pre-miRNA Information
pre-miRNA hsa-mir-4747   
Genomic Coordinates chr19: 4932687 - 4932740
Description Homo sapiens miR-4747 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4747-5p
Sequence 1| AGGGAAGGAGGCUUGGUCUUAG |22
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs560927363 4 dbSNP
rs1471226927 10 dbSNP
rs763137545 12 dbSNP
rs767337154 15 dbSNP
rs775298039 16 dbSNP
rs760472311 19 dbSNP
rs1207950315 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TTLL9   
Synonyms C20orf125
Description tubulin tyrosine ligase like 9
Transcript NM_001008409   
Expression
Putative miRNA Targets on TTLL9
3'UTR of TTLL9
(miRNA target sites are highlighted)
>TTLL9|NM_001008409|3'UTR
   1 TCCCCAGCTGCCAGGAGGAAATCAGCCTTAGCAG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' gaUUCUGGUUCGGAGGAAggga 5'
            |:||  || |  ||||    
Target 5' ggAGGA--AATCAGCCTTagca 3'
14 - 33 92.00 -8.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM9409298 19 COSMIC
COSM6811629 29 COSMIC
COSN511332 36 COSMIC
COSN18723740 57 COSMIC
COSN18742976 57 COSMIC
COSN1247479 65 COSMIC
COSN9125618 87 COSMIC
COSN8868581 116 COSMIC
COSN15016798 370 COSMIC
COSN26605148 718 COSMIC
COSN7089066 1136 COSMIC
COSN7089067 1355 COSMIC
COSN9125620 1946 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs373854935 1 dbSNP
rs1267028725 7 dbSNP
rs1357263071 19 dbSNP
rs769491446 21 dbSNP
rs775414005 26 dbSNP
rs763023511 27 dbSNP
rs1183518305 31 dbSNP
rs1260501394 41 dbSNP
rs1257493653 45 dbSNP
rs764099104 47 dbSNP
rs761440396 49 dbSNP
rs759022927 50 dbSNP
rs764688059 50 dbSNP
rs766982209 51 dbSNP
rs539731138 52 dbSNP
rs1166967262 54 dbSNP
rs765352958 55 dbSNP
rs551478067 56 dbSNP
rs553667704 57 dbSNP
rs752349075 57 dbSNP
rs781276229 58 dbSNP
rs1354782693 59 dbSNP
rs1394244253 61 dbSNP
rs746135823 71 dbSNP
rs1340852564 72 dbSNP
rs770025223 73 dbSNP
rs1272824776 75 dbSNP
rs1171149903 76 dbSNP
rs775473185 84 dbSNP
rs1004463376 87 dbSNP
rs1202630610 92 dbSNP
rs1343912034 93 dbSNP
rs1298035544 95 dbSNP
rs181933010 96 dbSNP
rs573809820 105 dbSNP
rs1448782747 110 dbSNP
rs1000963088 111 dbSNP
rs6058498 116 dbSNP
rs956644859 117 dbSNP
rs1431835981 119 dbSNP
rs556719578 125 dbSNP
rs1467513656 128 dbSNP
rs988066674 139 dbSNP
rs1416517367 142 dbSNP
rs1182977829 148 dbSNP
rs1389372829 159 dbSNP
rs923147303 160 dbSNP
rs1023002797 161 dbSNP
rs970062247 162 dbSNP
rs758403143 164 dbSNP
rs778429167 165 dbSNP
rs1251532239 166 dbSNP
rs1361721995 172 dbSNP
rs1319724660 180 dbSNP
rs978838025 181 dbSNP
rs1291884632 185 dbSNP
rs578152624 188 dbSNP
rs1228786763 191 dbSNP
rs1349848142 193 dbSNP
rs985967235 196 dbSNP
rs1351271224 197 dbSNP
rs1293174807 200 dbSNP
rs1456668606 206 dbSNP
rs752051268 207 dbSNP
rs1158637292 208 dbSNP
rs1413608913 220 dbSNP
rs1457158463 224 dbSNP
rs1410478322 236 dbSNP
rs141164955 239 dbSNP
rs1325174586 252 dbSNP
rs775593292 259 dbSNP
rs1250727418 261 dbSNP
rs1394883672 263 dbSNP
rs1038808646 268 dbSNP
rs1487323807 278 dbSNP
rs1388309438 290 dbSNP
rs1248217971 291 dbSNP
rs1327019477 294 dbSNP
