miRTarBase - #MIRT456010


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pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol CYP2C19   
Synonyms CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
Description cytochrome P450 family 2 subfamily C member 19
Transcript NM_000769   
Expression
Putative miRNA Targets on CYP2C19
3'UTR of CYP2C19
(miRNA target sites are highlighted)		 
>CYP2C19|NM_000769|3'UTR
   1 AGAAGCACAGATGGTCTGGCTGCTCCTGTGCTGTCCCTGCAGCTCTCTTTCCTCTGGTCCAAATTTCACTATCTGTGATG
  81 CTTCTTCTGACCCGTCATCTCACATTTTCCCTTCCCCCAAGATCTAGTGAACATTCAGCCTCCATTAAAAAAGTTTCACT
 161 GTGCAAATATATCTGCTATTCCCCATACTCTATAATAGTTACATTGAGTGCCACATAATGCTGATACTTGTCTAATGTTG
 241 AGTTATTAACATATTATTATTAAATAGAGAAAGATGATTTGTGTATTATAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aguGGUAACGAUUU--------CACGUUaa 5'
             |||||   |||        ||||||  
Target 5' cctCCATTAAAAAAGTTTCACTGTGCAAat 3'
 139 - 168 129.00 -7.90
2 
miRNA  3' agUG-GUAACGAUU-U---CACGUUAa 5'
            || :| ||||:| |   || :||| 
Target 5' ccACATAATGCTGATACTTGTCTAATg 3'
 211 - 237 108.00 -6.60
3 
miRNA  3' agUGGUAACGAU----UUCACGUUaa 5'
            |: || |:||    :||||| |  
Target 5' ctATAATAGTTACATTGAGTGCCAca 3'
 190 - 215 106.00 -7.36
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
633853 1 ClinVar
COSN24806195 63 COSMIC
COSN15661618 74 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs55640102 1 dbSNP
rs1205366931 4 dbSNP
rs917744994 6 dbSNP
rs1422050899 10 dbSNP
rs768868902 11 dbSNP
rs776650550 12 dbSNP
rs1386785916 14 dbSNP
rs761974458 21 dbSNP
rs372981761 22 dbSNP
rs1327948685 23 dbSNP
rs376249059 26 dbSNP
rs930592061 30 dbSNP
rs1309685184 31 dbSNP
rs201538336 37 dbSNP
rs1034187993 38 dbSNP
rs766264584 41 dbSNP
rs751415691 42 dbSNP
rs754612888 43 dbSNP
rs775549674 43 dbSNP
rs767312957 46 dbSNP
rs376246464 53 dbSNP
rs770049654 59 dbSNP
rs908156351 63 dbSNP
rs1181518919 72 dbSNP
rs940942188 73 dbSNP
rs1376286964 74 dbSNP
rs776343249 78 dbSNP
rs531145534 79 dbSNP
rs1437409863 82 dbSNP
rs17882796 83 dbSNP
rs995894104 87 dbSNP
rs1365818609 92 dbSNP
rs775981161 94 dbSNP
rs564554316 95 dbSNP
rs41317284 102 dbSNP
rs925515852 111 dbSNP
rs764867845 112 dbSNP
rs903529348 119 dbSNP
rs1239479217 123 dbSNP
rs1000977542 127 dbSNP
rs1352142098 130 dbSNP
rs1291016686 133 dbSNP
rs1197325538 142 dbSNP
rs1413813310 144 dbSNP
rs936857695 152 dbSNP
rs1335616294 157 dbSNP
rs974906864 167 dbSNP
rs1158535701 172 dbSNP
rs1255555477 174 dbSNP
rs139900656 175 dbSNP
rs544997836 176 dbSNP
