miRTarBase - #MIRT451752


—
pre-miRNA Information
pre-miRNA hsa-mir-4722   
Genomic Coordinates chr16: 88716278 - 88716337
Description Homo sapiens miR-4722 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4722-5p
Sequence 1| GGCAGGAGGGCUGUGCCAGGUUG |23
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1327113111 2 dbSNP
rs774516383 3 dbSNP
rs1353403500 6 dbSNP
rs768834483 11 dbSNP
rs938540081 13 dbSNP
rs557265812 14 dbSNP
rs1411163724 16 dbSNP
rs928486875 20 dbSNP
rs1172652034 21 dbSNP
rs942739465 23 dbSNP
Putative Targets

Gene Information
Gene Symbol LRTM2   
Synonyms -
Description leucine rich repeats and transmembrane domains 2
Transcript NM_001039029   
Other Transcripts NM_001163925 , NM_001163926   
Expression
Putative miRNA Targets on LRTM2
3'UTR of LRTM2
(miRNA target sites are highlighted)		 
>LRTM2|NM_001039029|3'UTR
   1 GCGCCCATCCCCACCCGGCCAGGTAGGAAGGGCGGGGAGAGCACACGGCATTGCTCAGCCACAGCTCCCACCTTGACCCG
  81 GCGCTGGCCACTGCCTCCCCGAGTCCACCCTCCTCCCCGCCCTCCAGCAGACAAGCCACACCGGGTTCTCTCCCTGCACT
 161 TTCGAGGCTCCCTGAAAGCCACCGTGCTGGGGGCTCCTGCTGATGCTCCTGTCTGGGCCAGTAAATCTTTGGAACATGTG
 241 GGGGATCTCCCTAAGCTCTGGCCACAGCAAAGCAAGGAGGTGTGTGCAAGAGGAGGCTTCCGGACTGGGCATTCCCCTGT
 321 CGCCCTTCCTGCCCTGGGGTGGCCATAGCTGGTGACTCTTCCTACCTTGCTGGTCCCACCTCACCTGCATTGAGGGGACG
 401 GGGAGGGAGGGATCTGAGGGATGAAGGTAGATTTCTGAGACTCTCTCCTAAGCCAGAAAGACGTTCTTAACACCCCTGCA
 481 GTGTGAAAGCTGGTCCAGCTCTACAACTGTTGGTACCAATGTGCAAACACACCAGCCCTGCCATCTGGACCCAGCACTCA
 561 GAAACACCATACACCCCTGGCCGACGCCATCATGCCCCTGGATCTGCTATAGGCCACACTGACCACATGCTCCTGGATTC
 641 GCTAATTCACTCACACACCCATTGCATCACCAGTGCGGTCACATGGATTGAAAGAATTAATACACACACACACACACACA
 721 CACTCACACGGTCACACGGAGACCGAGGCTATGAGCGCTCGAACAGCAGAGACATGCTCTTCCCCAGGGGTCTCCCTGAG
 801 ACCACAGAGCCTCTCGCGTGCTCACTGCAATCTTCTCAAGTCAACAGCAGGAAGGAACTCAACCAGTAACACCAGGATCC
 881 TTTGAGATCCTCTAAAGTGGGCCAAAGTGGTGCCCCTGGAGGAGCCCTCCTGTCACCATGGTAACCCTCTCACACCTCTC
 961 CTGCTGGGCTTTCCCGGGATACCACCCAGGGGCCTGGAGCGGCTGCATGTGTGCATGGCGGCCTCCTGAGGACCCAGCCA
1041 CACACCACTGGTGTTGCCTCGGTCCTGCCCACGCATCTCACAGCACCAGGCCCTGTGGGGCCCCCACTGATTCCTCCACA
1121 GCCTGCAGCCTGGCACCGTGACTCTGTGCCTCTCGCCCTCCATCTTCAGTACTCCTGGCCTGTGACTTCAGGGCTGGGAC
1201 TTGGTGGTGCTTTGCCATTGGTGGCACCCTCTGGGGAAAGCAGGTGGCAGGCAGAGAACACGGTGGCTCCCCTGAGGCTC
1281 ATTGCCTGCCAGCTTATTGCAGACAGAGCCCAGGAGCAGGAGCGGGTGGCCACGTGCTGCCCAGAGGCTCCCAGGATGGG
1361 GCCTCTGTTCCCGGGCTTTGTCTGCTCAGTGTGGCTCCCTAGAGCACCCAGCCGGGGCCAAACCAGAGAGTGGGTGGGGA
1441 GCCTGTCTGGGACAGAGCCACCTGCTGCCAAGGCAGTGCAAGTTTTCCAGGTTACCTGTCCCCCTCCCTAGCTCTGCCCC
1521 TCCTCAGAGTGTGAAGATGGTGGGTACCTAGGTGTCATGCTCACAGGCTCAGGAGGCATCAGGCTCGTCCCTGGCTCTGG
1601 GATGGAATCTCGATGGGGGCTCAGGAAGAGGCCAGCAAGAACCCTGAAGCCAAGGGTCTGAGCAGAGGGAGTTGGCAGGC
1681 CTAGCTCCTGTGCCCCACTCCGACCCTCCCTGCTCATGCGGCAGTGGGTGGGTGAGGTGGGCTGGGGGCCTGGAGGAGTG
1761 CCTTTGAGGAGGTCAGTCCTGGCAGGTGGACAGAGGACGCCTGGCATGGGCTGCTTACTGGGACCCCAGGCGGCCCTGGC
1841 CATGGCCACAGTCTTCCTTCTTTTGGCGTGTGGGCTGGTACCAGATCTGGGGATTTTCTAAAGGGACTGGGGGGAGGGGA
1921 GGGCATTGTCAATGGTGGTATCTTTAGCCTGAGACAGAAGATTTTTAAAGGCAAAATTATATTTCTGGTTTGTTGTTTCA
2001 GAAGACCAATAAAGACTGTATTTTCCTATGT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guuGGACCGUGUCGGGAGGACGg 5'
             |||  |||| |:||||||| 
Target 5' aacCCTCTCACACCTCTCCTGCt 3'
 943 - 965 172.00 -24.40
2 
miRNA  3' guuGGACCGUGUCGGGAGGACGg 5'
             ||||| : ||||||||||: 
Target 5' gccCCTGGAGGAGCCCTCCTGTc 3'
 912 - 934 164.00 -34.10
3 
miRNA  3' guUGGACCGUGUCGGGAGGACGg 5'
            |||  ||  :|  ||||||| 
Target 5' ccACCGTGCTGGGGGCTCCTGCt 3'
 179 - 201 153.00 -18.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30493552 4 COSMIC
COSN5319494 15 COSMIC
COSN30459483 16 COSMIC
COSN30180334 17 COSMIC
COSN30187149 17 COSMIC
COSN26983184 19 COSMIC
COSN30481927 23 COSMIC
COSN31511525 28 COSMIC
COSN30467588 32 COSMIC
COSN30515317 34 COSMIC
COSN23013621 57 COSMIC
COSN28679167 79 COSMIC
COSN15911395 165 COSMIC
COSN16938719 303 COSMIC
COSN21689141 308 COSMIC
COSN7320973 371 COSMIC
COSN15668301 404 COSMIC
COSN15661437 430 COSMIC
COSN24682005 730 COSMIC
COSN25901827 738 COSMIC
COSN31538875 808 COSMIC
COSN16619285 817 COSMIC
COSN16130640 858 COSMIC
COSN31578791 901 COSMIC
COSN30541315 925 COSMIC
COSN31572563 931 COSMIC
COSN28674084 939 COSMIC
COSN28657045 1073 COSMIC
COSN1145890 1139 COSMIC
COSN7320975 1152 COSMIC
COSN5796108 1170 COSMIC
COSN8704644 1356 COSMIC
COSN27496044 1588 COSMIC
COSN29950127 1620 COSMIC
COSN20092471 1629 COSMIC
COSN20739314 1670 COSMIC
COSN31550359 1868 COSMIC
COSN31543170 1931 COSMIC
COSN26554218 1948 COSMIC
COSN8585781 2020 COSMIC
COSN31577343 2027 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs375560200 3 dbSNP
rs368281047 4 dbSNP
rs879021839 6 dbSNP
rs1219886947 7 dbSNP
rs1207037783 9 dbSNP
rs751381663 15 dbSNP
rs1465639849 16 dbSNP
rs759415155 17 dbSNP
rs749530595 18 dbSNP
rs752644815 20 dbSNP
rs372554979 21 dbSNP
rs1423744851 23 dbSNP
rs1188928005 24 dbSNP
rs1370549442 31 dbSNP
rs151191165 34 dbSNP
rs140355519 35 dbSNP
rs369511827 41 dbSNP
rs1458308005 42 dbSNP
rs145529491 47 dbSNP
rs1400954332 48 dbSNP
rs747382509 57 dbSNP
rs1230478826 63 dbSNP
rs1314832626 65 dbSNP
rs1019264415 68 dbSNP
rs1227594323 72 dbSNP
rs755456043 75 dbSNP
rs781712243 76 dbSNP
rs564381412 80 dbSNP
rs961360099 83 dbSNP
