miRTarBase - #MIRT456163


—
pre-miRNA Information
pre-miRNA hsa-mir-4270   
Genomic Coordinates chr3: 15496239 - 15496308
Description Homo sapiens miR-4270 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4270
Sequence 11| UCAGGGAGUCAGGGGAGGGC |30
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs991570490 2 dbSNP
rs1417709982 10 dbSNP
rs960511282 12 dbSNP
rs928808979 14 dbSNP
rs1372156971 15 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TTF2   
Synonyms HuF2, ZGRF6
Description transcription termination factor 2
Transcript NM_003594   
Expression
Putative miRNA Targets on TTF2
3'UTR of TTF2
(miRNA target sites are highlighted)		 
>TTF2|NM_003594|3'UTR
   1 CCTCCTGTGGATAAGGGCTCAGAATAGCACCATTGCTGGTTTGTATTAGGATCTGGGAATAACAACCTAACCATGAGCCT
  81 TGAACTCTGTTCTTTGCATTTCAATTTCACCGTCAAGCCTTTCACCTTCCTCAAAATGAGGCATAATCTTATCCCCAGAA
 161 TTGAGGAGGGGTTGTGTTAACCAATTAGTTAACCAATTATGTTAATAATTTATTTAATGAGTGGTATGGAAACCAATTGA
 241 TTTTTTTAGATAAAAGAATATGTTTTAGAGTTGGATGATTTTGGAAAACAACTCTGGCAGAATTGTATATAAGCTTCAGT
 321 AAAGTTCAAAAAGCGGGCCAGGTGTGGTGGCTCATGCCTGTAATCCCGACACTTTGGGAGGCCAAGGCAGGAGGATGGCT
 401 TGAAGCCAGTAGTTCAAGACCAGCCTGGGCAACATAGTAAGACCCCATCTCTATGAAGAATAAAAAAATGAGCTAGGCGT
 481 GGTAGTGCACACCTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGGATCCCTTGAGTCCAGGAGGTTGAGGCTGCAG
 561 TGAGCTGTGATTGTGCCACTGTTTTCCAGCCTGGGCAATACAGTGAGACCCTGTCTCAAAAAAAGGAAAAAAAAGCTCAA
 641 AAAGTTCTGTGTTGCCTTTCTCTTCTTAGCTGATGATGGGAGAACCAGTTACTACCTTCTCTAACACAGGCTCCATCCTA
 721 TCTCTTCATCTCTTCTTGCCAGTGATGTTGCACCTGTAACCATCTTTTTATGGGTGGAGCAGAGAGTCAATCCCTGCAGC
 801 CACCCTGCAGCCAGCCATCTCTGCAGTTCTCTCAGTGCAGGCAGTTCTTCCTCTCAGGCTGAAGATCAAGGAGATGCTTT
 881 GTACATGAACAGATGCTGAGTATCTGTTATCATTGTATTGTTTAGTGTCAGTGTATCATTTAGTATTTGTATCACTGTAC
 961 CATTTAGTGTTGTATATCACTCAGTCATTTAATATTGGTTATCACCATACAGTTTAATATTTGTATCATTTGGTTCATTG
1041 TATCGTTTAGTATTTCTATTATAACATTTCTATTTGTAGTATTTGTATAATATTTGTGTCATTTTTAATAGTATTTGTAT
1121 TTTTACAAATTTGCAGTATTTGTAGCATTTAGTATCATTGTTTCATTTAGTATTTGGTACAATCTAATAAATACTAATCC
1201 AGTCCAATACTAATCCAATCCAATACTAATAATACTATTGGTACAATCCAATACTAATAATACTATTGGTACAATCCAAT
1281 ACTAATAATACTAACAGTAGTATTGATACAATCTAATAAATAATGTGTTTGACAGTGTAGCAGAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgGGAGGGG-ACUGAGGGACu 5'
            :|||::| |  ||:|:|| 
Target 5' taTCTCTTCATCTCTTCTTGc 3'
 719 - 739 122.00 -14.40
2 
miRNA  3' cgggAGGG--GACUGAGGGACu 5'
              ||||  | | | ||||| 
Target 5' tcaaTCCCTGCAGCCACCCTGc 3'
 787 - 808 122.00 -17.60
3 
miRNA  3' cgggaGGGGACU-GAGGGAcu 5'
               ||::| | ||:|||  
Target 5' tcaagCCTTTCACCTTCCTca 3'
 113 - 133 115.00 -15.82
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30486286 34 COSMIC
COSN31600305 91 COSMIC
COSN30479494 112 COSMIC
COSN30523630 119 COSMIC
COSN30449271 137 COSMIC
COSN28198345 803 COSMIC
COSN20095244 804 COSMIC
COSN8888687 1224 COSMIC
COSN6504372 1599 COSMIC
COSN22262383 1878 COSMIC
COSN21136772 2296 COSMIC
COSN8888688 2448 COSMIC
COSN30595951 3293 COSMIC
COSN20761863 3783 COSMIC
COSN23713315 3844 COSMIC
COSN29718038 4270 COSMIC
COSN17825223 4271 COSMIC
COSN9361500 4618 COSMIC
COSN27433796 4763 COSMIC
COSN1087728 4783 COSMIC
COSN8888689 5705 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs539233928 1 dbSNP
rs746937712 2 dbSNP
rs757093550 4 dbSNP
rs71668685 5 dbSNP
rs1448423385 10 dbSNP
rs1166179240 11 dbSNP
rs377536966 14 dbSNP
rs1227237002 21 dbSNP
rs1376564999 22 dbSNP
rs1271547828 29 dbSNP
rs745600241 30 dbSNP
rs1163762536 31 dbSNP
rs1347946661 32 dbSNP
rs370970458 33 dbSNP
rs866472921 39 dbSNP
rs768342013 40 dbSNP
rs779504441 40 dbSNP
rs1326570201 45 dbSNP
rs375192978 46 dbSNP
rs183707184 52 dbSNP
rs1463422655 53 dbSNP
rs527525704 54 dbSNP
rs370204804 61 dbSNP
rs1032318253 69 dbSNP
rs937452060 71 dbSNP
rs1323898553 74 dbSNP
rs1421981637 75 dbSNP
rs536365682 88 dbSNP
rs1350689604 92 dbSNP
rs1435971648 93 dbSNP
rs895837510 102 dbSNP
rs17036853 105 dbSNP
rs1469818303 112 dbSNP
rs138133230 113 dbSNP
rs1342426591 125 dbSNP
rs1041690705 126 dbSNP
rs776589909 139 dbSNP
rs1274712242 143 dbSNP
rs1000697780 145 dbSNP
rs11545909 147 dbSNP
rs1214723100 154 dbSNP
rs1032142107 165 dbSNP
rs544446177 168 dbSNP
rs1295941110 173 dbSNP
rs1316503804 175 dbSNP
rs995956804 185 dbSNP
rs1061441 189 dbSNP
rs562437942 196 dbSNP
rs981353947 213 dbSNP
rs768576270 216 dbSNP
rs954472970 225 dbSNP
rs1290989468 227 dbSNP
rs1004585517 240 dbSNP
rs1356317081 241 dbSNP
rs963642121 248 dbSNP
rs765232168 260 dbSNP
rs973703809 261 dbSNP
rs1014596188 280 dbSNP
rs1388543270 283 dbSNP
rs919577517 287 dbSNP
rs1264757602 292 dbSNP
rs577556489 302 dbSNP
rs963626271 307 dbSNP
rs973619112 328 dbSNP
rs750728556 335 dbSNP
rs149572278 336 dbSNP
rs1487220709 338 dbSNP
rs143246974 339 dbSNP
rs992995546 341 dbSNP
rs917352373 348 dbSNP
rs943849186 359 dbSNP
rs1163653736 366 dbSNP
rs186542737 368 dbSNP
rs946131362 369 dbSNP
rs1041700642 373 dbSNP
rs746643214 373 dbSNP
rs1039532741 389 dbSNP
rs1375639960 396 dbSNP
rs1298883547 403 dbSNP
rs925920430 404 dbSNP
rs1162907436 406 dbSNP
rs1368997591 413 dbSNP