rs932459484 184 dbSNP
rs1051273017 193 dbSNP
rs1258569651 198 dbSNP
rs956865026 200 dbSNP
rs1189695014 204 dbSNP
rs1013484138 226 dbSNP
rs1025245798 228 dbSNP
rs1248076513 233 dbSNP
rs1205679531 237 dbSNP
rs1476873579 240 dbSNP
rs969177240 245 dbSNP
rs939642210 246 dbSNP
rs1232525719 247 dbSNP
rs762568352 250 dbSNP
rs1285642989 252 dbSNP
rs1467078045 256 dbSNP
rs1428000662 258 dbSNP
rs1168487712 260 dbSNP
rs1325376222 261 dbSNP
rs927400682 263 dbSNP
rs566634257 265 dbSNP
rs1436478885 266 dbSNP
rs898381879 271 dbSNP
rs985227494 272 dbSNP
rs1461307836 274 dbSNP
rs1348353803 275 dbSNP
rs907853747 281 dbSNP
rs1241620588 284 dbSNP
rs940960423 284 dbSNP
rs756372031 285 dbSNP
rs1279182968 289 dbSNP
rs1431561627 294 dbSNP
rs28399515 300 dbSNP
rs1217226836 301 dbSNP
rs529255914 309 dbSNP
rs1013701497 310 dbSNP
rs1278096693 313 dbSNP
rs143414928 325 dbSNP
rs549225840 331 dbSNP
rs1338107199 332 dbSNP
rs932111439 333 dbSNP
rs569156004 344 dbSNP
rs966701206 347 dbSNP
rs1367964882 353 dbSNP
rs1291403654 361 dbSNP
rs1324533040 362 dbSNP
rs1397054659 372 dbSNP
rs185030154 373 dbSNP
rs200806928 375 dbSNP
rs1325723003 376 dbSNP
rs1408445790 378 dbSNP
rs903643995 383 dbSNP
rs1478663991 384 dbSNP
rs1169285668 387 dbSNP
rs1191299898 392 dbSNP
rs936420705 392 dbSNP
rs1451461300 398 dbSNP
rs1393156912 399 dbSNP
rs1052554242 401 dbSNP
rs187840370 402 dbSNP
rs1473123947 406 dbSNP
rs892105298 408 dbSNP
rs1201915053 411 dbSNP
rs1436854784 415 dbSNP
rs1273347908 418 dbSNP
rs1229951601 423 dbSNP
rs577576114 428 dbSNP
rs748874211 429 dbSNP
rs1404945103 436 dbSNP
rs1276978359 438 dbSNP
rs1354136295 439 dbSNP
rs191493794 439 dbSNP
rs1002072182 440 dbSNP
rs115596637 441 dbSNP
rs767900850 449 dbSNP
rs542613929 454 dbSNP
rs1341517917 455 dbSNP
rs1433703713 456 dbSNP
rs1427262280 457 dbSNP
rs184350496 461 dbSNP
rs939675478 462 dbSNP
rs1247648538 465 dbSNP
rs1285403868 468 dbSNP
rs1036659736 475 dbSNP
rs1484378185 482 dbSNP
rs1279011824 490 dbSNP
rs879735269 499 dbSNP
rs573431385 500 dbSNP
rs1286260117 505 dbSNP
rs1222392822 510 dbSNP
rs542004573 520 dbSNP
rs1373092306 526 dbSNP
rs898159631 537 dbSNP
rs1411909607 540 dbSNP
rs1353566973 543 dbSNP
rs1214174295 544 dbSNP
rs74154115 550 dbSNP
rs1360807960 552 dbSNP
rs564986389 555 dbSNP
rs962034814 556 dbSNP
rs879849755 558 dbSNP
rs1189574079 561 dbSNP
rs1183823556 565 dbSNP
rs146750273 568 dbSNP
rs895004363 580 dbSNP
rs923561666 584 dbSNP
rs1483969236 585 dbSNP
rs148915656 592 dbSNP
rs569293767 594 dbSNP
rs986290374 596 dbSNP
rs1328843040 597 dbSNP
