miRTarBase - #MIRT448135


—
pre-miRNA Information
pre-miRNA hsa-mir-2681   
Genomic Coordinates chr13: 101967642 - 101967746
Description Homo sapiens miR-2681 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-2681-5p
Sequence 22| GUUUUACCACCUCCAGGAGACU |43
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 6 13 - 101967720 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1263364397 4 dbSNP
rs1184634146 7 dbSNP
rs1464264801 10 dbSNP
rs1173765682 11 dbSNP
rs1263470724 12 dbSNP
rs906180025 15 dbSNP
rs935390707 20 dbSNP
rs1045157564 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CMTM6   
Synonyms CKLFSF6, PRO2219
Description CKLF like MARVEL transmembrane domain containing 6
Transcript NM_017801   
Expression
Putative miRNA Targets on CMTM6
3'UTR of CMTM6
(miRNA target sites are highlighted)		 
>CMTM6|NM_017801|3'UTR
   1 AGACTCTGGGGAGCAGATGTTACCTAAGGTAGTGACCCTGCATTGTGGTGCCTGAGCCCTGGCAGAAGCTCTTGTAAAAT
  81 TTGTTAATTGTTTAAACCACTTCTTTTGGAGAGCAAGGGGAAGGTCAAGAAGGCAGTTTTATCAATATTGTGTCAGTCAC
 161 CACAAAGTAGGCCAGATAAGTTAAAAAAAATTTTTTTTTAAATAATAATTGAAACTTATCTCAAATGGAGATTTTGGTGG
 241 GAGGAGGAGAAAACAATTGTTTTTAAATCACACAGCTCAACGGTTGATAAATGATTCTGTCATTCTGTTACAGGTCATTC
 321 TTTTACTAGGCTTAGCTTCCAAATTATGCTTTATAGCTGTATAAACATCGTGATTATATTCATCTACTTAGAAATTGTTT
 401 TATTTTTAAATTAATTTGCTTAGCTGTTTGTTTTGATGCTTAGATTATGTTCTGTTAATGGGAATTTAACATATTTAAGA
 481 AACCAATATTTAAAATGTTGGTCTAGGTTTTTTTCCTTAACATATATTACCAGGCTTTACTGTATTTCACTCAGCCTTAA
 561 ATGTTATAATATTTTTGGATAACGGTTATTAATTCTTTGAGACCTTCGTATAGCCTATAAAATGTATGGGAGATGTTGGT
 641 ATTTTATGTGTATAAAAGCAACAATATCAGCAACTTCGTGTTTATACTGCACCTTGGTTGTTGATGTCAAGTAAAAAAAA
 721 GATTGTTTTGTAACACATAAAAAAATGGAAGAAACTGATACCACACCTAAGGACCAAAGATAAGAAAGACTTTTTGCCCA
 801 AGACAGTGAAAGTAATTATAAAAACAAGCTTTGACCACTTACCAAGTATCTGAAGAGATGAGTTCATACTATGATTTAGA
 881 AAGTGGTTCAATTCCCCTGTTGGCATATGATTATTTTTACTAAAATTAATACAGCTCTGTGGGTCTTCCTTAGTGTTTTC
 961 TTTGAAGCCAATCTGTTTTTTTTAGGACACCAGCCTTTGGTTTTTCATCTGTTCGAGATGCCTCTTCTCTGTCTCCTTAT
1041 CAGATAGAAATGGAGTCATGTGCTGCTGCTTCATCTAGCAGAGGTTGGCCTCTGGCTCTGACACTTTTTGTCAGTTGTCT
1121 TTAGGTGGTCCTGAATCTTGGGCCCTTTTGATTGTGAATACTGTGTAGCAGGATCTTGAGAGTCCTTGTTCTTACATAGG
1201 CATTGCTCTAGTTTGTCTTTGGCAAAAAAAAAAAAAAAAAAAAGTAAATATCCAGGGAACCCTGCCCAGACTAATACTGT
1281 TGGTGGCATAAGAGAATCAAGCCATTCTCAAGAGATAACTTCATAACCAGAATTGTCTGTTGGCTAGCAGCTGTCACAGA
1361 TAGGCAGGGCACTTGGGATATGACCTTTCTGTCCAGGTGATTCACAGACTAGACCTTTCTTATCCTCCTCCTAGAGTTTT
1441 GACTTGGGACTCTAGTGTTAAGATGATGAGCCCGTGCATCAGGTCCTTCTGCACTTTGGTGGAAGTCTCCCAGGGTAGGT
1521 TTCCTATTTGAAACAGTGGAATCATGTTTCCAGTGATAAAGTTTAATGACCTCATCCTTTTTTTTTTTTCTCATCTGCCA
1601 TTTGTGTGTCTTAGATGGGTTTTAATTGCATGAATGTGGCTAATGTGGTTCTCAGAAATTGGTCAGTATGGCCCAACATA
1681 GCTTCTGCTCTGTCTTACTGACTCAATACCTTTAGGATTTGTATCAGAGTTTGGATACTAGTGTTAGTGGTGGTGTCACC
1761 ACTACTTAATTGGGAGATAATGAAACCAATCATGGATGCTGTTTTTATTGGGCATGTCATCTAAGAGAGGAGAAATAGCT
1841 GGGTTTTGGGTCTAATTATGAATAAGGACTGATTCAGAAAACGAGTTTATGGTAGGTAGACTAAAGTTTCACATCAGACT
1921 GTACCATTGTGATTTAGACCTATCTAAAATTCAGAGCATATCATCTGGGCTACCTCAGGGTCACCACCCATGTATTGGGC
2001 TTAGTCAGGATTGACAGATACATTCTCAGCTGGCCTGTCATATAAAACATACTGTCATTGAGCTTAAGCTCCGCTTGTTC
2081 TGAGGTTTCACCTCCATGTGTTTCATTGGTGCAAAAGTGGATCTCTTAGTTGGTCACTTAATTCTTTCTTTTTCAGAAAG
