miRTarBase - #MIRT456496


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pre-miRNA Information
pre-miRNA hsa-mir-2110   
Genomic Coordinates chr10: 114174105 - 114174179
Synonyms hsa-mir-2110, MIR2110
Description Homo sapiens miR-2110 stem-loop
Comment Zhu et al. incorrectly referred to this sequence as mir-1309 in . This sequence is unrelated to MIR1309 in plants.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-2110
Sequence 8| UUGGGGAAACGGCCGCUGAGUG |29
Evidence Experimental
Experiments 454
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN31660996 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1434681640 4 dbSNP
rs1418383763 6 dbSNP
rs745914474 7 dbSNP
rs1178383827 8 dbSNP
rs1412803607 9 dbSNP
rs114530801 10 dbSNP
rs1168982220 11 dbSNP
rs573692968 14 dbSNP
rs1246581316 15 dbSNP
rs1431021422 16 dbSNP
rs1188283086 17 dbSNP
rs1476834649 19 dbSNP
rs192664871 19 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PFKFB2   
Synonyms PFK-2/FBPase-2
Description 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Transcript NM_006212   
Other Transcripts NM_001018053   
Expression
Putative miRNA Targets on PFKFB2
3'UTR of PFKFB2
(miRNA target sites are highlighted)		 
>PFKFB2|NM_006212|3'UTR
   1 CCGAAGACCCAAGTCAGCATTCCGGTGGTGTAACTGTGTGTTTCCCTCCAGCCCTGGCCTCCTGCCCTTGTCACTAATCA
  81 CCAAGGAGTCATTAACTTCCTCCCTCTATGCCCACCCCTGACACTTCACCATTAATCTTAACACAGAACATGAGGTTATG
 161 TGTTTATAGGACAACTTAAGCTGTTCTTCAGTTTGAAACATCTTTTCACCCAGGGGCAAGTTAGCAAATTGAGTCTTTTA
 241 GGACAGATTCTCAGATGGGATGATCTGGAGGAGGAGGAAAAAGATACACTCCCTTGGGGCTGAGCATGCCCCACACTCTT
 321 GGATCTTCTCTCTGTTCCCTGGTGTCTTCACTAATGTCCTCATGTTGGTGAAGTGTTGGGGGATGGAGGGCGGGTGAGCA
 401 GTCGGGGGACAAAAAGTCTATTTTTCCTTCACTTTTGTCTCTTCAATGTGTGTTTTCCTCACACTCCTTACTTGACTGCT
 481 TTCTTCCCCCACTTTCATGTCCCCTCTGGATTGTCCAGTGTAATGCATGGCATTGTGGTGTCTGTCTAGGAAGGAAGGGG
 561 TGATTGACAAGAGACAAGTCTGGCCCAGTTAATGCTTTCTGCAGTGGGTCTAAATGGATCTGGACTGGAGGAGTCTTTCC
 641 TTTCCTTTCTCCCTTCCTCTCCAGCCAGGTCCTGTAAGGGCCAGCCCAGACTACAGGACATCCACAGAATATTCTGGAGC
 721 TTGCAAGTAGACATAGGGTGAGAGTTCTTGCCTCCTTTCATGAGAAACAGTTCTAAGTCTTCGATGCCCTGGGAGAATCT
 801 GGCTCTGAGCATGTGGGAAATGTCTTGGTTTTTATTTTTAATTTAGAGTCAGGCCTGGGTCTTTTGAGGTCTGCAGAGTG
 881 GGGTTTAGGAGAGTAGGGTGGGCTCTAGCTCTTGCAGGGCTCTTAGAGAGCAGTCATGTCTTTTCTCCCATGACTCTCAG
 961 GTTCTTTGCCAATCACAGCAACTTTTCCTGCCAAAGCCAGTATCCTCTGGGGCTGTTTAGAAGGGCAGTTAGATTCAGGA
1041 GTCACCACTGATGTTTGAGTTGCTCAAGGCAAGAGGCAGAGAAGAGTTCACTAAAACTGCTTATTTTTGAATAATTTCAG
1121 CACACTGTCCTTAAGAAGAAAGAAACATCAAAACAAAATAGTTTTTACATGACCATTTTTTTCCCAAATGTGGAAAAGCT
1201 TGATGATGAATTTAATCTCTCTCATTGGAGTATTCTTTTGTTCATAAAGAGAAACTATCTCATCTTGATGTCCAGAGAAG
1281 TCCTTGGAACCCTGTGGGATCTAGCTCGTAACTGTTTGTATTTCTCTATTCACTTCTGTCATTTCATTTTCTTTGTAGGG
1361 TTAAACAGAAAATGTTTAGGGAAGAAATTCTTAGCCCCTTGATGACCATGATGGCTTATTCTCTTTCCCAATTTTGCATG
1441 CAAAATGTACGAATATATGTATGTTTTTCTGAGAGGCAAGTTTAGGGTTCTCATGGGATTTTAAAAAGAGATAGGTGACT
1521 CCCCACCTTAAAGTTATCTGCTGGTCTTTTAGAGGTAACCAGTGAGAAGGAGTTAGCTATTTTCCAAGGGTGTTTTCATT
1601 TGGTAATGGAAGACTTTTTGCTGTGGTTCTCATCCAGGAGTATTCCTTAGAATTGCCTTTAGGATTGTTGAATCATAAAC
1681 ATGCCTGTGTCCACCTTATGCTTAATACTGACTCAGAATCTCTGGGATCTGGGTCTGGACATGCATGTATTTAAGTAGCT
1761 TCCCGGATGATTCTGATTCATAGCTCGGGTTAAGAACTCCACCTTAGGAAGTTAGGTGGAAAAATACTGGATAGTAGTTT
1841 CTCAGACAAAAGTGTCAGCCTAGGAATTCTGAATTCCTCATAGTCCTGAAAGGACAGTTCTTTGGGTTTGATGTTTGAGC
1921 AGATCATAATGTTAAATGATATAACCCCCTGGAAGGCAGGCTGCTGTGTTTTAGAGGGTTATTCTAGGTTCTAGTCCCAT
2001 CTTTAACCCTTTACATTGCTGAGTGATGTGGAACAAATCACTGAATTAAATAATTGTCTCTAGAGAGCAGCTGGGGATTT
2081 TAAGCACCCTGGAGAGAGGTGCAGACCCTGCCAGGATGATAAAGGTTGTCATCACTGGCAACTGACTCCTGACCCCGGGT
2161 CCTTTACTCGTATGTCCCAAGTAGGATACCATAGGCAGCTTCTAAAGGCTGCTTACCTAGATTCTTCTCAAAATTGTGTC
2241 CAAGATGTTAAGTAACCTGCTATTCCTGTTTAGTGGTTACATAACATGTACTTAGTGTCTTTGTGGAGCTTTGGGCTGGT
2321 AGGGGCAGGGATAGGGGAAAGCTAAACAGAAGTAGAAGAAAAGGTCCTTGTCCAGAGGAAGGTTATTTTAAGAGACAGGA
2401 CATGTAATTTATAACAAATGGACATTTGCAATATAGCAACAGTCTGAGTCTAGAAGTGTTCAACCATCACATCGCTTCTC
2481 CTGACTTTTCTGTTGTCCTATGGCTATGAGACTACAGGGGTTGGGGGATGGGGATGCCCCCACCACCACCAGTGTGAGAA
2561 TGAGATATGGTTGGGGAGGCGTGTTTGGCACTTTTACAAGGTTGCATTGTCCACATTTGCTTGGATGGTGGCATCTGTAG
2641 CCCAAATGGGCATTCAGTCTTTTCTTCTGCTGTGAGGTAAGAGTAATTCAGACCTAATGAATGAGAAGAGGGAGCACTTT
2721 GATCCACAGACTTTGGATTAACACTGTACCCACTCTTAGCAAAAGGGGACTTCTCTAACAAGCTAGCATTGTGTTAACCT
2801 GTCATTAACCCAGCATTAGAGACAGGTCACTGGGATGTTCATTCTGGCTCTCAGCCTGCTGTTATTTCCCCACTCTCACC
2881 TGTGCTAGTTCGCTTTCTCCAGAAGAGGAGCTGAGGTGGTCTTATCCTCAGATAGGACATGAGAAATTGGAATTTGGCAA
2961 GCAAGGGCTTCAGCATCCTTTAGTTTCTAAAGCAAGATCCCTTCAGAGAAGTCTAGCAGGAAGAAGCCAGGAGAATGTAG
3041 AATGGAAAAGAGCTCTTACTCCAAATTTTAGAGAAGTTTCAGCTCTACTTCTCATCTTTTCTCTCCTGGTCTTACTTGAA
3121 TGCATGTTGGTAATCTGTATACATTACTATGACTGTGTCTATCACAAGTCCTACAAAATAAAAATGGACTTAAAAGTACT
3201 CTCTGCTGAGGCTGTAAGTTTTGTTTTGTGAGAAATAGGTAAAGACATTAGCATTTAATCTACTGGAATAAGCTGGTTGC
3281 TGTGGCTTATACCTGTAGTCCCAGATACTTGGGAGGCTGAGGCAGGAGAATCACTTGAGACCAGCCTGGGCAATATAGTG
3361 AGACCTCACCTCTAAAAAAGTTTTTTATAAATTTACTTGTCTAAAGTGGGGAAAGGGAAATTATTCTGTTTTCTTATTCT
3441 TGCTTCAAGACTATGACAGATTTGAAAGAGAATTCTAAAGCAGATTTAGAGAACCTGCTTCTCTTCTTATCTCCTAATCC