rs756353216 604 dbSNP
rs1418100568 605 dbSNP
rs1269163526 619 dbSNP
rs1230692632 620 dbSNP
rs1377072581 622 dbSNP
rs1332939940 624 dbSNP
rs925437211 625 dbSNP
rs1158354765 630 dbSNP
rs1403389104 632 dbSNP
rs1168917230 634 dbSNP
rs1416688550 634 dbSNP
rs1459734074 634 dbSNP
rs34415420 634 dbSNP
rs66722555 634 dbSNP
rs1165077911 635 dbSNP
rs1398268046 639 dbSNP
rs1332739644 640 dbSNP
rs78523157 649 dbSNP
rs936434729 650 dbSNP
rs1025071067 651 dbSNP
rs1424199564 652 dbSNP
rs370284572 653 dbSNP
rs1249251177 655 dbSNP
rs1210943679 656 dbSNP
rs1333202898 657 dbSNP
rs1309438684 659 dbSNP
rs1355323601 661 dbSNP
rs1237537288 664 dbSNP
rs1265045944 675 dbSNP
rs1245833975 676 dbSNP
rs1259887912 695 dbSNP
rs564279939 697 dbSNP
rs1202014859 701 dbSNP
rs575542141 702 dbSNP
rs949122002 703 dbSNP
rs189585645 706 dbSNP
rs1179257303 708 dbSNP
rs1393482422 710 dbSNP
rs1240112923 711 dbSNP
rs1046089102 712 dbSNP
rs1178296253 714 dbSNP
rs1378471690 717 dbSNP
rs1371048382 718 dbSNP
rs905139580 719 dbSNP
rs1002104889 720 dbSNP
rs1171252539 725 dbSNP
rs1026841145 727 dbSNP
rs560547920 729 dbSNP
rs1466606485 730 dbSNP
rs975044288 731 dbSNP
rs1467383160 734 dbSNP
rs181126191 737 dbSNP
rs1223079067 745 dbSNP
rs954911294 751 dbSNP
rs755050246 752 dbSNP
rs1014968762 753 dbSNP
rs150921324 755 dbSNP
rs544410861 759 dbSNP
rs988008709 767 dbSNP
rs976086311 768 dbSNP
rs1343015720 769 dbSNP
rs1232008295 774 dbSNP
rs1299667179 774 dbSNP
rs569120975 779 dbSNP
rs953653590 780 dbSNP
rs1254030308 781 dbSNP
rs1393843396 785 dbSNP
rs986322065 788 dbSNP
rs1371895922 789 dbSNP
rs1199213627 790 dbSNP
rs140714248 795 dbSNP
rs145839468 796 dbSNP
rs1435332197 799 dbSNP
rs571128110 799 dbSNP
rs1055069978 800 dbSNP
rs533758565 802 dbSNP
rs1435200460 808 dbSNP
rs1197121964 815 dbSNP
rs1429044906 819 dbSNP
rs1208905887 820 dbSNP
rs1344196736 821 dbSNP
rs1478411817 822 dbSNP
rs770818009 824 dbSNP
rs1173419631 826 dbSNP
rs1333795472 828 dbSNP
rs1287271481 830 dbSNP
rs949256982 833 dbSNP
rs1398800070 843 dbSNP
rs1463593054 865 dbSNP
rs1413470486 866 dbSNP
rs949144809 868 dbSNP
rs553384741 877 dbSNP
rs879700448 880 dbSNP
rs1053788073 882 dbSNP
rs1046121970 886 dbSNP
rs1473038408 888 dbSNP
rs926256137 889 dbSNP
rs1388162123 898 dbSNP
rs1298852581 899 dbSNP
rs567010370 901 dbSNP
rs1336621178 902 dbSNP
rs996551251 906 dbSNP
rs1219057023 908 dbSNP
rs1279995966 913 dbSNP
rs1256719618 915 dbSNP
rs1316056528 918 dbSNP
rs1029253017 919 dbSNP
rs1267266541 922 dbSNP
rs937926131 927 dbSNP
rs535987184 932 dbSNP
