ID	Duplex structure	Position	Score	MFE
1	miRNA 3' cgggucuGGUCUCGACCGAagu 5' ||| || ||||| Target 5' tacatctCCA-AG-TGGCTcaa 3'	155 - 174	109.00	-11.50
2	miRNA 3' cgggUC-UGGUC-UCG--ACCGAAGu 5' || | ||| ||: | |:||| Target 5' aaagAGCAACAGAAGTAATTGTTTCa 3'	11 - 36	104.00	-8.20
3	miRNA 3' cgGGUCUGGUCUCGACCGAAGu 5' | ||||| | | | |||| Target 5' gcCAAGACCTGTGATTCCTTCa 3'	242 - 263	104.00	-16.70

Mutant ID	Mutant Position	Mutant Source
COSM6180901	1	COSMIC
COSN31500311	9	COSMIC
COSN30123589	23	COSMIC
COSN30148064	36	COSMIC
COSN30163300	42	COSMIC
COSN31501944	45	COSMIC
COSN30146396	68	COSMIC
COSN30185962	85	COSMIC
COSN30512173	103	COSMIC
COSN28188588	121	COSMIC
COSN21322029	367	COSMIC
COSN7672181	1114	COSMIC
COSN16744204	1199	COSMIC
COSN8085168	1601	COSMIC
COSN22632671	1621	COSMIC
COSN8085169	1969	COSMIC
COSN8577229	2025	COSMIC
COSN8085170	2051	COSMIC
COSN23361982	2075	COSMIC
COSN23654409	2363	COSMIC

Mutant ID	Mutant Position	Mutant Source
rs368564087	5	dbSNP
rs1165142721	8	dbSNP
rs1387410092	13	dbSNP
rs1325905432	15	dbSNP
rs930175126	16	dbSNP
rs1425698421	22	dbSNP
rs761918301	25	dbSNP
rs766452576	30	dbSNP
rs1460344237	31	dbSNP
rs751495430	37	dbSNP
rs746769055	38	dbSNP
rs1362901721	39	dbSNP
rs759452198	42	dbSNP
rs1057364933	46	dbSNP
rs138368316	49	dbSNP
rs1212447412	55	dbSNP
rs1467092480	74	dbSNP
rs892060644	76	dbSNP
rs1335446792	79	dbSNP
rs1233970961	81	dbSNP
rs1010209142	88	dbSNP
rs1241446613	89	dbSNP
rs1377841449	104	dbSNP
rs373101905	114	dbSNP
rs1302786182	119	dbSNP
rs1438743849	122	dbSNP
rs910166749	122	dbSNP
rs543675946	124	dbSNP
rs968749433	135	dbSNP
rs1383244110	146	dbSNP
rs1221042433	158	dbSNP
rs1455024716	160	dbSNP
rs1380466866	164	dbSNP
rs143918212	166	dbSNP
rs756677593	171	dbSNP
rs1192488328	174	dbSNP
rs532889174	175	dbSNP
rs1452003376	180	dbSNP
rs1252139413	198	dbSNP
rs552182727	201	dbSNP
rs559438281	202	dbSNP
rs528164622	205	dbSNP
rs1199479487	207	dbSNP
rs1481805195	211	dbSNP
rs1175896478	213	dbSNP
rs1250414769	214	dbSNP
rs1018402818	215	dbSNP
rs1279835730	217	dbSNP
rs1232231116	223	dbSNP
rs894476273	225	dbSNP
rs1276020340	226	dbSNP
rs950067410	243	dbSNP
rs1045861386	247	dbSNP
rs923187283	251	dbSNP
rs1320705616	266	dbSNP
rs1414946127	271	dbSNP
rs1460487406	276	dbSNP
rs903254116	280	dbSNP
rs998710338	284	dbSNP
rs115827932	287	dbSNP
rs1170664238	289	dbSNP
rs1054286689	304	dbSNP
rs983101737	307	dbSNP
rs1396362986	325	dbSNP
rs1172584241	332	dbSNP
rs1475051689	337	dbSNP
rs908881046	355	dbSNP
rs893076593	357	dbSNP
rs1416479098	365	dbSNP
rs1257137463	377	dbSNP
rs1208982141	386	dbSNP
rs1350230807	393	dbSNP
rs1291384707	395	dbSNP