3521 CTAAATTGTAATTTAGCTCTTATCTGTATTGTTGTTTTGTTTTGGTAAAGGGATGATTTTTACATTGAGTTTTAAAGTAG
3601 AATAAGAAAAGCTTCTAAAAACTTGCATTGTGCTAGGGATCTGCCCTATATCTTTGCCTCTGGTGTTTCGTTGTTGTTGT
3681 TATTGTTTGTTTGTTTCCAAAGAAGTTGGAGTTAAGGACACAATATATTTGTACCCCTAGACTGAATGGGTGAGTATTCC
3761 ATATGAGGATCTGGGTAATCCTCTTTGCAACCCACATTTGGTCTTCAGAGACACTGGCATTTTGAAGAAACATATGATAT
3841 AGCTGTTTGGAAATAAATTCATCTATGTTACTTTTTTTTTCTTTTTTTTTTTTTTTTATGAGCAGGAGATCTTAATTGAC
3921 AGAAACTCATTGGTGGTTGGAGTGGCCAATGGGCACGGGAAAAAGTATCCAGTAATCAGAAGAATTGTATCTGGGTTATG
4001 TAATCTTATGCACATTCCATTGTCTTTGCCAAGCCCAGAAGCCATGTTGTGTTCATTGTTAAGAAATTTGATAGATTTAC
4081 CCAGCTTTTCTATGTATTTTGACTTATTGAAAATATGTAACAACTGAGTCGGGTTGCAGCACTGGTGGGGTAGAATCGAC
4161 TTTCCCTGAAGGTGACACAGATGTCAGAATTGTGTCCAGGGATTTAATTTAGACCCATACTGTCCAGGAGACTGTCTCTA
4241 GTTGGATCTCTGTGCTGACTGACTGACAGACAGACTTTAGTGTCTGTGTGCTGACTGACAGACTCTAGTAGTGTCTATAT
4321 GTTGACCAACTGGTAGACCAGGAGGATCTGTGTGCTGATTGACTCTAGTAGGATCTGTTTGTCACTGACAGACTGTAGTA
4401 GTGTCTGTGTGCTGACTGATAGATAGACTATAGTAAAATTTGGGTGTTGCCTGACTAACGGTCTAGGGTCTGTAAGCTGA
4481 CAGTCTGCCTGCTTTCTGATTGTATCCATTGAAGTGTATGTACATTATGGTAATTCTCTGTCTATTAAATGTGTCTAACA
4561 AAGGAAGGAATTAAGCACTCCACGTGTTTTCTTTATAGGGGAGTTCTGTACACTATGATTTTAAATAGATATTTCTTATA
4641 TAGTAGTGGCCAAATTCTCATTATTTTGTACAAGATAAAGGTTATGCATCACTTTTATGGTATTTTGTGAACTCAGCTAA
4721 GGGAATGCCTGTTCAGAGCCTGGAGTTGTTACCTTTACTTGAAGTCATCTCATCCAGTCCCCTGCTTTAGGGCAGGACTT
4801 CAGTTCCACTGTTCATTTCTGAAGCTTCTGTGTCCCCAGCTTACCCTGTTCTGAAATGTTGTATTCCATTGGACAGGGCT
4881 GCTATTTTTAGTCAGCCATGCATTTGGATTTTACACTTAATCTAGTAAGTAAAAATGAGAAGAAAATTTGGCATTTAAAA
4961 ATTGATTTTAAGGGTTGGCAAAAGTATTTTTTCCAGTAAGCCTTTCACTGGATATCTGTGACCAATGTTTACCTACGCAA
5041 TGTTTTTGTATCTGAATTGCTTATGTACGTTTTTTATTATATTGACCTAACAAGAAGATCAACTTATGCTGGTATGGTGA
5121 TGGTTTTGCTATGGCAAAATCAAAGGGCTGATCATACATGGTGCCCTTTGGGAAGGGGGATGGTGTGGGGCTGAGCACCT
5201 CTGGGTTGAATGGGAATGGGTCAGATTGGGAAGCCTAGGAAGAGAGTTCTACTGTAGATTTCCTAGGCACTGCTCTGTTG
5281 AAATAGGAACATAAGTCTTTAGCAACATTCTGATTTAATCGGGTGACACTGATAACAAAGTATGCCACTCAGATCCATTT
5361 AAAGTGTGCATAACTGTATTTGAAATGTGTTTTTGTGTGCGTGTGTGTAGAATGGGTAAATAAAATTGTTGAGTAACTTG
5441 AACCTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guGAGUC-GCCGGC---AAAGGGGUu 5'
            ||||| | ||:|   |||||||| 
Target 5' ctCTCAGCCTGCTGTTATTTCCCCAc 3'
 2848 - 2873 168.00 -23.90
2 
miRNA  3' guGAGUCGC-CGGCAAAGGGGUu 5'
            :||| :| |:  |||||:|| 
Target 5' tcTTCAATGTGTGTTTTCCTCAc 3'
 440 - 462 140.00 -12.80
3 
miRNA  3' guGAGUCG--CCGGC-AAAGGGGUu 5'
            ||  ||  | :|| ||||:||| 
Target 5' acCTGTGCTAGTTCGCTTTCTCCAg 3'
 2878 - 2902 138.00 -13.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30187925 3 COSMIC
COSN13512258 24 COSMIC
COSN30184689 24 COSMIC
COSN20073735 45 COSMIC
COSN20576583 62 COSMIC
COSN30460191 62 COSMIC
COSN30166081 128 COSMIC
COSN6020186 159 COSMIC
COSN28088827 428 COSMIC
COSN22887866 884 COSMIC
COSN18963893 1081 COSMIC
COSN16493605 1146 COSMIC
COSN6020187 1561 COSMIC
COSN20095893 1762 COSMIC
COSN6020188 2516 COSMIC
COSN1096818 2626 COSMIC
COSN1427928 3045 COSMIC
COSN16563916 3122 COSMIC
COSN18723807 3306 COSMIC
COSN20090444 3781 COSMIC
COSN20090445 3882 COSMIC
COSN18928011 3898 COSMIC
COSN7199595 4012 COSMIC
COSN27374367 4304 COSMIC
COSN20090447 4318 COSMIC
COSN20090448 4320 COSMIC
COSN20090449 4323 COSMIC
COSN32064969 4559 COSMIC
COSN9057554 5101 COSMIC
COSN8637380 5205 COSMIC
COSN6020189 5217 COSMIC
COSN30165502 5276 COSMIC
COSN8637381 5298 COSMIC
COSN31487452 5321 COSMIC
COSN31519668 5353 COSMIC
COSN26568211 5401 COSMIC
rs1060286 4585 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs778828027 3 dbSNP
rs747927978 4 dbSNP
rs1419930509 10 dbSNP
rs1049469166 16 dbSNP
rs1409210268 18 dbSNP
rs1169999309 22 dbSNP
rs771795023 24 dbSNP
rs769483356 25 dbSNP
rs746092429 26 dbSNP
rs769907023 31 dbSNP
rs1327165010 35 dbSNP
rs777797262 35 dbSNP
rs1451057285 36 dbSNP
rs775616682 40 dbSNP
rs763423694 48 dbSNP
rs1475645922 60 dbSNP
rs1167264623 64 dbSNP
rs775425231 67 dbSNP
rs1443185508 75 dbSNP
rs1010779989 85 dbSNP
rs916466870 90 dbSNP
rs1326912649 92 dbSNP
rs1375949742 93 dbSNP
rs1043948658 96 dbSNP
rs762644843 100 dbSNP
rs1046040556 103 dbSNP
rs886230979 109 dbSNP
rs772387449 112 dbSNP
rs368203997 116 dbSNP
rs1230724313 119 dbSNP
rs1299253995 121 dbSNP
rs35255963 125 dbSNP
rs1399199449 132 dbSNP
rs1061958 135 dbSNP
rs960966731 152 dbSNP
rs534266400 154 dbSNP
rs1213485121 163 dbSNP
rs1346235661 184 dbSNP
rs996059673 185 dbSNP
rs1224593070 211 dbSNP
rs1390059099 212 dbSNP
rs1012288541 218 dbSNP
rs1441483219 221 dbSNP
rs1023640832 226 dbSNP
rs184432317 234 dbSNP
rs1281108678 243 dbSNP
rs76197836 253 dbSNP
rs984961081 253 dbSNP
rs1374671291 257 dbSNP
rs1159531461 260 dbSNP
rs908016371 264 dbSNP
rs1320610023 268 dbSNP
rs773393216 269 dbSNP
rs890025441 275 dbSNP
rs1475215814 282 dbSNP
rs145281846 285 dbSNP
rs1190778870 288 dbSNP
rs6667268 289 dbSNP
rs1237291017 290 dbSNP
rs1216903719 293 dbSNP
rs966792775 296 dbSNP
rs999581904 303 dbSNP
rs1335631170 307 dbSNP
rs111977500 308 dbSNP
rs1354686207 309 dbSNP
rs933613156 309 dbSNP
rs991048877 311 dbSNP
