miRTarBase - #MIRT448062


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pre-miRNA Information
pre-miRNA hsa-mir-3921   
Genomic Coordinates chr3: 99964314 - 99964398
Description Homo sapiens miR-3921 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3921
Sequence 52| UCUCUGAGUACCAUAUGCCUUGU |74
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN7769671 6 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs758695096 5 dbSNP
rs539077798 6 dbSNP
rs954620527 10 dbSNP
rs1437951547 17 dbSNP
Putative Targets

Gene Information
Gene Symbol MMP15   
Synonyms MMP-15, MT2-MMP, MT2MMP, MTMMP2, SMCP-2
Description matrix metallopeptidase 15
Transcript NM_002428   
Expression
Putative miRNA Targets on MMP15
3'UTR of MMP15
(miRNA target sites are highlighted)		 
>MMP15|NM_002428|3'UTR
   1 CCACCCAGCGCTCCTGCTAACGGTGCTCAGGGGGCGCCTGTGGTTCTGAGATGGCTCCCAGGGGCTCCCTCCGCCCCCAG
  81 GTAGGGGCCCCTCTCAGCCCTCACACACCCTGTCTGCCCCGCCCTCATTATTTATGTCCAGGTGTTTGTTTTGTTTTGTT
 161 TTTGGCACCTTACTTGACCATTTGTTTCTGTTTCCCCGACTGGGGCAGGGTGTTTAGAATTTTCTAAATGTAGTTCTGCT
 241 CCAGACAGGGAATTAGGCCCCCATCATCCTCTGGCTTGGCCACAGCCAGGGGAGCAGAGGGGCAGAGGCCCACATTGGAA
 321 GAGCAGCACCTCCTCAGCCTGAACCCCAGGGCTGTAACTGCCAGGCTCTCTTTGCCCAGTTGGAGACTGTCTGGCCCCCC
 401 TGGTCCCCTCCTTCCCAAGTGAGTCTCTCTGGGCCTTAGGAAGAGCCTTCCACCCAGGGGCAGCCCCAGGCCAAAGGGGA
 481 CCTGGAAGGGAGGTGGGCCGTGGCCCTTGAGTCCCCATTGAGGCTTGGTTCCTTCCCAATCCAGTGGACTTCGCAGTCCA
 561 CTTCTGACAGCCTCAGTGACCCTGGCTCCTTGTGCCAGAGAACCCAGCCCACCCCCGGCAGCAGCCCCCAGCTCCCACCT
 641 CCCCTTGGGCCCACACCTCCTTCCCTCTCTGGAGAAAGGGCCCTGGGCCTGCCTCACCACGGACCAAAGGGAGTCTGCCA
 721 GGGCCCCTCTCCCCAGGGAAGCAGCAGCCTCGCCCCTGGCAGAGATGCCTCCCTGAGCTAGAACCCTCTGTTCCTTCCCT
 801 GTGCCTCCTCCCTCCCTCTCCGACTCACACCACTAGCCTCAGGGGTCTGAGCTCCAGCTCCTTTGGGCTTCAGCTGCCAG
 881 TGTCCTGAGCCCCAGGGAGAGGGGGCTGGTGGGTGCCTAGGCCTGGGCAGTGGATGGCCGTGAATGGGTGCCCACAGTGT
 961 CAGGCACTGGGCATGAGGGGTTCCTCCCCTCCAGCTCCCTGTGCCCCCAGGGTCCTGGGAGGAGAGACACTGGTGGGGAT
1041 AGGCCAGCCGCGCATCAGACTGTGAACCCCACGAAGGAGCCCATTGTGGCCTAAGAGGCTGCCCTCCTGTGCTCAGCCCT
1121 GAGGACAGATGCCTCCTTCCTCTTTTCCTTCCCAAAGCAAGCAAGAGGCCGTGGCTGCTGTGGGAAATGGTACTGTACAG
1201 CTGGCTCTACTTCCCCATGGCCCTGAGCGAGTGGAGTCTGCCACCCAGGATCCCCAAGGCACTTGAGGGGGAAGGATTCT
1281 GCTGGCCTCTGCGAGTGGTTTCTTGTGCACTGGCACCAAGTGCGGGTCCGGCAGCTTCTGCCCCCTGCAGAACCGGAGAG
1361 CCAGCTAAGGGGTGGGGCTGCGGGGGTTCCGTGTCCACCCCCATACATTTATTTCTGTAAATAATGTGCACTGAATAAAT
1441 TGTACAGCCGGCAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uguucCGUAUACCAUGAGUCUCu 5'
               ||  | |||:|||||:| 
Target 5' ctcctGCTAACGGTGCTCAGGGg 3'
 11 - 33 146.00 -19.10
2 
miRNA  3' ugUUCC----GU-AUACCAUGAGUCUCu 5'
            ||||    || |:|||  || |||| 
Target 5' cgAAGGAGCCCATTGTGG-CCTAAGAGg 3'
 1072 - 1098 126.00 -13.10
3 
miRNA  3' uguuccguauaccauGAGUCUCu 5'
                         |||||:| 
Target 5' actcacaccactagcCTCAGGGg 3'
