miRTarBase - #MIRT453263


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pre-miRNA Information
pre-miRNA hsa-mir-1247   
Genomic Coordinates chr14: 101560287 - 101560422
Synonyms MIRN1247, hsa-mir-1247, MIR1247
Description Homo sapiens miR-1247 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1247-3p
Sequence 74| CCCCGGGAACGUCGAGACUGGAGC |97
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs765946490 1 dbSNP
rs1167774642 3 dbSNP
rs369874810 4 dbSNP
rs1295169065 5 dbSNP
rs1368557653 7 dbSNP
rs375254504 10 dbSNP
rs1049152389 16 dbSNP
rs774601647 21 dbSNP
rs1317190334 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PARP11   
Synonyms ARTD11, C12orf6, MIB006
Description poly(ADP-ribose) polymerase family member 11
Transcript NM_020367   
Expression
Putative miRNA Targets on PARP11
3'UTR of PARP11
(miRNA target sites are highlighted)		 
>PARP11|NM_020367|3'UTR
   1 TTTCACTTCCAAATCTCGGTGGTCAAGGAAGCTTTATTCTTTTTTGCAGGAAGGTTTGCTCTTCAGTCATCTAGCCACTA
  81 AATGTTAATTATCTGATACTTTTGAAACAGATATGAAAAAAAGTGGCCTCCATATAAAAAGACATACTGACTTCAAGGTT
 161 GGTTTTTGTTGTTTTGTTTTTGCCTGTTTCTTGTAGTCTTGTTTGTTAAAAGTTGATATCATTGATGTTTTAACACATAG
 241 GGGTGAAAGATACCATTCAAAATGGAATCAGCTGAGTCTCAACTAATGTGGTCATTGAGATCTTTAAAGTTTACGTGTGT
 321 GTTATCAGGATAAATGATTTTAGTTTAAATAGACTTATTCGTATAAATGTTGAAAAAAAATACAGACATAAATGTGTCCC
 401 TTTAGAGGAATTGATCCTTTGTAAATTGAATTCAGGTAGTAGTATCATCCACCAATCCATCTGTTGCTTTGTTGGTCTTC
 481 TGAAGGGGGGATTTAAAACTCTGAAACAGTCTGAGCACCTTGAGAGAAATCAGAAACAAGACAATTATTTGCAGTGCTGT
 561 CAAACAAGCCAGAAGGAGAAAATCAAGGTAGAATGCCCCACTTTCCAGTTGCCTTAGGATAGCAGGCTGCAGCCTCAGAC
 641 TTGATCCTGTCATTCTCCTCTGTCTCCCACATCTGAATTGATAATTGCTGCAAAATGTCATTAGCCTACACTTCATCCAT
 721 CAGGGCTCTTGGATTCTTACACCACGACTTGCTGTGCAAGGTGTTTATTGCATCTTCAAAGTGAAACTTTAAATTATTAT
 801 TCAAACATTTATTTTCCTTTTGTTTTAAAAAGAGTCCCTACAATGATCACTTCTAAGATTTTTTTTTACCTTCCCCTCTG
 881 CAGCACACACAGCTATTCAACAATGATTTCTAAAATTCATATTTCAAATTTGTATCTCTCCATTTTGAAACATTATAGAA
 961 AGCATGGGATGCTTGAGACAAATCTGGTTTCTCCTTTGAAGTAGCTGTTGACAACCTACTCTCTTGAAAAGTTAGATATA
1041 ATTCTTAATCATGTTTAGTGGAAATTTGTTTACCTGTTCCATCTGTTTTGCTGTTTCATTGTAAGGAAGATGAGAAGTGT
1121 TGGAACAGCTTCCCTCCCCTAAAGGTATTCTAGCAGAGGCGAGACAGCAACTTGGCGGGCATGTTGCATAGGAGTTAAGT
1201 ACCAGATGGGGAATTGCCCATGTGATGGTGAAGAGTCTCTCACATTGATTTTCTTCCTTTTCTCCTCTTCTCTCCTCCTT
1281 CTCTTCTCTCCTCTTTCTCTTCTCTTCTTTCTCTTCTCTTCTGTCTTCCTCTTCCTCTTCTCTTCCTCTCCTCTTCCTCT
1361 TTCTCTCTCTTCCTTTTTCTCTTCCTCTTTCTCTTTCTCTTTCTCTTCTCTTCTCTCTCTCTTCCTTCCTTCTTTCTTTC
1441 CTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCTTTCCCTCCCTCCCTCCCTCCCTCCTCCCTTTTTCTTTTTCTTT
1521 CTTTTTTTTTGGTTTGGCAGAGTCTTGCTCTGTTGCCCAGGCTGCAGTGCAGTGGTGTGATCTCGGCTCACTGCAACCTC
1601 CACCTCCCGGGTTCAAGCAATTCTCTTGCCTCAGCTTCTCCAGTTACTGGGACTACAGGTGCATACCACCATGCCCGGCT
1681 AATTTTTGTATTTTTAGTAGAGGCGGGGTTTTGTCATGTTGGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGATCCGC
1761 CTGCCTCAGCCTTCCAAAGTGCTGAGATTACAGGCATGAGCCGCTGTACCCGGCCTGATTTTCTATGATTCTGCCTTTAA
1841 AAGACAGCACGTATACCAAGCCTTTTTCAGAAAGCTTTTCTCTTAACTCCTTCTAATGCTGAATTTTCTCTCTATTATCC
1921 TCACCCAATTTTGGCTGAGAGTTAGTGTACACAATTTAACTTCTTAGAAAAATTCCAGTGTCTATGCTTATATTGCTCAC
2001 TTGAATCATTTGAATTAGAAAGGGATCTACAAATAATAAAAGCAAAGAGTGCAGACAGATTAGGGATAGTAATTCTTAAA
2081 GTGCCATCTATCCCAGATTTCCGTTATAGACCAGCATATGTGTAATTGTGCAGTGGGAGGTAAGTAGTACCCAGGACATT
2161 GCATGTACAATACTTTGAAACAAAGTGGCAACAAAGATTTCCTGGCTCAGGTATGCACCCCAGCTGCTGGTTTAGATGAA
2241 GTGCTGAGAATATTTAGAAAAAGCGCTTTAAAAAGCATCTAGAGATTATCATGAAAATAATTGGAGACAAAGTCACTAGG
2321 CTGCTTTGTGAGAGGCAGCATACCATGGCTCTAAACCCGTTCACAAAAAACAATGTTAGAGACATTAGGAATTCAGGTTT
2401 TGAAAATCTTTTTTTCGATTTATTTGTAATTTACATACCAAAAAACCACATTAAAATAGTCCTCCCTTCAACATGGCTAT
2481 CTTTTTTCAAGTTTTATATGCATAGCTCTCTCAGCACTTGAATGGAAAAACTGTTACAGCATTTGGGAGTTGTTTTTCTT
2561 TTAGACTTTGCAGATCTTATCTCAAGGTGACTAGGAACCCAGAGCTAAGTATCTGTGAGGCAATCTCTGCGAACGCTGAA
2641 CTTACCTAGTTGGTTTCTATGAAATATGTAGAATGCACTGCAGTAGCCATTGTAAGAAGGTACTATACCGGTTTTTTGGG
2721 GCTTGTTGTTGTTGTTTGGTCTGAGAATGTACTGCCAACCCCTCTTTTATAAGAGAGAACTGATTTTGATACATATTTTA
2801 AAATATGATAGTACAGAGTTAATGGATGTTAAAATTTTATTTCTTTGTTTTGGTAAGTAGATTAAATCGAGAATCATATA
2881 ATCAGTACATTTGAGAATTATATAACCAGTATATAATAATACTGGACACAACCATTTGCCATCTTTTCCTGTTATCATCC
2961 CATAGAGTGGGTGGGGAGAATGAATAGACATAAACCTAGAATAATGATAAATGGTTTTTAAAACTCTATATTGAATACAT
3041 TCCAGCTGATAATGACTTTTCTTTTTCACCTTGGTGATATCAGCCTCAGGGTAAAAAAAAAAGTTTCATAAATCTTTTAG
3121 TTATAAACAGGAAAGTTTTATATTAGTGTGTCATTTCATTTCTAGACTGTTGATGGTGATGATGATAAAGAATTTGGAGC
3201 CAATTTTGATATATGAATGTATTGCTTTTACATGTGATGATTAAAGCTCTCCATTAGCAGTT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgAGGUCAGAGCUGCAAGGGCCCc 5'
            | ||  ||| ||  ||||||| 
Target 5' acTGCAACCTCCAC-CTCCCGGGt 3'
 1590 - 1612 157.00 -21.70
2 
miRNA  3' cgaGGUC--AGAGCUGCAAGGGCCCc 5'
             :|||  |||| | ||| |:||| 
Target 5' gccTCAGCTTCTCCA-GTTACTGGGa 3'
 1628 - 1652 122.00 -17.80
3 
