miRTarBase - #MIRT449789


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pre-miRNA Information
pre-miRNA hsa-mir-1299   
Genomic Coordinates chr9: 40929010 - 40929092
Synonyms MIRN1299, hsa-mir-1299, MIR1299
Description Homo sapiens miR-1299 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1299
Sequence 62| UUCUGGAAUUCUGUGUGAGGGA |83
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1042551075 4 dbSNP
rs747216379 19 dbSNP
rs1009712608 20 dbSNP
rs796108267 21 dbSNP
rs796728500 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol C1orf109   
Synonyms -
Description chromosome 1 open reading frame 109
Transcript NM_017850   
Expression
Putative miRNA Targets on C1orf109
3'UTR of C1orf109
(miRNA target sites are highlighted)		 
>C1orf109|NM_017850|3'UTR
   1 GGAAGCTATGCGTATCTGGAGACCACGGGTACCACAGTTGAAGACTGACATTCTGAACCCTGATGTTTCTAAAGAAACGT
  81 CAGTATTTCAGTCTGACATATTTGAAACATCAGTGCCTTGAACCTTAGGACTGGGTCTTGGGGAGGATTAGCGCCTAGAT
 161 GTCTGATTTTGGAGCTGCAGCATGCCAGGCCGTGGCTGAGAGTATGTGAGCCATGCCTTGCCCTTTTCTGAGGCTCAGGG
 241 AAGTGGATGGAGCTAGAGAGACAACAGGAAAGACGGTGCTGAAGAACATAGTGTCTTTCCTCTATTGTGGACCTAAAGAG
 321 GTGGGGAAGCAAGGACAAGAGGCAAAGAGCCACACTGCCCTTGGCATCATCCAAAGCATTGTCTGGTTGACACCAGGTCC
 401 TGGTTTTGTGTCTTTTGTCAATACCTGAATCCTTGACAAAAGAAAAAGTGGTTTTGATGATTTAAAGAAATAAGGGTGAT
 481 TTTGACAGAAAATATATTTTAAAAATTTTGACCAATTGCAATAGTTATCCTCAAGCCAATTTCCAGAACCTGCCACCAGG
 561 GGGAGGTGGTGCAGCATGAATCATTCTGAATGCTTTGTCTTTGAAGTGTTCCCCTATTGCTGTTACCATCTCAGAGGAAG
 641 TAACTGGGCATGGTGAGACTCCTAAAATGACAGGAGTTTTTTTGGCCAAAGCTGGCATCTGACTTGCCACATTCCTCTGA
 721 GTCTGGAGTAGCCGCAGGGGTGGGAGAATGCCAGCCCAGAGTCAGTCCATCGGGGTTACATTTCCAAGGTCTGCTGCCTT
 801 CATCTATGTAATGGCCGTGTTACTTTCAGATCTTTCAGCTTCCCAGAGTGTTGTGGGAATCTTGGTCATTGAATGTAAAG
 881 GGACTTAGTAAAGGGTATAGATATTTTTCAAAAATGAAAATAACTTTTTTTCTTATAAGTGATAAGCTTTTATAAAGATC
 961 ATAGGAAAACTAGAAAAAATGTAAAATGTAGAAAATTGTAAAACAAACTTCATTAGAGATATTTTGATAGATACCTTTTC
1041 AGTGTCTATTTACAAATTTTTTCTTTTAATATAGATAGGGTCTCACTATATTGCCCAGCTCACTCCTGAGCTCAAGGGAT
1121 CCTCCCACCATAGCCTCCCAAAATATTGGAAATACAGGCATGAGCCACTGCTCCTGACCAATTCACAAATTTTTTTAAAG
1201 AACAAACGTGCTATCATCGATACATACTGTTAGGTTGTCTTTTTTTAAAAAACCTAATGTAATTTGTTCATCTTTTTATA
1281 TCTGTAAATATAGCTCAACACAGTTATATTCTTTTTGTGAATGTATTATATCTACAATTTACCTTTTTTCTTAGATTTTA
1361 CATGCATTTTCCCAAATCTTTGTGTTTGCCTATCTGTAAAGGTAATACATTCTGATTACAAAAAATGAAAATGTTACATA
1441 GAAATGTACCGTTATCCATCTACCAGATAACTATTATTAATAATGTGTATTTATTTTTCCAGGAATTAAAAAACATCTAT
1521 CATATAAGTATTGCAAATAAAACTTAAAAAGCAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGGAGUGUGUCUUAAGGUCUu 5'
            ||||| :|  | ||||||| 
Target 5' atCCTCAAGCCAATTTCCAGAa 3'
 527 - 548 164.00 -18.84
2 
miRNA  3' agggagugugucUUAAGGUCUu 5'
                      | ||:|||| 
Target 5' aatggccgtgttACTTTCAGAt 3'
 810 - 831 126.00 -8.10
3 
miRNA  3' agggaGUGUGUCUUAAGGUCUu 5'
               :|: :|   ||||||: 
Target 5' atgtgTATTTATTTTTCCAGGa 3'
 1483 - 1504 125.00 -9.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN8407146 2 COSMIC