 823 - 845 124.00 -10.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30139944 26 COSMIC
COSN30119903 36 COSMIC
COSN22692918 430 COSMIC
COSN24965193 616 COSMIC
COSN6646343 660 COSMIC
COSN31590224 745 COSMIC
COSN31563467 779 COSMIC
COSN28768119 866 COSMIC
COSN31480889 888 COSMIC
COSN28740005 910 COSMIC
COSN25229767 1001 COSMIC
COSN21977552 1093 COSMIC
COSN31597604 1201 COSMIC
COSN24305496 1221 COSMIC
COSN30164616 1339 COSMIC
COSN24305758 1382 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs945775579 1 dbSNP
rs1329016786 3 dbSNP
rs768624058 6 dbSNP
rs1265153547 9 dbSNP
rs113877220 10 dbSNP
rs376623496 11 dbSNP
rs774334502 12 dbSNP
rs901711003 14 dbSNP
rs1481492752 15 dbSNP
rs1490085842 16 dbSNP
rs1241758265 19 dbSNP
rs368575241 19 dbSNP
rs1410935309 20 dbSNP
rs767772197 22 dbSNP
rs994682022 23 dbSNP
rs376333947 24 dbSNP
rs150382270 27 dbSNP
rs1413359550 33 dbSNP
rs766859508 34 dbSNP
rs761056257 36 dbSNP
rs41324945 37 dbSNP
rs1309084291 38 dbSNP
rs1363707379 52 dbSNP
rs1157499946 53 dbSNP
rs1327100219 59 dbSNP
rs993611100 61 dbSNP
rs1025047376 71 dbSNP
rs41496151 73 dbSNP
rs754219207 74 dbSNP
rs1218126035 79 dbSNP
rs988386494 81 dbSNP
rs1259650361 87 dbSNP
rs1269156132 89 dbSNP
rs1213504453 92 dbSNP
rs926877626 96 dbSNP
rs767142184 97 dbSNP
rs548639606 98 dbSNP
rs750059510 99 dbSNP
rs990239364 101 dbSNP
rs1280391955 106 dbSNP
rs914208135 108 dbSNP
rs1384298430 117 dbSNP
rs1214130838 121 dbSNP
rs570083279 122 dbSNP
rs975570805 125 dbSNP
rs923021782 128 dbSNP
rs1194812379 145 dbSNP
rs1426741190 145 dbSNP
rs1468605110 145 dbSNP
rs1428777514 148 dbSNP
rs138174529 150 dbSNP
rs1261888085 155 dbSNP
rs1484194677 157 dbSNP
rs553678533 161 dbSNP
rs1422707855 162 dbSNP
rs1050234109 163 dbSNP
rs889050381 164 dbSNP
rs1006110047 170 dbSNP
rs1228346156 184 dbSNP
rs879152832 185 dbSNP
rs1326088013 191 dbSNP
rs552173623 198 dbSNP
rs865870145 199 dbSNP
rs1384144497 201 dbSNP
rs1419607089 203 dbSNP
rs1468721028 205 dbSNP
rs931778348 206 dbSNP
rs1475301422 209 dbSNP
rs897853506 211 dbSNP
rs1372201642 218 dbSNP
rs1166116021 228 dbSNP
rs1051846466 230 dbSNP
rs1243246037 236 dbSNP
rs911599217 237 dbSNP
rs570762899 243 dbSNP
rs993496319 245 dbSNP
rs1459930830 251 dbSNP
rs1252336758 253 dbSNP
rs1291135802 261 dbSNP
rs1025101095 262 dbSNP
rs1196219336 269 dbSNP
rs534994342 276 dbSNP
rs1002788828 288 dbSNP
rs1247053735 290 dbSNP
rs553292764 293 dbSNP
rs1314493615 297 dbSNP
rs994650908 301 dbSNP
rs1379774944 302 dbSNP
rs1310615034 308 dbSNP
rs1044934311 315 dbSNP
rs755504845 316 dbSNP
rs765744394 318 dbSNP
rs1296045568 327 dbSNP
rs574688858 328 dbSNP
rs1287560302 329 dbSNP
rs1385243450 346 dbSNP
rs914135553 351 dbSNP
rs967055991 357 dbSNP
rs977048430 366 dbSNP
rs879024609 369 dbSNP
rs1035430423 373 dbSNP
rs1437065092 375 dbSNP
rs1326797308 386 dbSNP
rs933045438 388 dbSNP
rs1490575343 389 dbSNP
