miRTarBase - #MIRT448635


—
pre-miRNA Information
pre-miRNA hsa-mir-7515   
Genomic Coordinates chr2: 6650373 - 6650439
Description Homo sapiens miR-7515 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-7515
Sequence 46| AGAAGGGAAGAUGGUGAC |63
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1451879371 1 dbSNP
rs576086800 3 dbSNP
rs753372632 5 dbSNP
rs1337497055 7 dbSNP
rs1405449301 9 dbSNP
rs1032296398 10 dbSNP
rs960195576 12 dbSNP
rs1470711310 14 dbSNP
Putative Targets

Gene Information
Gene Symbol ONECUT1   
Synonyms HNF-6, HNF6, HNF6A
Description one cut homeobox 1
Transcript NM_004498   
Expression
Putative miRNA Targets on ONECUT1
3'UTR of ONECUT1
(miRNA target sites are highlighted)		 
>ONECUT1|NM_004498|3'UTR
   1 AGGAAGAACCACAAACTAAAACCTCGGTGGAAAAGCTTTAAATTAAAAAAAATTTTTAAAAGACCAGGACCTCAAGATAG
  81 CAGGTTTATACTTAGAAATATTTGAAGAAAAAAAAGCGTTATTTATAGTCCAAAGAAACCAAAGACTTAGCTCACCTGCA
 161 TTCTGACTTTGTTTGGAGACACACACTTCAGCAGGGCGGCGACTTGGCAAGACAAATGATGAGCAGGAAAACACCACTGG
 241 ATCTCACACCTTCAATCCATGACCATCCTCGCTGTGCTTGGCTGTTTAGTGGTTTGGAGCATAGTGATTTTGAGCCATTG
 321 AGCGGACATCTTTTAAGATCGAACTTTCTCATCTGTTCTACCATGCCACGAAGGTGTATGGTGTCTCAGTACTACCACCA
 401 CCAGTGGTTACAGACTTAGGCAGAGCTGGTCTTCAGAAATGGTTGTTCTATAGGAGTGCAACCAACATGGTATGGGGTTG
 481 TCTGAGTTCATTGGATTAGGAGTGTGATTTTGCTCGTCTAGCCTAACGTTTGAACCTGCCAGGCCCGCAACCTAAATGCA
 561 GATTCAAACCCAGCAAAGAAAATTTGAATGAC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' caGUGG--UAGAAG---GGAAGa 5'
            |||:  ||| ||   ||||| 
Target 5' acCACTGGATC-TCACACCTTCa 3'
 233 - 254 105.00 -9.60
2 
miRNA  3' cagUGGUAGA--AGGGAAGa 5'
             ||: |||  ||: ||| 
Target 5' cgaACTTTCTCATCTGTTCt 3'
 340 - 359 105.00 -7.70
3 
miRNA  3' cagUGGUAGAAGGGAaga 5'
             |||||| || ||   
Target 5' atgACCATCCTCGCTgtg 3'
 259 - 276 95.00 -10.52
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30468805 16 COSMIC
COSN13627976 25 COSMIC
COSN30476201 35 COSMIC
COSN30125052 44 COSMIC
COSN28851129 52 COSMIC
COSN30504103 52 COSMIC
COSN17393065 53 COSMIC
COSN30570671 53 COSMIC
COSN26987484 54 COSMIC
COSN20078230 57 COSMIC
COSN13627972 58 COSMIC
COSN31662491 59 COSMIC
COSN30486242 72 COSMIC
COSN29157886 90 COSMIC
COSN22785172 107 COSMIC
COSN19749121 147 COSMIC
COSN26553730 197 COSMIC
COSN28196123 341 COSMIC
COSN6544433 413 COSMIC
COSN6275486 450 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1457757096 5 dbSNP
rs763134373 6 dbSNP
rs1190450297 9 dbSNP
rs369001456 10 dbSNP
rs958020694 11 dbSNP
rs773588372 20 dbSNP
rs770099603 23 dbSNP
rs746802059 25 dbSNP
rs1437891713 26 dbSNP
rs549715705 27 dbSNP
rs376178069 32 dbSNP
rs371619289 33 dbSNP
rs778340214 44 dbSNP
rs748759186 45 dbSNP
rs561632497 51 dbSNP
rs902695663 52 dbSNP
rs1292767890 53 dbSNP
rs563361433 53 dbSNP
rs1014008167 55 dbSNP
rs1351234400 57 dbSNP
rs527423409 58 dbSNP
rs1353024705 60 dbSNP
rs979588458 61 dbSNP
rs968630213 65 dbSNP
rs1200840225 71 dbSNP
rs1172867830 74 dbSNP
rs1280565695 83 dbSNP
rs559910926 92 dbSNP
rs138740702 99 dbSNP
