miRTarBase - #MIRT451362


—
pre-miRNA Information
pre-miRNA hsa-mir-3653   
Genomic Coordinates chr22: 29333158 - 29333267
Description Homo sapiens miR-3653 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3653-5p
Sequence 23| CCUCCUGAUGAUUCUUCUUC |42
Evidence Not_experimental
Experiments
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol UQCR11   
Synonyms 0710008D09Rik, QCR10, UQCR
Description ubiquinol-cytochrome c reductase, complex III subunit XI
Transcript NM_006830   
Expression
Putative miRNA Targets on UQCR11
3'UTR of UQCR11
(miRNA target sites are highlighted)		 
>UQCR11|NM_006830|3'UTR
   1 TTACACAAACCCTTCACAGACTGCTCTGGTGCCTGGTGGTGCTAGCTCCTCCCACCTCAGCACCTGCTGCATCTGGAGCA
  81 GCCCAAGCCTCAGGATGGACAAGAGGAAACCCACAGCTCAGCTTCAGGCTTCTTATGTTTCTGAAAACAGCTTGGATATT
 161 TTAATGCACGTTGCATTAAACCTCACTGAAACCTGCTCCGTGCCCGGATGTTGATCATGCTGGTGGCTTGGTTACTGTGA
 241 CTGTAGCTGGAGTGGCACAGGTGACCCAGGCGTCCTTTCAGCTCCAGAATGTTGCAAGTCTAGGAGAGTGTTCCAATGGC
 321 TGACAGAAACTGCCTATTTGAAATGGCTCATAAGTAGTATCTGCAGTGTGTTCATCCGTTGCTGCCTTAACAAGTCACCC
 401 ACACGTAGTGGCTTAAAGCAACGAACATTCACTCTCTCACAGTCTGTGTCAGTCGGGGATTTGGGAGTGATGTATCTGGG
 481 TGGTTGTGGCCCAGAGTCTCTCATGAGGTTGCAGTTAAGACATCAGCCAAGGCCACTTCGTCTGAGGAAGGCTCAACTGG
 561 GGCTGGAGCCACTTCCAAGCCAGTGCCCTCACGTGGCTGTCGGTGACAGCCACAGTTCCTTCCCATGGGGGCCCCTACAC
 641 GAAGCTGCTTGAGCATCCTCACGGCATGGCCTCTGCCTTCCCCAGAGCAGGTGAACCAAGGGAGAGGAAGGAGCAAGCCA
 721 CAGTGCTTCTATGAGCCACCCTGAGAAGTCTCACGTGATCACTTCCGCCACAGCCTGTTTATCAAAAGCAAGCCCCCCAG
 801 GCCCAGCCCACGTGCAGAGGGAGGAGAATGAGGTTCTGTGTTTTGAAGGGAAGAATATCAGAATTGGTAGACATTTCAAA
 881 CTGTCACATTAGGGATACAAAAATGAACAGGCTGGGAGTGGTGGCTCAGCCTACAATCCCAACACTTTGGGAGGCTGAGG
 961 AAGGGGCATCACTTGAACCAGGAGTTCAGTACTAACCTGGGCAACAAAGAGGCCCCTGTCTCTGATAAAAAGAAAAAAAA
1041 TGAAAAAATAAAAATGAACAGGTATAAAAAGAGAATATGGTACAAAGTC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuUCUUC---UUAGUAGUCCUcc 5'
            || ||   || | ||||||  
Target 5' ggAGCAGCCCAAGCCTCAGGAtg 3'
 75 - 97 134.00 -10.50
2 
miRNA  3' cuUCUUCUUAG------UAGUCCUCc 5'
            ||::| |||      | |||||| 
Target 5' gaAGGGGCATCACTTGAACCAGGAGt 3'
 960 - 985 124.00 -14.80
3 
miRNA  3' cuucuUCUUAG-UAGUCCUCc 5'
               |||:||  ||| ||| 
Target 5' ggcccAGAGTCTCTCATGAGg 3'
 488 - 508 123.00 -13.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN8407630 15 COSMIC
COSN27004251 17 COSMIC
COSN23015349 26 COSMIC
COSN8407629 26 COSMIC
COSN20060487 82 COSMIC
COSN5849629 96 COSMIC
COSN27739840 260 COSMIC
COSN23049731 521 COSMIC
COSN31932593 614 COSMIC
COSN31932006 879 COSMIC
COSN31961475 2007 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs777835261 4 dbSNP
rs772400257 6 dbSNP
rs746145616 8 dbSNP
rs779128283 9 dbSNP
rs1202944899 11 dbSNP
rs757292597 15 dbSNP
rs1376264479 20 dbSNP
rs753875056 23 dbSNP
rs1468640103 28 dbSNP
rs113965864 31 dbSNP
rs1453876689 33 dbSNP
rs1196134007 37 dbSNP
rs540088440 39 dbSNP
rs547174800 47 dbSNP
rs759175910 48 dbSNP
rs1427741809 51 dbSNP
rs961686534 57 dbSNP
rs1055096558 69 dbSNP
rs1014577871 70 dbSNP
rs758930668 71 dbSNP
rs984494334 72 dbSNP
rs1369710042 73 dbSNP
rs1233641330 78 dbSNP
rs951821158 81 dbSNP
rs925838138 82 dbSNP
rs528651223 87 dbSNP
rs1308478117 96 dbSNP
rs1012429579 98 dbSNP
rs945931232 105 dbSNP
rs913050208 111 dbSNP
rs896697243 112 dbSNP
rs987279753 113 dbSNP
rs372933694 116 dbSNP
rs1000223771 117 dbSNP
rs1420055458 121 dbSNP
rs921608083 127 dbSNP
rs1162510424 128 dbSNP
rs974353728 133 dbSNP
rs1461609398 136 dbSNP
rs1327388106 137 dbSNP
rs1371994730 140 dbSNP
rs549303952 150 dbSNP
rs963618420 154 dbSNP
rs1363201064 156 dbSNP
rs1216751517 164 dbSNP
rs771984840 165 dbSNP
rs1010973288 166 dbSNP
rs1234109957 167 dbSNP
rs369562963 168 dbSNP
rs531090283 170 dbSNP
rs1050652379 174 dbSNP
rs188730993 176 dbSNP
rs112914837 177 dbSNP
rs1484188087 179 dbSNP
rs1486802764 180 dbSNP
rs1185577768 183 dbSNP
rs780344009 190 dbSNP
rs1040284312 191 dbSNP
rs950948219 197 dbSNP
rs759537921 198 dbSNP
rs1346378996 204 dbSNP
rs907531719 213 dbSNP
rs984438816 214 dbSNP
rs1355254350 215 dbSNP
rs1055147029 216 dbSNP
rs575840704 218 dbSNP
rs1220832482 219 dbSNP
rs1371049428 224 dbSNP
rs1000890668 227 dbSNP
rs1223353696 234 dbSNP
rs774099972 238 dbSNP
rs916340139 241 dbSNP
rs1043026974 245 dbSNP
rs1256668424 253 dbSNP
rs945949859 254 dbSNP
rs1189732316 257 dbSNP
rs1230880896 259 dbSNP
rs557684936 270 dbSNP
rs1158685471 276 dbSNP
rs1310631194 280 dbSNP
rs1433579362 286 dbSNP
rs544959435 290 dbSNP
rs1409506887 298 dbSNP
rs1432275637 304 dbSNP
rs1172354905 313 dbSNP
rs1359186670 314 dbSNP
rs1178910711 315 dbSNP
rs991356488 316 dbSNP
rs578050605 320 dbSNP
rs1160456508 328 dbSNP
rs960900821 330 dbSNP
rs1255686750 332 dbSNP
rs1441718449 339 dbSNP
rs933099799 342 dbSNP
rs760762611 343 dbSNP
rs1035629125 352 dbSNP
rs1232092392 357 dbSNP
rs1375656875 357 dbSNP
rs559556929 358 dbSNP
rs966974076 359 dbSNP
rs974447212 360 dbSNP
rs1270587300 377 dbSNP
rs1022278120 378 dbSNP
rs1182110687 380 dbSNP
rs1213700825 388 dbSNP
rs1315113342 389 dbSNP
rs1192446380 393 dbSNP
rs758741721 396 dbSNP
rs1395078673 397 dbSNP
rs941729665 403 dbSNP
rs1174725243 404 dbSNP
rs112964628 411 dbSNP
rs1010922344 412 dbSNP
rs889831232 418 dbSNP
rs1438875319 422 dbSNP
rs1302762489 423 dbSNP
rs1371691964 427 dbSNP
rs1236380697 429 dbSNP
rs1268299761 430 dbSNP
rs1049834076 435 dbSNP
rs147968212 437 dbSNP
rs950993523 438 dbSNP
rs552781367 440 dbSNP
rs1025154419 444 dbSNP
rs992712181 450 dbSNP
rs959508499 451 dbSNP
rs901664396 458 dbSNP
rs1201684290 463 dbSNP
rs1413744979 464 dbSNP
rs1379404017 466 dbSNP
rs1304129149 467 dbSNP
rs1040635579 471 dbSNP
rs1033791509 475 dbSNP
rs1428025771 481 dbSNP
rs1345118714 487 dbSNP
rs114311715 490 dbSNP
rs907809327 491 dbSNP
rs772880493 495 dbSNP
rs903893009 497 dbSNP
rs535460893 501 dbSNP
rs1388522021 503 dbSNP
rs1316166898 509 dbSNP
rs1325732126 510 dbSNP
rs769332038 513 dbSNP