2161 ATAGTATGTTCACTGGTATATTTGGTCACTCTTAGAACCTTCCTTCACATTGTTTTTTATGGGACCCATGAATGGTTAGC
2241 CTTTCTTTTCTATTGTAGAAGGAAATAAATAGGAGTAAAAAGACCATTGTAGTAAATAAGTTCAAGGGGAACTTGGGACC
2321 AGAAACCACTGTTATGTACAAAAAAATGGCAAATTCAATAAACTCAAATTTAAAATAATTTTTAAATTAACAGTTATGAT
2401 AAATTTTATATTTTATACAAATAGATTGCTTAGAATGGTTCTCAAGAATTATAAGAGAAATGAACTCACAGTACAAAAAT
2481 TTTATAATTACTATACTTGTGTTTTGTTTGGGGGCTGGGAAATGTATTTTTACATTGTAGCCAATCATTTTATATTTGTC
2561 AATTTAAATCTTATGGGTCTTTTTTTTTTATCTCTCTTGATGTCAGATTTTATAGTCTTTTTAAATAAATCCATTTAATT
2641 AAAACGTTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucaGAGGACCU-CCACCAUUUUg 5'
             ||:||| |   ||||::|| 
Target 5' gtcCTTCTGCACTTTGGTGGAAg 3'
 1483 - 1505 127.00 -12.70
2 
miRNA  3' ucagaGGACC-UC--C---ACCAUUUUg 5'
               ||||| ||  |   | |||||| 
Target 5' tgagcCCTGGCAGAAGCTCTTGTAAAAt 3'
 53 - 80 123.00 -9.90
3 
miRNA  3' ucagaggaccuccacCAUUUUg 5'
                         |||||| 
Target 5' ggttgttgatgtcaaGTAAAAa 3'
 696 - 717 120.00 -5.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30503578 8 COSMIC
COSN30492803 17 COSMIC
COSN30459316 24 COSMIC
COSN31505950 48 COSMIC
COSN28863071 62 COSMIC
COSN31524809 76 COSMIC
COSN6765877 87 COSMIC
COSN31610152 182 COSMIC
COSN31599986 187 COSMIC
COSN31567066 190 COSMIC
COSN31546211 191 COSMIC
COSN26193279 449 COSMIC
COSN31608244 677 COSMIC
COSN31535605 686 COSMIC
COSN1275992 976 COSMIC
COSN31530559 1014 COSMIC
COSN25866811 1015 COSMIC
COSN20120094 1043 COSMIC
COSN29002250 1095 COSMIC
COSN25803117 1223 COSMIC
COSN1946550 1516 COSMIC
COSN32063228 1668 COSMIC
COSN17408182 1910 COSMIC
COSN21955023 2053 COSMIC
COSN16476477 2058 COSMIC
COSN29021089 2075 COSMIC
COSN20098265 2579 COSMIC
COSN20098267 2580 COSMIC
COSN27724420 2589 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1455574687 3 dbSNP
rs982767648 7 dbSNP
rs951383881 10 dbSNP
rs777909627 11 dbSNP
rs369965860 13 dbSNP
rs769315649 13 dbSNP
rs919943551 14 dbSNP
rs1187110976 19 dbSNP
rs770139169 23 dbSNP
rs890439195 24 dbSNP
rs748651747 31 dbSNP
rs1235838886 35 dbSNP
rs1188423605 36 dbSNP
rs376753786 36 dbSNP
rs1318980713 40 dbSNP
rs1486226693 42 dbSNP
rs973957561 44 dbSNP
rs958881709 54 dbSNP
rs1436917619 60 dbSNP
rs193223960 63 dbSNP
rs1270257835 65 dbSNP
rs1377873493 83 dbSNP
rs1226504755 90 dbSNP
rs563907278 93 dbSNP
rs1251719811 102 dbSNP
rs996640917 105 dbSNP
rs981722406 109 dbSNP
rs1316059243 111 dbSNP
rs545753026 113 dbSNP
rs1039479349 116 dbSNP
rs1216842703 121 dbSNP
rs1236950059 131 dbSNP
rs1020023375 146 dbSNP
rs1415256660 149 dbSNP
rs1183697423 154 dbSNP
rs1419142049 159 dbSNP
rs1009841242 161 dbSNP
rs892773633 170 dbSNP
rs1157394460 171 dbSNP
rs1391360788 176 dbSNP
rs1402063601 177 dbSNP
rs1047417432 179 dbSNP
rs1032646322 190 dbSNP
rs1355930368 191 dbSNP
rs1445107489 191 dbSNP
rs878525 191 dbSNP
rs900120825 193 dbSNP
rs1286208305 196 dbSNP
rs190289471 199 dbSNP
rs1278127960 200 dbSNP
rs200527642 200 dbSNP
rs944232817 200 dbSNP
rs1212251339 210 dbSNP
rs958185014 218 dbSNP
rs1180709682 219 dbSNP
rs1031280472 227 dbSNP
rs891197964 238 dbSNP
rs115861303 241 dbSNP
rs573891696 244 dbSNP
rs1470693525 247 dbSNP
rs1172382481 251 dbSNP