rs1175704999 414 dbSNP
rs1362609520 422 dbSNP
rs1400675436 431 dbSNP
rs1297590921 436 dbSNP
rs1431427059 437 dbSNP
rs1252574151 439 dbSNP
rs936604125 440 dbSNP
rs1482430776 441 dbSNP
rs1249196063 446 dbSNP
rs1053606229 448 dbSNP
rs1339136983 448 dbSNP
rs41276574 454 dbSNP
rs1483788428 462 dbSNP
rs936579769 462 dbSNP
rs996441649 463 dbSNP
rs1053654835 469 dbSNP
rs1308308297 472 dbSNP
rs1226329743 473 dbSNP
rs41276576 479 dbSNP
rs1348664795 480 dbSNP
rs1010015474 481 dbSNP
rs890242798 485 dbSNP
rs1353907512 490 dbSNP
rs1401751634 491 dbSNP
rs1215261427 492 dbSNP
rs1260352497 493 dbSNP
rs569437934 497 dbSNP
rs1014607562 498 dbSNP
rs1365516291 499 dbSNP
rs1444081212 512 dbSNP
rs182828723 520 dbSNP
rs995108312 524 dbSNP
rs879075906 528 dbSNP
rs550949854 536 dbSNP
rs1424093986 544 dbSNP
rs963566087 545 dbSNP
rs569286552 552 dbSNP
rs536538315 574 dbSNP
rs1487024364 576 dbSNP
rs1269352606 577 dbSNP
rs1161963652 578 dbSNP
rs1035039998 592 dbSNP
rs1208575888 593 dbSNP
rs1382414482 604 dbSNP
rs1327178277 608 dbSNP
rs958975848 610 dbSNP
rs1233975354 612 dbSNP
rs1310824288 616 dbSNP
rs549797487 617 dbSNP
rs995067609 618 dbSNP
rs1420498093 619 dbSNP
rs917382689 621 dbSNP
rs1026605184 627 dbSNP
rs1456590484 627 dbSNP
rs1166513451 630 dbSNP
rs951047758 632 dbSNP
rs571963251 637 dbSNP
rs1184905220 639 dbSNP
rs773194171 641 dbSNP
rs1340311012 643 dbSNP
rs1188312789 652 dbSNP
rs977445945 661 dbSNP
rs1446301764 670 dbSNP
rs925972875 673 dbSNP
rs936025751 677 dbSNP
rs1275565726 686 dbSNP
rs1410747059 697 dbSNP
rs1263934837 703 dbSNP
rs1229806471 704 dbSNP
rs1367114064 712 dbSNP
rs1298145912 721 dbSNP
rs912292770 726 dbSNP
rs1039694105 728 dbSNP
rs1363000802 731 dbSNP
rs965517113 740 dbSNP
rs752152281 743 dbSNP
rs1405474636 746 dbSNP
rs1389299424 756 dbSNP
rs1161107994 757 dbSNP
rs931915896 763 dbSNP
rs532893273 768 dbSNP
rs890261845 771 dbSNP
rs975162005 782 dbSNP
rs1004649200 791 dbSNP
rs1010302284 791 dbSNP
rs1386664589 792 dbSNP
rs398053383 792 dbSNP
rs60599950 792 dbSNP
rs1036091896 793 dbSNP
rs913815162 796 dbSNP
rs1201032740 802 dbSNP
rs945356961 803 dbSNP
rs115314774 804 dbSNP
rs1046849212 811 dbSNP
rs898898723 835 dbSNP
rs994536262 840 dbSNP
rs1343228672 842 dbSNP
rs372089019 852 dbSNP
rs1227415832 854 dbSNP
rs894719197 856 dbSNP
rs1440568611 864 dbSNP
rs1276547842 872 dbSNP
rs1180280813 874 dbSNP
rs1437034341 874 dbSNP
rs1330435817 877 dbSNP
rs566289298 880 dbSNP
rs1024905044 895 dbSNP
rs899327861 899 dbSNP
rs1306972580 902 dbSNP
rs1428258591 904 dbSNP
rs1397202438 909 dbSNP
rs555291268 914 dbSNP
rs1478022918 930 dbSNP
rs1376430384 932 dbSNP
rs1026530022 933 dbSNP
rs977539276 934 dbSNP
rs1251396479 951 dbSNP
rs1203200911 961 dbSNP
rs1481956505 963 dbSNP
rs1033085007 978 dbSNP
rs1019687782 982 dbSNP
rs748981702 983 dbSNP
rs865823803 987 dbSNP
rs1272978975 996 dbSNP
rs1229721897 999 dbSNP
rs965096558 1003 dbSNP
rs957443947 1018 dbSNP
rs1173178028 1032 dbSNP
rs1407555389 1033 dbSNP
rs1360527228 1039 dbSNP
rs975858541 1040 dbSNP
rs975130584 1045 dbSNP
rs770533255 1046 dbSNP
rs1160753221 1050 dbSNP
rs780421619 1051 dbSNP
rs1411254949 1061 dbSNP
rs1333813362 1064 dbSNP
rs1180087565 1079 dbSNP
rs1476347283 1086 dbSNP
rs536707944 1086 dbSNP
rs1401450624 1087 dbSNP
rs987378111 1090 dbSNP
rs1238238005 1091 dbSNP
rs1445629781 1100 dbSNP
rs1441584308 1110 dbSNP
rs957832243 1110 dbSNP
rs989275041 1111 dbSNP
rs1210442716 1113 dbSNP
rs1306623398 1118 dbSNP
rs911747491 1123 dbSNP
rs539853685 1124 dbSNP
rs913794567 1129 dbSNP
rs1226038062 1133 dbSNP
rs1332374836 1134 dbSNP
rs1353103894 1135 dbSNP
rs1284405721 1139 dbSNP
rs1447795750 1141 dbSNP
rs945299984 1155 dbSNP
rs1323151161 1157 dbSNP
rs1458279636 1158 dbSNP
rs1046336539 1162 dbSNP
rs927934364 1165 dbSNP
rs938031044 1169 dbSNP
rs1342813551 1175 dbSNP
rs1055205884 1188 dbSNP
rs1472346934 1190 dbSNP
rs1235465821 1193 dbSNP
rs1190258939 1194 dbSNP
rs940530441 1205 dbSNP
rs930776897 1209 dbSNP
rs1206341612 1211 dbSNP
rs1290149590 1216 dbSNP
rs1258515319 1217 dbSNP
rs1227325105 1227 dbSNP
rs554767558 1232 dbSNP
rs1198319429 1233 dbSNP
rs1300346153 1237 dbSNP
rs1048377047 1238 dbSNP
rs1365165847 1242 dbSNP
rs747342863 1261 dbSNP
rs147499220 1266 dbSNP
rs1350476101 1271 dbSNP
rs537040143 1277 dbSNP
rs1164365264 1278 dbSNP
rs558562749 1282 dbSNP
rs1199717880 1283 dbSNP
rs1170301753 1284 dbSNP
rs1449826614 1284 dbSNP
rs1377088169 1299 dbSNP
rs1055873694 1306 dbSNP
rs1186519001 1310 dbSNP
rs1489181356 1326 dbSNP
rs1009544745 1328 dbSNP
rs188201749 1343 dbSNP
rs1319592710 1344 dbSNP
rs900827505 1354 dbSNP
rs996477423 1355 dbSNP
rs76402823 1357 dbSNP
rs1027989476 1365 dbSNP
rs35358158 1365 dbSNP
rs1341848321 1373 dbSNP
rs1296053003 1375 dbSNP
rs777265775 1386 dbSNP
rs1024582705 1387 dbSNP
rs903431684 1388 dbSNP
rs1465420423 1396 dbSNP
rs1434362452 1399 dbSNP
rs989243932 1400 dbSNP
rs1430167632 1409 dbSNP
rs1389252751 1412 dbSNP
rs762208383 1433 dbSNP
rs375084815 1434 dbSNP
rs74498574 1437 dbSNP
rs553517608 1441 dbSNP
rs957454016 1447 dbSNP
rs572156671 1448 dbSNP
rs927934857 1449 dbSNP