rs937018239 101 dbSNP
rs1012472878 108 dbSNP
rs909530107 109 dbSNP
rs1186349555 110 dbSNP
rs1048325360 111 dbSNP
rs1035016443 113 dbSNP
rs577475888 115 dbSNP
rs1005374338 116 dbSNP
rs1427805298 116 dbSNP
rs886486585 116 dbSNP
rs1049617925 117 dbSNP
rs77467276 118 dbSNP
rs1371244573 120 dbSNP
rs898347884 126 dbSNP
rs1306350501 128 dbSNP
rs918432479 132 dbSNP
rs976951036 137 dbSNP
rs1479437726 139 dbSNP
rs1276420301 145 dbSNP
rs1252775804 155 dbSNP
rs965179278 161 dbSNP
rs911337559 165 dbSNP
rs1275334600 173 dbSNP
rs985493025 177 dbSNP
rs1202414112 184 dbSNP
rs912225882 187 dbSNP
rs958052055 197 dbSNP
rs544566533 198 dbSNP
rs367893918 200 dbSNP
rs967325858 201 dbSNP
rs1025224624 213 dbSNP
rs1270732598 217 dbSNP
rs1235020160 218 dbSNP
rs1173551566 221 dbSNP
rs934996585 223 dbSNP
rs1431637657 232 dbSNP
rs1166828969 233 dbSNP
rs1048965 234 dbSNP
rs1048966 235 dbSNP
rs1395982165 236 dbSNP
rs923680288 241 dbSNP
rs1325824738 247 dbSNP
rs1329122661 258 dbSNP
rs1013796511 259 dbSNP
rs1439909321 265 dbSNP
rs1344266596 269 dbSNP
rs145828223 271 dbSNP
rs555767850 272 dbSNP
rs979605905 274 dbSNP
rs1356482522 290 dbSNP
rs895302750 294 dbSNP
rs968222860 297 dbSNP
rs1264903325 308 dbSNP
rs534279806 315 dbSNP
rs1467376092 320 dbSNP
rs1322281561 321 dbSNP
rs573376160 323 dbSNP
rs1023783259 324 dbSNP
rs1001261183 328 dbSNP
rs888132351 337 dbSNP
rs373398785 340 dbSNP
rs1372548504 341 dbSNP
rs929909598 344 dbSNP
rs960982709 348 dbSNP
rs1333681038 350 dbSNP
rs1447808586 361 dbSNP
rs142172040 369 dbSNP
rs1004849548 370 dbSNP
rs150995910 378 dbSNP
rs142611685 380 dbSNP
rs911032875 400 dbSNP
rs1294849663 418 dbSNP
rs775548574 419 dbSNP
rs1340534001 425 dbSNP
rs536179692 432 dbSNP
rs776779197 446 dbSNP
rs771058685 450 dbSNP
rs567140621 467 dbSNP
rs549008271 477 dbSNP
rs1467779464 485 dbSNP
rs1466562858 486 dbSNP
rs1185284931 488 dbSNP
rs1261654533 494 dbSNP
rs898318075 502 dbSNP
rs1250544943 512 dbSNP
rs1189744084 515 dbSNP
rs747088745 516 dbSNP
rs1474988352 518 dbSNP
rs1160229976 521 dbSNP
rs978538137 522 dbSNP
rs148911583 527 dbSNP
rs145605473 528 dbSNP
rs1309988888 534 dbSNP
rs528220158 535 dbSNP
rs959545995 542 dbSNP
rs1241092365 543 dbSNP
rs747995270 546 dbSNP
rs532981843 547 dbSNP
rs185273112 557 dbSNP
rs1388667760 573 dbSNP
rs1392072283 579 dbSNP
rs888152037 582 dbSNP
rs1288742151 583 dbSNP
rs1026730122 585 dbSNP
rs946499491 600 dbSNP
rs1414480312 606 dbSNP
rs1417017369 612 dbSNP
rs1158148149 621 dbSNP
rs1378088822 622 dbSNP
rs544165440 626 dbSNP
rs994271213 634 dbSNP
rs1467506253 636 dbSNP
rs1452268225 638 dbSNP
rs916743307 644 dbSNP
rs2440333 658 dbSNP
rs1040960535 660 dbSNP
rs1392922008 661 dbSNP
rs1309396261 672 dbSNP
rs1200364257 679 dbSNP
rs1370764295 679 dbSNP
rs1306708725 680 dbSNP
rs1313189864 705 dbSNP
rs745927085 706 dbSNP
rs943932173 718 dbSNP
rs1236059808 719 dbSNP
rs889626584 720 dbSNP
rs984126907 728 dbSNP
rs950728292 738 dbSNP
rs545717039 747 dbSNP
rs115057815 751 dbSNP
rs575395500 759 dbSNP
rs1479795348 766 dbSNP
rs1486823275 779 dbSNP
