miRTarBase - #MIRT447422


—
pre-miRNA Information
pre-miRNA hsa-mir-6833   
Genomic Coordinates chr6: 32179816 - 32179876
Description Homo sapiens miR-6833 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6833-5p
Sequence 6| GUGUGGAAGAUGGGAGGAGAAA |27
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs764873407 1 dbSNP
rs1232535042 3 dbSNP
rs574738502 14 dbSNP
Putative Targets

Gene Information
Gene Symbol MED21   
Synonyms SRB7, SURB7, hSrb7
Description mediator complex subunit 21
Transcript NM_004264   
Expression
Putative miRNA Targets on MED21
3'UTR of MED21
(miRNA target sites are highlighted)		 
>MED21|NM_004264|3'UTR
   1 CATCAGTGGATACCATGTGGCTGAGAAAAGAACTGTTTGAGTGCCATTAAGAATTCTGCATCAGACTTAGATACAAGCCT
  81 TACCAACAATTACAGAAACATTAAACACTATGACACATTACCTTTTTAGCTATTTTTAATAGTCTTCTATTTTCACTCTT
 161 GATAAGCTTATAAAATCATGATTGAATCAGCTTTAAAGCATCATACCATCATTTTTTAACTGAGTGAAATTATTAAGGCA
 241 TGTAATACATTAATGAACATAATATAAGGAAACATATGTAAAATTCTGTTATGACATAATTTATGTCTCCATTTTGTTGT
 321 ATTGGCCAGTACTTTTACAAATCAAAACATCTCTCAAGCCAAAGGAGAAGACAGTAAGAACAGACATAAGGGACATTTTA
 401 GTTTGGGCTAGTGTCCTGCCTCTTAGAGGTGGCATTGTGTAAATCTGAGCTTTGAGCAAGAAAGTTTTGGAAATTGTGTT
 481 GCTTTTAAGAAATAGAGTTAGTGTGGCTGGATAAGAAAGTCACATTTATGCAAATGTTTCTTCTGCTAGAACCTCATACC
 561 TGTTCTAGTTCATCTCCACGTTTATTTTACCAAGAGATCCTCTGTCAAGAGAATTTCCTGGCTGTTGTGAAAGAATTTTT
 641 CTACATCCTGAACTATTTTTCCTATTTCTTTTCACCTTGCTTTTTTTCATCCTTAATTTGCTTGTCATCACAATGAAGTA
 721 TGTTTTTTGAATCATCAATTCTTTCTCATTCTCCATTTATCTGAAGGTTCTTTTGCCCTTATTAACCTCTCAACTTTTAT
 801 TGCTGTATTCTAGTCAGACCAGAACATACTTCCACTACATCAGTTACTTGGCATCATTTCACCTCAGTTTATTATTGCCA
 881 AATAATAATTTGTGTCAGCATTTTCAACTATGGTTATTCATCCAACCCTTGGATCTCTTTGAGTCTACTGATAATCTCCA
 961 CTGGAAAGGTGGAATTGAAATGTGGTCCACATTTTAACTAGCTATTTCCTGGGGCTGTATTTTTCAGAATATGCTGAGCT
1041 ACATTTGCTGCAATCTGTTGCTATTCAGAGTTTAAGTTTCAGGAGAAAACAGGAACAATAGAACACTCTGCCTGTTATTT
1121 TTGTTGTAATCAAGCTTTTCCACAGTTCTTGAAAAGTACTATGTTTCAAATTTCAGGAACACCAGCGTTAGCTGTAAAAG
1201 TTGCAGCAATTTATTGGCTAGTCATAGAAAATTTTTGAACTTTTAACTGTATTTTAATTGATGTTTATTAAAAACACTTT
1281 GCTATCAGATATTTGGCATAAATCTGTACTCTTCATTATAGTTTTGGGGGGAGAGAAGATTCAGTCAGAAAACTTATTCA
1361 AAGTACCTAAGTATTATAAAGGAGTCAAAAAGGTACAAAGAGAAAAGGTCAAGACATTTTTCAAATGAGGGAAAACTAAC
1441 AGGATTTATCACTAGTAAACCTGCTCTAAAAGAATTCAAGGGAAGCTTTTTAAAAAGAAGGGAAGTTATAGCAGAAGGAA
1521 ACTTAGAATGGCAGGAATAAAGAAGGCATAATGTATAGGGTAAATATAATAGACTTCTCTTGAGGTTTTAAAAATTACAT
1601 TTGTTATTTGAAAGAAAAAAATTAACGTTGTTGTATGTGATTCTCTGTAGAGGATATACAGTTTTTTTTTGTTGTTCTTG
1681 TTTCTGTTTTTTTAAGGTGAAGTCTCTGTCACCCAAGCTGAAGTGCAGTTCTGTGATCATGGCTCACTGCAGCTTCACCC
1761 TGGGTTCAGGTGATCCTCCCACTTCAGCCTCTTCAGTAACTGGGACTACAGGCATGTACTACCACGTCCAGCTAATTTTT
1841 TTTTTCTTTTTTTTTTAGAGATGGGGTCTCACTCTGTTGCCCAGGCTAATGCCAAACTGCTAACCTCAAGATATTAATAC
1921 TATACAGTAGACTATAAGAAATTAAGTATTTGTATCATCCCTAGAGCGACACAGATTTTTCCCTAAAAAACTACAGATTA