rs1009148573 937 dbSNP
rs1015134851 940 dbSNP
rs1266116857 944 dbSNP
rs1489555380 948 dbSNP
rs1208310858 953 dbSNP
rs1340585597 955 dbSNP
rs1335375369 962 dbSNP
rs1398308506 965 dbSNP
rs1387177765 969 dbSNP
rs1048308960 970 dbSNP
rs888277747 973 dbSNP
rs1458137299 978 dbSNP
rs1414422292 979 dbSNP
rs1161707686 981 dbSNP
rs1488808824 984 dbSNP
rs1004087322 993 dbSNP
rs1196366166 994 dbSNP
rs1189455562 995 dbSNP
rs555491544 997 dbSNP
rs1037262396 1000 dbSNP
rs1247410423 1012 dbSNP
rs755517905 1021 dbSNP
rs1209098696 1022 dbSNP
rs897936386 1028 dbSNP
rs1466119601 1032 dbSNP
rs997537574 1033 dbSNP
rs1270840172 1035 dbSNP
rs575806744 1036 dbSNP
rs953350727 1038 dbSNP
rs1285443360 1046 dbSNP
rs1169062383 1051 dbSNP
rs773962100 1054 dbSNP
rs781038557 1055 dbSNP
rs1007772803 1057 dbSNP
rs1320516229 1065 dbSNP
rs1459082507 1065 dbSNP
rs1436222442 1070 dbSNP
rs561101082 1071 dbSNP
rs1321766853 1072 dbSNP
rs952426662 1073 dbSNP
rs1414885546 1074 dbSNP
rs990858918 1080 dbSNP
rs1447786790 1083 dbSNP
rs958524312 1089 dbSNP
rs375305970 1091 dbSNP
rs529385393 1092 dbSNP
rs761432652 1100 dbSNP
rs868567736 1100 dbSNP
rs1364630913 1105 dbSNP
rs865835864 1105 dbSNP
rs558500150 1107 dbSNP
rs1046293903 1112 dbSNP
rs1193535584 1112 dbSNP
rs1451807443 1112 dbSNP
rs970485822 1116 dbSNP
rs1340878879 1122 dbSNP
rs544547492 1123 dbSNP
rs745710610 1124 dbSNP
rs1213932880 1127 dbSNP
rs1367717132 1129 dbSNP
rs935140186 1131 dbSNP
rs1313469883 1140 dbSNP
rs769431552 1142 dbSNP
rs926287276 1146 dbSNP
rs937623527 1147 dbSNP
rs1048085949 1158 dbSNP
rs893847199 1162 dbSNP
rs138737125 1168 dbSNP
rs939918322 1169 dbSNP
rs1036889415 1170 dbSNP
rs1009182215 1174 dbSNP
rs900977492 1175 dbSNP
rs184709061 1181 dbSNP
rs540617161 1188 dbSNP
rs143377860 1189 dbSNP
rs372131538 1189 dbSNP
rs754843583 1189 dbSNP
rs994976208 1191 dbSNP
rs1179592443 1192 dbSNP
rs1026744278 1205 dbSNP
rs1274741092 1208 dbSNP
rs1258929698 1213 dbSNP
rs1425022973 1218 dbSNP
rs952531077 1219 dbSNP
rs559903744 1220 dbSNP
rs1231242060 1222 dbSNP
rs1384221355 1224 dbSNP
rs528437476 1225 dbSNP
rs889117388 1226 dbSNP
rs1419936656 1227 dbSNP
rs1007549243 1229 dbSNP
rs1431755704 1239 dbSNP
rs1357326950 1243 dbSNP
rs1032744643 1245 dbSNP
rs762513097 1249 dbSNP
rs529403668 1251 dbSNP
rs768304794 1252 dbSNP
rs1472059305 1258 dbSNP
rs551758379 1259 dbSNP
rs1183693200 1263 dbSNP
rs570646875 1264 dbSNP
rs142519224 1265 dbSNP
rs989232423 1267 dbSNP
rs1354607765 1269 dbSNP
rs1313090831 1280 dbSNP
rs915075530 1282 dbSNP
rs932091509 1284 dbSNP