rs774694609 252 dbSNP
rs769210642 256 dbSNP
rs1423957210 264 dbSNP
rs1412403143 274 dbSNP
rs368514833 281 dbSNP
rs954750561 287 dbSNP
rs185856781 296 dbSNP
rs1420406790 297 dbSNP
rs1166318139 299 dbSNP
rs1352284598 307 dbSNP
rs749798079 310 dbSNP
rs1255549938 311 dbSNP
rs919892174 311 dbSNP
rs1343134539 316 dbSNP
rs996284109 324 dbSNP
rs1281102440 326 dbSNP
rs537331932 349 dbSNP
rs937273657 358 dbSNP
rs570354846 359 dbSNP
rs3773778 362 dbSNP
rs1005378040 366 dbSNP
rs756238861 367 dbSNP
rs1476828031 369 dbSNP
rs1175174010 370 dbSNP
rs1395125837 384 dbSNP
rs1428490091 387 dbSNP
rs1456286264 392 dbSNP
rs888269821 401 dbSNP
rs1046999777 403 dbSNP
rs1391963634 407 dbSNP
rs971229939 408 dbSNP
rs929861398 410 dbSNP
rs1020085594 418 dbSNP
rs1443340452 422 dbSNP
rs988483640 423 dbSNP
rs73068767 426 dbSNP
rs1334032550 434 dbSNP
rs1276869067 439 dbSNP
rs1340669175 442 dbSNP
rs1281981415 458 dbSNP
rs1209826601 461 dbSNP
rs565944199 471 dbSNP
rs1335767352 477 dbSNP
rs916365537 479 dbSNP
rs1053519895 482 dbSNP
rs936846868 484 dbSNP
rs924080606 486 dbSNP
rs996278449 497 dbSNP
rs1389276242 504 dbSNP
rs1462415235 509 dbSNP
rs1397186708 512 dbSNP
rs531305612 515 dbSNP
rs1388531729 522 dbSNP
rs1461427001 524 dbSNP
rs547909602 526 dbSNP
rs1326348739 531 dbSNP
rs34512893 535 dbSNP
rs1160434251 540 dbSNP
rs1364641552 540 dbSNP
rs1433250732 550 dbSNP
rs1297793738 558 dbSNP
rs1470555067 561 dbSNP
rs1327149130 569 dbSNP
rs781512389 579 dbSNP
rs1363239325 583 dbSNP
rs1282897167 584 dbSNP
rs1018965866 585 dbSNP
rs1179954149 593 dbSNP
rs529450617 602 dbSNP
rs1464152244 607 dbSNP
rs116458700 608 dbSNP
rs1254701571 610 dbSNP
rs964675568 618 dbSNP
rs891271156 624 dbSNP
rs1476148389 633 dbSNP
rs1006245231 635 dbSNP
rs542231045 638 dbSNP
rs1468031541 646 dbSNP
rs573998226 650 dbSNP
rs1385982455 657 dbSNP
rs1395470836 658 dbSNP
rs1206764801 659 dbSNP
rs1332283343 662 dbSNP
rs1357915193 668 dbSNP
rs550026519 680 dbSNP
rs1350796259 683 dbSNP
rs1025863226 684 dbSNP
rs898622009 698 dbSNP
rs751425156 704 dbSNP
rs1327581379 708 dbSNP
rs937369329 711 dbSNP
rs1237565215 713 dbSNP
rs1372703715 717 dbSNP
rs1486602968 721 dbSNP
rs994099060 721 dbSNP
rs1188631327 723 dbSNP
rs1410910537 724 dbSNP
rs927216938 726 dbSNP
rs749265124 730 dbSNP
rs879236623 732 dbSNP
rs1440620223 734 dbSNP
rs1161046437 735 dbSNP
rs1364538219 738 dbSNP
rs879770327 740 dbSNP
rs3821700 745 dbSNP
rs1046302634 746 dbSNP
rs1320863752 752 dbSNP
rs1011947815 765 dbSNP
rs894793861 766 dbSNP
rs949976566 767 dbSNP
rs1349200070 777 dbSNP
rs1053551873 781 dbSNP
rs936376242 783 dbSNP
rs758203730 787 dbSNP
rs564375190 790 dbSNP
rs545790469 797 dbSNP
rs1384386313 799 dbSNP
rs924141058 805 dbSNP
rs1211012630 808 dbSNP
rs1250918985 812 dbSNP
rs913025919 812 dbSNP
rs1178727332 816 dbSNP
rs1251049576 820 dbSNP
rs933502163 845 dbSNP
rs148774752 850 dbSNP
rs957109777 862 dbSNP
rs1435367303 871 dbSNP
rs974954913 872 dbSNP
rs964706457 873 dbSNP
rs925722270 882 dbSNP
rs909195954 886 dbSNP
rs559940208 891 dbSNP
rs1385842176 899 dbSNP
rs541516743 903 dbSNP
rs1018625680 905 dbSNP
rs1234305293 906 dbSNP
rs1273373987 910 dbSNP
rs1305682917 914 dbSNP
rs752715866 922 dbSNP
