miRTarBase - #MIRT448485


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pre-miRNA Information
pre-miRNA hsa-mir-216b   
Genomic Coordinates chr2: 56000714 - 56000795
Description Homo sapiens miR-216b stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-216b-3p
Sequence 49| ACACACUUACCCGUAGAGAUUCUA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 9 2 - 56000739 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1032185572 4 dbSNP
rs1291886633 6 dbSNP
rs1195180466 10 dbSNP
rs761473579 10 dbSNP
rs751204276 12 dbSNP
rs368125248 13 dbSNP
rs755646560 13 dbSNP
rs1307586870 14 dbSNP
rs907200088 16 dbSNP
rs763696104 22 dbSNP
rs762699560 24 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B5PHM2 miR-216b Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Plasma MiRNA qPCR analyses
Gene Information
Gene Symbol SEMA4F   
Synonyms M-SEMA, PRO2353, S4F, SEMAM, SEMAW, m-Sema-M
Description ssemaphorin 4F
Transcript NM_004263   
Expression
Putative miRNA Targets on SEMA4F
3'UTR of SEMA4F
(miRNA target sites are highlighted)		 
>SEMA4F|NM_004263|3'UTR
   1 AGCTGGGCAAATGACCACTAGTGTATAAGTGATCACTGGAACGGAGTGACCACTGAGATGCTGGGGGTCACTGGGCCTGG
  81 AAGACCATCCCAGCCTCTGAGTTCTCTTTGAGTATGAGTGATTACTTGGATTTTAGTATCTGTTCTCTCTGAGCCTGGAT
 161 GGGCTTGGGGCCAGACCTTTGCCTGATTCCTGATTCCCATGAGAAATCAGAACTGCTTTCTGCAGCAAATCAGGGCTTCC
 241 CCCTAACATCTGAACTCCTGTAAACCTTCATCCCTGGCCCCCTATCTTGGGCCCATTAGTTTTGGGGATGGGGCACAGGG
 321 CATAGCTATGACTTTGCTTTCTGGTTGGAGCCTGGCCGGAAGGAAGAGCCCTGGAGGTGGTTGGGGGCAAATGTGCCCTG
 401 AGTCCTTGGGGTGGTTCTGCTTATTCTTCAAGTTTATCTGAATCTGTGGGGAGTGCATGATCCCCATGTTGCAATATGGA
 481 GTCTCTGCCCTGAGATCTTCCCCATCTCAGTTTTCCTTCCATGAAAGAGTACGTGTAAATACATAGTGTTCATAAGAGAC
 561 CTGGCCACATGTGCATGAATGACTGGGCCGATGCTTAGGAATATTTATGAGGGATGGGGAGGGAGACAATTGGAATGGGG
 641 GCGTTGCCTGCAGAACTTTAGACCCTGTAGCCATAGAGGGAATGGCGTTCCTTTCTAAAAGGAACTGAAACACTGCCCCT
 721 CTCCCCATTGCCCCACAACCTTACTCTAAATTTGAGTAGAGAAAAGCTCCTAAAGTGACCTTCCGGGTGGGAAGGGCAGC
 801 AGTACACATGACCCCATCCTTTTCTTTGTTTTTACCCCCTGGCTGCCACCACTGCCATGTCACAGCTGCTTTCTCTGGCT
 881 GGAGTGTAGGCTGTACCCCATTTCCTTGGCTCCCATTAAAAATCAACAACATTCTAATGATTAGGGAACAACAGAAGGGG
 961 AACAGTCATAGGATATACGAGCAGTATAAAGATACGTTTGCAATCAGTGACTACTCAGGGTGACACCCTTGCCCTAAAGC
1041 AGGAGTCCCCCCTACCTGGGGTCCATGGACTCCCTGAAATTGTATGCAAAATGTTGTTTGTACATGTGTGTCTGTATGTC
1121 TCTGTGGGGAGGTTTTATGGCTTTTGTCAGATTTTCAAGGCCTTAACAAAGTTAAAGGACCACTGCCCTGAGGTTACTGC
1201 ACTGAGGCCAAGTTAGGATGGCATCACTCTGTGGCAGCTCTCCCTGGACTTGCCCTGCCTGGAACAGGGTGATTTGCTGG
1281 AATGGAGTTACCACTGAGATGCCAAAGGTTGCTGGGTCTGGAAGACTGTTGTGGCCTCTCAGTTCTCTTTGAGTCTGACT
1361 GACTGTGGCCAGTCCCTGGACTGGTAGCTGCTGGAGGCCTTCTTGTTTCTCCAGTCCCTGGAAGCTGAGCTCTATGTGTA
1441 TTTGATGACATTGTCAGCTCTTACCAAACGTCAAGACCTCTTCCTGCTTGACCACTCGCACATGGCTCTAGGCTTCTCCT
1521 GCTGAGTCCTGGTCTTGGCCTGTGAATGTGCCTCGTTCATCCCTGGTGCTTGAGCCCCTCAAGCTCCAGTCAATGATCCA
1601 GTCCTTCCCCTTTGAAGTTTTCTGCTCTACTTTCCTTGGCAGCAGCCTGTGAACTACTCAAAAGAGTCCCCTTGGGTTTG
1681 GAATTATCAGTGGCTTTGCCACTAGTAAATGTGTGATCTTCGGCAAGTAACCTAACCTAGGGACATCAGTTTACTCATCT
1761 GCGAAGTGGGGATAATAAAACCTACCTCAGGGTTGCTTCAAGGATTAAATGAGAAAATATGTCAACAATAAAGACCTGTC
1841 TGTACCAATAGATGTTGTTATTGCAAAAATGGGCTTACTATCCATAACCATATAGCTTAACTATATGATAACCATGACAT
1921 TCGTAGGCTGGGCATGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACAAGGTCAGGAG
2001 ATCGAGACCATTCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGGG
2081 CCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGTGGAGTTTGCAGTGAGCCAAGAT
2161 CACGCCACTGCACTCCAGCCTGGGCAACAGAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAGATAACCATGACACTCGC
2241 AATCATATTAAGCCTCACTCAGTAAAGGACAGTCATTGTTTCACAGATATCCTGTTCTGGGTCACCTCTGGACAGCTCAT
2321 AGCTGCTGGTTTCTAGGTTTTAGGAGGCAGATCTATGATTTTTGTAATCCTCAGACCTGTCTGACCTTAGTGGCCTGAGA
2401 TCCCTTTGTATAGAATGGAGGAAGGCTGTGTGTTCTTTGGTTTACCCTCAGCCTATCTTTCAACCCCACTCACTTGAGGT
2481 TGTGGCCTAGTTCCTCTTTGGGGGAGGGAGGAAGGTGGGGAGATGTCAAAGGGGACTGGGCTTCCTGTGGGGAGTGGGAG