miRNA  3' cgAGGUCAGAGCUGCAAGGGCCcc 5'
            | ||||  :| :| ||:|||  
Target 5' agTGCAGTGGTG-TGATCTCGGct 3'
 1566 - 1588 121.00 -15.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30707148 2 COSMIC
COSN30506928 18 COSMIC
COSN31522058 36 COSMIC
COSN30508702 54 COSMIC
COSN30180254 58 COSMIC
COSN26423607 60 COSMIC
COSN30157158 64 COSMIC
COSN30104930 105 COSMIC
COSN20077577 169 COSMIC
COSN30127444 220 COSMIC
COSN32076348 224 COSMIC
COSN30363420 308 COSMIC
COSN31600354 382 COSMIC
COSN29939244 503 COSMIC
COSN29593813 859 COSMIC
COSN22536181 987 COSMIC
COSN22143505 1007 COSMIC
COSN7369026 1086 COSMIC
COSN1571393 1142 COSMIC
COSN24009346 1208 COSMIC
COSN4729535 1216 COSMIC
COSN16704515 1303 COSMIC
COSN20077680 1437 COSMIC
COSN9558990 1453 COSMIC
COSN16239262 1469 COSMIC
COSN23924151 1482 COSMIC
COSN32087519 1538 COSMIC
COSN24330425 1709 COSMIC
COSN9083428 1781 COSMIC
COSN16839370 1818 COSMIC
COSN5942219 1855 COSMIC
COSN1571392 1893 COSMIC
COSN1571391 1917 COSMIC
COSN22794813 2052 COSMIC
COSN20109083 2566 COSMIC
COSN22807121 2694 COSMIC
COSN20109081 2765 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1020979240 4 dbSNP
rs1045994485 6 dbSNP
rs372013391 8 dbSNP
rs1202881262 14 dbSNP
rs376688161 17 dbSNP
rs372123433 18 dbSNP
rs764323931 23 dbSNP
rs1181394671 25 dbSNP
rs1319070450 29 dbSNP
rs1242651337 31 dbSNP
rs760832367 33 dbSNP
rs1404247760 34 dbSNP
rs1289899667 35 dbSNP
rs1175935375 38 dbSNP
rs530122146 39 dbSNP
rs1470401648 40 dbSNP
rs1314733040 42 dbSNP
rs753294512 42 dbSNP
rs561096087 46 dbSNP
rs759839723 50 dbSNP
rs925784430 54 dbSNP
rs186432451 59 dbSNP
rs1281787574 71 dbSNP
rs1403383213 75 dbSNP
rs1170073838 82 dbSNP
rs1326463181 84 dbSNP
rs1351787318 88 dbSNP
rs1409977527 91 dbSNP
rs145096701 102 dbSNP
rs1343620214 104 dbSNP
rs964584361 105 dbSNP
rs1420737828 108 dbSNP
rs1235360977 111 dbSNP
rs1054648541 113 dbSNP
rs1006603747 114 dbSNP
rs1161813092 115 dbSNP
rs1018790471 116 dbSNP
rs889545559 118 dbSNP
rs3214323 123 dbSNP
rs397818975 123 dbSNP
rs768260458 123 dbSNP
rs1008835736 124 dbSNP
rs950397814 128 dbSNP
rs1182029615 132 dbSNP
rs918490638 133 dbSNP
rs1458829294 134 dbSNP
rs1025988708 144 dbSNP
rs1359705180 145 dbSNP
rs1235769626 153 dbSNP
rs1201652247 154 dbSNP
rs1378515912 155 dbSNP
rs1475326357 159 dbSNP
rs1372069940 161 dbSNP
rs1429804721 162 dbSNP
rs1301940915 163 dbSNP
rs1363207844 166 dbSNP
rs1388374024 168 dbSNP
rs941302635 171 dbSNP
rs994987852 176 dbSNP
rs1325623542 182 dbSNP
rs565225831 186 dbSNP
rs1295636188 196 dbSNP
rs1344640486 199 dbSNP
rs1038529527 203 dbSNP
rs1468859274 208 dbSNP
rs1292018174 216 dbSNP
rs1001674445 219 dbSNP
rs1487554485 237 dbSNP
rs990671597 240 dbSNP
rs183780981 242 dbSNP
rs1046365981 250 dbSNP
rs1446755960 255 dbSNP
rs1279957501 278 dbSNP
rs1241394118 280 dbSNP
rs1374958718 284 dbSNP
rs766444832 287 dbSNP
rs1330755808 290 dbSNP
rs1441809928 293 dbSNP
rs576191476 302 dbSNP
rs1322185398 314 dbSNP
rs564700843 315 dbSNP
rs542331465 324 dbSNP
rs1384211954 325 dbSNP
rs1380287865 333 dbSNP
rs573661609 334 dbSNP
rs1322241805 337 dbSNP
rs891781194 353 dbSNP
rs1053162684 358 dbSNP
rs191518200 360 dbSNP
rs1441087223 368 dbSNP
rs533775103 370 dbSNP
rs578033029 372 dbSNP
rs1020295934 381 dbSNP
rs971398519 381 dbSNP
rs1465638729 383 dbSNP
rs974813183 383 dbSNP
rs1182578146 389 dbSNP
rs763148637 392 dbSNP
rs943184347 394 dbSNP
rs1248358546 403 dbSNP
rs911734966 421 dbSNP
rs1007095167 423 dbSNP
rs1451489564 426 dbSNP
rs1450990319 430 dbSNP
rs558037652 436 dbSNP
rs987762079 438 dbSNP
rs1451731081 441 dbSNP
rs1336285399 444 dbSNP
rs950697416 447 dbSNP
rs538047204 453 dbSNP
rs1398026344 463 dbSNP
rs1050856218 469 dbSNP
rs997840456 470 dbSNP
rs896788840 491 dbSNP
rs1163379574 498 dbSNP
rs1270643693 500 dbSNP
rs1203480075 503 dbSNP
rs1330242180 503 dbSNP
rs1308861301 504 dbSNP
rs1253865033 506 dbSNP
rs749243412 507 dbSNP
rs1036720866 508 dbSNP
rs1235075874 515 dbSNP
rs569038824 530 dbSNP
rs909808026 531 dbSNP
rs1054877735 536 dbSNP
rs1173632529 539 dbSNP
rs1273177034 543 dbSNP
rs780194925 544 dbSNP
rs1303654392 559 dbSNP
rs1372690244 568 dbSNP
rs1408155514 568 dbSNP
rs74703324 570 dbSNP
rs1351702908 576 dbSNP
rs1223465040 582 dbSNP
rs1033405063 583 dbSNP
rs1320691287 599 dbSNP
rs1418319069 600 dbSNP
rs1001955827 604 dbSNP
rs1481768210 609 dbSNP
rs1206740235 612 dbSNP
rs971472118 618 dbSNP
rs71534270 629 dbSNP
rs1434986238 634 dbSNP
rs1189401264 637 dbSNP
rs988833411 643 dbSNP
rs1426930308 646 dbSNP
rs1433612712 648 dbSNP
rs186652380 657 dbSNP
rs1370233390 661 dbSNP
rs1426603888 661 dbSNP
rs1024510601 666 dbSNP
rs1014916644 670 dbSNP
rs892068454 673 dbSNP
rs1053514853 684 dbSNP
rs573042467 693 dbSNP
rs527672838 697 dbSNP
rs116668113 702 dbSNP
rs551626829 710 dbSNP
rs997914173 712 dbSNP
rs1294379414 716 dbSNP
rs896908271 726 dbSNP
rs1015641652 735 dbSNP
rs1274642506 738 dbSNP
