miRTarBase - #MIRT456891


—
pre-miRNA Information
pre-miRNA hsa-mir-4665   
Genomic Coordinates chr9: 6007826 - 6007904
Description Homo sapiens miR-4665 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4665-5p
Sequence 10| CUGGGGGACGCGUGAGCGCGAGC |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs901542342 1 dbSNP
rs1170299887 2 dbSNP
rs747546692 3 dbSNP
rs1260840238 4 dbSNP
rs1377576716 5 dbSNP
rs1349863083 6 dbSNP
rs933050749 7 dbSNP
rs1236802314 11 dbSNP
rs1050148325 12 dbSNP
rs1198393802 14 dbSNP
rs771241090 19 dbSNP
rs1258201615 20 dbSNP
rs1485839367 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DDA1   
Synonyms C19orf58, PCIA1
Description DET1 and DDB1 associated 1
Transcript NM_024050   
Expression
Putative miRNA Targets on DDA1
3'UTR of DDA1
(miRNA target sites are highlighted)		 
>DDA1|NM_024050|3'UTR
   1 GACTCTCAACTCCACAGGCGCCTCCTGCCAGGTCTGCTCCTCGGTCGCCCACCCGCCTGCCCGCCATGTGTAAGCACCCC
  81 GCCCGCCCGCCTCCCTGCCGGCCCATCCACACCCTGCGTCCACACCACTTCCAACCTCATAGGAGCCGATGTATTTATTT
 161 TCCTTGAGTTTTTATTTATGCTGTAACCTGTATCAAGCGTTGGTTAAAGGGGACATCAGACCCAGTAGTGTGATGTTGGT
 241 AGATGCTTTTTAAAAAAAACAACATTGTCCCCCCGACCCCCGCCTTCCATCGGGCCAGTTCCCCGATTCCTGCCCCCAGT
 321 TCTCCAGAGAACCAGAGTGTGTCTGTGAGAGTCTCTAGCGGGGGCTTTACTGTGGCCGGGCGACAGGGGCGGGCCCGGGG
 401 TGGCCTGACCTACCAGGACAGCCGAGTGGCCTTCTCCCCCCCAACACCGGTCCAGGCCATTGAGACTCGGTCTTGTCCCA
 481 CGCTTCGCCCGGAACTTTCCCATGCCCAGGCCTCACTCAGCGTGCACGCACGTTGGGGAGAAGTCGGCCCTTGGGATCTT
 561 TCTCTTGAGTCATTTTATTTTTATCATGGACTAGTGCGTGCTCCGTGTCCACCCCAATAAAAGGGTCTTTCCTACTTGAC
 641 CTCGCGTCTTTGCTCCACACACCTTGGCTGCAGAGGACGGAGCCCCTGGGAGTCATCCCTGTTGTCACCAAGAGGAGTGA
 721 GAAGGGCCCCCCACGCCAGGGGCCCCAGGACCGGCTGGATTCTCTCGTGGGCTTGCTGAGGCCACCATGTTCAAGGCCAA
 801 GACCTGCCTGGACCATCCCCTCTGCCTCTCCTGTCAAGGTGACCCCAAGGACAGGTCATTCCTGAGAGACGGTCCATGGT
 881 GCCAAGGATGGAGCGGGGTCAGCCCCCTGCCTGGGATACCGCCAAGCAGGGCAGCGCACCTGTCAGACACCGCAGAGATG
 961 GCCGGCCTCATCCGGGGGCCTGGGGTCTCTGGCCTCTGCTGCTCCCCTGAGGCATGGTGACAGTACAGACGGCATCTGGC
1041 CGGTCTTGCTGTCCTAGGTGGTGGCCTCACCCTTGCTGGGTCATAGAGGAGCTGTACAGAAGGTTGGCACCTGGCAGTTG
1121 GCATGTGCCATGGCCGCTCATGGGGACCCCTCTTCCGCCAGCTGGGCTGGGTTTGGGGCTGAGCTTGGGTATGTAGGGGT
1201 GTTCGGGCTCTGGGCAGAAGGTTTGTGGCCCTGACCACTGAGCCTGGGGCTGGGGGAACACCGCTTCTCCCCTTATTGCC
1281 CCCACTGGTGGTGGTGGGGATCTCAGTTTTCTTTTGTTTTGTTTTGTTTGTTTGTTTGAGTTGGGGTCTTGTACTCTTTC
1361 CCAGGCTGGAGTGCAGTGGCGTAATCACAGCTCACTGCAGCCTCGACCTCAAGCCTTCCTCCCACCTCAGCCTTCCAAGC
1441 CGCTGGGACCACAGGCACCCACCACCATGCCTGGCTAATTTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTCTCCCAG
1521 GCTGGAGTGCAGTGGCAAGATCTCAGCTCACTACAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTACCTCAGCCTCCT
1601 GAGTAGCTGGGATTACACGCGTGCGCCCCTACACCCAGCTAATTTTTCTATTTTTAGTGGAGACGGCGTTTTGTCATGTT
1681 GGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGCTTCGCCTGCCTCGGCCTCCCAAAGTGCTGTGACCGCACCTGGCTG
1761 CCTGGCTAATATTTTAAAAATTTTTTGTAGAGACAGGGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCA
1841 AGTCATCCACCTTCCTCAGCCTCCCAAAGTGCTGGGGTTACAGACGTGAACCACCGTGCCTGGCAGAGGTCTCTGTTTTG
1921 AGAGCTGAGTCTGAGGGCGTTGGGATGGTGTAGGGTTGGGCCACAGAGCTAGCAGACACTCCGGGCTATGGAGGGTCCGC
2001 CTGCCCCAGATTCCACTGTGGAGGGCCCTGCCTGTGTCAGACCCTCGGGCCTAGGCGGCCCATCTCTCCCAAGGACGGAG
2081 AGTGCCAGGGTGGGCTCCCGTCCTACACAAGGAGTGGCTGACCAGGCCCAGGCACAGCACAGCCACCCTGCTGTACCTCC
2161 CAGCTCCCGGCAGTGTCTACACCACAGTGATGGTGCTACAGGGGCCATGTGGTCACAGGACAGGTGGTCAGGAAATGCAC
2241 ACTTGACTGCGGTCGATGGTGCCGGGTCCGGCTGAATGCCCTGGAGGCTCCCAGGCCAGCTGGGGAGTCCCAGTCCCCAG
2321 GGTTGGTGTGACCTGGGCAGGCCTGCGGTGTCCATCTGTGAATGACTGAGATGGTGGGACTTCAGCTTCCAAGGCCAGGG
2401 GCCAGAGTGGGAGCAGGGGGCACTCCCGCCTTTCCCCTCGGCCTGTCTAGACCTCTCTGGCTCCCAGTTTCTGCTTTGAG
2481 TGGCTGGGGGCTGTCTCCTGCCTGTGCTGTCTGCCCGTCGCTCTGCAGGGCTGCTGGGCGGGCACCTCCTTCCCCTCCCC
2561 TACCTCAGCTCCCTCCTTTGGGGTCTGAGGGCTGTGCCCCAGCTTGCCTCCCTGTGGCCTCCCCCTAGAACCCCTGGGTC
2641 TGTCGGGACATGCCCCACCTGGCACACACACCCTGTGTAGCTCCCACTGCCTGTGGGAGGACGCTGGGCCCCTGAGCCGG
2721 CCTCTGTCTACCCCTCCTGCCTTTGGGGTCCCCTTTACCCCACTGTTCCCCCAAACTGCCTTCCACCTTCTCCGCCTTTG
2801 CACAGGCTGTTCTCCTGCCTCCAGTGAACTCTGACTTCTCCACAGCCTCCCAAAGGGCCCCTTGCTCACACTGGCCCAGC
2881 CCTGCAGCATGGCCATGTTGGTCTCTGAGCCTTAAGCCTTTGGATGTGGACACATTTGTCCTCTTCCTGAAAAATGTGAG
2961 GGTCTGAGAGGCCACGTTCCTGTTCCTGAGTCATACGACAGAGTCCCAGTGACTTGGGTCTGATGTCTGTCCCACAGTGG
3041 GACATCCCTGCTGCATCCCAATGCCACCCCGTGTCCTGGGGACACCCAAATGTGCCATTCTCTCAGTATCACAAGTCGGG
3121 GACTGCAGGAGGCTCAGGTGCCAGGTGCCTTCTGATGTTCATGCCACAAGCTCTTCCCACTGTCTCTGGCTCCCCAGACG
3201 ATGTTCCAGGAGGCGGGTGTGCCAGAAGGGGCCACGTCTTGCAAACCACCGCGCTGTCCTCTTTGAGAAGGAGTCTTACT
3281 CAGGACTGGGGCCTGTGCACACATTGTCGCCTCTTTTCAGCACTTAGAGATTCCTTCCTTTGTCTAGTGGCTGAAGCCAG
3361 GGCTGAAGTTGGCCTCCAAATCTGGGCCGTCTCAGAGGCGGCGCAGCCTGGAGTTTTCCATCTGTGGCCAAGACCCAGTT
3441 TTTGGGAGGAGGCCCTCATGGGTCAAGCCAGCCTGTACCAGGATGGGGGGAGGGGGTTCCCAACCTAGGCCCCAGCCACC
3521 CAGACTCCCCCACCCCCACTCCCTTTTCCACTGCTCTGACCTCGGGCACTGTTGAAATATAGTTTTTATTGCATTTCTGC
3601 CGTTTTACAAAAATATGACAAAATAAATTAAAAACAAATAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgAGCGCGAGUGCG----C-AGGGGGUc 5'