2561 AGAAGAGTTTTTCAAGGAGGAGAGAGACCAGGGCTCTTATACTCTGGGCCACTATCTGCCTGCTCTAATCACCTAGGGCC
2641 AGGCACCAGACAACTAGGGATGGCCTCTTTACCCCAAAGCCTGCTGAAATTACTCAAACTAGCCAATCCTAAGTCTGCCT
2721 ACCCTGCCTCAGTCATTCCTTCCAATGGAAACCACAATAAGCACTCTTGCCCACGTTTTCCCTGCTCCCTCTGCATCCCA
2801 ACTGACCCTGGTGCTTCCCCATGTGGCCCCTGTATAGTGTGCTTTGCCTCCTGTTTCTAGGGACCTGTGAGTATCAGCTT
2881 TCTCGATGACAGTCATTTCTGTGTCTATGTGTCTTATTATACCTTATTAAAACAAACCTGGGTACATTTGTAAGACAGCA
2961 GGGATTCTCTGAAGATTAATGATTGAGAAGGATGATTGGACCTGTCTAGTCAGGGAGGCTGAGGCCTCAGGCCTTCATTA
3041 GGCACGTTGCATGTCTGTCAAGTAAGGGCCACTAATCACCTCACATGGGTTCATCTGAACTTTATGCCAGCCCAAAACAC
3121 GAGGACGTGCCACCCATCCTCAGCACTCTCAAGACACACTTAAGTGTGTTTGATACGTAAGCTCCAATTCCTTCCTCCAT
3201 AAGAAGAGAGAAGGCAGAAGTGGCTTTCCCCGAGGTGAGGACGGGGATGGGAGTTTTTTCTTTTGAGTGATGTAGACCTA
3281 TGCCCTGCTTCCATGCCACTTCCTCAGATGTGACAGACCTCTGCTGGGATGGAATGTGTGTTTGCTGGAGACAGCTGTGG
3361 CATAGAGGATTGTGAGAAAGGGTCCCCATGCTTGGTGTGGAAGGAGGGAGCTGCTCACCCTCTGTATGGGCTTGGATGAG
3441 GAGCTTCTCAGCGGCAGTCATAAGAACCAGAGGATTTTCTGCCCTTTGCTGGGAGCCACATGAGCCCCCTGGATTCATGT
3521 GGAATTCTTGGGAGAGGGATGACCACCCTGAAGATGGCTGAGATCAAATATCTCATCAGATGACTGGATGCTTAGAATCG
3601 GGTTAACTTGATTAAATAAATAAATAGAAATAGTTTTTGTACCTAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aucUUAGAG----AUGCCCAUUCACACa 5'
             | ||||     ||   |||||||| 
Target 5' agcACTCTCAAGACACACTTAAGTGTGt 3'
 3142 - 3169 151.00 -12.20
2 
miRNA  3' aucUUAGAGAUG-CCC-A--UU-CACACa 5'
             :| ||||:| ||| |  || ||||| 
Target 5' acaGACCTCTGCTGGGATGGAATGTGTGt 3'
 3313 - 3341 131.00 -19.00
3 
miRNA  3' auCUUAGA-GAUGCCCAUUCACACa 5'
            |: |:| | ||  |||| |||| 
Target 5' gtGGCTTTGCCACTAGTAAATGTGt 3'
 1690 - 1714 130.00 -11.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM3963087 1 COSMIC
COSN31539250 4 COSMIC
COSN19372812 5 COSMIC
COSN20860286 9 COSMIC
COSN30447398 17 COSMIC
COSN30152359 18 COSMIC
COSN30460582 35 COSMIC
COSN30133148 43 COSMIC
COSN30520302 63 COSMIC
COSN30528860 68 COSMIC
COSN31599304 105 COSMIC
COSN30460576 107 COSMIC
COSN30538665 734 COSMIC
COSN5956382 992 COSMIC
COSN31523869 1072 COSMIC
COSN28667645 1074 COSMIC
COSN8609587 1074 COSMIC
COSN8609588 1102 COSMIC
COSN26638661 1128 COSMIC
COSN26538036 1186 COSMIC
COSN16487538 1198 COSMIC
COSN30174483 1218 COSMIC
COSN31596055 1463 COSMIC
COSN31491108 1517 COSMIC
COSN31550462 1517 COSMIC
COSN31530530 1653 COSMIC
COSN30172581 1689 COSMIC
COSN18943958 1690 COSMIC
COSN30543625 1792 COSMIC
COSN30544937 1822 COSMIC
COSN15688623 1874 COSMIC
COSN17260059 1976 COSMIC
COSN24956646 2460 COSMIC
COSN9386710 2530 COSMIC
COSN22752863 2597 COSMIC
COSN16728308 2775 COSMIC
COSN16684609 3583 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1445925367 8 dbSNP
rs1302388941 9 dbSNP
rs769281881 12 dbSNP
rs774996804 13 dbSNP
rs1423496968 19 dbSNP
rs1192014228 22 dbSNP
rs1276673344 22 dbSNP
rs1317714984 24 dbSNP
rs370593814 26 dbSNP
rs1219743517 27 dbSNP
rs188736879 30 dbSNP
rs774150325 33 dbSNP
rs761494907 43 dbSNP
rs530434362 44 dbSNP
rs1482690084 62 dbSNP
rs1235261921 67 dbSNP
rs1199934481 68 dbSNP
rs941764168 77 dbSNP
rs1257334946 92 dbSNP
rs1216644847 93 dbSNP
rs181173322 95 dbSNP
rs1170817645 107 dbSNP
rs1395696656 109 dbSNP
rs919108870 111 dbSNP
rs929106491 112 dbSNP
rs1057050532 113 dbSNP
rs1333492749 119 dbSNP
rs910296580 137 dbSNP
rs1403707390 140 dbSNP
rs1447579337 141 dbSNP
rs895700421 146 dbSNP
rs942888093 153 dbSNP
rs948733405 158 dbSNP
rs1169158900 160 dbSNP
rs1306955399 166 dbSNP
rs1459835152 174 dbSNP
rs1348274970 196 dbSNP
rs1412010832 207 dbSNP
rs1164454321 209 dbSNP
rs1044413566 244 dbSNP
rs904631312 250 dbSNP
rs1000274053 255 dbSNP
rs183751621 261 dbSNP
rs530499012 265 dbSNP
rs1457820843 278 dbSNP
rs904136097 279 dbSNP
rs1231700171 281 dbSNP
rs1032144832 282 dbSNP
rs1489395837 292 dbSNP
rs1265844839 293 dbSNP
rs1243757734 300 dbSNP
rs372453768 303 dbSNP
rs766371581 306 dbSNP
rs1052464774 325 dbSNP