rs749003600 785 dbSNP
rs540639380 786 dbSNP
rs1347426929 790 dbSNP
rs1171670107 793 dbSNP
rs376479431 800 dbSNP
rs1006694338 806 dbSNP
rs1169960027 810 dbSNP
rs1235720309 813 dbSNP
rs1352312439 816 dbSNP
rs1331686928 823 dbSNP
rs1440987289 828 dbSNP
rs754634847 838 dbSNP
rs1368728565 845 dbSNP
rs1443579043 856 dbSNP
rs917900357 862 dbSNP
rs191654800 868 dbSNP
rs868105558 882 dbSNP
rs546344008 892 dbSNP
rs1033848520 916 dbSNP
rs984994977 920 dbSNP
rs1363061746 925 dbSNP
rs952237469 930 dbSNP
rs1299151042 932 dbSNP
rs755721630 937 dbSNP
rs993909867 944 dbSNP
rs896828356 945 dbSNP
rs1478152304 948 dbSNP
rs1043821597 953 dbSNP
rs1371953472 955 dbSNP
rs1190477334 973 dbSNP
rs1416761430 976 dbSNP
rs1408918965 979 dbSNP
rs1019208645 983 dbSNP
rs1190422781 991 dbSNP
rs372008074 1000 dbSNP
rs946386759 1005 dbSNP
rs1324329562 1008 dbSNP
rs1478748024 1042 dbSNP
rs1370791192 1043 dbSNP
rs867643627 1050 dbSNP
rs889740047 1055 dbSNP
rs1397066253 1061 dbSNP
rs1049625575 1064 dbSNP
rs1272497158 1070 dbSNP
rs1359940395 1074 dbSNP
rs1214077555 1077 dbSNP
rs936531108 1080 dbSNP
rs1186945318 1088 dbSNP
rs1337250664 1097 dbSNP
rs1212107460 1102 dbSNP
rs367880026 1104 dbSNP
rs1054813028 1121 dbSNP
rs1280483326 1125 dbSNP
rs1465229644 1128 dbSNP
rs749927125 1132 dbSNP
rs928145756 1168 dbSNP
rs983706892 1182 dbSNP
rs1474755612 1193 dbSNP
rs951067102 1196 dbSNP
rs1415451374 1197 dbSNP
rs1474009314 1199 dbSNP
rs903665931 1204 dbSNP
rs542070196 1213 dbSNP
rs1163812920 1221 dbSNP
rs1394201054 1223 dbSNP
rs1042883778 1233 dbSNP
rs1343955980 1238 dbSNP
rs945451835 1242 dbSNP
rs1250811686 1244 dbSNP
rs1284829004 1248 dbSNP
rs1357489126 1256 dbSNP
rs1231677387 1263 dbSNP
rs539139931 1263 dbSNP
rs1225389927 1264 dbSNP
rs917931805 1266 dbSNP
rs1279448924 1268 dbSNP
rs1414725626 1269 dbSNP
rs1446382176 1281 dbSNP
rs568210461 1284 dbSNP
rs1353882653 1287 dbSNP
rs12443361 1289 dbSNP
rs964715065 1302 dbSNP
rs544512697 1317 dbSNP
rs35744646 1341 dbSNP
rs1484443333 1344 dbSNP
rs767090462 1345 dbSNP
rs1412278373 1350 dbSNP
rs747407414 1360 dbSNP
rs987574720 1361 dbSNP
rs1160687671 1364 dbSNP
rs937989908 1366 dbSNP
rs1400601432 1367 dbSNP
rs1335523694 1382 dbSNP
rs1377334883 1383 dbSNP
rs1432860577 1392 dbSNP
rs1312430819 1396 dbSNP
rs955176133 1403 dbSNP
rs1029940302 1412 dbSNP
rs1277535877 1422 dbSNP
rs1466787912 1424 dbSNP
rs1423742539 1425 dbSNP
rs114760715 1426 dbSNP
rs143611165 1439 dbSNP
rs758668447 1440 dbSNP
rs1188059143 1446 dbSNP
rs1010497597 1449 dbSNP
rs919406622 1452 dbSNP
rs1252041382 1453 dbSNP
rs894830590 1458 dbSNP
rs1054783947 1460 dbSNP
rs1179268488 1490 dbSNP
rs1250158517 1496 dbSNP
rs1196812392 1501 dbSNP
rs1469995461 1506 dbSNP
rs972904308 1508 dbSNP
rs140005071 1518 dbSNP
rs906692599 1525 dbSNP
rs1173114493 1549 dbSNP
rs867278846 1552 dbSNP
rs1371298469 1557 dbSNP
rs568738756 1560 dbSNP
rs1233162266 1562 dbSNP
rs1393331232 1569 dbSNP
rs554903136 1604 dbSNP
rs1334934884 1620 dbSNP
rs1286296243 1621 dbSNP
rs1305453328 1635 dbSNP
rs1048401729 1646 dbSNP