rs1213997226	396	dbSNP
rs768504564	399	dbSNP
rs1007478805	400	dbSNP
rs1017915531	408	dbSNP
rs1227852722	417	dbSNP
rs568068916	426	dbSNP
rs997126835	431	dbSNP
rs1401045687	433	dbSNP
rs557563517	433	dbSNP
rs1057486969	443	dbSNP
rs938829489	443	dbSNP
rs372156029	444	dbSNP
rs1026045549	445	dbSNP
rs1185443805	445	dbSNP
rs1360480325	445	dbSNP
rs1416886301	445	dbSNP
rs1478056947	445	dbSNP
rs35145052	445	dbSNP
rs551783148	445	dbSNP
rs66557303	445	dbSNP
rs757814948	445	dbSNP
rs762951162	445	dbSNP
rs1486784148	446	dbSNP
rs1202860868	447	dbSNP
rs892012568	450	dbSNP
rs950469561	462	dbSNP
rs1436133802	463	dbSNP
rs1275793942	464	dbSNP
rs1450671459	465	dbSNP
rs1213586268	466	dbSNP
rs1010906922	468	dbSNP
rs1256064844	469	dbSNP
rs1472162775	472	dbSNP
rs1235475229	473	dbSNP
rs1186649738	475	dbSNP
rs1380934069	476	dbSNP
rs1284396290	477	dbSNP
rs1043351826	480	dbSNP
rs1421192510	481	dbSNP
rs1426294926	489	dbSNP
rs982948526	493	dbSNP
rs1169322686	494	dbSNP
rs904515024	496	dbSNP
rs1006921772	502	dbSNP
rs1436386973	509	dbSNP
rs910062109	510	dbSNP
rs1468730552	511	dbSNP
rs1240107910	516	dbSNP
rs1310961154	518	dbSNP
rs530706181	524	dbSNP
rs1468448823	526	dbSNP
rs963161939	533	dbSNP
rs1215990258	534	dbSNP
rs1313056514	536	dbSNP
rs991772540	536	dbSNP
rs376886747	542	dbSNP
rs1270913327	551	dbSNP
rs1446817554	554	dbSNP
rs916118034	560	dbSNP
rs184516299	564	dbSNP
rs1212971448	566	dbSNP
rs1350250287	573	dbSNP
rs1297172709	576	dbSNP
rs1349000619	581	dbSNP
rs1399188058	586	dbSNP
rs1382356888	591	dbSNP
rs1179375685	593	dbSNP
rs1030583555	602	dbSNP
rs763172343	610	dbSNP
rs1193412775	612	dbSNP
rs570400399	614	dbSNP
rs983766800	615	dbSNP
rs1260507462	616	dbSNP
rs1278791667	628	dbSNP
rs147242753	629	dbSNP
rs749764254	630	dbSNP
rs934724822	633	dbSNP
rs1240289501	634	dbSNP
rs1346488927	639	dbSNP
rs1301248463	648	dbSNP
rs1054913997	653	dbSNP
rs1368144775	658	dbSNP
rs892988866	659	dbSNP
rs1428343906	670	dbSNP
rs1362739888	683	dbSNP
rs1159455872	685	dbSNP
rs1007776588	687	dbSNP
rs1243283709	688	dbSNP
rs35516634	689	dbSNP
rs397704505	689	dbSNP
rs1187493915	692	dbSNP
rs1178239101	704	dbSNP
rs1038979976	705	dbSNP
rs34102486	706	dbSNP
rs1434265307	709	dbSNP
rs901740126	714	dbSNP
rs1395346116	715	dbSNP
rs1489457387	716	dbSNP
rs927016231	721	dbSNP
rs1455403773	722	dbSNP
rs1346621234	730	dbSNP
rs2974352	733	dbSNP
rs34135526	733	dbSNP
rs1025930680	734	dbSNP
rs1312737759	734	dbSNP
rs950355354	748	dbSNP
rs115285631	753	dbSNP
rs1299101179	756	dbSNP
rs913386815	757	dbSNP
rs946268256	758	dbSNP
rs1304680291	765	dbSNP
rs1466580346	766	dbSNP
rs73632785	767	dbSNP
