miRTarBase - #MIRT456665


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pre-miRNA Information
pre-miRNA hsa-mir-1247   
Genomic Coordinates chr14: 101560287 - 101560422
Synonyms MIRN1247, hsa-mir-1247, MIR1247
Description Homo sapiens miR-1247 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1247-3p
Sequence 74| CCCCGGGAACGUCGAGACUGGAGC |97
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs765946490 1 dbSNP
rs1167774642 3 dbSNP
rs369874810 4 dbSNP
rs1295169065 5 dbSNP
rs1368557653 7 dbSNP
rs375254504 10 dbSNP
rs1049152389 16 dbSNP
rs774601647 21 dbSNP
rs1317190334 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TIFA   
Synonyms T2BP, T6BP, TIFAA
Description TRAF interacting protein with forkhead associated domain
Transcript NM_052864   
Expression
Putative miRNA Targets on TIFA
3'UTR of TIFA
(miRNA target sites are highlighted)		 
>TIFA|NM_052864|3'UTR
   1 ACACAGAAAGTCTAAGAGGAGAAATATGATGGATGAAGAGCTCTGTAGATGCTGTATAGACACTAAATAAGAGTTGATTA
  81 GGGTAGTATATTATAGTCATCTGTTATGCTGTGAAATTTGGAATTCAGTATTATCATTTTGAAGTCTGTAAATTGTGTTA
 161 GTCATTAACTTAGTCACCTGTTGTATTCTGGATCTACACAAAATTATTTTAACTGCTCTTATTAATCTGTGAGGATTAAT
 241 ATACAAAAAGTATCCTTTGAGATGAAGTCGTGTTCTCAAAATAAGGTTATATTATTTTCTTTTTCTGCTTGATTTTCATC
 321 TTGTGTTTTGCTTTGTTTTTGTAAGGAACCATCTCTTGGTTTGGTCACATCAGTTCACAACAGCCATTTGTTTTCAAGGT
 401 CAAGGCTCCAGGCAGGTTGTTACTGGTGTTTGCAGCCTGTCAGTACTTGCAGTACTGGAATAGGTTCTAGGCTAGTGTCT
 481 GCGCGTCACTGTGGTTTTAGCATGGGAGGACTTATTTGAGAAATACTACCTTACTTTTCTATGATTTCTTTTTACAGAGT
 561 TATAGTGTGTTTACTCCTAAGATGACAGTTCTCTTTGTCTATATTCAGCATCTAAGACAAATATTTAAACATTTTAAAGA
 641 ACCACTGTGTTAAGTTTAGGATTATTTACTTACCAAATTAGAAGTTTGACTTTTATGTGTTATACACAATCTTAAAATTT
 721 CACGAATTCACCTTTTTAATAGTATCCATGTACATAATAAAATCAAAGTTTAATTAGCCATTTTCTTTGAATTTTTTTCT
 801 AAATAAGGGAAATAACTGTTCTTGGGCCACTTTACAGAGATAAATGTATGTGAATGTTTATGATAAACGCTTAAATATTT
 881 CTAAAATATTAACTTCAAAAAAGTCTTTTTCAGTTCTTAAATAAAAATTTATTTATTTAAGATACTTATTCGACTTATCT
 961 TAACTAAGGTAGCTATGAATGTTAAGTAGATGAGGTAACCATTCAGTTAAGTTAAATTGTAGCATTGCCAGGTAGTGAGG
1041 CTCACTGTACAATTTTCCAGGTAAATGAAATTTCCTGTAGTAAGAGGTCCGTATTTTTGTAACAGCCTTTTAAAAATGCT
1121 TTTGGGAACCCTCCAGCCTCTTACCAAAAGAGGCTTTAAACCTCATCTTGATTCAGACTGTCAGTCTATTCCTGGGCAGT
1201 AGTATGTGATGTCCAGCACCCTAACCCCGACTCCCCAGCCCTGGGACTATTCCAGTAGAGTGAAATATTTGTCCCTGTAC
1281 AAAGTGGCCTGAATGACTGTTGGAGTTCCTGTGTCTGGTTTTCCTGTTTATTCCCTGTGATGCCCAGAGTAATGGCCCAT
1361 CCAAAGATGTCCAGATGTCCATGTGCTAGTCTCCAGAACTTGTAACTGTGTTGTTATGTGGCAAAGGGGAATGAAGGCTG
1441 CAGATGGAAGTAAAATAGATTATGCTGGATTATCTGGGTGTGCCCAATTGATCACCGGATCCGTAAAAGTGGAAGAGAGG
1521 CAGATCAGGATGTCAGCGTGATGAGGTGTGAGACAGACTTGACTTGCTGTTGCTGGGAGGAAGGGGAGGTCATGAGCCAA
1601 GGAATGTGGACAGTCTCTTGAAGCTGGAAAGTGTGCATTGGACATCTGGAAGCCAGAAAAGACAAAGAAATATCCAGAAA
1681 GGAACAAAGTCTTGTGGACACCTTGATTTTGGTCCAGTGAGAATATGTTTGACTTGTTAACCTACAAAACTTTATGATGA
1761 TAAATTTGTGTTGGTCGTAAGCCACTAAATCACAGTAATTTGTTATAGCAGCAGATAGAAAACTAATATACTCCCTTTAA
1841 TATAAGGTTATCTACTATTGATTCTTTCTAGGATTTTAGCTTCTGGTCTGATGTGGGTTTACAGCCAGATCACCCGGCTT
1921 GAATTGCTTACAGTGTGTAGTCTCATGGTAAAGGCGTTCTATGAGTGAAGTGTATATACTTTAATGTGTGTATACTGTCA
2001 CATTTTGACTATTTTGGAAGACTTTCACCTCTGTTTCTTGTCTTTGAGGCTGATGAATGTGTTTCTAAGTTATAAATTTA
2081 ATATTAAGGGATTCATGTATTATTGTTATTGAATCCAAACAATGTGTTAAGTAATATTTAGGGCCAGAAAAATCTTGTAC
2161 AGAATAATGATTTCTCCTAATGTAAATCTTGGAAAGGGTTTTGTTCAACTTGAGAAATATTAAATTTTTTATTCTAAAAA
2241 AAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgaGGUCAGAGCUGCAAGGGCCCc 5'
             :||||||  |  ||||:||| 
Target 5' ctgTCAGTCT--A--TTCCTGGGc 3'
 1178 - 1197 145.00 -20.90
2 
miRNA  3' cgagGUCAGAGCUG-----CAAGGGCCCc 5'
              ||| ||:|||     ||| |:||| 
Target 5' gagaCAGACTTGACTTGCTGTTGCTGGGa 3'
 1550 - 1578 124.00 -20.10
3 
miRNA  3' cgaggucagagcUG-CAAGGGCCCc 5'
                      || ||||::||| 
Target 5' ataagggaaataACTGTTCTTGGGc 3'