rs1049417639 312 dbSNP
rs1289258317 313 dbSNP
rs191850113 316 dbSNP
rs1486161101 331 dbSNP
rs1190340225 333 dbSNP
rs1432551457 342 dbSNP
rs1343085555 345 dbSNP
rs11120138 351 dbSNP
rs946431606 352 dbSNP
rs1419439299 353 dbSNP
rs780117726 354 dbSNP
rs907517236 358 dbSNP
rs902317270 359 dbSNP
rs999466810 363 dbSNP
rs184869891 373 dbSNP
rs1476628772 376 dbSNP
rs555223821 379 dbSNP
rs1460894939 385 dbSNP
rs1240719289 391 dbSNP
rs189210736 392 dbSNP
rs1056744865 393 dbSNP
rs1275147748 400 dbSNP
rs540999189 404 dbSNP
rs1296135328 405 dbSNP
rs920323438 406 dbSNP
rs931531677 409 dbSNP
rs1050346219 413 dbSNP
rs1441208872 421 dbSNP
rs1396173436 428 dbSNP
rs896497930 441 dbSNP
rs765644879 447 dbSNP
rs1023586755 449 dbSNP
rs1171816507 458 dbSNP
rs952152897 459 dbSNP
rs1430784769 461 dbSNP
rs1006246946 464 dbSNP
rs1417880272 469 dbSNP
rs1015112802 473 dbSNP
rs1454891858 487 dbSNP
rs1377944655 488 dbSNP
rs117981509 490 dbSNP
rs1191839660 491 dbSNP
rs1488229818 494 dbSNP
rs1297069498 495 dbSNP
rs1251959940 498 dbSNP
rs1206587227 500 dbSNP
rs999509623 505 dbSNP
rs758656378 508 dbSNP
rs1273688828 511 dbSNP
rs1234668464 513 dbSNP
rs1032458105 519 dbSNP
rs958356926 521 dbSNP
rs1012123618 526 dbSNP
rs1373481622 529 dbSNP
rs777510017 531 dbSNP
rs923555400 541 dbSNP
rs953608521 545 dbSNP
rs1464001756 557 dbSNP
rs985148411 559 dbSNP
rs192590868 560 dbSNP
rs946462945 567 dbSNP
rs1168353028 576 dbSNP
rs751211376 581 dbSNP
rs981968269 586 dbSNP
rs550012219 590 dbSNP
rs961715091 594 dbSNP
rs935126080 601 dbSNP
rs145022644 608 dbSNP
rs1251396732 609 dbSNP
rs896443930 610 dbSNP
rs570940450 628 dbSNP
rs1045072334 632 dbSNP
rs1049932607 641 dbSNP
rs1277889682 649 dbSNP
rs1232147007 653 dbSNP
rs185645594 670 dbSNP
rs112721961 675 dbSNP
rs1317092917 677 dbSNP
rs1006309928 681 dbSNP
rs1389104673 690 dbSNP
rs944289998 691 dbSNP
rs552195030 718 dbSNP
rs1015391066 728 dbSNP
rs1415930730 733 dbSNP
rs1041344449 734 dbSNP
rs189580921 739 dbSNP
rs1465749489 744 dbSNP
rs935381549 752 dbSNP
rs1161394500 758 dbSNP
rs1054194448 759 dbSNP
rs1411325620 761 dbSNP
rs998134673 763 dbSNP
rs1453985466 773 dbSNP
rs1486600392 780 dbSNP
rs534485055 783 dbSNP
rs1199628759 784 dbSNP
rs953639584 785 dbSNP
rs1012714710 803 dbSNP
rs769829151 825 dbSNP
rs1023484532 843 dbSNP
rs1262060163 847 dbSNP
rs1236413734 856 dbSNP
rs1327945065 857 dbSNP
rs1293332515 871 dbSNP
rs906397534 874 dbSNP
rs372880218 876 dbSNP
rs986353905 882 dbSNP
rs1304095581 905 dbSNP
rs547745272 912 dbSNP
rs1017972835 915 dbSNP
rs1386118195 921 dbSNP
rs1290925514 926 dbSNP
rs1451859886 929 dbSNP
rs1014826159 934 dbSNP
rs1165689810 938 dbSNP
rs961932390 941 dbSNP
rs967666596 951 dbSNP
rs1415490728 955 dbSNP
rs979211256 959 dbSNP
rs1027698908 973 dbSNP
rs953169383 977 dbSNP
rs181886214 978 dbSNP
rs536405550 979 dbSNP
rs1203049873 982 dbSNP
rs923718972 983 dbSNP
rs1277627315 984 dbSNP
rs935090628 991 dbSNP
rs1464143867 1004 dbSNP
rs1273292162 1023 dbSNP
rs992421978 1027 dbSNP
rs917734755 1029 dbSNP
rs1214970598 1042 dbSNP
rs1216761685 1055 dbSNP
rs747256958 1060 dbSNP
rs1337601414 1065 dbSNP
rs1283003210 1070 dbSNP
rs986262060 1071 dbSNP
rs1327432988 1076 dbSNP
rs376462052 1078 dbSNP
rs1298162946 1084 dbSNP
rs911626457 1085 dbSNP
rs1262641996 1098 dbSNP
rs944217773 1104 dbSNP
rs947984311 1117 dbSNP
rs1044922002 1120 dbSNP
rs1254228469 1130 dbSNP
rs1462403552 1146 dbSNP
rs1374631980 1148 dbSNP
rs1190697820 1151 dbSNP
rs78285730 1152 dbSNP
rs1189900520 1162 dbSNP
rs1195100265 1170 dbSNP
rs1466805097 1176 dbSNP
rs1288492272 1177 dbSNP
rs576122827 1183 dbSNP
rs1340619801 1185 dbSNP
rs1053802022 1200 dbSNP
rs893773327 1203 dbSNP
rs1364745344 1209 dbSNP
rs1304515273 1216 dbSNP
rs771053215 1218 dbSNP
rs538787061 1233 dbSNP
rs1443368651 1236 dbSNP
rs1160860784 1237 dbSNP
rs1329456426 1239 dbSNP
rs1322946712 1249 dbSNP
rs948059885 1250 dbSNP
rs1391915628 1251 dbSNP
rs1398493654 1256 dbSNP
rs558892601 1261 dbSNP
rs576712658 1262 dbSNP
rs1325956645 1266 dbSNP
rs1003369255 1273 dbSNP
rs1014670569 1275 dbSNP
rs541433666 1277 dbSNP
rs879711964 1278 dbSNP
rs1181857175 1281 dbSNP
rs1438603735 1283 dbSNP
rs997597612 1285 dbSNP
rs897749667 1288 dbSNP
rs1030519234 1293 dbSNP
rs889265373 1299 dbSNP
rs1341975610 1304 dbSNP
rs749150112 1308 dbSNP
rs1027341367 1309 dbSNP
rs113744370 1309 dbSNP
rs541714797 1309 dbSNP
rs1274368077 1313 dbSNP
rs143736099 1327 dbSNP
rs1018740535 1333 dbSNP
rs965785092 1334 dbSNP
rs1309465809 1337 dbSNP
rs976922498 1357 dbSNP
rs77757597 1361 dbSNP
rs1375892960 1369 dbSNP
rs935612149 1385 dbSNP
rs186259720 1393 dbSNP
rs1412437050 1396 dbSNP
rs1273880210 1410 dbSNP
rs368825459 1418 dbSNP
rs532231770 1419 dbSNP
rs1220010189 1421 dbSNP
rs1409119125 1423 dbSNP
rs1180694873 1424 dbSNP
rs1246579473 1426 dbSNP
rs1483001339 1429 dbSNP
rs1030646030 1439 dbSNP
rs1454613448 1440 dbSNP
rs956687206 1443 dbSNP
rs760819012 1450 dbSNP
rs771138209 1451 dbSNP
rs1481178441 1452 dbSNP
rs1179275488 1460 dbSNP
rs1409360988 1464 dbSNP
rs969161554 1469 dbSNP
rs552329629 1471 dbSNP
rs1472047153 1481 dbSNP
rs1278110161 1484 dbSNP