rs990254334 84 dbSNP
rs1239678987 95 dbSNP
rs1207691433 98 dbSNP
rs910511209 101 dbSNP
rs972507289 102 dbSNP
rs1224463556 115 dbSNP
rs1352102216 116 dbSNP
rs1027183972 119 dbSNP
rs1385995752 122 dbSNP
rs528356465 123 dbSNP
rs896335116 124 dbSNP
rs1379192518 126 dbSNP
rs1299550857 127 dbSNP
rs1386363248 131 dbSNP
rs199964422 133 dbSNP
rs1366663588 136 dbSNP
rs990574652 137 dbSNP
rs769086512 143 dbSNP
rs949274209 144 dbSNP
rs1358600857 146 dbSNP
rs1157959477 149 dbSNP
rs1353656510 153 dbSNP
rs546854029 164 dbSNP
rs982020636 165 dbSNP
rs1196317459 167 dbSNP
rs181392888 178 dbSNP
rs934695759 184 dbSNP
rs371565323 185 dbSNP
rs550648685 190 dbSNP
rs1459241982 191 dbSNP
rs1263176017 194 dbSNP
rs574367146 195 dbSNP
rs7954520 200 dbSNP
rs539384056 207 dbSNP
rs894792840 208 dbSNP
rs1232838332 209 dbSNP
rs777192288 211 dbSNP
rs1013290812 213 dbSNP
rs1303650041 214 dbSNP
rs1406604307 216 dbSNP
rs1046280844 220 dbSNP
rs947474117 222 dbSNP
rs1049896733 223 dbSNP
rs1297509436 230 dbSNP
rs889987061 232 dbSNP
rs1400468729 235 dbSNP
rs902467030 240 dbSNP
rs146521480 241 dbSNP
rs1166897429 244 dbSNP
rs1377895837 245 dbSNP
rs1020326585 250 dbSNP
rs568050967 256 dbSNP
rs1017728771 261 dbSNP
rs772748843 268 dbSNP
rs201498991 275 dbSNP
rs965054979 275 dbSNP
rs186891929 277 dbSNP
rs1199992463 280 dbSNP
rs534991278 281 dbSNP
rs553188804 282 dbSNP
rs952440058 288 dbSNP
rs1444064048 292 dbSNP
rs1011962781 302 dbSNP
rs983704132 303 dbSNP
rs1382808903 310 dbSNP
rs1023409898 318 dbSNP
rs970557070 320 dbSNP
rs1315518825 322 dbSNP
rs773890398 323 dbSNP
rs761076112 324 dbSNP
rs923822144 327 dbSNP
rs956654314 332 dbSNP
rs531275850 340 dbSNP
rs1196911111 353 dbSNP
rs949058679 353 dbSNP
rs1046017525 357 dbSNP
rs914594267 360 dbSNP
rs947440037 385 dbSNP
rs999364715 390 dbSNP
rs1457449267 391 dbSNP
rs541920598 400 dbSNP
rs1183641404 401 dbSNP
rs1341196956 403 dbSNP
rs1282428685 404 dbSNP
rs535247570 404 dbSNP
rs1340566572 409 dbSNP
rs1006749080 410 dbSNP
rs1423120617 415 dbSNP
rs911392232 419 dbSNP
rs1331593105 425 dbSNP
rs944222696 428 dbSNP
rs556992945 436 dbSNP
rs115189587 455 dbSNP
rs997621774 457 dbSNP
rs897359697 459 dbSNP
rs1463744938 463 dbSNP
rs1169596973 464 dbSNP
rs1176893681 472 dbSNP
rs1439143835 473 dbSNP
rs1030300091 474 dbSNP
rs1449639422 481 dbSNP
rs190092286 488 dbSNP
rs950701670 497 dbSNP
rs1300548952 499 dbSNP
rs994447263 504 dbSNP
rs1048505254 505 dbSNP
rs1397541175 507 dbSNP
rs888138803 517 dbSNP
rs1011930369 521 dbSNP
rs1360017174 522 dbSNP
rs1023378854 542 dbSNP
rs983693993 544 dbSNP
rs763301909 546 dbSNP
rs1296749874 554 dbSNP
rs1342709258 568 dbSNP
rs970525850 573 dbSNP
rs1323256255 575 dbSNP
rs909503760 580 dbSNP
rs1003749461 583 dbSNP
rs776085714 584 dbSNP
rs553519826 586 dbSNP
rs564310310 587 dbSNP
rs1477136336 590 dbSNP
rs759287251 596 dbSNP
rs949116376 602 dbSNP
rs141169532 609 dbSNP
rs968746127 610 dbSNP
rs540531609 620 dbSNP
rs923601449 622 dbSNP
rs1482886644 628 dbSNP
rs1284285616 631 dbSNP
rs1186973705 634 dbSNP
rs1225143062 639 dbSNP
rs1342486824 641 dbSNP
rs935036817 642 dbSNP
rs766663850 652 dbSNP
rs1053614132 657 dbSNP
rs1296895731 660 dbSNP
rs1399875600 661 dbSNP
rs1192631368 662 dbSNP
rs1429620191 663 dbSNP
rs1412805048 672 dbSNP
rs560173776 677 dbSNP
rs561869405 677 dbSNP
rs1415776855 682 dbSNP
rs1173383915 684 dbSNP
rs1039517849 688 dbSNP
rs1358006571 690 dbSNP
rs1191444768 695 dbSNP
rs147240417 695 dbSNP
rs375226972 695 dbSNP
rs1242595307 697 dbSNP
rs997565985 698 dbSNP
rs1358579298 702 dbSNP
rs137889817 702 dbSNP
rs1440186354 702 dbSNP
rs1445995489 702 dbSNP
rs372477361 702 dbSNP
rs770889560 702 dbSNP
rs886436223 702 dbSNP
rs1337654098 707 dbSNP
rs1342900300 712 dbSNP
rs78537235 713 dbSNP
rs1477359135 719 dbSNP
rs1277908435 722 dbSNP
rs1041585748 723 dbSNP
rs1188202937 725 dbSNP
rs918776069 730 dbSNP
rs930205055 731 dbSNP
rs763969051 734 dbSNP
rs550711315 738 dbSNP
rs1288129164 739 dbSNP
rs1011900800 745 dbSNP
rs1044715569 746 dbSNP
rs906271058 754 dbSNP
rs377061752 756 dbSNP
rs981824144 757 dbSNP
rs923717394 758 dbSNP
rs1003310420 761 dbSNP
rs539118799 762 dbSNP
rs892322831 775 dbSNP
rs1461357070 777 dbSNP
rs865943221 780 dbSNP
rs1172468165 784 dbSNP
rs1403491162 785 dbSNP
rs771530873 789 dbSNP
rs1011237932 798 dbSNP
rs989133135 806 dbSNP
rs1445899554 808 dbSNP
rs756979083 812 dbSNP
rs767413591 816 dbSNP
rs753992994 817 dbSNP
rs1018305277 821 dbSNP
rs1418365854 825 dbSNP
rs942596179 826 dbSNP
rs571111127 829 dbSNP
rs778829106 830 dbSNP
rs976891489 838 dbSNP
rs900996632 866 dbSNP
rs749470448 869 dbSNP
rs1350768923 873 dbSNP
rs551389052 875 dbSNP
rs1321682708 876 dbSNP
rs1293107580 877 dbSNP
rs930197264 885 dbSNP
rs182280277 887 dbSNP
rs1374752133 888 dbSNP
rs1292069535 891 dbSNP
rs535030029 893 dbSNP
rs1241028748 895 dbSNP
rs1392124494 897 dbSNP
rs546841479 899 dbSNP
rs1000540553 900 dbSNP
rs1299634031 901 dbSNP
rs1433990444 901 dbSNP
rs1364938081 905 dbSNP
rs1051829386 911 dbSNP
rs564890089 914 dbSNP
rs1157942556 917 dbSNP
rs1419262155 919 dbSNP
rs1252191391 926 dbSNP
rs187275072 933 dbSNP
rs1189886153 936 dbSNP
rs948326969 937 dbSNP
rs11061994 939 dbSNP
rs1270318571 941 dbSNP
rs1239252898 946 dbSNP
rs906239978 954 dbSNP
rs1285343805 957 dbSNP
rs1453172826 959 dbSNP