rs1328725604 1285 dbSNP
rs1050519882 1286 dbSNP
rs890475340 1287 dbSNP
rs981862257 1294 dbSNP
rs1316663657 1296 dbSNP
rs926397048 1297 dbSNP
rs762350184 1298 dbSNP
rs1211328765 1306 dbSNP
rs1302132261 1310 dbSNP
rs1036628670 1312 dbSNP
rs1258276871 1312 dbSNP
rs553312473 1316 dbSNP
rs1456554015 1324 dbSNP
rs1482602752 1328 dbSNP
rs562508979 1329 dbSNP
rs1421495828 1330 dbSNP
rs1242004219 1337 dbSNP
rs189119944 1343 dbSNP
rs1245559555 1344 dbSNP
rs1464751231 1347 dbSNP
rs995007209 1348 dbSNP
rs1241466599 1350 dbSNP
rs909519096 1352 dbSNP
rs1405393499 1353 dbSNP
rs1028279905 1358 dbSNP
rs1312085933 1370 dbSNP
rs1229023466 1377 dbSNP
rs894636611 1380 dbSNP
rs939971414 1381 dbSNP
rs1434037693 1386 dbSNP
rs1389140054 1392 dbSNP
rs1322073734 1393 dbSNP
rs551314604 1397 dbSNP
rs1456071308 1399 dbSNP
rs571502628 1400 dbSNP
rs1349015306 1401 dbSNP
rs1164834026 1403 dbSNP
rs1425077014 1404 dbSNP
rs1387582719 1410 dbSNP
rs970378570 1412 dbSNP
rs555312373 1418 dbSNP
rs574438658 1423 dbSNP
rs964291981 1426 dbSNP
rs922468857 1430 dbSNP
rs933786426 1431 dbSNP
rs1222359568 1433 dbSNP
rs1049543456 1434 dbSNP
rs527627538 1435 dbSNP
rs17882302 1443 dbSNP
rs989348179 1449 dbSNP
rs1384909866 1453 dbSNP
rs1468177624 1454 dbSNP
rs1336103193 1458 dbSNP
rs915087188 1462 dbSNP
rs1377781391 1463 dbSNP
rs1449137338 1482 dbSNP
rs1293778635 1489 dbSNP
rs943439680 1490 dbSNP
rs1368180115 1493 dbSNP
rs1277985122 1497 dbSNP
rs1429667969 1500 dbSNP
rs986638736 1506 dbSNP
rs1220177993 1507 dbSNP
rs911952705 1509 dbSNP
rs566923364 1510 dbSNP
rs1431843564 1513 dbSNP
rs944697306 1514 dbSNP
rs1192017875 1521 dbSNP
rs1053810310 1522 dbSNP
rs1310899036 1523 dbSNP
rs893771779 1523 dbSNP
rs1036325636 1529 dbSNP
rs1204613156 1531 dbSNP
rs897827803 1534 dbSNP
rs1253044606 1535 dbSNP
rs535901283 1540 dbSNP
rs930918649 1541 dbSNP
rs1457798282 1545 dbSNP
rs1420681656 1547 dbSNP
rs1049306007 1548 dbSNP
rs1009830599 1553 dbSNP
rs1348313138 1555 dbSNP
rs80175350 1556 dbSNP
rs906783663 1561 dbSNP
rs569326584 1572 dbSNP
rs538414980 1573 dbSNP
rs1409958557 1574 dbSNP
rs894661397 1579 dbSNP
rs1003745075 1580 dbSNP
rs1170180903 1587 dbSNP
rs1033832291 1589 dbSNP
rs1469312994 1594 dbSNP
rs1377441311 1598 dbSNP
rs1176979375 1604 dbSNP
rs1481540620 1605 dbSNP
rs1249966319 1611 dbSNP
rs1181506971 1613 dbSNP
rs959133068 1621 dbSNP
rs1013064723 1627 dbSNP
rs571836372 1630 dbSNP
rs1252514266 1635 dbSNP
rs578190576 1643 dbSNP
rs1198670617 1645 dbSNP
rs984252674 1649 dbSNP
rs1256362726 1650 dbSNP