 803 - 827 120.00 -13.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30188708 3 COSMIC
COSN30454618 58 COSMIC
COSN30523863 66 COSMIC
COSN1285427 128 COSMIC
COSN17957728 128 COSMIC
COSN15665650 129 COSMIC
COSN17503050 129 COSMIC
COSN1285426 131 COSMIC
COSN20100429 134 COSMIC
COSN9899336 452 COSMIC
COSN21835381 584 COSMIC
COSN20100428 685 COSMIC
COSN15662944 994 COSMIC
COSN5151300 1078 COSMIC
COSN21799052 1170 COSMIC
COSN30167957 1506 COSMIC
COSN9899335 1561 COSMIC
COSN15617675 1604 COSMIC
COSN16134179 1852 COSMIC
COSN23138850 2359 COSMIC
COSN5855230 2592 COSMIC
COSN24286435 2738 COSMIC
COSN26291110 3129 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1459205826 2 dbSNP
rs115579603 6 dbSNP
rs757637989 7 dbSNP
rs754320526 10 dbSNP
rs1186596230 14 dbSNP
rs543586258 15 dbSNP
rs370828737 22 dbSNP
rs1224182128 25 dbSNP
rs35118651 25 dbSNP
rs775595385 27 dbSNP
rs1038227328 30 dbSNP
rs756847721 32 dbSNP
rs1320705930 40 dbSNP
rs762154366 43 dbSNP
rs1030924120 48 dbSNP
rs576495457 49 dbSNP
rs774284380 50 dbSNP
rs757960458 53 dbSNP
rs773157188 54 dbSNP
rs999736134 58 dbSNP
rs1267190475 59 dbSNP
rs555071000 62 dbSNP
rs1485675376 67 dbSNP
rs1203566734 74 dbSNP
rs1258394250 83 dbSNP
rs1424519748 85 dbSNP
rs889436023 87 dbSNP
rs901022945 89 dbSNP
rs536649453 96 dbSNP
rs1160384066 101 dbSNP
rs1476652937 103 dbSNP
rs1006918628 105 dbSNP
rs1304268434 114 dbSNP
rs1402445510 121 dbSNP
rs199948541 128 dbSNP
rs201650588 129 dbSNP
rs5861096 130 dbSNP
rs2351487 131 dbSNP
rs143759875 132 dbSNP
rs368085116 132 dbSNP
rs5861095 133 dbSNP
rs747214596 133 dbSNP
rs774148133 133 dbSNP
rs1228874995 134 dbSNP
rs2351486 134 dbSNP
rs201531799 135 dbSNP
rs869113980 135 dbSNP
rs5861094 136 dbSNP
rs754292465 136 dbSNP
rs758589646 136 dbSNP
rs796739894 136 dbSNP
rs3080382 137 dbSNP
rs145580634 139 dbSNP
rs889903819 147 dbSNP
rs1048381703 159 dbSNP
rs1483697497 160 dbSNP
rs1441751994 161 dbSNP
rs1254074406 163 dbSNP
rs1197502659 165 dbSNP
rs1339777520 167 dbSNP
rs535203005 170 dbSNP
rs1257225694 171 dbSNP
rs1217000315 173 dbSNP
rs1337289242 174 dbSNP
rs1255415536 176 dbSNP
rs1293973131 176 dbSNP
rs1414317674 183 dbSNP
rs1445667493 185 dbSNP
rs1338782286 187 dbSNP
rs1385120232 188 dbSNP
rs1331393022 189 dbSNP
rs1484335444 190 dbSNP
rs113084810 191 dbSNP
rs1441573079 191 dbSNP
rs1183483415 199 dbSNP
rs1417753311 204 dbSNP
rs701758 213 dbSNP
rs1037299682 218 dbSNP
rs1433644314 220 dbSNP
rs1310560260 224 dbSNP
rs1371819530 231 dbSNP
rs1410393734 232 dbSNP
rs1297582820 237 dbSNP
rs938826539 241 dbSNP
rs1463710664 254 dbSNP
rs1419648011 258 dbSNP
rs1301630669 263 dbSNP
rs1042285228 267 dbSNP
rs770061263 270 dbSNP
rs928802114 272 dbSNP
rs980710613 279 dbSNP
rs1205929311 282 dbSNP
rs539318558 284 dbSNP
rs1366231285 286 dbSNP
rs71604933 287 dbSNP
rs571779303 290 dbSNP
rs990372860 297 dbSNP
rs958725280 299 dbSNP
rs1268426114 311 dbSNP
rs1183857631 312 dbSNP
rs1453447575 318 dbSNP
rs141101915 349 dbSNP
rs531779445 358 dbSNP
rs989112376 359 dbSNP
rs1169125067 363 dbSNP
rs746056585 365 dbSNP
rs781280496 383 dbSNP
rs1196590628 390 dbSNP
rs1469991089 399 dbSNP
rs567044943 400 dbSNP
rs957701933 402 dbSNP
rs548622471 412 dbSNP
rs527300743 414 dbSNP
rs1367603324 420 dbSNP
rs1227974843 422 dbSNP
rs1272298062 432 dbSNP
rs978014434 434 dbSNP
rs1224368701 436 dbSNP
rs1281380883 439 dbSNP
rs559709785 442 dbSNP
rs545001555 443 dbSNP
rs1019437706 446 dbSNP
rs1376872428 447 dbSNP
rs1449621546 449 dbSNP
rs1006720667 450 dbSNP
rs1416704439 451 dbSNP
rs889831397 453 dbSNP
rs752017192 459 dbSNP
rs1165444283 465 dbSNP
rs1025694312 467 dbSNP
rs1393613353 469 dbSNP
rs1027035717 471 dbSNP
rs955361 472 dbSNP
rs1391115074 476 dbSNP
rs183470156 482 dbSNP
rs1269696260 483 dbSNP
rs556035008 484 dbSNP
rs562605995 485 dbSNP
rs1294495225 490 dbSNP