rs1240074123 962 dbSNP
rs1318997429 965 dbSNP
rs1299438066 969 dbSNP
rs1219106322 976 dbSNP
rs1344634395 977 dbSNP
rs150192509 978 dbSNP
rs1303701082 984 dbSNP
rs1016241919 986 dbSNP
rs1358107869 991 dbSNP
rs1287824134 993 dbSNP
rs138747752 1000 dbSNP
rs1365237470 1001 dbSNP
rs557253639 1001 dbSNP
rs753293962 1002 dbSNP
rs1430350252 1004 dbSNP
rs80107440 1009 dbSNP
rs1012465771 1010 dbSNP
rs1487573501 1014 dbSNP
rs1377875671 1017 dbSNP
rs892287330 1020 dbSNP
rs1010707571 1021 dbSNP
rs1022138944 1024 dbSNP
rs889011880 1027 dbSNP
rs756950708 1029 dbSNP
rs1254556234 1031 dbSNP
rs1232726320 1034 dbSNP
rs543445386 1044 dbSNP
rs1018274432 1046 dbSNP
rs1338400189 1048 dbSNP
rs558181896 1050 dbSNP
rs965428648 1054 dbSNP
rs977236820 1057 dbSNP
rs1382359975 1058 dbSNP
rs1025759694 1062 dbSNP
rs1031142792 1063 dbSNP
rs956435072 1065 dbSNP
rs79684715 1073 dbSNP
rs984231264 1074 dbSNP
rs914881013 1079 dbSNP
rs771181979 1080 dbSNP
rs975350960 1082 dbSNP
rs1447745709 1083 dbSNP
rs1333456054 1085 dbSNP
rs1430389298 1088 dbSNP
rs563154569 1090 dbSNP
rs922534901 1091 dbSNP
rs1271694533 1101 dbSNP
rs1461967473 1103 dbSNP
rs1205388051 1107 dbSNP
rs948296003 1108 dbSNP
rs1250693483 1112 dbSNP
rs547316854 1114 dbSNP
rs540544016 1120 dbSNP
rs1358349640 1125 dbSNP
rs1309914375 1128 dbSNP
rs1226419389 1130 dbSNP
rs561930750 1133 dbSNP
rs573902870 1138 dbSNP
rs189563926 1139 dbSNP
rs1396144502 1140 dbSNP
rs1235962901 1142 dbSNP
rs1463942335 1145 dbSNP
rs562526644 1155 dbSNP
rs11061995 1156 dbSNP
rs899162831 1162 dbSNP
rs1238608705 1165 dbSNP
rs1012685428 1170 dbSNP
rs551182626 1175 dbSNP
rs1161861467 1183 dbSNP
rs1413440071 1185 dbSNP
rs1196344560 1186 dbSNP
rs1341439445 1187 dbSNP
rs1466353064 1204 dbSNP
rs781354035 1208 dbSNP
rs1244679486 1216 dbSNP
rs1359531427 1222 dbSNP
rs1316724810 1229 dbSNP
rs1444047897 1230 dbSNP
rs1335578191 1238 dbSNP
rs769445798 1244 dbSNP
rs1398375144 1251 dbSNP
rs1393479020 1255 dbSNP
rs775026475 1262 dbSNP
rs762389802 1263 dbSNP
rs1465207232 1272 dbSNP
rs748348362 1279 dbSNP
rs1040352004 1280 dbSNP
rs560095661 1283 dbSNP
rs527250651 1286 dbSNP
rs1157102363 1289 dbSNP
rs748697345 1303 dbSNP
rs956879336 1309 dbSNP
rs998161657 1311 dbSNP
rs1010650298 1314 dbSNP
rs1439333829 1317 dbSNP
rs546902788 1321 dbSNP
rs1340957833 1323 dbSNP
rs763598867 1324 dbSNP
rs1490374791 1325 dbSNP
rs1293265532 1326 dbSNP
rs148230688 1333 dbSNP
rs774267693 1334 dbSNP
rs1005623363 1340 dbSNP
rs1279756605 1341 dbSNP
rs568446333 1347 dbSNP
rs1343948873 1348 dbSNP
rs969571566 1353 dbSNP
rs980982377 1359 dbSNP
rs928204400 1373 dbSNP
rs961252194 1374 dbSNP
rs770164163 1377 dbSNP
rs987800722 1389 dbSNP
rs1037772267 1390 dbSNP
rs920705681 1396 dbSNP
rs1185981486 1398 dbSNP
rs1237402152 1404 dbSNP
rs913571296 1414 dbSNP
rs946435192 1415 dbSNP
rs1196262990 1416 dbSNP
rs1421784526 1419 dbSNP
rs1043518898 1420 dbSNP
rs1490504249 1428 dbSNP
rs1270928156 1434 dbSNP
rs1477593899 1435 dbSNP
rs1173235547 1436 dbSNP
rs910382138 1436 dbSNP
rs1445910413 1437 dbSNP
rs1284524511 1442 dbSNP
rs943215116 1443 dbSNP
rs906548032 1446 dbSNP
rs1003718032 1451 dbSNP
rs1040617326 1452 dbSNP
rs901719751 1459 dbSNP
rs180862744 1461 dbSNP
rs1047047238 1462 dbSNP
rs551198635 1466 dbSNP
rs143725790 1470 dbSNP
rs1430187332 1476 dbSNP
rs887132680 1480 dbSNP
rs1401666149 1484 dbSNP
rs868546698 1488 dbSNP
rs1345798142 1489 dbSNP
rs1011512818 1491 dbSNP
rs1403676584 1496 dbSNP
rs1175499145 1499 dbSNP
rs1268846737 1501 dbSNP
rs767185170 1510 dbSNP
rs1017009060 1516 dbSNP
rs1431438784 1518 dbSNP
rs969453521 1520 dbSNP
rs964104575 1521 dbSNP
rs1242140881 1525 dbSNP
rs1002289074 1530 dbSNP
rs996626702 1531 dbSNP
rs1459732106 1534 dbSNP
rs1233437328 1535 dbSNP
rs763105632 1540 dbSNP
rs1262101321 1541 dbSNP
rs138456996 1545 dbSNP
rs1204775772 1552 dbSNP
rs1029292988 1568 dbSNP
rs557931418 1578 dbSNP
rs118070468 1582 dbSNP
rs1199388157 1584 dbSNP
rs908482852 1585 dbSNP
rs962562371 1587 dbSNP
rs534156340 1588 dbSNP
rs1470124976 1594 dbSNP
rs913547500 1595 dbSNP
rs1168263322 1597 dbSNP
rs1409259544 1602 dbSNP
rs1420102271 1612 dbSNP
rs11061996 1613 dbSNP
rs1442228734 1621 dbSNP
rs915765884 1629 dbSNP
rs1373953304 1632 dbSNP
rs564647053 1637 dbSNP
rs1428152246 1644 dbSNP
rs1242222495 1649 dbSNP
rs1183749538 1651 dbSNP
rs1462950825 1653 dbSNP
rs574018425 1659 dbSNP
rs979167813 1661 dbSNP
rs1475211120 1662 dbSNP
rs1308644270 1664 dbSNP
rs752969266 1673 dbSNP
rs1243952983 1680 dbSNP
rs75024051 1691 dbSNP
rs1172045057 1694 dbSNP
rs878947191 1697 dbSNP
rs185257156 1702 dbSNP
rs568133445 1703 dbSNP
rs1296277681 1709 dbSNP
rs74374144 1717 dbSNP
rs757835072 1720 dbSNP
rs545096744 1721 dbSNP
rs559954492 1722 dbSNP
rs1425148521 1724 dbSNP
rs1328970152 1730 dbSNP
rs899999705 1737 dbSNP
rs1481160336 1745 dbSNP
rs1235102711 1746 dbSNP
rs1048149056 1748 dbSNP
rs887102195 1749 dbSNP
rs1292538997 1750 dbSNP
rs79967594 1759 dbSNP
rs1242871285 1772 dbSNP
rs1284482327 1773 dbSNP
rs1306547867 1774 dbSNP
rs1038339190 1784 dbSNP
rs1003910188 1788 dbSNP
rs905264948 1797 dbSNP
rs1373705157 1799 dbSNP
rs542252544 1800 dbSNP
rs781574664 1810 dbSNP
rs1402979001 1814 dbSNP
rs1035179928 1818 dbSNP
rs1303279149 1824 dbSNP
rs1458977768 1824 dbSNP
rs974021004 1825 dbSNP
rs896668077 1832 dbSNP