2001 TTTTCAAAAGCATTAATAAATTAAGGTGGAATACTAAAAAAGATTCAGGTAACCCAGGAACGAGAAACAGAATAAAACAA
2081 TAGTAAACCTAAATTTTATTTTATTTCATTAATACAGCAATAATTAAATGTCAATGATCTAAGCTGATTTAAATCTAAAA
2161 ACTGGATAAGAAGCTGTGGCTTGTAATTAAAAATAGACCTTTATTCACTAGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aaagaggaggguAGAAGGUGUg 5'
                      |:||||||| 
Target 5' ttgtaatcaagcTTTTCCACAg 3'
 1124 - 1145 146.00 -10.00
2 
miRNA  3' aaagaggaggGUA-GAAGGUGug 5'
                    ||| |||||||  
Target 5' cagaccagaaCATACTTCCACta 3'
 815 - 837 132.00 -13.30
3 
miRNA  3' aaagaggaggguAGAAGGUGUg 5'
                      |:|||:||| 
Target 5' ttgtgaaagaatTTTTCTACAt 3'
 625 - 646 130.00 -7.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30159984 24 COSMIC
COSN30136749 31 COSMIC
COSN30684591 44 COSMIC
COSN30486269 51 COSMIC
COSN30145804 61 COSMIC
COSN31582936 127 COSMIC
COSN31517744 135 COSMIC
COSN31573196 176 COSMIC
COSN30167330 279 COSMIC
COSN15712818 354 COSMIC
COSN21305433 472 COSMIC
COSN22659158 986 COSMIC
COSN20041924 1671 COSMIC
COSN30706242 1671 COSMIC
COSN28569337 1722 COSMIC
COSN26857064 1729 COSMIC
COSN26860517 1733 COSMIC
COSN21726035 1846 COSMIC
COSN24736463 1847 COSMIC
COSN29562226 1857 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1435804333 1 dbSNP
rs1273220665 2 dbSNP
rs772187197 3 dbSNP
rs1242151706 4 dbSNP
rs1286695075 6 dbSNP
rs773409750 14 dbSNP
rs760868894 16 dbSNP
rs765012162 18 dbSNP
rs1021856185 21 dbSNP
rs1197537140 30 dbSNP
rs775159262 31 dbSNP
rs762896533 33 dbSNP
rs376889723 38 dbSNP
rs763909292 39 dbSNP
rs1356618165 44 dbSNP
rs374293876 47 dbSNP
rs756818432 50 dbSNP
rs567433509 59 dbSNP
rs775793333 65 dbSNP
rs1361885633 75 dbSNP
rs1158951717 78 dbSNP
rs996139413 86 dbSNP
rs1405586387 90 dbSNP
rs1028996583 91 dbSNP
rs1157105960 92 dbSNP
rs1256631205 104 dbSNP
rs1187322414 107 dbSNP
rs954994847 108 dbSNP
rs8628 120 dbSNP
rs1216820744 134 dbSNP
rs1316532712 141 dbSNP
rs1282637779 144 dbSNP
rs912408486 145 dbSNP
rs961215792 146 dbSNP
rs190228266 150 dbSNP
rs1293278449 152 dbSNP
rs375578150 156 dbSNP
rs192721277 157 dbSNP
rs547991731 165 dbSNP
rs1376958911 172 dbSNP
rs930984431 176 dbSNP
rs1307534741 179 dbSNP
rs1044072790 183 dbSNP
rs1343029044 185 dbSNP
rs117875155 186 dbSNP
rs1237626264 189 dbSNP
rs1416875601 193 dbSNP
rs149854106 199 dbSNP
rs774451631 203 dbSNP
rs1056857925 205 dbSNP
rs1265485415 207 dbSNP
rs1187133236 212 dbSNP
rs1485668684 218 dbSNP
rs1240518217 222 dbSNP
rs1224031774 223 dbSNP
rs1469243121 224 dbSNP
rs780675444 229 dbSNP
rs761855749 239 dbSNP
rs112758033 243 dbSNP
rs1295709327 246 dbSNP
rs554773558 249 dbSNP
rs1359440841 254 dbSNP
rs184200647 255 dbSNP
rs189910297 256 dbSNP
rs1441174449 259 dbSNP
rs1029028158 267 dbSNP
rs144364611 274 dbSNP
rs370174980 275 dbSNP
rs1467140554 280 dbSNP
rs1026297726 287 dbSNP
