rs1302692785 70 dbSNP
rs1399951670 85 dbSNP
rs1002418709 88 dbSNP
rs1294309132 89 dbSNP
rs1312221952 89 dbSNP
rs1369048264 96 dbSNP
rs757918780 98 dbSNP
rs757009420 99 dbSNP
rs1393969166 104 dbSNP
rs1398613196 104 dbSNP
rs750114612 106 dbSNP
rs1461101343 107 dbSNP
rs749943141 108 dbSNP
rs1431910532 109 dbSNP
rs1482776100 111 dbSNP
rs1166660131 116 dbSNP
rs1434391393 118 dbSNP
rs1475700740 121 dbSNP
rs536309221 123 dbSNP
rs977469019 124 dbSNP
rs1177688263 125 dbSNP
rs777713534 129 dbSNP
rs755015211 133 dbSNP
rs967084529 134 dbSNP
rs778491128 136 dbSNP
rs756505338 137 dbSNP
rs1214590320 138 dbSNP
rs1335185338 139 dbSNP
rs1278099469 142 dbSNP
rs958524538 144 dbSNP
rs1292429535 146 dbSNP
rs1447099461 151 dbSNP
rs763221228 151 dbSNP
rs1314003545 154 dbSNP
rs1231274519 157 dbSNP
rs567418398 159 dbSNP
rs1307683137 160 dbSNP
rs750675040 166 dbSNP
rs113052491 173 dbSNP
rs1349021204 174 dbSNP
rs1037465876 178 dbSNP
rs1260535963 181 dbSNP
rs1410813557 184 dbSNP
rs1375440238 185 dbSNP
rs1301568631 186 dbSNP
rs145547723 187 dbSNP
rs1461658199 188 dbSNP
rs1377646145 198 dbSNP
rs1393338010 201 dbSNP
rs762280276 209 dbSNP
rs530563188 210 dbSNP
rs769318025 211 dbSNP
rs761313568 212 dbSNP
rs775127366 213 dbSNP
rs1254990751 215 dbSNP
rs1194404199 217 dbSNP
rs1263510345 231 dbSNP
rs764833877 232 dbSNP
rs1271575385 234 dbSNP
rs1025576550 235 dbSNP
rs994544213 238 dbSNP
rs545825544 242 dbSNP
rs1261167554 245 dbSNP
rs1202062592 253 dbSNP
rs745856514 254 dbSNP
rs888672180 257 dbSNP
rs1238279829 264 dbSNP
rs752997168 265 dbSNP
rs376947062 276 dbSNP
rs1304963287 279 dbSNP
rs1229439576 287 dbSNP
rs1038860097 290 dbSNP
rs942823690 293 dbSNP
rs571174890 296 dbSNP
rs1398261742 298 dbSNP
rs139954312 299 dbSNP
rs368580907 299 dbSNP
rs767047113 299 dbSNP
rs201454088 300 dbSNP
rs1323496464 303 dbSNP
rs1051230974 305 dbSNP
rs934179052 306 dbSNP
rs1390439166 313 dbSNP
rs1386173654 316 dbSNP
rs1159423094 317 dbSNP
rs79297199 318 dbSNP
rs1452237517 319 dbSNP
rs1397477856 324 dbSNP
rs1174339463 329 dbSNP
rs922768324 332 dbSNP
rs1251305774 333 dbSNP
rs1320062038 338 dbSNP
rs1040809558 344 dbSNP
rs768030377 347 dbSNP
rs913550688 352 dbSNP
rs989528522 368 dbSNP
rs760019670 379 dbSNP
rs1356128386 398 dbSNP
rs1282715875 404 dbSNP
rs1247428649 407 dbSNP
rs1305612120 422 dbSNP
rs1341662962 422 dbSNP
rs1408915900 423 dbSNP
rs945664630 427 dbSNP
rs1320848904 434 dbSNP
rs1396714144 435 dbSNP
rs1388327641 438 dbSNP
rs1164839902 445 dbSNP
rs1458215605 447 dbSNP
rs914282147 448 dbSNP
rs1314226940 453 dbSNP
rs990296785 455 dbSNP
rs1249930522 465 dbSNP
rs752103634 470 dbSNP
rs1189457409 471 dbSNP
rs28362505 474 dbSNP
rs539596515 475 dbSNP
rs1212051283 480 dbSNP
rs1189166737 486 dbSNP
rs980660598 505 dbSNP
rs141538379 506 dbSNP
rs970534336 515 dbSNP
rs1304958853 519 dbSNP
rs1226787047 521 dbSNP
rs370229354 529 dbSNP
rs1343688612 533 dbSNP
rs6684975 538 dbSNP
rs1024796152 539 dbSNP
rs1297623754 542 dbSNP
rs1439501342 552 dbSNP
rs1476471768 558 dbSNP
rs981246327 566 dbSNP
rs1250294677 569 dbSNP
rs1325078126 576 dbSNP
rs971230628 579 dbSNP
rs1395438571 593 dbSNP
rs1166671093 594 dbSNP
rs1181522152 596 dbSNP
rs1169382981 599 dbSNP
rs1477723938 605 dbSNP
rs1245254474 606 dbSNP
rs992857792 607 dbSNP
rs1452580685 608 dbSNP
rs548812716 608 dbSNP
rs994099278 610 dbSNP
rs11541205 613 dbSNP
rs144695098 614 dbSNP
rs763068236 616 dbSNP
rs888461983 622 dbSNP
rs1218170768 638 dbSNP
rs543389078 640 dbSNP
rs577942657 650 dbSNP
rs997140346 657 dbSNP
rs901328570 661 dbSNP
rs1336830411 663 dbSNP
rs1051139284 664 dbSNP