rs1009817287 1833 dbSNP
rs1450033697 1838 dbSNP
rs1197928065 1839 dbSNP
rs1021659271 1841 dbSNP
rs968297267 1842 dbSNP
rs1270203351 1846 dbSNP
rs1224891937 1848 dbSNP
rs969952323 1868 dbSNP
rs190071102 1869 dbSNP
rs1216698003 1871 dbSNP
rs1317322421 1876 dbSNP
rs1289944500 1880 dbSNP
rs1221437745 1882 dbSNP
rs746205791 1888 dbSNP
rs372898068 1889 dbSNP
rs550948799 1891 dbSNP
rs375797975 1894 dbSNP
rs976262065 1901 dbSNP
rs879592794 1908 dbSNP
rs1458260498 1909 dbSNP
rs533330894 1910 dbSNP
rs983315610 1911 dbSNP
rs909096277 1915 dbSNP
rs941972192 1917 dbSNP
rs760684631 1919 dbSNP
rs905230564 1929 dbSNP
rs367840722 1933 dbSNP
rs3803162 1935 dbSNP
rs1466456456 1936 dbSNP
rs547297208 1938 dbSNP
rs1201601059 1943 dbSNP
rs1316818933 1949 dbSNP
rs1010114757 1950 dbSNP
rs752095517 1951 dbSNP
rs867147813 1954 dbSNP
rs1021136046 1962 dbSNP
rs1246013279 1970 dbSNP
rs1263692392 2001 dbSNP
rs1050819176 2005 dbSNP
rs756756491 2018 dbSNP
rs1324200079 2029 dbSNP
rs768150924 2030 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guuGGACCGUGUCGGGAGGACgg 5'
             :||  |||| |:||||||  
Target 5' ---UCU--CACACCUCUCCUG-- 3'
 		1 - 16
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000543818.1 | 3UTR | UCUCACACCUCUCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
451 hsa-miR-4722-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT054597 SNCG synuclein gamma 3 1
MIRT082999 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT140189 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT143139 MGRN1 mahogunin ring finger 1 2 2
MIRT150114 MIDN midnolin 2 2
MIRT153929 NCOA3 nuclear receptor coactivator 3 2 2
MIRT200999 ZNF805 zinc finger protein 805 2 2
MIRT214002 DCP2 decapping mRNA 2 2 2
MIRT292480 ZNF507 zinc finger protein 507 2 2
MIRT325575 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT370125 TRIB3 tribbles pseudokinase 3 2 2
MIRT442143 C20orf197 chromosome 20 open reading frame 197 2 2
MIRT443495 MXI1 MAX interactor 1, dimerization protein 2 6
MIRT443526 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 4
MIRT445688 GJB1 gap junction protein beta 1 2 2
MIRT447187 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 4
MIRT448070 SLC25A43 solute carrier family 25 member 43 2 2
MIRT448198 B4GALT7 beta-1,4-galactosyltransferase 7 2 4
MIRT451251 ZNF444 zinc finger protein 444 2 2
MIRT451291 ZNF101 zinc finger protein 101 2 4
MIRT451455 HSD11B1L hydroxysteroid 11-beta dehydrogenase 1 like 2 2
MIRT451503 ALOX15 arachidonate 15-lipoxygenase 2 2
MIRT451752 LRTM2 leucine rich repeats and transmembrane domains 2 2 2
MIRT452056 ZNF585B zinc finger protein 585B 2 12
MIRT452211 HAVCR1 hepatitis A virus cellular receptor 1 2 8
MIRT452575 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT452724 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 4
MIRT452736 PTGES3L prostaglandin E synthase 3 like 2 8
MIRT452760 TCEA3 transcription elongation factor A3 2 4
MIRT452868 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT452879 PRSS45 protease, serine 45 2 2
MIRT452967 ZNF844 zinc finger protein 844 2 8
MIRT453023 ZNF527 zinc finger protein 527 2 4
MIRT453060 TANGO2 transport and golgi organization 2 homolog 2 2
MIRT453480 PITPNM3 PITPNM family member 3 2 2
MIRT453706 TBX20 T-box 20 2 2
MIRT453904 GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 2 4
MIRT453967 ATP13A4 ATPase 13A4 2 6
MIRT454061 SLC35E3 solute carrier family 35 member E3 2 2
MIRT454246 CCDC125 coiled-coil domain containing 125 2 2
MIRT454481 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454529 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454986 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT455482 NPY4R neuropeptide Y receptor Y4 2 2
MIRT455698 ZMYM1 zinc finger MYM-type containing 1 2 4
MIRT455929 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT456207 LIX1L limb and CNS expressed 1 like 2 6
MIRT456274 HRNR hornerin 2 2
MIRT456417 MTRF1L mitochondrial translational release factor 1 like 2 2
MIRT456732 TMEM239 transmembrane protein 239 2 2
MIRT456993 ZNF669 zinc finger protein 669 2 4
MIRT457132 ASPH aspartate beta-hydroxylase 2 2
MIRT457239 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457283 PCDHB11 protocadherin beta 11 2 2
MIRT457338 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 2 2
MIRT457471 SLC35F6 solute carrier family 35 member F6 2 2
MIRT457542 ZC3H6 zinc finger CCCH-type containing 6 2 2
MIRT457640 ZNF69 zinc finger protein 69 2 2
MIRT457981 APAF1 apoptotic peptidase activating factor 1 2 4
MIRT458183 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT458453 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT458461 SNX22 sorting nexin 22 2 6
MIRT458507 GSG2 histone H3 associated protein kinase 2 6
MIRT458557 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT458637 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT458783 ZNF786 zinc finger protein 786 2 2
MIRT458795 CYP8B1 cytochrome P450 family 8 subfamily B member 1 2 2
MIRT459052 ZNF490 zinc finger protein 490 2 2
MIRT459398 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT459547 BTD biotinidase 2 4
MIRT460145 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT460163 CCL16 C-C motif chemokine ligand 16 2 2