rs1490046617 740 dbSNP
rs181099684 740 dbSNP
rs1005252469 744 dbSNP
rs1285080792 745 dbSNP
rs987361672 746 dbSNP
rs76530375 749 dbSNP
rs1388117206 752 dbSNP
rs1054990323 756 dbSNP
rs562970612 759 dbSNP
rs973335999 761 dbSNP
rs781161198 767 dbSNP
rs1280704664 770 dbSNP
rs1033353011 772 dbSNP
rs1437833622 773 dbSNP
rs76536944 781 dbSNP
rs980508130 807 dbSNP
rs1340255211 832 dbSNP
rs142803197 838 dbSNP
rs148495129 843 dbSNP
rs1358097064 845 dbSNP
rs913347799 860 dbSNP
rs1014451776 867 dbSNP
rs936038284 868 dbSNP
rs989213322 868 dbSNP
rs75966484 872 dbSNP
rs147876615 876 dbSNP
rs1245897267 886 dbSNP
rs1466099148 891 dbSNP
rs777189680 892 dbSNP
rs1190741472 900 dbSNP
rs1173324852 903 dbSNP
rs1472496529 904 dbSNP
rs1161484522 921 dbSNP
rs1416090611 929 dbSNP
rs1406390555 932 dbSNP
rs1159087762 940 dbSNP
rs1386889745 942 dbSNP
rs1413457112 947 dbSNP
rs1031900704 958 dbSNP
rs1000408968 962 dbSNP
rs561017256 964 dbSNP
rs1445391245 965 dbSNP
rs1039047217 967 dbSNP
rs1379271154 977 dbSNP
rs80345845 979 dbSNP
rs577672539 997 dbSNP
rs768911034 998 dbSNP
rs1330947845 1006 dbSNP
rs890568262 1007 dbSNP
rs1262303106 1010 dbSNP
rs1442016402 1012 dbSNP
rs1262129663 1014 dbSNP
rs1052021317 1018 dbSNP
rs1188394082 1020 dbSNP
rs747480896 1021 dbSNP
rs1473198512 1032 dbSNP
rs1484358168 1035 dbSNP
rs929126950 1039 dbSNP
rs1236005198 1055 dbSNP
rs1209479932 1056 dbSNP
rs1459139455 1058 dbSNP
rs1308195845 1064 dbSNP
rs1160305055 1066 dbSNP
rs1260115843 1067 dbSNP
rs1335796710 1070 dbSNP
rs763640495 1079 dbSNP
rs1317857943 1081 dbSNP
rs79208366 1085 dbSNP
rs1286348590 1093 dbSNP
rs1015384258 1096 dbSNP
rs1005613155 1097 dbSNP
rs1228961922 1101 dbSNP
rs764170775 1109 dbSNP
rs1342628490 1123 dbSNP
rs926274114 1124 dbSNP
rs980455529 1134 dbSNP
rs970868199 1135 dbSNP
rs1281070357 1136 dbSNP
rs1486020252 1152 dbSNP
rs1230442220 1154 dbSNP
rs917645094 1160 dbSNP
rs1473836513 1161 dbSNP
rs538110371 1171 dbSNP
rs1446871949 1175 dbSNP
rs140596160 1176 dbSNP
rs748840668 1177 dbSNP
rs1173965092 1180 dbSNP
rs1402522553 1197 dbSNP
rs1031810730 1199 dbSNP
rs906467783 1206 dbSNP
rs1046205554 1207 dbSNP
rs1410295655 1210 dbSNP
rs1322875226 1227 dbSNP
rs1463937448 1236 dbSNP
rs11612988 1237 dbSNP
rs968984301 1239 dbSNP
rs1276803004 1244 dbSNP
rs1348813684 1250 dbSNP
rs1017541709 1260 dbSNP
rs147200625 1262 dbSNP
rs1272488660 1265 dbSNP
rs890466026 1268 dbSNP
rs1484086587 1269 dbSNP
rs1425387144 1272 dbSNP
rs1051815848 1280 dbSNP
rs1267350872 1281 dbSNP
rs1053235853 1283 dbSNP
rs993995339 1284 dbSNP
rs897649863 1286 dbSNP
rs1181457063 1288 dbSNP
rs936099452 1289 dbSNP
rs1481097274 1290 dbSNP
rs1017986695 1294 dbSNP
rs575688066 1294 dbSNP
rs1429908012 1295 dbSNP
rs985463837 1296 dbSNP
rs1240044629 1299 dbSNP
rs1196839655 1301 dbSNP
rs1008318726 1306 dbSNP
rs1364202484 1309 dbSNP
rs1274402892 1316 dbSNP
rs189748062 1317 dbSNP
rs1228295320 1323 dbSNP
rs1295752738 1323 dbSNP
rs1344406004 1323 dbSNP
rs1265350875 1325 dbSNP
rs922883802 1328 dbSNP
rs1247396876 1332 dbSNP
rs58675636 1335 dbSNP
rs961591826 1336 dbSNP
rs139643894 1341 dbSNP
rs765782221 1347 dbSNP
rs1186271677 1350 dbSNP
rs1227326422 1351 dbSNP
rs1428567920 1361 dbSNP
rs1163399369 1362 dbSNP
rs983863664 1363 dbSNP
rs533950061 1364 dbSNP
rs1265101275 1365 dbSNP
rs1310804362 1371 dbSNP
rs748542647 1371 dbSNP
rs1444014399 1372 dbSNP
rs1318752299 1373 dbSNP
rs1455506579 1373 dbSNP
rs1399432136 1375 dbSNP
rs149503127 1376 dbSNP
rs908275331 1379 dbSNP
rs1338789345 1380 dbSNP
rs1247608863 1381 dbSNP
rs926553181 1384 dbSNP
rs1328870598 1387 dbSNP
rs144584425 1389 dbSNP
rs771668498 1389 dbSNP
rs1270440579 1390 dbSNP
rs1347857594 1390 dbSNP
rs386375431 1390 dbSNP
rs1163828562 1395 dbSNP
rs1180933626 1395 dbSNP
rs1253394169 1395 dbSNP
rs1425102001 1396 dbSNP
rs1188566011 1399 dbSNP
rs1001858798 1401 dbSNP
rs1471476299 1401 dbSNP
rs1382473034 1402 dbSNP
rs1176828736 1403 dbSNP
rs1439203315 1404 dbSNP
rs200307166 1407 dbSNP
rs11283159 1408 dbSNP
rs1161045536 1408 dbSNP
rs372072975 1408 dbSNP
rs753791259 1408 dbSNP
rs754300764 1408 dbSNP
rs773955924 1408 dbSNP
rs970614287 1408 dbSNP
rs1024869757 1411 dbSNP
rs1009800369 1413 dbSNP
rs1211041950 1413 dbSNP
rs1250457949 1413 dbSNP
rs1253950263 1413 dbSNP
rs1483929745 1413 dbSNP
rs10687780 1417 dbSNP
rs202176088 1417 dbSNP
rs377332040 1417 dbSNP
rs1253735751 1419 dbSNP
rs1432450366 1421 dbSNP
rs892268726 1421 dbSNP
rs1054049422 1423 dbSNP
rs200174142 1423 dbSNP
rs57062061 1423 dbSNP
rs1487799418 1424 dbSNP
rs57860326 1424 dbSNP
rs1441148732 1428 dbSNP
rs868411198 1429 dbSNP
rs57460078 1433 dbSNP
rs949055200 1436 dbSNP
rs866648804 1437 dbSNP
rs1217038245 1438 dbSNP
rs1298711152 1440 dbSNP
rs1234612515 1441 dbSNP
rs1353953922 1441 dbSNP
rs866289418 1441 dbSNP
rs59300625 1442 dbSNP
rs1481819380 1443 dbSNP
rs1233425811 1444 dbSNP
rs1287780365 1444 dbSNP