rs892432347 396 dbSNP
rs1243941394 398 dbSNP
rs910414607 399 dbSNP
rs941840093 400 dbSNP
rs1334311920 401 dbSNP
rs535698710 402 dbSNP
rs1009526159 408 dbSNP
rs1022479101 416 dbSNP
rs1406334047 417 dbSNP
rs1365875138 418 dbSNP
rs1301985414 424 dbSNP
rs1422256851 424 dbSNP
rs574918399 441 dbSNP
rs975538191 442 dbSNP
rs1198250489 446 dbSNP
rs897739693 447 dbSNP
rs1361776956 451 dbSNP
rs1028511963 454 dbSNP
rs1201330922 459 dbSNP
rs953243041 470 dbSNP
rs1268529320 479 dbSNP
rs1046392729 483 dbSNP
rs987274813 500 dbSNP
rs1285086487 501 dbSNP
rs41399651 503 dbSNP
rs1002263761 508 dbSNP
rs1285570554 511 dbSNP
rs1181005473 512 dbSNP
rs1224580019 515 dbSNP
rs1345716401 518 dbSNP
rs41411446 519 dbSNP
rs971744644 524 dbSNP
rs1402741681 528 dbSNP
rs1161970817 538 dbSNP
rs147191739 540 dbSNP
rs1011488240 541 dbSNP
rs930575835 546 dbSNP
rs1045284506 553 dbSNP
rs905065258 554 dbSNP
rs939188478 559 dbSNP
rs1465937184 561 dbSNP
rs966898156 562 dbSNP
rs1056511709 565 dbSNP
rs1476517729 566 dbSNP
rs1242720681 571 dbSNP
rs1192640865 572 dbSNP
rs1377284977 574 dbSNP
rs892568899 575 dbSNP
rs977058232 581 dbSNP
rs1204688964 587 dbSNP
rs1009494886 589 dbSNP
rs1225286163 591 dbSNP
rs1292087932 599 dbSNP
rs1022279869 604 dbSNP
rs1270253723 612 dbSNP
rs780522482 612 dbSNP
rs1429493059 613 dbSNP
rs904092573 614 dbSNP
rs997092594 617 dbSNP
rs375862058 618 dbSNP
rs573136401 626 dbSNP
rs540527389 629 dbSNP
rs910292378 630 dbSNP
rs1411853677 635 dbSNP
rs62041802 645 dbSNP
rs973200475 651 dbSNP
rs1335595232 653 dbSNP
rs955535644 656 dbSNP
rs929186335 657 dbSNP
rs1241621134 659 dbSNP
rs11076213 660 dbSNP
rs1018674838 663 dbSNP
rs961806303 665 dbSNP
rs755989583 668 dbSNP
rs1213452823 679 dbSNP
rs971710613 680 dbSNP
rs937990641 687 dbSNP
rs1316543441 696 dbSNP
rs1204068000 701 dbSNP
rs1055252891 702 dbSNP
rs893873425 704 dbSNP
rs1444164381 708 dbSNP
rs1249129529 710 dbSNP
rs920281968 716 dbSNP
rs1328382191 726 dbSNP
rs1428096261 730 dbSNP
rs1011037277 749 dbSNP
rs930544720 753 dbSNP
rs1164309826 754 dbSNP
rs1444544869 755 dbSNP
rs980747767 761 dbSNP
rs1383994408 768 dbSNP
rs1179284494 786 dbSNP
rs1179343798 788 dbSNP
rs1251619834 789 dbSNP
rs926535358 789 dbSNP
rs939174084 790 dbSNP
rs1056714144 798 dbSNP
rs1030308782 804 dbSNP
rs140020869 807 dbSNP
rs544089085 809 dbSNP
rs945485607 812 dbSNP
rs1017363162 813 dbSNP
rs963423096 816 dbSNP
rs1352995191 817 dbSNP
rs1031780988 818 dbSNP
rs1298534566 819 dbSNP
rs1366636778 822 dbSNP
rs1043702718 823 dbSNP
rs1303829522 825 dbSNP
rs1305514640 829 dbSNP
rs1348030479 834 dbSNP
rs1161847450 839 dbSNP
rs1227077973 841 dbSNP
rs919062531 844 dbSNP
rs929109282 860 dbSNP
rs982047158 861 dbSNP
rs779768648 862 dbSNP
rs1050779 866 dbSNP
rs530910320 886 dbSNP
rs1049972004 887 dbSNP
rs891392322 888 dbSNP
rs1263204101 891 dbSNP
rs1008369345 894 dbSNP