COSN26600850 12 COSMIC
COSN31662810 31 COSMIC
COSN30510591 68 COSMIC
COSN16128492 69 COSMIC
COSN31612204 274 COSMIC
COSN20090205 366 COSMIC
COSN31536978 535 COSMIC
COSN29468003 561 COSMIC
COSN4750279 654 COSMIC
COSN6455245 671 COSMIC
COSN6455244 672 COSMIC
COSN10048133 772 COSMIC
COSN25385608 1188 COSMIC
rs10908369 30 GWAS
rs11264087 30 GWAS
rs11264091 30 GWAS
rs12119598 30 GWAS
rs12139097 30 GWAS
rs3762352 30 GWAS
rs3790623 30 GWAS
rs497705 30 GWAS
rs507667 30 GWAS
rs510208 30 GWAS
rs557897 30 GWAS
rs589927 30 GWAS
rs658024 30 GWAS
rs661460 30 GWAS
rs684260 30 GWAS
rs768659 30 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781477657 1 dbSNP
rs1372079724 2 dbSNP
rs372472705 5 dbSNP
rs1389806350 8 dbSNP
rs750250750 9 dbSNP
rs146821670 10 dbSNP
rs1031835108 11 dbSNP
rs374234641 12 dbSNP
rs1342712602 17 dbSNP
rs774139218 20 dbSNP
rs1248777768 21 dbSNP
rs1348767282 23 dbSNP
rs370918377 26 dbSNP
rs1219047448 27 dbSNP
rs760274537 27 dbSNP
rs1264644587 29 dbSNP
rs684260 30 dbSNP
rs1208792238 34 dbSNP
rs771787576 35 dbSNP
rs1178593717 36 dbSNP
rs1256699059 44 dbSNP
rs1235242774 50 dbSNP
rs575576456 56 dbSNP
rs879117176 62 dbSNP
rs948345307 77 dbSNP
rs776151968 78 dbSNP
rs1371682863 79 dbSNP
rs1167429846 80 dbSNP
rs1163036530 98 dbSNP
rs1038093426 108 dbSNP
rs143559169 111 dbSNP
rs1425826796 123 dbSNP
rs939788936 126 dbSNP
rs1305558984 134 dbSNP
rs553787824 152 dbSNP
rs1409340121 153 dbSNP
rs1289089473 159 dbSNP
rs749556908 183 dbSNP
rs1375717817 191 dbSNP
rs986644567 192 dbSNP
rs1311729846 195 dbSNP
rs1243013596 201 dbSNP
rs1224594597 203 dbSNP
rs1272456639 205 dbSNP
rs966863893 215 dbSNP
rs1205206833 223 dbSNP
rs878881016 226 dbSNP
rs933849559 231 dbSNP
rs1025064537 233 dbSNP
rs1013793853 236 dbSNP
rs1413518028 255 dbSNP
rs1445659580 256 dbSNP
rs139692993 261 dbSNP
rs1195421444 263 dbSNP
rs975322700 264 dbSNP
rs964655988 268 dbSNP
rs770496172 274 dbSNP
rs780948989 275 dbSNP
rs564874909 276 dbSNP
rs540214611 288 dbSNP
rs1341287154 289 dbSNP
rs756917079 291 dbSNP
rs929345051 291 dbSNP
rs1314242127 292 dbSNP
rs1440260044 298 dbSNP
rs567227620 299 dbSNP
rs1462394174 300 dbSNP
rs555460300 302 dbSNP
rs574705596 321 dbSNP
rs1388722095 329 dbSNP
rs1336991919 334 dbSNP
rs1040190778 336 dbSNP
rs1329009419 339 dbSNP
rs533734506 345 dbSNP
rs1412892327 355 dbSNP
rs1175482714 364 dbSNP
rs1390453870 365 dbSNP
rs555052239 366 dbSNP
rs1318226739 376 dbSNP
rs910460132 382 dbSNP
rs1431380836 386 dbSNP
rs1271896162 404 dbSNP
rs1032200499 412 dbSNP
rs1342231676 414 dbSNP
rs1304592638 417 dbSNP
rs1003024363 441 dbSNP
rs907383139 442 dbSNP
rs1385042158 443 dbSNP
rs1162192920 448 dbSNP
rs990247587 458 dbSNP
rs957080262 459 dbSNP
rs1023194093 476 dbSNP
rs1013183283 477 dbSNP
rs780054148 486 dbSNP
rs1244290329 495 dbSNP
rs1364443210 514 dbSNP
rs1477346715 518 dbSNP
rs150681831 521 dbSNP
rs1181266014 522 dbSNP
rs191403962 528 dbSNP
rs764881576 532 dbSNP
rs1471068478 536 dbSNP
rs1157298115 537 dbSNP