rs768030401 289 dbSNP
rs1009415289 292 dbSNP
rs1428054932 293 dbSNP
rs1014983305 294 dbSNP
rs952174062 297 dbSNP
rs961513190 299 dbSNP
rs1469061566 304 dbSNP
rs117253896 306 dbSNP
rs1212170336 311 dbSNP
rs1023074569 312 dbSNP
rs919759331 316 dbSNP
rs952657902 322 dbSNP
rs1305323618 329 dbSNP
rs979969065 330 dbSNP
rs926967518 340 dbSNP
rs1369722634 345 dbSNP
rs989157508 350 dbSNP
rs938329679 354 dbSNP
rs558949644 367 dbSNP
rs1444390705 369 dbSNP
rs1305347984 373 dbSNP
rs1371393177 383 dbSNP
rs912941897 389 dbSNP
rs1352890559 393 dbSNP
rs1175547273 395 dbSNP
rs1454897043 397 dbSNP
rs761118176 399 dbSNP
rs1049442670 402 dbSNP
rs1218284550 405 dbSNP
rs1872193 406 dbSNP
rs544930729 409 dbSNP
rs1479931265 411 dbSNP
rs1257264936 412 dbSNP
rs1210928247 413 dbSNP
rs943504881 417 dbSNP
rs1308772921 423 dbSNP
rs1227491703 439 dbSNP
rs1040518527 440 dbSNP
rs902034483 447 dbSNP
rs1043281739 457 dbSNP
rs904680153 459 dbSNP
rs996455136 471 dbSNP
rs1314848532 475 dbSNP
rs142133025 477 dbSNP
rs1050644377 479 dbSNP
rs1172077264 488 dbSNP
rs1197208938 493 dbSNP
rs1364786991 494 dbSNP
rs558587252 494 dbSNP
rs1158769394 513 dbSNP
rs779483273 515 dbSNP
rs1260145238 517 dbSNP
rs1189253283 519 dbSNP
rs1485097222 520 dbSNP
rs890467618 533 dbSNP
rs887761850 536 dbSNP
rs973295028 538 dbSNP
rs1488971029 539 dbSNP
rs553517506 541 dbSNP
rs1008868383 559 dbSNP
rs1015427167 560 dbSNP
rs897950918 561 dbSNP
rs1293890403 563 dbSNP
rs994867130 566 dbSNP
rs1026798147 577 dbSNP
rs181151512 580 dbSNP
rs754229597 581 dbSNP
rs970124245 594 dbSNP
rs952522406 596 dbSNP
rs1171475948 600 dbSNP
rs1385894273 601 dbSNP
rs1158357371 607 dbSNP
rs575450693 612 dbSNP
rs1420468433 615 dbSNP
rs1166341217 619 dbSNP
rs1422907141 628 dbSNP
rs764961609 629 dbSNP
rs1464014691 631 dbSNP
rs555829700 634 dbSNP
rs1194649694 639 dbSNP
rs1350285217 643 dbSNP
rs956095555 644 dbSNP
rs184442355 646 dbSNP
rs1034236199 654 dbSNP
rs1291481099 660 dbSNP
rs1232650081 663 dbSNP
rs1332525543 665 dbSNP
rs1021977062 677 dbSNP
rs542662348 680 dbSNP
rs1363593399 681 dbSNP
rs959976685 689 dbSNP
rs985097951 693 dbSNP
rs910920055 696 dbSNP
rs1397209968 697 dbSNP
rs1326940718 716 dbSNP
rs943773265 721 dbSNP
rs1277003831 723 dbSNP
rs1392839793 727 dbSNP
rs1169161109 728 dbSNP
rs1371991813 731 dbSNP
rs1475486888 731 dbSNP
rs78400983 732 dbSNP
rs1455286191 733 dbSNP
rs1212794950 739 dbSNP
rs1253416645 739 dbSNP
rs1467087285 748 dbSNP
rs757944252 751 dbSNP
rs531477088 752 dbSNP
rs1340199712 753 dbSNP
rs543037274 756 dbSNP
rs1226494784 760 dbSNP
rs1275548917 762 dbSNP
rs1322718169 763 dbSNP
rs945808840 764 dbSNP
rs1047937268 768 dbSNP
rs1392725034 771 dbSNP
rs888034770 783 dbSNP
rs1410984245 787 dbSNP
rs1395203617 794 dbSNP
rs1165600636 800 dbSNP
rs942294794 801 dbSNP
rs145993597 806 dbSNP
rs532823340 808 dbSNP
rs926128450 813 dbSNP