rs1037464192 492 dbSNP
rs544417614 501 dbSNP
rs1404432867 510 dbSNP
rs777270858 515 dbSNP
rs938938051 541 dbSNP
rs564329210 549 dbSNP
rs1214577576 556 dbSNP
rs778273307 557 dbSNP
rs1239971500 559 dbSNP
rs117117957 575 dbSNP
rs889486346 579 dbSNP
rs1159847551 582 dbSNP
rs1470464920 583 dbSNP
rs1417162220 588 dbSNP
rs1474147436 589 dbSNP
rs1029275454 591 dbSNP
rs1412376553 603 dbSNP
rs997826304 626 dbSNP
rs1379691390 642 dbSNP
rs1176706140 643 dbSNP
rs1313485201 645 dbSNP
rs1292363027 646 dbSNP
rs902265145 647 dbSNP
rs916301740 648 dbSNP
rs1042116902 653 dbSNP
rs1290629044 657 dbSNP
rs989246145 676 dbSNP
rs1450126372 679 dbSNP
rs1281777169 680 dbSNP
rs1443781083 681 dbSNP
rs1256125915 688 dbSNP
rs532472607 688 dbSNP
rs946222129 693 dbSNP
rs1286401130 703 dbSNP
rs1469484443 704 dbSNP
rs893297796 707 dbSNP
rs1406149911 710 dbSNP
rs1416322497 711 dbSNP
rs1174359228 717 dbSNP
rs1054736288 723 dbSNP
rs937574446 724 dbSNP
rs1210191217 726 dbSNP
rs923616471 750 dbSNP
rs927313934 752 dbSNP
rs981449906 756 dbSNP
rs1336855261 762 dbSNP
rs1353608836 763 dbSNP
rs965323127 766 dbSNP
rs561375072 776 dbSNP
rs1278078254 777 dbSNP
rs1019954373 787 dbSNP
rs1307620815 799 dbSNP
rs1237153887 803 dbSNP
rs192730132 806 dbSNP
rs534477382 807 dbSNP
rs1206656221 808 dbSNP
rs188235192 812 dbSNP
rs1437162413 825 dbSNP
rs972829391 827 dbSNP
rs554116965 829 dbSNP
rs1179407365 833 dbSNP
rs539000440 835 dbSNP
rs1248186417 836 dbSNP
rs1455769419 845 dbSNP
rs151109482 846 dbSNP
rs1394678481 855 dbSNP
rs1433000438 857 dbSNP
rs1400718554 861 dbSNP
rs1397841208 868 dbSNP
rs985375163 868 dbSNP
rs1327297156 869 dbSNP
rs1333151220 876 dbSNP
rs753160579 881 dbSNP
rs3203648 888 dbSNP
rs1230065055 903 dbSNP
rs998280128 908 dbSNP
rs1156714731 916 dbSNP
rs902149998 925 dbSNP
rs773557173 926 dbSNP
rs538437426 927 dbSNP
rs6852042 931 dbSNP
rs1252678958 937 dbSNP
rs1452739227 945 dbSNP
rs761913866 948 dbSNP
rs893348558 951 dbSNP
rs1044682390 952 dbSNP
rs753504449 954 dbSNP
rs1397300794 956 dbSNP
rs1462350090 963 dbSNP
rs185362685 963 dbSNP
rs1391850074 966 dbSNP
rs1436760439 975 dbSNP
rs76862247 976 dbSNP
rs906118136 983 dbSNP
rs566163563 998 dbSNP
rs1325384938 999 dbSNP
rs1487968358 999 dbSNP
rs551372472 1004 dbSNP
rs1045953366 1010 dbSNP
rs1224581485 1014 dbSNP
rs950122962 1017 dbSNP
rs1054655608 1028 dbSNP
rs1284016464 1032 dbSNP
rs1212841550 1041 dbSNP
rs1213611982 1043 dbSNP
rs936425399 1050 dbSNP
rs1207079643 1059 dbSNP
rs1262659971 1066 dbSNP
rs1446551214 1067 dbSNP
rs1191101420 1072 dbSNP
rs1420742610 1080 dbSNP
rs1349302670 1082 dbSNP
rs1475784455 1089 dbSNP
rs193070408 1090 dbSNP
rs1217902233 1091 dbSNP
rs973265503 1095 dbSNP
rs188923740 1096 dbSNP
rs1271518177 1100 dbSNP
rs1380092897 1103 dbSNP
rs183417487 1120 dbSNP
rs1314104638 1130 dbSNP
rs1356025466 1139 dbSNP
rs1400252023 1147 dbSNP
rs760174085 1152 dbSNP
rs1331001086 1154 dbSNP
rs773028271 1166 dbSNP
rs74956793 1179 dbSNP
rs1436480344 1180 dbSNP
rs1261595198 1182 dbSNP
rs1359730573 1184 dbSNP
rs985363460 1188 dbSNP
rs1259640632 1190 dbSNP
rs953859500 1193 dbSNP
rs772116364 1196 dbSNP
rs953988125 1201 dbSNP
rs1255995733 1208 dbSNP
rs1421404451 1211 dbSNP
rs761645867 1217 dbSNP
rs867529154 1225 dbSNP
rs774169595 1228 dbSNP
rs78377468 1234 dbSNP
rs561859310 1235 dbSNP
rs1375479845 1236 dbSNP
rs1413599415 1237 dbSNP
rs28555653 1249 dbSNP
rs1016101854 1256 dbSNP
rs141584260 1257 dbSNP
rs560352379 1258 dbSNP
rs1305946847 1265 dbSNP
rs1316572678 1266 dbSNP
rs1238186619 1269 dbSNP
rs1282695410 1277 dbSNP
rs1486284533 1282 dbSNP
rs1348746618 1286 dbSNP
rs1210233627 1289 dbSNP
rs1237346155 1303 dbSNP
rs971819766 1313 dbSNP
rs1022993027 1331 dbSNP
rs1250196364 1333 dbSNP
rs1416972328 1334 dbSNP
rs34001017 1336 dbSNP
rs746110085 1340 dbSNP
rs1395287989 1371 dbSNP