rs1165087845 1487 dbSNP
rs1419378803 1488 dbSNP
rs1224537035 1494 dbSNP
rs1286509307 1497 dbSNP
rs948082553 1499 dbSNP
rs1322824895 1504 dbSNP
rs1355971376 1516 dbSNP
rs776748719 1518 dbSNP
rs928054789 1523 dbSNP
rs1358351896 1538 dbSNP
rs939403833 1539 dbSNP
rs1402050573 1559 dbSNP
rs559422094 1564 dbSNP
rs528041055 1568 dbSNP
rs1295507594 1580 dbSNP
rs548177757 1590 dbSNP
rs77560413 1593 dbSNP
rs1036166588 1599 dbSNP
rs941942250 1607 dbSNP
rs897629225 1612 dbSNP
rs536594099 1622 dbSNP
rs1183978013 1626 dbSNP
rs994662646 1627 dbSNP
rs919236504 1630 dbSNP
rs1237231977 1635 dbSNP
rs933419893 1637 dbSNP
rs1228011508 1641 dbSNP
rs75151836 1663 dbSNP
rs889031831 1664 dbSNP
rs4279857 1666 dbSNP
rs1208114452 1668 dbSNP
rs868080194 1681 dbSNP
rs148113978 1685 dbSNP
rs569946876 1688 dbSNP
rs1226526537 1689 dbSNP
rs1378217610 1692 dbSNP
rs1007273352 1696 dbSNP
rs1432481643 1698 dbSNP
rs906041522 1704 dbSNP
rs1463580352 1709 dbSNP
rs115575628 1723 dbSNP
rs1007764318 1727 dbSNP
rs1461455474 1755 dbSNP
rs199564348 1761 dbSNP
rs753882343 1761 dbSNP
rs200549142 1762 dbSNP
rs201358351 1763 dbSNP
rs1043243710 1765 dbSNP
rs558750002 1766 dbSNP
rs999102320 1774 dbSNP
rs957119977 1778 dbSNP
rs1031096297 1787 dbSNP
rs1451568206 1789 dbSNP
rs956374173 1804 dbSNP
rs1188156896 1805 dbSNP
rs34918838 1808 dbSNP
rs1482560375 1809 dbSNP
rs1469020870 1814 dbSNP
rs1188220322 1816 dbSNP
rs989654170 1817 dbSNP
rs1013298318 1820 dbSNP
rs867532193 1825 dbSNP
rs915517316 1828 dbSNP
rs969626704 1846 dbSNP
rs1216037374 1848 dbSNP
rs566176810 1849 dbSNP
rs1296490915 1850 dbSNP
rs969109349 1855 dbSNP
rs1372601726 1868 dbSNP
rs1471534751 1885 dbSNP
rs1291239114 1893 dbSNP
rs927938999 1896 dbSNP
rs1349739489 1897 dbSNP
rs569540795 1898 dbSNP
rs1432073855 1899 dbSNP
rs1168246514 1901 dbSNP
rs1162098049 1922 dbSNP
rs1420203646 1931 dbSNP
rs763394321 1934 dbSNP
rs866508103 1938 dbSNP
rs1269590255 1942 dbSNP
rs1189511547 1943 dbSNP
rs534665822 1957 dbSNP
rs537063959 1961 dbSNP
rs1481989231 1965 dbSNP
rs1369723429 1978 dbSNP
rs1415108562 1979 dbSNP
rs1298561291 1993 dbSNP
rs1218067215 2007 dbSNP
rs556665661 2009 dbSNP
rs971983007 2024 dbSNP
rs116045064 2029 dbSNP
rs1299307577 2034 dbSNP
rs141275871 2041 dbSNP
rs1307761239 2043 dbSNP
rs1435608816 2051 dbSNP
rs1051757578 2053 dbSNP
rs1432735688 2057 dbSNP
rs1408802836 2062 dbSNP
rs543775102 2066 dbSNP
rs1445961078 2071 dbSNP
rs943416179 2080 dbSNP
rs1250839260 2084 dbSNP
rs755547930 2086 dbSNP
rs1211249011 2088 dbSNP
rs1043273525 2097 dbSNP
rs1484035975 2100 dbSNP
rs1040077816 2102 dbSNP
rs1208978343 2103 dbSNP
rs904658328 2105 dbSNP
rs999530035 2113 dbSNP
rs1283650825 2117 dbSNP
rs1289660532 2123 dbSNP
rs1230801110 2128 dbSNP
rs1053332705 2133 dbSNP
rs1288124592 2135 dbSNP
rs1396918821 2136 dbSNP
rs896050608 2139 dbSNP
rs1216824855 2143 dbSNP
rs145001863 2144 dbSNP
rs1024580298 2150 dbSNP
rs749132678 2154 dbSNP
rs1161410869 2156 dbSNP
rs1031870560 2157 dbSNP
rs1001881378 2161 dbSNP
rs1411064927 2163 dbSNP
rs957140008 2168 dbSNP
rs1011492980 2170 dbSNP
rs1211980182 2171 dbSNP
rs576900664 2173 dbSNP
rs963203816 2178 dbSNP
rs1485965056 2180 dbSNP
rs972400403 2181 dbSNP
rs969625569 2188 dbSNP
rs1026263311 2190 dbSNP
rs1246161388 2193 dbSNP
rs954607382 2209 dbSNP
rs980965968 2210 dbSNP
rs1311000047 2211 dbSNP
rs928200775 2225 dbSNP
rs778744678 2241 dbSNP
rs910542754 2242 dbSNP
rs1455761632 2246 dbSNP
rs747924724 2248 dbSNP
rs201729561 2253 dbSNP
rs1186611260 2259 dbSNP
rs1165608176 2263 dbSNP
rs75688200 2271 dbSNP
rs1366525937 2273 dbSNP
rs978843091 2281 dbSNP
rs1428754373 2287 dbSNP
rs1249442490 2293 dbSNP
rs1435139529 2304 dbSNP
rs1186266473 2331 dbSNP
rs559143869 2332 dbSNP
rs1464103580 2337 dbSNP
rs1253047873 2340 dbSNP
rs1211011558 2351 dbSNP
rs1359031048 2360 dbSNP
rs1264053649 2365 dbSNP
rs919377461 2376 dbSNP
rs528191857 2378 dbSNP
rs934881488 2382 dbSNP
rs61815043 2395 dbSNP
rs1412968753 2396 dbSNP
rs985039668 2397 dbSNP
rs541456579 2400 dbSNP
rs545579765 2401 dbSNP
rs1388482964 2402 dbSNP
rs1437290867 2404 dbSNP
rs950292334 2414 dbSNP
rs1365048569 2421 dbSNP
rs1391782286 2430 dbSNP
rs1235542225 2432 dbSNP
rs1448480957 2442 dbSNP
rs943288482 2443 dbSNP
rs1306071318 2449 dbSNP
rs116080852 2451 dbSNP
rs904844745 2460 dbSNP
rs1001912772 2462 dbSNP
rs1453847794 2466 dbSNP
rs1015981872 2474 dbSNP
rs898900855 2481 dbSNP
rs993382645 2498 dbSNP
rs1483608246 2503 dbSNP
rs1026548546 2504 dbSNP
rs1226489020 2506 dbSNP
rs954639442 2507 dbSNP
rs987355367 2510 dbSNP
rs1017634195 2519 dbSNP
rs1247389939 2521 dbSNP
rs1329408472 2521 dbSNP
rs1454640780 2528 dbSNP
rs934351745 2532 dbSNP
rs964666647 2534 dbSNP
rs1305901805 2543 dbSNP
rs979261408 2556 dbSNP
rs747119669 2573 dbSNP
rs926099989 2581 dbSNP
rs934725268 2582 dbSNP
rs1172222352 2589 dbSNP
rs1385877232 2593 dbSNP
rs552791675 2598 dbSNP
rs1199387204 2600 dbSNP
rs1011294834 2607 dbSNP
rs1254452960 2614 dbSNP
rs1203377203 2623 dbSNP
rs373487920 2632 dbSNP
rs1196801971 2637 dbSNP
rs530312205 2653 dbSNP
rs1022903338 2658 dbSNP
rs1279678747 2659 dbSNP