rs1387593662 548 dbSNP
rs1401123675 556 dbSNP
rs1269667819 557 dbSNP
rs971081945 560 dbSNP
rs1490443196 563 dbSNP
rs1290825537 564 dbSNP
rs1435679914 566 dbSNP
rs1283353265 576 dbSNP
rs1346920902 579 dbSNP
rs756949449 580 dbSNP
rs886850392 582 dbSNP
rs1051315010 586 dbSNP
rs1206050004 587 dbSNP
rs1013698769 596 dbSNP
rs1450335247 598 dbSNP
rs933817977 599 dbSNP
rs72915976 611 dbSNP
rs1481481411 612 dbSNP
rs550487856 613 dbSNP
rs1470651816 630 dbSNP
rs1284764152 644 dbSNP
rs529115981 645 dbSNP
rs1365321648 647 dbSNP
rs1404691548 659 dbSNP
rs1303730625 666 dbSNP
rs670692 671 dbSNP
rs539585 672 dbSNP
rs1335916871 673 dbSNP
rs35605341 673 dbSNP
rs879813962 673 dbSNP
rs1240765258 682 dbSNP
rs1281620611 684 dbSNP
rs1386230441 684 dbSNP
rs993581432 700 dbSNP
rs990152919 711 dbSNP
rs901922351 722 dbSNP
rs956256909 731 dbSNP
rs1031731933 733 dbSNP
rs775806050 734 dbSNP
rs1251175960 735 dbSNP
rs1438550650 741 dbSNP
rs569877927 746 dbSNP
rs142995614 768 dbSNP
rs111852788 769 dbSNP
rs1060038 770 dbSNP
rs1013131042 771 dbSNP
rs962949130 772 dbSNP
rs935883974 774 dbSNP
rs1219893772 778 dbSNP
rs1396669170 779 dbSNP
rs1448531646 783 dbSNP
rs1331832452 788 dbSNP
rs1339052648 792 dbSNP
rs1017227923 799 dbSNP
rs977054743 806 dbSNP
rs949836449 816 dbSNP
rs148558384 817 dbSNP
rs886795031 823 dbSNP
rs1250817534 829 dbSNP
rs992308558 833 dbSNP
rs1340201178 834 dbSNP
rs1050838955 839 dbSNP
rs1197753422 849 dbSNP
rs1254283892 856 dbSNP
rs768095118 858 dbSNP
rs1461064371 859 dbSNP
rs1183903439 864 dbSNP
rs1244763554 866 dbSNP
rs959584054 877 dbSNP
rs183128422 881 dbSNP
rs1373117047 890 dbSNP
rs556383385 898 dbSNP
rs985066348 901 dbSNP
rs1401000035 903 dbSNP
rs192039249 904 dbSNP
rs1452921379 909 dbSNP
rs952355165 924 dbSNP
rs1385509219 925 dbSNP
rs557660634 929 dbSNP
rs1295559906 932 dbSNP
rs577639657 932 dbSNP
rs1308624286 933 dbSNP
rs542028420 941 dbSNP
rs574991122 942 dbSNP
rs1323030514 951 dbSNP
rs1204617345 959 dbSNP
rs993486321 963 dbSNP
rs901954936 964 dbSNP
rs1019060065 965 dbSNP
rs946579866 968 dbSNP
rs915139913 980 dbSNP
rs1430267334 981 dbSNP
rs1196047193 982 dbSNP
rs1428003318 983 dbSNP
rs1052799954 986 dbSNP
rs57208826 989 dbSNP
rs533876084 991 dbSNP
rs1408730654 998 dbSNP
rs1054657752 999 dbSNP
rs935972958 1009 dbSNP
rs1363191856 1018 dbSNP
rs903092038 1033 dbSNP
rs1399512760 1034 dbSNP
rs142743701 1035 dbSNP
rs1345041216 1036 dbSNP
rs949702513 1049 dbSNP
rs1285480608 1056 dbSNP
rs981509446 1063 dbSNP
rs991211308 1063 dbSNP
rs971469824 1069 dbSNP
rs1427388225 1071 dbSNP
rs916033082 1075 dbSNP
rs1208050123 1082 dbSNP
rs1267552047 1084 dbSNP
rs1480506850 1086 dbSNP
rs1200987794 1088 dbSNP
rs188469077 1090 dbSNP
rs1418156150 1095 dbSNP
rs962896511 1099 dbSNP
rs1158765831 1106 dbSNP
rs570737060 1107 dbSNP
rs1017164023 1111 dbSNP
rs539475351 1117 dbSNP
rs530907909 1122 dbSNP
rs1029737416 1128 dbSNP
rs1365008638 1131 dbSNP
rs997893398 1135 dbSNP
rs547687109 1147 dbSNP
rs550874921 1155 dbSNP