rs929494956 1653 dbSNP
rs1449264888 1660 dbSNP
rs1334795058 1661 dbSNP
rs1326382820 1662 dbSNP
rs1448542779 1663 dbSNP
rs533559456 1672 dbSNP
rs1193700594 1673 dbSNP
rs149746818 1673 dbSNP
rs398118851 1673 dbSNP
rs566547971 1673 dbSNP
rs1194687470 1677 dbSNP
rs1163611372 1679 dbSNP
rs115880505 1680 dbSNP
rs1373714887 1686 dbSNP
rs1463645715 1690 dbSNP
rs1415926821 1693 dbSNP
rs1163620174 1705 dbSNP
rs973664946 1710 dbSNP
rs758978369 1720 dbSNP
rs1007882573 1721 dbSNP
rs1392087256 1722 dbSNP
rs1188414462 1723 dbSNP
rs953702059 1733 dbSNP
rs910581950 1736 dbSNP
rs1028221868 1737 dbSNP
rs80189829 1738 dbSNP
rs1356638726 1739 dbSNP
rs1238812224 1743 dbSNP
rs1275404789 1749 dbSNP
rs1031756725 1750 dbSNP
rs903697323 1764 dbSNP
rs1042189230 1767 dbSNP
rs1191162624 1769 dbSNP
rs1292717938 1778 dbSNP
rs1010069191 1782 dbSNP
rs966580391 1783 dbSNP
rs1022142441 1789 dbSNP
rs1391994285 1800 dbSNP
rs1307577250 1803 dbSNP
rs1387087475 1817 dbSNP
rs533086195 1819 dbSNP
rs1241806516 1828 dbSNP
rs753082114 1830 dbSNP
rs1056551890 1834 dbSNP
rs1340592099 1845 dbSNP
rs1010801837 1851 dbSNP
rs1351532305 1854 dbSNP
rs894801156 1867 dbSNP
rs1333073730 1873 dbSNP
rs1487558992 1882 dbSNP
rs938021033 1894 dbSNP
rs926590876 1896 dbSNP
rs1203946269 1897 dbSNP
rs1261095275 1903 dbSNP
rs1486070979 1912 dbSNP
rs1003243184 1915 dbSNP
rs1415955455 1920 dbSNP
rs1400044866 1924 dbSNP
rs1405471226 1926 dbSNP
rs1049792640 1941 dbSNP
rs1365370065 1942 dbSNP
rs1451499335 1946 dbSNP
rs1047481950 1950 dbSNP
rs1375509714 1952 dbSNP
rs568950531 1955 dbSNP
rs1310627008 1957 dbSNP
rs899349805 1961 dbSNP
rs769798992 1962 dbSNP
rs765650205 1965 dbSNP
rs759808418 1967 dbSNP
rs188696026 1969 dbSNP
rs1248534742 1972 dbSNP
rs972300139 1974 dbSNP
rs910549528 1978 dbSNP
rs776906576 1985 dbSNP
rs183473251 1989 dbSNP
rs1446959520 1997 dbSNP
rs760792842 1998 dbSNP
rs552920992 2008 dbSNP
rs1353968377 2010 dbSNP
rs1252399020 2012 dbSNP
rs1417145065 2013 dbSNP
rs953732971 2014 dbSNP
rs1395617826 2016 dbSNP
rs1435998601 2018 dbSNP
rs1171230161 2021 dbSNP
rs7174499 2032 dbSNP
rs1462152954 2034 dbSNP
rs966925535 2035 dbSNP
rs915104581 2039 dbSNP
rs1274958355 2045 dbSNP
rs1390032539 2051 dbSNP
rs1309115668 2072 dbSNP
rs1001199170 2081 dbSNP
rs1429879426 2089 dbSNP
rs967952442 2090 dbSNP
rs1278242215 2097 dbSNP
rs1343408788 2103 dbSNP
rs1021286785 2109 dbSNP
rs959320843 2116 dbSNP
rs771978761 2126 dbSNP
rs1033561673 2135 dbSNP
rs1176439970 2135 dbSNP
rs1003587454 2147 dbSNP
rs1299773082 2148 dbSNP
rs540600886 2150 dbSNP
rs1191714313 2151 dbSNP
rs1009435188 2159 dbSNP
rs1393955281 2160 dbSNP
rs896305589 2166 dbSNP
rs1056584067 2169 dbSNP
rs1171996843 2171 dbSNP
rs77404602 2189 dbSNP
rs1374642993 2196 dbSNP
rs1331070064 2201 dbSNP
rs1395726272 2207 dbSNP
rs1301956202 2211 dbSNP
rs2440334 2221 dbSNP
rs1297947056 2233 dbSNP
rs1413015478 2233 dbSNP
rs9652454 2243 dbSNP
rs1049020318 2247 dbSNP
rs1204157064 2257 dbSNP
rs1273552966 2265 dbSNP
rs74016539 2265 dbSNP
rs557225205 2267 dbSNP