rs146763039 515 dbSNP
rs1051625276 516 dbSNP
rs1232318457 520 dbSNP
rs780904610 521 dbSNP
rs1469444589 524 dbSNP
rs1202804392 529 dbSNP
rs1260322321 531 dbSNP
rs933180279 533 dbSNP
rs554728088 537 dbSNP
rs990575118 538 dbSNP
rs1038794536 545 dbSNP
rs941782385 560 dbSNP
rs1459527190 570 dbSNP
rs1485547890 570 dbSNP
rs1156866683 582 dbSNP
rs1247362881 588 dbSNP
rs908885867 593 dbSNP
rs983488133 595 dbSNP
rs1353337704 597 dbSNP
rs1209229113 599 dbSNP
rs1466113047 605 dbSNP
rs1271081875 606 dbSNP
rs183594697 607 dbSNP
rs747570669 608 dbSNP
rs960765866 609 dbSNP
rs1212305757 621 dbSNP
rs928133977 625 dbSNP
rs1033843648 626 dbSNP
rs1321842011 628 dbSNP
rs1187616246 629 dbSNP
rs191422749 630 dbSNP
rs1425781711 633 dbSNP
rs966920118 635 dbSNP
rs557005836 638 dbSNP
rs1022559974 639 dbSNP
rs968088622 641 dbSNP
rs1373500334 642 dbSNP
rs780451373 643 dbSNP
rs1433921741 646 dbSNP
rs1020965073 652 dbSNP
rs1380973620 664 dbSNP
rs1458728242 665 dbSNP
rs1351843173 667 dbSNP
rs1009962765 668 dbSNP
rs891112107 678 dbSNP
rs1011205371 679 dbSNP
rs1288806407 682 dbSNP
rs1346310588 685 dbSNP
rs758753758 691 dbSNP
rs900384095 695 dbSNP
rs1484411099 697 dbSNP
rs1451307872 701 dbSNP
rs1028771404 703 dbSNP
rs1251048591 704 dbSNP
rs1419773191 709 dbSNP
rs750758497 712 dbSNP
rs1488651228 716 dbSNP
rs1266864191 717 dbSNP
rs1360696494 725 dbSNP
rs1460218232 729 dbSNP
rs1297281713 731 dbSNP
rs568479081 731 dbSNP
rs1201957841 732 dbSNP
rs901273523 735 dbSNP
rs765442740 736 dbSNP
rs1018703430 743 dbSNP
rs887499901 744 dbSNP
rs1314342383 748 dbSNP
rs1047454091 749 dbSNP
rs1004680570 766 dbSNP
rs1200675957 767 dbSNP
rs762816413 769 dbSNP
rs553469377 772 dbSNP
rs538591862 773 dbSNP
rs1303233692 774 dbSNP
rs369272643 775 dbSNP
rs1169454933 785 dbSNP
rs1373328340 786 dbSNP
rs1466856027 788 dbSNP
rs1323414247 790 dbSNP
rs1393270583 791 dbSNP
rs1393107734 792 dbSNP
rs1440957996 794 dbSNP
rs1294656939 803 dbSNP
rs1296702515 813 dbSNP
rs1370335933 814 dbSNP
rs571342812 815 dbSNP
rs926783521 820 dbSNP
rs1318941931 823 dbSNP
rs1220710452 847 dbSNP
rs1371374424 851 dbSNP
rs1271430796 861 dbSNP
rs1055220835 863 dbSNP
rs142569188 866 dbSNP
rs534701746 868 dbSNP
rs1393208787 869 dbSNP
rs567794161 870 dbSNP
rs1484833426 871 dbSNP
rs978216813 877 dbSNP
rs945524791 882 dbSNP
rs915449211 886 dbSNP
rs1175240761 887 dbSNP
rs1482554843 895 dbSNP
rs1166254888 896 dbSNP
rs1239054713 896 dbSNP
rs1341526863 896 dbSNP
rs1402191129 896 dbSNP
rs869275138 896 dbSNP
rs1274902032 897 dbSNP
rs1334410295 899 dbSNP
rs955593914 901 dbSNP
rs1292103520 904 dbSNP
rs1029661825 912 dbSNP
rs997392015 914 dbSNP
rs760421680 915 dbSNP
rs1345048716 920 dbSNP
rs964565937 922 dbSNP
rs1234558907 924 dbSNP
rs1333307869 931 dbSNP
rs1185505227 932 dbSNP
rs1256418827 937 dbSNP
rs1017404433 939 dbSNP
rs989720617 940 dbSNP
rs1351408960 941 dbSNP
rs1158607584 942 dbSNP
rs1361677273 945 dbSNP
rs954467679 946 dbSNP
rs1311405505 947 dbSNP
rs1355134209 950 dbSNP
rs1028302633 951 dbSNP
rs1371321960 953 dbSNP
rs977169749 957 dbSNP
rs1223248061 959 dbSNP
rs1309953720 961 dbSNP
rs1047968940 962 dbSNP
rs1374884638 964 dbSNP
rs993256710 967 dbSNP
rs1173202426 971 dbSNP
rs753912885 972 dbSNP
rs151166038 979 dbSNP
rs764196554 980 dbSNP
rs759445744 981 dbSNP
rs1379280040 982 dbSNP
rs189245167 991 dbSNP
rs1027473179 992 dbSNP
rs1172222898 996 dbSNP
rs994745072 1001 dbSNP
rs1415366698 1010 dbSNP
rs895072418 1012 dbSNP
rs1183837451 1013 dbSNP
rs1446189812 1022 dbSNP
rs946906488 1029 dbSNP
rs1379101386 1035 dbSNP
rs1232008552 1048 dbSNP
rs1054765645 1052 dbSNP
rs1302504634 1060 dbSNP
rs1345491097 1076 dbSNP
rs1220692190 1078 dbSNP
rs914067306 1082 dbSNP
rs939018591 1083 dbSNP
rs1436831502 1085 dbSNP
rs988672383 1086 dbSNP
rs1254926144 1102 dbSNP
rs1200511377 1105 dbSNP
rs1466702643 1108 dbSNP
rs906237846 1109 dbSNP
rs1192309691 1113 dbSNP
rs1377515345 1121 dbSNP
rs1478591602 1122 dbSNP
rs563590856 1124 dbSNP
rs551381395 1125 dbSNP
rs1228171026 1129 dbSNP
rs533138851 1130 dbSNP
rs535125371 1131 dbSNP
rs1402554516 1137 dbSNP
rs142120628 1138 dbSNP
rs1322837868 1139 dbSNP
rs1331584650 1154 dbSNP
rs1290475148 1157 dbSNP
rs1413211248 1158 dbSNP
rs566629112 1160 dbSNP
rs975356872 1164 dbSNP
rs1259511717 1171 dbSNP
rs774294865 1176 dbSNP
rs1304393586 1181 dbSNP
rs921521940 1187 dbSNP
rs570532303 1190 dbSNP
rs1452690922 1194 dbSNP
rs1006086321 1200 dbSNP
rs541193874 1207 dbSNP
rs965754943 1208 dbSNP
rs574076655 1220 dbSNP
rs184594441 1222 dbSNP
rs112583151 1223 dbSNP
rs761272122 1229 dbSNP
rs8697 1236 dbSNP
rs1391443774 1239 dbSNP
rs1027420698 1244 dbSNP
rs1388428262 1249 dbSNP
rs1316058804 1250 dbSNP
rs896206201 1259 dbSNP
rs3180530 1269 dbSNP
rs1400335819 1271 dbSNP
rs1279754822 1275 dbSNP
rs1353149512 1299 dbSNP
rs995090816 1301 dbSNP
rs1265502047 1307 dbSNP
rs1044278 1309 dbSNP
rs1001895564 1310 dbSNP
rs11552188 1310 dbSNP
rs1212160895 1311 dbSNP
rs959280967 1315 dbSNP
rs3183988 1328 dbSNP
rs1474051686 1332 dbSNP
rs1488180289 1348 dbSNP
rs1194814750 1350 dbSNP
rs1367518306 1351 dbSNP
rs1265666409 1360 dbSNP
rs904849803 1362 dbSNP
rs1034012132 1365 dbSNP
rs1044037307 1366 dbSNP
rs946988169 1373 dbSNP
rs1443577202 1378 dbSNP
rs1156770278 1380 dbSNP
rs1359803962 1383 dbSNP
rs3177161 1392 dbSNP
rs113927061 1393 dbSNP
rs1260279476 1394 dbSNP
rs78569796 1395 dbSNP
rs557267192 1396 dbSNP
rs1395106533 1401 dbSNP
rs1312905674 1402 dbSNP
rs1465717858 1415 dbSNP
rs1236193545 1421 dbSNP
rs906188472 1423 dbSNP
rs1307776951 1433 dbSNP
rs1042101160 1437 dbSNP
rs549354076 1438 dbSNP
rs1009298452 1439 dbSNP
rs1288584201 1441 dbSNP
rs1482445987 1441 dbSNP
rs1200092556 1443 dbSNP
rs893574654 1445 dbSNP
rs577602360 1463 dbSNP
rs1425655122 1464 dbSNP
rs1179716532 1467 dbSNP
rs1053922815 1468 dbSNP
rs1440228596 1468 dbSNP
rs772895677 1475 dbSNP
rs1393041361 1477 dbSNP
rs1465327577 1485 dbSNP
rs1284929182 1492 dbSNP
rs1403873323 1499 dbSNP