rs1251646148 932 dbSNP
rs1488012851 935 dbSNP
rs1191541933 941 dbSNP
rs994439376 944 dbSNP
rs574228399 955 dbSNP
rs1008450841 957 dbSNP
rs955612422 959 dbSNP
rs1417532454 960 dbSNP
rs1430789245 968 dbSNP
rs1171775599 970 dbSNP
rs1024919978 973 dbSNP
rs1456666017 973 dbSNP
rs1447484384 976 dbSNP
rs1025816581 983 dbSNP
rs1012145564 984 dbSNP
rs1296204313 984 dbSNP
rs894826456 988 dbSNP
rs555520608 989 dbSNP
rs1296145994 994 dbSNP
rs1213814641 995 dbSNP
rs1000620601 999 dbSNP
rs902300940 1000 dbSNP
rs1042133104 1007 dbSNP
rs1208400845 1011 dbSNP
rs543581470 1014 dbSNP
rs1233032970 1023 dbSNP
rs143935653 1035 dbSNP
rs1187204461 1037 dbSNP
rs1413630900 1041 dbSNP
rs763269934 1043 dbSNP
rs1365954055 1047 dbSNP
rs1167538198 1059 dbSNP
rs1419096992 1062 dbSNP
rs142461240 1072 dbSNP
rs1001637430 1077 dbSNP
rs1319428442 1080 dbSNP
rs905822845 1085 dbSNP
rs1343095875 1087 dbSNP
rs1045740636 1090 dbSNP
rs1326334539 1093 dbSNP
rs1296497917 1094 dbSNP
rs1378341312 1095 dbSNP
rs1039280692 1096 dbSNP
rs949965108 1113 dbSNP
rs1335279504 1124 dbSNP
rs913192655 1127 dbSNP
rs1052866773 1128 dbSNP
rs1376087962 1129 dbSNP
rs1173274129 1131 dbSNP
rs1282359090 1143 dbSNP
rs1448966794 1156 dbSNP
rs1412946671 1162 dbSNP
rs909217374 1163 dbSNP
rs1237037331 1170 dbSNP
rs1484966039 1173 dbSNP
rs1190753914 1181 dbSNP
rs192903093 1188 dbSNP
rs1157204159 1191 dbSNP
rs1475736246 1197 dbSNP
rs925822594 1198 dbSNP
rs984793756 1207 dbSNP
rs1159177684 1210 dbSNP
rs1374370992 1211 dbSNP
rs1191327371 1215 dbSNP
rs1486372488 1216 dbSNP
rs916492368 1217 dbSNP
rs1209746776 1219 dbSNP
rs1396318333 1222 dbSNP
rs973314147 1223 dbSNP
rs1314602622 1224 dbSNP
rs1275611917 1228 dbSNP
rs1215509348 1237 dbSNP
rs1339068382 1238 dbSNP
rs1276871474 1241 dbSNP
rs1417111916 1242 dbSNP
rs1356032131 1243 dbSNP
rs10645914 1244 dbSNP
rs1277557859 1244 dbSNP
rs1277966687 1244 dbSNP
rs1345770741 1244 dbSNP
rs1353104193 1244 dbSNP
rs1408927241 1244 dbSNP
rs1456013548 1244 dbSNP
rs1480162726 1244 dbSNP
rs397707518 1244 dbSNP
rs775536440 1244 dbSNP
rs963391186 1245 dbSNP
rs1337355046 1251 dbSNP
rs1442705275 1252 dbSNP
rs1312322821 1253 dbSNP
rs539790252 1254 dbSNP
rs1274440104 1274 dbSNP
rs566054202 1282 dbSNP
rs974875214 1285 dbSNP
rs1236502131 1301 dbSNP
rs1281214445 1309 dbSNP
rs765221010 1312 dbSNP
rs554240337 1316 dbSNP
rs759139444 1337 dbSNP
rs1230966619 1344 dbSNP
rs1194636572 1346 dbSNP
rs1172357422 1348 dbSNP
rs1438711003 1362 dbSNP
rs1221323870 1364 dbSNP
rs1410323591 1364 dbSNP
rs929313632 1373 dbSNP
rs919364386 1381 dbSNP
rs964495390 1385 dbSNP
rs535929010 1393 dbSNP
rs911513605 1397 dbSNP
rs775973410 1407 dbSNP
rs28736479 1412 dbSNP
rs1475026923 1414 dbSNP
rs955604519 1416 dbSNP
rs766123372 1422 dbSNP
rs970984537 1428 dbSNP
rs1024784328 1433 dbSNP
rs1324977302 1439 dbSNP
rs1025924420 1448 dbSNP
rs760232274 1452 dbSNP
rs1032258414 1455 dbSNP
rs1000974541 1468 dbSNP
rs994323017 1473 dbSNP
rs11553468 1474 dbSNP
rs769038614 1476 dbSNP
rs1271736304 1482 dbSNP
rs1234261626 1490 dbSNP
rs997252959 1496 dbSNP
rs1215222763 1500 dbSNP
rs1253276916 1515 dbSNP
rs1445872363 1516 dbSNP
rs1001993288 1523 dbSNP
rs1437636219 1526 dbSNP
rs1190421324 1534 dbSNP