rs998275693 665 dbSNP
rs1440787874 669 dbSNP
rs1041258433 670 dbSNP
rs777684392 687 dbSNP
rs201964781 689 dbSNP
rs541670654 691 dbSNP
rs1174541477 693 dbSNP
rs902684191 706 dbSNP
rs1411494706 716 dbSNP
rs1043031694 729 dbSNP
rs1484222928 736 dbSNP
rs1804623 757 dbSNP
rs1253229841 764 dbSNP
rs1330406917 764 dbSNP
rs947022413 767 dbSNP
rs113531450 769 dbSNP
rs1393363097 771 dbSNP
rs892182702 774 dbSNP
rs1328120117 784 dbSNP
rs199814092 793 dbSNP
rs572653556 800 dbSNP
rs937008566 802 dbSNP
rs1230059846 814 dbSNP
rs1350833750 817 dbSNP
rs1053549331 824 dbSNP
rs936297223 836 dbSNP
rs926350384 843 dbSNP
rs1336310719 857 dbSNP
rs1470513233 862 dbSNP
rs1388229566 863 dbSNP
rs1157187052 864 dbSNP
rs1473788880 876 dbSNP
rs1234683618 878 dbSNP
rs8048 879 dbSNP
rs8056 886 dbSNP
rs1239707856 891 dbSNP
rs1210289393 897 dbSNP
rs1464034339 900 dbSNP
rs973049403 912 dbSNP
rs1253924643 914 dbSNP
rs1214041483 919 dbSNP
rs1288810035 927 dbSNP
rs1226387256 938 dbSNP
rs1381334125 941 dbSNP
rs962682509 942 dbSNP
rs1017282984 952 dbSNP
rs1318820819 958 dbSNP
rs1006819174 959 dbSNP
rs1164582785 960 dbSNP
rs1403948408 964 dbSNP
rs573767490 965 dbSNP
rs1029665576 971 dbSNP
rs140866709 975 dbSNP
rs1190131676 979 dbSNP
rs3795439 985 dbSNP
rs1016059610 989 dbSNP
rs143367007 994 dbSNP
rs1042588725 995 dbSNP
rs191218545 997 dbSNP
rs1290531939 1000 dbSNP
rs1312039928 1003 dbSNP
rs1280783636 1023 dbSNP
rs552861844 1031 dbSNP
rs1341546126 1036 dbSNP
rs115524147 1045 dbSNP
rs1437349075 1046 dbSNP
rs1369757605 1047 dbSNP
rs1055396927 1048 dbSNP
rs1443514158 1051 dbSNP
rs1293126271 1057 dbSNP
rs997083264 1058 dbSNP
rs936956080 1062 dbSNP
rs901402215 1064 dbSNP
rs565678419 1074 dbSNP
rs1019892896 1080 dbSNP
rs1318175681 1095 dbSNP
rs1388846153 1100 dbSNP
rs926948071 1106 dbSNP
rs117174760 1113 dbSNP
rs949860003 1125 dbSNP
rs1189047867 1126 dbSNP
rs377478565 1128 dbSNP
rs918398770 1128 dbSNP
rs149189353 1140 dbSNP
rs1020114903 1143 dbSNP
rs750987530 1145 dbSNP
rs1010019341 1146 dbSNP
rs1053945960 1147 dbSNP
rs936469941 1158 dbSNP
rs1276683080 1160 dbSNP
rs972569354 1164 dbSNP
rs1308105337 1179 dbSNP
rs904842024 1184 dbSNP
rs185507927 1188 dbSNP
rs949072369 1194 dbSNP
rs909771526 1206 dbSNP
rs985348797 1210 dbSNP
rs1050731 1212 dbSNP
rs1409599726 1218 dbSNP
rs1050732 1224 dbSNP
rs1469602839 1225 dbSNP
rs1240130592 1228 dbSNP
rs1310368694 1229 dbSNP
rs917803229 1231 dbSNP
rs761704013 1235 dbSNP
rs1050733 1239 dbSNP
rs1029654181 1245 dbSNP
rs1434478361 1249 dbSNP
rs976791237 1250 dbSNP
rs966841309 1251 dbSNP
rs940479823 1253 dbSNP
rs1481003902 1254 dbSNP
rs909084951 1255 dbSNP
rs984604503 1256 dbSNP
rs1011044202 1257 dbSNP
rs1228220421 1257 dbSNP
rs1284131628 1257 dbSNP
rs893974504 1257 dbSNP
rs1033891206 1260 dbSNP
rs1050739 1261 dbSNP
rs550215498 1263 dbSNP
rs539745250 1264 dbSNP
rs1050746 1267 dbSNP
rs952850342 1269 dbSNP
rs1400884847 1273 dbSNP
rs1050748 1274 dbSNP
rs1269971747 1279 dbSNP
rs9146 1280 dbSNP
rs1347416394 1287 dbSNP
rs949772149 1291 dbSNP
rs896874676 1292 dbSNP
rs1467249200 1293 dbSNP
rs1050752 1294 dbSNP
rs975383916 1296 dbSNP
rs965380632 1299 dbSNP
rs1182457165 1302 dbSNP
rs1037198795 1305 dbSNP
rs941166616 1306 dbSNP
rs768481058 1309 dbSNP
rs1462696127 1320 dbSNP
rs1264016081 1321 dbSNP
rs1019840390 1322 dbSNP
rs1009863118 1325 dbSNP
rs1327531247 1334 dbSNP
rs985337567 1348 dbSNP
rs1240188316 1352 dbSNP
rs1376161437 1355 dbSNP
rs564458693 1359 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uguccggaggacggGAGUCgggu 5'
                        :||||    