rs1348785085 1158 dbSNP
rs1223440836 1160 dbSNP
rs1445269887 1162 dbSNP
rs1318572842 1173 dbSNP
rs1039449997 1174 dbSNP
rs1010670789 1176 dbSNP
rs1490502488 1178 dbSNP
rs1223989550 1186 dbSNP
rs14307 1189 dbSNP
rs952361328 1191 dbSNP
rs1052328048 1193 dbSNP
rs972288973 1196 dbSNP
rs1385111366 1197 dbSNP
rs966049225 1197 dbSNP
rs935248362 1207 dbSNP
rs1018924033 1208 dbSNP
rs1007646040 1213 dbSNP
rs1299000438 1216 dbSNP
rs927942834 1219 dbSNP
rs1046137821 1229 dbSNP
rs568258501 1233 dbSNP
rs1314114934 1239 dbSNP
rs773426020 1246 dbSNP
rs1429227788 1247 dbSNP
rs546433322 1247 dbSNP
rs1306459465 1255 dbSNP
rs1204755201 1257 dbSNP
rs903122810 1264 dbSNP
rs1234202725 1266 dbSNP
rs1482087013 1273 dbSNP
rs1041635141 1278 dbSNP
rs1385530359 1297 dbSNP
rs1242931781 1300 dbSNP
rs1445749827 1301 dbSNP
rs1014097400 1303 dbSNP
rs1337976622 1306 dbSNP
rs373217453 1307 dbSNP
rs564272795 1315 dbSNP
rs1356431036 1317 dbSNP
rs1450743973 1321 dbSNP
rs41267329 1323 dbSNP
rs1404039511 1325 dbSNP
rs1055347047 1330 dbSNP
rs941482903 1335 dbSNP
rs368969960 1343 dbSNP
rs1295385035 1344 dbSNP
rs1172764936 1349 dbSNP
rs1214601240 1350 dbSNP
rs754817820 1354 dbSNP
rs937144974 1363 dbSNP
rs910051511 1365 dbSNP
rs1202706068 1366 dbSNP
rs1049255074 1371 dbSNP
rs1410792037 1372 dbSNP
rs1462075735 1375 dbSNP
rs1419949329 1376 dbSNP
rs930826727 1377 dbSNP
rs1475376456 1382 dbSNP
rs183461333 1386 dbSNP
rs879241377 1389 dbSNP
rs563794333 1404 dbSNP
rs951707183 1409 dbSNP
rs147167703 1415 dbSNP
rs1176025963 1425 dbSNP
rs1406509915 1426 dbSNP
rs1470803217 1433 dbSNP
rs966245353 1436 dbSNP
rs1344469619 1438 dbSNP
rs1431413707 1446 dbSNP
rs1271420753 1448 dbSNP
rs911935403 1450 dbSNP
rs976367815 1451 dbSNP
rs1283584022 1454 dbSNP
rs116023492 1455 dbSNP
rs143378585 1456 dbSNP
rs1033492644 1458 dbSNP
rs1235291812 1460 dbSNP
rs1217211791 1462 dbSNP
rs541686662 1464 dbSNP
rs1010618600 1470 dbSNP
rs115386906 1472 dbSNP
rs1479524026 1473 dbSNP
rs967197178 1484 dbSNP
rs1430192859 1489 dbSNP
rs1481546867 1493 dbSNP
rs1156536455 1500 dbSNP
rs1020040096 1513 dbSNP
rs1401215929 1514 dbSNP
rs1206163089 1519 dbSNP
rs1307777838 1532 dbSNP
rs893600553 1533 dbSNP
rs1031250103 1534 dbSNP
rs1213117571 1535 dbSNP
rs1362069913 1536 dbSNP
rs557916483 1540 dbSNP
rs539037044 1544 dbSNP
rs1055498435 1547 dbSNP
rs552536562 1551 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-1
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796037. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agggAGUGUGUCUUAAGGUCuu 5'
              ||| :|  | ||||||  
Target 5' ----UCAAGCCAAUUUCCAG-- 3'
 		1 - 16
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796037
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-1 / 4-Thiouridine
Location of target site ENST00000358011.4 | 3UTR | UCAAGCCAAUUUCCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells -0.347 5.2e-2 -0.613 9.4e-4 23 Click to see details
GSE28544 Breast cancer -0.264 1.1e-1 -0.291 8.4e-2 24 Click to see details