rs1202394396 2660 dbSNP
rs1343011187 2661 dbSNP
rs905392786 2668 dbSNP
rs989025031 2678 dbSNP
rs1002315087 2691 dbSNP
rs776799568 2694 dbSNP
rs917389375 2697 dbSNP
rs189071790 2699 dbSNP
rs950321760 2706 dbSNP
rs1044586613 2721 dbSNP
rs867371455 2725 dbSNP
rs972478124 2726 dbSNP
rs570032866 2728 dbSNP
rs904877299 2737 dbSNP
rs78603860 2739 dbSNP
rs1458237415 2748 dbSNP
rs1037770066 2754 dbSNP
rs1414763913 2758 dbSNP
rs552744844 2760 dbSNP
rs181296362 2768 dbSNP
rs535162655 2782 dbSNP
rs1226091259 2785 dbSNP
rs1238381409 2786 dbSNP
rs533608024 2796 dbSNP
rs984871841 2813 dbSNP
rs1026160516 2820 dbSNP
rs1440860269 2830 dbSNP
rs537635254 2843 dbSNP
rs890267250 2848 dbSNP
rs1209372932 2853 dbSNP
rs1331308281 2855 dbSNP
rs1266232163 2860 dbSNP
rs1227675677 2861 dbSNP
rs377550837 2862 dbSNP
rs1285684378 2871 dbSNP
rs537466004 2872 dbSNP
rs1468908652 2873 dbSNP
rs1215487831 2880 dbSNP
rs1320661392 2886 dbSNP
rs186328207 2892 dbSNP
rs975908849 2893 dbSNP
rs1182207956 2897 dbSNP
rs1364638666 2899 dbSNP
rs577217973 2901 dbSNP
rs533950472 2915 dbSNP
rs1400615605 2921 dbSNP
rs964622404 2925 dbSNP
rs1000226657 2928 dbSNP
rs1165323797 2929 dbSNP
rs923224464 2934 dbSNP
rs934558457 2940 dbSNP
rs1033415823 2946 dbSNP
rs572713416 2974 dbSNP
rs989278625 2977 dbSNP
rs545631118 2978 dbSNP
rs971504772 2988 dbSNP
rs1215006253 2990 dbSNP
rs1322208004 3005 dbSNP
rs980232537 3006 dbSNP
rs1226346044 3008 dbSNP
rs1295829019 3012 dbSNP
rs1297967014 3021 dbSNP
rs1389158757 3047 dbSNP
rs1044165865 3050 dbSNP
rs927587157 3053 dbSNP
rs1386606573 3060 dbSNP
rs764697805 3062 dbSNP
rs941588328 3066 dbSNP
rs1329941816 3086 dbSNP
rs1037398350 3095 dbSNP
rs774918526 3096 dbSNP
rs929089302 3098 dbSNP
rs1404018727 3109 dbSNP
rs1002329817 3124 dbSNP
rs190830483 3125 dbSNP
rs1287244038 3127 dbSNP
rs1334928712 3131 dbSNP
rs77948961 3137 dbSNP
rs1185931323 3144 dbSNP
rs1008768384 3148 dbSNP
rs1263642676 3156 dbSNP
rs1488772229 3166 dbSNP
rs1248446291 3172 dbSNP
rs34494079 3180 dbSNP
rs1355515421 3185 dbSNP
rs1038868812 3186 dbSNP
rs1219282018 3191 dbSNP
rs896775457 3198 dbSNP
rs762247452 3201 dbSNP
rs1000492603 3202 dbSNP
rs1339587193 3204 dbSNP
rs993749582 3211 dbSNP
rs1219247581 3212 dbSNP
rs541578073 3233 dbSNP
rs541939636 3238 dbSNP
rs561323144 3247 dbSNP
rs1277158212 3248 dbSNP
rs956197904 3253 dbSNP
rs1006604129 3271 dbSNP
rs1308969814 3282 dbSNP
rs761598359 3286 dbSNP
rs750006279 3292 dbSNP
rs1010330440 3299 dbSNP
rs1024380456 3301 dbSNP
rs1367288538 3305 dbSNP
rs971452534 3306 dbSNP
rs1427323229 3313 dbSNP
rs1457829492 3319 dbSNP
rs980261667 3321 dbSNP
rs1252312253 3322 dbSNP
rs1372798259 3325 dbSNP
rs927451616 3330 dbSNP
rs35851029 3341 dbSNP
rs923088397 3347 dbSNP
rs530395377 3351 dbSNP
rs755673579 3355 dbSNP
rs142279758 3357 dbSNP
rs765738749 3359 dbSNP
rs1298496228 3361 dbSNP
rs974704594 3366 dbSNP
rs1397309809 3370 dbSNP
rs878898801 3373 dbSNP
rs36037469 3374 dbSNP
rs920276525 3380 dbSNP
rs914446158 3381 dbSNP
rs561669749 3383 dbSNP
rs563595070 3386 dbSNP
rs1349014957 3393 dbSNP
rs928930615 3396 dbSNP
rs532716569 3397 dbSNP
rs1228073037 3417 dbSNP
rs1360993890 3424 dbSNP
rs1047419674 3443 dbSNP
rs552488753 3454 dbSNP
rs776735781 3467 dbSNP
rs944427068 3477 dbSNP
rs1038899018 3487 dbSNP
rs1471509752 3490 dbSNP
rs1204135069 3504 dbSNP
rs1223963387 3529 dbSNP
rs1249528064 3540 dbSNP
rs1056585301 3544 dbSNP
rs1484005878 3549 dbSNP
rs1253741292 3557 dbSNP
rs12036080 3566 dbSNP
rs1183732573 3570 dbSNP
rs1329218939 3573 dbSNP
rs1254162227 3574 dbSNP
rs1230746202 3583 dbSNP
rs753381329 3583 dbSNP
rs1000122185 3586 dbSNP
rs528556518 3590 dbSNP
rs994046101 3600 dbSNP
rs1452085699 3612 dbSNP
rs1194529557 3629 dbSNP
rs1054748156 3630 dbSNP
rs754966239 3631 dbSNP
rs1161343243 3633 dbSNP
rs1047986472 3635 dbSNP
rs1363041191 3641 dbSNP
rs56246017 3644 dbSNP
rs1006263781 3649 dbSNP
rs72741396 3649 dbSNP
rs907324121 3650 dbSNP
rs570591442 3670 dbSNP
rs964820468 3670 dbSNP
rs1001542942 3671 dbSNP
rs1034496102 3680 dbSNP
rs955911365 3682 dbSNP
rs989017222 3685 dbSNP
rs1260512078 3689 dbSNP
rs1245911829 3703 dbSNP
rs879740912 3710 dbSNP
rs1375731863 3711 dbSNP
rs1313277981 3719 dbSNP
rs1467247865 3726 dbSNP
rs963165011 3732 dbSNP
rs138296069 3734 dbSNP
rs758146050 3735 dbSNP
rs1380461321 3743 dbSNP
rs1384079901 3755 dbSNP
rs974359531 3759 dbSNP
rs377378366 3765 dbSNP
rs1294022832 3775 dbSNP
rs1459307782 3792 dbSNP
rs1300648511 3793 dbSNP
rs1162592700 3823 dbSNP
rs1026349643 3831 dbSNP
rs1391519661 3835 dbSNP
rs1400891776 3836 dbSNP
rs1445787915 3840 dbSNP
rs1261712532 3861 dbSNP
rs1210956047 3864 dbSNP
rs914497743 3867 dbSNP
rs938807917 3871 dbSNP
rs1289980321 3872 dbSNP
rs951657726 3877 dbSNP
rs1343055018 3878 dbSNP
rs1363513257 3882 dbSNP
rs1425663638 3882 dbSNP
rs374801550 3882 dbSNP
rs568062478 3882 dbSNP
rs763087244 3882 dbSNP
rs969036849 3882 dbSNP
rs77525039 3883 dbSNP
rs182694371 3886 dbSNP
rs539761547 3887 dbSNP
rs1165779169 3888 dbSNP
rs926946688 3888 dbSNP
rs184985494 3889 dbSNP
rs149614308 3890 dbSNP
rs1212514620 3892 dbSNP
rs1254421476 3898 dbSNP