rs1192788582 832 dbSNP
rs1452406991 833 dbSNP
rs746862719 837 dbSNP
rs1395018495 842 dbSNP
rs1486966154 843 dbSNP
rs138346674 844 dbSNP
rs932110098 863 dbSNP
rs1262580657 864 dbSNP
rs1476859612 865 dbSNP
rs1167043322 868 dbSNP
rs1203032202 877 dbSNP
rs1350344008 891 dbSNP
rs1414419462 897 dbSNP
rs1281391430 907 dbSNP
rs1233846136 911 dbSNP
rs1365975549 912 dbSNP
rs1281612167 915 dbSNP
rs1051130323 920 dbSNP
rs1162424958 928 dbSNP
rs1346655340 931 dbSNP
rs34912495 931 dbSNP
rs1305643850 933 dbSNP
rs1002942938 938 dbSNP
rs1042833 945 dbSNP
rs370727991 954 dbSNP
rs944952339 955 dbSNP
rs1297125776 956 dbSNP
rs1010487964 964 dbSNP
rs1158891106 968 dbSNP
rs1036400477 973 dbSNP
rs1231049485 982 dbSNP
rs1469569870 982 dbSNP
rs897800684 985 dbSNP
rs879034740 987 dbSNP
rs1380486152 1002 dbSNP
rs530318462 1005 dbSNP
rs1286816499 1008 dbSNP
rs1224617353 1010 dbSNP
rs1350605268 1015 dbSNP
rs188931848 1018 dbSNP
rs888286185 1019 dbSNP
rs1001284610 1020 dbSNP
rs1017883601 1026 dbSNP
rs1034594843 1031 dbSNP
rs1445400260 1033 dbSNP
rs960016796 1042 dbSNP
rs1346533397 1044 dbSNP
rs1318744971 1051 dbSNP
rs965027882 1053 dbSNP
rs182002144 1054 dbSNP
rs1285519671 1056 dbSNP
rs1019973504 1059 dbSNP
rs967011520 1062 dbSNP
rs1487378230 1063 dbSNP
rs1475479249 1064 dbSNP
rs1190121065 1065 dbSNP
rs1187258196 1071 dbSNP
rs1482400948 1073 dbSNP
rs1244001451 1074 dbSNP
rs866465950 1087 dbSNP
rs1216751951 1091 dbSNP
rs1238045524 1092 dbSNP
rs768911913 1098 dbSNP
rs925661037 1099 dbSNP
rs932142954 1100 dbSNP
rs1336056653 1106 dbSNP
rs537585686 1107 dbSNP
rs1179986756 1110 dbSNP
rs371437187 1119 dbSNP
rs1409894465 1127 dbSNP
rs774504143 1130 dbSNP
rs1157695513 1133 dbSNP
rs912041722 1134 dbSNP
rs1270482833 1136 dbSNP
rs1436085982 1144 dbSNP
rs1429560790 1149 dbSNP
rs1386240904 1160 dbSNP
rs1327608023 1161 dbSNP
rs748256153 1162 dbSNP
rs1164187937 1163 dbSNP
rs1422194058 1164 dbSNP
rs909423374 1170 dbSNP
rs772070328 1176 dbSNP
rs942240582 1181 dbSNP
rs897840645 1182 dbSNP
rs1246607024 1184 dbSNP
rs1447954553 1184 dbSNP
rs773331630 1186 dbSNP
rs1049137608 1187 dbSNP
rs187423088 1188 dbSNP
rs1273176477 1195 dbSNP
rs1220002610 1205 dbSNP
rs1308794781 1206 dbSNP
rs1379603514 1207 dbSNP
rs1241298587 1217 dbSNP
rs1002690186 1218 dbSNP
rs1376722483 1222 dbSNP
rs1362525817 1223 dbSNP
rs1305359720 1224 dbSNP
rs1441287605 1225 dbSNP
rs570527097 1231 dbSNP
rs538504178 1244 dbSNP
rs191786278 1245 dbSNP
rs1055659862 1246 dbSNP
rs1291781805 1247 dbSNP
rs1057177965 1254 dbSNP
rs1308856521 1256 dbSNP
rs1171178792 1257 dbSNP
rs1429355020 1259 dbSNP
rs891882291 1276 dbSNP
rs1351778557 1285 dbSNP
rs1455030547 1289 dbSNP
rs761155392 1295 dbSNP
rs572053851 1298 dbSNP
rs1213180765 1305 dbSNP
rs1279436793 1310 dbSNP
rs1014191273 1311 dbSNP
rs1020593101 1327 dbSNP
rs1251411155 1328 dbSNP
rs1203123229 1329 dbSNP