MIRT460243 IL17RB interleukin 17 receptor B 2 4
MIRT460356 TXNDC16 thioredoxin domain containing 16 2 4
MIRT460512 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460613 FEM1A fem-1 homolog A 2 2
MIRT460713 FN3KRP fructosamine 3 kinase related protein 2 2
MIRT460799 VPS33A VPS33A, CORVET/HOPS core subunit 2 2
MIRT460829 EGF epidermal growth factor 2 4
MIRT460931 NOA1 nitric oxide associated 1 2 2
MIRT461113 PACSIN2 protein kinase C and casein kinase substrate in neurons 2 2 2
MIRT461124 RAB36 RAB36, member RAS oncogene family 2 4
MIRT461150 RAB2A RAB2A, member RAS oncogene family 2 2
MIRT461200 TIPIN TIMELESS interacting protein 2 2
MIRT461463 SLC19A3 solute carrier family 19 member 3 2 2
MIRT461812 SNAP23 synaptosome associated protein 23 2 2
MIRT462078 MSANTD2 Myb/SANT DNA binding domain containing 2 2 2
MIRT462213 MLH1 mutL homolog 1 2 2
MIRT462308 TMEM109 transmembrane protein 109 2 2
MIRT462430 GTPBP10 GTP binding protein 10 2 4
MIRT462503 MTFMT mitochondrial methionyl-tRNA formyltransferase 2 8
MIRT462535 PLLP plasmolipin 2 6
MIRT462691 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT462908 ZNRF3 zinc and ring finger 3 2 2
MIRT462964 ZNF788 zinc finger family member 788 2 2
MIRT463066 ZNF639 zinc finger protein 639 2 4
MIRT463868 WNT7B Wnt family member 7B 2 2
MIRT464036 WASL Wiskott-Aldrich syndrome like 2 2
MIRT464115 VPS35 VPS35, retromer complex component 2 2
MIRT464507 UCK2 uridine-cytidine kinase 2 2 2
MIRT464931 TXLNA taxilin alpha 2 2
MIRT465203 TRMT6 tRNA methyltransferase 6 2 2
MIRT465579 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT466090 TMEM184C transmembrane protein 184C 2 2
MIRT466208 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT467010 SSBP2 single stranded DNA binding protein 2 2 4
MIRT467159 SREBF2 sterol regulatory element binding transcription factor 2 2 2
MIRT467754 SLC35F1 solute carrier family 35 member F1 2 4
MIRT467843 SLC25A34 solute carrier family 25 member 34 2 2
MIRT468139 SH3BP4 SH3 domain binding protein 4 2 2
MIRT469034 RNF38 ring finger protein 38 2 6
MIRT469062 RNF20 ring finger protein 20 2 2
MIRT469280 RHOA ras homolog family member A 2 2
MIRT469584 RAP2B RAP2B, member of RAS oncogene family 2 6
MIRT470108 PTBP2 polypyrimidine tract binding protein 2 2 6
MIRT470186 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT470282 PRDX5 peroxiredoxin 5 2 2
MIRT471059 PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2 2
MIRT471160 PHF12 PHD finger protein 12 2 2
MIRT471337 PERP PERP, TP53 apoptosis effector 2 2
MIRT471573 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT471643 PANK2 pantothenate kinase 2 2 4
MIRT472028 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT472319 NF2 neurofibromin 2 2 2
MIRT472821 MTMR10 myotubularin related protein 10 2 4
MIRT473101 MLXIP MLX interacting protein 2 2
MIRT473292 MFRP membrane frizzled-related protein 2 2
MIRT473635 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT474108 LMBR1L limb development membrane protein 1 like 2 2
MIRT474615 KLF2 Kruppel like factor 2 2 4
MIRT474666 KLF13 Kruppel like factor 13 2 4
MIRT474696 KIF5A kinesin family member 5A 2 2
MIRT474818 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT475280 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT475650 HIF3A hypoxia inducible factor 3 alpha subunit 2 4
MIRT475703 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT475762 HDLBP high density lipoprotein binding protein 2 2
MIRT476382 GID4 GID complex subunit 4 homolog 2 4
MIRT476398 GDE1 glycerophosphodiester phosphodiesterase 1 2 8
MIRT476446 GBA2 glucosylceramidase beta 2 2 2
MIRT476804 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT477074 FAM208A family with sequence similarity 208 member A 2 4
MIRT477152 FADS1 fatty acid desaturase 1 2 8
MIRT477247 ERGIC2 ERGIC and golgi 2 2 2
MIRT477543 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT478088 DLGAP4 DLG associated protein 4 2 2
MIRT478226 DDX52 DExD-box helicase 52 2 2
MIRT478751 CS citrate synthase 2 2
MIRT479196 CLCN5 chloride voltage-gated channel 5 2 6
MIRT479908 CCDC117 coiled-coil domain containing 117 2 6
MIRT480198 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2 2
MIRT480437 C17orf49 chromosome 17 open reading frame 49 2 2
MIRT480722 BPTF bromodomain PHD finger transcription factor 2 4
MIRT481096 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT481429 ASB6 ankyrin repeat and SOCS box containing 6 2 4
MIRT482080 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT482256 AGO3 argonaute 3, RISC catalytic component 2 4
MIRT482342 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482463 ADAR adenosine deaminase, RNA specific 2 4
MIRT483780 CASKIN1 CASK interacting protein 1 2 4
MIRT484384 ZNF710 zinc finger protein 710 2 4
MIRT485110 SHISA6 shisa family member 6 2 2
MIRT487430 ZSCAN25 zinc finger and SCAN domain containing 25 2 4
MIRT487519 GXYLT2 glucoside xylosyltransferase 2 2 4
MIRT487911 FBXO44 F-box protein 44 2 2
MIRT487961 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT488496 SFMBT2 Scm like with four mbt domains 2 2 4
MIRT488595 SPN sialophorin 2 2