            || | :|:|| |    | ||||||| 
Target 5' ggTCCCCTTTACCCCACTGTTCCCCCAa 3'
 2747 - 2774 151.00 -17.10
2 
miRNA  3' cgAGCGCGAGUGCGCAGGGGGUc 5'
            || ||||   |:|||:|||| 
Target 5' agTCTCGCT---GTGTCTCCCAg 3'
 1501 - 1520 150.00 -28.40
3 
miRNA  3' cgagcgCGAGUGCG-C--AGGGGGUc 5'
                || ||| | |  ||||||| 
Target 5' gccccaGC-CACCCAGACTCCCCCAc 3'
 3509 - 3533 146.00 -17.43
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31562525 22 COSMIC
COSN28717926 23 COSMIC
COSN32074603 43 COSMIC
COSN30593942 63 COSMIC
COSN9349640 64 COSMIC
COSN1211875 77 COSMIC
COSN30603940 89 COSMIC
COSN6667313 293 COSMIC
COSN18000049 402 COSMIC
COSN16186512 628 COSMIC
COSN30271297 735 COSMIC
COSN25301135 865 COSMIC
COSN17037563 871 COSMIC
COSN6667314 974 COSMIC
COSN1211877 1234 COSMIC
COSN1211879 1382 COSMIC
COSN18756741 1494 COSMIC
COSN21439965 1803 COSMIC
COSN6138830 2263 COSMIC
COSN20894430 2520 COSMIC
COSN1211881 2936 COSMIC
COSN6138831 3082 COSMIC
COSN4777296 3253 COSMIC
COSN32095661 3409 COSMIC
COSN31534619 3520 COSMIC
COSN26572714 3573 COSMIC
COSN26573109 3603 COSMIC
COSN1211883 3636 COSMIC
COSN23784304 3643 COSMIC
rs1079098 2213 GWAS
rs77331626 3629 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1416578831 2 dbSNP
rs773275334 3 dbSNP
rs1437937197 4 dbSNP
rs747477450 5 dbSNP
rs757677187 9 dbSNP
rs1397694719 11 dbSNP
rs375115330 12 dbSNP
rs1340786394 17 dbSNP
rs369670034 20 dbSNP
rs1281980179 21 dbSNP
rs769984314 22 dbSNP
rs1301953293 30 dbSNP
rs59808827 32 dbSNP
rs1035912252 33 dbSNP
rs1283236956 35 dbSNP
rs1279452083 37 dbSNP
rs373319827 38 dbSNP
rs1218573178 39 dbSNP
rs1264167856 41 dbSNP
rs3745188 43 dbSNP
rs771953276 44 dbSNP
rs1239294151 45 dbSNP
rs1450050187 46 dbSNP
rs985400485 47 dbSNP
rs376535384 48 dbSNP
rs1379051738 50 dbSNP
rs760566274 52 dbSNP
rs569168062 55 dbSNP
rs144057498 56 dbSNP
rs1231245700 59 dbSNP
rs1016145351 64 dbSNP
rs1422212980 69 dbSNP
rs903900398 77 dbSNP
rs1340724603 78 dbSNP
rs878940508 81 dbSNP
rs929959340 82 dbSNP
rs918942739 84 dbSNP
rs147250555 85 dbSNP
rs888468655 86 dbSNP
rs1002159995 89 dbSNP
rs1314287209 90 dbSNP
rs1357262178 93 dbSNP
rs571272415 100 dbSNP
rs1034612132 101 dbSNP
rs1477052207 104 dbSNP
rs895986549 106 dbSNP
rs1447759926 107 dbSNP
rs377237894 109 dbSNP
rs1482887626 118 dbSNP
rs1215359403 119 dbSNP
rs1207117986 123 dbSNP
rs1308580653 125 dbSNP
rs1240668081 128 dbSNP
rs1278479022 137 dbSNP
rs140662627 148 dbSNP
rs943588787 149 dbSNP
rs1054364081 151 dbSNP
rs1443383506 155 dbSNP