rs919946097 300 dbSNP
rs545690357 312 dbSNP
rs781653191 326 dbSNP
rs912138301 327 dbSNP
rs944988028 335 dbSNP
rs896713349 339 dbSNP
rs1385280764 345 dbSNP
rs1332814997 356 dbSNP
rs563921905 358 dbSNP
rs976369387 369 dbSNP
rs920906729 370 dbSNP
rs1274380577 372 dbSNP
rs904981331 374 dbSNP
rs1000613623 393 dbSNP
rs1363839465 403 dbSNP
rs1174804354 404 dbSNP
rs1431080942 411 dbSNP
rs1426912384 421 dbSNP
rs1358843061 424 dbSNP
rs932332441 425 dbSNP
rs1464285493 427 dbSNP
rs1048110425 434 dbSNP
rs1246065761 451 dbSNP
rs1032474589 460 dbSNP
rs1194444597 470 dbSNP
rs892140051 475 dbSNP
rs888197418 479 dbSNP
rs572911536 480 dbSNP
rs1304455154 507 dbSNP
rs564361130 511 dbSNP
rs939868984 513 dbSNP
rs56398306 516 dbSNP
rs763083099 518 dbSNP
rs1323010015 519 dbSNP
rs1436432948 527 dbSNP
rs1037308392 529 dbSNP
rs1402191774 540 dbSNP
rs895724783 541 dbSNP
rs150714695 546 dbSNP
rs954590393 548 dbSNP
rs1022899480 549 dbSNP
rs905827332 550 dbSNP
rs746201207 552 dbSNP
rs1388056900 556 dbSNP
rs1017428024 563 dbSNP
rs1033093946 565 dbSNP
rs561739849 569 dbSNP
rs974186163 570 dbSNP
rs529002053 571 dbSNP
rs1459438251 574 dbSNP
rs988980871 579 dbSNP
rs1165924009 580 dbSNP
rs1281251452 586 dbSNP
rs1395563584 588 dbSNP
rs1340364683 592 dbSNP
rs1300252435 597 dbSNP
rs929991918 598 dbSNP
rs139000015 600 dbSNP
rs562745335 614 dbSNP
rs1393743770 615 dbSNP
rs749753143 616 dbSNP
rs1313000959 622 dbSNP
rs1294375901 627 dbSNP
rs1428684476 630 dbSNP
rs1045675421 632 dbSNP
rs1462312019 633 dbSNP
rs1342780373 634 dbSNP
rs533076633 635 dbSNP
rs577973822 636 dbSNP
rs974941926 639 dbSNP
rs1181623150 652 dbSNP
rs187570895 653 dbSNP
rs1251086186 655 dbSNP
rs1340549472 658 dbSNP
rs768415681 661 dbSNP
rs1276351131 664 dbSNP
rs922189869 667 dbSNP
rs1196689229 672 dbSNP
rs1484364931 673 dbSNP
rs936797043 675 dbSNP
rs932284836 676 dbSNP
rs1264165242 679 dbSNP
rs778428446 680 dbSNP
rs370873900 689 dbSNP
rs747701481 693 dbSNP
rs1256314757 694 dbSNP
rs1206009252 701 dbSNP
rs1279747139 702 dbSNP
rs1482533974 703 dbSNP
rs545678854 704 dbSNP
rs768531223 711 dbSNP
rs1428357181 712 dbSNP
rs1330495850 716 dbSNP
rs892193815 718 dbSNP
rs1387987351 727 dbSNP
rs1431069473 729 dbSNP
rs1036851454 731 dbSNP
rs868393651 733 dbSNP
rs1374338756 735 dbSNP
rs1459367257 746 dbSNP
rs1464426337 749 dbSNP
rs895631347 756 dbSNP
rs1009258891 761 dbSNP
rs1304587685 765 dbSNP
rs1029997450 766 dbSNP
rs1381489643 768 dbSNP
rs1254188245 776 dbSNP
rs190649769 781 dbSNP
rs774430370 782 dbSNP
rs1354456574 789 dbSNP
rs949869367 791 dbSNP
rs1229437253 792 dbSNP
rs1302689226 794 dbSNP
rs1280498072 795 dbSNP
rs142685502 797 dbSNP
rs1212854639 799 dbSNP
rs772772052 800 dbSNP
rs1485731753 807 dbSNP
rs1227186907 809 dbSNP
rs573163089 814 dbSNP
rs182153872 815 dbSNP
rs1239284845 816 dbSNP
rs1017899460 817 dbSNP
rs963260045 828 dbSNP
rs973615548 848 dbSNP
rs1395051937 849 dbSNP
rs1027055402 850 dbSNP
rs1455673534 853 dbSNP
rs1301780435 857 dbSNP
rs1410212241 861 dbSNP
rs773155838 863 dbSNP
rs1345273615 876 dbSNP
rs1477815650 884 dbSNP