MIRT488994 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT490265 HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2 2
MIRT490835 ADD2 adducin 2 2 2
MIRT490863 UPK2 uroplakin 2 2 2
MIRT491481 APC2 APC2, WNT signaling pathway regulator 2 6
MIRT491713 C17orf85 nuclear cap binding subunit 3 2 2
MIRT492571 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 4
MIRT495792 GRK1 G protein-coupled receptor kinase 1 2 4
MIRT496285 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT496791 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT498599 KRT8 keratin 8 2 2
MIRT498734 SNTN sentan, cilia apical structure protein 2 6
MIRT500016 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501616 PISD phosphatidylserine decarboxylase 2 2
MIRT502160 KIAA1109 KIAA1109 2 4
MIRT502319 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT503238 C16orf74 chromosome 16 open reading frame 74 2 4
MIRT503427 SLC25A45 solute carrier family 25 member 45 2 6
MIRT503871 CBS cystathionine-beta-synthase 2 2
MIRT505181 USP46 ubiquitin specific peptidase 46 2 4
MIRT505402 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 4
MIRT507338 FAM168A family with sequence similarity 168 member A 2 2
MIRT508899 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT516506 SYTL3 synaptotagmin like 3 2 4
MIRT516528 MIXL1 Mix paired-like homeobox 2 2
MIRT517214 PRIM1 DNA primase subunit 1 2 4
MIRT517972 DSCR3 DSCR3 arrestin fold containing 2 2
MIRT518902 CDC14B cell division cycle 14B 2 2
MIRT519272 ZNF141 zinc finger protein 141 2 4
MIRT520332 UBXN2A UBX domain protein 2A 2 2
MIRT524620 C7orf73 short transmembrane mitochondrial protein 1 2 2
MIRT525322 SNX29 sorting nexin 29 2 2
MIRT529045 CDK18 cyclin dependent kinase 18 2 2
MIRT533852 TEAD1 TEA domain transcription factor 1 2 2
MIRT536401 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT546465 SLC25A44 solute carrier family 25 member 44 2 2
MIRT548657 CTTNBP2NL CTTNBP2 N-terminal like 2 2
MIRT549906 ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 2 2
MIRT550418 ORC4 origin recognition complex subunit 4 2 2
MIRT550571 SLC2A5 solute carrier family 2 member 5 2 2
MIRT550592 CBY3 chibby family member 3 2 2
MIRT550771 ENOX2 ecto-NOX disulfide-thiol exchanger 2 2 4
MIRT550988 RBM38 RNA binding motif protein 38 2 2
MIRT551332 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT551393 MRI1 methylthioribose-1-phosphate isomerase 1 2 4
MIRT553919 STK11IP serine/threonine kinase 11 interacting protein 2 2
MIRT554616 RPS6KA3 ribosomal protein S6 kinase A3 2 2
MIRT559202 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT559537 ARHGAP1 Rho GTPase activating protein 1 2 2
MIRT559650 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT560141 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT562318 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT564496 PUS3 pseudouridylate synthase 3 2 2
MIRT566253 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT567619 FAM210A family with sequence similarity 210 member A 2 2
MIRT567950 CREBZF CREB/ATF bZIP transcription factor 2 2
MIRT568011 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT574884 Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 2 2
MIRT575559 Cd99 CD99 antigen 2 2
MIRT576147 Hmox1 heme oxygenase 1 2 2
MIRT608269 NOP14 NOP14 nucleolar protein 2 2
MIRT610850 ARSA arylsulfatase A 2 2
MIRT614128 THAP1 THAP domain containing 1 2 6
MIRT614722 TEAD3 TEA domain transcription factor 3 2 2
MIRT615227 BROX BRO1 domain and CAAX motif containing 2 2
MIRT617419 ANP32E acidic nuclear phosphoprotein 32 family member E 2 4
MIRT618170 ZNF681 zinc finger protein 681 2 4
MIRT618873 MBL2 mannose binding lectin 2 2 2
MIRT618974 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619184 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620310 AQP6 aquaporin 6 2 2
MIRT620422 CD3EAP CD3e molecule associated protein 2 2
MIRT620451 CENPN centromere protein N 2 2
MIRT621649 UBXN2B UBX domain protein 2B 2 2
MIRT621951 STX7 syntaxin 7 2 2
MIRT622815 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT623357 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT624916 FBXW2 F-box and WD repeat domain containing 2 2 2
MIRT624979 ZNF665 zinc finger protein 665 2 4
MIRT625490 SMAD9 SMAD family member 9 2 2
MIRT625587 KLHL23 kelch like family member 23 2 2
MIRT625656 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT625879 INADL PATJ, crumbs cell polarity complex component 2 2
MIRT626231 ZNF749 zinc finger protein 749 2 2
MIRT626621 SLC30A6 solute carrier family 30 member 6 2 2
MIRT626986 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627055 DCTN6 dynactin subunit 6 2 2
MIRT627674 RPL28 ribosomal protein L28 2 2
MIRT627887 OLFML2A olfactomedin like 2A 2 2
MIRT627981 NDRG3 NDRG family member 3 2 2
MIRT628313 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT628343 CCDC68 coiled-coil domain containing 68 2 2
MIRT631946 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632270 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT636356 OGFRL1 opioid growth factor receptor like 1 2 2
MIRT639187 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT639668 PPEF2 protein phosphatase with EF-hand domain 2 2 6
