miRTarBase - #MIRT455922


—
pre-miRNA Information
pre-miRNA hsa-mir-4270   
Genomic Coordinates chr3: 15496239 - 15496308
Description Homo sapiens miR-4270 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4270
Sequence 11| UCAGGGAGUCAGGGGAGGGC |30
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs991570490 2 dbSNP
rs1417709982 10 dbSNP
rs960511282 12 dbSNP
rs928808979 14 dbSNP
rs1372156971 15 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RAPGEF1   
Synonyms C3G, GRF2
Description Rap guanine nucleotide exchange factor 1
Transcript NM_005312   
Other Transcripts NM_198679   
Expression
Putative miRNA Targets on RAPGEF1
3'UTR of RAPGEF1
(miRNA target sites are highlighted)		 
>RAPGEF1|NM_005312|3'UTR
   1 GAGCAGACGCCGGGATCCAGGAGAATGCTCGAGGGGCGCAGAGGGCAGCTCCCAGACCGGAGAGGACCTTGGACCTGTTA
  81 GGCGCATGGCAGGAGTCCCGGCCTCGGAGCCATGAGGCTGGCCAGCCCTCAGCGGGGCCGGGCGGGAGCTGGAGCCTGCC
 161 AGCCGCTTCCTGCCTCCTTCCTCTGTGGGAGCAGACCCGTGGGCCTCAGGGCAGCCAGCAGGCAGGTCTTGTTGCCAATT
 241 TACAAACCGGTGGTTTTCTGGTTTGGTTTTGTTTTCTGCTTTTACTTCCATCTCTCCCCTCTTGACCTTCCACCCACTCC
 321 CCTCCAGGGAGAGAGCAGCAGAGACCTCATCAGCAGACCAAGGAAGTGGTGGGTGCTCCCCCTCCCTAAGCTCCAGGGTC
 401 CCTGAATCTTCTGAAATCTCAAATGAGTGGAGGCCTCCTGGGGTGGCCTGTCCTGCAGGGGCCCTGGAATGGGGGCAAGC
 481 AGCTGGGTGGGCAGAATGCAGAGTAGACTCGGGGGAGGATCCTTTCACTTTCCGCTTCCCCTTCTGATGCATGGAGGATG
 561 GTGTGAGCTTTTCAGCAGGCCCGGAAAGGTACGCAGGTGACGCCTTAGCAGCCCCGCAGCTGGTGCTCTGCCCCGCGGTA
 641 CTGGCGCCATCAGGGCCTCCCTTGCCCGCCTGAGAGCAGCAGCAGTCTCTGTCATCCCGTCGCCCCTTACCCCCCACCCC
 721 AGGCCACTGGGCCCCTCCCACACCACCTGGGGAGCTGAGAAGAGGAGGCTGGAGTAAGGGAGGACTTGATCATCCAAGAA
 801 ATACTTTTTATTGCTGGGAGTCTTCTGAACCTCACCAAACTGAGGCCAGAGCTGAGCTCCTGGGGGAGTTAATTCAGAGG
 881 GGAGAGGCCAGCACCTCCCTCCTCCATCGCTCGCTGTGTGCCTTAAACTCCATCTCATGTCCCTCCCCATCCCCTGGCTT
 961 TCCCTCCCTCCTTGCCCCATCCTGGGCCAGCCAGCAGGGCTCCTCCTCTGGCTCTTCAGACCTTTCAGCCAGTGCTGTCA
1041 GTGCCCCTGGGAGGGAAGGGCATCCCTGAGGCACCCGAATGGTCCCTCAGGGTGCAGGGAGGCAGAAGCCTGGCCACAGA
1121 GGAGCCTCCTAAGGCAGCAGCTGCAGCAAGCGCACCCTCTCCCCACTCTCCCCACGCCAGAGCGGCTTCCAGAGCAGATG
1201 CTGTTTCCATCCTCCTCGTCAAAACCATTCTCGCTGCTGAGCTTGACAATCTGGGCAAGGCTTGTGGGGCGCTTGACAAA
1281 CAGAATCTGCCCTGTGCCGCCTGGTTCCGTGGCCTCCAGCATGAGCCTGCAGGCAGGGCGCTGCGGGAACCCAGTTGTGC
1361 TGCCCCAGCCCATGCCTCCGGGTCTGCTGTGCATGAATGAGTGCTCACTTGTCCCGGGTTTAGGACGTGGTCAAGTGAAC
1441 AGCAGGGTCTAACTGTGCTTACTTAGCCCAGTTCAAACAGAACAAAGGAAAAATATAGAAAGCAACATCTGTTGATCATT
1521 TAGGTTTTTTTTTAAACCACCATGTCACTTTGAGTCCTTCATGGGTTTTTGAACAGCATTTATCAAGAAGAAAATGTGGG
1601 CTTTTTCCCCTCTCCCGTGTTTTGTTTGTCCTGTAGATAGAGGGAGGAAAGCCGTGCAGTGGCAGGCGGGACCCCCTCTG
1681 GTGGCGGGACCCCCTCTTGCGGTGGTCTTGCGGGGCCAGCCGGGACCTGTCACTTTATTATTTAAGGAGTGTGTGTGTAG
1761 AGTCGCTGGCTTATTAACAGTATTGTGTGTGGGTTGGGTTTTTAGTTTGTTCCTTCTTTTTGAAGTCCCTTCATTTCAAT
1841 CCTTGACTCTCTCTCCCCTTCCCTTGCCCAGCTCTGTTGAATGCTGCTGTGCGCGTGTGAGGGCCGCTCTGCACACAGGG
1921 CCCTTGGGTTGTGTGAACTGAAATTCTCCCTGTATTTGTGAGACTCGCAGGAGTCCCCATCTGTAGCACAGGCAATGCCA
2001 GTGCCATGCTGCAGCCTCAGAAACCAGGCCTCTCACTCCAGCAGCAGGCAGAACCGTGTCTGTGGTCGGGTGCTGTCCAC
2081 AGCTCTGTCTGCCTTGTTCTTGGGCTTGAGCTGGATAGAGGTGGGGTCTCTTCACCTTCCCTGAATTCAGAACAGACCCT
2161 GTGCCTGGCCCCAGTGTGCCCAGGCAATTCCCCAGGCCCTCACTGGGAGCCCTTGGTGTTCTGAGCAGCAGGGCCCAGGC
2241 AGCACATGAGCAGTGCCCAGGGGCTCCCTGCGTGAGGACGGCAAGGTGCGATGTATGTCTAACTTATTGATGGCAGGCAG
2321 CCCCCTGTGCCCCCTAAGCCTGGCCCTGGTTATTGCTGAGCTCTGTGCTCAGTGCTGCGGCCTGGCCGTGGCTCGTCTGT
2401 TCCTTTGGGGGGCCCGGGCGGGTTGTGGGAATCAGTCTTCACAGACAGACGTGAGCCAGGCGGAGGACTCGTTCCTTGCA
2481 GAGGTCAGTCCTCACCTGCAGGTGTCGGGGTGGGGGGGGGCAAGGAGGGGCAGGCACACACCATGTCTGACCTGAACCCG
2561 ATTCTGGGGAGCATCTTCCCGCTCCGGCCCCACGACCTCCACAGGGTTACATTGTAATATATATGCCCCAGCTAACCTGT