rs902034993 1536 dbSNP
rs550309868 1541 dbSNP
rs1039146646 1550 dbSNP
rs531496131 1551 dbSNP
rs1163932357 1564 dbSNP
rs1256518592 1566 dbSNP
rs1235722107 1569 dbSNP
rs1336083054 1574 dbSNP
rs62252145 1576 dbSNP
rs75587672 1578 dbSNP
rs1226681028 1588 dbSNP
rs888061660 1589 dbSNP
rs1320369958 1590 dbSNP
rs1327522659 1590 dbSNP
rs397876115 1590 dbSNP
rs1375534611 1592 dbSNP
rs1298971837 1593 dbSNP
rs1441682254 1595 dbSNP
rs1291793900 1596 dbSNP
rs1399308788 1597 dbSNP
rs1329004083 1598 dbSNP
rs1462992430 1600 dbSNP
rs1049287482 1602 dbSNP
rs866899455 1604 dbSNP
rs929319378 1611 dbSNP
rs1163538824 1613 dbSNP
rs1202850882 1620 dbSNP
rs1046145191 1631 dbSNP
rs1014234841 1633 dbSNP
rs137861773 1639 dbSNP
rs981944998 1646 dbSNP
rs1187188204 1647 dbSNP
rs1255357385 1665 dbSNP
rs1476036642 1666 dbSNP
rs1052939754 1674 dbSNP
rs4796 1675 dbSNP
rs1451978207 1695 dbSNP
rs1160356040 1697 dbSNP
rs80108312 1697 dbSNP
rs1414282226 1706 dbSNP
rs112999055 1709 dbSNP
rs746023170 1714 dbSNP
rs187532907 1723 dbSNP
rs1469356275 1726 dbSNP
rs1315951272 1727 dbSNP
rs943103533 1728 dbSNP
rs911684207 1737 dbSNP
rs987115012 1741 dbSNP
rs1273107519 1745 dbSNP
rs1353750061 1749 dbSNP
rs1209556637 1762 dbSNP
rs959185194 1770 dbSNP
rs1032290699 1774 dbSNP
rs1486613731 1793 dbSNP
rs1188381151 1801 dbSNP
rs928983322 1804 dbSNP
rs1249622858 1811 dbSNP
rs529663177 1820 dbSNP
rs1417529465 1823 dbSNP
rs1184297267 1848 dbSNP
rs1364624633 1848 dbSNP
rs1434125351 1850 dbSNP
rs918937186 1859 dbSNP
rs1171858000 1863 dbSNP
rs1377800094 1867 dbSNP
rs146195492 1869 dbSNP
rs1297942828 1875 dbSNP
rs963003921 1878 dbSNP
rs9837506 1882 dbSNP
rs1377201300 1883 dbSNP
rs1374927092 1887 dbSNP
rs770982172 1888 dbSNP
rs1020591883 1890 dbSNP
rs576575103 1893 dbSNP
rs1024374053 1898 dbSNP
rs1210785608 1899 dbSNP
rs182531172 1900 dbSNP
rs145885055 1903 dbSNP
rs1292889674 1904 dbSNP
rs1454054012 1906 dbSNP
rs191836975 1912 dbSNP
rs1007709119 1916 dbSNP
rs114148543 1918 dbSNP
rs1049795843 1919 dbSNP
rs778104258 1927 dbSNP
rs1463796733 1930 dbSNP
rs554524490 1931 dbSNP
rs186682113 1934 dbSNP
rs1299101627 1935 dbSNP
rs1439782385 1936 dbSNP
rs370791815 1936 dbSNP
rs540402602 1936 dbSNP
rs993734623 1938 dbSNP
rs1372589090 1947 dbSNP
rs891774390 1951 dbSNP
rs1294699299 1953 dbSNP
rs1454995360 1965 dbSNP
rs373028889 1966 dbSNP
rs1305700516 1968 dbSNP
rs1229335184 1972 dbSNP
rs1258531013 1973 dbSNP
rs535811226 1980 dbSNP
rs116614481 1987 dbSNP
rs1487120649 1988 dbSNP
rs1055876586 1991 dbSNP
rs115725305 1993 dbSNP
rs1186015123 1998 dbSNP
rs1039276320 2006 dbSNP
rs1417905553 2009 dbSNP
rs943238894 2019 dbSNP
rs1430872459 2022 dbSNP
rs141850263 2023 dbSNP
rs1417657935 2026 dbSNP
rs1460563961 2035 dbSNP
rs1351866015 2038 dbSNP
rs1396242428 2045 dbSNP
rs1436493253 2050 dbSNP
rs1287851924 2055 dbSNP
rs1359766884 2056 dbSNP
rs1051481249 2058 dbSNP
rs1383906474 2058 dbSNP
rs979772345 2069 dbSNP
rs929056968 2071 dbSNP
rs918884741 2073 dbSNP
rs1371500772 2077 dbSNP
rs1275217175 2080 dbSNP
rs1300294449 2084 dbSNP
rs1385055867 2085 dbSNP
rs535443216 2092 dbSNP
rs941607938 2100 dbSNP
rs910162266 2111 dbSNP
rs980666172 2119 dbSNP
rs965668197 2131 dbSNP