rs7137256 1445 dbSNP
rs1237287915 1447 dbSNP
rs57172968 1447 dbSNP
rs1375469188 1448 dbSNP
rs1269235597 1449 dbSNP
rs7137255 1449 dbSNP
rs1174513917 1450 dbSNP
rs1388390759 1453 dbSNP
rs1389620032 1453 dbSNP
rs185225123 1453 dbSNP
rs1173129141 1457 dbSNP
rs968928983 1457 dbSNP
rs1365417216 1458 dbSNP
rs1017784283 1461 dbSNP
rs1292728523 1465 dbSNP
rs1420142700 1469 dbSNP
rs759864572 1470 dbSNP
rs201254913 1473 dbSNP
rs776931096 1474 dbSNP
rs1362653499 1475 dbSNP
rs1157037981 1476 dbSNP
rs1219284693 1477 dbSNP
rs1230038252 1477 dbSNP
rs1273120982 1477 dbSNP
rs1319444846 1477 dbSNP
rs1321001631 1477 dbSNP
rs1468795983 1477 dbSNP
rs201143468 1477 dbSNP
rs71061135 1477 dbSNP
rs7308661 1477 dbSNP
rs202091846 1478 dbSNP
rs749183855 1478 dbSNP
rs767675997 1478 dbSNP
rs1419348366 1479 dbSNP
rs1432492313 1479 dbSNP
rs1270203153 1481 dbSNP
rs146383802 1481 dbSNP
rs147407807 1482 dbSNP
rs1201097352 1483 dbSNP
rs1431939692 1484 dbSNP
rs1292026829 1485 dbSNP
rs879370249 1485 dbSNP
rs1218220876 1486 dbSNP
rs1251388851 1486 dbSNP
rs1266036013 1486 dbSNP
rs1463681105 1486 dbSNP
rs1472547109 1486 dbSNP
rs1180590186 1490 dbSNP
rs1221210960 1490 dbSNP
rs1420713731 1491 dbSNP
rs1475832865 1495 dbSNP
rs1158833032 1499 dbSNP
rs1331163628 1502 dbSNP
rs1386909530 1502 dbSNP
rs202053396 1502 dbSNP
rs747954256 1502 dbSNP
rs1445230665 1503 dbSNP
rs775358304 1504 dbSNP
rs1355959568 1506 dbSNP
rs1388056360 1507 dbSNP
rs1227742692 1511 dbSNP
rs1489499903 1516 dbSNP
rs1352591286 1517 dbSNP
rs1207112787 1521 dbSNP
rs1285266901 1523 dbSNP
rs1284365121 1525 dbSNP
rs904617988 1526 dbSNP
rs1182104248 1531 dbSNP
rs1259732865 1531 dbSNP
rs1486245091 1531 dbSNP
rs1292645406 1532 dbSNP
rs1410193655 1537 dbSNP
rs551342241 1550 dbSNP
rs1158760090 1555 dbSNP
rs771212735 1584 dbSNP
rs1352548986 1585 dbSNP
rs1375526596 1588 dbSNP
rs1409079187 1589 dbSNP
rs1306169959 1594 dbSNP
rs1256009389 1596 dbSNP
rs1239562243 1598 dbSNP
rs761459663 1599 dbSNP
rs1344531540 1602 dbSNP
rs1232370835 1608 dbSNP
rs138547609 1609 dbSNP
rs1348760300 1611 dbSNP
rs12424076 1620 dbSNP
rs1250302109 1623 dbSNP
rs1439900963 1630 dbSNP
rs180822067 1632 dbSNP
rs1400568055 1638 dbSNP
rs1246522394 1641 dbSNP
rs1476799484 1642 dbSNP
rs1175143964 1643 dbSNP
rs748796233 1650 dbSNP
rs1167946278 1655 dbSNP
rs1041329171 1662 dbSNP
rs1166615270 1663 dbSNP
rs1398482281 1670 dbSNP
rs1391925837 1674 dbSNP
rs529442847 1676 dbSNP
rs1329144952 1690 dbSNP
rs905043188 1694 dbSNP
rs1296124726 1696 dbSNP
rs1044961955 1697 dbSNP
rs1227833331 1699 dbSNP
rs560715948 1704 dbSNP
rs560000835 1705 dbSNP
rs1021741556 1709 dbSNP
rs540295253 1718 dbSNP
rs532978726 1722 dbSNP
rs564097052 1729 dbSNP
rs926412018 1743 dbSNP
rs935079285 1750 dbSNP
rs1253290381 1751 dbSNP
rs925062795 1752 dbSNP
rs979164229 1759 dbSNP
rs1186078972 1765 dbSNP
rs1374297173 1766 dbSNP
rs1462378410 1767 dbSNP
rs754761526 1779 dbSNP
rs544210410 1782 dbSNP
rs553478324 1786 dbSNP
rs189427708 1802 dbSNP
rs1371942056 1803 dbSNP
rs555630252 1807 dbSNP
rs1009464811 1811 dbSNP
rs1328291179 1812 dbSNP
rs541659500 1825 dbSNP
rs986391029 1832 dbSNP
rs1256494235 1834 dbSNP
rs1284198128 1835 dbSNP
rs1333118812 1845 dbSNP
rs1215890019 1847 dbSNP
rs1274232055 1849 dbSNP
rs375159867 1850 dbSNP
rs955168991 1851 dbSNP
rs1263197753 1853 dbSNP
rs1030313957 1854 dbSNP
rs1415649325 1857 dbSNP
rs1032143616 1859 dbSNP
rs572949722 1861 dbSNP
rs1287398177 1863 dbSNP
rs1481964786 1869 dbSNP
rs1254922801 1881 dbSNP
rs962049890 1887 dbSNP
rs1354067955 1894 dbSNP
rs1235682868 1895 dbSNP
rs553999018 1898 dbSNP
rs1016331288 1912 dbSNP
rs1195712442 1922 dbSNP
rs1219100705 1924 dbSNP
rs1262162154 1928 dbSNP
rs1006311096 1934 dbSNP
rs1049863152 1935 dbSNP
rs1254821844 1936 dbSNP
rs904994041 1940 dbSNP
rs1217844223 1945 dbSNP
rs1410940751 1948 dbSNP
rs1417156744 1950 dbSNP
rs1023925765 1953 dbSNP
rs769333662 1953 dbSNP
rs996838142 1954 dbSNP
rs901146813 1966 dbSNP
rs1041444294 1973 dbSNP
rs1373719869 1982 dbSNP
rs534895061 1984 dbSNP
rs745826050 1987 dbSNP
rs1350219710 1990 dbSNP
rs896420077 1992 dbSNP
rs908820953 1995 dbSNP
rs1390074484 1996 dbSNP
rs567881494 1999 dbSNP
rs1232083915 2005 dbSNP
rs1277499448 2012 dbSNP
rs1349498854 2014 dbSNP
rs1211505916 2015 dbSNP
rs1332142065 2024 dbSNP
rs1251044966 2026 dbSNP
rs142272418 2043 dbSNP
rs903548823 2044 dbSNP
rs1178682905 2050 dbSNP
rs184638533 2051 dbSNP
rs1419830661 2058 dbSNP
rs747252921 2066 dbSNP
rs1436703334 2068 dbSNP
rs1170395666 2069 dbSNP
rs910717098 2072 dbSNP
rs1354412356 2075 dbSNP
rs1460947770 2081 dbSNP
rs986726981 2083 dbSNP
rs557773623 2086 dbSNP
rs1374525543 2092 dbSNP
rs923486906 2095 dbSNP
rs972359124 2102 dbSNP
rs961998300 2103 dbSNP
rs1300894012 2106 dbSNP
rs917553801 2107 dbSNP
rs139000351 2111 dbSNP
rs1189130090 2116 dbSNP
rs11062839 2127 dbSNP
rs1305625267 2128 dbSNP
rs984867492 2132 dbSNP