rs962925217	775	dbSNP
rs904797960	781	dbSNP
rs1424793431	793	dbSNP
rs942652475	794	dbSNP
rs1485153604	796	dbSNP
rs774324626	797	dbSNP
rs1201719559	804	dbSNP
rs868614570	814	dbSNP
rs1483280556	820	dbSNP
rs140760620	821	dbSNP
rs1196673307	822	dbSNP
rs746072117	823	dbSNP
rs1319819678	826	dbSNP
rs73675086	827	dbSNP
rs1232397746	831	dbSNP
rs543979708	840	dbSNP
rs1025761610	842	dbSNP
rs1236942951	844	dbSNP
rs1395843755	847	dbSNP
rs1301786176	853	dbSNP
rs971638400	854	dbSNP
rs557617884	865	dbSNP
rs577609527	869	dbSNP
rs1467658303	871	dbSNP
rs981476038	873	dbSNP
rs117441223	877	dbSNP
rs112722278	878	dbSNP
rs1004743273	881	dbSNP
rs1474415549	884	dbSNP
rs1016112169	885	dbSNP
rs963277044	897	dbSNP
rs979703825	904	dbSNP
rs367760614	913	dbSNP
rs1033977566	914	dbSNP
rs1224777281	918	dbSNP
rs934625439	919	dbSNP
rs542630365	921	dbSNP
rs992978343	924	dbSNP
rs776395762	928	dbSNP
rs1044360	930	dbSNP
rs1207610642	932	dbSNP
rs1267515698	935	dbSNP
rs914627524	935	dbSNP
rs1469587751	943	dbSNP
rs946185967	948	dbSNP
rs761659595	957	dbSNP
rs978941831	958	dbSNP
rs1378345109	964	dbSNP
rs1191364716	965	dbSNP
rs541485287	970	dbSNP
rs926161002	988	dbSNP
rs765019034	989	dbSNP
rs753734328	991	dbSNP
rs149318135	1002	dbSNP
rs757141111	1007	dbSNP
rs1455692817	1014	dbSNP
rs530555654	1018	dbSNP
rs1362807340	1020	dbSNP
rs922589006	1029	dbSNP
rs1440963368	1031	dbSNP
rs1158601011	1034	dbSNP
rs773140751	1046	dbSNP
rs767886929	1048	dbSNP
rs550356263	1049	dbSNP
rs762817280	1054	dbSNP
rs1047596011	1055	dbSNP
rs887218403	1069	dbSNP
rs1350268562	1072	dbSNP
rs1284111063	1073	dbSNP
rs765877016	1077	dbSNP
rs1330841376	1079	dbSNP
rs377363406	1079	dbSNP
rs886127799	1082	dbSNP
rs1333273818	1101	dbSNP
rs1281755068	1102	dbSNP
rs570352872	1103	dbSNP
rs1005816369	1104	dbSNP
rs1016047096	1105	dbSNP
rs894869754	1106	dbSNP
rs532967290	1112	dbSNP
rs1172400124	1114	dbSNP
rs1477013607	1115	dbSNP
rs1248348950	1125	dbSNP
rs751075777	1126	dbSNP
rs1446192491	1148	dbSNP
rs1013942521	1149	dbSNP
rs1276439310	1152	dbSNP
rs1219071612	1153	dbSNP
rs546439453	1158	dbSNP
rs1279727199	1159	dbSNP
rs1211384061	1165	dbSNP
rs1023547877	1166	dbSNP
rs1217495893	1169	dbSNP
rs971522308	1170	dbSNP
rs1288744172	1172	dbSNP
rs1275924997	1175	dbSNP
rs754639666	1185	dbSNP
rs566675317	1187	dbSNP
rs1020429527	1189	dbSNP
rs981693590	1190	dbSNP
rs1183787563	1191	dbSNP
rs1332968240	1202	dbSNP
rs1412233602	1203	dbSNP
rs1427245482	1204	dbSNP
rs376406317	1205	dbSNP
rs1475001698	1206	dbSNP
rs956053211	1211	dbSNP
rs978887486	1212	dbSNP
rs1188580059	1216	dbSNP
rs1418599840	1218	dbSNP
rs753303412	1228	dbSNP
rs371201855	1229	dbSNP