rs1311721866 327 dbSNP
rs1241045155 331 dbSNP
rs896439639 335 dbSNP
rs141648593 346 dbSNP
rs1204568644 349 dbSNP
rs1024173922 351 dbSNP
rs376533893 358 dbSNP
rs188079194 359 dbSNP
rs1456705006 364 dbSNP
rs1006032625 367 dbSNP
rs1029880362 369 dbSNP
rs954289694 374 dbSNP
rs180768871 382 dbSNP
rs1017208345 383 dbSNP
rs867690653 387 dbSNP
rs1434879434 392 dbSNP
rs1267947597 393 dbSNP
rs1189305649 395 dbSNP
rs1489797272 412 dbSNP
rs1287808776 414 dbSNP
rs1217635615 417 dbSNP
rs144862383 418 dbSNP
rs1196587279 432 dbSNP
rs922963393 433 dbSNP
rs547467051 437 dbSNP
rs764255536 438 dbSNP
rs954489547 439 dbSNP
rs1235470676 441 dbSNP
rs1332240718 447 dbSNP
rs560679618 451 dbSNP
rs1301186999 454 dbSNP
rs973194160 457 dbSNP
rs918961441 458 dbSNP
rs1362863012 462 dbSNP
rs1299134009 466 dbSNP
rs1419964459 467 dbSNP
rs1359469509 468 dbSNP
rs985814315 469 dbSNP
rs1478716667 482 dbSNP
rs929162775 485 dbSNP
rs1167441584 498 dbSNP
rs746662466 499 dbSNP
rs1431219742 510 dbSNP
rs1265086465 523 dbSNP
rs757223814 533 dbSNP
rs535756675 534 dbSNP
rs1385463687 544 dbSNP
rs1345816164 552 dbSNP
rs948601085 553 dbSNP
rs1303961795 559 dbSNP
rs1255433879 562 dbSNP
rs1222250473 563 dbSNP
rs1342893490 565 dbSNP
rs1372395907 570 dbSNP
rs554646784 577 dbSNP
rs1315779750 588 dbSNP
rs925419186 590 dbSNP
rs904538053 591 dbSNP
rs576541854 592 dbSNP
rs1053081964 600 dbSNP
rs1425644080 601 dbSNP
rs896727564 608 dbSNP
rs1053213481 610 dbSNP
rs1280873788 628 dbSNP
rs3771749 629 dbSNP
rs998401972 630 dbSNP
rs1029785183 631 dbSNP
rs750531034 632 dbSNP
rs1255597792 635 dbSNP
rs1201821035 639 dbSNP
rs114072259 643 dbSNP
rs756608701 644 dbSNP
rs963076994 652 dbSNP
rs1218480538 654 dbSNP
rs1337857736 667 dbSNP
rs780755385 675 dbSNP
rs1026096852 677 dbSNP
rs1449803611 683 dbSNP
rs1340658010 685 dbSNP
rs574156567 687 dbSNP
rs992683309 688 dbSNP
rs1402443733 705 dbSNP
rs917074610 715 dbSNP
rs1331964625 719 dbSNP
rs1464986197 720 dbSNP
rs1417161100 722 dbSNP
rs1006232044 727 dbSNP
rs969850864 728 dbSNP
rs749620551 735 dbSNP
rs1456670990 739 dbSNP
rs1016068042 740 dbSNP
rs577420961 741 dbSNP
rs1459141568 749 dbSNP
rs1242470463 755 dbSNP
rs1238797351 759 dbSNP
rs1198584281 760 dbSNP
rs925825213 767 dbSNP
rs1436528188 773 dbSNP
rs1292507251 776 dbSNP
rs1229212875 780 dbSNP
rs187270479 785 dbSNP
rs993433405 786 dbSNP
rs1030706027 789 dbSNP
rs1378491579 800 dbSNP
rs748074258 801 dbSNP
rs532139513 810 dbSNP
rs1435009822 811 dbSNP
rs1053523680 813 dbSNP
rs1319205501 822 dbSNP
rs1352661082 835 dbSNP
rs1325336992 840 dbSNP
rs1405727810 845 dbSNP
rs954633923 849 dbSNP
rs913357539 858 dbSNP
rs934054223 859 dbSNP
rs559914483 867 dbSNP
rs1441712510 869 dbSNP
rs1381025853 876 dbSNP
rs1178054989 896 dbSNP
rs530303004 901 dbSNP
rs1312231764 912 dbSNP
rs1248938092 913 dbSNP
rs1017254073 929 dbSNP
rs1451387347 932 dbSNP
rs1289977208 938 dbSNP
rs755423234 939 dbSNP
rs968475347 940 dbSNP
rs542537152 942 dbSNP
rs375441036 943 dbSNP
rs1309408112 957 dbSNP
rs1247318992 961 dbSNP
rs3025994 964 dbSNP
rs772970056 970 dbSNP
rs1276544746 980 dbSNP
rs1468800279 984 dbSNP
rs1208012625 996 dbSNP
rs1301010364 997 dbSNP
rs1421785843 998 dbSNP
rs1246126560 1004 dbSNP
rs889969263 1014 dbSNP
rs1006972566 1015 dbSNP
rs1158533475 1017 dbSNP
rs1486520730 1017 dbSNP
rs1186624462 1023 dbSNP
rs1038596341 1027 dbSNP
rs1192303067 1029 dbSNP
rs1254937503 1032 dbSNP
rs1421662244 1047 dbSNP
rs898733796 1048 dbSNP
rs138785077 1050 dbSNP
rs1489095260 1056 dbSNP
rs1166736731 1065 dbSNP
rs376659291 1082 dbSNP
rs1026381680 1094 dbSNP
rs551849833 1097 dbSNP
rs1314620265 1101 dbSNP
rs570165572 1104 dbSNP
rs988324343 1105 dbSNP
rs1361684798 1106 dbSNP
rs1281187685 1109 dbSNP
rs1401589309 1124 dbSNP
rs1157501381 1130 dbSNP
rs950525846 1138 dbSNP
rs1288502161 1141 dbSNP
rs1014026688 1154 dbSNP
rs1024038969 1157 dbSNP
rs1431511786 1160 dbSNP
rs1302312349 1167 dbSNP
rs1428810121 1168 dbSNP