2641 CTGATGGTGGCATCTTCCTGCAGACATTTCAAACATGTAACTTTTATATGAAAAAAAATAAACACAGATGAAAGCTGCCC
2721 AATGCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgGGAGGGGACUGAGGGACu 5'
            |:|:||||  ||||:|| 
Target 5' ggCTTTCCCTCCCTCCTTGc 3'
 956 - 975 150.00 -22.20
2 
miRNA  3' cgggAGGGG--ACUGAGGGACu 5'
              | |||   |:||||||| 
Target 5' gcagTGCCCAGGGGCTCCCTGc 3'
 2250 - 2271 150.00 -23.10
3 
miRNA  3' cgggagggGACU----GAGGGACu 5'
                  ||||    ||||||| 
Target 5' tgtgtgaaCTGAAATTCTCCCTGt 3'
 1930 - 1953 146.00 -15.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30524374 1 COSMIC
COSN26669641 8 COSMIC
COSN30107006 11 COSMIC
COSN30149139 14 COSMIC
COSN31506467 53 COSMIC
COSN26991538 59 COSMIC
COSN30149100 60 COSMIC
COSN30149097 62 COSMIC
COSN9701572 83 COSMIC
COSN30131562 84 COSMIC
COSN26991539 102 COSMIC
COSN20056488 106 COSMIC
COSN28183777 106 COSMIC
COSN31610778 118 COSMIC
COSN31494355 128 COSMIC
COSN26991540 133 COSMIC
COSN14377454 143 COSMIC
COSN30475594 209 COSMIC
COSN31594265 223 COSMIC
COSN31963120 798 COSMIC
COSN32062315 1462 COSMIC
COSN26844288 1700 COSMIC
COSN15660680 1760 COSMIC
COSN4944275 1809 COSMIC
COSN17075740 1894 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs550567089 6 dbSNP
rs754708795 8 dbSNP
rs577793635 9 dbSNP
rs760163451 10 dbSNP
rs371749209 11 dbSNP
rs1237310070 12 dbSNP
rs767468929 13 dbSNP
rs1234150225 14 dbSNP
rs532235008 20 dbSNP
rs774163471 28 dbSNP
rs747159156 30 dbSNP
rs367603006 31 dbSNP
rs908251020 36 dbSNP
rs142461806 37 dbSNP
rs371385939 38 dbSNP
rs747095554 41 dbSNP
rs773637891 43 dbSNP
rs772596490 44 dbSNP
rs202051555 46 dbSNP
rs1334007750 48 dbSNP
rs976164634 52 dbSNP
rs1236162668 56 dbSNP
rs966155676 58 dbSNP
rs919612061 59 dbSNP
rs1347945229 60 dbSNP
rs1349304201 73 dbSNP
rs975074402 79 dbSNP
rs1280386483 81 dbSNP
rs964920355 82 dbSNP
rs1399477203 83 dbSNP
rs1444395199 84 dbSNP
rs866491793 85 dbSNP
rs1373364948 86 dbSNP
rs540686650 99 dbSNP
rs952119408 100 dbSNP
rs988044952 101 dbSNP
rs1337484886 102 dbSNP
rs779801154 106 dbSNP
rs1257757742 109 dbSNP
rs1363825511 123 dbSNP
rs1456850298 128 dbSNP
rs1027588373 130 dbSNP
rs1032143066 133 dbSNP
rs528252435 134 dbSNP
rs758631514 139 dbSNP
rs1045579912 140 dbSNP
rs561170505 143 dbSNP
rs542347669 144 dbSNP
rs575456173 149 dbSNP
rs1422601663 154 dbSNP
rs1330783816 155 dbSNP
rs1053261058 168 dbSNP
rs78144311 169 dbSNP
rs1446641627 181 dbSNP
rs1300773323 190 dbSNP
rs1356988466 198 dbSNP
rs904157917 199 dbSNP
rs938481057 204 dbSNP
rs1043989910 205 dbSNP
rs886960072 211 dbSNP
rs1274317669 212 dbSNP
rs932180478 218 dbSNP
rs922174859 219 dbSNP
rs1187734615 232 dbSNP
rs1259626367 234 dbSNP
rs1486138170 235 dbSNP
rs1262265217 237 dbSNP
rs1486264835 237 dbSNP
rs976280492 238 dbSNP
rs869042636 239 dbSNP
rs944839701 239 dbSNP
rs942410528 245 dbSNP
rs545029136 248 dbSNP
rs1173348005 249 dbSNP
rs987751988 257 dbSNP
rs577575658 280 dbSNP
rs1415075216 290 dbSNP
rs907978114 296 dbSNP
rs983915764 305 dbSNP
rs1433309720 323 dbSNP
rs1271079031 324 dbSNP
rs1250350033 325 dbSNP
rs1227703124 327 dbSNP
rs1217938510 335 dbSNP
rs952089159 346 dbSNP
rs1291187903 353 dbSNP
rs1028029846 354 dbSNP
rs980123743 356 dbSNP
rs534680215 362 dbSNP
rs534545006 368 dbSNP
rs1242414547 371 dbSNP
rs1477671261 372 dbSNP
rs1031818610 375 dbSNP
rs1024164550 383 dbSNP
rs1396405179 388 dbSNP
rs1434795641 393 dbSNP
rs1157741808 401 dbSNP
rs1014064955 411 dbSNP
rs968781932 414 dbSNP
rs891607181 418 dbSNP
rs1021757079 424 dbSNP
rs1435005833 427 dbSNP
rs1031432680 430 dbSNP
rs113936496 432 dbSNP
rs1395859184 435 dbSNP