rs1161646063	1231	dbSNP
rs1390348664	1236	dbSNP
rs1316522705	1239	dbSNP
rs1280504005	1241	dbSNP
rs568518959	1244	dbSNP
rs537196876	1245	dbSNP
rs557581007	1248	dbSNP
rs964242749	1252	dbSNP
rs577473085	1259	dbSNP
rs189532374	1273	dbSNP
rs1334172781	1280	dbSNP
rs974818547	1281	dbSNP
rs553678425	1284	dbSNP
rs573476036	1287	dbSNP
rs975650165	1288	dbSNP
rs922902732	1291	dbSNP
rs933962675	1293	dbSNP
rs541796349	1294	dbSNP
rs1409688840	1304	dbSNP
rs111605223	1305	dbSNP
rs1473854234	1306	dbSNP
rs1356771125	1312	dbSNP
rs1230969529	1315	dbSNP
rs753108329	1317	dbSNP
rs1047654191	1325	dbSNP
rs1181104595	1328	dbSNP
rs886347236	1331	dbSNP
rs1339732926	1336	dbSNP
rs908585505	1340	dbSNP
rs1199716654	1342	dbSNP
rs1334598925	1348	dbSNP
rs771702142	1353	dbSNP
rs941730690	1354	dbSNP
rs941451234	1356	dbSNP
rs1270546348	1369	dbSNP
rs117819320	1370	dbSNP
rs1211451125	1371	dbSNP
rs1333259115	1372	dbSNP
rs1465996468	1374	dbSNP
rs540348248	1374	dbSNP
rs898995221	1375	dbSNP
rs11379177	1376	dbSNP
rs1346432356	1376	dbSNP
rs1491539512	1376	dbSNP
rs199693651	1376	dbSNP
rs77988866	1376	dbSNP
rs11387506	1377	dbSNP
rs75767063	1377	dbSNP
rs1056096524	1386	dbSNP
rs1476213936	1392	dbSNP
rs1290103383	1398	dbSNP
rs894930726	1402	dbSNP
rs1311453968	1415	dbSNP
rs2974353	1415	dbSNP
rs753493836	1419	dbSNP
rs1447428512	1420	dbSNP
rs1368110520	1427	dbSNP
rs1291593223	1438	dbSNP
rs1019952535	1439	dbSNP
rs1350737173	1442	dbSNP
rs546404535	1444	dbSNP
rs1475826567	1446	dbSNP
rs1024691452	1465	dbSNP
rs1382254425	1472	dbSNP
rs1159271019	1475	dbSNP
rs778296377	1482	dbSNP
rs757000751	1483	dbSNP
rs1433142868	1497	dbSNP
rs1423639711	1499	dbSNP
rs999940870	1510	dbSNP
rs1269223444	1514	dbSNP
rs1488996422	1514	dbSNP
rs1369046728	1515	dbSNP
rs907388952	1516	dbSNP
rs867923010	1517	dbSNP
rs964189706	1521	dbSNP
rs376535727	1525	dbSNP
rs956271978	1543	dbSNP
rs560379339	1544	dbSNP
rs1311563814	1563	dbSNP
rs1299078203	1565	dbSNP
rs1393782248	1566	dbSNP
rs1368038189	1571	dbSNP
rs778752320	1573	dbSNP
rs955658801	1590	dbSNP
rs180731662	1594	dbSNP
rs113930407	1595	dbSNP
rs964701020	1598	dbSNP
rs908536663	1599	dbSNP
rs746641853	1600	dbSNP
rs941399380	1602	dbSNP
rs1434182860	1604	dbSNP
rs1423357455	1611	dbSNP
rs1191880485	1612	dbSNP
rs975248956	1621	dbSNP
rs1268075550	1627	dbSNP
rs1341151940	1639	dbSNP
rs1234810890	1645	dbSNP
rs1482636843	1650	dbSNP
rs1282361622	1651	dbSNP
rs1195143391	1652	dbSNP
rs749754647	1653	dbSNP
rs923332478	1655	dbSNP
rs1277357093	1661	dbSNP
rs1199805944	1665	dbSNP
rs568404533	1670	dbSNP
rs937150213	1679	dbSNP
rs1253166215	1683	dbSNP
rs933185273	1693	dbSNP