rs1205345024 1450 dbSNP
rs1482941693 1452 dbSNP
rs1278753579 1454 dbSNP
rs1235883386 1457 dbSNP
rs1317165721 1465 dbSNP
rs1301165309 1468 dbSNP
rs1216578000 1472 dbSNP
rs1217571567 1473 dbSNP
rs1289229006 1473 dbSNP
rs773391935 1477 dbSNP
rs1409501550 1479 dbSNP
rs1489599442 1480 dbSNP
rs937959096 1482 dbSNP
rs990839036 1483 dbSNP
rs920650627 1485 dbSNP
rs3965 1489 dbSNP
rs566497448 1490 dbSNP
rs1266808629 1491 dbSNP
rs1489878124 1494 dbSNP
rs1479188454 1505 dbSNP
rs987189441 1511 dbSNP
rs1196542037 1514 dbSNP
rs1182239835 1520 dbSNP
rs560819731 1521 dbSNP
rs1472082334 1522 dbSNP
rs1264546605 1526 dbSNP
rs1202609057 1529 dbSNP
rs911842400 1532 dbSNP
rs1255921276 1534 dbSNP
rs940582754 1542 dbSNP
rs1202281966 1547 dbSNP
rs1331816433 1550 dbSNP
rs1268896101 1551 dbSNP
rs971932989 1561 dbSNP
rs1348928231 1563 dbSNP
rs531477149 1566 dbSNP
rs944928122 1568 dbSNP
rs1397569197 1569 dbSNP
rs1040994960 1576 dbSNP
rs900764160 1577 dbSNP
rs34208395 1579 dbSNP
rs996443248 1579 dbSNP
rs9728670 1599 dbSNP
rs1370543233 1608 dbSNP
rs1159341963 1612 dbSNP
rs140128409 1624 dbSNP
rs1055524563 1628 dbSNP
rs532817205 1630 dbSNP
rs558740262 1631 dbSNP
rs1424786402 1632 dbSNP
rs191393378 1636 dbSNP
rs141201437 1645 dbSNP
rs866025438 1647 dbSNP
rs1466693711 1648 dbSNP
rs759307817 1649 dbSNP
rs530227688 1650 dbSNP
rs767211934 1663 dbSNP
rs1267489018 1665 dbSNP
rs1298204277 1674 dbSNP
rs1339799710 1679 dbSNP
rs1311792033 1684 dbSNP
rs1398021345 1693 dbSNP
rs903483686 1697 dbSNP
rs752729291 1700 dbSNP
rs1054560671 1701 dbSNP
rs1433713873 1702 dbSNP
rs1382086996 1730 dbSNP
rs1164475437 1732 dbSNP
rs1458135405 1742 dbSNP
rs1162130043 1743 dbSNP
rs990766861 1743 dbSNP
rs1245885033 1753 dbSNP
rs893276862 1756 dbSNP
rs543903849 1758 dbSNP
rs555697053 1759 dbSNP
rs753298059 1765 dbSNP
rs373572812 1770 dbSNP
rs9730051 1770 dbSNP
rs1008264746 1772 dbSNP
rs1218893192 1775 dbSNP
rs537579603 1780 dbSNP
rs114521470 1781 dbSNP
rs1210475444 1793 dbSNP
rs79446494 1801 dbSNP
rs1289842818 1807 dbSNP
rs868042238 1809 dbSNP
rs971944249 1812 dbSNP
rs1040564996 1813 dbSNP
rs1343953075 1821 dbSNP
rs1258781311 1846 dbSNP
rs920442794 1849 dbSNP
rs1226537566 1854 dbSNP
rs951935585 1870 dbSNP
rs1324591501 1880 dbSNP
rs1424748520 1882 dbSNP
rs1325032296 1883 dbSNP
rs1187215478 1886 dbSNP
rs1386835557 1893 dbSNP
rs1383010814 1894 dbSNP
rs1421103099 1897 dbSNP
rs753398077 1906 dbSNP
rs1359322585 1907 dbSNP
rs879650577 1918 dbSNP
rs922158701 1925 dbSNP
rs1391119283 1933 dbSNP
rs991717507 1956 dbSNP
rs1379875142 1966 dbSNP
rs1474736037 1966 dbSNP
rs1304506685 1968 dbSNP
rs1054658642 1969 dbSNP
rs893468588 1986 dbSNP
rs745506231 1992 dbSNP
rs1218917555 1993 dbSNP
rs1395251745 1994 dbSNP
rs139139933 2004 dbSNP
rs769127037 2008 dbSNP
rs1242520759 2019 dbSNP
rs1337437416 2033 dbSNP
rs1286881628 2046 dbSNP
rs1233348554 2051 dbSNP
rs781384512 2055 dbSNP
rs1281002255 2057 dbSNP
rs1411331277 2064 dbSNP
rs924246333 2065 dbSNP
rs1370755196 2067 dbSNP
rs1307880877 2068 dbSNP
rs541754536 2075 dbSNP
rs1404999132 2083 dbSNP
rs1003759385 2086 dbSNP
rs1054613621 2088 dbSNP
rs770381743 2089 dbSNP
rs1184406846 2095 dbSNP
rs959216465 2110 dbSNP
rs997055553 2114 dbSNP
rs1050343176 2129 dbSNP
rs115384957 2137 dbSNP
rs1008279166 2138 dbSNP
rs35330167 2141 dbSNP
rs1015614009 2148 dbSNP
rs1229691425 2152 dbSNP
rs58973682 2153 dbSNP
rs182198131 2154 dbSNP
rs1178828979 2164 dbSNP
rs1027600956 2165 dbSNP
rs952046505 2174 dbSNP
rs771281186 2176 dbSNP
rs1161541923 2185 dbSNP
rs1177529226 2194 dbSNP
rs187919551 2197 dbSNP
rs774701075 2198 dbSNP
rs1334471818 2206 dbSNP
rs932191582 2207 dbSNP
rs139020209 2213 dbSNP
rs971205564 2214 dbSNP
rs981142950 2222 dbSNP
rs79355779 2226 dbSNP
rs1372804030 2236 dbSNP
rs1222147540 2239 dbSNP
rs1303451392 2240 dbSNP
rs1329158147 2246 dbSNP
rs1313324262 2251 dbSNP
rs1203568248 2252 dbSNP
rs924303509 2256 dbSNP
rs1261701719 2257 dbSNP
rs934345326 2258 dbSNP
rs1054020264 2259 dbSNP
rs1237197910 2266 dbSNP
rs1381247612 2278 dbSNP
rs1479414784 2279 dbSNP
rs1435950183 2282 dbSNP
rs759655656 2282 dbSNP
rs1192458523 2286 dbSNP
rs932855364 2290 dbSNP
rs1049962335 2291 dbSNP
rs891278220 2294 dbSNP
rs944129567 2298 dbSNP
rs200230434 2299 dbSNP
rs1037138785 2302 dbSNP
rs543554487 2303 dbSNP
rs1041165266 2304 dbSNP
rs1212992660 2305 dbSNP
rs767386943 2309 dbSNP
rs1290079171 2311 dbSNP
rs564825326 2324 dbSNP
rs1357695852 2325 dbSNP
rs1300476922 2328 dbSNP
rs760686741 2336 dbSNP
rs576907927 2338 dbSNP
rs1003277700 2344 dbSNP
rs887740625 2345 dbSNP
rs1013241988 2360 dbSNP
rs1440235234 2374 dbSNP
rs1302708813 2376 dbSNP
rs1022826690 2382 dbSNP
rs971185739 2384 dbSNP
rs981216479 2385 dbSNP
rs867084893 2386 dbSNP
rs1478689045 2387 dbSNP
rs955754091 2390 dbSNP
rs1489708397 2414 dbSNP
rs1281911153 2415 dbSNP
rs541073604 2416 dbSNP
rs1219637685 2417 dbSNP
rs1293985484 2421 dbSNP
rs1272690939 2423 dbSNP
rs1305426117 2424 dbSNP
rs1491314007 2427 dbSNP
rs1198031409 2428 dbSNP
rs1353868639 2428 dbSNP
rs1357968002 2428 dbSNP
rs1415708304 2428 dbSNP
rs1429441234 2428 dbSNP