rs951449420 887 dbSNP
rs1201380840 901 dbSNP
rs1209768442 901 dbSNP
rs556469821 902 dbSNP
rs1247901010 905 dbSNP
rs1000199095 908 dbSNP
rs760566040 911 dbSNP
rs770825691 914 dbSNP
rs1010708937 917 dbSNP
rs1019004782 918 dbSNP
rs949380040 923 dbSNP
rs1223919932 924 dbSNP
rs1343763489 927 dbSNP
rs1272730956 930 dbSNP
rs966143022 931 dbSNP
rs974889381 934 dbSNP
rs578157339 936 dbSNP
rs981050543 937 dbSNP
rs1346954351 947 dbSNP
rs926846383 948 dbSNP
rs1029190659 952 dbSNP
rs1400270351 953 dbSNP
rs1175786324 955 dbSNP
rs936869829 957 dbSNP
rs1389915939 958 dbSNP
rs952436289 965 dbSNP
rs1187127912 981 dbSNP
rs1190271789 983 dbSNP
rs1489722764 985 dbSNP
rs540566222 987 dbSNP
rs538941101 990 dbSNP
rs961082566 1002 dbSNP
rs1276018268 1003 dbSNP
rs972439815 1006 dbSNP
rs1379406366 1012 dbSNP
rs945096943 1014 dbSNP
rs759236680 1015 dbSNP
rs1051476366 1017 dbSNP
rs1390010090 1017 dbSNP
rs554413249 1018 dbSNP
rs1270713555 1020 dbSNP
rs890127429 1024 dbSNP
rs949858064 1036 dbSNP
rs1314892367 1042 dbSNP
rs1007613130 1045 dbSNP
rs1038963621 1054 dbSNP
rs1167026322 1055 dbSNP
rs899064183 1063 dbSNP
rs1181820102 1066 dbSNP
rs1420784248 1066 dbSNP
rs994703692 1068 dbSNP
rs1044293558 1069 dbSNP
rs927178038 1074 dbSNP
rs1485792667 1079 dbSNP
rs1313384862 1081 dbSNP
rs774822348 1082 dbSNP
rs186753664 1088 dbSNP
rs1273587331 1093 dbSNP
rs540190693 1099 dbSNP
rs1465283946 1102 dbSNP
rs1354229437 1108 dbSNP
rs1295195351 1118 dbSNP
rs1415476669 1122 dbSNP
rs1350039862 1123 dbSNP
rs765561776 1128 dbSNP
rs561677063 1130 dbSNP
rs1040402026 1132 dbSNP
rs34764382 1141 dbSNP
rs970773012 1141 dbSNP
rs981153490 1155 dbSNP
rs867311963 1180 dbSNP
rs1355446962 1182 dbSNP
rs1210571317 1186 dbSNP
rs1404083032 1188 dbSNP
rs1420741160 1194 dbSNP
rs926926209 1197 dbSNP
rs901969196 1199 dbSNP
rs1250876156 1214 dbSNP
rs762700620 1215 dbSNP
rs1029139596 1216 dbSNP
rs768366400 1218 dbSNP
rs6061045 1220 dbSNP
rs914079361 1221 dbSNP
rs763102638 1234 dbSNP
rs1233920302 1243 dbSNP
rs1328619301 1256 dbSNP
rs1015181452 1262 dbSNP
rs190095953 1275 dbSNP
rs1051527493 1277 dbSNP
rs911600710 1283 dbSNP
rs1293304190 1286 dbSNP
rs1434770221 1287 dbSNP
rs764217371 1289 dbSNP
rs145090295 1292 dbSNP
rs1397255977 1298 dbSNP
rs972429728 1299 dbSNP
rs528916470 1305 dbSNP
rs1461475012 1313 dbSNP
rs11697022 1322 dbSNP
rs1410549229 1324 dbSNP
rs943078374 1337 dbSNP
rs762266024 1338 dbSNP
rs1408267142 1342 dbSNP
rs1039090867 1344 dbSNP
rs1452363769 1363 dbSNP
rs899121884 1367 dbSNP
rs994705697 1372 dbSNP
rs1464426521 1373 dbSNP
rs1047605554 1375 dbSNP
rs1218122208 1377 dbSNP
rs1412853273 1378 dbSNP
rs866760743 1380 dbSNP
rs1459255097 1390 dbSNP
rs1217787117 1398 dbSNP
rs886276902 1401 dbSNP
rs1304684952 1405 dbSNP
rs917002046 1406 dbSNP
rs1163435214 1408 dbSNP
rs1387173934 1417 dbSNP
rs1286539140 1421 dbSNP
rs182558347 1433 dbSNP
rs188187497 1436 dbSNP
rs979920247 1439 dbSNP
rs1396637809 1440 dbSNP
rs533189360 1440 dbSNP
rs1293689869 1441 dbSNP
rs935868045 1443 dbSNP
rs1259581743 1447 dbSNP
rs1054741350 1455 dbSNP