rs1282088069 1331 dbSNP
rs574662977 1331 dbSNP
rs542446063 1338 dbSNP
rs554781905 1339 dbSNP
rs904395499 1340 dbSNP
rs1346932349 1348 dbSNP
rs1234482621 1355 dbSNP
rs11048821 1358 dbSNP
rs1393100401 1362 dbSNP
rs1018165933 1364 dbSNP
rs559859993 1368 dbSNP
rs964975846 1375 dbSNP
rs17487041 1376 dbSNP
rs1175806989 1378 dbSNP
rs1025344374 1383 dbSNP
rs564843071 1392 dbSNP
rs1172735455 1394 dbSNP
rs532018067 1396 dbSNP
rs1421399648 1409 dbSNP
rs1251794856 1410 dbSNP
rs386761376 1410 dbSNP
rs1182068523 1412 dbSNP
rs1481824457 1415 dbSNP
rs532157350 1416 dbSNP
rs1211218093 1428 dbSNP
rs1332826493 1433 dbSNP
rs541700880 1436 dbSNP
rs180981049 1447 dbSNP
rs986273577 1449 dbSNP
rs530466172 1452 dbSNP
rs983909563 1455 dbSNP
rs1317281003 1461 dbSNP
rs1306280864 1467 dbSNP
rs912079569 1469 dbSNP
rs752331784 1473 dbSNP
rs1314770104 1481 dbSNP
rs966579089 1485 dbSNP
rs1415663390 1487 dbSNP
rs1401689625 1490 dbSNP
rs1331081201 1497 dbSNP
rs1375068475 1499 dbSNP
rs1301477317 1500 dbSNP
rs909357032 1505 dbSNP
rs1364735496 1507 dbSNP
rs963551137 1510 dbSNP
rs980323346 1511 dbSNP
rs1275620955 1518 dbSNP
rs1344422855 1540 dbSNP
rs1187965423 1542 dbSNP
rs1441499744 1546 dbSNP
rs1253712175 1554 dbSNP
rs548479950 1556 dbSNP
rs1206521312 1558 dbSNP
rs1217522662 1561 dbSNP
rs111936388 1563 dbSNP
rs1206762680 1565 dbSNP
rs1206979149 1567 dbSNP
rs146349232 1569 dbSNP
rs930893118 1573 dbSNP
rs765164439 1574 dbSNP
rs1233917771 1576 dbSNP
rs1339935553 1580 dbSNP
rs1049083325 1584 dbSNP
rs758282275 1594 dbSNP
rs1384106903 1597 dbSNP
rs1386194993 1598 dbSNP
rs1320251290 1600 dbSNP
rs1236144558 1603 dbSNP
rs1456116413 1608 dbSNP
rs913270749 1613 dbSNP
rs1469619431 1615 dbSNP
rs372628725 1619 dbSNP
rs1247454583 1626 dbSNP
rs570510603 1627 dbSNP
rs926612736 1627 dbSNP
rs938133046 1628 dbSNP
rs1428688918 1636 dbSNP
rs552261877 1638 dbSNP
rs185814501 1646 dbSNP
rs1165399759 1648 dbSNP
rs1391713794 1650 dbSNP
rs1273801446 1655 dbSNP
rs1405047682 1657 dbSNP
rs1056928898 1659 dbSNP
rs1321841583 1661 dbSNP
rs1327205636 1662 dbSNP
rs144222775 1662 dbSNP
rs565458718 1662 dbSNP
rs534693486 1663 dbSNP
rs1282623418 1669 dbSNP
rs546629225 1669 dbSNP
rs901092339 1669 dbSNP
rs998155001 1671 dbSNP
rs1041661559 1672 dbSNP
rs771307109 1672 dbSNP
rs1376126042 1675 dbSNP
rs903142629 1678 dbSNP
rs1285796067 1679 dbSNP
rs1389113234 1680 dbSNP
rs1000108541 1681 dbSNP
rs1032709578 1684 dbSNP
rs1287336835 1685 dbSNP
rs1016709479 1687 dbSNP
rs565621305 1687 dbSNP
rs980274350 1690 dbSNP
rs536573597 1698 dbSNP
rs1198778617 1702 dbSNP
rs1019075295 1703 dbSNP
rs1274271879 1703 dbSNP
rs755735481 1705 dbSNP
rs1438455371 1706 dbSNP
rs763568522 1707 dbSNP
rs1190032275 1711 dbSNP
rs1187794556 1715 dbSNP
rs1369351641 1718 dbSNP
rs1472694715 1719 dbSNP
rs960565613 1727 dbSNP
rs1402796202 1730 dbSNP