rs549613450 2133 dbSNP
rs1241908518 2147 dbSNP
rs1198798753 2150 dbSNP
rs1032713524 2155 dbSNP
rs143349246 2157 dbSNP
rs1256132624 2158 dbSNP
rs979241440 2164 dbSNP
rs149180300 2168 dbSNP
rs1356740425 2170 dbSNP
rs1285758535 2181 dbSNP
rs1194297879 2188 dbSNP
rs547193705 2191 dbSNP
rs1340101987 2195 dbSNP
rs1355480091 2201 dbSNP
rs1461289756 2205 dbSNP
rs1323456195 2211 dbSNP
rs1023451702 2216 dbSNP
rs1441184446 2225 dbSNP
rs1269017861 2232 dbSNP
rs1359321706 2233 dbSNP
rs1216247351 2236 dbSNP
rs1310078110 2244 dbSNP
rs1013868246 2252 dbSNP
rs547051507 2253 dbSNP
rs960585532 2257 dbSNP
rs901264783 2264 dbSNP
rs533093887 2265 dbSNP
rs145247853 2268 dbSNP
rs999402188 2275 dbSNP
rs1474506231 2279 dbSNP
rs1331311523 2284 dbSNP
rs1019603134 2285 dbSNP
rs1475181945 2301 dbSNP
rs903519662 2303 dbSNP
rs1420486389 2307 dbSNP
rs544270044 2311 dbSNP
rs1317278264 2344 dbSNP
rs887347106 2345 dbSNP
rs776306112 2348 dbSNP
rs1471601714 2351 dbSNP
rs530476298 2358 dbSNP
rs1049148837 2359 dbSNP
rs1354695054 2363 dbSNP
rs561842246 2367 dbSNP
rs1335302273 2371 dbSNP
rs118014543 2373 dbSNP
rs931576588 2379 dbSNP
rs1445335350 2387 dbSNP
rs1217984022 2389 dbSNP
rs1242810370 2397 dbSNP
rs1186494762 2408 dbSNP
rs1420462793 2409 dbSNP
rs1475759876 2416 dbSNP
rs182025699 2416 dbSNP
rs1860617 2417 dbSNP
rs1374337446 2418 dbSNP
rs1412845297 2420 dbSNP
rs755419874 2426 dbSNP
rs545586573 2428 dbSNP
rs1355821147 2435 dbSNP
rs1441276656 2445 dbSNP
rs1180940264 2446 dbSNP
rs923464432 2448 dbSNP
rs1036581319 2454 dbSNP
rs987823922 2461 dbSNP
rs1347326194 2465 dbSNP
rs940957680 2473 dbSNP
rs909211240 2480 dbSNP
rs1209311593 2483 dbSNP
rs1260289513 2488 dbSNP
rs754347469 2499 dbSNP
rs1452122677 2502 dbSNP
rs766759756 2517 dbSNP
rs984815537 2529 dbSNP
rs377153218 2531 dbSNP
rs1393952126 2537 dbSNP
rs145232231 2537 dbSNP
rs1432373470 2540 dbSNP
rs373298041 2565 dbSNP
rs138698498 2566 dbSNP
rs370120924 2566 dbSNP
rs71061134 2567 dbSNP
rs76847394 2567 dbSNP
rs925211433 2574 dbSNP
rs1409338607 2590 dbSNP
rs1242371369 2592 dbSNP
rs1337367981 2593 dbSNP
rs979316411 2598 dbSNP
rs953294542 2610 dbSNP
rs1370304722 2628 dbSNP
rs1308637642 2631 dbSNP
rs916623482 2632 dbSNP
rs1195745434 2634 dbSNP
rs975946461 2635 dbSNP
rs1333396074 2636 dbSNP
rs371309253 2649 dbSNP
rs1182044658 2652 dbSNP
rs1439988992 2652 dbSNP
rs1252044918 2653 dbSNP
rs965488640 2657 dbSNP
rs1194923125 2659 dbSNP
rs1395167857 2666 dbSNP
rs1475011573 2677 dbSNP
rs550174023 2682 dbSNP
rs1398318452 2689 dbSNP
rs774029649 2694 dbSNP
rs1410368448 2699 dbSNP
rs1405190019 2705 dbSNP
rs960784341 2709 dbSNP
rs1393968773 2710 dbSNP
rs1438987786 2710 dbSNP
rs1004201769 2711 dbSNP
rs887076957 2712 dbSNP
rs1227339420 2724 dbSNP
rs1026959128 2725 dbSNP
rs1341883825 2737 dbSNP
rs76011121 2737 dbSNP
rs1272983869 2743 dbSNP
rs1466811967 2748 dbSNP
rs571008786 2757 dbSNP
rs905461621 2762 dbSNP
rs1267429871 2763 dbSNP
rs1445954849 2768 dbSNP
rs3079895 2769 dbSNP
rs1374672852 2773 dbSNP
rs1198121325 2782 dbSNP
rs1377885267 2789 dbSNP
rs879193903 2794 dbSNP
rs764475687 2806 dbSNP
rs1478313561 2808 dbSNP
rs967961015 2811 dbSNP
rs700481 2814 dbSNP
rs769073474 2819 dbSNP
rs1381771361 2826 dbSNP
rs769446842 2827 dbSNP
rs1328670870 2831 dbSNP
rs1196455816 2843 dbSNP
rs1006483861 2845 dbSNP
rs935110102 2851 dbSNP
rs1265709583 2861 dbSNP
rs889475398 2868 dbSNP
rs745738053 2873 dbSNP
rs997950840 2875 dbSNP
rs1187204933 2889 dbSNP
rs1255132780 2893 dbSNP
rs776778536 2908 dbSNP
rs1167150471 2911 dbSNP
rs537860505 2912 dbSNP
rs1369222281 2919 dbSNP
rs532046029 2921 dbSNP
rs921883307 2924 dbSNP
rs1351782581 2932 dbSNP
rs1453364128 2943 dbSNP
rs975895626 2944 dbSNP
rs1387253131 2945 dbSNP
rs1401131670 2957 dbSNP
rs1036573391 2959 dbSNP
rs1219944196 2971 dbSNP
rs113462095 2974 dbSNP
rs940905963 2986 dbSNP
rs909495712 2987 dbSNP
rs758799 2989 dbSNP
rs948026140 3006 dbSNP
rs916588408 3008 dbSNP
rs1236447761 3021 dbSNP
rs1261956359 3023 dbSNP
rs1341467344 3028 dbSNP
rs1300448115 3029 dbSNP
rs992618696 3030 dbSNP
rs1401392787 3036 dbSNP
rs939486536 3045 dbSNP
rs1278167246 3053 dbSNP
rs189890309 3058 dbSNP
rs1486625105 3062 dbSNP
rs746830260 3069 dbSNP
rs1249566107 3074 dbSNP
rs923751336 3076 dbSNP
rs772523908 3080 dbSNP
rs1180006855 3085 dbSNP
rs1382245374 3091 dbSNP
rs1235033337 3100 dbSNP
rs201709805 3101 dbSNP
rs867762763 3101 dbSNP
rs1173111371 3103 dbSNP
rs1437127783 3103 dbSNP
rs34818389 3103 dbSNP
rs397849999 3103 dbSNP
rs967868140 3106 dbSNP
rs1026909960 3110 dbSNP
rs1373129980 3111 dbSNP
rs184904641 3125 dbSNP
rs985344033 3133 dbSNP
rs969612489 3134 dbSNP
rs953807539 3135 dbSNP
rs1029362354 3141 dbSNP
rs1376965497 3144 dbSNP
rs1023868034 3155 dbSNP
rs1480075135 3166 dbSNP
rs1349886617 3175 dbSNP
rs200958133 3176 dbSNP
rs371527388 3176 dbSNP
rs1195657714 3182 dbSNP
rs1479576732 3184 dbSNP
rs896618843 3211 dbSNP