rs1479290489 2428 dbSNP
rs532560004 2428 dbSNP
rs778355624 2428 dbSNP
rs894975423 2428 dbSNP
rs76488139 2429 dbSNP
rs75122774 2433 dbSNP
rs1178151835 2437 dbSNP
rs1012096484 2443 dbSNP
rs1223283184 2445 dbSNP
rs1250157811 2445 dbSNP
rs1212795299 2446 dbSNP
rs1347530168 2446 dbSNP
rs1027535616 2447 dbSNP
rs1246824587 2447 dbSNP
rs1352620065 2448 dbSNP
rs1372284465 2448 dbSNP
rs1391793589 2448 dbSNP
rs989775508 2448 dbSNP
rs1296220439 2449 dbSNP
rs1450177487 2450 dbSNP
rs914217446 2452 dbSNP
rs1406727526 2454 dbSNP
rs1005261681 2456 dbSNP
rs932949232 2456 dbSNP
rs1014911478 2458 dbSNP
rs986100284 2463 dbSNP
rs1418884412 2464 dbSNP
rs966462498 2465 dbSNP
rs1196577324 2466 dbSNP
rs1462203789 2475 dbSNP
rs976132318 2478 dbSNP
rs922053782 2479 dbSNP
rs1261556315 2480 dbSNP
rs953512690 2482 dbSNP
rs1265252962 2483 dbSNP
rs1315320102 2496 dbSNP
rs1304686470 2517 dbSNP
rs912792991 2520 dbSNP
rs944202040 2524 dbSNP
rs1383457977 2530 dbSNP
rs1037169848 2534 dbSNP
rs1449870221 2540 dbSNP
rs1390140937 2543 dbSNP
rs1288919913 2564 dbSNP
rs946308461 2570 dbSNP
rs897247911 2580 dbSNP
rs931383826 2590 dbSNP
rs978101810 2591 dbSNP
rs923628179 2592 dbSNP
rs1445552453 2610 dbSNP
rs559785464 2617 dbSNP
rs1169726982 2624 dbSNP
rs1182235941 2628 dbSNP
rs545993463 2646 dbSNP
rs939049235 2652 dbSNP
rs1262569806 2657 dbSNP
rs530457848 2662 dbSNP
rs1204628097 2666 dbSNP
rs895124881 2670 dbSNP
rs1267396999 2673 dbSNP
rs1012858860 2683 dbSNP
rs1247907590 2687 dbSNP
rs1023322033 2690 dbSNP
rs1167165882 2691 dbSNP
rs907099819 2698 dbSNP
rs1314319994 2705 dbSNP
rs548473397 2719 dbSNP
rs1243747359 2722 dbSNP
rs1056194847 2725 dbSNP
rs192340546 2735 dbSNP
rs1295749716 2742 dbSNP
rs1381144790 2746 dbSNP
rs530874492 2751 dbSNP
rs1294850183 2754 dbSNP
rs947847407 2760 dbSNP
rs552263677 2770 dbSNP
rs1365401281 2775 dbSNP
rs1162026571 2778 dbSNP
rs1048940236 2779 dbSNP
rs1301296953 2789 dbSNP
rs1192582781 2794 dbSNP
rs1031426279 2795 dbSNP
rs1426743769 2796 dbSNP
rs149868996 2798 dbSNP
rs1401089455 2801 dbSNP
rs990295180 2801 dbSNP
rs756831695 2811 dbSNP
rs564278169 2827 dbSNP
rs1004782567 2832 dbSNP
rs1341453466 2858 dbSNP
rs1251757282 2864 dbSNP
rs1226060713 2867 dbSNP
rs1284623724 2885 dbSNP
rs953864286 2896 dbSNP
rs1344475243 2899 dbSNP
rs1255966384 2902 dbSNP
rs1290167807 2905 dbSNP
rs146429010 2913 dbSNP
rs1431952328 2920 dbSNP
rs901835905 2924 dbSNP
rs997480257 2926 dbSNP
rs1219661233 2935 dbSNP
rs1379494852 2946 dbSNP
rs1028994170 2949 dbSNP
rs1480270571 2969 dbSNP
rs1287483453 2971 dbSNP
rs368605279 2975 dbSNP
rs953480602 2977 dbSNP
rs990224139 2980 dbSNP
rs1192348192 2989 dbSNP
rs1195213099 2991 dbSNP
rs139945395 2997 dbSNP
rs757953058 3002 dbSNP
rs972936333 3003 dbSNP
rs115853051 3005 dbSNP
rs1322419380 3006 dbSNP
rs1196206485 3010 dbSNP
rs928891465 3015 dbSNP
rs1336674421 3017 dbSNP
rs1328575033 3046 dbSNP
rs1424211870 3048 dbSNP
rs748414424 3050 dbSNP
rs1048938966 3066 dbSNP
rs1177311316 3085 dbSNP
rs1469299621 3099 dbSNP
rs1427464915 3103 dbSNP
rs1362514531 3104 dbSNP
rs938961911 3110 dbSNP
rs551135950 3115 dbSNP
rs554430753 3127 dbSNP
rs916306342 3133 dbSNP
rs1318242118 3136 dbSNP
rs189886157 3153 dbSNP
rs753567445 3154 dbSNP
rs1046356797 3157 dbSNP
rs778359699 3175 dbSNP
rs749808870 3179 dbSNP
rs947770579 3190 dbSNP
rs1381616503 3192 dbSNP
rs1243296171 3193 dbSNP
rs1260893132 3194 dbSNP
rs1310870899 3195 dbSNP
rs1350902141 3197 dbSNP
rs537105712 3207 dbSNP
rs558679113 3208 dbSNP
rs577061032 3212 dbSNP
rs1279407075 3213 dbSNP
rs1237318194 3214 dbSNP
rs1002741886 3216 dbSNP
rs1052915460 3221 dbSNP
rs891615506 3230 dbSNP
rs192948661 3231 dbSNP
rs559335474 3236 dbSNP
rs1021808392 3237 dbSNP
rs1401574699 3240 dbSNP
rs1407518567 3253 dbSNP
rs1157800607 3263 dbSNP
rs953789281 3264 dbSNP
rs574998762 3271 dbSNP
rs887613169 3274 dbSNP
rs940551860 3275 dbSNP
rs1460799099 3279 dbSNP
rs1006971985 3280 dbSNP
rs771193157 3281 dbSNP
rs112737160 3285 dbSNP
rs1217304913 3285 dbSNP
rs146722231 3286 dbSNP
rs1242251807 3288 dbSNP
rs1361983878 3299 dbSNP
rs1444288587 3305 dbSNP
rs1181944647 3319 dbSNP
rs184925781 3336 dbSNP
rs1272065349 3344 dbSNP
rs1431503607 3354 dbSNP
rs1344836928 3359 dbSNP
rs889140298 3361 dbSNP
rs1011614694 3365 dbSNP
rs1417657650 3369 dbSNP
rs953010947 3370 dbSNP
rs1383478560 3378 dbSNP
rs984276260 3381 dbSNP
rs967538233 3389 dbSNP
rs916659375 3402 dbSNP
rs948123194 3403 dbSNP
rs552392699 3416 dbSNP
rs1475415765 3421 dbSNP
rs564235945 3422 dbSNP
rs1241186778 3432 dbSNP
rs1190510942 3438 dbSNP
rs1490731234 3439 dbSNP
rs775367704 3446 dbSNP
rs1357948460 3448 dbSNP
rs1275647331 3453 dbSNP
rs1215273237 3456 dbSNP
rs960294280 3461 dbSNP
rs1268472443 3466 dbSNP
rs6668796 3467 dbSNP
rs916229744 3471 dbSNP
rs148884654 3478 dbSNP
rs891687491 3488 dbSNP
rs1348048982 3493 dbSNP
rs1011834470 3507 dbSNP
rs1042857998 3508 dbSNP
rs1172390809 3510 dbSNP
rs143702625 3526 dbSNP
rs1418226894 3531 dbSNP
rs1378163526 3534 dbSNP
rs1190876418 3543 dbSNP
rs1481248448 3552 dbSNP
rs557258023 3566 dbSNP
rs1199157662 3568 dbSNP
rs1006634498 3574 dbSNP