rs1000318820 437 dbSNP
rs1239501476 440 dbSNP
rs1283900640 446 dbSNP
rs1353115725 452 dbSNP
rs1205898790 453 dbSNP
rs750181770 455 dbSNP
rs146129773 456 dbSNP
rs932296561 461 dbSNP
rs781173088 465 dbSNP
rs1211815020 467 dbSNP
rs1254801238 471 dbSNP
rs1454619180 476 dbSNP
rs1177475772 477 dbSNP
rs900782401 478 dbSNP
rs1361519683 485 dbSNP
rs1470973058 508 dbSNP
rs1366975536 510 dbSNP
rs753250378 511 dbSNP
rs1460197029 516 dbSNP
rs1475750444 524 dbSNP
rs1395872748 530 dbSNP
rs887048392 532 dbSNP
rs555195124 533 dbSNP
rs1307212453 534 dbSNP
rs908004818 568 dbSNP
rs1337591105 569 dbSNP
rs983560073 577 dbSNP
rs930762868 582 dbSNP
rs898249185 592 dbSNP
rs920682447 593 dbSNP
rs1468888215 598 dbSNP
rs1197880913 601 dbSNP
rs980102913 602 dbSNP
rs1439009014 613 dbSNP
rs1182159560 614 dbSNP
rs970013639 615 dbSNP
rs867268217 616 dbSNP
rs536301840 622 dbSNP
rs1418976081 623 dbSNP
rs1465580195 625 dbSNP
rs1296925842 627 dbSNP
rs1392024896 634 dbSNP
rs912247416 635 dbSNP
rs76275377 636 dbSNP
rs190042691 637 dbSNP
rs1335215493 645 dbSNP
rs1031882211 646 dbSNP
rs1249537744 650 dbSNP
rs1340931176 655 dbSNP
rs1195881928 656 dbSNP
rs1254782825 661 dbSNP
rs1000028046 662 dbSNP
rs1189561436 665 dbSNP
rs904303430 666 dbSNP
rs552576953 667 dbSNP
rs1169030310 668 dbSNP
rs996534012 676 dbSNP
rs900811824 678 dbSNP
rs1040659531 682 dbSNP
rs538670792 695 dbSNP
rs1009117000 696 dbSNP
rs991584654 698 dbSNP
rs886691273 699 dbSNP
rs1381424204 701 dbSNP
rs1048396541 702 dbSNP
rs1328134816 710 dbSNP
rs930815750 714 dbSNP
rs920700746 715 dbSNP
rs1044434987 719 dbSNP
rs571644378 720 dbSNP
rs1264259016 721 dbSNP
rs1397142083 721 dbSNP
rs1157483740 725 dbSNP
rs548522273 741 dbSNP
rs1198751583 742 dbSNP
rs35590809 748 dbSNP
rs1003314858 760 dbSNP
rs951324236 769 dbSNP
rs948735153 770 dbSNP
rs1360143397 772 dbSNP
rs766779718 785 dbSNP
rs1364920158 786 dbSNP
rs917214046 804 dbSNP
rs1286932785 809 dbSNP
rs992707158 818 dbSNP
rs1181855194 825 dbSNP
rs1382757262 827 dbSNP
rs956188037 829 dbSNP
rs1302546031 830 dbSNP
rs924541340 837 dbSNP
rs979029203 841 dbSNP
rs1250679930 845 dbSNP
rs1026023678 851 dbSNP
rs1303414563 866 dbSNP
rs968560853 870 dbSNP
rs995263351 871 dbSNP
rs1213158131 875 dbSNP
rs1262921501 877 dbSNP
rs898344021 878 dbSNP
rs1209834375 883 dbSNP
rs1039403239 886 dbSNP
rs546561164 890 dbSNP
rs1028092109 894 dbSNP
rs3739497 908 dbSNP
rs773532216 909 dbSNP
rs560923392 912 dbSNP
rs1019332022 913 dbSNP
rs570006074 932 dbSNP
rs1454110007 937 dbSNP
rs1003874230 939 dbSNP
rs1392208824 942 dbSNP
rs1041999114 949 dbSNP
rs1326027286 955 dbSNP
rs1241197139 957 dbSNP
rs371756205 967 dbSNP
rs1047959114 974 dbSNP
rs1368882410 984 dbSNP
rs1302858934 985 dbSNP
rs772470098 986 dbSNP
rs1233070966 991 dbSNP
rs35867905 994 dbSNP
rs914763640 998 dbSNP
rs760411006 999 dbSNP
rs1044467363 1002 dbSNP
rs1479679758 1003 dbSNP
rs948767410 1007 dbSNP
rs917329061 1010 dbSNP
rs1409005605 1012 dbSNP
rs773930860 1014 dbSNP
rs1163987838 1024 dbSNP
rs1415336003 1028 dbSNP
rs530577082 1029 dbSNP
rs1462997348 1035 dbSNP
rs1165526466 1037 dbSNP
rs1316641283 1044 dbSNP
rs576744374 1064 dbSNP
rs934663277 1070 dbSNP
rs1386254948 1072 dbSNP
rs768371051 1074 dbSNP
rs748737195 1076 dbSNP
rs563384708 1077 dbSNP
rs968966659 1079 dbSNP
rs1172529965 1080 dbSNP
rs1337380772 1086 dbSNP
rs1454423141 1091 dbSNP
rs921062611 1092 dbSNP
rs779684232 1096 dbSNP
rs1190693571 1098 dbSNP
rs975243087 1104 dbSNP
rs965158969 1117 dbSNP
rs1446224403 1121 dbSNP
rs1485481147 1122 dbSNP
rs1262258761 1128 dbSNP
rs1255193551 1130 dbSNP
rs962623878 1131 dbSNP
rs564732695 1133 dbSNP