rs1377117252 1171 dbSNP
rs1360992795 1172 dbSNP
rs969883272 1180 dbSNP
rs918186393 1182 dbSNP
rs1469778533 1188 dbSNP
rs949647476 1198 dbSNP
rs1173347858 1214 dbSNP
rs979900461 1220 dbSNP
rs1478351296 1221 dbSNP
rs578236094 1222 dbSNP
rs1294195777 1224 dbSNP
rs1484659792 1238 dbSNP
rs905178209 1239 dbSNP
rs373549828 1243 dbSNP
rs1210170117 1244 dbSNP
rs942120842 1245 dbSNP
rs925928229 1250 dbSNP
rs1261159077 1253 dbSNP
rs1220304567 1258 dbSNP
rs1318337915 1259 dbSNP
rs1294527750 1263 dbSNP
rs957515830 1283 dbSNP
rs1213065257 1292 dbSNP
rs367724522 1293 dbSNP
rs988854288 1302 dbSNP
rs1303552237 1309 dbSNP
rs1227555821 1312 dbSNP
rs1266119739 1315 dbSNP
rs1318636356 1329 dbSNP
rs1216462596 1330 dbSNP
rs1404624312 1339 dbSNP
rs1254903011 1341 dbSNP
rs771680670 1342 dbSNP
rs79648460 1347 dbSNP
rs1037713747 1348 dbSNP
rs192127286 1357 dbSNP
rs1415482121 1359 dbSNP
rs535371785 1359 dbSNP
rs1051126491 1360 dbSNP
rs1240651880 1362 dbSNP
rs1200465990 1363 dbSNP
rs1472447200 1364 dbSNP
rs1250592386 1365 dbSNP
rs993764521 1368 dbSNP
rs1323796871 1375 dbSNP
rs1180501593 1376 dbSNP
rs1313702456 1387 dbSNP
rs1410682038 1387 dbSNP
rs911270202 1391 dbSNP
rs942905296 1392 dbSNP
rs1038499934 1398 dbSNP
rs1296857942 1399 dbSNP
rs772774332 1399 dbSNP
rs1459756661 1400 dbSNP
rs557334651 1401 dbSNP
rs570062095 1402 dbSNP
rs994812983 1410 dbSNP
rs537395848 1417 dbSNP
rs867475442 1418 dbSNP
rs1047282883 1425 dbSNP
rs200758368 1426 dbSNP
rs1007454358 1430 dbSNP
rs746545779 1435 dbSNP
rs376683199 1452 dbSNP
rs1249720811 1464 dbSNP
rs363643 1466 dbSNP
rs112525938 1468 dbSNP
rs1292160221 1469 dbSNP
rs1222056579 1470 dbSNP
rs1031464903 1471 dbSNP
rs1357487605 1489 dbSNP
rs1436671652 1491 dbSNP
rs1335746520 1498 dbSNP
rs969790077 1499 dbSNP
rs1388961415 1501 dbSNP
rs200054097 1503 dbSNP
rs1302870722 1507 dbSNP
rs771732346 1512 dbSNP
rs1350131818 1515 dbSNP
rs1408936638 1524 dbSNP
rs1277528306 1526 dbSNP
rs553270993 1540 dbSNP
rs1159997631 1545 dbSNP
rs1375346645 1549 dbSNP
rs1453854263 1551 dbSNP
rs373786985 1555 dbSNP
rs181737279 1556 dbSNP
rs866231195 1559 dbSNP
rs1434788744 1566 dbSNP
rs375138259 1576 dbSNP
rs980948298 1577 dbSNP
rs363644 1582 dbSNP
rs563683047 1587 dbSNP
rs879648618 1592 dbSNP
rs1288409370 1594 dbSNP
rs531248446 1630 dbSNP
rs1205861050 1631 dbSNP
rs926631001 1632 dbSNP
rs1258975676 1634 dbSNP
rs942068895 1639 dbSNP
rs1020159965 1662 dbSNP
rs13411846 1663 dbSNP
rs752759358 1664 dbSNP
rs929380398 1665 dbSNP
rs770638240 1668 dbSNP
rs775204267 1689 dbSNP
rs1482511876 1691 dbSNP
rs1202635399 1694 dbSNP
rs115822895 1716 dbSNP
rs890256892 1717 dbSNP
rs186051392 1722 dbSNP
rs767669523 1723 dbSNP
rs920101891 1733 dbSNP
rs546702362 1738 dbSNP
rs930136867 1741 dbSNP
rs1047766644 1751 dbSNP
rs1370079994 1757 dbSNP
rs896707423 1759 dbSNP
rs879101226 1763 dbSNP
rs1428062325 1768 dbSNP
rs1194183760 1770 dbSNP
rs1446588062 1772 dbSNP
rs561724098 1780 dbSNP
rs1202228399 1787 dbSNP
rs1462201656 1792 dbSNP
rs949734613 1796 dbSNP
rs1045425120 1813 dbSNP
rs541002805 1821 dbSNP
rs1271091311 1829 dbSNP
rs1227752137 1835 dbSNP
rs1325458072 1838 dbSNP
rs1442669628 1847 dbSNP
rs1274136454 1849 dbSNP
rs1397253765 1850 dbSNP
rs1406818484 1852 dbSNP
rs550799027 1853 dbSNP
rs1368729168 1870 dbSNP
rs1001274270 1881 dbSNP
rs1336001539 1883 dbSNP
rs569135460 1888 dbSNP
rs1032736732 1891 dbSNP
rs56664282 1902 dbSNP
rs1425535107 1905 dbSNP
rs1010036120 1906 dbSNP
rs1031329038 1913 dbSNP
rs1020653665 1917 dbSNP
rs1475230750 1921 dbSNP
rs190377753 1923 dbSNP
rs1013980330 1924 dbSNP
rs370413462 1937 dbSNP
rs1242554963 1945 dbSNP
rs1025565318 1946 dbSNP
rs1340925292 1947 dbSNP
rs986786458 1958 dbSNP
rs1274692341 1969 dbSNP
rs570854864 1971 dbSNP
rs963985044 1986 dbSNP
rs534791426 1989 dbSNP
rs1382903462 1996 dbSNP
rs528938297 2004 dbSNP
rs926915397 2005 dbSNP
rs930144583 2016 dbSNP
rs574929014 2024 dbSNP