rs4737045	1697	dbSNP
rs77311848	1706	dbSNP
rs1042062424	1714	dbSNP
rs148485175	1715	dbSNP
rs1169024151	1719	dbSNP
rs1467482551	1720	dbSNP
rs779854450	1725	dbSNP
rs1425399931	1740	dbSNP
rs1193450889	1741	dbSNP
rs1174723542	1746	dbSNP
rs1422811918	1746	dbSNP
rs916235356	1748	dbSNP
rs1397429295	1752	dbSNP
rs1464927863	1753	dbSNP
rs947722652	1756	dbSNP
rs1461739702	1759	dbSNP
rs1257315749	1760	dbSNP
rs999887230	1764	dbSNP
rs1046208175	1765	dbSNP
rs10533662	1773	dbSNP
rs1384994623	1774	dbSNP
rs899598389	1777	dbSNP
rs1314965837	1779	dbSNP
rs906263864	1783	dbSNP
rs1383452553	1807	dbSNP
rs1376863926	1812	dbSNP
rs1318090822	1814	dbSNP
rs745990268	1815	dbSNP
rs772275073	1817	dbSNP
rs1401488540	1828	dbSNP
rs768379885	1835	dbSNP
rs891927352	1835	dbSNP
rs7008843	1836	dbSNP
rs1166348259	1839	dbSNP
rs1305270947	1841	dbSNP
rs543045722	1845	dbSNP
rs1250988087	1846	dbSNP
rs75611625	1846	dbSNP
rs1398226543	1850	dbSNP
rs1232378261	1856	dbSNP
rs1354543997	1866	dbSNP
rs965084185	1867	dbSNP
rs1267422949	1868	dbSNP
rs996123537	1875	dbSNP
rs78607781	1877	dbSNP
rs962665432	1880	dbSNP
rs186700921	1882	dbSNP
rs1307095495	1890	dbSNP
rs1242970921	1891	dbSNP
rs1336822404	1896	dbSNP
rs974061182	1902	dbSNP
rs1246410299	1904	dbSNP
rs1464671336	1905	dbSNP
rs879778327	1912	dbSNP
rs1294914644	1914	dbSNP
rs983283825	1919	dbSNP
rs1255226174	1920	dbSNP
rs907723144	1923	dbSNP
rs1441488598	1931	dbSNP
rs992693612	1934	dbSNP
rs1364268362	1939	dbSNP
rs1431827926	1945	dbSNP
rs189567301	1946	dbSNP
rs114469550	1952	dbSNP
rs916472670	1959	dbSNP
rs1223507700	1961	dbSNP
rs1041619898	1963	dbSNP
rs142599982	1964	dbSNP
rs1156403476	1965	dbSNP
rs1387281952	1971	dbSNP
rs181733468	1973	dbSNP
rs1274757960	1980	dbSNP
rs1046092550	1981	dbSNP
rs1327526076	1984	dbSNP
rs1333182317	1988	dbSNP
rs1054132387	1989	dbSNP
rs1365175672	1995	dbSNP
rs899545861	1998	dbSNP
rs747242243	1999	dbSNP
rs577352748	2002	dbSNP
rs561530389	2008	dbSNP
rs1385641308	2010	dbSNP
rs1052143108	2011	dbSNP
rs891975437	2012	dbSNP
rs1476962157	2013	dbSNP
rs1011714752	2021	dbSNP
rs1379168607	2029	dbSNP
rs112547698	2030	dbSNP
rs1337528909	2037	dbSNP
rs866264294	2044	dbSNP
rs1230300436	2046	dbSNP
rs1477637387	2048	dbSNP
rs1218954195	2050	dbSNP
rs772908159	2054	dbSNP
rs1266247913	2058	dbSNP
rs996174383	2065	dbSNP
rs1214504992	2066	dbSNP
rs1015773135	2068	dbSNP
rs186141267	2076	dbSNP
rs1030283236	2078	dbSNP
rs762920824	2080	dbSNP
rs1191035012	2083	dbSNP
rs1339485101	2084	dbSNP
rs1275886150	2087	dbSNP
rs1463046092	2091	dbSNP
rs1432352594	2093	dbSNP
rs1004926257	2095	dbSNP
rs1014986707	2102	dbSNP
rs190464872	2103	dbSNP