rs1255590955 1459 dbSNP
rs913154845 1460 dbSNP
rs1208965226 1465 dbSNP
rs551300380 1468 dbSNP
rs193175077 1471 dbSNP
rs989732308 1472 dbSNP
rs185418189 1475 dbSNP
rs966880799 1477 dbSNP
rs996243241 1477 dbSNP
rs1301804002 1479 dbSNP
rs1361997456 1479 dbSNP
rs987623978 1483 dbSNP
rs911668180 1486 dbSNP
rs188983745 1490 dbSNP
rs1173960859 1493 dbSNP
rs1428887640 1497 dbSNP
rs1371221935 1498 dbSNP
rs1271221160 1500 dbSNP
rs1333796061 1504 dbSNP
rs750923667 1505 dbSNP
rs1248300486 1506 dbSNP
rs1255535970 1508 dbSNP
rs376361287 1509 dbSNP
rs1185977685 1510 dbSNP
rs1486735953 1520 dbSNP
rs920264261 1524 dbSNP
rs887917125 1527 dbSNP
rs1006399818 1538 dbSNP
rs930273531 1541 dbSNP
rs1337887793 1545 dbSNP
rs1015585958 1547 dbSNP
rs1047657748 1551 dbSNP
rs750870356 1552 dbSNP
rs1228765339 1556 dbSNP
rs962363782 1564 dbSNP
rs1479767289 1573 dbSNP
rs1176877233 1574 dbSNP
rs1292127188 1577 dbSNP
rs567361701 1580 dbSNP
rs1252575121 1589 dbSNP
rs1408952548 1595 dbSNP
rs531688870 1604 dbSNP
rs1169483042 1611 dbSNP
rs550276737 1618 dbSNP
rs1367819956 1619 dbSNP
rs192600038 1621 dbSNP
rs1476239293 1623 dbSNP
rs114350216 1625 dbSNP
rs1181690988 1626 dbSNP
rs906650012 1630 dbSNP
rs554077096 1637 dbSNP
rs1002704865 1640 dbSNP
rs1024006947 1649 dbSNP
rs566337942 1661 dbSNP
rs114986928 1664 dbSNP
rs1460125227 1665 dbSNP
rs1230900036 1669 dbSNP
rs1336357081 1673 dbSNP
rs1293405422 1677 dbSNP
rs1237816243 1684 dbSNP
rs555400395 1685 dbSNP
rs1010881669 1692 dbSNP
rs1021245572 1698 dbSNP
rs1350517341 1704 dbSNP
rs1462978929 1710 dbSNP
rs573711198 1710 dbSNP
rs1158539362 1711 dbSNP
rs1395249737 1711 dbSNP
rs1468737788 1712 dbSNP
rs1167985892 1720 dbSNP
rs1182964282 1725 dbSNP
rs1034105567 1727 dbSNP
rs34089906 1730 dbSNP
rs1251643071 1737 dbSNP
rs543959797 1742 dbSNP
rs556187571 1744 dbSNP
rs1469320824 1748 dbSNP
rs1228868437 1752 dbSNP
rs1273200429 1768 dbSNP
rs1348088178 1769 dbSNP
rs761042903 1769 dbSNP
rs756370085 1770 dbSNP
rs1239468488 1771 dbSNP
rs1305578449 1775 dbSNP
rs1301011385 1776 dbSNP
rs974901521 1779 dbSNP
rs1204030574 1784 dbSNP
rs913136466 1787 dbSNP
rs992774802 1790 dbSNP
rs1395132926 1799 dbSNP
rs778645409 1807 dbSNP
rs945989141 1808 dbSNP
rs976040745 1815 dbSNP
rs923244186 1816 dbSNP
rs932000128 1819 dbSNP
rs747706478 1820 dbSNP
rs983067930 1821 dbSNP
rs766508039 1826 dbSNP
rs1195907802 1836 dbSNP
rs1455032052 1862 dbSNP
rs577683457 1865 dbSNP
rs370747219 1866 dbSNP
rs907823301 1869 dbSNP
rs1285787923 1874 dbSNP
rs949970187 1879 dbSNP
rs6061046 1886 dbSNP
rs777306936 1888 dbSNP
rs139924671 1889 dbSNP
rs746502425 1890 dbSNP
rs1236304808 1905 dbSNP
rs779091944 1918 dbSNP
rs1167509868 1921 dbSNP
rs893882026 1921 dbSNP
rs1319087772 1925 dbSNP
rs6121290 1930 dbSNP
rs770911462 1942 dbSNP
rs1010934115 1943 dbSNP
rs527570770 1949 dbSNP
rs1431310391 1957 dbSNP
rs1310519174 1970 dbSNP
rs542559175 1972 dbSNP
rs1358111492 1975 dbSNP
rs1020964287 1976 dbSNP
rs1166627254 1977 dbSNP
rs560925639 1979 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' gauucugguucgGAGGAAGGGa 5'