rs1006711034 1137 dbSNP
rs1408075037 1144 dbSNP
rs1345716814 1146 dbSNP
rs890877144 1151 dbSNP
rs1433767589 1152 dbSNP
rs544990765 1153 dbSNP
rs1004310266 1157 dbSNP
rs1029827461 1166 dbSNP
rs1415767211 1170 dbSNP
rs1269908544 1171 dbSNP
rs377116453 1172 dbSNP
rs999165860 1173 dbSNP
rs951057488 1175 dbSNP
rs1026994306 1176 dbSNP
rs1347208410 1176 dbSNP
rs947601363 1178 dbSNP
rs995065114 1183 dbSNP
rs899331986 1184 dbSNP
rs1241259925 1201 dbSNP
rs533342276 1203 dbSNP
rs1430388888 1204 dbSNP
rs1188179128 1211 dbSNP
rs937547405 1216 dbSNP
rs1023128424 1217 dbSNP
rs1453262174 1217 dbSNP
rs577688805 1218 dbSNP
rs371985714 1231 dbSNP
rs929966655 1232 dbSNP
rs1375415157 1233 dbSNP
rs918566374 1236 dbSNP
rs974071142 1241 dbSNP
rs1271287037 1242 dbSNP
rs1311696999 1248 dbSNP
rs962593061 1254 dbSNP
rs185916784 1257 dbSNP
rs1434818975 1264 dbSNP
rs1305629880 1265 dbSNP
rs985271214 1270 dbSNP
rs559343425 1271 dbSNP
rs769588246 1275 dbSNP
rs895931947 1284 dbSNP
rs1283352604 1285 dbSNP
rs540285333 1285 dbSNP
rs1057124156 1291 dbSNP
rs934674737 1294 dbSNP
rs1248552423 1298 dbSNP
rs540569795 1299 dbSNP
rs1191241044 1304 dbSNP
rs1474918180 1308 dbSNP
rs903152075 1309 dbSNP
rs1157604125 1310 dbSNP
rs1406330938 1320 dbSNP
rs1402797815 1331 dbSNP
rs1321577008 1339 dbSNP
rs745868343 1340 dbSNP
rs1043370872 1344 dbSNP
rs1195128435 1345 dbSNP
rs947366863 1353 dbSNP
rs1484634743 1355 dbSNP
rs921177128 1358 dbSNP
rs975272849 1371 dbSNP
rs573487125 1373 dbSNP
rs1277997805 1374 dbSNP
rs999700289 1379 dbSNP
rs554826847 1380 dbSNP
rs1256756637 1381 dbSNP
rs1467996428 1388 dbSNP
rs1211626807 1393 dbSNP
rs1211721700 1394 dbSNP
rs1486703522 1397 dbSNP
rs10608698 1401 dbSNP
rs769245695 1401 dbSNP
rs781301195 1406 dbSNP
rs772695404 1407 dbSNP
rs912334474 1412 dbSNP
rs536464968 1414 dbSNP
rs1230837625 1415 dbSNP
rs572052670 1416 dbSNP
rs557015328 1419 dbSNP
rs538783029 1426 dbSNP
rs951127345 1427 dbSNP
rs1460380056 1430 dbSNP
rs1167689937 1443 dbSNP
rs1026610630 1447 dbSNP
rs1355324753 1451 dbSNP
rs1390875725 1460 dbSNP
rs1294455806 1468 dbSNP
rs937494521 1474 dbSNP
rs1337757589 1476 dbSNP
rs1443143556 1481 dbSNP
rs367618048 1483 dbSNP
rs974142536 1488 dbSNP
rs35005659 1489 dbSNP
rs1414793265 1490 dbSNP
rs547017755 1496 dbSNP
rs907380051 1507 dbSNP
rs767360600 1509 dbSNP
rs1360382056 1514 dbSNP
rs1326350932 1534 dbSNP
rs534566863 1540 dbSNP
rs1356897806 1546 dbSNP
rs1194744597 1549 dbSNP
rs138402535 1556 dbSNP
rs1439212949 1557 dbSNP
rs1182420229 1560 dbSNP
rs549162394 1561 dbSNP
rs895963080 1562 dbSNP
rs1474427915 1565 dbSNP
rs1172503322 1576 dbSNP
rs1190769234 1577 dbSNP
rs1369560643 1582 dbSNP
rs1461862142 1585 dbSNP
rs530746795 1595 dbSNP
rs779218268 1596 dbSNP
rs761451785 1603 dbSNP
rs1398699263 1606 dbSNP
rs1417005756 1611 dbSNP
rs755284478 1616 dbSNP
rs974040152 1617 dbSNP
rs559079886 1633 dbSNP
rs1354649672 1640 dbSNP
rs1412719060 1641 dbSNP
rs753856692 1642 dbSNP
rs1231224634 1649 dbSNP
rs1341030573 1650 dbSNP
rs766518252 1653 dbSNP
rs144517721 1654 dbSNP
rs1340819895 1657 dbSNP
rs985793720 1666 dbSNP
rs901652584 1667 dbSNP
rs149271206 1668 dbSNP
rs1038897425 1671 dbSNP
rs564738893 1675 dbSNP
rs943245123 1677 dbSNP
rs1428494072 1685 dbSNP
rs374953089 1686 dbSNP
rs925173016 1689 dbSNP
rs943866245 1691 dbSNP
rs912365145 1693 dbSNP
rs541033465 1696 dbSNP
rs939311269 1698 dbSNP
rs982940843 1698 dbSNP
rs929781212 1700 dbSNP
rs919661874 1701 dbSNP
rs76585368 1702 dbSNP
rs1002214166 1705 dbSNP
rs1381617457 1710 dbSNP
rs1293341826 1711 dbSNP
rs907478354 1712 dbSNP
rs1440881699 1715 dbSNP
rs1301979169 1721 dbSNP