rs1487421539 3213 dbSNP
rs1241792495 3214 dbSNP
rs536173387 3217 dbSNP
rs896928080 3225 dbSNP
rs778025946 3226 dbSNP
rs1005028618 3232 dbSNP
rs542529768 3232 dbSNP
rs887964612 3234 dbSNP
rs1435410364 3237 dbSNP
rs1177508084 3238 dbSNP
rs1049305092 3242 dbSNP
rs3168623 3251 dbSNP
rs1460833282 3254 dbSNP
rs895131432 3257 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgaggucagagcugcaAGGGCCCc 5'
                          ||||||| 
Target 5' --------------ccUCCCGGGu 3'
 		1 - 10
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000427057.2 | 3UTR | CCUCCCGGGUUCAAGCAAUUCUCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
228 hsa-miR-1247-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT107246 PTGES2 prostaglandin E synthase 2 2 2
MIRT118004 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 6
MIRT345983 BIRC5 baculoviral IAP repeat containing 5 2 4
MIRT369967 ZNF264 zinc finger protein 264 2 2
MIRT451350 ZNF573 zinc finger protein 573 2 4
MIRT451367 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451450 ZNF556 zinc finger protein 556 2 4
MIRT451766 ZNF611 zinc finger protein 611 2 6
MIRT452065 ZNF585B zinc finger protein 585B 2 8
MIRT452346 TG thyroglobulin 2 2
MIRT452519 TFDP2 transcription factor Dp-2 2 6
MIRT452631 FAM162A family with sequence similarity 162 member A 2 2
MIRT452896 PSD4 pleckstrin and Sec7 domain containing 4 2 4
MIRT453263 PARP11 poly(ADP-ribose) polymerase family member 11 2 2
MIRT453567 RDH13 retinol dehydrogenase 13 2 2
MIRT453911 GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 2 4
MIRT454576 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT454859 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455094 NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2 2
MIRT455790 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT455932 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT456213 LIX1L limb and CNS expressed 1 like 2 4
MIRT456238 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2 6
MIRT456279 HRNR hornerin 2 2
MIRT456665 TIFA TRAF interacting protein with forkhead associated domain 2 2
MIRT457088 XPNPEP3 X-prolyl aminopeptidase 3 2 2
MIRT457322 DUSP19 dual specificity phosphatase 19 2 2
MIRT457695 ZNF587 zinc finger protein 587 2 4
MIRT458160 LYRM4 LYR motif containing 4 2 6
MIRT458465 SNX22 sorting nexin 22 2 8
MIRT458504 MARVELD2 MARVEL domain containing 2 2 2
MIRT458514 GSG2 histone H3 associated protein kinase 2 10
MIRT458645 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT458823 ZNF843 zinc finger protein 843 2 4
MIRT459156 NARF nuclear prelamin A recognition factor 2 2
MIRT459182 HSPA6 heat shock protein family A (Hsp70) member 6 2 4
MIRT459374 MPLKIP M-phase specific PLK1 interacting protein 2 6
MIRT459552 BTD biotinidase 2 2
MIRT459756 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT459860 SVOP SV2 related protein 2 8
MIRT460020 DTX3L deltex E3 ubiquitin ligase 3L 2 6
MIRT460233 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT460275 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460461 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460540 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT460551 IFNAR1 interferon alpha and beta receptor subunit 1 2 6
MIRT460978 STK17B serine/threonine kinase 17b 2 2
MIRT461421 CTSL2 cathepsin V 1 2
MIRT461960 C3 complement C3 2 4
MIRT462529 DHODH dihydroorotate dehydrogenase (quinone) 2 6
MIRT462864 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT462917 ZNRF3 zinc and ring finger 3 2 2
MIRT463022 ZNF70 zinc finger protein 70 2 2
MIRT463074 ZNF639 zinc finger protein 639 2 2
MIRT463130 ZNF451 zinc finger protein 451 2 4
MIRT463627 YY1 YY1 transcription factor 2 2
MIRT467015 SSBP2 single stranded DNA binding protein 2 2 2
MIRT467127 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 8
MIRT468526 SERTAD2 SERTA domain containing 2 2 4
MIRT468584 SERBP1 SERPINE1 mRNA binding protein 1 2 6
MIRT469540 RBBP8 RB binding protein 8, endonuclease 2 2
MIRT469876 PURB purine rich element binding protein B 2 4
MIRT471577 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT472110 NME2 NME/NM23 nucleoside diphosphate kinase 2 2 2
MIRT472127 NME1-NME2 NME1-NME2 readthrough 2 2
MIRT472423 NCKAP1 NCK associated protein 1 2 2
MIRT472829 MTMR10 myotubularin related protein 10 2 4
MIRT473022 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT473408 MDM4 MDM4, p53 regulator 2 2
MIRT474122 LIPC lipase C, hepatic type 2 2
MIRT474927 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT476807 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT478006 DNAL1 dynein axonemal light chain 1 2 2
MIRT479200 CLCN5 chloride voltage-gated channel 5 2 6
MIRT479671 CCSER2 coiled-coil serine rich protein 2 2 2
MIRT479917 CCDC117 coiled-coil domain containing 117 2 6