rs74446856 3575 dbSNP
rs965023821 3578 dbSNP
rs993809689 3581 dbSNP
rs776603700 3582 dbSNP
rs952958506 3586 dbSNP
rs746878655 3593 dbSNP
rs1438571034 3594 dbSNP
rs567121048 3595 dbSNP
rs1036622497 3623 dbSNP
rs370116523 3623 dbSNP
rs1404136738 3625 dbSNP
rs1365160715 3627 dbSNP
rs1299644093 3632 dbSNP
rs1023800436 3649 dbSNP
rs1362114459 3652 dbSNP
rs761712395 3653 dbSNP
rs1167937741 3664 dbSNP
rs1177776765 3665 dbSNP
rs1429093712 3668 dbSNP
rs982146479 3669 dbSNP
rs1468584152 3676 dbSNP
rs1429599242 3680 dbSNP
rs1333712360 3687 dbSNP
rs151054731 3693 dbSNP
rs1431074623 3698 dbSNP
rs368866350 3703 dbSNP
rs1178135648 3705 dbSNP
rs749863585 3710 dbSNP
rs1326341325 3730 dbSNP
rs1480623983 3732 dbSNP
rs758094600 3733 dbSNP
rs141002524 3736 dbSNP
rs947323512 3739 dbSNP
rs1461792138 3744 dbSNP
rs1043316658 3748 dbSNP
rs889615510 3754 dbSNP
rs753111481 3755 dbSNP
rs942468421 3765 dbSNP
rs1321251850 3778 dbSNP
rs1220270711 3779 dbSNP
rs1224077293 3786 dbSNP
rs1258411550 3801 dbSNP
rs570717566 3804 dbSNP
rs1340379105 3807 dbSNP
rs1454142249 3810 dbSNP
rs117163130 3811 dbSNP
rs1043109207 3813 dbSNP
rs1464292547 3816 dbSNP
rs900893755 3837 dbSNP
rs999005924 3845 dbSNP
rs1036256141 3849 dbSNP
rs537536096 3852 dbSNP
rs1445740939 3855 dbSNP
rs1013170355 3857 dbSNP
rs1268808451 3858 dbSNP
rs1023254242 3866 dbSNP
rs1479721985 3867 dbSNP
rs778269918 3867 dbSNP
rs1216275015 3868 dbSNP
rs1316066974 3884 dbSNP
rs908937705 3891 dbSNP
rs534723367 3892 dbSNP
rs971866775 3894 dbSNP
rs1313810230 3900 dbSNP
rs552665931 3908 dbSNP
rs1005791314 3920 dbSNP
rs866266619 3921 dbSNP
rs969562850 3939 dbSNP
rs1359081825 3956 dbSNP
rs1165789589 3960 dbSNP
rs1392330546 3963 dbSNP
rs574377314 3970 dbSNP
rs188653155 3971 dbSNP
rs910472796 3973 dbSNP
rs1385096362 3980 dbSNP
rs947388017 3991 dbSNP
rs1035077980 3992 dbSNP
rs1186201996 3995 dbSNP
rs1487415546 3996 dbSNP
rs956750785 3997 dbSNP
rs749851882 4009 dbSNP
rs903214298 4010 dbSNP
rs1360086736 4011 dbSNP
rs557623467 4013 dbSNP
rs1242016867 4016 dbSNP
rs1057253957 4022 dbSNP
rs150180986 4022 dbSNP
rs1381341060 4032 dbSNP
rs1227039061 4035 dbSNP
rs1249845167 4037 dbSNP
rs1358650180 4040 dbSNP
rs1223366922 4048 dbSNP
rs1365543857 4051 dbSNP
rs895978220 4053 dbSNP
rs1013096847 4054 dbSNP
rs745930555 4055 dbSNP
rs757799036 4058 dbSNP
rs978684084 4067 dbSNP
rs1262953461 4071 dbSNP
rs1271249903 4071 dbSNP
rs1005856454 4074 dbSNP
rs1016329207 4084 dbSNP
rs779070834 4086 dbSNP
rs1208041114 4087 dbSNP
rs1369869770 4096 dbSNP
rs545963685 4104 dbSNP
rs564372222 4110 dbSNP
rs10801934 4124 dbSNP
rs1030046106 4125 dbSNP
rs772341248 4126 dbSNP
rs1405957468 4129 dbSNP
rs1330936558 4135 dbSNP
rs985947386 4138 dbSNP
rs540739329 4142 dbSNP
rs747215483 4149 dbSNP
rs1397823390 4158 dbSNP
rs947281148 4161 dbSNP
rs768484397 4163 dbSNP
rs929708554 4165 dbSNP
rs143308448 4167 dbSNP
rs1480217509 4172 dbSNP
rs1376897780 4178 dbSNP
rs574328799 4179 dbSNP
rs1046796268 4184 dbSNP
rs776383029 4186 dbSNP
rs529281125 4187 dbSNP
rs147126017 4193 dbSNP
rs569945817 4201 dbSNP
rs1314511696 4207 dbSNP
rs895904614 4214 dbSNP
rs948841972 4242 dbSNP
rs1023906414 4247 dbSNP
rs1219509912 4258 dbSNP
rs1343851996 4258 dbSNP
rs1006197494 4260 dbSNP
rs1273505571 4260 dbSNP
rs199668002 4260 dbSNP
rs769571913 4265 dbSNP
rs1261839596 4267 dbSNP
rs376288701 4270 dbSNP
rs530862791 4270 dbSNP
rs181007801 4271 dbSNP
rs1035149702 4272 dbSNP
rs570682119 4277 dbSNP
rs1400316514 4280 dbSNP
rs1170608819 4292 dbSNP
rs954477078 4296 dbSNP
rs375361518 4299 dbSNP
rs1177993907 4301 dbSNP
rs1364336356 4301 dbSNP
rs1437715593 4302 dbSNP
rs985873428 4303 dbSNP
rs1009594760 4305 dbSNP
rs1275988339 4307 dbSNP
rs1022742873 4309 dbSNP
rs979076649 4311 dbSNP
rs1441012785 4320 dbSNP
rs534659038 4324 dbSNP
rs1238655907 4330 dbSNP
rs553041090 4332 dbSNP
rs934615100 4337 dbSNP
rs986509495 4344 dbSNP
rs772794506 4357 dbSNP
rs1338930477 4359 dbSNP
rs992845661 4361 dbSNP
rs917310043 4365 dbSNP
rs1360974942 4369 dbSNP
rs564086479 4371 dbSNP
rs1417851714 4394 dbSNP
rs1363183909 4396 dbSNP
rs1451483961 4413 dbSNP
rs1183677257 4415 dbSNP
rs762304407 4443 dbSNP
rs1235403108 4449 dbSNP
rs1194939092 4455 dbSNP
rs1447181237 4462 dbSNP
rs1304425680 4464 dbSNP
rs1406507010 4466 dbSNP
rs948768899 4473 dbSNP
rs76183878 4485 dbSNP
rs1336307252 4487 dbSNP
rs556708498 4493 dbSNP
rs1271971823 4499 dbSNP
rs1431837353 4514 dbSNP
rs1340111534 4527 dbSNP
rs1297373024 4531 dbSNP
rs922421635 4532 dbSNP
rs1397839946 4533 dbSNP
rs1367410239 4534 dbSNP
rs941547141 4538 dbSNP
rs1037650338 4546 dbSNP
rs897424566 4555 dbSNP
rs114143357 4556 dbSNP
rs1169136122 4561 dbSNP
rs1046790301 4579 dbSNP
rs755471997 4590 dbSNP
rs1261944892 4606 dbSNP
rs369387985 4610 dbSNP
rs1490931208 4632 dbSNP
rs373273057 4647 dbSNP
rs1221533823 4667 dbSNP
rs941047152 4672 dbSNP
rs1316892671 4673 dbSNP
rs1275277952 4675 dbSNP
rs1237476581 4681 dbSNP
rs763287361 4686 dbSNP
rs1017340720 4690 dbSNP
rs1216596809 4694 dbSNP
rs1347212763 4701 dbSNP
rs1293862969 4703 dbSNP
rs905494020 4707 dbSNP
rs1003744256 4708 dbSNP