rs780418981 1734 dbSNP
rs1436427596 1737 dbSNP
rs1330842303 1741 dbSNP
rs1399442741 1744 dbSNP
rs1389547068 1745 dbSNP
rs1330327792 1746 dbSNP
rs1336098522 1747 dbSNP
rs1391525093 1757 dbSNP
rs749648279 1759 dbSNP
rs755409126 1768 dbSNP
rs779368769 1769 dbSNP
rs1319605838 1770 dbSNP
rs1218701366 1774 dbSNP
rs993118104 1775 dbSNP
rs1256927771 1777 dbSNP
rs972680885 1779 dbSNP
rs1395483771 1787 dbSNP
rs1202628047 1788 dbSNP
rs554437012 1792 dbSNP
rs1171741770 1794 dbSNP
rs1352397127 1795 dbSNP
rs1477002991 1801 dbSNP
rs531198396 1805 dbSNP
rs1185925366 1806 dbSNP
rs1303228591 1815 dbSNP
rs952326652 1817 dbSNP
rs1478304962 1818 dbSNP
rs1292562206 1824 dbSNP
rs1477186432 1826 dbSNP
rs1170622258 1827 dbSNP
rs1279784824 1834 dbSNP
rs796448365 1836 dbSNP
rs946088207 1836 dbSNP
rs561810792 1837 dbSNP
rs984989137 1839 dbSNP
rs926645479 1842 dbSNP
rs1229520541 1847 dbSNP
rs1281851138 1847 dbSNP
rs937981095 1848 dbSNP
rs576198453 1859 dbSNP
rs1305591194 1862 dbSNP
rs1459802449 1865 dbSNP
rs1195510813 1866 dbSNP
rs917956695 1867 dbSNP
rs945479823 1875 dbSNP
rs1390359443 1887 dbSNP
rs1412609414 1888 dbSNP
rs536709454 1897 dbSNP
rs1409847181 1900 dbSNP
rs1159124219 1907 dbSNP
rs1472194356 1909 dbSNP
rs1180015664 1911 dbSNP
rs12829295 1911 dbSNP
rs879878287 1921 dbSNP
rs138750315 1923 dbSNP
rs1238330760 1925 dbSNP
rs1341238573 1926 dbSNP
rs1399459166 1932 dbSNP
rs1441090453 1934 dbSNP
rs1039511642 1939 dbSNP
rs1209931116 1942 dbSNP
rs1329038411 1943 dbSNP
rs1285916117 1947 dbSNP
rs1234527913 1951 dbSNP
rs901038589 1953 dbSNP
rs935929813 1967 dbSNP
rs1054343375 1968 dbSNP
rs888792995 1969 dbSNP
rs1046985684 1970 dbSNP
rs1320929354 1976 dbSNP
rs1456642590 1983 dbSNP
rs886749247 1990 dbSNP
rs1007596864 1994 dbSNP
rs1005218212 1998 dbSNP
rs781165863 2008 dbSNP
rs1016658866 2010 dbSNP
rs1414591860 2015 dbSNP
rs36088737 2016 dbSNP
rs745681385 2017 dbSNP
rs769873925 2019 dbSNP
rs901622265 2022 dbSNP
rs1034497950 2029 dbSNP
rs1464851549 2035 dbSNP
rs960249364 2041 dbSNP
rs1216062531 2043 dbSNP
rs993193928 2046 dbSNP
rs73091125 2063 dbSNP
rs1218373811 2065 dbSNP
rs1286221832 2069 dbSNP
rs559425974 2071 dbSNP
rs967749576 2072 dbSNP
rs1298074122 2073 dbSNP
rs1434164398 2075 dbSNP
rs528871302 2077 dbSNP
rs1327896835 2078 dbSNP
rs1260342183 2079 dbSNP
rs542531442 2081 dbSNP
rs1350566153 2084 dbSNP
rs1033859436 2093 dbSNP
rs978727480 2093 dbSNP
rs1392194353 2099 dbSNP
rs925997237 2102 dbSNP
rs959404424 2116 dbSNP
rs1196077731 2117 dbSNP
rs149424842 2119 dbSNP
rs917918439 2120 dbSNP
rs1245627682 2121 dbSNP
rs945483478 2123 dbSNP
rs1218663352 2131 dbSNP
rs978154737 2133 dbSNP
rs975499428 2135 dbSNP
rs1274984763 2137 dbSNP
rs1227176176 2140 dbSNP
rs922409309 2146 dbSNP
rs1188782450 2156 dbSNP
rs924450791 2160 dbSNP
rs1047380876 2171 dbSNP
rs935783800 2182 dbSNP
rs1372481692 2185 dbSNP