                      ||||||||| 
Target 5' ------------CUCCUUCCCu 3'
1 - 10
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000375921.2 | 3UTR | CUCCUUCCCUCCCACCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
215 hsa-miR-4747-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061689 BTG2 BTG anti-proliferation factor 2 2 2
MIRT062834 BCL7A BCL tumor suppressor 7A 2 2
MIRT079371 CCDC137 coiled-coil domain containing 137 2 2
MIRT081190 MIDN midnolin 2 4
MIRT081724 ZNF507 zinc finger protein 507 2 2
MIRT110565 ZMYND11 zinc finger MYND-type containing 11 2 2
MIRT133724 SKI SKI proto-oncogene 2 4
MIRT146689 MINK1 misshapen like kinase 1 2 2
MIRT150676 SLC27A1 solute carrier family 27 member 1 2 2
MIRT159196 NRBP1 nuclear receptor binding protein 1 2 2
MIRT180865 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT190659 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT196111 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT232390 SP1 Sp1 transcription factor 2 2
MIRT331070 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT338632 SHMT2 serine hydroxymethyltransferase 2 2 2
MIRT407441 CTDSP1 CTD small phosphatase 1 2 2
MIRT444276 NKX6-1 NK6 homeobox 1 2 2
MIRT444834 PDE6D phosphodiesterase 6D 2 2
MIRT445452 EXT1 exostosin glycosyltransferase 1 2 2
MIRT445644 NPY4R neuropeptide Y receptor Y4 2 2
MIRT446157 RPL12 ribosomal protein L12 2 2
MIRT446608 HIP1 huntingtin interacting protein 1 2 2
MIRT447108 CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2 2
MIRT449314 MRO maestro 2 2
MIRT450305 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT451245 ZNF444 zinc finger protein 444 2 2
MIRT451714 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT451908 ILK integrin linked kinase 2 2
MIRT452183 KIAA1456 KIAA1456 2 2
MIRT452610 REPIN1 replication initiator 1 2 2
MIRT453422 GLG1 golgi glycoprotein 1 2 2
MIRT454006 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT455072 ARHGAP39 Rho GTPase activating protein 39 2 2
MIRT455319 TTLL9 tubulin tyrosine ligase like 9 2 2
MIRT455357 KDM5C lysine demethylase 5C 2 2
MIRT455589 TAF12 TATA-box binding protein associated factor 12 2 2
MIRT455711 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT455860 TMEM254 transmembrane protein 254 2 2
MIRT455919 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT455946 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT456935 LRP10 LDL receptor related protein 10 2 2
MIRT457223 AP3D1 adaptor related protein complex 3 delta 1 subunit 2 2
MIRT457431 NOL10 nucleolar protein 10 2 2
MIRT457470 SLC35F6 solute carrier family 35 member F6 2 2
MIRT457907 ZNF212 zinc finger protein 212 2 2
MIRT458046 TSEN54 tRNA splicing endonuclease subunit 54 2 2
MIRT458073 RNLS renalase, FAD dependent amine oxidase 2 2
MIRT458234 NXPH3 neurexophilin 3 2 2
MIRT458307 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458378 ITM2C integral membrane protein 2C 2 2
MIRT458967 ZNF436 zinc finger protein 436 2 2
MIRT459099 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT459446 TMEM37 transmembrane protein 37 2 2