rs545409244 1372 dbSNP
rs1433623892 1373 dbSNP
rs1171197664 1375 dbSNP
rs1356215852 1378 dbSNP
rs781334638 1379 dbSNP
rs1001715516 1382 dbSNP
rs1332440218 1384 dbSNP
rs1442795901 1388 dbSNP
rs770916195 1391 dbSNP
rs1371992549 1401 dbSNP
rs1316971992 1413 dbSNP
rs1275742854 1418 dbSNP
rs1416161438 1425 dbSNP
rs999433672 1427 dbSNP
rs372245859 1428 dbSNP
rs1302131069 1434 dbSNP
rs902228692 1437 dbSNP
rs574279072 1438 dbSNP
rs1215880583 1452 dbSNP
rs1046427786 1455 dbSNP
rs1453416187 1456 dbSNP
rs577913197 1459 dbSNP
rs190912041 1461 dbSNP
rs147871551 1462 dbSNP
rs1352636204 1465 dbSNP
rs1462825444 1471 dbSNP
rs1037040162 1473 dbSNP
rs573943573 1477 dbSNP
rs1395569144 1479 dbSNP
rs1421847315 1482 dbSNP
rs1440419159 1483 dbSNP
rs368543924 1487 dbSNP
rs1424413300 1496 dbSNP
rs765594439 1497 dbSNP
rs932563171 1498 dbSNP
rs1295516334 1499 dbSNP
rs932517104 1502 dbSNP
rs1413198269 1503 dbSNP
rs1467788285 1518 dbSNP
rs1218881857 1531 dbSNP
rs777699513 1537 dbSNP
rs922445773 1538 dbSNP
rs1481929614 1550 dbSNP
rs1185366165 1559 dbSNP
rs1233789669 1563 dbSNP
rs534091043 1575 dbSNP
rs1457038005 1576 dbSNP
rs1476140368 1583 dbSNP
rs1165443850 1584 dbSNP
rs1416858352 1589 dbSNP
rs1255685981 1592 dbSNP
rs1425643654 1601 dbSNP
rs908600908 1606 dbSNP
rs981912182 1615 dbSNP
rs375497243 1624 dbSNP
rs1347125618 1626 dbSNP
rs1311424508 1627 dbSNP
rs566251342 1628 dbSNP
rs531483217 1632 dbSNP
rs1226516430 1634 dbSNP
rs3172586 1636 dbSNP
rs1375520452 1638 dbSNP
rs1339166791 1645 dbSNP
rs1417134654 1653 dbSNP
rs748637468 1654 dbSNP
rs989165003 1662 dbSNP
rs971497913 1666 dbSNP
rs1022961962 1667 dbSNP
rs1226909973 1669 dbSNP
rs1012959739 1670 dbSNP
rs1317138578 1671 dbSNP
rs551142923 1674 dbSNP
rs1214528697 1684 dbSNP
rs560917625 1703 dbSNP
rs957669137 1710 dbSNP
rs1188615189 1717 dbSNP
rs1256659629 1723 dbSNP
rs1474110676 1725 dbSNP
rs1397865917 1727 dbSNP
rs1328115192 1733 dbSNP
rs779454517 1741 dbSNP
rs1410521729 1749 dbSNP
rs1001934691 1754 dbSNP
rs1033271584 1759 dbSNP
rs1349343882 1761 dbSNP
rs1158534978 1762 dbSNP
rs1162827762 1768 dbSNP
rs1358664895 1769 dbSNP
rs970253368 1772 dbSNP
rs186799882 1776 dbSNP
rs1014801133 1777 dbSNP
rs753561774 1784 dbSNP
rs1446372634 1789 dbSNP
rs1281626835 1794 dbSNP
rs368282183 1802 dbSNP
rs1019135246 1818 dbSNP
rs1255306031 1824 dbSNP
rs1037664756 1828 dbSNP
rs1005523691 1831 dbSNP
rs1488633144 1835 dbSNP
rs888435337 1842 dbSNP
rs1279527759 1843 dbSNP
rs1008381215 1845 dbSNP
rs1183791874 1847 dbSNP
rs144770459 1852 dbSNP
rs550897234 1854 dbSNP
rs1049344609 1857 dbSNP
rs932738676 1864 dbSNP
rs922462055 1868 dbSNP
rs1174339458 1878 dbSNP
rs932325948 1891 dbSNP
rs1309817398 1892 dbSNP
rs182118990 1902 dbSNP
rs1040892627 1905 dbSNP
rs945166193 1907 dbSNP
rs1355514464 1913 dbSNP
rs1374333260 1915 dbSNP
rs561900194 1918 dbSNP
rs548800700 1930 dbSNP
rs1305406093 1933 dbSNP
rs1372638137 1933 dbSNP
rs1234467871 1940 dbSNP
rs913838584 1950 dbSNP
rs989382227 1954 dbSNP
rs149162436 1955 dbSNP
rs1273578510 1956 dbSNP
rs1291854002 1966 dbSNP
rs1437036911 1972 dbSNP
rs1196460988 1973 dbSNP
rs1236654668 1978 dbSNP
rs908357396 1980 dbSNP
rs1194404124 1984 dbSNP
rs1377110614 1985 dbSNP
rs528270197 1987 dbSNP
rs1170171828 1992 dbSNP
rs926274142 2008 dbSNP
rs1397765529 2011 dbSNP
rs981330361 2028 dbSNP
rs1158516894 2029 dbSNP
rs1418440031 2039 dbSNP
rs1441153275 2041 dbSNP
rs560639031 2057 dbSNP
rs774668156 2058 dbSNP
rs1328878309 2071 dbSNP
rs916002017 2093 dbSNP
rs545131382 2098 dbSNP
rs1216637923 2099 dbSNP
rs3202899 2112 dbSNP
rs1214587338 2113 dbSNP
rs1266885323 2115 dbSNP
rs1449953188 2121 dbSNP
rs1195336696 2123 dbSNP
rs562618518 2127 dbSNP
rs1433407243 2132 dbSNP
rs1477772926 2149 dbSNP
rs1266153436 2152 dbSNP
rs754137371 2164 dbSNP
rs559987927 2165 dbSNP
rs961813692 2168 dbSNP