rs1329363829 2025 dbSNP
rs963586559 2030 dbSNP
rs973390709 2032 dbSNP
rs182593410 2035 dbSNP
rs1445418359 2036 dbSNP
rs1470201206 2037 dbSNP
rs918213734 2040 dbSNP
rs949599588 2043 dbSNP
rs1045455643 2064 dbSNP
rs1389621383 2065 dbSNP
rs905543885 2068 dbSNP
rs936981454 2069 dbSNP
rs1224277339 2076 dbSNP
rs1054619920 2077 dbSNP
rs892877560 2079 dbSNP
rs1410276025 2080 dbSNP
rs557142162 2094 dbSNP
rs1392074617 2097 dbSNP
rs1020097859 2098 dbSNP
rs1326562274 2100 dbSNP
rs575497572 2101 dbSNP
rs919242916 2106 dbSNP
rs1304691575 2108 dbSNP
rs1425583206 2111 dbSNP
rs1365168803 2112 dbSNP
rs546108901 2123 dbSNP
rs1224617109 2124 dbSNP
rs1161812061 2125 dbSNP
rs1421584514 2129 dbSNP
rs929385907 2130 dbSNP
rs563715646 2132 dbSNP
rs572837264 2133 dbSNP
rs964016513 2138 dbSNP
rs1248851022 2149 dbSNP
rs995487525 2153 dbSNP
rs1337483120 2158 dbSNP
rs1051823707 2161 dbSNP
rs374815205 2164 dbSNP
rs1247957615 2165 dbSNP
rs1463569271 2168 dbSNP
rs1223183010 2178 dbSNP
rs911957259 2180 dbSNP
rs547130574 2182 dbSNP
rs1285016874 2192 dbSNP
rs749973675 2202 dbSNP
rs943223085 2202 dbSNP
rs561777304 2203 dbSNP
rs1433082245 2205 dbSNP
rs1003118312 2207 dbSNP
rs1177673664 2207 dbSNP
rs1327323289 2207 dbSNP
rs1432052986 2207 dbSNP
rs370845200 2207 dbSNP
rs1427569420 2217 dbSNP
rs1196865790 2224 dbSNP
rs951495225 2231 dbSNP
rs983380196 2236 dbSNP
rs918079746 2239 dbSNP
rs1264919175 2240 dbSNP
rs1223969686 2243 dbSNP
rs528989246 2248 dbSNP
rs1281083200 2259 dbSNP
rs1216579769 2262 dbSNP
rs981020513 2275 dbSNP
rs926825910 2285 dbSNP
rs1415374824 2286 dbSNP
rs187062860 2288 dbSNP
rs1462830420 2289 dbSNP
rs1337979824 2291 dbSNP
rs1469695782 2300 dbSNP
rs937035149 2307 dbSNP
rs1404403518 2309 dbSNP
rs189897909 2315 dbSNP
rs1429987033 2319 dbSNP
rs1419775272 2338 dbSNP
rs1185501644 2340 dbSNP
rs113295580 2347 dbSNP
rs1244381160 2348 dbSNP
rs1460782717 2349 dbSNP
rs1379972855 2352 dbSNP
rs1261065185 2356 dbSNP
rs891421175 2365 dbSNP
rs1308359694 2366 dbSNP
rs1295120335 2367 dbSNP
rs565535653 2373 dbSNP
rs970207970 2376 dbSNP
rs1002357767 2384 dbSNP
rs1335363162 2398 dbSNP
rs551736679 2403 dbSNP
rs1300331803 2404 dbSNP
rs1462813211 2405 dbSNP
rs3025995 2427 dbSNP
rs6716578 2430 dbSNP
rs1169322771 2431 dbSNP
rs535062499 2435 dbSNP
rs1427363989 2436 dbSNP
rs868092368 2436 dbSNP
rs1007977186 2437 dbSNP
rs371148490 2448 dbSNP
rs1039605913 2456 dbSNP
rs1234323299 2459 dbSNP
rs754025815 2461 dbSNP
rs1480845001 2466 dbSNP
rs995953815 2469 dbSNP
rs1026970790 2472 dbSNP
rs1202733423 2476 dbSNP
rs973588480 2482 dbSNP
rs951577760 2487 dbSNP
rs919259895 2490 dbSNP
rs1292661690 2495 dbSNP
rs950782742 2499 dbSNP
rs987874524 2501 dbSNP
rs1276849394 2502 dbSNP
rs1004316184 2512 dbSNP
rs1349135564 2516 dbSNP
rs943420979 2517 dbSNP
rs1207453676 2521 dbSNP
rs1038898818 2523 dbSNP
rs1025022637 2526 dbSNP
rs970891516 2528 dbSNP
rs546679257 2542 dbSNP
rs1285042135 2549 dbSNP
rs1367026978 2557 dbSNP
rs980925746 2561 dbSNP
rs762384346 2562 dbSNP
rs1186004953 2584 dbSNP
rs1423447614 2585 dbSNP
rs1366133954 2591 dbSNP
rs925751601 2597 dbSNP
rs935904626 2597 dbSNP
rs568498615 2601 dbSNP
rs1179724402 2602 dbSNP
rs1490919839 2603 dbSNP
rs1269867198 2606 dbSNP
rs765882215 2611 dbSNP
rs891697802 2612 dbSNP
rs1476042066 2613 dbSNP
rs949783866 2615 dbSNP
rs926899715 2621 dbSNP
rs1411019223 2628 dbSNP
rs958295348 2629 dbSNP
rs1451497532 2636 dbSNP
rs182635888 2639 dbSNP
rs1407133143 2642 dbSNP
rs1347077220 2644 dbSNP
rs1045790411 2647 dbSNP
rs755337489 2653 dbSNP
rs557105232 2655 dbSNP
rs372154375 2663 dbSNP
rs905636386 2665 dbSNP
rs1041451730 2671 dbSNP
rs1363148088 2681 dbSNP
rs1001219214 2684 dbSNP
rs912279531 2685 dbSNP
rs1198992224 2690 dbSNP
rs943908005 2693 dbSNP
rs1450041426 2694 dbSNP
rs1039510133 2696 dbSNP
rs1263989532 2702 dbSNP
rs1415072148 2704 dbSNP
rs899772329 2705 dbSNP
rs1485860092 2708 dbSNP
rs1266774063 2711 dbSNP