rs1435382736 3898 dbSNP
rs200767812 3899 dbSNP
rs1209393795 3901 dbSNP
rs1250486122 3909 dbSNP
rs918300677 3910 dbSNP
rs1194263590 3916 dbSNP
rs929496593 3917 dbSNP
rs1256616762 3935 dbSNP
rs1048360878 3937 dbSNP
rs1343496618 3938 dbSNP
rs888071871 3945 dbSNP
rs1410270613 3946 dbSNP
rs191019928 3950 dbSNP
rs537728508 3957 dbSNP
rs935869269 3959 dbSNP
rs1054294265 3962 dbSNP
rs1396075856 3965 dbSNP
rs1408958445 3968 dbSNP
rs891732141 3971 dbSNP
rs1402334481 3973 dbSNP
rs78783521 3984 dbSNP
rs575000660 3988 dbSNP
rs1173548043 3990 dbSNP
rs1199320220 4005 dbSNP
rs769925254 4012 dbSNP
rs1254386465 4019 dbSNP
rs1179957281 4037 dbSNP
rs1437424345 4038 dbSNP
rs543803610 4043 dbSNP
rs1202194460 4045 dbSNP
rs997489354 4052 dbSNP
rs1030429148 4063 dbSNP
rs1358176889 4069 dbSNP
rs10494893 4077 dbSNP
rs1001574000 4095 dbSNP
rs749377635 4097 dbSNP
rs1021868916 4126 dbSNP
rs1434278164 4130 dbSNP
rs1034814089 4131 dbSNP
rs1449914114 4133 dbSNP
rs1404677180 4139 dbSNP
rs11120148 4140 dbSNP
rs1458181820 4144 dbSNP
rs774968072 4146 dbSNP
rs1157128467 4149 dbSNP
rs779957583 4151 dbSNP
rs1469833513 4152 dbSNP
rs762300538 4158 dbSNP
rs1299499923 4159 dbSNP
rs959710041 4170 dbSNP
rs987028260 4179 dbSNP
rs1018624797 4190 dbSNP
rs992416663 4192 dbSNP
rs1466145455 4193 dbSNP
rs965671026 4197 dbSNP
rs974400107 4209 dbSNP
rs144314283 4211 dbSNP
rs1270076796 4218 dbSNP
rs767946985 4222 dbSNP
rs983669090 4228 dbSNP
rs75460793 4235 dbSNP
rs942154001 4239 dbSNP
rs1247753317 4243 dbSNP
rs1489689994 4245 dbSNP
rs990417107 4248 dbSNP
rs913034680 4253 dbSNP
rs377711168 4255 dbSNP
rs199607559 4258 dbSNP
rs371388995 4258 dbSNP
rs149458015 4259 dbSNP
rs71154803 4259 dbSNP
rs945982739 4259 dbSNP
rs66822120 4260 dbSNP
rs1045583025 4263 dbSNP
rs1316834387 4265 dbSNP
rs1400559629 4269 dbSNP
rs1165761624 4270 dbSNP
rs1472708114 4270 dbSNP
rs1442958315 4272 dbSNP
rs386369451 4273 dbSNP
rs1384689837 4274 dbSNP
rs1319500542 4277 dbSNP
rs772932507 4283 dbSNP
rs937376193 4288 dbSNP
rs1055796159 4291 dbSNP
rs142447284 4297 dbSNP
rs528652091 4297 dbSNP
rs933311332 4303 dbSNP
rs1456193607 4304 dbSNP
rs368216308 4304 dbSNP
rs199809882 4305 dbSNP
rs1165585408 4306 dbSNP
rs1214941826 4308 dbSNP
rs898596961 4318 dbSNP
rs1452012825 4327 dbSNP
rs1351502646 4339 dbSNP
rs12083861 4340 dbSNP
rs562115965 4342 dbSNP
rs12079709 4343 dbSNP
rs1358204276 4348 dbSNP
rs1297717895 4356 dbSNP
rs887234811 4366 dbSNP
rs550984651 4373 dbSNP
rs1019914413 4380 dbSNP
rs904372062 4385 dbSNP
rs867459174 4386 dbSNP
rs996270068 4388 dbSNP
rs1430617317 4390 dbSNP
rs1350857479 4394 dbSNP
rs1001292925 4401 dbSNP
rs1410660461 4402 dbSNP
rs1422989264 4403 dbSNP
rs1365249777 4418 dbSNP
rs533507033 4420 dbSNP
rs957359609 4421 dbSNP
rs1417432943 4426 dbSNP
rs959947871 4427 dbSNP
rs754453547 4431 dbSNP
rs1270786806 4442 dbSNP
rs1227818802 4443 dbSNP
rs1196947534 4451 dbSNP
rs765186612 4460 dbSNP
rs570891871 4461 dbSNP
rs981232838 4466 dbSNP
rs1219904583 4467 dbSNP
rs928594579 4468 dbSNP
rs937240356 4469 dbSNP
rs1214535825 4471 dbSNP
rs1483549989 4478 dbSNP
rs1368845559 4481 dbSNP
rs1183911243 4484 dbSNP
rs984297080 4488 dbSNP
rs909605062 4495 dbSNP
rs12087244 4501 dbSNP
rs919915248 4503 dbSNP
rs1403521529 4510 dbSNP
rs1463675862 4512 dbSNP
rs1163890935 4537 dbSNP
rs931392643 4543 dbSNP
rs183196967 4545 dbSNP
rs1431433568 4560 dbSNP
rs1174178523 4571 dbSNP
rs752580171 4580 dbSNP
rs546787716 4584 dbSNP
rs1060286 4585 dbSNP
rs1252251197 4598 dbSNP
rs147358194 4602 dbSNP
rs1008441266 4609 dbSNP
rs555190455 4616 dbSNP
rs1051799705 4617 dbSNP
rs891771421 4639 dbSNP
rs1041217221 4640 dbSNP
rs867876131 4643 dbSNP
rs60785875 4649 dbSNP
rs1222197457 4654 dbSNP
rs1227113726 4657 dbSNP
rs1323300051 4658 dbSNP
rs760241438 4660 dbSNP
rs997078515 4669 dbSNP
rs1371388081 4671 dbSNP
rs1297810251 4672 dbSNP
rs187528909 4675 dbSNP
rs904580667 4677 dbSNP
rs1334676294 4682 dbSNP
rs557309796 4696 dbSNP
rs777367116 4702 dbSNP
rs1160938105 4711 dbSNP
rs1417065163 4715 dbSNP
rs1343342175 4717 dbSNP
rs1182048791 4726 dbSNP
rs1207686657 4726 dbSNP
rs1029093027 4727 dbSNP
rs577539094 4729 dbSNP
rs75079916 4732 dbSNP
rs1011747787 4739 dbSNP
rs1060287 4741 dbSNP
rs1025538748 4746 dbSNP
rs142733751 4747 dbSNP
rs549562092 4748 dbSNP
rs1471484659 4753 dbSNP
rs1315503066 4754 dbSNP
rs981263755 4771 dbSNP
rs1005185404 4774 dbSNP
rs1385119546 4779 dbSNP
rs1334744253 4784 dbSNP
rs1451832910 4789 dbSNP
rs749367877 4795 dbSNP
rs1385649945 4797 dbSNP
rs191886349 4803 dbSNP
rs535058802 4805 dbSNP
rs565824559 4806 dbSNP
rs868259737 4806 dbSNP
rs1165068511 4807 dbSNP
rs145648377 4807 dbSNP
rs1382857728 4810 dbSNP
rs569603794 4816 dbSNP
rs928457791 4827 dbSNP
rs562308999 4832 dbSNP
rs958634626 4835 dbSNP
rs1263131025 4837 dbSNP
rs1207378949 4839 dbSNP
rs1485125464 4849 dbSNP
rs1565 4855 dbSNP
rs1223546571 4857 dbSNP
rs1361781142 4857 dbSNP
rs1313030842 4870 dbSNP
rs1245419741 4879 dbSNP
rs544742944 4881 dbSNP
rs974941451 4882 dbSNP
rs1380404285 4883 dbSNP
rs922081235 4884 dbSNP
rs931364684 4902 dbSNP
rs1303461141 4903 dbSNP
rs1426175876 4904 dbSNP