rs1211731928 2268 dbSNP
rs1252300053 2271 dbSNP
rs1485884724 2273 dbSNP
rs191374818 2279 dbSNP
rs1037009545 2280 dbSNP
rs1165277664 2281 dbSNP
rs1419010231 2286 dbSNP
rs944899772 2292 dbSNP
rs1007814419 2295 dbSNP
rs1349841678 2296 dbSNP
rs1196286308 2302 dbSNP
rs1290689515 2304 dbSNP
rs6493579 2305 dbSNP
rs1294200700 2306 dbSNP
rs144347456 2312 dbSNP
rs1207536015 2316 dbSNP
rs1231257157 2325 dbSNP
rs1288994389 2339 dbSNP
rs1313611825 2341 dbSNP
rs1278682403 2343 dbSNP
rs546815804 2355 dbSNP
rs1338326976 2356 dbSNP
rs188647260 2367 dbSNP
rs566118372 2368 dbSNP
rs1259187204 2369 dbSNP
rs1476368436 2371 dbSNP
rs796845623 2372 dbSNP
rs968108079 2377 dbSNP
rs557375012 2390 dbSNP
rs989233840 2392 dbSNP
rs1300891748 2404 dbSNP
rs1464717008 2409 dbSNP
rs1313667005 2411 dbSNP
rs768560804 2412 dbSNP
rs1357623356 2413 dbSNP
rs1413218162 2418 dbSNP
rs1283347642 2419 dbSNP
rs749058349 2427 dbSNP
rs1361159929 2429 dbSNP
rs1176873440 2430 dbSNP
rs959207060 2444 dbSNP
rs926514555 2448 dbSNP
rs1421595898 2449 dbSNP
rs28593251 2450 dbSNP
rs539159133 2461 dbSNP
rs1352252460 2464 dbSNP
rs1173370037 2473 dbSNP
rs1281962716 2479 dbSNP
rs6493578 2484 dbSNP
rs1257194999 2487 dbSNP
rs1034819373 2491 dbSNP
rs970781752 2492 dbSNP
rs1179407740 2493 dbSNP
rs1406461237 2494 dbSNP
rs1002294423 2498 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796038. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796038
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000560699.2 | 3UTR | UCAAGAUUUACUAAAAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
116 hsa-miR-7515 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT063460 SKI SKI proto-oncogene 2 4
MIRT089615 MAT2A methionine adenosyltransferase 2A 2 10
MIRT100238 PRR3 proline rich 3 2 4
MIRT159239 NRBP1 nuclear receptor binding protein 1 2 2
MIRT183526 BTG2 BTG anti-proliferation factor 2 2 2
MIRT266866 SLC25A44 solute carrier family 25 member 44 2 2
MIRT304116 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 4
MIRT331077 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT350659 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT438442 MET MET proto-oncogene, receptor tyrosine kinase 3 1
MIRT443555 ZFP3 ZFP3 zinc finger protein 2 2
MIRT447969 MSH6 mutS homolog 6 2 2
MIRT448635 ONECUT1 one cut homeobox 1 2 2
MIRT451778 USP36 ubiquitin specific peptidase 36 2 2
MIRT452615 REPIN1 replication initiator 1 2 2
MIRT453433 GLG1 golgi glycoprotein 1 2 2
MIRT454015 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT454961 TPM2 tropomyosin 2 2 2
MIRT455364 KDM5C lysine demethylase 5C 2 2
MIRT455434 ID3 inhibitor of DNA binding 3, HLH protein 2 2
MIRT455456 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT455595 TAF12 TATA-box binding protein associated factor 12 2 2
MIRT455689 GLO1 glyoxalase I 2 2
MIRT455949 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT456135 SAMD10 sterile alpha motif domain containing 10 2 2
MIRT456821 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT457441 NOL10 nucleolar protein 10 2 2