rs769555760 1500 dbSNP
rs193113621 1502 dbSNP
rs1247098798 1505 dbSNP
rs1324714176 1511 dbSNP
rs201593782 1511 dbSNP
rs975455253 1513 dbSNP
rs747874579 1514 dbSNP
rs1310838427 1524 dbSNP
rs372527676 1527 dbSNP
rs1232925002 1532 dbSNP
rs909882667 1536 dbSNP
rs768497835 1540 dbSNP
rs944321057 1543 dbSNP
rs534468345 1549 dbSNP
rs1458217820 1556 dbSNP
rs982763794 1560 dbSNP
rs1180466374 1567 dbSNP
rs1393142367 1568 dbSNP
rs1432434118 1573 dbSNP
rs116989251 1574 dbSNP
rs971896243 1578 dbSNP
rs1460139941 1581 dbSNP
rs1169443463 1586 dbSNP
rs1400391896 1589 dbSNP
rs1448294025 1590 dbSNP
rs960802348 1592 dbSNP
rs555541358 1593 dbSNP
rs1280267854 1600 dbSNP
rs537216943 1601 dbSNP
rs1314255453 1607 dbSNP
rs959459803 1609 dbSNP
rs1034798310 1612 dbSNP
rs764935647 1613 dbSNP
rs1033547797 1618 dbSNP
rs1003854268 1619 dbSNP
rs1488113408 1632 dbSNP
rs1191616571 1635 dbSNP
rs1269217247 1635 dbSNP
rs768233495 1635 dbSNP
rs1192517416 1637 dbSNP
rs1423830355 1642 dbSNP
rs1466774561 1644 dbSNP
rs570028403 1650 dbSNP
rs1021931482 1654 dbSNP
rs1457857765 1659 dbSNP
rs1011584148 1667 dbSNP
rs370070622 1670 dbSNP
rs892690944 1671 dbSNP
rs1398488787 1673 dbSNP
rs1277859169 1674 dbSNP
rs1370882193 1675 dbSNP
rs1341329512 1676 dbSNP
rs1220615157 1678 dbSNP
rs1053052402 1690 dbSNP
rs934204022 1691 dbSNP
rs1020605939 1699 dbSNP
rs188497474 1715 dbSNP
rs1412877912 1718 dbSNP
rs1212212044 1723 dbSNP
rs1487196593 1725 dbSNP
rs1009246088 1728 dbSNP
rs1290884774 1731 dbSNP
rs746550415 1735 dbSNP
rs893519496 1736 dbSNP
rs1179696243 1753 dbSNP
rs1412453633 1757 dbSNP
rs1053942550 1760 dbSNP
rs1166138973 1762 dbSNP
rs551689841 1765 dbSNP
rs1418300001 1771 dbSNP
rs942748268 1778 dbSNP
rs533653722 1779 dbSNP
rs565985246 1780 dbSNP
rs984108185 1782 dbSNP
rs1365925499 1783 dbSNP
rs547761077 1788 dbSNP
rs1314825716 1789 dbSNP
rs1351374562 1790 dbSNP
rs1215703805 1797 dbSNP
rs529377572 1798 dbSNP
rs1489112924 1799 dbSNP
rs1207631129 1800 dbSNP
rs183440807 1803 dbSNP
rs542865821 1806 dbSNP
rs1034850519 1809 dbSNP
rs931312940 1810 dbSNP
rs1323931007 1814 dbSNP
rs1387707624 1814 dbSNP
rs919973895 1818 dbSNP
rs991970561 1820 dbSNP
rs1402762358 1821 dbSNP
rs1332458681 1826 dbSNP
rs980521237 1834 dbSNP
rs969093629 1836 dbSNP
rs1021983864 1837 dbSNP
rs958844431 1841 dbSNP
rs530691610 1843 dbSNP
rs1239347263 1844 dbSNP
rs1010548927 1846 dbSNP
rs1429750335 1849 dbSNP
rs1392577318 1858 dbSNP
rs892107710 1859 dbSNP
rs1031285322 1867 dbSNP
rs1442640093 1871 dbSNP
rs569032384 1874 dbSNP
rs758846382 1877 dbSNP
rs867854153 1878 dbSNP
rs1235843274 1886 dbSNP
rs1456880883 1896 dbSNP
rs1178602049 1898 dbSNP
rs1201438425 1899 dbSNP
rs1471387259 1901 dbSNP
rs1436351723 1925 dbSNP
rs1424804616 1931 dbSNP
rs926428615 1935 dbSNP
rs901351123 1939 dbSNP
rs1205964082 1947 dbSNP
rs192901483 1950 dbSNP
rs970600545 1951 dbSNP
rs545005363 1962 dbSNP
rs988094408 1969 dbSNP
rs1337431913 1973 dbSNP
rs1434116022 1976 dbSNP
rs1274016833 1985 dbSNP
rs957682120 1989 dbSNP
rs1220602683 1996 dbSNP
rs1048937239 2002 dbSNP
rs1032034041 2007 dbSNP
rs187313054 2008 dbSNP
rs1275281540 2009 dbSNP
rs1259311549 2012 dbSNP
rs899599472 2015 dbSNP
rs1036323452 2021 dbSNP
rs1020170930 2023 dbSNP
rs1478539948 2025 dbSNP
rs1201894939 2028 dbSNP
rs1008357318 2034 dbSNP
rs1421733118 2040 dbSNP
rs376013297 2041 dbSNP
rs927792314 2046 dbSNP
rs1047295422 2051 dbSNP
rs1409924118 2053 dbSNP
rs1371822668 2054 dbSNP
rs1322736076 2055 dbSNP
rs980573317 2057 dbSNP
rs1414452452 2066 dbSNP
rs1406491244 2077 dbSNP
rs540972239 2079 dbSNP
rs1275960063 2081 dbSNP
rs573421110 2084 dbSNP
rs1339406483 2090 dbSNP
rs757442467 2094 dbSNP
rs555009178 2098 dbSNP
rs915020660 2104 dbSNP
rs1208615923 2105 dbSNP
rs754106144 2106 dbSNP
rs764319226 2107 dbSNP
rs536731707 2111 dbSNP
rs372379707 2114 dbSNP
rs148603790 2115 dbSNP
rs1344720012 2121 dbSNP
rs1261386493 2125 dbSNP
rs1031044061 2127 dbSNP
rs1194588516 2130 dbSNP
rs12611285 2137 dbSNP
rs1055820703 2144 dbSNP
rs1471826726 2145 dbSNP
rs1162608815 2159 dbSNP
rs937396765 2162 dbSNP
rs1018414932 2183 dbSNP
rs928745448 2188 dbSNP
rs781457763 2197 dbSNP
rs1484096460 2199 dbSNP
rs1296110572 2206 dbSNP
rs1359567096 2208 dbSNP
rs1007033409 2213 dbSNP
rs981903271 2215 dbSNP
rs1338216382 2216 dbSNP
rs888599890 2223 dbSNP
rs1062810 2228 dbSNP
rs1048508424 2230 dbSNP
rs1279152059 2237 dbSNP
rs994660108 2237 dbSNP
rs1220751271 2248 dbSNP
rs1326755606 2249 dbSNP
rs1217658944 2256 dbSNP
rs949195830 2258 dbSNP
rs539785926 2260 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cuucuucuuaguaGUCCUCc 5'
                       |||||| 
Target 5' -------cugaggCAGGAGa 3'
 		1 - 13
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000589880.1 | 3UTR | CUGAGGCAGGAGAAUUACUUGAACCCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
543 hsa-miR-3653-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT118037 SLC1A5 solute carrier family 1 member 5 2 2
MIRT134378 E2F2 E2F transcription factor 2 2 2
MIRT171365 PHTF2 putative homeodomain transcription factor 2 2 2
MIRT174716 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT250468 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 2 2
MIRT261002 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 2 4
MIRT306045 SKIL SKI like proto-oncogene 2 4
MIRT352741 CSNK1E casein kinase 1 epsilon 2 2
MIRT380445 SLC2A1 solute carrier family 2 member 1 2 2
MIRT442181 SRP68 signal recognition particle 68 2 6
MIRT448534 RIMS4 regulating synaptic membrane exocytosis 4 2 2
MIRT451362 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451444 ZNF556 zinc finger protein 556 2 4
MIRT452667 PPIA peptidylprolyl isomerase A 2 2
MIRT458768 CES2 carboxylesterase 2 2 2
MIRT460268 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460535 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT460602 FEM1A fem-1 homolog A 2 4
MIRT463622 YY1 YY1 transcription factor 2 2