Target 5' ---ucaagcaaaaaUUCAG---- 3'
 		1 - 16
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000294507.3 | 3UTR | UCAAGCAAAAAUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000294507.3 | 3UTR | UCAAGCAAAAAUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
48 hsa-miR-4656 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT135536 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT168127 SOX4 SRY-box 4 2 2
MIRT301229 SH3BP4 SH3 domain binding protein 4 2 2
MIRT444362 TIMM8B translocase of inner mitochondrial membrane 8 homolog B 2 2
MIRT445909 SLC10A3 solute carrier family 10 member 3 2 2
MIRT447283 LAPTM5 lysosomal protein transmembrane 5 2 2
MIRT453797 KBTBD12 kelch repeat and BTB domain containing 12 2 2
MIRT456777 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT459647 PCSK9 proprotein convertase subtilisin/kexin type 9 2 2
MIRT462333 BCL7B BCL tumor suppressor 7B 2 2
MIRT463535 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT465799 TMEM91 transmembrane protein 91 2 2
MIRT470647 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT470837 PLXND1 plexin D1 2 2
MIRT471129 PHF19 PHD finger protein 19 2 2
MIRT483310 SLC35C2 solute carrier family 35 member C2 2 2
MIRT487264 CCNF cyclin F 2 2
MIRT491731 SEMA3F semaphorin 3F 2 2
MIRT497195 DRP2 dystrophin related protein 2 2 2
MIRT508384 SPTBN2 spectrin beta, non-erythrocytic 2 2 4
MIRT530496 FADS6 fatty acid desaturase 6 2 2
MIRT546995 PPP2CA protein phosphatase 2 catalytic subunit alpha 2 2
MIRT549790 KIAA0391 KIAA0391 2 2
MIRT560368 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT566000 RNF4 ring finger protein 4 2 2
MIRT574035 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT574231 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT576139 Hmox1 heme oxygenase 1 2 2
MIRT576640 Mill2 MHC I like leukocyte 2 1 1
MIRT609875 RAD54L2 RAD54 like 2 2 4
MIRT622651 POU2F3 POU class 2 homeobox 3 2 4
MIRT628848 FAM151B family with sequence similarity 151 member B 2 2
MIRT634252 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT634672 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT649087 FBXO25 F-box protein 25 2 2
MIRT665019 ELK1 ELK1, ETS transcription factor 2 2
MIRT666939 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT668960 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT675802 MED28 mediator complex subunit 28 2 2
MIRT684022 FOLR1 folate receptor 1 2 2
MIRT696480 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT705894 ADCY9 adenylate cyclase 9 2 2
MIRT709434 ZSCAN25 zinc finger and SCAN domain containing 25 2 2
MIRT713572 SLC2A8 solute carrier family 2 member 8 2 2
MIRT716697 HLA-B major histocompatibility complex, class I, B 2 2
MIRT719735 SLC39A11 solute carrier family 39 member 11 2 2
MIRT724907 DAO D-amino acid oxidase 2 2
MIRT725321 NFASC neurofascin 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4656 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4656 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4656 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4656 Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-4656 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-4656 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-4656 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4656 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4656 Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-4656 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)

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