rs1318393967 2174 dbSNP
rs149918979 2176 dbSNP
rs890840675 2181 dbSNP
rs544537043 2182 dbSNP
rs1005741366 2190 dbSNP
rs1233786910 2195 dbSNP
rs1335264495 2197 dbSNP
rs888489224 2214 dbSNP
rs75525116 2219 dbSNP
rs1354501167 2220 dbSNP
rs996769716 2222 dbSNP
rs1384154221 2224 dbSNP
rs1341162795 2225 dbSNP
rs1192162187 2231 dbSNP
rs3733630 2231 dbSNP
rs1164434851 2234 dbSNP
rs1398683592 2236 dbSNP
rs1041504114 2245 dbSNP
rs1455006665 2249 dbSNP
rs1377870784 2252 dbSNP
rs1158687285 2255 dbSNP
rs939923556 2259 dbSNP
rs1417268728 2263 dbSNP
rs1314664694 2268 dbSNP
rs376198607 2271 dbSNP
rs761839753 2273 dbSNP
rs1465808945 2279 dbSNP
rs1310295292 2280 dbSNP
rs1338975855 2281 dbSNP
rs1376307169 2288 dbSNP
rs887071010 2294 dbSNP
rs1045932966 2297 dbSNP
rs1173471146 2298 dbSNP
rs1214467075 2303 dbSNP
rs949872812 2306 dbSNP
rs915969510 2309 dbSNP
rs945243909 2310 dbSNP
rs892274544 2317 dbSNP
rs540429511 2332 dbSNP
rs1421211137 2333 dbSNP
rs925935566 2335 dbSNP
rs1379245974 2342 dbSNP
rs936563786 2344 dbSNP
rs926489488 2352 dbSNP
rs1465464805 2363 dbSNP
rs1300903843 2370 dbSNP
rs980434344 2383 dbSNP
rs987570094 2387 dbSNP
rs1310277167 2398 dbSNP
rs774223616 2401 dbSNP
rs1029138250 2412 dbSNP
rs1305696894 2417 dbSNP
rs1200976618 2419 dbSNP
rs996539542 2424 dbSNP
rs917686191 2428 dbSNP
rs1349291535 2432 dbSNP
rs573313009 2440 dbSNP
rs972212434 2442 dbSNP
rs557872319 2444 dbSNP
rs961593248 2455 dbSNP
rs1015714343 2462 dbSNP
rs984373628 2465 dbSNP
rs1481831838 2469 dbSNP
rs3822289 2473 dbSNP
rs762664684 2479 dbSNP
rs1437420536 2480 dbSNP
rs1195008830 2483 dbSNP
rs996822226 2500 dbSNP
rs901141262 2504 dbSNP
rs1019718333 2513 dbSNP
rs1010062815 2514 dbSNP
rs1173894729 2517 dbSNP
rs1462306441 2537 dbSNP
rs111762120 2538 dbSNP
rs886992882 2542 dbSNP
rs1318930354 2546 dbSNP
rs892332628 2547 dbSNP
rs1444802390 2548 dbSNP
rs555997070 2552 dbSNP
rs1368430054 2553 dbSNP
rs535409348 2554 dbSNP
rs1216805744 2556 dbSNP
rs146261891 2565 dbSNP
rs1335392712 2567 dbSNP
rs905126546 2571 dbSNP
rs1219696232 2579 dbSNP
rs1395991352 2581 dbSNP
rs1400476989 2583 dbSNP
rs1300319839 2587 dbSNP
rs1456199252 2596 dbSNP
rs370610381 2601 dbSNP
rs1055667530 2603 dbSNP
rs867826675 2610 dbSNP
rs1487879398 2616 dbSNP
rs1188876792 2624 dbSNP
rs771239556 2631 dbSNP
rs1429033527 2632 dbSNP
rs1169752847 2638 dbSNP
rs1423976055 2639 dbSNP
rs1169520419 2640 dbSNP
rs926100049 2647 dbSNP
rs949107628 2654 dbSNP
rs1042072434 2655 dbSNP
rs946080126 2656 dbSNP
rs1476520963 2668 dbSNP
rs917557482 2672 dbSNP
rs1369719946 2675 dbSNP
rs747173732 2686 dbSNP
rs1401109218 2687 dbSNP
rs546872541 2694 dbSNP
rs528305073 2695 dbSNP
rs34635660 2700 dbSNP
rs1253788172 2706 dbSNP
rs551899804 2709 dbSNP
rs953656774 2712 dbSNP
rs1458052613 2717 dbSNP
rs922094780 2721 dbSNP
rs191342216 2730 dbSNP
rs952858814 2731 dbSNP
rs921532347 2734 dbSNP
rs1243320397 2738 dbSNP
rs112170112 2747 dbSNP
rs1488310407 2748 dbSNP
rs1197015553 2749 dbSNP
rs1192887263 2751 dbSNP
rs1260868805 2757 dbSNP
rs1358510835 2758 dbSNP
rs749400195 2761 dbSNP
rs1414873879 2764 dbSNP
rs146565524 2765 dbSNP
rs1347066924 2766 dbSNP
rs555677282 2766 dbSNP
rs976058186 2772 dbSNP
rs1298136313 2773 dbSNP
rs1016690895 2789 dbSNP
rs965446474 2792 dbSNP
rs1400045131 2805 dbSNP
rs1020024754 2808 dbSNP
rs1285139154 2809 dbSNP
rs1378049398 2812 dbSNP
rs1226291016 2814 dbSNP
rs1330211276 2819 dbSNP
rs1285859879 2832 dbSNP
rs1353822003 2839 dbSNP
rs1009536620 2845 dbSNP
rs562965143 2856 dbSNP
rs951099505 2869 dbSNP
rs1486603785 2872 dbSNP
rs1210619164 2874 dbSNP
rs1024001788 2876 dbSNP
rs544219215 2879 dbSNP
rs1471664697 2883 dbSNP
rs956779030 2884 dbSNP
rs1180357888 2885 dbSNP
rs1410366735 2888 dbSNP
rs1440401663 2891 dbSNP
rs1366579244 2894 dbSNP
rs1359246110 2900 dbSNP
rs1180450607 2903 dbSNP