rs1471987101 2186 dbSNP
rs1308917432 2199 dbSNP
rs1054374743 2200 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aaagaggaggguAGAAGGUGUg 5'
                      |:||||||| 
Target 5' ------ucaagcUUUUCCACAg 3'
 		1 - 16
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000282892.3 | 3UTR | UCAAGCUUUUCCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000282892.3 | 3UTR | UCAAGCUUUUCCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
85 hsa-miR-6833-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055111 SCD stearoyl-CoA desaturase 2 2
MIRT056784 ARID5B AT-rich interaction domain 5B 2 2
MIRT063833 SRP9 signal recognition particle 9 2 6
MIRT068906 TPRG1L tumor protein p63 regulated 1 like 2 2
MIRT087861 CBY1 chibby family member 1, beta catenin antagonist 2 4
MIRT102313 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT189645 AKAP11 A-kinase anchoring protein 11 2 2
MIRT191247 STYX serine/threonine/tyrosine interacting protein 2 2
MIRT195912 SRSF11 serine and arginine rich splicing factor 11 2 4
MIRT215291 CREBRF CREB3 regulatory factor 2 2
MIRT219058 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT240350 UBXN2B UBX domain protein 2B 2 2
MIRT244626 PLAG1 PLAG1 zinc finger 2 2
MIRT271181 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT277519 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT284544 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT286223 TMEM97 transmembrane protein 97 2 4
MIRT314185 OCLN occludin 2 4
MIRT336247 SKI SKI proto-oncogene 2 4
MIRT357689 PAIP2 poly(A) binding protein interacting protein 2 2 2
MIRT447422 MED21 mediator complex subunit 21 2 2
MIRT451274 ZNF101 zinc finger protein 101 2 2
MIRT453571 CRCP CGRP receptor component 2 2
MIRT454361 ASAH2 N-acylsphingosine amidohydrolase 2 2 2
MIRT460906 POLQ DNA polymerase theta 2 2
MIRT469362 REST RE1 silencing transcription factor 2 6
MIRT470269 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 2
MIRT471927 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT474227 LCLAT1 lysocardiolipin acyltransferase 1 2 2
MIRT480241 C8orf58 chromosome 8 open reading frame 58 2 2
MIRT480543 BZW1 basic leucine zipper and W2 domains 1 2 2
MIRT480924 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT497343 RPP25L ribonuclease P/MRP subunit p25 like 2 2
MIRT498824 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 8
MIRT498928 TMEM106B transmembrane protein 106B 2 8
MIRT499584 INTU inturned planar cell polarity protein 2 4
MIRT500118 ZNF106 zinc finger protein 106 2 4
MIRT500474 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT501717 OVOL1 ovo like transcriptional repressor 1 2 2
MIRT501908 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 4
MIRT502197 HSPB8 heat shock protein family B (small) member 8 2 2