MIRT459671 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT460727 ASXL3 additional sex combs like 3, transcriptional regulator 2 2
MIRT460744 SRP14 signal recognition particle 14 2 2
MIRT461531 C14orf1 ergosterol biosynthesis 28 homolog 2 2
MIRT461752 DDX11 DEAD/H-box helicase 11 2 2
MIRT461837 F2RL3 F2R like thrombin or trypsin receptor 3 2 2
MIRT462019 RIF1 replication timing regulatory factor 1 2 2
MIRT462631 PHF5A PHD finger protein 5A 2 2
MIRT462772 ZNF8 zinc finger protein 8 2 2
MIRT463032 ZNF689 zinc finger protein 689 2 2
MIRT463886 WNT7B Wnt family member 7B 2 2
MIRT463995 WDTC1 WD and tetratricopeptide repeats 1 2 2
MIRT464371 URM1 ubiquitin related modifier 1 2 2
MIRT465342 TPM3 tropomyosin 3 2 4
MIRT465515 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465602 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT465697 TNPO2 transportin 2 2 10
MIRT466988 SSRP1 structure specific recognition protein 1 2 4
MIRT467630 SLC7A5 solute carrier family 7 member 5 2 2
MIRT468132 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT468322 SF3B3 splicing factor 3b subunit 3 2 2
MIRT468502 SESN2 sestrin 2 2 2
MIRT468881 RREB1 ras responsive element binding protein 1 2 2
MIRT469322 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT469562 RARA retinoic acid receptor alpha 2 2
MIRT469898 PTRF caveolae associated protein 1 2 2
MIRT470045 PTGFRN prostaglandin F2 receptor inhibitor 2 2
MIRT470068 PTGES2 prostaglandin E synthase 2 2 2
MIRT470238 PRRC2A proline rich coiled-coil 2A 2 2
MIRT470390 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT470500 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT470689 POLR2D RNA polymerase II subunit D 2 2
MIRT470704 POGK pogo transposable element derived with KRAB domain 2 2
MIRT471083 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT472482 NACC2 NACC family member 2 2 2
MIRT473583 MAT2A methionine adenosyltransferase 2A 2 2
MIRT474554 KLHDC3 kelch domain containing 3 2 2
MIRT474651 KLF13 Kruppel like factor 13 2 2
MIRT474843 KHSRP KH-type splicing regulatory protein 2 2
MIRT474934 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475573 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 2
MIRT476045 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT476080 GRB2 growth factor receptor bound protein 2 2 2
MIRT476440 GBA2 glucosylceramidase beta 2 2 2
MIRT476764 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT478785 CRTC2 CREB regulated transcription coactivator 2 2 2
MIRT479287 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT479505 CDH6 cadherin 6 2 2
MIRT479732 CCND1 cyclin D1 2 6
MIRT480352 C5orf24 chromosome 5 open reading frame 24 2 2
MIRT480407 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480859 BHLHB9 basic helix-loop-helix family member b9 2 2
MIRT481445 ARRB2 arrestin beta 2 2 2
MIRT481732 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT481824 AP2M1 adaptor related protein complex 2 mu 1 subunit 2 2