rs1017329597 2134 dbSNP
rs1474401693 2136 dbSNP
rs115233252 2137 dbSNP
rs1415504699 2141 dbSNP
rs759343079 2144 dbSNP
rs1024447611 2145 dbSNP
rs992834675 2148 dbSNP
rs773944916 2152 dbSNP
rs1298684750 2163 dbSNP
rs1046397107 2165 dbSNP
rs1354760292 2165 dbSNP
rs17029597 2165 dbSNP
rs1014293559 2166 dbSNP
rs894462301 2167 dbSNP
rs566402382 2174 dbSNP
rs1174373631 2178 dbSNP
rs1055907763 2179 dbSNP
rs1031624496 2180 dbSNP
rs1217463989 2180 dbSNP
rs1430869957 2182 dbSNP
rs936042958 2185 dbSNP
rs1190498547 2198 dbSNP
rs1263042112 2200 dbSNP
rs1193491925 2202 dbSNP
rs1176232265 2218 dbSNP
rs75196084 2219 dbSNP
rs77408272 2222 dbSNP
rs925117675 2223 dbSNP
rs1487361926 2233 dbSNP
rs1000239822 2239 dbSNP
rs1259656974 2244 dbSNP
rs904419548 2251 dbSNP
rs548095383 2252 dbSNP
rs1017549115 2257 dbSNP
rs376399639 2269 dbSNP
rs1432846216 2281 dbSNP
rs1255250165 2287 dbSNP
rs1007900751 2296 dbSNP
rs1359566760 2300 dbSNP
rs182488700 2300 dbSNP
rs945203754 2309 dbSNP
rs1277952512 2313 dbSNP
rs890268521 2315 dbSNP
rs976384827 2316 dbSNP
rs965700949 2319 dbSNP
rs1051597243 2322 dbSNP
rs562190925 2325 dbSNP
rs1279995272 2330 dbSNP
rs550639886 2331 dbSNP
rs1037354523 2335 dbSNP
rs532141399 2336 dbSNP
rs1441232754 2338 dbSNP
rs1178697339 2349 dbSNP
rs1394002300 2350 dbSNP
rs1399274629 2366 dbSNP
rs1452463197 2375 dbSNP
rs1337820425 2380 dbSNP
rs564679317 2391 dbSNP
rs746642635 2391 dbSNP
rs538049953 2393 dbSNP
rs1402713945 2395 dbSNP
rs926296523 2396 dbSNP
rs1447859041 2401 dbSNP
rs1325267337 2415 dbSNP
rs546884424 2415 dbSNP
rs1044629160 2419 dbSNP
rs546050023 2427 dbSNP
rs1213171360 2452 dbSNP
rs1339316017 2452 dbSNP
rs1275619999 2453 dbSNP
rs1458796102 2454 dbSNP
rs1198924863 2457 dbSNP
rs533387693 2457 dbSNP
rs1252023790 2460 dbSNP
rs1466711973 2461 dbSNP
rs572691852 2465 dbSNP
rs1401037567 2471 dbSNP
rs1475077393 2471 dbSNP
rs560723498 2474 dbSNP
rs1301527290 2493 dbSNP
rs956121065 2496 dbSNP
rs371459360 2497 dbSNP
rs1373937808 2499 dbSNP
rs1014491613 2504 dbSNP
rs924720975 2512 dbSNP
rs979156625 2523 dbSNP
rs1420173787 2535 dbSNP
rs968717546 2536 dbSNP
rs1018039393 2541 dbSNP
rs748489373 2548 dbSNP
rs1000286400 2551 dbSNP
rs1188728953 2562 dbSNP
rs753446660 2567 dbSNP
rs1233080449 2574 dbSNP
rs1254338162 2578 dbSNP
rs1197711379 2582 dbSNP
rs1332223632 2582 dbSNP
rs1042178748 2585 dbSNP
rs71068056 2589 dbSNP
rs77488490 2589 dbSNP
rs1030170698 2590 dbSNP
rs1190888468 2590 dbSNP
rs1446324509 2590 dbSNP
rs375530388 2590 dbSNP
rs386396304 2590 dbSNP
rs397751236 2590 dbSNP
rs1341694309 2591 dbSNP
rs144976427 2591 dbSNP
rs892269382 2591 dbSNP
rs1040280032 2592 dbSNP
rs1217983004 2594 dbSNP
rs1315966390 2596 dbSNP
rs1294660185 2597 dbSNP
rs1202873379 2598 dbSNP
rs1244881615 2598 dbSNP
rs1488616450 2599 dbSNP
rs755535235 2599 dbSNP
rs944590559 2599 dbSNP
rs542546075 2611 dbSNP
rs993357019 2612 dbSNP
rs1186946729 2617 dbSNP
rs1255196056 2622 dbSNP
rs1339306619 2623 dbSNP
rs910220407 2639 dbSNP
rs1310157192 2645 dbSNP
rs985798772 2646 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000205636.3 | 3UTR | UCAAGUAAAAAAAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000205636.3 | 3UTR | UCAAGUAAAAAAAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