MIRT473708 MAPK1 mitogen-activated protein kinase 1 2 6
MIRT474922 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT478532 CTNS cystinosin, lysosomal cystine transporter 2 2
MIRT482760 TMEM126B transmembrane protein 126B 2 2
MIRT491029 FDX1 ferredoxin 1 2 4
MIRT492753 PER1 period circadian clock 1 2 8
MIRT494140 CTC1 CST telomere replication complex component 1 2 10
MIRT497863 UBA5 ubiquitin like modifier activating enzyme 5 2 4
MIRT512405 CD84 CD84 molecule 2 2
MIRT512529 ATCAY ATCAY, caytaxin 2 4
MIRT513039 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT517888 SSTR2 somatostatin receptor 2 2 2
MIRT520420 TXNL1 thioredoxin like 1 2 6
MIRT521826 POLR1D RNA polymerase I subunit D 2 2
MIRT534072 SRPK1 SRSF protein kinase 1 2 2
MIRT534240 SLC23A1 solute carrier family 23 member 1 2 2
MIRT538794 C3orf52 chromosome 3 open reading frame 52 2 2
MIRT538980 BCL2L2 BCL2 like 2 2 2
MIRT542111 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 4
MIRT546462 SLC39A14 solute carrier family 39 member 14 2 2
MIRT552217 SSPN sarcospan 2 2
MIRT552224 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 2 2
MIRT554420 SATB2 SATB homeobox 2 2 2
MIRT555385 PPP1CC protein phosphatase 1 catalytic subunit gamma 2 2
MIRT569625 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT573895 MKI67 marker of proliferation Ki-67 2 2
MIRT575161 Fam120c family with sequence similarity 120, member C 2 2
MIRT607347 YAE1D1 Yae1 domain containing 1 2 6
MIRT607413 MCTS1 MCTS1, re-initiation and release factor 2 2
MIRT608320 SYK spleen associated tyrosine kinase 2 4
MIRT608473 RRP36 ribosomal RNA processing 36 2 2
MIRT608523 TMOD3 tropomodulin 3 2 4
MIRT608572 RNF149 ring finger protein 149 2 2
MIRT608609 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT608676 STPG1 sperm tail PG-rich repeat containing 1 2 2
MIRT608724 ZKSCAN1 zinc finger with KRAB and SCAN domains 1 2 2
MIRT610392 FOXE1 forkhead box E1 2 2
MIRT610537 FAM46A family with sequence similarity 46 member A 2 4
MIRT610664 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT611258 EHD3 EH domain containing 3 2 2
MIRT612247 MICALL1 MICAL like 1 2 2
MIRT613500 ZNF488 zinc finger protein 488 2 2
MIRT613790 RPS6 ribosomal protein S6 2 2
MIRT613832 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT614357 LOH12CR1 BLOC-1 related complex subunit 5 2 2
MIRT614539 NOA1 nitric oxide associated 1 2 2
MIRT615947 SORD sorbitol dehydrogenase 2 2
MIRT616144 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT617103 MPPE1 metallophosphoesterase 1 2 2
MIRT617383 FAM227A family with sequence similarity 227 member A 2 2
MIRT618126 LACTB lactamase beta 2 4
MIRT618236 PGBD4 piggyBac transposable element derived 4 2 2
MIRT618262 DDX51 DEAD-box helicase 51 2 2
MIRT618286 ZNF682 zinc finger protein 682 2 4
MIRT618316 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT618678 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT619206 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT619658 CORO2A coronin 2A 2 2
MIRT619726 FPR2 formyl peptide receptor 2 2 2
MIRT619870 ZNF347 zinc finger protein 347 2 2
MIRT620129 ZNF283 zinc finger protein 283 2 2
MIRT621087 WDR12 WD repeat domain 12 2 2
MIRT621114 SP110 SP110 nuclear body protein 2 2
MIRT621129 EMC7 ER membrane protein complex subunit 7 2 4
MIRT621236 SIGLEC9 sialic acid binding Ig like lectin 9 2 4
MIRT621421 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT621576 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT621689 TSPYL1 TSPY like 1 2 2
MIRT621794 TMEM233 transmembrane protein 233 2 2
MIRT621929 SYAP1 synapse associated protein 1 2 4
MIRT621965 STRIP2 striatin interacting protein 2 2 2
MIRT622102 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT622184 SLC7A14 solute carrier family 7 member 14 2 2
MIRT622238 SLC25A45 solute carrier family 25 member 45 2 2
MIRT622473 RNF11 ring finger protein 11 2 2
MIRT622514 RBM20 RNA binding motif protein 20 2 2
MIRT622523 RAD51 RAD51 recombinase 2 2
MIRT622665 POLQ DNA polymerase theta 2 4
MIRT622699 PLEKHO1 pleckstrin homology domain containing O1 2 2
MIRT622831 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT622873 PDE12 phosphodiesterase 12 2 2
MIRT623031 OCIAD2 OCIA domain containing 2 2 2
MIRT623083 NME6 NME/NM23 nucleoside diphosphate kinase 6 2 2
MIRT623303 MARCH7 membrane associated ring-CH-type finger 7 2 2
MIRT623932 FKBP14 FK506 binding protein 14 2 2
MIRT624060 EIF4E eukaryotic translation initiation factor 4E 2 2
MIRT624295 COMMD2 COMM domain containing 2 2 2
MIRT624521 C3orf62 chromosome 3 open reading frame 62 2 2
MIRT624824 ACO1 aconitase 1 2 2
MIRT624908 CTCFL CCCTC-binding factor like 2 2
MIRT625154 ZCCHC8 zinc finger CCHC-type containing 8 2 4
MIRT625382 ZNF716 zinc finger protein 716 2 2
MIRT625771 RBM3 RNA binding motif (RNP1, RRM) protein 3 2 4
MIRT625808 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT625835 NXPE2 neurexophilin and PC-esterase domain family member 2 2 2
MIRT626010 ZNF517 zinc finger protein 517 2 2
MIRT626058 AP3M1 adaptor related protein complex 3 mu 1 subunit 2 2
MIRT626116 IL23R interleukin 23 receptor 2 2
MIRT626252 RBM43 RNA binding motif protein 43 2 2
MIRT626350 PACS1 phosphofurin acidic cluster sorting protein 1 2 2
MIRT626888 ANGEL1 angel homolog 1 2 2
MIRT627303 WDR31 WD repeat domain 31 2 2
MIRT627597 SGK494 uncharacterized serine/threonine-protein kinase SgK494 2 2
MIRT627618 SF3B1 splicing factor 3b subunit 1 2 2
MIRT627630 SENP8 SUMO/sentrin peptidase family member, NEDD8 specific 2 2
MIRT627642 SEC23IP SEC23 interacting protein 2 2
MIRT627651 SAR1A secretion associated Ras related GTPase 1A 2 4
MIRT628388 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT628675 C2orf72 chromosome 2 open reading frame 72 2 2
MIRT628780 TMEM154 transmembrane protein 154 2 2