MIRT505229 UBE2D3 ubiquitin conjugating enzyme E2 D3 2 2
MIRT505945 RAN RAN, member RAS oncogene family 2 6
MIRT507971 BCL2L13 BCL2 like 13 2 4
MIRT512251 ARPP19 cAMP regulated phosphoprotein 19 2 6
MIRT513024 GPT2 glutamic--pyruvic transaminase 2 2 2
MIRT530791 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT533403 TXLNG taxilin gamma 2 2
MIRT546728 RNF217 ring finger protein 217 2 2
MIRT554087 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 2
MIRT559924 SOD2 superoxide dismutase 2 2 2
MIRT560258 TMEM236 transmembrane protein 236 2 2
MIRT560412 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT560420 ANGPTL3 angiopoietin like 3 2 2
MIRT560495 KCNJ10 potassium voltage-gated channel subfamily J member 10 2 2
MIRT560549 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT560802 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT560883 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT560997 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT561090 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT561193 LDHD lactate dehydrogenase D 2 2
MIRT561835 NREP neuronal regeneration related protein 2 2
MIRT562393 EIF4E eukaryotic translation initiation factor 4E 2 2
MIRT568153 CCDC6 coiled-coil domain containing 6 2 2
MIRT572725 NUP188 nucleoporin 188 2 2
MIRT572886 ADCY2 adenylate cyclase 2 2 2
MIRT575747 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT606770 KIAA0040 KIAA0040 2 5
MIRT620360 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT623579 IREB2 iron responsive element binding protein 2 2 2
MIRT640726 PHF13 PHD finger protein 13 2 2
MIRT651579 WDR26 WD repeat domain 26 2 2
MIRT674927 C1orf116 chromosome 1 open reading frame 116 2 2
MIRT687378 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT687699 KRR1 KRR1, small subunit processome component homolog 2 2
MIRT693331 E2F2 E2F transcription factor 2 2 2
MIRT695289 TK1 thymidine kinase 1 2 2
MIRT697691 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT699810 SDHD succinate dehydrogenase complex subunit D 2 2
MIRT702280 LEPROT leptin receptor overlapping transcript 2 2
MIRT708498 FAM9C family with sequence similarity 9 member C 2 2
MIRT710101 HEY2 hes related family bHLH transcription factor with YRPW motif 2 2 2
MIRT717883 GBP4 guanylate binding protein 4 2 2
MIRT719248 MS4A1 membrane spanning 4-domains A1 2 2
MIRT719958 SAMD15 sterile alpha motif domain containing 15 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6833 Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-miR-6833-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-6833-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-6833-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-6833-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

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