MIRT639865 STK40 serine/threonine kinase 40 2 2
MIRT642230 RABAC1 Rab acceptor 1 2 2
MIRT642364 ZNF581 zinc finger protein 581 2 2
MIRT646793 EVC2 EvC ciliary complex subunit 2 2 2
MIRT646977 KCNJ11 potassium voltage-gated channel subfamily J member 11 2 2
MIRT647068 BRIX1 BRX1, biogenesis of ribosomes 2 4
MIRT647310 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT648993 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT649132 SPATA5 spermatogenesis associated 5 2 2
MIRT650524 CCDC77 coiled-coil domain containing 77 2 4
MIRT650986 ZNF770 zinc finger protein 770 2 2
MIRT655721 NRXN3 neurexin 3 2 2
MIRT657564 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT659811 CASP16 caspase 16, pseudogene 2 2
MIRT660471 ARSK arylsulfatase family member K 2 2
MIRT661131 ZNF43 zinc finger protein 43 2 2
MIRT661193 MPPE1 metallophosphoesterase 1 2 2
MIRT661429 MANSC1 MANSC domain containing 1 2 2
MIRT661545 ZNF674 zinc finger protein 674 2 4
MIRT661669 ZNF623 zinc finger protein 623 2 2
MIRT661800 NUP85 nucleoporin 85 2 2
MIRT661853 ZNF766 zinc finger protein 766 2 2
MIRT662133 ZC3H8 zinc finger CCCH-type containing 8 2 2
MIRT662285 SLC29A4 solute carrier family 29 member 4 2 2
MIRT662705 C10orf111 chromosome 10 open reading frame 111 2 4
MIRT662823 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT662880 PCDHA6 protocadherin alpha 6 2 2
MIRT662999 TMEM59 transmembrane protein 59 2 2
MIRT663236 MPHOSPH8 M-phase phosphoprotein 8 2 2
MIRT663423 ZNF607 zinc finger protein 607 2 2
MIRT663696 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663832 AGBL5 ATP/GTP binding protein like 5 2 4
MIRT663858 MUC20 mucin 20, cell surface associated 2 2
MIRT664258 NMUR1 neuromedin U receptor 1 2 2
MIRT664842 HUS1 HUS1 checkpoint clamp component 2 2
MIRT664881 PRRG4 proline rich and Gla domain 4 2 2
MIRT664937 CARD6 caspase recruitment domain family member 6 2 4
MIRT665505 UTP15 UTP15, small subunit processome component 2 2
MIRT665640 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT665658 TRAF1 TNF receptor associated factor 1 2 2
MIRT665681 TNPO3 transportin 3 2 2
MIRT665934 TBC1D19 TBC1 domain family member 19 2 4
MIRT665995 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT666164 SNX27 sorting nexin family member 27 2 4
MIRT666364 SHOX short stature homeobox 2 2
MIRT666991 PDPN podoplanin 2 4
MIRT667179 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT667594 LIPC lipase C, hepatic type 2 2
MIRT667818 IRGQ immunity related GTPase Q 2 2
MIRT667845 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668571 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 4
MIRT669096 CDK19 cyclin dependent kinase 19 2 2
MIRT670062 ZNF783 zinc finger family member 783 2 2
MIRT670954 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT671180 ZNF891 zinc finger protein 891 2 2
MIRT673440 ZNF583 zinc finger protein 583 2 2
MIRT673941 ZNF500 zinc finger protein 500 2 2
MIRT674159 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674200 FUT2 fucosyltransferase 2 2 2
MIRT674677 PLCE1 phospholipase C epsilon 1 2 2
MIRT675232 MAK male germ cell associated kinase 2 2
MIRT676003 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT679836 GPR75 G protein-coupled receptor 75 2 2
MIRT680570 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT680750 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT680957 SLC15A1 solute carrier family 15 member 1 2 4
MIRT681201 ZNF638 zinc finger protein 638 2 2
MIRT681421 GTF3C6 general transcription factor IIIC subunit 6 2 2
MIRT681590 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT682026 AGXT2 alanine--glyoxylate aminotransferase 2 2 4
MIRT682340 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 4
MIRT682657 CASP8 caspase 8 2 2
MIRT682980 ABCA2 ATP binding cassette subfamily A member 2 2 2
MIRT683272 ZNF99 zinc finger protein 99 2 2
MIRT683349 SCARF1 scavenger receptor class F member 1 2 2
MIRT683447 ACOT2 acyl-CoA thioesterase 2 2 2
MIRT683586 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT683654 ZNF695 zinc finger protein 695 2 2
MIRT683733 EIF3L eukaryotic translation initiation factor 3 subunit L 2 2
MIRT683762 CPE carboxypeptidase E 2 2
MIRT683797 NOTO notochord homeobox 2 2
MIRT684453 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684510 C1orf174 chromosome 1 open reading frame 174 2 2
MIRT684979 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685003 CXorf56 chromosome X open reading frame 56 2 2
MIRT685106 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685123 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT685463 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT686021 UMPS uridine monophosphate synthetase 2 2
MIRT686551 TPM3 tropomyosin 3 2 2
MIRT686869 SLC25A32 solute carrier family 25 member 32 2 2
MIRT686962 SFT2D2 SFT2 domain containing 2 2 2
MIRT687278 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT688075 GLUL glutamate-ammonia ligase 2 2
MIRT688158 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT688574 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT688591 CYCS cytochrome c, somatic 2 2
MIRT689274 C5AR2 complement component 5a receptor 2 2 2
MIRT689427 CYB561 cytochrome b561 2 2