rs548728179	2105	dbSNP
rs1033641943	2112	dbSNP
rs973242242	2115	dbSNP
rs1176943605	2118	dbSNP
rs1464890536	2119	dbSNP
rs548967563	2120	dbSNP
rs1475824094	2122	dbSNP
rs959400953	2122	dbSNP
rs751885638	2128	dbSNP
rs1185453257	2149	dbSNP
rs1444668395	2154	dbSNP
rs1264267977	2180	dbSNP
rs183472669	2185	dbSNP
rs916523720	2193	dbSNP
rs969323862	2203	dbSNP
rs34559623	2204	dbSNP
rs1255834736	2209	dbSNP
rs1166607388	2213	dbSNP
rs1339601324	2215	dbSNP
rs1283123434	2237	dbSNP
rs530900108	2255	dbSNP
rs1384963805	2257	dbSNP
rs981989943	2260	dbSNP
rs971231871	2261	dbSNP
rs1445853830	2264	dbSNP
rs1347808798	2268	dbSNP
rs1172197902	2269	dbSNP
rs927615668	2274	dbSNP
rs1413296989	2276	dbSNP
rs551013376	2277	dbSNP
rs1446502300	2278	dbSNP
rs1244359014	2280	dbSNP
rs1178565565	2284	dbSNP
rs766280303	2294	dbSNP
rs773901714	2308	dbSNP
rs770145197	2310	dbSNP
rs1298604683	2321	dbSNP
rs1205614166	2324	dbSNP
rs759187449	2330	dbSNP
rs749468748	2341	dbSNP
rs534458438	2342	dbSNP
rs1407860879	2344	dbSNP
rs767143141	2346	dbSNP
rs1239349389	2348	dbSNP
rs914981491	2351	dbSNP
rs1299700921	2355	dbSNP
rs1050846917	2356	dbSNP
rs1349909047	2357	dbSNP
rs1349568242	2358	dbSNP
rs1321816068	2359	dbSNP
rs570944902	2361	dbSNP
rs947567309	2362	dbSNP
rs1158072843	2367	dbSNP
rs890887352	2368	dbSNP
rs771111626	2369	dbSNP
rs752339844	2374	dbSNP
rs900786528	2375	dbSNP
rs539969650	2384	dbSNP
rs1245834220	2387	dbSNP
rs1218928637	2394	dbSNP
rs547170583	2395	dbSNP
rs1221114770	2398	dbSNP
rs1037168219	2399	dbSNP
rs1051926232	2400	dbSNP
rs1215216985	2401	dbSNP
rs1484253328	2404	dbSNP
rs1203580597	2406	dbSNP
rs898710111	2406	dbSNP
rs890475858	2413	dbSNP
rs1251779554	2416	dbSNP
rs1224189548	2418	dbSNP
rs995709251	2419	dbSNP
rs1272795100	2421	dbSNP
rs760427599	2432	dbSNP
rs1407009730	2444	dbSNP
rs1475236733	2450	dbSNP
rs764521899	2451	dbSNP
rs754203505	2454	dbSNP
rs1015451874	2462	dbSNP
rs899244970	2463	dbSNP
rs1160461575	2469	dbSNP
rs757767504	2474	dbSNP
rs1023474846	2485	dbSNP
rs1433043302	2487	dbSNP
rs779354684	2488	dbSNP
rs566908987	2502	dbSNP
rs1411176638	2505	dbSNP
rs1014024720	2509	dbSNP
rs573214387	2513	dbSNP
rs1170729091	2518	dbSNP
rs982042213	2524	dbSNP
rs1269119529	2530	dbSNP
rs1034904531	2533	dbSNP
rs956386777	2538	dbSNP
rs1192365050	2541	dbSNP
rs146486200	2552	dbSNP
rs915016582	2558	dbSNP
rs946480561	2565	dbSNP
rs1276281762	2566	dbSNP
rs774682665	2566	dbSNP
rs1346440518	2567	dbSNP
rs967204847	2574	dbSNP
rs187049300	2577	dbSNP
rs750942028	2578	dbSNP
rs977214636	2579	dbSNP
rs1304590289	2584	dbSNP

- Cell host & microbe, 2011

Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.