rs1363392156 4915 dbSNP
rs1560 4916 dbSNP
rs748609059 4920 dbSNP
rs1335023833 4924 dbSNP
rs772700196 4936 dbSNP
rs1427224003 4942 dbSNP
rs1261481371 4943 dbSNP
rs944092016 4949 dbSNP
rs1041249268 4952 dbSNP
rs1200527325 4955 dbSNP
rs773504906 4957 dbSNP
rs1490940946 4975 dbSNP
rs899975966 4977 dbSNP
rs1450873399 4979 dbSNP
rs932897915 4987 dbSNP
rs988146499 4987 dbSNP
rs1054005556 4992 dbSNP
rs1340175386 4994 dbSNP
rs894039588 5013 dbSNP
rs1225157146 5017 dbSNP
rs1011280013 5034 dbSNP
rs946043807 5037 dbSNP
rs533323322 5038 dbSNP
rs546685459 5040 dbSNP
rs1302202185 5041 dbSNP
rs926075805 5069 dbSNP
rs566757777 5070 dbSNP
rs937415532 5070 dbSNP
rs1002548906 5083 dbSNP
rs1035491072 5085 dbSNP
rs1177740105 5092 dbSNP
rs1295842166 5097 dbSNP
rs1341103913 5098 dbSNP
rs1267146516 5108 dbSNP
rs761077569 5120 dbSNP
rs1438541251 5121 dbSNP
rs1280228649 5122 dbSNP
rs183069613 5123 dbSNP
rs1440228413 5136 dbSNP
rs1208780429 5142 dbSNP
rs958531746 5148 dbSNP
rs529215249 5151 dbSNP
rs1338819525 5155 dbSNP
rs1263723280 5156 dbSNP
rs1225248001 5157 dbSNP
rs991724188 5159 dbSNP
rs1282354535 5160 dbSNP
rs1239326883 5164 dbSNP
rs1466190474 5177 dbSNP
rs770529561 5180 dbSNP
rs1326432581 5184 dbSNP
rs952721849 5199 dbSNP
rs982811836 5200 dbSNP
rs1471217937 5210 dbSNP
rs781236593 5213 dbSNP
rs886991067 5215 dbSNP
rs1005670442 5218 dbSNP
rs548754678 5245 dbSNP
rs944121185 5247 dbSNP
rs559206876 5252 dbSNP
rs1437369705 5265 dbSNP
rs537672535 5279 dbSNP
rs1427475473 5284 dbSNP
rs1205518733 5290 dbSNP
rs557398119 5298 dbSNP
rs1262298636 5308 dbSNP
rs1205562918 5311 dbSNP
rs372201337 5321 dbSNP
rs571265702 5322 dbSNP
rs1382920816 5326 dbSNP
rs1316442771 5329 dbSNP
rs1054359302 5331 dbSNP
rs1029394459 5335 dbSNP
rs1334077101 5342 dbSNP
rs1401690632 5346 dbSNP
rs533736039 5351 dbSNP
rs1390092811 5364 dbSNP
rs954869593 5371 dbSNP
rs1157071185 5375 dbSNP
rs1437895774 5376 dbSNP
rs1439274448 5389 dbSNP
rs112930070 5399 dbSNP
rs1487271012 5400 dbSNP
rs746048111 5401 dbSNP
rs1364939239 5415 dbSNP
rs1236903448 5421 dbSNP
rs573471365 5422 dbSNP
rs1216374819 5429 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugagucgccggcAAAGGGGUu 5'
                       |||||||| 
Target 5' ----------uuaUUUCCCCAc 3'
 		1 - 12
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000367080.3 | 3UTR | UUAUUUCCCCACUCUCACCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BLCA 0.552 0.02 0.543 0.02 15 Click to see details
PRAD 0.336 0.02 0.350 0.02 35 Click to see details
KICH 0.371 0.04 0.332 0.06 24 Click to see details
LUAD -0.478 0.06 -0.476 0.06 12 Click to see details
LUSC -0.286 0.07 -0.265 0.08 29 Click to see details
PAAD -0.974 0.07 -1.000 0.5 3 Click to see details
ESCA 0.409 0.11 0.436 0.09 11 Click to see details
KIRP 0.214 0.13 0.106 0.29 30 Click to see details
PCPG -0.916 0.13 -1.000 0.5 3 Click to see details
STAD 0.157 0.2 0.154 0.21 30 Click to see details
LIHC 0.1 0.26 -0.027 0.43 45 Click to see details
THCA 0.056 0.34 -0.002 0.49 58 Click to see details
BRCA 0.04 0.38 0.103 0.22 58 Click to see details
UCEC 0.074 0.39 0.061 0.4 18 Click to see details
CESC 0.329 0.39 0.500 0.33 3 Click to see details
COAD 0.312 0.4 -0.500 0.33 3 Click to see details
CHOL -0.13 0.4 -0.086 0.44 6 Click to see details
HNSC 0.005 0.49 -0.015 0.46 39 Click to see details
KIRC 0.003 0.49 -0.042 0.38 53 Click to see details
KIRC 0.003 0.49 -0.042 0.38 53 Click to see details
KIRC 0.003 0.49 -0.042 0.38 53 Click to see details
96 hsa-miR-2110 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT035757 BRD4 bromodomain containing 4 1 1
MIRT035758 NCOR2 nuclear receptor corepressor 2 1 1
MIRT035759 FASN fatty acid synthase 1 1
MIRT035760 C10orf118 coiled-coil domain containing 186 1 1
MIRT055403 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT066205 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT079365 CCDC137 coiled-coil domain containing 137 2 2
MIRT081180 MIDN midnolin 2 4
MIRT082397 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 4
MIRT089000 BCL11A B-cell CLL/lymphoma 11A 2 2
MIRT133706 SKI SKI proto-oncogene 2 4
MIRT160053 TET3 tet methylcytosine dioxygenase 3 2 4
MIRT180853 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT263243 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT285532 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT317152 E2F3 E2F transcription factor 3 2 4
MIRT321166 EIF4H eukaryotic translation initiation factor 4H 2 2
MIRT441482 NCEH1 neutral cholesterol ester hydrolase 1 2 2
MIRT443884 CNKSR3 CNKSR family member 3 2 2
MIRT445877 WBP1L WW domain binding protein 1 like 2 2
MIRT446195 GTPBP4 GTP binding protein 4 2 2
MIRT449308 MRO maestro 2 2
MIRT450301 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT450512 EMX1 empty spiracles homeobox 1 2 2
MIRT451534 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451820 ALDH3B1 aldehyde dehydrogenase 3 family member B1 2 2
MIRT452239 TRAM1 translocation associated membrane protein 1 2 2
MIRT454207 HLA-A major histocompatibility complex, class I, A 2 2