GSE38226 Liver fibrosis 0.275 1.1e-1 0.345 6.3e-2 21 Click to see details
GSE28260 Renal cortex and medulla 0.26 2.0e-1 0.390 9.4e-2 13 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.085 3.4e-1 -0.053 4.0e-1 25 Click to see details
GSE32688 Pancreatic cancer 0.054 3.8e-1 0.126 2.5e-1 32 Click to see details
GSE26953 Aortic valvular endothelial cells -0.026 4.5e-1 -0.021 4.6e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
75 hsa-miR-1299 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT079552 VAMP3 vesicle associated membrane protein 3 2 2
MIRT154885 GNAS GNAS complex locus 2 4
MIRT275056 SESN2 sestrin 2 2 4
MIRT303051 B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2 4
MIRT319158 CCDC71L coiled-coil domain containing 71 like 2 2
MIRT339620 TMPO thymopoietin 2 2
MIRT441961 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT445113 DCAF4 DDB1 and CUL4 associated factor 4 2 2
MIRT445290 CD274 CD274 molecule 2 2
MIRT446037 HMCN1 hemicentin 1 2 2
MIRT446162 C8A complement C8 alpha chain 2 2
MIRT446175 ZNF37A zinc finger protein 37A 2 4
MIRT446414 OCA2 OCA2 melanosomal transmembrane protein 2 2
MIRT446884 TRIM25 tripartite motif containing 25 2 2
MIRT449789 C1orf109 chromosome 1 open reading frame 109 2 2
MIRT450026 EHD3 EH domain containing 3 2 2
MIRT450367 ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 2 2
MIRT479739 CCND1 cyclin D1 2 2
MIRT484809 ZNFX1 zinc finger NFX1-type containing 1 2 2
MIRT485892 ZFP36 ZFP36 ring finger protein 2 2
MIRT486036 UBBP4 ubiquitin B pseudogene 4 2 2
MIRT488295 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT497377 METTL8 methyltransferase like 8 2 2
MIRT508219 ZNF850 zinc finger protein 850 2 6
MIRT510923 PRRX1 paired related homeobox 1 2 4
MIRT512661 STEAP3 STEAP3 metalloreductase 2 2
MIRT520031 YOD1 YOD1 deubiquitinase 2 6
MIRT528490 AGTR2 angiotensin II receptor type 2 2 2
MIRT530083 PAGR1 PAXIP1 associated glutamate rich protein 1 2 4
MIRT531086 CCDC140 coiled-coil domain containing 140 2 2
MIRT535363 PEX5L peroxisomal biogenesis factor 5 like 2 2
MIRT535595 NUDT21 nudix hydrolase 21 2 2
MIRT538613 CCT5 chaperonin containing TCP1 subunit 5 2 4
MIRT539002 AVL9 AVL9 cell migration associated 2 2
MIRT545918 ZC3H4 zinc finger CCCH-type containing 4 2 2
MIRT548482 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT555088 PURB purine rich element binding protein B 2 2
MIRT561421 TRIB3 tribbles pseudokinase 3 2 2
MIRT564965 WTAP WT1 associated protein 2 2
MIRT571686 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT574656 KLHL15 kelch like family member 15 2 2
MIRT610037 CNOT6 CCR4-NOT transcription complex subunit 6 2 6
MIRT612436 SMOC2 SPARC related modular calcium binding 2 2 2
MIRT614349 LOH12CR1 BLOC-1 related complex subunit 5 2 2
MIRT615304 CCDC158 coiled-coil domain containing 158 2 2
MIRT615771 FSD2 fibronectin type III and SPRY domain containing 2 2 2
MIRT615889 MT1A metallothionein 1A 2 2