115 hsa-miR-2681-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT058831 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT076301 ULK2 unc-51 like autophagy activating kinase 2 2 2
MIRT095503 PURA purine rich element binding protein A 2 12
MIRT097763 ARSK arylsulfatase family member K 2 2
MIRT170870 TAX1BP1 Tax1 binding protein 1 2 2
MIRT179045 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT189057 CLEC2D C-type lectin domain family 2 member D 2 8
MIRT241949 BTG1 BTG anti-proliferation factor 1 2 4
MIRT261860 ZRANB1 zinc finger RANBP2-type containing 1 2 2
MIRT309357 OTUD4 OTU deubiquitinase 4 2 2
MIRT340568 SMIM12 small integral membrane protein 12 2 4
MIRT351983 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT351986 MOB4 MOB family member 4, phocein 2 8
MIRT353140 RAB10 RAB10, member RAS oncogene family 2 2
MIRT387104 VEZF1 vascular endothelial zinc finger 1 2 2
MIRT441833 SLC30A7 solute carrier family 30 member 7 2 2
MIRT443778 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 4
MIRT448135 CMTM6 CKLF like MARVEL transmembrane domain containing 6 2 2
MIRT450638 ZMYM2 zinc finger MYM-type containing 2 2 2
MIRT494763 AP1G1 adaptor related protein complex 1 gamma 1 subunit 2 2
MIRT498299 DCAF8 DDB1 and CUL4 associated factor 8 2 2
MIRT505104 YTHDC1 YTH domain containing 1 2 6
MIRT507179 G3BP2 G3BP stress granule assembly factor 2 2 6
MIRT516638 ZNF318 zinc finger protein 318 2 4
MIRT520011 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT526877 GJD3 gap junction protein delta 3 2 2
MIRT529374 SKP1 S-phase kinase associated protein 1 2 2
MIRT530090 SHISA2 shisa family member 2 2 2
MIRT536514 KCTD10 potassium channel tetramerization domain containing 10 2 2
MIRT536559 JMJD1C jumonji domain containing 1C 2 2
MIRT536624 IPO7 importin 7 2 2
MIRT544378 ZNF266 zinc finger protein 266 2 2
MIRT547590 LIN28B lin-28 homolog B 2 2
MIRT548736 CREBBP CREB binding protein 2 2
MIRT551485 TMEM192 transmembrane protein 192 2 4
MIRT552322 ZNF791 zinc finger protein 791 2 4
MIRT553193 UBE2A ubiquitin conjugating enzyme E2 A 2 2
MIRT553719 TBX18 T-box 18 2 2
MIRT554573 RRAS2 RAS related 2 2 2
MIRT557038 HOXB3 homeobox B3 2 2
MIRT559566 ARF1 ADP ribosylation factor 1 2 2
MIRT560134 INO80D INO80 complex subunit D 2 2
MIRT560406 JUN Jun proto-oncogene, AP-1 transcription factor subunit 2 2
MIRT561712 PTMA prothymosin, alpha 2 2
MIRT562688 ABI2 abl interactor 2 2 2
MIRT563214 FXN frataxin 2 2
MIRT566288 PROX1 prospero homeobox 1 2 4
MIRT567369 GTPBP3 GTP binding protein 3, mitochondrial 2 2
MIRT571380 JKAMP JNK1/MAPK8-associated membrane protein 2 2
MIRT574743 GOLGA4 golgin A4 2 2
MIRT576816 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT609984 ZHX1 zinc fingers and homeoboxes 1 2 4
MIRT610518 HIAT1 major facilitator superfamily domain containing 14A 2 2
MIRT612203 NKTR natural killer cell triggering receptor 2 4
MIRT612224 DHX33 DEAH-box helicase 33 2 6
MIRT612889 HOOK3 hook microtubule tethering protein 3 2 2
MIRT613639 DUSP18 dual specificity phosphatase 18 2 4
MIRT614161 PHF8 PHD finger protein 8 2 2