rs1032402031 2904 dbSNP
rs1335318161 2908 dbSNP
rs1440027891 2921 dbSNP
rs534260455 2929 dbSNP
rs1446201936 2930 dbSNP
rs1196952131 2941 dbSNP
rs1453591029 2943 dbSNP
rs1377184036 2955 dbSNP
rs770810431 2956 dbSNP
rs1306428695 2971 dbSNP
rs186534380 2974 dbSNP
rs905013406 2980 dbSNP
rs1290666787 2988 dbSNP
rs1000037648 2990 dbSNP
rs1440498570 2997 dbSNP
rs1206271137 3010 dbSNP
rs540513656 3016 dbSNP
rs1240329873 3020 dbSNP
rs1458369440 3021 dbSNP
rs1219839694 3025 dbSNP
rs1013920323 3028 dbSNP
rs1378515276 3042 dbSNP
rs896189734 3045 dbSNP
rs1036448881 3064 dbSNP
rs940330212 3069 dbSNP
rs1425005073 3072 dbSNP
rs908985297 3077 dbSNP
rs946144895 3090 dbSNP
rs573428255 3104 dbSNP
rs1354338283 3108 dbSNP
rs911882188 3117 dbSNP
rs748690714 3121 dbSNP
rs1241533538 3128 dbSNP
rs199498776 3139 dbSNP
rs202225406 3139 dbSNP
rs558044754 3139 dbSNP
rs779509367 3140 dbSNP
rs755398680 3143 dbSNP
rs932232636 3155 dbSNP
rs922189809 3181 dbSNP
rs973506894 3182 dbSNP
rs371377600 3189 dbSNP
rs942226448 3191 dbSNP
rs909600829 3202 dbSNP
rs921429164 3215 dbSNP
rs545920529 3226 dbSNP
rs1439539400 3229 dbSNP
rs1236524862 3231 dbSNP
rs1453409407 3231 dbSNP
rs982534639 3241 dbSNP
rs1199673631 3243 dbSNP
rs181841950 3245 dbSNP
rs975723613 3266 dbSNP
rs951234043 3269 dbSNP
rs1477313749 3270 dbSNP
rs1023972283 3272 dbSNP
rs1173327227 3272 dbSNP
rs575261166 3274 dbSNP
rs1168110285 3277 dbSNP
rs1392350497 3282 dbSNP
rs1322287464 3284 dbSNP
rs966021308 3285 dbSNP
rs1034277522 3294 dbSNP
rs191940523 3303 dbSNP
rs143466074 3304 dbSNP
rs904335593 3311 dbSNP
rs1216501159 3312 dbSNP
rs988562952 3312 dbSNP
rs1210562881 3313 dbSNP
rs956660906 3313 dbSNP
rs1032454456 3315 dbSNP
rs1000931130 3322 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgAGGUCAGAGCUGCAAGGGCCCc 5'
            | ||  ||| :|  ||||||| 
Target 5' acUACAACCUCUGC-CUCCCGGGu 3'
 		4 - 26
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177600. RNA binding protein: AGO2. Condition:p53_V_Ago_CLIP_2_2 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgAGGUCAGAGCUGCAAGGGCCCc 5'
            | ||  ||| :|  ||||||| 
Target 5' acUACAACCUCUGC-CUCCCGGGu 3'
 		4 - 26
Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Prostate Tissue
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRX1760638. RNA binding protein: AGO2. Condition:AGO-CLIP-PC3-miR148 ...

- Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al., 2016, Neoplasia (New York, N.Y.).

Article - Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al.
- Neoplasia (New York, N.Y.), 2016
MicroRNA (miRNA) deregulation in prostate cancer (PCa) contributes to PCa initiation and metastatic progression. To comprehensively define the cancer-associated changes in miRNA targeting and function in commonly studied models of PCa, we performed photoactivatable ribonucleoside-enhanced cross-linking immunoprecipitation of the Argonaute protein in a panel of PCa cell lines modeling different stages of PCa progression. Using this comprehensive catalogue of miRNA targets, we analyzed miRNA targeting on known drivers of PCa and examined tissue-specific and stage-specific pathway targeting by miRNAs. We found that androgen receptor is the most frequently targeted PCa oncogene and that miR-148a targets the largest number of known PCa drivers. Globally, tissue-specific and stage-specific changes in miRNA targeting are driven by homeostatic response to active oncogenic pathways. Our findings indicate that, even in advanced PCa, the miRNA pool adapts to regulate continuing alterations in the cancer genome to balance oncogenic molecular changes. These findings are important because they are the first to globally characterize miRNA changes in PCa and demonstrate how the miRNA target spectrum responds to staged tumorigenesis.