rs138459730 4712 dbSNP
rs1240885357 4729 dbSNP
rs1465627899 4736 dbSNP
rs1422510482 4737 dbSNP
rs1458784353 4739 dbSNP
rs1177300447 4743 dbSNP
rs1406584817 4745 dbSNP
rs1417290297 4747 dbSNP
rs1000032946 4749 dbSNP
rs1190965414 4750 dbSNP
rs1457336874 4750 dbSNP
rs36122376 4750 dbSNP
rs397710713 4750 dbSNP
rs552643810 4750 dbSNP
rs1429812000 4751 dbSNP
rs1469114717 4759 dbSNP
rs1205853334 4760 dbSNP
rs1173905929 4763 dbSNP
rs1404225317 4764 dbSNP
rs1444608741 4766 dbSNP
rs1301785918 4770 dbSNP
rs760765086 4774 dbSNP
rs149623565 4779 dbSNP
rs892618400 4785 dbSNP
rs540512919 4794 dbSNP
rs917235213 4800 dbSNP
rs1009668311 4801 dbSNP
rs183624995 4809 dbSNP
rs1175808247 4814 dbSNP
rs1431768506 4817 dbSNP
rs529398042 4821 dbSNP
rs544580641 4823 dbSNP
rs1410833881 4839 dbSNP
rs1179874452 4840 dbSNP
rs189472846 4860 dbSNP
rs1439587017 4873 dbSNP
rs1261600623 4881 dbSNP
rs144345884 4884 dbSNP
rs980150067 4885 dbSNP
rs761343068 4886 dbSNP
rs1007561567 4902 dbSNP
rs376942668 4903 dbSNP
rs909972327 4905 dbSNP
rs1018018343 4911 dbSNP
rs963989630 4912 dbSNP
rs1310168722 4921 dbSNP
rs181983015 4935 dbSNP
rs552504173 4954 dbSNP
rs570619946 4957 dbSNP
rs1286051946 4958 dbSNP
rs922451285 4961 dbSNP
rs1376047628 4963 dbSNP
rs918781498 4964 dbSNP
rs934229520 4964 dbSNP
rs187026310 4973 dbSNP
rs890114166 4975 dbSNP
rs191725244 4979 dbSNP
rs754205806 4980 dbSNP
rs556797252 4982 dbSNP
rs982991456 4992 dbSNP
rs1347354146 4994 dbSNP
rs909637774 4996 dbSNP
rs904287963 4998 dbSNP
rs1480047182 4999 dbSNP
rs1185502920 5002 dbSNP
rs1000405612 5007 dbSNP
rs1255763406 5009 dbSNP
rs1031489956 5025 dbSNP
rs540333859 5027 dbSNP
rs1486970255 5028 dbSNP
rs1265136254 5029 dbSNP
rs1217000447 5030 dbSNP
rs1425466999 5031 dbSNP
rs1283751476 5042 dbSNP
rs955880016 5044 dbSNP
rs941107424 5048 dbSNP
rs1024237004 5050 dbSNP
rs1354095031 5055 dbSNP
rs1393990533 5062 dbSNP
rs1363614890 5073 dbSNP
rs1044771861 5074 dbSNP
rs1399707928 5075 dbSNP
rs181737791 5078 dbSNP
rs374775928 5079 dbSNP
rs1368039218 5085 dbSNP
rs779219724 5105 dbSNP
rs1430537489 5110 dbSNP
rs962816072 5115 dbSNP
rs868391072 5116 dbSNP
rs973254147 5117 dbSNP
rs1404857303 5118 dbSNP
rs918761475 5119 dbSNP
rs934196905 5121 dbSNP
rs1488761930 5125 dbSNP
rs1264408057 5128 dbSNP
rs553502336 5129 dbSNP
rs1009746417 5130 dbSNP
rs1218429808 5133 dbSNP
rs911475388 5140 dbSNP
rs1387920114 5141 dbSNP
rs1038707220 5145 dbSNP
rs943012554 5145 dbSNP
rs775004518 5152 dbSNP
rs535230396 5170 dbSNP
rs1224111853 5174 dbSNP
rs1170298777 5177 dbSNP
rs185658569 5186 dbSNP
rs190071265 5195 dbSNP
rs903975650 5211 dbSNP
rs1490177442 5214 dbSNP
rs1008047990 5221 dbSNP
rs999928985 5224 dbSNP
rs1265133091 5225 dbSNP
rs1017645705 5239 dbSNP
rs1197668406 5239 dbSNP
rs1315669630 5243 dbSNP
rs901824350 5245 dbSNP
rs1234339567 5250 dbSNP
rs1331067555 5258 dbSNP
rs1053318914 5274 dbSNP
rs780155741 5275 dbSNP
rs1401178796 5276 dbSNP
rs1475625791 5278 dbSNP
rs997492671 5286 dbSNP
rs1029595879 5291 dbSNP
rs1185646243 5292 dbSNP
rs891626497 5294 dbSNP
rs1419110559 5302 dbSNP
rs1014098977 5303 dbSNP
rs1024204549 5321 dbSNP
rs905792724 5323 dbSNP
rs1441432647 5336 dbSNP
rs1366243779 5337 dbSNP
rs1424664982 5338 dbSNP
rs1238327948 5339 dbSNP
rs539695506 5340 dbSNP
rs1301824172 5341 dbSNP
rs951240624 5345 dbSNP
rs982678457 5347 dbSNP
rs1347405678 5349 dbSNP
rs1017173221 5351 dbSNP
rs1280253142 5351 dbSNP
rs1431941239 5357 dbSNP
rs1201412636 5359 dbSNP
rs115155571 5370 dbSNP
rs1359460053 5374 dbSNP
rs963074133 5379 dbSNP
rs1247675411 5382 dbSNP
rs561762410 5384 dbSNP
rs1378282586 5387 dbSNP
rs1308637429 5405 dbSNP
rs1444565939 5413 dbSNP
rs926351701 5413 dbSNP
rs1335040564 5417 dbSNP
rs1358088154 5417 dbSNP
rs1219545858 5419 dbSNP
rs1286263167 5423 dbSNP
rs1025693565 5426 dbSNP
rs1170589731 5430 dbSNP
rs939034160 5435 dbSNP
rs1447467916 5443 dbSNP
rs747268347 5444 dbSNP
rs534383036 5448 dbSNP
rs865830001 5451 dbSNP
rs1437227755 5457 dbSNP
rs945616928 5459 dbSNP
rs555719289 5467 dbSNP
rs1254590541 5468 dbSNP
rs762370213 5468 dbSNP
rs1219170351 5475 dbSNP
rs1043933242 5479 dbSNP
rs1355051979 5489 dbSNP
rs1285878034 5495 dbSNP
rs377639546 5498 dbSNP
rs757971658 5498 dbSNP
rs904006052 5500 dbSNP
rs1280060584 5501 dbSNP
rs1338913412 5504 dbSNP
rs148421188 5505 dbSNP
rs1039153411 5509 dbSNP
rs1401576503 5519 dbSNP
rs768830295 5520 dbSNP
rs1354946481 5521 dbSNP
rs1297559142 5526 dbSNP
rs1398851056 5528 dbSNP
rs768115013 5529 dbSNP
rs1410844439 5531 dbSNP
rs1472270981 5540 dbSNP
rs1366277600 5545 dbSNP
rs572259136 5547 dbSNP
rs980114932 5550 dbSNP
rs544401892 5564 dbSNP
rs1262891256 5573 dbSNP
rs1026319093 5574 dbSNP
rs1215133869 5576 dbSNP
rs1318132955 5578 dbSNP
rs1453828182 5582 dbSNP
rs1343800345 5585 dbSNP
rs1290750846 5587 dbSNP
rs1227754050 5603 dbSNP
rs1354547972 5605 dbSNP
rs1454300144 5607 dbSNP
rs77206269 5612 dbSNP
rs887069325 5613 dbSNP
rs1004525640 5626 dbSNP
rs1297353710 5628 dbSNP
rs1428624734 5629 dbSNP
rs1016793973 5635 dbSNP
rs780991761 5636 dbSNP
rs1381499920 5640 dbSNP
rs546129728 5656 dbSNP