rs1024717818 175 dbSNP
rs1349566302 184 dbSNP
rs966425551 191 dbSNP
rs763528058 199 dbSNP
rs945622318 200 dbSNP
rs1354915202 218 dbSNP
rs368646117 222 dbSNP
rs1032387909 232 dbSNP
rs1399695799 240 dbSNP
rs906554136 243 dbSNP
rs1004030859 251 dbSNP
rs1033809898 252 dbSNP
rs1472371139 252 dbSNP
rs190184101 253 dbSNP
rs1481142627 258 dbSNP
rs567226015 261 dbSNP
rs1237272150 262 dbSNP
rs372248767 263 dbSNP
rs985778758 271 dbSNP
rs756845746 275 dbSNP
rs911171788 276 dbSNP
rs1380449076 277 dbSNP
rs1242266957 279 dbSNP
rs1016064970 282 dbSNP
rs766815048 283 dbSNP
rs9234 293 dbSNP
rs1223367547 294 dbSNP
rs1283391642 302 dbSNP
rs556494118 305 dbSNP
rs1444408422 317 dbSNP
rs868143076 322 dbSNP
rs1456732724 323 dbSNP
rs775359136 330 dbSNP
rs954412119 333 dbSNP
rs1161474072 346 dbSNP
rs1048481427 348 dbSNP
rs1242969187 360 dbSNP
rs1180544698 361 dbSNP
rs909834860 365 dbSNP
rs1181063501 376 dbSNP
rs181387516 378 dbSNP
rs545295930 379 dbSNP
rs1317200674 380 dbSNP
rs13238 382 dbSNP
rs1426801838 383 dbSNP
rs185459237 390 dbSNP
rs1041878135 391 dbSNP
rs7888 392 dbSNP
rs144729786 397 dbSNP
rs1032128783 398 dbSNP
rs1454500085 399 dbSNP
rs1335170247 408 dbSNP
rs1349556609 411 dbSNP
rs1163096113 422 dbSNP
rs1426890658 423 dbSNP
rs1386280318 424 dbSNP
rs957934315 425 dbSNP
rs530123447 427 dbSNP
rs1347362392 436 dbSNP
rs1018128500 437 dbSNP
rs1224391905 438 dbSNP
rs188312371 441 dbSNP
rs73014492 442 dbSNP
rs531487392 443 dbSNP
rs1251850774 445 dbSNP
rs375284007 449 dbSNP
rs1179008438 450 dbSNP
rs10259 451 dbSNP
rs984609524 455 dbSNP
rs1008528123 460 dbSNP
rs910004820 462 dbSNP
rs1375339816 468 dbSNP
rs937328207 469 dbSNP
rs1055829719 470 dbSNP
rs777705615 476 dbSNP
rs1266063665 478 dbSNP
rs1196765940 479 dbSNP
rs917266203 482 dbSNP
rs950244608 483 dbSNP
rs527310225 488 dbSNP
rs113632426 491 dbSNP
rs567217191 492 dbSNP
rs1311608796 496 dbSNP
rs535333849 504 dbSNP
rs1059767 511 dbSNP
rs1307772485 512 dbSNP
rs893579101 515 dbSNP
rs1399126176 519 dbSNP
rs11539272 522 dbSNP
rs745687341 528 dbSNP
rs1427974830 529 dbSNP
rs200780462 531 dbSNP
rs556173622 532 dbSNP
rs1481196060 533 dbSNP
rs941441400 534 dbSNP
rs1038451976 546 dbSNP
rs998019690 547 dbSNP
rs769523012 556 dbSNP
rs899000211 559 dbSNP
rs781505808 565 dbSNP
rs1343931545 571 dbSNP
rs1025556151 591 dbSNP
rs570167097 595 dbSNP
rs1205690228 596 dbSNP
rs1324402328 598 dbSNP
rs984001892 599 dbSNP
rs909940063 601 dbSNP
rs1337847539 605 dbSNP
rs1047561402 606 dbSNP
rs958796511 608 dbSNP