LinkOut: [PMID: 27292025]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000361717.3 | 3UTR | CUCACUACAACCUCUGCCUCCCGGGUUCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
228 hsa-miR-1247-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT107246 PTGES2 prostaglandin E synthase 2 2 2
MIRT118004 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 6
MIRT345983 BIRC5 baculoviral IAP repeat containing 5 2 4
MIRT369967 ZNF264 zinc finger protein 264 2 2
MIRT451350 ZNF573 zinc finger protein 573 2 4
MIRT451367 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451450 ZNF556 zinc finger protein 556 2 4
MIRT451766 ZNF611 zinc finger protein 611 2 6
MIRT452065 ZNF585B zinc finger protein 585B 2 8
MIRT452346 TG thyroglobulin 2 2
MIRT452519 TFDP2 transcription factor Dp-2 2 6
MIRT452631 FAM162A family with sequence similarity 162 member A 2 2
MIRT452896 PSD4 pleckstrin and Sec7 domain containing 4 2 4
MIRT453263 PARP11 poly(ADP-ribose) polymerase family member 11 2 2
MIRT453567 RDH13 retinol dehydrogenase 13 2 2
MIRT453911 GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 2 4
MIRT454576 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT454859 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455094 NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2 2
MIRT455790 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT455932 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT456213 LIX1L limb and CNS expressed 1 like 2 4
MIRT456238 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2 6
MIRT456279 HRNR hornerin 2 2
MIRT456665 TIFA TRAF interacting protein with forkhead associated domain 2 2
MIRT457088 XPNPEP3 X-prolyl aminopeptidase 3 2 2
MIRT457322 DUSP19 dual specificity phosphatase 19 2 2
MIRT457695 ZNF587 zinc finger protein 587 2 4
MIRT458160 LYRM4 LYR motif containing 4 2 6
MIRT458465 SNX22 sorting nexin 22 2 8
MIRT458504 MARVELD2 MARVEL domain containing 2 2 2
MIRT458514 GSG2 histone H3 associated protein kinase 2 10
MIRT458645 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT458823 ZNF843 zinc finger protein 843 2 4
MIRT459156 NARF nuclear prelamin A recognition factor 2 2
MIRT459182 HSPA6 heat shock protein family A (Hsp70) member 6 2 4
MIRT459374 MPLKIP M-phase specific PLK1 interacting protein 2 6
MIRT459552 BTD biotinidase 2 2
MIRT459756 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT459860 SVOP SV2 related protein 2 8
MIRT460020 DTX3L deltex E3 ubiquitin ligase 3L 2 6
MIRT460233 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT460275 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460461 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460540 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT460551 IFNAR1 interferon alpha and beta receptor subunit 1 2 6
MIRT460978 STK17B serine/threonine kinase 17b 2 2
MIRT461421 CTSL2 cathepsin V 1 2
MIRT461960 C3 complement C3 2 4
MIRT462529 DHODH dihydroorotate dehydrogenase (quinone) 2 6
MIRT462864 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT462917 ZNRF3 zinc and ring finger 3 2 2
MIRT463022 ZNF70 zinc finger protein 70 2 2
MIRT463074 ZNF639 zinc finger protein 639 2 2
MIRT463130 ZNF451 zinc finger protein 451 2 4
MIRT463627 YY1 YY1 transcription factor 2 2
MIRT467015 SSBP2 single stranded DNA binding protein 2 2 2
MIRT467127 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 8
MIRT468526 SERTAD2 SERTA domain containing 2 2 4
MIRT468584 SERBP1 SERPINE1 mRNA binding protein 1 2 6
MIRT469540 RBBP8 RB binding protein 8, endonuclease 2 2
MIRT469876 PURB purine rich element binding protein B 2 4
MIRT471577 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT472110 NME2 NME/NM23 nucleoside diphosphate kinase 2 2 2
MIRT472127 NME1-NME2 NME1-NME2 readthrough 2 2
MIRT472423 NCKAP1 NCK associated protein 1 2 2
MIRT472829 MTMR10 myotubularin related protein 10 2 4
MIRT473022 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT473408 MDM4 MDM4, p53 regulator 2 2
MIRT474122 LIPC lipase C, hepatic type 2 2
MIRT474927 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT476807 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT478006 DNAL1 dynein axonemal light chain 1 2 2
MIRT479200 CLCN5 chloride voltage-gated channel 5 2 6
MIRT479671 CCSER2 coiled-coil serine rich protein 2 2 2
MIRT479917 CCDC117 coiled-coil domain containing 117 2 6
MIRT479977 CARD10 caspase recruitment domain family member 10 2 2
MIRT480731 BPTF bromodomain PHD finger transcription factor 2 6
MIRT481100 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT481160 AVL9 AVL9 cell migration associated 2 6
MIRT481393 ATG12 autophagy related 12 2 2
MIRT481433 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT482083 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT484667 HOXD3 homeobox D3 2 4
MIRT485940 ECSIT ECSIT signalling integrator 2 4
MIRT485950 BRSK1 BR serine/threonine kinase 1 2 2
MIRT487600 NKD2 naked cuticle homolog 2 2 4
MIRT487666 HPCAL1 hippocalcin like 1 2 4
MIRT489966 GNB2 G protein subunit beta 2 2 2
MIRT490332 ANK1 ankyrin 1 2 4
MIRT491314 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT493193 MINK1 misshapen like kinase 1 2 4
MIRT493300 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT493816 FSCN1 fascin actin-bundling protein 1 2 2
MIRT496977 RPS6KA2 ribosomal protein S6 kinase A2 2 2
MIRT512229 ATXN3 ataxin 3 2 6
MIRT515141 ZNF799 zinc finger protein 799 2 4
MIRT516647 SMC5 structural maintenance of chromosomes 5 2 2
MIRT517952 TRIM59 tripartite motif containing 59 2 2
MIRT520971 SPPL2A signal peptide peptidase like 2A 2 4
MIRT521569 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT522918 KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 2 2
MIRT532713 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT540809 SLC35F5 solute carrier family 35 member F5 2 2
MIRT550734 PMPCA peptidase, mitochondrial processing alpha subunit 2 4
MIRT551293 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 4
MIRT559740 ACOX1 acyl-CoA oxidase 1 2 2
MIRT564410 EMILIN2 elastin microfibril interfacer 2 2 2
MIRT565240 TRAF6 TNF receptor associated factor 6 2 2
MIRT568911 ATP6V1B1 ATPase H+ transporting V1 subunit B1 2 2
MIRT575232 Fut1 fucosyltransferase 1 2 2
MIRT576224 Srsf1 serine/arginine-rich splicing factor 1 2 2
MIRT607724 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT608090 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT613920 POU3F1 POU class 3 homeobox 1 2 2
MIRT618520 SELPLG selectin P ligand 2 2
MIRT624703 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT624770 AKR1D1 aldo-keto reductase family 1 member D1 2 2
MIRT625720 SPI1 Spi-1 proto-oncogene 2 2
MIRT629975 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT631356 ZFP82 ZFP82 zinc finger protein 2 2
MIRT631426 CDNF cerebral dopamine neurotrophic factor 2 2
MIRT631665 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT631735 SF3B1 splicing factor 3b subunit 1 2 2
MIRT632334 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632419 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632531 PSMB2 proteasome subunit beta 2 2 2