rs562823752 5659 dbSNP
rs1280735247 5660 dbSNP
rs1351367166 5662 dbSNP
rs1223110614 5669 dbSNP
rs578077071 5682 dbSNP
rs1219001286 5687 dbSNP
rs980602006 5690 dbSNP
rs1172431442 5696 dbSNP
rs545458330 5697 dbSNP
rs1033398336 5700 dbSNP
rs1477924737 5703 dbSNP
rs1325409099 5706 dbSNP
rs960407148 5708 dbSNP
rs576623954 5711 dbSNP
rs891570773 5719 dbSNP
rs1220957413 5730 dbSNP
rs949836854 5730 dbSNP
rs1449990847 5732 dbSNP
rs1243984465 5741 dbSNP
rs1461009679 5745 dbSNP
rs1045578689 5746 dbSNP
rs913561219 5752 dbSNP
rs1212525699 5758 dbSNP
rs1369674841 5759 dbSNP
rs945676873 5765 dbSNP
rs747883778 5784 dbSNP
rs753438750 5786 dbSNP
rs550877194 5788 dbSNP
rs1470836556 5790 dbSNP
rs1001458461 5791 dbSNP
rs980073970 5797 dbSNP
rs925532907 5798 dbSNP
rs1399022778 5803 dbSNP
rs564367881 5821 dbSNP
rs898464577 5824 dbSNP
rs994576598 5829 dbSNP
rs1453115397 5833 dbSNP
rs1471162519 5841 dbSNP
rs1039184872 5846 dbSNP
rs1240170887 5849 dbSNP
rs1025657683 5854 dbSNP
rs76800110 5863 dbSNP
rs933386516 5871 dbSNP
rs986873065 5872 dbSNP
rs1202207041 5883 dbSNP
rs1018378610 5884 dbSNP
rs1279028395 5902 dbSNP
rs769777861 5908 dbSNP
rs1047792115 5913 dbSNP
rs546756587 5916 dbSNP
rs1446792776 5917 dbSNP
rs886423558 5922 dbSNP
rs1006198731 5926 dbSNP
rs1038706053 5928 dbSNP
rs1375722016 5929 dbSNP
rs964598433 5930 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgGGAGGGGACUGAGGGACu 5'
            || |:|:|  ||||||| 
Target 5' --CCCCUCUUCCCUCCCUG- 3'
 		1 - 17
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000369466.4 | 3UTR | CCCCUCUUCCCUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
146 hsa-miR-4270 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT056076 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 2 2
MIRT057833 SLC30A7 solute carrier family 30 member 7 2 2
MIRT109295 TXLNG taxilin gamma 2 2
MIRT117521 MIDN midnolin 2 2
MIRT183504 BTG2 BTG anti-proliferation factor 2 2 2
MIRT258346 HOXA11 homeobox A11 2 6
MIRT275743 TFDP1 transcription factor Dp-1 2 2
MIRT284426 CAPN15 calpain 15 2 2
MIRT386430 CCL22 C-C motif chemokine ligand 22 2 2
MIRT443374 PLXNA2 plexin A2 2 2
MIRT445251 SEMA5A semaphorin 5A 2 2
MIRT445767 CCND3 cyclin D3 2 2
MIRT447231 ABI2 abl interactor 2 2 2
MIRT451224 ZNF444 zinc finger protein 444 2 2
MIRT451433 TJP3 tight junction protein 3 2 4
MIRT451959 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452006 FKBP5 FK506 binding protein 5 2 2
MIRT452300 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT452717 DTHD1 death domain containing 1 2 2
MIRT453361 ZNF3 zinc finger protein 3 2 2
MIRT453458 GLG1 golgi glycoprotein 1 2 2
MIRT453832 SAA1 serum amyloid A1 2 2
MIRT453928 COMMD5 COMM domain containing 5 2 4
MIRT454312 ZNF134 zinc finger protein 134 2 2
MIRT454493 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454836 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT455142 TBC1D25 TBC1 domain family member 25 2 2
MIRT455922 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT456163 TTF2 transcription termination factor 2 2 2
MIRT456395 KLHL12 kelch like family member 12 2 2
MIRT456786 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT457164 MXRA7 matrix remodeling associated 7 2 2
MIRT457190 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT457415 RPL36 ribosomal protein L36 2 2
MIRT457630 UPK3BL uroplakin 3B like 1 2 2
MIRT458720 VPS39 VPS39, HOPS complex subunit 2 2
MIRT458745 CES2 carboxylesterase 2 2 2
MIRT459269 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT459490 CCL11 C-C motif chemokine ligand 11 2 2
MIRT460319 SH3RF1 SH3 domain containing ring finger 1 2 2
MIRT461005 SYT7 synaptotagmin 7 2 2
MIRT461579 SCO1 SCO1, cytochrome c oxidase assembly protein 2 4
MIRT461820 SNAP23 synaptosome associated protein 23 2 2
MIRT463332 ZFHX3 zinc finger homeobox 3 2 2
MIRT463449 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464272 VCL vinculin 2 2
MIRT464895 UBALD1 UBA like domain containing 1 2 2
MIRT465556 TOB2 transducer of ERBB2, 2 2 2
MIRT466360 THBS1 thrombospondin 1 2 2
MIRT466956 STAT3 signal transducer and activator of transcription 3 2 2
MIRT467321 SPATA2 spermatogenesis associated 2 2 2
MIRT467440 SND1 staphylococcal nuclease and tudor domain containing 1 2 2
MIRT467823 SLC29A2 solute carrier family 29 member 2 2 2
MIRT471173 PHB2 prohibitin 2 2 2
MIRT471397 PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2 2
MIRT471754 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 2
MIRT471846 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT472020 NPTXR neuronal pentraxin receptor 2 2
MIRT472224 NGFR nerve growth factor receptor 2 2
MIRT472439 NBL1 neuroblastoma 1, DAN family BMP antagonist 2 2
MIRT472541 NACC1 nucleus accumbens associated 1 2 2
MIRT473195 MINOS1-NBL1 MINOS1-NBL1 readthrough 2 2
MIRT473211 MINK1 misshapen like kinase 1 2 2
MIRT473668 MARCKSL1 MARCKS like 1 2 2
MIRT474852 KHSRP KH-type splicing regulatory protein 2 2
MIRT474939 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT477330 EPHA2 EPH receptor A2 2 2