rs540975573 1654 dbSNP
rs554162584 1655 dbSNP
rs574091841 1658 dbSNP
rs1326612973 1683 dbSNP
rs1016612538 1684 dbSNP
rs1228431437 1687 dbSNP
rs1479390605 1690 dbSNP
rs906250113 1699 dbSNP
rs961298218 1700 dbSNP
rs1175575589 1709 dbSNP
rs972678766 1710 dbSNP
rs1401001016 1712 dbSNP
rs1402206419 1718 dbSNP
rs1467239570 1721 dbSNP
rs1471190447 1722 dbSNP
rs1409976679 1723 dbSNP
rs375427613 1724 dbSNP
rs1327012387 1727 dbSNP
rs1003242990 1738 dbSNP
rs767974795 1740 dbSNP
rs1185595166 1743 dbSNP
rs1441755831 1746 dbSNP
rs541890954 1751 dbSNP
rs1205294630 1755 dbSNP
rs1030657913 1756 dbSNP
rs576613427 1758 dbSNP
rs1011263945 1761 dbSNP
rs1352138319 1761 dbSNP
rs562977447 1768 dbSNP
rs1243508640 1769 dbSNP
rs1340376631 1774 dbSNP
rs766065686 1778 dbSNP
rs933897474 1778 dbSNP
rs985283652 1784 dbSNP
rs1320057536 1794 dbSNP
rs537780590 1795 dbSNP
rs911983748 1796 dbSNP
rs1161511006 1797 dbSNP
rs181458435 1798 dbSNP
rs1385745740 1800 dbSNP
rs1185372382 1806 dbSNP
rs1247188289 1807 dbSNP
rs1209200562 1818 dbSNP
rs1279364967 1818 dbSNP
rs1448361252 1820 dbSNP
rs1320701472 1822 dbSNP
rs1208698232 1825 dbSNP
rs1356460820 1826 dbSNP
rs1219863646 1827 dbSNP
rs1270289114 1828 dbSNP
rs1293063632 1828 dbSNP
rs1248804394 1833 dbSNP
rs1363725287 1834 dbSNP
rs1297303924 1837 dbSNP
rs1431993001 1838 dbSNP
rs1328391713 1851 dbSNP
rs972137315 1854 dbSNP
rs1404791220 1855 dbSNP
rs1366288784 1856 dbSNP
rs1165321397 1863 dbSNP
rs17883047 1866 dbSNP
rs1389547449 1869 dbSNP
rs930615038 1872 dbSNP
rs1221884965 1877 dbSNP
rs544017650 1883 dbSNP
rs1197738642 1887 dbSNP
rs1049799099 1894 dbSNP
rs1293310762 1897 dbSNP
rs893811670 1898 dbSNP
rs148074406 1911 dbSNP
rs948900143 1927 dbSNP
rs17879099 1929 dbSNP
rs766517434 1932 dbSNP
rs527533433 1946 dbSNP
rs1346463929 1949 dbSNP
rs1003275637 1953 dbSNP
rs1408135953 1959 dbSNP
rs1369845097 1960 dbSNP
rs1166176459 1966 dbSNP
rs547297077 1967 dbSNP
rs1171099556 1968 dbSNP
rs1418923087 1972 dbSNP
rs1422802818 1976 dbSNP
rs1171850161 1977 dbSNP
rs906810016 1978 dbSNP
rs1406129401 1982 dbSNP
rs1325742520 1983 dbSNP
rs1052115302 1984 dbSNP
rs1232758514 1989 dbSNP
rs1003777753 1990 dbSNP
rs1998322 1993 dbSNP
rs1276942685 2003 dbSNP
rs1299192267 2007 dbSNP
rs1219071921 2010 dbSNP
rs529665281 2014 dbSNP
rs1285476858 2015 dbSNP
rs1226611142 2016 dbSNP
rs758507623 2020 dbSNP
rs778936820 2023 dbSNP
rs1444284218 2032 dbSNP
rs1357412912 2033 dbSNP
rs1005308090 2037 dbSNP
rs1017055865 2044 dbSNP
rs186404729 2047 dbSNP
rs1430920779 2053 dbSNP
rs35709381 2055 dbSNP