MIRT455447 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT456496 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2 2
MIRT457656 SERINC1 serine incorporator 1 2 2
MIRT459819 TPP1 tripeptidyl peptidase 1 2 2
MIRT460556 FEM1A fem-1 homolog A 2 2
MIRT462561 STS steroid sulfatase 2 2
MIRT462986 ZNF740 zinc finger protein 740 2 2
MIRT464671 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465432 TP53 tumor protein p53 2 2
MIRT465934 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466015 TMEM189 transmembrane protein 189 2 2
MIRT468122 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT469652 RAC1 Rac family small GTPase 1 2 2
MIRT469980 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT473531 MAX MYC associated factor X 2 2
MIRT473596 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT473652 MARCKSL1 MARCKS like 1 2 2
MIRT474219 LCOR ligand dependent nuclear receptor corepressor 2 4
MIRT474771 KIAA0895L KIAA0895 like 2 2
MIRT479312 VPS72 vacuolar protein sorting 72 homolog 2 2
MIRT481121 AZIN1 antizyme inhibitor 1 2 4
MIRT481682 AR androgen receptor 2 2
MIRT482381 AEN apoptosis enhancing nuclease 2 2
MIRT483833 UNC5B unc-5 netrin receptor B 2 4
MIRT484693 RNF11 ring finger protein 11 2 2
MIRT485238 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT488748 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT489147 MRPL12 mitochondrial ribosomal protein L12 2 4
MIRT489518 MRE11A MRE11 homolog, double strand break repair nuclease 2 8
MIRT498908 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT506426 NAGK N-acetylglucosamine kinase 2 6
MIRT506640 MAPK1 mitogen-activated protein kinase 1 2 4
MIRT507332 FAM168A family with sequence similarity 168 member A 2 2
MIRT513099 DYNAP dynactin associated protein 2 2
MIRT513514 YIPF4 Yip1 domain family member 4 2 6
MIRT521800 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT525078 FRK fyn related Src family tyrosine kinase 2 2
MIRT530927 SCIN scinderin 2 2
MIRT533498 TRIM71 tripartite motif containing 71 2 2
MIRT536787 HNRNPD heterogeneous nuclear ribonucleoprotein D 2 2
MIRT544554 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT552977 VAT1 vesicle amine transport 1 2 2
MIRT557358 HAND1 heart and neural crest derivatives expressed 1 2 2
MIRT560401 TMEM69 transmembrane protein 69 2 2
MIRT565498 SP1 Sp1 transcription factor 2 2
MIRT568962 CACNA1C calcium voltage-gated channel subunit alpha1 C 2 2
MIRT569031 IL21R interleukin 21 receptor 2 2
MIRT573224 TRIM21 tripartite motif containing 21 2 2
MIRT574312 ZNF703 zinc finger protein 703 2 2
MIRT620395 MYO1H myosin IH 2 2
MIRT620936 OSMR oncostatin M receptor 2 2
MIRT638166 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT647743 SAMD9L sterile alpha motif domain containing 9 like 2 2
MIRT649991 MSI1 musashi RNA binding protein 1 2 2
MIRT669203 CBX8 chromobox 8 2 2
MIRT684546 ZNF708 zinc finger protein 708 2 2
MIRT685837 ANGEL1 angel homolog 1 2 2
MIRT688547 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT693252 HBS1L HBS1 like translational GTPase 2 2
MIRT701970 MIER3 MIER family member 3 2 2
MIRT706385 MC2R melanocortin 2 receptor 2 2
MIRT707484 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT711882 INSIG2 insulin induced gene 2 2 2
MIRT716906 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT717638 HLX H2.0 like homeobox 2 2
MIRT719058 ZNF281 zinc finger protein 281 2 2
MIRT723754 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 2
MIRT725479 GPR26 G protein-coupled receptor 26 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-2110 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer tissue
hsa-miR-2110 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-mir-2110 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-2110 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-2110 Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-2110 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-2110 Vincristine 5978 approved sensitive cell line (W1)
hsa-mir-2110 Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-mir-2110 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-mir-2110 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-2110 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-mir-2110 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-2110 Cisplatin 5460033 NSC119875 approved resistant cell line (SGC-7901)
hsa-miR-2110 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-2110 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved resistant cell line
hsa-miR-2110 Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-2110 Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-2110 Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-2110 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-2110 Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-2110 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)
hsa-miR-2110 Cisplatin 5460033 NSC119875 approved resistant cell line (OVSAHO)

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