rs779408496 2711 dbSNP
rs1225819822 2719 dbSNP
rs894675242 2722 dbSNP
rs1033813743 2729 dbSNP
rs1282996604 2731 dbSNP
rs1222567458 2732 dbSNP
rs1328977871 2736 dbSNP
rs931233902 2740 dbSNP
rs551562213 2746 dbSNP
rs1383533233 2747 dbSNP
rs1048762638 2754 dbSNP
rs899307922 2758 dbSNP
rs141739197 2764 dbSNP
rs569817409 2769 dbSNP
rs537375854 2775 dbSNP
rs376505753 2776 dbSNP
rs1026607397 2780 dbSNP
rs1477189448 2786 dbSNP
rs1025096258 2792 dbSNP
rs574217953 2795 dbSNP
rs758039202 2802 dbSNP
rs1019334381 2807 dbSNP
rs964809260 2808 dbSNP
rs575207070 2809 dbSNP
rs974784432 2809 dbSNP
rs1002395924 2811 dbSNP
rs777344434 2822 dbSNP
rs147776138 2827 dbSNP
rs958418251 2829 dbSNP
rs989766772 2833 dbSNP
rs1454548468 2835 dbSNP
rs1021585865 2842 dbSNP
rs1335903452 2843 dbSNP
rs1412539137 2848 dbSNP
rs1398276947 2859 dbSNP
rs967078209 2860 dbSNP
rs1168728051 2870 dbSNP
rs1461625543 2876 dbSNP
rs949982097 2878 dbSNP
rs1204751300 2881 dbSNP
rs558476638 2885 dbSNP
rs200172783 2886 dbSNP
rs943786283 2902 dbSNP
rs573461599 2908 dbSNP
rs540185243 2911 dbSNP
rs1171175488 2914 dbSNP
rs937101341 2918 dbSNP
rs1196045494 2921 dbSNP
rs1340978059 2928 dbSNP
rs1376789154 2935 dbSNP
rs1247511817 2939 dbSNP
rs1038120044 2940 dbSNP
rs1360155637 2940 dbSNP
rs114491694 2942 dbSNP
rs1048322442 2956 dbSNP
rs975395512 2959 dbSNP
rs887014391 2964 dbSNP
rs886705981 2974 dbSNP
rs1368935148 2982 dbSNP
rs1165623943 2985 dbSNP
rs1009539748 2997 dbSNP
rs1384627305 2998 dbSNP
rs549379388 3005 dbSNP
rs770462030 3013 dbSNP
rs1046432174 3017 dbSNP
rs573655456 3046 dbSNP
rs146246607 3047 dbSNP
rs781043278 3050 dbSNP
rs1482556221 3054 dbSNP
rs1249153921 3055 dbSNP
rs1490373847 3060 dbSNP
rs567700011 3060 dbSNP
rs1288466469 3062 dbSNP
rs1226567629 3065 dbSNP
rs138774343 3067 dbSNP
rs1305677575 3080 dbSNP
rs1348771057 3084 dbSNP
rs769787255 3086 dbSNP
rs1227924990 3090 dbSNP
rs1227553491 3095 dbSNP
rs913035234 3096 dbSNP
rs1249843599 3111 dbSNP
rs764791044 3121 dbSNP
rs971343117 3121 dbSNP
rs1321640508 3122 dbSNP
rs1021235142 3125 dbSNP
rs1158417138 3128 dbSNP
rs966914514 3128 dbSNP
rs937048730 3132 dbSNP
rs1201161137 3134 dbSNP
rs1490399707 3137 dbSNP
rs1245674778 3139 dbSNP
rs775320879 3142 dbSNP
rs1284878266 3162 dbSNP
rs1037982718 3167 dbSNP
rs535116759 3169 dbSNP
rs762702089 3170 dbSNP
rs533200505 3177 dbSNP
rs919706899 3178 dbSNP
rs975133584 3188 dbSNP
rs1273210654 3191 dbSNP
rs1467952613 3196 dbSNP
rs1345790736 3197 dbSNP
rs920987718 3199 dbSNP
rs188778695 3200 dbSNP
rs578149414 3214 dbSNP
rs1047908837 3215 dbSNP
rs1396350019 3218 dbSNP
rs149380532 3221 dbSNP
rs1433468874 3227 dbSNP
rs144750452 3231 dbSNP
rs546938526 3232 dbSNP
rs1242143490 3233 dbSNP
rs1187889037 3236 dbSNP
rs1463467605 3241 dbSNP
rs900751224 3243 dbSNP
rs79461434 3244 dbSNP
rs1311896592 3246 dbSNP
rs1046314383 3249 dbSNP
rs996200248 3254 dbSNP
rs772288237 3265 dbSNP
rs1032996736 3268 dbSNP
rs538819907 3273 dbSNP
rs1385602856 3283 dbSNP
rs1010699250 3285 dbSNP
rs1465860935 3289 dbSNP
rs1357730073 3292 dbSNP
rs1439331579 3294 dbSNP
rs529324087 3298 dbSNP
rs148501644 3305 dbSNP
rs569106359 3317 dbSNP
rs1055229666 3320 dbSNP
rs893869896 3328 dbSNP
rs1371738699 3333 dbSNP
rs1390297988 3336 dbSNP
rs1187369340 3341 dbSNP
rs971673890 3344 dbSNP
rs766665160 3345 dbSNP
rs1244885988 3352 dbSNP
rs1184051531 3353 dbSNP
rs1011096876 3360 dbSNP
rs981296215 3364 dbSNP
rs363645 3368 dbSNP
rs766578222 3378 dbSNP
rs1274076107 3381 dbSNP
rs1226267759 3384 dbSNP
rs1361597975 3385 dbSNP
rs958603561 3386 dbSNP
rs973724200 3397 dbSNP
rs1377477803 3403 dbSNP
rs1009110818 3404 dbSNP
rs1443991615 3406 dbSNP
rs1309464534 3409 dbSNP
rs145392045 3420 dbSNP
rs965030893 3421 dbSNP
rs754030257 3425 dbSNP
rs1028099519 3431 dbSNP
rs1333969015 3436 dbSNP
rs952569468 3445 dbSNP
rs984006677 3451 dbSNP
rs908384468 3453 dbSNP
rs1411406196 3454 dbSNP
rs1047217682 3463 dbSNP
rs1178702868 3472 dbSNP