MIRT619147 ZNF326 zinc finger protein 326 2 2
MIRT622042 SSBP2 single stranded DNA binding protein 2 2 2
MIRT637385 R3HDM2 R3H domain containing 2 2 2
MIRT640739 EPB41 erythrocyte membrane protein band 4.1 2 2
MIRT644418 PIGS phosphatidylinositol glycan anchor biosynthesis class S 2 2
MIRT647638 FAIM2 Fas apoptotic inhibitory molecule 2 2 2
MIRT654305 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT654367 RBM23 RNA binding motif protein 23 2 2
MIRT655944 NDST1 N-deacetylase and N-sulfotransferase 1 2 2
MIRT655990 MYRF myelin regulatory factor 2 2
MIRT659692 CD226 CD226 molecule 2 2
MIRT665868 TIAF1 TGFB1-induced anti-apoptotic factor 1 2 2
MIRT667317 MYO18A myosin XVIIIA 2 2
MIRT684312 GTF3C4 general transcription factor IIIC subunit 4 2 2
MIRT694138 CYP27C1 cytochrome P450 family 27 subfamily C member 1 2 2
MIRT698529 TFRC transferrin receptor 2 2
MIRT698834 SSR2 signal sequence receptor subunit 2 2 2
MIRT700657 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT705377 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 2 2
MIRT707314 TMEM184B transmembrane protein 184B 2 2
MIRT709027 KBTBD13 kelch repeat and BTB domain containing 13 2 2
MIRT716032 TMPRSS4 transmembrane protease, serine 4 2 2
MIRT718228 LCE1A late cornified envelope 1A 2 2
MIRT718475 TMEM151A transmembrane protein 151A 2 2
MIRT722333 BEND6 BEN domain containing 6 2 2
MIRT734096 TUG1 taurine up-regulated 1 (non-protein coding) 3 0
MIRT734099 NOTCH3 notch 3 3 0
MIRT755871 LIF LIF, interleukin 6 family cytokine 4 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1299 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-1299 Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-1299 Doxorubicin 31703 NSC123127 approved resistant High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-1299 Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-miR-1299 Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-1299 Bromocriptine 31101 NSC169774 approved resistant Low Prolactinoma tissue
hsa-miR-1299 Bromocriptine 31101 NSC169774 approved resistant High Prolactinoma tissue
hsa-miR-1299 Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-1299 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-1299 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1299 Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-1299 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-1299 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-1299 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-miR-1299 Ethanol+Tamoxifen resistant cell line (LY2)
hsa-miR-1299 Pegylated interferon alpha+Ribavirin resistant tissue (chronic hepatitis C)
hsa-miR-1299 Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-1299 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1299 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide sensitive cell line (Bads-200)

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