MIRT690043 C6orf141 chromosome 6 open reading frame 141 2 2
MIRT690214 C5orf45 MRN complex interacting protein 2 2
MIRT690259 CAMLG calcium modulating ligand 2 2
MIRT690319 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT690358 RPL37A ribosomal protein L37a 2 2
MIRT690519 ZNF566 zinc finger protein 566 2 2
MIRT690572 MICA MHC class I polypeptide-related sequence A 2 2
MIRT690707 WDR73 WD repeat domain 73 2 2
MIRT690862 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691150 APOL6 apolipoprotein L6 2 2
MIRT691279 CENPM centromere protein M 2 2
MIRT691754 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT691762 BCL2L15 BCL2 like 15 2 2
MIRT691775 SLC24A4 solute carrier family 24 member 4 2 2
MIRT692038 PAK1IP1 PAK1 interacting protein 1 2 2
MIRT692185 POLR1E RNA polymerase I subunit E 2 2
MIRT692756 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT692847 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT693064 AS3MT arsenite methyltransferase 2 2
MIRT693114 SCNM1 sodium channel modifier 1 2 2
MIRT693173 NPR1 natriuretic peptide receptor 1 2 2
MIRT693499 MOB3A MOB kinase activator 3A 2 2
MIRT693682 MXRA7 matrix remodeling associated 7 2 2
MIRT694066 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT694154 SLC36A2 solute carrier family 36 member 2 2 2
MIRT694251 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT694545 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694770 BVES blood vessel epicardial substance 2 2
MIRT695037 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT695265 CD209 CD209 molecule 2 2
MIRT695427 TCF23 transcription factor 23 2 2
MIRT695564 ZNF562 zinc finger protein 562 2 2
MIRT696357 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT696523 C3 complement C3 2 2
MIRT696611 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT696768 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT697066 PSMC4 proteasome 26S subunit, ATPase 4 2 2
MIRT697097 GPKOW G-patch domain and KOW motifs 2 2
MIRT697481 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT697622 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT697904 RPS27A ribosomal protein S27a 2 2
MIRT697956 TSPYL1 TSPY like 1 2 2
MIRT698366 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT698403 TM9SF3 transmembrane 9 superfamily member 3 2 2
MIRT698631 TES testin LIM domain protein 2 2
MIRT698963 SPAST spastin 2 2
MIRT699035 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699485 SLC10A6 solute carrier family 10 member 6 2 2
MIRT699579 SIKE1 suppressor of IKBKE 1 2 2
MIRT699594 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT699830 SCD stearoyl-CoA desaturase 2 2
MIRT700426 QDPR quinoid dihydropteridine reductase 2 2
MIRT700469 PURB purine rich element binding protein B 2 2
MIRT700863 PER2 period circadian clock 2 2 2
MIRT700943 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT701161 PACS2 phosphofurin acidic cluster sorting protein 2 2 2
MIRT701417 NHLRC2 NHL repeat containing 2 2 2
MIRT701468 NEK9 NIMA related kinase 9 2 2
MIRT701655 MYH9 myosin heavy chain 9 2 2
MIRT701693 MYADM myeloid associated differentiation marker 2 2
MIRT701769 MSL2 MSL complex subunit 2 2 2
MIRT701788 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT702784 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT703120 GPRC5A G protein-coupled receptor class C group 5 member A 2 2
MIRT703248 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT703265 GNL3L G protein nucleolar 3 like 2 2
MIRT703326 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT703648 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT703753 FAM118A family with sequence similarity 118 member A 2 2
MIRT703854 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT704315 DCUN1D5 defective in cullin neddylation 1 domain containing 5 2 2
MIRT704800 CDC73 cell division cycle 73 2 2
MIRT704941 CCDC120 coiled-coil domain containing 120 2 2
MIRT704975 CAV1 caveolin 1 2 2
MIRT705613 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 2
MIRT705672 ANKRD40 ankyrin repeat domain 40 2 2
MIRT706160 TFDP2 transcription factor Dp-2 2 2
MIRT706229 SYT15 synaptotagmin 15 2 2
MIRT706457 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT706555 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT707158 SMIM19 small integral membrane protein 19 2 2
MIRT710604 ZNF555 zinc finger protein 555 2 2
MIRT711709 IREB2 iron responsive element binding protein 2 2 2
MIRT711859 TRAF2 TNF receptor associated factor 2 2 2
MIRT713155 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT717108 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT721309 FAM58A cyclin Q 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4722 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4722 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4722 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4722-5p Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-4722-5p Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-4722-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4722-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4722-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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