MIRT482566 ABHD2 abhydrolase domain containing 2 2 2
MIRT482607 ABHD14B abhydrolase domain containing 14B 2 2
MIRT483144 SYCE1L synaptonemal complex central element protein 1 like 2 2
MIRT483214 APOA1 apolipoprotein A1 2 6
MIRT483878 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT483917 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT483939 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484420 SNX19 sorting nexin 19 2 2
MIRT484489 SLC9A1 solute carrier family 9 member A1 2 2
MIRT484612 SIX3 SIX homeobox 3 2 6
MIRT484705 RNF11 ring finger protein 11 2 2
MIRT485107 SHISA6 shisa family member 6 2 2
MIRT485354 MYO1C myosin IC 2 4
MIRT485609 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT487311 GLTSCR1 BRD4 interacting chromatin remodeling complex associated protein 2 2
MIRT487417 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT487695 CDK14 cyclin dependent kinase 14 2 2
MIRT487791 GPR20 G protein-coupled receptor 20 2 4
MIRT488042 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT488058 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT488237 DNLZ DNL-type zinc finger 2 4
MIRT488764 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT489401 TUBB2A tubulin beta 2A class IIa 2 2
MIRT489777 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490099 FN3K fructosamine 3 kinase 2 2
MIRT490290 ISL2 ISL LIM homeobox 2 2 2
MIRT490378 LHFPL3 LHFPL tetraspan subfamily member 3 2 2
MIRT491329 GFER growth factor, augmenter of liver regeneration 2 2
MIRT491435 MSX2 msh homeobox 2 2 2
MIRT491769 ZNF385A zinc finger protein 385A 2 2
MIRT491922 WNK2 WNK lysine deficient protein kinase 2 2 2
MIRT491983 UNK unkempt family zinc finger 2 2
MIRT492228 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492404 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT492767 PDGFB platelet derived growth factor subunit B 2 2
MIRT492966 NCS1 neuronal calcium sensor 1 2 2
MIRT493295 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT493650 HDLBP high density lipoprotein binding protein 2 2
MIRT493913 FAM127B retrotransposon Gag like 8A 2 4
MIRT495601 NKX2-5 NK2 homeobox 5 2 2
MIRT496875 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT498514 MYH14 myosin heavy chain 14 2 2
MIRT499178 RBPJL recombination signal binding protein for immunoglobulin kappa J region like 2 2
MIRT502143 KIF5B kinesin family member 5B 2 8
MIRT502692 CSNK1G1 casein kinase 1 gamma 1 2 4
MIRT508460 HOXB6 homeobox B6 2 4
MIRT510430 ZNF207 zinc finger protein 207 2 6
MIRT511837 GPATCH8 G-patch domain containing 8 2 4
MIRT512368 CPM carboxypeptidase M 2 2
MIRT512506 BTBD19 BTB domain containing 19 2 2
MIRT513065 ANKRD45 ankyrin repeat domain 45 2 2
MIRT513267 SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 2 4
MIRT513575 EVX1 even-skipped homeobox 1 2 2
MIRT515051 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT515790 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT521657 PRKD3 protein kinase D3 2 2
MIRT522679 LUZP1 leucine zipper protein 1 2 6