rs1046310264 1722 dbSNP
rs969006150 1723 dbSNP
rs897204993 1733 dbSNP
rs750894400 1736 dbSNP
rs1203955495 1742 dbSNP
rs1043685086 1751 dbSNP
rs991671013 1755 dbSNP
rs1465694156 1759 dbSNP
rs1459618265 1764 dbSNP
rs1393297417 1765 dbSNP
rs1455782849 1777 dbSNP
rs1393455555 1782 dbSNP
rs1165439687 1785 dbSNP
rs1406985886 1805 dbSNP
rs1038425163 1809 dbSNP
rs960202599 1813 dbSNP
rs1286841519 1819 dbSNP
rs77171485 1820 dbSNP
rs1176643650 1824 dbSNP
rs1470559095 1835 dbSNP
rs1390750133 1839 dbSNP
rs941335652 1843 dbSNP
rs1324661122 1844 dbSNP
rs1240183092 1849 dbSNP
rs1191978098 1850 dbSNP
rs911240509 1856 dbSNP
rs768020179 1862 dbSNP
rs763417823 1864 dbSNP
rs1274177932 1877 dbSNP
rs1049775340 1879 dbSNP
rs933888900 1888 dbSNP
rs561268575 1892 dbSNP
rs1270373552 1893 dbSNP
rs999423785 1894 dbSNP
rs978327799 1895 dbSNP
rs966538556 1897 dbSNP
rs1192050493 1906 dbSNP
rs1417485758 1909 dbSNP
rs542943990 1910 dbSNP
rs1222649090 1916 dbSNP
rs1156705566 1919 dbSNP
rs967520143 1920 dbSNP
rs575418736 1925 dbSNP
rs1350771628 1938 dbSNP
rs1164124793 1946 dbSNP
rs1022109230 1948 dbSNP
rs1391723562 1954 dbSNP
rs1438007347 1956 dbSNP
rs914961670 1957 dbSNP
rs557172747 1958 dbSNP
rs959005878 1967 dbSNP
rs1438230607 1974 dbSNP
rs774757761 1976 dbSNP
rs537311870 1978 dbSNP
rs1233279345 1982 dbSNP
rs1271807674 1983 dbSNP
rs1003241921 1987 dbSNP
rs1438373251 2004 dbSNP
rs1222403704 2011 dbSNP
rs1479792837 2016 dbSNP
rs1343298967 2018 dbSNP
rs112086050 2032 dbSNP
rs1253792584 2034 dbSNP
rs1472788870 2050 dbSNP
rs1401278951 2055 dbSNP
rs776662601 2056 dbSNP
rs1406980656 2061 dbSNP
rs1171908324 2064 dbSNP
rs1039651810 2067 dbSNP
rs1008107490 2068 dbSNP
rs1460184410 2069 dbSNP
rs1253904707 2070 dbSNP
rs891045315 2076 dbSNP
rs1193239791 2080 dbSNP
rs751757777 2095 dbSNP
rs1414562666 2100 dbSNP
rs994261701 2102 dbSNP
rs1229343055 2108 dbSNP
rs1046925650 2112 dbSNP
rs578052039 2114 dbSNP
rs897340906 2133 dbSNP
rs1207635708 2135 dbSNP
rs1038393822 2136 dbSNP
rs929786527 2140 dbSNP
rs1209930386 2146 dbSNP
rs889897302 2148 dbSNP
rs1241978957 2157 dbSNP
rs1473766680 2161 dbSNP
rs1182349326 2164 dbSNP
rs919708164 2165 dbSNP
rs1418247568 2178 dbSNP
rs1426204403 2179 dbSNP
rs113972469 2183 dbSNP
rs1370789838 2187 dbSNP
rs1287497945 2194 dbSNP
rs1433669825 2196 dbSNP
rs947735225 2199 dbSNP
rs1231479087 2201 dbSNP
rs943851 2203 dbSNP
rs567417392 2205 dbSNP
rs1303704313 2211 dbSNP
rs1288784058 2212 dbSNP
rs1220672536 2218 dbSNP
rs1359596885 2225 dbSNP
rs112457411 2242 dbSNP
rs960316530 2243 dbSNP
rs1042317637 2252 dbSNP
rs945163999 2254 dbSNP
rs915099032 2259 dbSNP
rs989339359 2263 dbSNP
rs1443929278 2264 dbSNP
rs1210797017 2272 dbSNP
rs937733363 2280 dbSNP
rs1463435277 2282 dbSNP
rs1189973007 2283 dbSNP
rs1390201866 2287 dbSNP
rs1311102634 2290 dbSNP
rs926430185 2292 dbSNP
rs372125010 2295 dbSNP
rs1415417986 2301 dbSNP
rs928870207 2311 dbSNP
rs554341555 2312 dbSNP
rs977641771 2313 dbSNP
rs188846704 2317 dbSNP
rs967927480 2321 dbSNP
rs1178516012 2326 dbSNP
rs1427033962 2327 dbSNP
rs1370302651 2329 dbSNP
rs1021726074 2331 dbSNP
rs1276811158 2352 dbSNP
rs1187509730 2365 dbSNP
rs1345904039 2365 dbSNP
rs1283243653 2368 dbSNP
rs1489532570 2372 dbSNP
rs1256045606 2374 dbSNP
rs569864755 2378 dbSNP
rs1467637259 2379 dbSNP
rs1485061267 2382 dbSNP
rs551607411 2387 dbSNP
rs774840782 2388 dbSNP
rs1018326514 2394 dbSNP
rs1008223537 2395 dbSNP
rs747268867 2398 dbSNP
rs777789449 2399 dbSNP
rs1160542038 2402 dbSNP
rs748593152 2404 dbSNP
rs1403693682 2405 dbSNP
rs532850424 2407 dbSNP
rs1047400974 2408 dbSNP
rs1414180329 2409 dbSNP