MIRT633264 LDLR low density lipoprotein receptor 2 2
MIRT634327 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634753 CRCP CGRP receptor component 2 2
MIRT635412 KIAA1614 KIAA1614 2 2
MIRT636281 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636291 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT640265 FANCA Fanconi anemia complementation group A 2 2
MIRT641738 TXNL1 thioredoxin like 1 2 2
MIRT643276 ZNF566 zinc finger protein 566 2 2
MIRT643528 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643555 C11orf70 chromosome 11 open reading frame 70 2 2
MIRT647027 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647298 RBM43 RNA binding motif protein 43 2 2
MIRT648124 SEMA3E semaphorin 3E 2 4
MIRT648611 TPCN2 two pore segment channel 2 2 2
MIRT648717 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT649425 CDC14B cell division cycle 14B 2 2
MIRT650029 DSG3 desmoglein 3 2 2
MIRT650281 TAS2R5 taste 2 receptor member 5 2 2
MIRT650529 CCDC77 coiled-coil domain containing 77 2 2
MIRT654240 RNF115 ring finger protein 115 2 2
MIRT657032 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT658408 FAM212B family with sequence similarity 212 member B 2 2
MIRT659442 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT661080 FFAR2 free fatty acid receptor 2 2 2
MIRT661529 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661876 PDLIM5 PDZ and LIM domain 5 2 2
MIRT662100 ZNF419 zinc finger protein 419 2 2
MIRT662136 ZC3H8 zinc finger CCCH-type containing 8 2 2
MIRT663638 HM13 histocompatibility minor 13 2 2
MIRT663703 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663847 TRIM72 tripartite motif containing 72 2 2
MIRT664769 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665481 VSTM4 V-set and transmembrane domain containing 4 2 2
MIRT666533 RNF157 ring finger protein 157 2 2
MIRT668107 GK5 glycerol kinase 5 (putative) 2 2
MIRT668984 CKAP4 cytoskeleton associated protein 4 2 4
MIRT669742 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT671010 MOB4 MOB family member 4, phocein 2 2
MIRT671583 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT673261 INO80 INO80 complex subunit 2 2
MIRT673533 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT674714 FAM73A mitoguardin 1 2 2
MIRT675205 ZNF554 zinc finger protein 554 2 2
MIRT676488 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT676705 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676851 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT676855 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT676915 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT677000 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT677188 PDE12 phosphodiesterase 12 2 2
MIRT677473 SLC7A11 solute carrier family 7 member 11 2 2
MIRT677562 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677779 FKTN fukutin 2 2
MIRT677896 DCP1A decapping mRNA 1A 2 2
MIRT677996 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678239 HMGB1 high mobility group box 1 2 4
MIRT678313 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT678437 PDE4C phosphodiesterase 4C 2 2
MIRT678480 RNF222 ring finger protein 222 2 2
MIRT678591 ZNF91 zinc finger protein 91 2 2
MIRT678863 SLC7A14 solute carrier family 7 member 14 2 2
MIRT679241 LRP10 LDL receptor related protein 10 2 2
MIRT679388 WDR92 WD repeat domain 92 2 2
MIRT679501 ZNF106 zinc finger protein 106 2 2
MIRT679581 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679827 TMEM106B transmembrane protein 106B 2 2
MIRT679842 GPR75 G protein-coupled receptor 75 2 2
MIRT679860 ZFP30 ZFP30 zinc finger protein 2 2
MIRT680733 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT680922 STX2 syntaxin 2 2 2
MIRT680953 CEP104 centrosomal protein 104 2 2
MIRT681053 ZDBF2 zinc finger DBF-type containing 2 2 2
MIRT681967 TFCP2 transcription factor CP2 2 2
MIRT682010 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT682061 B4GALT7 beta-1,4-galactosyltransferase 7 2 4
MIRT682070 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT683356 SCARF1 scavenger receptor class F member 1 2 2
MIRT683699 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT684268 PRPF4 pre-mRNA processing factor 4 2 2
MIRT685500 MED16 mediator complex subunit 16 2 2
MIRT686876 SLC25A32 solute carrier family 25 member 32 2 2
MIRT690869 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691139 HJURP Holliday junction recognition protein 2 2
MIRT691195 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT691780 SLC24A4 solute carrier family 24 member 4 2 2
MIRT692901 MPL MPL proto-oncogene, thrombopoietin receptor 2 2
MIRT694551 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT695421 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT695956 FANCM Fanconi anemia complementation group M 2 2
MIRT696615 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT700682 PPAP2B phospholipid phosphatase 3 2 2
MIRT701215 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT702196 LRRC58 leucine rich repeat containing 58 2 2
MIRT702837 HOOK3 hook microtubule tethering protein 3 2 2
MIRT703652 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT705679 ANKRD40 ankyrin repeat domain 40 2 2
MIRT706650 SMIM19 small integral membrane protein 19 2 2
MIRT711087 NEUROD2 neuronal differentiation 2 2 2
MIRT724961 PTK6 protein tyrosine kinase 6 2 2
MIRT735597 BCL6 B-cell CLL/lymphoma 6 1 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1247 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-1247 Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780CIS)
hsa-mir-1247 Sorafenib 216239 NSC747971 approved sensitive High Hepatocellular Carcinoma tissue
hsa-mir-1247 Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-mir-1247 Androstenedione 6128 NSC9563 resistant cell line (MCF-7)
hsa-mir-1247 Androstenedione+Anastrozole resistant cell line (MCF-7)
hsa-mir-1247 Androstenedione+Letrozole resistant cell line (MCF-7)
hsa-mir-1247 Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-mir-1247 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-mir-1247 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1247-3p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (SW1990)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-1247-3p Yuanhuadine 6440572 resistant High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-1247-3p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-1247-3p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-1247-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-1247-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1247-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-1247-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-1247-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-1247-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-1247-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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