MIRT458048 TSEN54 tRNA splicing endonuclease subunit 54 2 2
MIRT458237 NXPH3 neurexophilin 3 2 2
MIRT458671 GPR35 G protein-coupled receptor 35 2 2
MIRT458741 CES2 carboxylesterase 2 2 2
MIRT459102 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT459676 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT459776 IDH3A isocitrate dehydrogenase 3 (NAD(+)) alpha 2 2
MIRT461975 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT462267 TPI1 triosephosphate isomerase 1 2 2
MIRT463296 ZFP91 ZFP91 zinc finger protein 2 2
MIRT463446 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464379 URM1 ubiquitin related modifier 1 2 2
MIRT465552 TOB2 transducer of ERBB2, 2 2 2
MIRT467359 SP2 Sp2 transcription factor 2 2
MIRT467638 SLC7A5 solute carrier family 7 member 5 2 2
MIRT467795 SLC2A14 solute carrier family 2 member 14 2 2
MIRT468466 SET SET nuclear proto-oncogene 2 4
MIRT468725 SDC4 syndecan 4 2 2
MIRT468784 SCAMP5 secretory carrier membrane protein 5 2 2
MIRT469154 RNF121 ring finger protein 121 2 2
MIRT473436 MDM4 MDM4, p53 regulator 2 2
MIRT473636 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT474242 LCLAT1 lysocardiolipin acyltransferase 1 2 2
MIRT474654 KLF13 Kruppel like factor 13 2 2
MIRT475384 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475400 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT476369 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT478017 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT478459 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT478791 CRTC2 CREB regulated transcription coactivator 2 2 2
MIRT478952 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT480412 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT481455 ARRB2 arrestin beta 2 2 2
MIRT481556 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT481740 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT483592 SLC26A9 solute carrier family 26 member 9 2 2
MIRT484423 SNX19 sorting nexin 19 2 2
MIRT484727 HOXB8 homeobox B8 2 6
MIRT487419 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT487622 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT488048 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT488064 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT488587 ST7L suppression of tumorigenicity 7 like 2 2
MIRT488696 NAT9 N-acetyltransferase 9 (putative) 2 2
MIRT489175 ANKRD45 ankyrin repeat domain 45 2 4
MIRT490435 MYL9 myosin light chain 9 2 2
MIRT490452 GLUD1 glutamate dehydrogenase 1 2 2
MIRT490704 FSTL4 follistatin like 4 2 2
MIRT491038 ALPK3 alpha kinase 3 2 2
MIRT491249 HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 2 2
MIRT491632 SEMA4G semaphorin 4G 2 2
MIRT492491 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492506 RANBP10 RAN binding protein 10 2 4
MIRT493917 FAM127B retrotransposon Gag like 8A 2 4
MIRT494012 DUSP9 dual specificity phosphatase 9 2 2
MIRT499188 RBPJL recombination signal binding protein for immunoglobulin kappa J region like 2 2