MIRT629181 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT629266 NXPE1 neurexophilin and PC-esterase domain family member 1 2 2
MIRT629307 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT629322 ZNF487P zinc finger protein 487 1 1
MIRT629524 ZNF37A zinc finger protein 37A 2 2
MIRT629611 NOL10 nucleolar protein 10 2 2
MIRT629659 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT629671 USP1 ubiquitin specific peptidase 1 2 2
MIRT629765 STK25 serine/threonine kinase 25 2 2
MIRT630447 IDE insulin degrading enzyme 2 2
MIRT630903 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT631001 ZNF573 zinc finger protein 573 2 2
MIRT631157 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT631178 HCAR1 hydroxycarboxylic acid receptor 1 2 2
MIRT631339 ZNF84 zinc finger protein 84 2 2
MIRT631342 LATS1 large tumor suppressor kinase 1 2 2
MIRT631359 ZFP30 ZFP30 zinc finger protein 2 4
MIRT631461 FBXO47 F-box protein 47 2 2
MIRT631585 ITGAL integrin subunit alpha L 2 2
MIRT631597 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT631643 WDR91 WD repeat domain 91 2 4
MIRT631781 IL17RA interleukin 17 receptor A 2 2
MIRT631858 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT632040 ZNF430 zinc finger protein 430 2 2
MIRT632094 SSR1 signal sequence receptor subunit 1 2 2
MIRT632153 CWC25 CWC25 spliceosome associated protein homolog 2 2
MIRT632234 VTA1 vesicle trafficking 1 2 2
MIRT632287 TTPAL alpha tocopherol transfer protein like 2 2
MIRT632328 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632392 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT632412 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632557 PRPF38A pre-mRNA processing factor 38A 2 2
MIRT633066 DENND5B DENN domain containing 5B 2 2
MIRT633185 AAK1 AP2 associated kinase 1 2 2
MIRT633196 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT633220 ZNF584 zinc finger protein 584 2 2
MIRT633343 GRK4 G protein-coupled receptor kinase 4 2 2
MIRT633407 ZNF566 zinc finger protein 566 2 2
MIRT633479 ZNF724P zinc finger protein 724 2 2
MIRT633485 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 2 2
MIRT633516 LRRC27 leucine rich repeat containing 27 2 2
MIRT633556 DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 2 2
MIRT633659 SLC28A1 solute carrier family 28 member 1 2 2
MIRT633681 ZNF576 zinc finger protein 576 2 2
MIRT633758 CENPBD1 CENPB DNA-binding domain containing 1 2 2
MIRT633771 SWSAP1 SWIM-type zinc finger 7 associated protein 1 2 2
MIRT633776 F2 coagulation factor II, thrombin 2 2
MIRT633803 ZNF91 zinc finger protein 91 2 2
MIRT633813 WDR92 WD repeat domain 92 2 2
MIRT633948 TMEM231 transmembrane protein 231 2 2
MIRT634000 RTN2 reticulon 2 2 2
MIRT634024 MOB4 MOB family member 4, phocein 2 2
MIRT634228 TMEM132B transmembrane protein 132B 2 2
MIRT634320 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634355 RNF157 ring finger protein 157 2 2
MIRT634586 KIAA1958 KIAA1958 2 2
MIRT634748 CRCP CGRP receptor component 2 2
MIRT635409 KIAA1614 KIAA1614 2 2
MIRT635461 GBP4 guanylate binding protein 4 2 2
MIRT635501 CCR4 C-C motif chemokine receptor 4 2 2
MIRT635627 CDT1 chromatin licensing and DNA replication factor 1 2 4
MIRT635646 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT635750 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha 2 2
MIRT635824 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT635969 TTC31 tetratricopeptide repeat domain 31 2 2
MIRT636121 YPEL1 yippee like 1 2 2
MIRT636171 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT636194 TCEB1 elongin C 2 2
MIRT636772 CLUAP1 clusterin associated protein 1 2 2
MIRT636799 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT636955 APTX aprataxin 2 2
MIRT637096 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT637149 PCDHA6 protocadherin alpha 6 2 2
MIRT637207 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT637321 FAM9B family with sequence similarity 9 member B 2 2
MIRT637544 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT637632 ZNF431 zinc finger protein 431 2 2
MIRT637658 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT637704 ZNF439 zinc finger protein 439 2 2
MIRT637807 GGPS1 geranylgeranyl diphosphate synthase 1 2 2
MIRT637831 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT637907 FAM153B family with sequence similarity 153 member B 2 4
MIRT637953 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT637974 IRF1 interferon regulatory factor 1 2 2
MIRT638026 FIG4 FIG4 phosphoinositide 5-phosphatase 2 2
MIRT638066 KCNN1 potassium calcium-activated channel subfamily N member 1 2 2
MIRT638197 TAOK1 TAO kinase 1 2 2
MIRT638403 PRR11 proline rich 11 2 2
MIRT638625 GSR glutathione-disulfide reductase 2 4
MIRT638651 GK5 glycerol kinase 5 (putative) 2 2
MIRT638993 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT639000 ADO 2-aminoethanethiol dioxygenase 2 2
MIRT642200 SMAGP small cell adhesion glycoprotein 2 2
MIRT642537 CERS4 ceramide synthase 4 2 2
MIRT643021 LETM2 leucine zipper and EF-hand containing transmembrane protein 2 2 2
MIRT643423 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT643459 LAX1 lymphocyte transmembrane adaptor 1 2 4
MIRT643766 NAGK N-acetylglucosamine kinase 2 2
MIRT643892 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2 2
MIRT644097 SIAH3 siah E3 ubiquitin protein ligase family member 3 2 2
MIRT644680 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT644710 ZNF321P zinc finger protein 321, pseudogene 2 2
MIRT644726 SEPT14 septin 14 2 2
MIRT645138 HES2 hes family bHLH transcription factor 2 2 2
MIRT645314 AGTRAP angiotensin II receptor associated protein 2 2
MIRT645561 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT645737 POLR3A RNA polymerase III subunit A 2 2
MIRT646042 NPR1 natriuretic peptide receptor 1 2 2