MIRT528845 RAB32 RAB32, member RAS oncogene family 2 2
MIRT533569 TOR1AIP1 torsin 1A interacting protein 1 2 2
MIRT543738 DHCR7 7-dehydrocholesterol reductase 2 2
MIRT544295 TSPYL1 TSPY like 1 2 2
MIRT544857 MYH2 myosin heavy chain 2 2 4
MIRT557323 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT560522 TMEM98 transmembrane protein 98 2 2
MIRT561565 SLC6A9 solute carrier family 6 member 9 2 2
MIRT562374 ERI2 ERI1 exoribonuclease family member 2 2 2
MIRT565780 SEMA6D semaphorin 6D 2 2
MIRT569548 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT569944 PRRT2 proline rich transmembrane protein 2 2 2
MIRT570016 COL1A2 collagen type I alpha 2 chain 2 2
MIRT572163 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT572322 HSPB6 heat shock protein family B (small) member 6 2 2
MIRT573495 IQSEC3 IQ motif and Sec7 domain 3 2 2
MIRT574139 MARVELD1 MARVEL domain containing 1 2 2
MIRT609449 CCDC149 coiled-coil domain containing 149 2 2
MIRT610619 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT623355 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT629854 ACOX1 acyl-CoA oxidase 1 2 2
MIRT630516 CDC73 cell division cycle 73 2 2
MIRT632535 PSMB2 proteasome subunit beta 2 2 2
MIRT633975 SLC35E2 solute carrier family 35 member E2 2 2
MIRT636408 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT641722 LTBR lymphotoxin beta receptor 2 2
MIRT642661 RGS6 regulator of G protein signaling 6 2 2
MIRT649649 MAST3 microtubule associated serine/threonine kinase 3 2 2
MIRT650367 MOCS3 molybdenum cofactor synthesis 3 2 2
MIRT651355 ZBTB40 zinc finger and BTB domain containing 40 2 2
MIRT664840 HUS1 HUS1 checkpoint clamp component 2 2
MIRT667322 MYH9 myosin heavy chain 9 2 2
MIRT670680 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT674922 TRPM6 transient receptor potential cation channel subfamily M member 6 2 2
MIRT675919 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT676493 GJD3 gap junction protein delta 3 2 2
MIRT680162 ZDHHC20 zinc finger DHHC-type containing 20 2 2
MIRT688008 GSN gelsolin 2 2
MIRT688997 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT700337 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT701344 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT703519 FKBP15 FK506 binding protein 15 2 2
MIRT703901 EPT1 selenoprotein I 2 2
MIRT705565 ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 2 2
MIRT709709 DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 2 2
MIRT713108 TMBIM4 transmembrane BAX inhibitor motif containing 4 2 2
MIRT718426 ZNF85 zinc finger protein 85 2 2
MIRT719236 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719326 STAC SH3 and cysteine rich domain 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4747 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-4747-5p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-4747-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4747-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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