rs1254816713 3475 dbSNP
rs567119206 3484 dbSNP
rs1490867883 3485 dbSNP
rs1468505880 3487 dbSNP
rs1292543997 3500 dbSNP
rs1040544537 3504 dbSNP
rs534249787 3505 dbSNP
rs961162213 3507 dbSNP
rs900782525 3509 dbSNP
rs1309684099 3517 dbSNP
rs982043911 3520 dbSNP
rs116046653 3532 dbSNP
rs1054464519 3534 dbSNP
rs938022715 3536 dbSNP
rs1407560171 3537 dbSNP
rs1366929500 3538 dbSNP
rs575826410 3544 dbSNP
rs1417571926 3549 dbSNP
rs1161116096 3553 dbSNP
rs1366632899 3553 dbSNP
rs1472804482 3570 dbSNP
rs754653145 3571 dbSNP
rs1410892675 3572 dbSNP
rs1180332967 3573 dbSNP
rs780667096 3574 dbSNP
rs1268208267 3579 dbSNP
rs1395887422 3582 dbSNP
rs1457225702 3589 dbSNP
rs1487832834 3600 dbSNP
rs893094352 3601 dbSNP
rs1364256175 3614 dbSNP
rs1010232253 3624 dbSNP
rs1328927335 3626 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000357877.2 | 3UTR | UCAAGACACACUUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000357877.2 | 3UTR | UCAAGACACACUUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-216b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT071722 CCNK cyclin K 2 2
MIRT074768 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT101407 SSR1 signal sequence receptor subunit 1 2 2
MIRT241289 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 4
MIRT268292 CCND1 cyclin D1 2 8
MIRT445347 IFNA6 interferon alpha 6 2 2
MIRT446663 MXI1 MAX interactor 1, dimerization protein 2 4
MIRT447595 MSH3 mutS homolog 3 2 2
MIRT448485 SEMA4F ssemaphorin 4F 2 2
MIRT450309 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT451850 TXNDC5 thioredoxin domain containing 5 2 2
MIRT483613 SMC5 structural maintenance of chromosomes 5 2 2
MIRT485633 EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 2 2
MIRT499766 CIRH1A UTP4, small subunit processome component 2 6
MIRT503337 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT513007 MAN1A2 mannosidase alpha class 1A member 2 2 2
MIRT513529 RHOQ ras homolog family member Q 2 4
MIRT521499 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT524335 CRK CRK proto-oncogene, adaptor protein 2 4
MIRT524731 BRI3BP BRI3 binding protein 2 8
MIRT525326 SNX29 sorting nexin 29 2 2
MIRT526264 CCDC169 coiled-coil domain containing 169 2 2
MIRT527428 NRL neural retina leucine zipper 2 2
MIRT527512 ZNF134 zinc finger protein 134 2 2
MIRT528881 ATF3 activating transcription factor 3 2 2
MIRT529578 IGBP1 immunoglobulin binding protein 1 2 4
MIRT531122 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT531341 TGIF2LX TGFB induced factor homeobox 2 like, X-linked 2 2
MIRT532433 DHX33 DEAH-box helicase 33 2 2
MIRT534032 STX7 syntaxin 7 2 2
MIRT534538 SACS sacsin molecular chaperone 2 4
MIRT538886 BRWD3 bromodomain and WD repeat domain containing 3 2 2
MIRT539628 CD19 CD19 molecule 2 8
MIRT540327 ATAT1 alpha tubulin acetyltransferase 1 2 8
MIRT540353 OCLN occludin 2 6
MIRT540699 ATG10 autophagy related 10 2 4
MIRT541033 STRBP spermatid perinuclear RNA binding protein 2 8
MIRT541945 NBPF10 NBPF member 10 2 4
MIRT543505 PLS1 plastin 1 2 2
MIRT551164 UBTF upstream binding transcription factor, RNA polymerase I 2 4
MIRT551790 ZNF117 zinc finger protein 117 2 4
MIRT553227 TWF1 twinfilin actin binding protein 1 2 2
MIRT559622 AKIRIN2 akirin 2 2 2
MIRT559719 ADORA2B adenosine A2b receptor 2 2
MIRT564600 ZNF781 zinc finger protein 781 2 2
MIRT567015 KLHL15 kelch like family member 15 2 2
MIRT569564 C7orf26 chromosome 7 open reading frame 26 2 2
MIRT572155 DDX3X DEAD-box helicase 3, X-linked 2 2
MIRT575399 Zdhhc22 zinc finger, DHHC-type containing 22 2 5
MIRT607322 PKNOX1 PBX/knotted 1 homeobox 1 2 4
MIRT607953 NFAM1 NFAT activating protein with ITAM motif 1 2 10
MIRT607979 ZDHHC22 zinc finger DHHC-type containing 22 2 7
MIRT609145 ZNF610 zinc finger protein 610 2 4
MIRT609206 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT609338 HRASLS5 HRAS like suppressor family member 5 2 2