MIRT479977 CARD10 caspase recruitment domain family member 10 2 2
MIRT480731 BPTF bromodomain PHD finger transcription factor 2 6
MIRT481100 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT481160 AVL9 AVL9 cell migration associated 2 6
MIRT481393 ATG12 autophagy related 12 2 2
MIRT481433 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT482083 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT484667 HOXD3 homeobox D3 2 4
MIRT485940 ECSIT ECSIT signalling integrator 2 4
MIRT485950 BRSK1 BR serine/threonine kinase 1 2 2
MIRT487600 NKD2 naked cuticle homolog 2 2 4
MIRT487666 HPCAL1 hippocalcin like 1 2 4
MIRT489966 GNB2 G protein subunit beta 2 2 2
MIRT490332 ANK1 ankyrin 1 2 4
MIRT491314 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT493193 MINK1 misshapen like kinase 1 2 4
MIRT493300 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT493816 FSCN1 fascin actin-bundling protein 1 2 2
MIRT496977 RPS6KA2 ribosomal protein S6 kinase A2 2 2
MIRT512229 ATXN3 ataxin 3 2 6
MIRT515141 ZNF799 zinc finger protein 799 2 4
MIRT516647 SMC5 structural maintenance of chromosomes 5 2 2
MIRT517952 TRIM59 tripartite motif containing 59 2 2
MIRT520971 SPPL2A signal peptide peptidase like 2A 2 4
MIRT521569 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT522918 KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 2 2
MIRT532713 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT540809 SLC35F5 solute carrier family 35 member F5 2 2
MIRT550734 PMPCA peptidase, mitochondrial processing alpha subunit 2 4
MIRT551293 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 4
MIRT559740 ACOX1 acyl-CoA oxidase 1 2 2
MIRT564410 EMILIN2 elastin microfibril interfacer 2 2 2
MIRT565240 TRAF6 TNF receptor associated factor 6 2 2
MIRT568911 ATP6V1B1 ATPase H+ transporting V1 subunit B1 2 2
MIRT575232 Fut1 fucosyltransferase 1 2 2
MIRT576224 Srsf1 serine/arginine-rich splicing factor 1 2 2
MIRT607724 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT608090 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT613920 POU3F1 POU class 3 homeobox 1 2 2
MIRT618520 SELPLG selectin P ligand 2 2
MIRT624703 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT624770 AKR1D1 aldo-keto reductase family 1 member D1 2 2
MIRT625720 SPI1 Spi-1 proto-oncogene 2 2
MIRT629975 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT631356 ZFP82 ZFP82 zinc finger protein 2 2
MIRT631426 CDNF cerebral dopamine neurotrophic factor 2 2
MIRT631665 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT631735 SF3B1 splicing factor 3b subunit 1 2 2
MIRT632334 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632419 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632531 PSMB2 proteasome subunit beta 2 2 2
MIRT633264 LDLR low density lipoprotein receptor 2 2
MIRT634327 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634753 CRCP CGRP receptor component 2 2
MIRT635412 KIAA1614 KIAA1614 2 2
MIRT636281 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636291 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT640265 FANCA Fanconi anemia complementation group A 2 2
MIRT641738 TXNL1 thioredoxin like 1 2 2
MIRT643276 ZNF566 zinc finger protein 566 2 2
MIRT643528 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643555 C11orf70 chromosome 11 open reading frame 70 2 2
MIRT647027 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647298 RBM43 RNA binding motif protein 43 2 2
MIRT648124 SEMA3E semaphorin 3E 2 4
MIRT648611 TPCN2 two pore segment channel 2 2 2
MIRT648717 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT649425 CDC14B cell division cycle 14B 2 2
MIRT650029 DSG3 desmoglein 3 2 2
MIRT650281 TAS2R5 taste 2 receptor member 5 2 2
MIRT650529 CCDC77 coiled-coil domain containing 77 2 2
MIRT654240 RNF115 ring finger protein 115 2 2
MIRT657032 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT658408 FAM212B family with sequence similarity 212 member B 2 2
MIRT659442 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT661080 FFAR2 free fatty acid receptor 2 2 2
MIRT661529 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661876 PDLIM5 PDZ and LIM domain 5 2 2
MIRT662100 ZNF419 zinc finger protein 419 2 2
MIRT662136 ZC3H8 zinc finger CCCH-type containing 8 2 2
MIRT663638 HM13 histocompatibility minor 13 2 2
MIRT663703 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663847 TRIM72 tripartite motif containing 72 2 2
MIRT664769 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665481 VSTM4 V-set and transmembrane domain containing 4 2 2
MIRT666533 RNF157 ring finger protein 157 2 2
MIRT668107 GK5 glycerol kinase 5 (putative) 2 2
MIRT668984 CKAP4 cytoskeleton associated protein 4 2 4
MIRT669742 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT671010 MOB4 MOB family member 4, phocein 2 2