MIRT646150 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT646362 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT646566 ALDH5A1 aldehyde dehydrogenase 5 family member A1 2 2
MIRT646871 NT5C2 5'-nucleotidase, cytosolic II 2 2
MIRT647022 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647104 GNL3L G protein nucleolar 3 like 2 2
MIRT647363 WDR5B WD repeat domain 5B 2 2
MIRT648059 TRMT10C tRNA methyltransferase 10C, mitochondrial RNase P subunit 2 2
MIRT648088 FAM192A family with sequence similarity 192 member A 2 2
MIRT648152 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT648432 MYOZ3 myozenin 3 2 2
MIRT648451 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT648920 ZNF551 zinc finger protein 551 2 2
MIRT649104 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT649109 RPL37 ribosomal protein L37 2 2
MIRT649259 IMPA2 inositol monophosphatase 2 2 2
MIRT649742 GNB5 G protein subunit beta 5 2 2
MIRT650092 TERF2 telomeric repeat binding factor 2 2 2
MIRT650578 TTR transthyretin 2 2
MIRT650739 FKTN fukutin 2 2
MIRT650871 APOH apolipoprotein H 2 2
MIRT651024 ZNF699 zinc finger protein 699 2 2
MIRT651391 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT651526 WNT2B Wnt family member 2B 2 2
MIRT652640 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT653261 SOGA3 SOGA family member 3 2 2
MIRT653285 SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2 2
MIRT653526 SLC38A9 solute carrier family 38 member 9 2 2
MIRT653708 SLC25A33 solute carrier family 25 member 33 2 2
MIRT653826 SHROOM4 shroom family member 4 2 2
MIRT653888 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT654217 RNF19B ring finger protein 19B 2 2
MIRT654848 PPM1K protein phosphatase, Mg2+/Mn2+ dependent 1K 2 2
MIRT655370 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT655520 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT656962 KIAA0408 KIAA0408 2 2
MIRT657048 KCNH6 potassium voltage-gated channel subfamily H member 6 2 2
MIRT657113 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT657198 IKZF3 IKAROS family zinc finger 3 2 2
MIRT657269 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT657317 HOOK3 hook microtubule tethering protein 3 2 2
MIRT657365 HMGB1 high mobility group box 1 2 2
MIRT657522 GTF2H5 general transcription factor IIH subunit 5 2 4
MIRT657535 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT659037 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659590 CEP135 centrosomal protein 135 2 2
MIRT659801 CAV2 caveolin 2 2 2
MIRT659947 C8orf44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT660693 ANAPC1 anaphase promoting complex subunit 1 2 4
MIRT660951 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT660989 ABHD2 abhydrolase domain containing 2 2 2
MIRT661410 GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 2 2
MIRT661524 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661752 ATM ATM serine/threonine kinase 2 2
MIRT662158 ALDH7A1 aldehyde dehydrogenase 7 family member A1 2 2
MIRT663363 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT663513 AGMO alkylglycerol monooxygenase 2 2
MIRT663533 ZNF70 zinc finger protein 70 2 2
MIRT663633 HM13 histocompatibility minor 13 2 2
MIRT663760 ZNF285 zinc finger protein 285 2 2
MIRT663841 TRIM72 tripartite motif containing 72 2 2
MIRT664024 C9orf139 chromosome 9 open reading frame 139 2 2
MIRT664049 ANKRD62 ankyrin repeat domain 62 2 2
MIRT664118 C4orf32 family with sequence similarity 241 member A 2 2
MIRT664280 RNMTL1 mitochondrial rRNA methyltransferase 3 2 2
MIRT664642 GALM galactose mutarotase 2 2
MIRT664685 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT664764 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665281 ZFP14 ZFP14 zinc finger protein 2 2
MIRT665874 TGOLN2 trans-golgi network protein 2 2 2
MIRT666194 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT666416 SH3D19 SH3 domain containing 19 2 2
MIRT666917 POC1A POC1 centriolar protein A 2 2
MIRT666946 PLSCR1 phospholipid scramblase 1 2 2
MIRT667064 PAOX polyamine oxidase 2 2
MIRT667090 OSTF1 osteoclast stimulating factor 1 2 2
MIRT667677 KPNA6 karyopherin subunit alpha 6 2 2
MIRT667790 KARS lysyl-tRNA synthetase 2 2
MIRT668268 FOXO3 forkhead box O3 2 2
MIRT668555 ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit 2 2
MIRT668830 CYCS cytochrome c, somatic 2 2
MIRT669087 CDX2 caudal type homeobox 2 2 2
MIRT669397 BACE2 beta-site APP-cleaving enzyme 2 2 4
MIRT669571 AKIRIN1 akirin 1 2 2
MIRT669761 ZNF101 zinc finger protein 101 2 2
MIRT669802 GAN gigaxonin 2 2
MIRT669811 STOML1 stomatin like 1 2 2
MIRT669869 MELK maternal embryonic leucine zipper kinase 2 2
MIRT669928 LRPAP1 LDL receptor related protein associated protein 1 2 2
MIRT669952 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT670052 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT670100 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT670302 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670391 EMP2 epithelial membrane protein 2 2 2
MIRT670487 DCUN1D2 defective in cullin neddylation 1 domain containing 2 2 2
MIRT670537 KIF1C kinesin family member 1C 2 2
MIRT670608 NPHP1 nephrocystin 1 2 2
MIRT670789 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT670885 CYTIP cytohesin 1 interacting protein 2 2
MIRT670936 LIPG lipase G, endothelial type 2 2
MIRT671267 MTRNR2L5 MT-RNR2-like 5 2 2
MIRT671307 RABGAP1L RAB GTPase activating protein 1 like 2 2
MIRT671518 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 2
MIRT671628 C20orf144 chromosome 20 open reading frame 144 2 4
MIRT671683 ADK adenosine kinase 2 2
MIRT671786 RGS17 regulator of G protein signaling 17 2 2
MIRT671811 WISP3 WNT1 inducible signaling pathway protein 3 2 2
MIRT672006 SLC35F6 solute carrier family 35 member F6 2 4
MIRT672106 TLCD2 TLC domain containing 2 2 2
MIRT672238 ABHD15 abhydrolase domain containing 15 2 2