MIRT614630 WDR13 WD repeat domain 13 2 4
MIRT615001 FXR1 FMR1 autosomal homolog 1 2 4
MIRT615665 TSC22D2 TSC22 domain family member 2 2 2
MIRT615976 KAT6A lysine acetyltransferase 6A 2 2
MIRT616328 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT616495 AIPL1 aryl hydrocarbon receptor interacting protein like 1 2 2
MIRT616585 ZNF460 zinc finger protein 460 2 2
MIRT616870 ARPC1B actin related protein 2/3 complex subunit 1B 2 4
MIRT617631 RXRA retinoid X receptor alpha 2 2
MIRT620339 TLN1 talin 1 2 2
MIRT621658 UBE4B ubiquitination factor E4B 2 2
MIRT621824 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT622134 SOX4 SRY-box 4 2 2
MIRT622154 SNTG1 syntrophin gamma 1 2 2
MIRT622298 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT622531 RAB9B RAB9B, member RAS oncogene family 2 2
MIRT622596 PRRC2B proline rich coiled-coil 2B 2 2
MIRT623328 MAK16 MAK16 homolog 2 2
MIRT624499 C8orf44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT624720 AP1S2 adaptor related protein complex 1 sigma 2 subunit 2 2
MIRT625990 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT626143 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT626499 ARHGAP9 Rho GTPase activating protein 9 2 2
MIRT627023 CREBL2 cAMP responsive element binding protein like 2 2 2
MIRT635710 HFM1 HFM1, ATP dependent DNA helicase homolog 2 2
MIRT635725 CCDC58 coiled-coil domain containing 58 2 2
MIRT637121 MKX mohawk homeobox 2 2
MIRT639969 POU5F1B POU class 5 homeobox 1B 2 2
MIRT640962 GPRASP1 G protein-coupled receptor associated sorting protein 1 2 4
MIRT641067 HHIPL1 HHIP like 1 2 2
MIRT644800 NKX3-2 NK3 homeobox 2 2 2
MIRT644958 STEAP4 STEAP4 metalloreductase 2 2
MIRT649152 LRTM1 leucine rich repeats and transmembrane domains 1 2 2
MIRT651887 UFD1L ubiquitin recognition factor in ER associated degradation 1 2 2
MIRT652165 TRIM66 tripartite motif containing 66 2 2
MIRT652565 TLR6 toll like receptor 6 2 2
MIRT653127 SRPX2 sushi repeat containing protein, X-linked 2 2 2
MIRT655622 ONECUT1 one cut homeobox 1 2 2
MIRT656245 MEX3A mex-3 RNA binding family member A 2 2
MIRT656837 KLF7 Kruppel like factor 7 2 2
MIRT656990 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT660337 BCL10 B-cell CLL/lymphoma 10 2 2
MIRT660393 B3GALT5 beta-1,3-galactosyltransferase 5 2 2
MIRT660940 ACER3 alkaline ceramidase 3 2 2
MIRT661509 C8orf82 chromosome 8 open reading frame 82 2 2
MIRT665000 KLF2 Kruppel like factor 2 2 2
MIRT665106 TNFSF8 TNF superfamily member 8 2 2
MIRT665547 UCHL5 ubiquitin C-terminal hydrolase L5 2 2
MIRT687376 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT711828 SIGLEC9 sialic acid binding Ig like lectin 9 2 2
MIRT713313 VLDLR very low density lipoprotein receptor 2 2
MIRT715654 PPM1K protein phosphatase, Mg2+/Mn2+ dependent 1K 2 2
MIRT715735 CD226 CD226 molecule 2 2
MIRT717255 SLC44A1 solute carrier family 44 member 1 2 2
MIRT717950 MIA3 MIA family member 3, ER export factor 2 2
MIRT719709 CD101 CD101 molecule 2 2
MIRT723893 NUDT21 nudix hydrolase 21 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-2681-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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