rs994032214 2411 dbSNP
rs898292384 2412 dbSNP
rs138384300 2415 dbSNP
rs113678985 2416 dbSNP
rs889866907 2416 dbSNP
rs528859114 2418 dbSNP
rs998560237 2419 dbSNP
rs371937316 2420 dbSNP
rs1291340143 2427 dbSNP
rs1451870864 2431 dbSNP
rs1042307161 2442 dbSNP
rs538875534 2444 dbSNP
rs1473766940 2446 dbSNP
rs939004733 2447 dbSNP
rs928921962 2449 dbSNP
rs978049352 2450 dbSNP
rs111601334 2451 dbSNP
rs150077615 2461 dbSNP
rs367735933 2462 dbSNP
rs563492896 2468 dbSNP
rs981896914 2470 dbSNP
rs1411434771 2471 dbSNP
rs1250514402 2481 dbSNP
rs1354765775 2483 dbSNP
rs758862261 2486 dbSNP
rs1242488140 2488 dbSNP
rs374459260 2491 dbSNP
rs1475853159 2495 dbSNP
rs1194927383 2496 dbSNP
rs1256213639 2505 dbSNP
rs1201713833 2506 dbSNP
rs745401599 2507 dbSNP
rs1483796191 2510 dbSNP
rs1250437384 2511 dbSNP
rs1190185372 2512 dbSNP
rs748506805 2512 dbSNP
rs4376536 2513 dbSNP
rs6879 2514 dbSNP
rs954246466 2514 dbSNP
rs1336072365 2515 dbSNP
rs386739000 2515 dbSNP
rs998300808 2516 dbSNP
rs576611736 2517 dbSNP
rs1482479620 2518 dbSNP
rs986822949 2518 dbSNP
rs553451679 2519 dbSNP
rs541193744 2520 dbSNP
rs1295406880 2521 dbSNP
rs1314890249 2522 dbSNP
rs1389764730 2526 dbSNP
rs574065039 2528 dbSNP
rs1025571529 2535 dbSNP
rs1173242760 2543 dbSNP
rs1298961446 2544 dbSNP
rs937812505 2545 dbSNP
rs1392720110 2559 dbSNP
rs370566576 2560 dbSNP
rs994455610 2569 dbSNP
rs1046681937 2570 dbSNP
rs1434220255 2580 dbSNP
rs898329023 2581 dbSNP
rs1016759451 2582 dbSNP
rs542233732 2586 dbSNP
rs1370736342 2593 dbSNP
rs555846830 2594 dbSNP
rs1188964963 2601 dbSNP
rs894924053 2603 dbSNP
rs1056118502 2607 dbSNP
rs939044666 2611 dbSNP
rs902143875 2612 dbSNP
rs1035984381 2613 dbSNP
rs1041977459 2619 dbSNP
rs941703265 2620 dbSNP
rs946329165 2629 dbSNP
rs914817691 2636 dbSNP
rs990343332 2637 dbSNP
rs910104301 2641 dbSNP
rs1265536512 2645 dbSNP
rs1178865746 2655 dbSNP
rs942824532 2672 dbSNP
rs1458860853 2678 dbSNP
rs1200767683 2681 dbSNP
rs984352091 2688 dbSNP
rs1250887089 2691 dbSNP
rs954332170 2699 dbSNP
rs1356900991 2700 dbSNP
rs1390280132 2703 dbSNP
rs1457323606 2704 dbSNP
rs921426684 2713 dbSNP
rs1365078554 2723 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cggGAGGGGACUGAGGGACu 5'
             |||::|   :|||||| 
Target 5' ---CUCUUCACCUUCCCUG- 3'
 		1 - 16
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000372189.3 | 3UTR | CUCUUCACCUUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
146 hsa-miR-4270 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT056076 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 2 2
MIRT057833 SLC30A7 solute carrier family 30 member 7 2 2
MIRT109295 TXLNG taxilin gamma 2 2
MIRT117521 MIDN midnolin 2 2
MIRT183504 BTG2 BTG anti-proliferation factor 2 2 2
MIRT258346 HOXA11 homeobox A11 2 6
MIRT275743 TFDP1 transcription factor Dp-1 2 2
MIRT284426 CAPN15 calpain 15 2 2
MIRT386430 CCL22 C-C motif chemokine ligand 22 2 2
MIRT443374 PLXNA2 plexin A2 2 2
MIRT445251 SEMA5A semaphorin 5A 2 2
MIRT445767 CCND3 cyclin D3 2 2
MIRT447231 ABI2 abl interactor 2 2 2
MIRT451224 ZNF444 zinc finger protein 444 2 2
MIRT451433 TJP3 tight junction protein 3 2 4
MIRT451959 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452006 FKBP5 FK506 binding protein 5 2 2
MIRT452300 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT452717 DTHD1 death domain containing 1 2 2
MIRT453361 ZNF3 zinc finger protein 3 2 2
MIRT453458 GLG1 golgi glycoprotein 1 2 2
MIRT453832 SAA1 serum amyloid A1 2 2
MIRT453928 COMMD5 COMM domain containing 5 2 4
MIRT454312 ZNF134 zinc finger protein 134 2 2