MIRT672274 SHE Src homology 2 domain containing E 2 2
MIRT672325 C9orf3 chromosome 9 open reading frame 3 2 2
MIRT672696 ZNF677 zinc finger protein 677 2 2
MIRT672817 VEZT vezatin, adherens junctions transmembrane protein 2 2
MIRT672863 C22orf29 retrotransposon Gag like 10 2 2
MIRT672891 FXN frataxin 2 2
MIRT672980 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT673256 INO80 INO80 complex subunit 2 2
MIRT673400 WNT7B Wnt family member 7B 2 2
MIRT673527 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT673544 DEGS1 delta 4-desaturase, sphingolipid 1 2 2
MIRT674004 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT674018 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT674249 NUP62 nucleoporin 62 2 4
MIRT674358 SLC35E3 solute carrier family 35 member E3 2 2
MIRT674708 FAM73A mitoguardin 1 2 2
MIRT674911 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT675200 ZNF554 zinc finger protein 554 2 2
MIRT675295 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT675374 DCTN5 dynactin subunit 5 2 2
MIRT675446 TPCN2 two pore segment channel 2 2 2
MIRT675473 NUBPL nucleotide binding protein like 2 2
MIRT675672 TMOD2 tropomodulin 2 2 2
MIRT675684 SLC35F5 solute carrier family 35 member F5 2 2
MIRT675789 MED28 mediator complex subunit 28 2 2
MIRT675834 DHODH dihydroorotate dehydrogenase (quinone) 2 4
MIRT675979 FAM126B family with sequence similarity 126 member B 2 2
MIRT676090 DPP9 dipeptidyl peptidase 9 2 2
MIRT676100 ZNF667 zinc finger protein 667 2 2
MIRT676132 RSL1D1 ribosomal L1 domain containing 1 2 2
MIRT676171 HIST1H2BJ histone cluster 1 H2B family member j 2 2
MIRT676243 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT676293 SLC25A37 solute carrier family 25 member 37 2 2
MIRT676310 GTF2H2C GTF2H2 family member C 2 2
MIRT676341 PCCB propionyl-CoA carboxylase beta subunit 2 2
MIRT676389 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676441 PLEKHM3 pleckstrin homology domain containing M3 2 2
MIRT676520 RNF216 ring finger protein 216 2 2
MIRT676584 RDH13 retinol dehydrogenase 13 2 4
MIRT676611 KDSR 3-ketodihydrosphingosine reductase 2 2
MIRT676692 LAIR1 leukocyte associated immunoglobulin like receptor 1 2 2
MIRT676699 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676745 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT676765 SNX2 sorting nexin 2 2 2
MIRT676778 NPHS1 NPHS1, nephrin 2 2
MIRT676799 RILPL1 Rab interacting lysosomal protein like 1 2 2
MIRT676859 TTC4 tetratricopeptide repeat domain 4 2 2
MIRT676881 ENSA endosulfine alpha 2 2
MIRT676948 S1PR3 sphingosine-1-phosphate receptor 3 2 2
MIRT676962 HFE hemochromatosis 2 2
MIRT677010 HINFP histone H4 transcription factor 2 2
MIRT677049 ZNF34 zinc finger protein 34 2 2
MIRT677075 VMAC vimentin type intermediate filament associated coiled-coil protein 2 2
MIRT677097 MFSD11 major facilitator superfamily domain containing 11 2 4
MIRT677130 OGFOD3 2-oxoglutarate and iron dependent oxygenase domain containing 3 2 2
MIRT677170 ZNF786 zinc finger protein 786 2 2
MIRT677219 RASSF6 Ras association domain family member 6 2 2
MIRT677238 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT677408 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT677428 DDX19B DEAD-box helicase 19B 2 2
MIRT677436 NSMCE2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase 2 2
MIRT677467 PDLIM3 PDZ and LIM domain 3 2 2
MIRT677489 GTF2H2 general transcription factor IIH subunit 2 2 2
MIRT677555 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677583 TRIM65 tripartite motif containing 65 2 2
MIRT677602 PRKX protein kinase, X-linked 2 2
MIRT677650 HAUS2 HAUS augmin like complex subunit 2 2 2
MIRT677702 GINS2 GINS complex subunit 2 2 2
MIRT677764 GRM6 glutamate metabotropic receptor 6 2 2
MIRT677788 CEACAM5 carcinoembryonic antigen related cell adhesion molecule 5 2 2
MIRT677814 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT677891 DCP1A decapping mRNA 1A 2 2
MIRT677921 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT677944 ZNF519 zinc finger protein 519 2 2
MIRT677989 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678015 SPIC Spi-C transcription factor 2 2
MIRT678068 UBN2 ubinuclein 2 2 2
MIRT678084 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678128 METTL21A methyltransferase like 21A 2 2
MIRT678147 SLC4A4 solute carrier family 4 member 4 2 2
MIRT678156 IRGQ immunity related GTPase Q 2 2
MIRT678224 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT678327 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678357 PPAP2B phospholipid phosphatase 3 2 2
MIRT678401 MYPN myopalladin 2 2
MIRT678421 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678434 PDE4C phosphodiesterase 4C 2 2
MIRT678444 PARD6G par-6 family cell polarity regulator gamma 2 2
MIRT678493 ARHGEF39 Rho guanine nucleotide exchange factor 39 2 2
MIRT678507 LCTL lactase like 2 2
MIRT678526 P2RX7 purinergic receptor P2X 7 2 2
MIRT678534 TMEM78 transmembrane protein 78 2 2
MIRT678570 CDK4 cyclin dependent kinase 4 2 2
MIRT678608 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT678642 PDCD4 programmed cell death 4 2 2
MIRT678702 TRIP11 thyroid hormone receptor interactor 11 2 2
MIRT678724 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT678764 CEP76 centrosomal protein 76 2 2
MIRT678814 HRH4 histamine receptor H4 2 2
MIRT678880 FAM118A family with sequence similarity 118 member A 2 2
MIRT678905 TTLL12 tubulin tyrosine ligase like 12 2 2
MIRT678946 MYADM myeloid associated differentiation marker 2 2
MIRT678960 ZNF329 zinc finger protein 329 2 2
MIRT678972 OGFOD1 2-oxoglutarate and iron dependent oxygenase domain containing 1 2 2
MIRT679067 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT679072 MANEAL mannosidase endo-alpha like 2 2
MIRT679084 PURB purine rich element binding protein B 2 2