rs1204698852 899 dbSNP
rs1015799112 905 dbSNP
rs1283278078 906 dbSNP
rs1317458484 906 dbSNP
rs1252327593 907 dbSNP
rs961772283 914 dbSNP
rs1347581244 926 dbSNP
rs993286845 926 dbSNP
rs1284220462 928 dbSNP
rs1027317186 938 dbSNP
rs552110620 940 dbSNP
rs1365500380 941 dbSNP
rs1290728512 951 dbSNP
rs980862763 954 dbSNP
rs41388349 960 dbSNP
rs1455048319 967 dbSNP
rs149584196 968 dbSNP
rs998308326 973 dbSNP
rs1199645947 975 dbSNP
rs991985131 976 dbSNP
rs913774037 979 dbSNP
rs890002499 984 dbSNP
rs1007230193 986 dbSNP
rs1187822490 998 dbSNP
rs546868183 1002 dbSNP
rs768512372 1004 dbSNP
rs1017667230 1005 dbSNP
rs945454629 1010 dbSNP
rs1206560347 1019 dbSNP
rs1122306 1023 dbSNP
rs994614998 1025 dbSNP
rs1026048469 1033 dbSNP
rs1310726802 1034 dbSNP
rs950568276 1042 dbSNP
rs1459651588 1043 dbSNP
rs771014956 1050 dbSNP
rs927910526 1051 dbSNP
rs1455086335 1057 dbSNP
rs1407216002 1058 dbSNP
rs1176179049 1061 dbSNP
rs1371669766 1071 dbSNP
rs932646219 1073 dbSNP
rs536014148 1074 dbSNP
rs891367295 1076 dbSNP
rs748199428 1078 dbSNP
rs1246901151 1080 dbSNP
rs1428639730 1080 dbSNP
rs1008919972 1085 dbSNP
rs915198372 1087 dbSNP
rs772099003 1088 dbSNP
rs1243518553 1091 dbSNP
rs1311528715 1099 dbSNP
rs1319509162 1104 dbSNP
rs1482383814 1105 dbSNP
rs773426113 1117 dbSNP
rs557294607 1118 dbSNP
rs1228460231 1130 dbSNP
rs568889780 1132 dbSNP
rs1248731528 1136 dbSNP
rs1384257095 1141 dbSNP
rs1336479415 1142 dbSNP
rs1394694415 1143 dbSNP
rs1399576496 1150 dbSNP
rs1299473408 1164 dbSNP
rs897363532 1171 dbSNP
rs539550012 1172 dbSNP
rs1166239689 1174 dbSNP
rs1469305248 1175 dbSNP
rs557928662 1176 dbSNP
rs1385835551 1178 dbSNP
rs1240487640 1183 dbSNP
rs760827342 1184 dbSNP
rs1421783082 1185 dbSNP
rs572875140 1195 dbSNP
rs764925239 1199 dbSNP
rs1482860720 1202 dbSNP
rs1272554214 1206 dbSNP
rs1001864687 1216 dbSNP
rs1360755252 1218 dbSNP
rs1187372819 1225 dbSNP
rs1033787075 1229 dbSNP
rs1308163397 1229 dbSNP
rs960651590 1230 dbSNP
rs1305612276 1231 dbSNP
rs890064402 1243 dbSNP
rs1007526602 1245 dbSNP
rs1365684099 1246 dbSNP
rs1162545595 1252 dbSNP
rs1471772850 1254 dbSNP
rs1365268978 1261 dbSNP
rs1038602621 1266 dbSNP
rs898852892 1267 dbSNP
rs994500436 1268 dbSNP
rs950412921 1272 dbSNP
rs1289279851 1274 dbSNP
rs1394860950 1277 dbSNP
rs1050792 1280 dbSNP
rs1456704150 1282 dbSNP
rs1208501702 1290 dbSNP
rs992517075 1293 dbSNP
rs564141079 1294 dbSNP
rs1349475890 1298 dbSNP
rs1286023406 1299 dbSNP
rs1430863576 1306 dbSNP
rs555663405 1317 dbSNP
rs41523344 1322 dbSNP
rs879055432 1324 dbSNP
rs1322324119 1325 dbSNP
rs776901067 1330 dbSNP
rs759922674 1331 dbSNP
rs1158896231 1341 dbSNP
rs1456552276 1345 dbSNP
rs932759411 1346 dbSNP
rs765685450 1350 dbSNP
rs753211634 1355 dbSNP
rs944296040 1356 dbSNP
rs924032200 1361 dbSNP
rs1037253183 1367 dbSNP
rs934056048 1372 dbSNP
rs1263112679 1373 dbSNP
rs1216622656 1375 dbSNP