rs116644674 2060 dbSNP
rs551948955 2064 dbSNP
rs190748872 2066 dbSNP
rs1471434904 2068 dbSNP
rs141848466 2069 dbSNP
rs911064017 2070 dbSNP
rs1207060182 2077 dbSNP
rs554526554 2084 dbSNP
rs957395656 2087 dbSNP
rs989999232 2089 dbSNP
rs915347500 2091 dbSNP
rs1307778061 2099 dbSNP
rs1356915824 2106 dbSNP
rs781007275 2113 dbSNP
rs1376844854 2118 dbSNP
rs1283556731 2119 dbSNP
rs1042433528 2120 dbSNP
rs927925403 2121 dbSNP
rs1456374528 2144 dbSNP
rs1345480585 2149 dbSNP
rs1421589448 2150 dbSNP
rs745612717 2151 dbSNP
rs939594940 2155 dbSNP
rs76354453 2157 dbSNP
rs915892315 2161 dbSNP
rs1245347005 2165 dbSNP
rs1190975574 2179 dbSNP
rs895318570 2189 dbSNP
rs536631177 2190 dbSNP
rs1320023666 2201 dbSNP
rs1473155736 2202 dbSNP
rs949029936 2209 dbSNP
rs556321658 2217 dbSNP
rs1330479929 2218 dbSNP
rs1384989253 2219 dbSNP
rs1295114285 2228 dbSNP
rs1165133645 2236 dbSNP
rs1434159647 2242 dbSNP
rs1362189073 2244 dbSNP
rs1290300702 2245 dbSNP
rs1383547697 2264 dbSNP
rs1348813064 2265 dbSNP
rs1046390615 2266 dbSNP
rs757336043 2271 dbSNP
rs928830462 2271 dbSNP
rs779804598 2273 dbSNP
rs576476847 2274 dbSNP
rs1188519114 2275 dbSNP
rs536463089 2278 dbSNP
rs1352205093 2286 dbSNP
rs545172205 2288 dbSNP
rs1318219900 2294 dbSNP
rs1226372182 2295 dbSNP
rs1038529053 2296 dbSNP
rs1297207829 2304 dbSNP
rs1384708036 2305 dbSNP
rs113331160 2331 dbSNP
rs1303203503 2333 dbSNP
rs1010991958 2335 dbSNP
rs896921831 2336 dbSNP
rs565048356 2339 dbSNP
rs1167286427 2340 dbSNP
rs993908213 2350 dbSNP
rs1173071316 2352 dbSNP
rs1029298501 2353 dbSNP
rs1428919385 2369 dbSNP
rs1043439581 2378 dbSNP
rs888772371 2385 dbSNP
rs748925894 2392 dbSNP
rs1195176268 2394 dbSNP
rs768464118 2406 dbSNP
rs1480800283 2415 dbSNP
rs1006766471 2420 dbSNP
rs1252837200 2422 dbSNP
rs1018188786 2425 dbSNP
rs1322360523 2426 dbSNP
rs1283558182 2433 dbSNP
rs114270396 2439 dbSNP
rs1244823057 2440 dbSNP
rs1286418231 2441 dbSNP
rs990415722 2448 dbSNP
rs1391317167 2449 dbSNP
rs773905994 2449 dbSNP
rs967213156 2450 dbSNP
rs772569708 2451 dbSNP
rs1442937318 2453 dbSNP
rs111625800 2454 dbSNP
rs1405574541 2456 dbSNP
rs1177453501 2466 dbSNP
rs1409859524 2468 dbSNP
rs927958025 2468 dbSNP
rs1181249105 2474 dbSNP
rs1419573862 2475 dbSNP
rs1252626965 2480 dbSNP
rs985271608 2485 dbSNP
rs1444193212 2487 dbSNP
rs1263312877 2493 dbSNP
rs939293853 2496 dbSNP
rs1326718595 2503 dbSNP
rs1382447714 2506 dbSNP
rs111400098 2509 dbSNP
rs560829333 2510 dbSNP
rs1336840912 2512 dbSNP
rs1309824990 2515 dbSNP
rs1403452775 2517 dbSNP
rs941604167 2521 dbSNP