MIRT477395 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT477466 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT477974 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 2 2
MIRT478331 DDN dendrin 2 2
MIRT479481 CDK2 cyclin dependent kinase 2 2 2
MIRT481212 ATXN7L3B ataxin 7 like 3B 2 2
MIRT481263 ATXN7L3 ataxin 7 like 3 2 2
MIRT481409 ASXL1 additional sex combs like 1, transcriptional regulator 2 2
MIRT482051 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT482396 AEN apoptosis enhancing nuclease 2 2
MIRT483160 PCSK2 proprotein convertase subtilisin/kexin type 2 2 7
MIRT483370 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT483520 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 4
MIRT484059 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT487075 CLASP1 cytoplasmic linker associated protein 1 2 4
MIRT487421 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT488359 PAX2 paired box 2 2 2
MIRT488592 ST7L suppression of tumorigenicity 7 like 2 2
MIRT489556 SOX11 SRY-box 11 2 4
MIRT489804 KRT80 keratin 80 2 4
MIRT489865 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 2 2
MIRT490014 KIFC2 kinesin family member C2 2 2
MIRT490036 PCSK4 proprotein convertase subtilisin/kexin type 4 2 2
MIRT491070 ACVR1B activin A receptor type 1B 2 2
MIRT494016 DUSP9 dual specificity phosphatase 9 2 2
MIRT494816 AKAP11 A-kinase anchoring protein 11 2 2
MIRT495991 LTBP2 latent transforming growth factor beta binding protein 2 2 2
MIRT496272 SLC2A13 solute carrier family 2 member 13 2 2
MIRT500454 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT507989 BCL2L13 BCL2 like 13 2 4
MIRT509713 ANKRD23 ankyrin repeat domain 23 2 2
MIRT527984 TSLP thymic stromal lymphopoietin 2 2
MIRT530448 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT531235 FANCC Fanconi anemia complementation group C 2 2
MIRT534590 RPL28 ribosomal protein L28 2 2
MIRT535990 MED28 mediator complex subunit 28 2 4
MIRT537280 GABRA5 gamma-aminobutyric acid type A receptor alpha5 subunit 2 2
MIRT539924 DUSP28 dual specificity phosphatase 28 2 2
MIRT554711 RNF146 ring finger protein 146 2 2
MIRT558962 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 2
MIRT568497 ARHGDIA Rho GDP dissociation inhibitor alpha 2 2
MIRT568875 LY6H lymphocyte antigen 6 family member H 2 2
MIRT568987 CACNA1C calcium voltage-gated channel subunit alpha1 C 2 2
MIRT569990 TMEM184A transmembrane protein 184A 2 2
MIRT570485 THRA thyroid hormone receptor, alpha 2 2
MIRT572826 MYO1C myosin IC 2 2
MIRT608199 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT613220 CCDC85C coiled-coil domain containing 85C 2 4
MIRT629782 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT635332 RASSF4 Ras association domain family member 4 2 2
MIRT653632 SLC30A3 solute carrier family 30 member 3 2 2
MIRT664572 GUF1 GUF1 homolog, GTPase 2 2
MIRT667855 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668820 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT671274 ETFDH electron transfer flavoprotein dehydrogenase 2 2
MIRT681448 CIITA class II major histocompatibility complex transactivator 2 2
MIRT684817 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT685861 ANGEL1 angel homolog 1 2 2
MIRT688812 CAPZB capping actin protein of muscle Z-line beta subunit 2 2
MIRT691198 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT696947 CERK ceramide kinase 2 2
MIRT699741 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT701259 NUP35 nucleoporin 35 2 2
MIRT701935 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT703332 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT705519 ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 2 2
MIRT706065 PKD1 polycystin 1, transient receptor potential channel interacting 2 2
MIRT713238 SV2B synaptic vesicle glycoprotein 2B 2 2
MIRT714670 CHRNE cholinergic receptor nicotinic epsilon subunit 2 2
MIRT715001 TSPAN11 tetraspanin 11 2 2
MIRT715356 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT715971 FADS3 fatty acid desaturase 3 2 2
MIRT719585 FNBP4 formin binding protein 4 2 2
MIRT719667 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT723360 ASCL2 achaete-scute family bHLH transcription factor 2 2 2
MIRT734985 GADD45A growth arrest and DNA damage inducible alpha 2 0
MIRT735022 MMP19 matrix metallopeptidase 19 3 0
MIRT737359 SATB2 SATB homeobox 2 3 0
MIRT756223 MCM3 minichromosome maintenance complex component 3 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miR-4270 Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4270 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4270 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (total RNA)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-4270 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-4270 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4270 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4270 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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