MIRT671583 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT673261 INO80 INO80 complex subunit 2 2
MIRT673533 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT674714 FAM73A mitoguardin 1 2 2
MIRT675205 ZNF554 zinc finger protein 554 2 2
MIRT676488 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT676705 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676851 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT676855 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT676915 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT677000 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT677188 PDE12 phosphodiesterase 12 2 2
MIRT677473 SLC7A11 solute carrier family 7 member 11 2 2
MIRT677562 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677779 FKTN fukutin 2 2
MIRT677896 DCP1A decapping mRNA 1A 2 2
MIRT677996 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678239 HMGB1 high mobility group box 1 2 4
MIRT678313 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT678437 PDE4C phosphodiesterase 4C 2 2
MIRT678480 RNF222 ring finger protein 222 2 2
MIRT678591 ZNF91 zinc finger protein 91 2 2
MIRT678863 SLC7A14 solute carrier family 7 member 14 2 2
MIRT679241 LRP10 LDL receptor related protein 10 2 2
MIRT679388 WDR92 WD repeat domain 92 2 2
MIRT679501 ZNF106 zinc finger protein 106 2 2
MIRT679581 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679827 TMEM106B transmembrane protein 106B 2 2
MIRT679842 GPR75 G protein-coupled receptor 75 2 2
MIRT679860 ZFP30 ZFP30 zinc finger protein 2 2
MIRT680733 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT680922 STX2 syntaxin 2 2 2
MIRT680953 CEP104 centrosomal protein 104 2 2
MIRT681053 ZDBF2 zinc finger DBF-type containing 2 2 2
MIRT681967 TFCP2 transcription factor CP2 2 2
MIRT682010 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT682061 B4GALT7 beta-1,4-galactosyltransferase 7 2 4
MIRT682070 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT683356 SCARF1 scavenger receptor class F member 1 2 2
MIRT683699 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT684268 PRPF4 pre-mRNA processing factor 4 2 2
MIRT685500 MED16 mediator complex subunit 16 2 2
MIRT686876 SLC25A32 solute carrier family 25 member 32 2 2
MIRT690869 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691139 HJURP Holliday junction recognition protein 2 2
MIRT691195 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT691780 SLC24A4 solute carrier family 24 member 4 2 2
MIRT692901 MPL MPL proto-oncogene, thrombopoietin receptor 2 2
MIRT694551 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT695421 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT695956 FANCM Fanconi anemia complementation group M 2 2
MIRT696615 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT700682 PPAP2B phospholipid phosphatase 3 2 2
MIRT701215 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT702196 LRRC58 leucine rich repeat containing 58 2 2
MIRT702837 HOOK3 hook microtubule tethering protein 3 2 2
MIRT703652 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT705679 ANKRD40 ankyrin repeat domain 40 2 2
MIRT706650 SMIM19 small integral membrane protein 19 2 2
MIRT711087 NEUROD2 neuronal differentiation 2 2 2
MIRT724961 PTK6 protein tyrosine kinase 6 2 2
MIRT735597 BCL6 B-cell CLL/lymphoma 6 1 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1247 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-1247 Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780CIS)
hsa-mir-1247 Sorafenib 216239 NSC747971 approved sensitive High Hepatocellular Carcinoma tissue
hsa-mir-1247 Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-mir-1247 Androstenedione 6128 NSC9563 resistant cell line (MCF-7)
hsa-mir-1247 Androstenedione+Anastrozole resistant cell line (MCF-7)
hsa-mir-1247 Androstenedione+Letrozole resistant cell line (MCF-7)
hsa-mir-1247 Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-mir-1247 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-mir-1247 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1247-3p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (SW1990)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-1247-3p Yuanhuadine 6440572 resistant High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-1247-3p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-1247-3p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-1247-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-1247-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-1247-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-1247-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-1247-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-1247-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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