rs934837192 2522 dbSNP
rs1338075470 2525 dbSNP
rs1379985847 2532 dbSNP
rs761056691 2535 dbSNP
rs1471078302 2536 dbSNP
rs1383131997 2539 dbSNP
rs1451332657 2541 dbSNP
rs897293993 2549 dbSNP
rs1309501342 2552 dbSNP
rs993887465 2557 dbSNP
rs914722582 2567 dbSNP
rs1443710535 2569 dbSNP
rs1243522383 2571 dbSNP
rs1050764627 2572 dbSNP
rs1337225205 2585 dbSNP
rs1236608241 2587 dbSNP
rs1278751676 2589 dbSNP
rs946521504 2599 dbSNP
rs1043854080 2604 dbSNP
rs180948009 2606 dbSNP
rs561324575 2614 dbSNP
rs1205165360 2615 dbSNP
rs1352247992 2616 dbSNP
rs1262956007 2619 dbSNP
rs1244432520 2620 dbSNP
rs888812655 2625 dbSNP
rs890874961 2629 dbSNP
rs1316137926 2632 dbSNP
rs943008271 2634 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agugguaacGAUUUCACGUUAa 5'
                   | | :||||:|| 
Target 5' ---------CAAUGGUGCGAUc 3'
 		1 - 13
2 
miRNA  3' agugguaacgauuucACGUUAA------ 5'
                         ||||||       
Target 5' gcgaucucggcucacUGCAAUCUCCACC 3'
 		8 - 35
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000371321.3 | 3UTR | CAAUGGUGCGAUCUCGGCUCACUGCAAUCUCCACCUCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.51 5.4e-3 0.532 3.7e-3 24 Click to see details
GSE32688 Pancreatic cancer -0.269 6.8e-2 -0.417 8.8e-3 32 Click to see details
GSE28260 Renal cortex and medulla -0.361 1.1e-1 -0.551 2.5e-2 13 Click to see details
GSE19350 CNS germ cell tumors 0.333 1.5e-1 0.203 2.6e-1 12 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.151 2.4e-1 0.306 6.8e-2 25 Click to see details
GSE27834 Pluripotent stem cells -0.176 2.6e-1 -0.385 7.0e-2 16 Click to see details
GSE21687 Ependynoma primary tumors 0.07 2.9e-1 0.039 3.8e-1 64 Click to see details
GSE38226 Liver fibrosis 0.099 3.3e-1 0.175 2.2e-1 21 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.141 4.1e-1 0.200 3.7e-1 5 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.054 4.1e-1 -0.266 1.3e-1 20 Click to see details
GSE14794 Lymphoblastoid cells 0.021 4.2e-1 -0.006 4.8e-1 90 Click to see details
GSE21849 B cell lymphoma -0.03 4.4e-1 0.349 3.2e-2 29 Click to see details
GSE17306 Multiple myeloma -0.013 4.6e-1 0.471 3.2e-4 49 Click to see details
GSE17498 Multiple myeloma -0.012 4.7e-1 -0.008 4.8e-1 40 Click to see details
GSE26953 Aortic valvular endothelial cells -0.005 4.9e-1 -0.002 5.0e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells -0.005 4.9e-1 -0.002 5.0e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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