rs1208679529 1378 dbSNP
rs897429043 1382 dbSNP
rs573872592 1383 dbSNP
rs1048622810 1385 dbSNP
rs1345354069 1387 dbSNP
rs544344866 1391 dbSNP
rs866185153 1392 dbSNP
rs1039062941 1393 dbSNP
rs1156549963 1394 dbSNP
rs562550928 1399 dbSNP
rs1033340364 1401 dbSNP
rs1434314987 1404 dbSNP
rs1386092298 1410 dbSNP
rs1178335556 1412 dbSNP
rs898739955 1421 dbSNP
rs1424778337 1430 dbSNP
rs1170875179 1432 dbSNP
rs1476406757 1439 dbSNP
rs533193488 1450 dbSNP
rs1047388240 1451 dbSNP
rs1013205636 1452 dbSNP
rs1020806718 1453 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ugUUCCGUAUACCAUGAGUCUcu 5'
            ||| | |    | ||||||  
Target 5' ucAAGCCCU----UCCUCAGA-- 3'
 		1 - 17
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000219271.3 | 3UTR | UCAAGCCCUUCCUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000219271.3 | 3UTR | UCAAGCCCUUCCUCAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
77 hsa-miR-3921 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT118184 ZNF544 zinc finger protein 544 2 2
MIRT332934 PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 2 2
MIRT442165 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT442388 CLVS2 clavesin 2 2 2
MIRT442594 SIX1 SIX homeobox 1 2 2
MIRT448015 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT448062 MMP15 matrix metallopeptidase 15 2 2
MIRT489018 C1QTNF6 C1q and TNF related 6 2 2
MIRT494457 BTG2 BTG anti-proliferation factor 2 2 2
MIRT495651 SLC35B2 solute carrier family 35 member B2 2 2
MIRT504018 ACSL6 acyl-CoA synthetase long chain family member 6 2 2
MIRT506778 KLHL15 kelch like family member 15 2 4
MIRT507230 FOXN2 forkhead box N2 2 4
MIRT512551 MFN2 mitofusin 2 2 6
MIRT512843 A1CF APOBEC1 complementation factor 2 6
MIRT513943 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT516104 GADL1 glutamate decarboxylase like 1 2 4
MIRT519832 ZFP69B ZFP69 zinc finger protein B 2 4
MIRT523209 HIST1H3E histone cluster 1 H3 family member e 2 2
MIRT525007 ACTN4 actinin alpha 4 2 6
MIRT528859 PKP1 plakophilin 1 2 2
MIRT529061 ZNF675 zinc finger protein 675 2 2
MIRT531720 TARS threonyl-tRNA synthetase 2 2
MIRT534038 STK4 serine/threonine kinase 4 2 2
MIRT543849 APIP APAF1 interacting protein 2 2
MIRT545865 ZNF264 zinc finger protein 264 2 4
MIRT556038 MXD1 MAX dimerization protein 1 2 2
MIRT561346 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT562706 ZNF415 zinc finger protein 415 2 2
MIRT563224 ZNF286A zinc finger protein 286A 2 2
MIRT563861 ZNF616 zinc finger protein 616 2 4
MIRT563880 PAGR1 PAXIP1 associated glutamate rich protein 1 2 2
MIRT564653 ZNF487P zinc finger protein 487 1 1
MIRT566596 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT570879 ZFP1 ZFP1 zinc finger protein 2 2
MIRT573069 TRIB1 tribbles pseudokinase 1 2 2
MIRT573940 ZNF708 zinc finger protein 708 2 2