MIRT454493 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454836 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT455142 TBC1D25 TBC1 domain family member 25 2 2
MIRT455922 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT456163 TTF2 transcription termination factor 2 2 2
MIRT456395 KLHL12 kelch like family member 12 2 2
MIRT456786 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT457164 MXRA7 matrix remodeling associated 7 2 2
MIRT457190 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT457415 RPL36 ribosomal protein L36 2 2
MIRT457630 UPK3BL uroplakin 3B like 1 2 2
MIRT458720 VPS39 VPS39, HOPS complex subunit 2 2
MIRT458745 CES2 carboxylesterase 2 2 2
MIRT459269 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT459490 CCL11 C-C motif chemokine ligand 11 2 2
MIRT460319 SH3RF1 SH3 domain containing ring finger 1 2 2
MIRT461005 SYT7 synaptotagmin 7 2 2
MIRT461579 SCO1 SCO1, cytochrome c oxidase assembly protein 2 4
MIRT461820 SNAP23 synaptosome associated protein 23 2 2
MIRT463332 ZFHX3 zinc finger homeobox 3 2 2
MIRT463449 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464272 VCL vinculin 2 2
MIRT464895 UBALD1 UBA like domain containing 1 2 2
MIRT465556 TOB2 transducer of ERBB2, 2 2 2
MIRT466360 THBS1 thrombospondin 1 2 2
MIRT466956 STAT3 signal transducer and activator of transcription 3 2 2
MIRT467321 SPATA2 spermatogenesis associated 2 2 2
MIRT467440 SND1 staphylococcal nuclease and tudor domain containing 1 2 2
MIRT467823 SLC29A2 solute carrier family 29 member 2 2 2
MIRT471173 PHB2 prohibitin 2 2 2
MIRT471397 PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2 2
MIRT471754 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 2
MIRT471846 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT472020 NPTXR neuronal pentraxin receptor 2 2
MIRT472224 NGFR nerve growth factor receptor 2 2
MIRT472439 NBL1 neuroblastoma 1, DAN family BMP antagonist 2 2
MIRT472541 NACC1 nucleus accumbens associated 1 2 2
MIRT473195 MINOS1-NBL1 MINOS1-NBL1 readthrough 2 2
MIRT473211 MINK1 misshapen like kinase 1 2 2
MIRT473668 MARCKSL1 MARCKS like 1 2 2
MIRT474852 KHSRP KH-type splicing regulatory protein 2 2
MIRT474939 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT477330 EPHA2 EPH receptor A2 2 2
MIRT477395 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT477466 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT477974 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 2 2
MIRT478331 DDN dendrin 2 2
MIRT479481 CDK2 cyclin dependent kinase 2 2 2
MIRT481212 ATXN7L3B ataxin 7 like 3B 2 2
MIRT481263 ATXN7L3 ataxin 7 like 3 2 2
MIRT481409 ASXL1 additional sex combs like 1, transcriptional regulator 2 2
MIRT482051 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT482396 AEN apoptosis enhancing nuclease 2 2
MIRT483160 PCSK2 proprotein convertase subtilisin/kexin type 2 2 7
MIRT483370 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT483520 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 4
MIRT484059 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT487075 CLASP1 cytoplasmic linker associated protein 1 2 4
MIRT487421 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT488359 PAX2 paired box 2 2 2
MIRT488592 ST7L suppression of tumorigenicity 7 like 2 2
MIRT489556 SOX11 SRY-box 11 2 4
MIRT489804 KRT80 keratin 80 2 4
MIRT489865 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 2 2
MIRT490014 KIFC2 kinesin family member C2 2 2
MIRT490036 PCSK4 proprotein convertase subtilisin/kexin type 4 2 2
MIRT491070 ACVR1B activin A receptor type 1B 2 2