MIRT499813 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT501837 NCOA2 nuclear receptor coactivator 2 2 2
MIRT504067 KCTD12 potassium channel tetramerization domain containing 12 2 4
MIRT505313 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT511829 H2AFX H2A histone family member X 2 4
MIRT515497 GTF2F1 general transcription factor IIF subunit 1 2 2
MIRT518629 NONO non-POU domain containing octamer binding 2 2
MIRT519774 ZNF354B zinc finger protein 354B 2 8
MIRT521806 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT522621 MAP7D1 MAP7 domain containing 1 2 4
MIRT532803 CLDN11 claudin 11 2 2
MIRT533783 TMEM119 transmembrane protein 119 2 2
MIRT536433 KMT2B lysine methyltransferase 2B 2 6
MIRT538700 CASP16 caspase 16, pseudogene 2 4
MIRT544603 DCAF5 DDB1 and CUL4 associated factor 5 2 2
MIRT556730 KLHL15 kelch like family member 15 2 4
MIRT560587 LCE1B late cornified envelope 1B 2 2
MIRT560617 ANKRD36 ankyrin repeat domain 36 2 2
MIRT564348 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT568925 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT570946 CPE carboxypeptidase E 2 2
MIRT571235 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT573805 FRMPD4 FERM and PDZ domain containing 4 2 2
MIRT574149 MARVELD1 MARVEL domain containing 1 2 2
MIRT575772 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT576154 Hmox1 heme oxygenase 1 2 2
MIRT611312 CA8 carbonic anhydrase 8 2 4
MIRT615891 MT1A metallothionein 1A 2 2
MIRT669589 AK2 adenylate kinase 2 2 2
MIRT687186 PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha 2 2
MIRT692711 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT701346 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT701997 MIER3 MIER family member 3 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-7 Berbamine derivative(BBMD3) NULL NULL Illumina HiSeq2000 brain 24732116 2014 down-regulated
miR-7 Curcumin NULL 969516 Microarray BxPC-3 human pancreatic carcinoma cell line 18347134 2008 down-regulated
miR-7 Enoxacin approved 3229 Quantitative real-time PCR HCT-116 and RKO colon cancer cell lines 21368194 2011 up-regulated
miR-7 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
miR-7 Aidi injection NULL NULL Microarray human breast cancer cells 21563499 2011 up-regulated
miR-7 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-7 Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 up-regulated
miR-7 Interleukin 13 (IL-13) NULL NULL Quantitative real-time PCR bronchial epithelial cells 22453679 2012 down-regulated
miR-7 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-7 Goserelin approved 47725 Microarray prostate 22674191 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-7515 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-7515 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-7515 Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-7515 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)

Error report submission