MIRT609725 KIF5C kinesin family member 5C 2 4
MIRT610014 MED24 mediator complex subunit 24 2 4
MIRT610407 TMEM245 transmembrane protein 245 2 2
MIRT610559 NBPF14 NBPF member 14 2 2
MIRT611291 PAGR1 PAXIP1 associated glutamate rich protein 1 2 2
MIRT611399 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT611432 C11orf45 chromosome 11 open reading frame 45 2 4
MIRT611710 SLFN13 schlafen family member 13 2 2
MIRT611721 ANK3 ankyrin 3 2 2
MIRT611830 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 4
MIRT611977 ZNF175 zinc finger protein 175 2 2
MIRT612073 CEP135 centrosomal protein 135 2 4
MIRT612195 CCDC77 coiled-coil domain containing 77 2 2
MIRT612320 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT612354 TNRC6C trinucleotide repeat containing 6C 2 4
MIRT612635 PTEN phosphatase and tensin homolog 2 2
MIRT612773 MLXIP MLX interacting protein 2 4
MIRT612788 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 4
MIRT612853 JAZF1 JAZF zinc finger 1 2 2
MIRT612965 GID4 GID complex subunit 4 homolog 2 6
MIRT613132 DUSP6 dual specificity phosphatase 6 2 2
MIRT613388 AAK1 AP2 associated kinase 1 2 2
MIRT615058 CRY2 cryptochrome circadian clock 2 2 4
MIRT616046 HSPA12B heat shock protein family A (Hsp70) member 12B 2 2
MIRT617962 SEPT9 septin 9 2 2
MIRT618413 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT622448 RNF213 ring finger protein 213 2 2
MIRT623611 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT625709 SHROOM1 shroom family member 1 2 2
MIRT630646 ELK1 ELK1, ETS transcription factor 2 2
MIRT630970 KIAA2022 neurite extension and migration factor 2 2
MIRT631003 SPAG7 sperm associated antigen 7 2 2
MIRT640385 EMC1 ER membrane protein complex subunit 1 2 4
MIRT641064 WBSCR17 polypeptide N-acetylgalactosaminyltransferase 17 2 2
MIRT641780 ZDHHC7 zinc finger DHHC-type containing 7 2 4
MIRT646310 MPHOSPH8 M-phase phosphoprotein 8 2 2
MIRT646624 CENPL centromere protein L 2 2
MIRT659653 CDH2 cadherin 2 2 2
MIRT666161 SP1 Sp1 transcription factor 2 2
MIRT667638 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT668988 CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2 2
MIRT680949 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT695238 PBK PDZ binding kinase 2 2
MIRT700036 RPL22 ribosomal protein L22 2 2
MIRT707685 GPR50 G protein-coupled receptor 50 2 2
MIRT709324 HMBOX1 homeobox containing 1 2 2
MIRT710176 MTRF1L mitochondrial translational release factor 1 like 2 2
MIRT712007 F9 coagulation factor IX 2 2
MIRT714219 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT714496 HSPA4 heat shock protein family A (Hsp70) member 4 2 2
MIRT714575 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2 2
MIRT715982 TFRC transferrin receptor 2 2
MIRT717870 TRAPPC3L trafficking protein particle complex 3 like 2 2
MIRT718289 MINA ribosomal oxygenase 2 2 2
MIRT725200 PTRF caveolae associated protein 1 2 2
MIRT737338 TPX2 TPX2, microtubule nucleation factor 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-216b Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-216b 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) NULL 15625 Microarray embryos 22921993 2012 up-regulated
miR-216b Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Quantitative real-time PCR human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Curcumin NULL 969516 Quantitative real-time PCR Y79 RB cells. 22510010 2012 down-regulated
miR-216b Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-216b Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-216b Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-216b-3p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-216b-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-216b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

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