MIRT494016 DUSP9 dual specificity phosphatase 9 2 2
MIRT494816 AKAP11 A-kinase anchoring protein 11 2 2
MIRT495991 LTBP2 latent transforming growth factor beta binding protein 2 2 2
MIRT496272 SLC2A13 solute carrier family 2 member 13 2 2
MIRT500454 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT507989 BCL2L13 BCL2 like 13 2 4
MIRT509713 ANKRD23 ankyrin repeat domain 23 2 2
MIRT527984 TSLP thymic stromal lymphopoietin 2 2
MIRT530448 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT531235 FANCC Fanconi anemia complementation group C 2 2
MIRT534590 RPL28 ribosomal protein L28 2 2
MIRT535990 MED28 mediator complex subunit 28 2 4
MIRT537280 GABRA5 gamma-aminobutyric acid type A receptor alpha5 subunit 2 2
MIRT539924 DUSP28 dual specificity phosphatase 28 2 2
MIRT554711 RNF146 ring finger protein 146 2 2
MIRT558962 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT568497 ARHGDIA Rho GDP dissociation inhibitor alpha 2 2
MIRT568875 LY6H lymphocyte antigen 6 family member H 2 2
MIRT568987 CACNA1C calcium voltage-gated channel subunit alpha1 C 2 2
MIRT569990 TMEM184A transmembrane protein 184A 2 2
MIRT570485 THRA thyroid hormone receptor, alpha 2 2
MIRT572826 MYO1C myosin IC 2 2
MIRT608199 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT613220 CCDC85C coiled-coil domain containing 85C 2 4
MIRT629782 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT635332 RASSF4 Ras association domain family member 4 2 2
MIRT653632 SLC30A3 solute carrier family 30 member 3 2 2
MIRT664572 GUF1 GUF1 homolog, GTPase 2 2
MIRT667855 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668820 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT671274 ETFDH electron transfer flavoprotein dehydrogenase 2 2
MIRT681448 CIITA class II major histocompatibility complex transactivator 2 2
MIRT684817 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT685861 ANGEL1 angel homolog 1 2 2
MIRT688812 CAPZB capping actin protein of muscle Z-line beta subunit 2 2
MIRT691198 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT696947 CERK ceramide kinase 2 2
MIRT699741 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT701259 NUP35 nucleoporin 35 2 2
MIRT701935 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT703332 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT705519 ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 2 2
MIRT706065 PKD1 polycystin 1, transient receptor potential channel interacting 2 2
MIRT713238 SV2B synaptic vesicle glycoprotein 2B 2 2
MIRT714670 CHRNE cholinergic receptor nicotinic epsilon subunit 2 2
MIRT715001 TSPAN11 tetraspanin 11 2 2
MIRT715356 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT715971 FADS3 fatty acid desaturase 3 2 2
MIRT719585 FNBP4 formin binding protein 4 2 2
MIRT719667 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT723360 ASCL2 achaete-scute family bHLH transcription factor 2 2 2
MIRT734985 GADD45A growth arrest and DNA damage inducible alpha 2 0
MIRT735022 MMP19 matrix metallopeptidase 19 3 0
MIRT737359 SATB2 SATB homeobox 2 3 0
MIRT756223 MCM3 minichromosome maintenance complex component 3 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miR-4270 Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4270 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4270 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (total RNA)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-4270 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4270 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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