MIRT575967 Slfn5 schlafen 5 2 5
MIRT607294 CD300E CD300e molecule 2 4
MIRT608188 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT609538 ADPRH ADP-ribosylarginine hydrolase 2 2
MIRT610153 PRMT8 protein arginine methyltransferase 8 2 4
MIRT611572 SLFN5 schlafen family member 5 2 7
MIRT613336 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT616561 ZNF512B zinc finger protein 512B 2 2
MIRT617239 SPATS2 spermatogenesis associated serine rich 2 2 2
MIRT618012 SLC9A3R2 SLC9A3 regulator 2 2 2
MIRT618479 IL17REL interleukin 17 receptor E like 2 2
MIRT619100 IFI44L interferon induced protein 44 like 2 2
MIRT622266 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT623081 NME6 NME/NM23 nucleoside diphosphate kinase 6 2 2
MIRT625622 LILRB2 leukocyte immunoglobulin like receptor B2 2 2
MIRT627845 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT630460 GMPS guanine monophosphate synthase 2 2
MIRT630525 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 4
MIRT631503 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT634538 MRPS17 mitochondrial ribosomal protein S17 2 2
MIRT638808 DCTN3 dynactin subunit 3 2 2
MIRT641304 SLAMF1 signaling lymphocytic activation molecule family member 1 2 2
MIRT648348 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT649706 ZNF175 zinc finger protein 175 2 2
MIRT652555 TLX1 T-cell leukemia homeobox 1 2 2
MIRT655563 P2RX7 purinergic receptor P2X 7 2 2
MIRT659066 DEPTOR DEP domain containing MTOR interacting protein 2 2
MIRT660342 BCAT1 branched chain amino acid transaminase 1 2 2
MIRT664331 RAB8A RAB8A, member RAS oncogene family 2 2
MIRT688935 ATXN7L3B ataxin 7 like 3B 2 2
MIRT689972 ZNF185 zinc finger protein 185 with LIM domain 2 2
MIRT699515 SKIL SKI like proto-oncogene 2 2
MIRT699976 RREB1 ras responsive element binding protein 1 2 2
MIRT702675 IRS2 insulin receptor substrate 2 2 2
MIRT709358 ULK2 unc-51 like autophagy activating kinase 2 2 2
MIRT709838 PAQR7 progestin and adipoQ receptor family member 7 2 2
MIRT718717 ANKRD18A ankyrin repeat domain 18A 2 2
MIRT718880 PDIA3 protein disulfide isomerase family A member 3 2 2
MIRT724106 TMEM199 transmembrane protein 199 2 2
MIRT724764 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3921 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3921 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC7901)
hsa-miR-3921 Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-3921 Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-3921 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-3921 Tamoxifen+Fulvestrant sensitive cell line (LCC9)
hsa-miR-3921 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-3921 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3921 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)

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