MIRT679115 NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2 2
MIRT679155 ZDHHC15 zinc finger DHHC-type containing 15 2 2
MIRT679177 FFAR4 free fatty acid receptor 4 2 2
MIRT679183 XIAP X-linked inhibitor of apoptosis 2 4
MIRT679224 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679234 LRP10 LDL receptor related protein 10 2 2
MIRT679271 POLM DNA polymerase mu 2 2
MIRT679279 MIPOL1 mirror-image polydactyly 1 2 2
MIRT679345 PPP1R3B protein phosphatase 1 regulatory subunit 3B 2 2
MIRT679352 LRG1 leucine rich alpha-2-glycoprotein 1 2 2
MIRT679365 SIK2 salt inducible kinase 2 2 2
MIRT679493 ZNF106 zinc finger protein 106 2 2
MIRT679600 HILPDA hypoxia inducible lipid droplet associated 2 2
MIRT679636 BRMS1L breast cancer metastasis-suppressor 1 like 2 2
MIRT679650 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT679713 RPL24 ribosomal protein L24 2 2
MIRT679762 TLR6 toll like receptor 6 2 2
MIRT679766 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT679807 APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A 2 2
MIRT679821 TMEM106B transmembrane protein 106B 2 2
MIRT679949 AS3MT arsenite methyltransferase 2 2
MIRT679967 FGFR1OP FGFR1 oncogene partner 2 2
MIRT679992 RUNDC1 RUN domain containing 1 2 2
MIRT680063 CD96 CD96 molecule 2 2
MIRT680079 THAP1 THAP domain containing 1 2 2
MIRT680100 PXMP4 peroxisomal membrane protein 4 2 2
MIRT680138 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT680146 TOP3A DNA topoisomerase III alpha 2 2
MIRT680324 LRRC58 leucine rich repeat containing 58 2 2
MIRT680414 RNF165 ring finger protein 165 2 2
MIRT680451 PDE6A phosphodiesterase 6A 2 2
MIRT680460 TAS2R5 taste 2 receptor member 5 2 2
MIRT683249 WFDC6 WAP four-disulfide core domain 6 2 2
MIRT685083 HPSE heparanase 2 2
MIRT686255 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT687366 NUP155 nucleoporin 155 2 2
MIRT688320 FAM151B family with sequence similarity 151 member B 2 2
MIRT688390 ENAH ENAH, actin regulator 2 2
MIRT688430 DNAL1 dynein axonemal light chain 1 2 2
MIRT688643 CREM cAMP responsive element modulator 2 2
MIRT688739 CNDP1 carnosine dipeptidase 1 2 2
MIRT689335 FPR1 formyl peptide receptor 1 2 4
MIRT690685 PTCHD3 patched domain containing 3 2 2
MIRT690956 APOL1 apolipoprotein L1 2 2
MIRT691727 LARS leucyl-tRNA synthetase 2 2
MIRT693472 ZNF707 zinc finger protein 707 2 2
MIRT693959 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT695487 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT696596 ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2 2
MIRT697024 EPDR1 ependymin related 1 2 2
MIRT698140 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT699106 SNIP1 Smad nuclear interacting protein 1 2 2
MIRT699817 SCN2B sodium voltage-gated channel beta subunit 2 2 2
MIRT701535 NCKAP1 NCK associated protein 1 2 2
MIRT702897 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT705035 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT706023 ZSCAN2 zinc finger and SCAN domain containing 2 2 2
MIRT706039 F2R coagulation factor II thrombin receptor 2 2
MIRT706102 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT706311 CCDC30 coiled-coil domain containing 30 2 2
MIRT706345 STAC2 SH3 and cysteine rich domain 2 2 2
MIRT706400 HAS2 hyaluronan synthase 2 2 2
MIRT706436 LIAS lipoic acid synthetase 2 2
MIRT709396 QRFPR pyroglutamylated RFamide peptide receptor 2 2
MIRT710345 ZNF669 zinc finger protein 669 2 2
MIRT710725 C19orf68 zinc finger SWIM-type containing 9 2 2
MIRT711276 SDR9C7 short chain dehydrogenase/reductase family 9C member 7 2 2
MIRT711862 TRAF2 TNF receptor associated factor 2 2 2
MIRT711921 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT712060 ZBTB34 zinc finger and BTB domain containing 34 2 2
MIRT712593 ADCYAP1 adenylate cyclase activating polypeptide 1 2 2
MIRT712903 TGFA transforming growth factor alpha 2 2
MIRT713297 DCP2 decapping mRNA 2 2 2
MIRT714801 WDPCP WD repeat containing planar cell polarity effector 2 2
MIRT715314 POLR2E RNA polymerase II subunit E 2 2
MIRT715727 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT717606 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT717877 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT718484 TMEM151A transmembrane protein 151A 2 2
MIRT720439 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT721563 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT721698 TFAP2B transcription factor AP-2 beta 2 2
MIRT722525 PLXNA2 plexin A2 2 2
MIRT722758 SIRPB2 signal regulatory protein beta 2 2 2
MIRT723297 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT723407 NLRP10 NLR family pyrin domain containing 10 2 2
MIRT724218 RAB6B RAB6B, member RAS oncogene family 2 2
MIRT724422 FGF2 fibroblast growth factor 2 2 2
MIRT756017 AMBRA1 autophagy and beclin 1 regulator 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-3653 Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3653 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-miR-3653 Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3653 Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3653 Plx-4720 24180719 NSC757438 resistant High Thyroid Cancer cell line (8505c, BCPAP)
hsa-miR-3653 Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-3653 Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (cytosolic RNA)
hsa-miR-3653 Cisplatin 5460033 NSC119875 approved sensitive cell line (CP20)
hsa-miR-3653 Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-miR-3653 Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-3653 Platinum 23939 resistant tissue
hsa-miR-3653 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3653 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-3653-5p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-3653-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)

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