rs991577818 614 dbSNP
rs1404585337 618 dbSNP
rs1334095278 641 dbSNP
rs1470641569 644 dbSNP
rs1406210498 645 dbSNP
rs917214306 646 dbSNP
rs538840388 656 dbSNP
rs977659469 659 dbSNP
rs775410481 668 dbSNP
rs1291332202 679 dbSNP
rs1185382577 680 dbSNP
rs1461774935 684 dbSNP
rs924917419 689 dbSNP
rs1017250666 695 dbSNP
rs936149722 700 dbSNP
rs752859166 703 dbSNP
rs900192739 709 dbSNP
rs1353192866 710 dbSNP
rs1261650909 712 dbSNP
rs376415760 718 dbSNP
rs1266313944 719 dbSNP
rs1381067771 725 dbSNP
rs1317725735 732 dbSNP
rs1382812771 733 dbSNP
rs148532968 735 dbSNP
rs942431459 736 dbSNP
rs1386732607 745 dbSNP
rs180700590 753 dbSNP
rs1460362768 754 dbSNP
rs900844373 763 dbSNP
rs1164931525 767 dbSNP
rs554682024 768 dbSNP
rs1035617545 780 dbSNP
rs1025505340 788 dbSNP
rs537176285 790 dbSNP
rs1262637165 793 dbSNP
rs1302682724 794 dbSNP
rs1005902686 795 dbSNP
rs991508201 809 dbSNP
rs1357655573 812 dbSNP
rs916578275 817 dbSNP
rs941397128 821 dbSNP
rs1016731969 824 dbSNP
rs958788010 829 dbSNP
rs974046772 833 dbSNP
rs1428097847 838 dbSNP
rs1327701864 844 dbSNP
rs1318498029 846 dbSNP
rs1403970812 851 dbSNP
rs1363476006 856 dbSNP
rs991566480 871 dbSNP
rs1425187823 874 dbSNP
rs1418779005 875 dbSNP
rs918636413 879 dbSNP
rs930073923 882 dbSNP
rs1024428338 886 dbSNP
rs761564042 895 dbSNP
rs971373588 896 dbSNP
rs1296676694 897 dbSNP
rs76045424 898 dbSNP
rs924623506 900 dbSNP
rs890308239 912 dbSNP
rs750040338 921 dbSNP
rs936237341 922 dbSNP
rs1286465561 923 dbSNP
rs1271439255 929 dbSNP
rs1360868232 933 dbSNP
rs543555762 936 dbSNP
rs910682448 937 dbSNP
rs1039394349 953 dbSNP
rs943580029 959 dbSNP
rs1343298675 961 dbSNP
rs563793988 964 dbSNP
rs1405280853 965 dbSNP
rs71338626 968 dbSNP
rs1326693871 973 dbSNP
rs10403469 974 dbSNP
rs1205382044 975 dbSNP
rs1046705253 976 dbSNP
rs1175876055 977 dbSNP
rs1260692515 978 dbSNP
rs1479559331 979 dbSNP
rs113607938 985 dbSNP
rs999300395 990 dbSNP
rs1469908765 993 dbSNP
rs1005427781 1006 dbSNP
rs1017302585 1011 dbSNP
rs1035183144 1016 dbSNP
rs1438972208 1020 dbSNP
rs1258112829 1023 dbSNP
rs1162964010 1028 dbSNP
rs11666036 1031 dbSNP
rs991085457 1032 dbSNP
rs1012783278 1042 dbSNP
rs1024376290 1043 dbSNP
rs1372266613 1052 dbSNP
rs527597771 1059 dbSNP
rs962940138 1065 dbSNP
rs1384608999 1069 dbSNP
rs971448546 1075 dbSNP
rs1339164111 1076 dbSNP
rs1336132396 1083 dbSNP
rs977515246 1085 dbSNP
rs1187833017 1095 dbSNP
rs547640103 1103 dbSNP
rs879410257 1111 dbSNP
rs1312225040 1118 dbSNP
rs974015370 1125 dbSNP
rs1355250887 1130 dbSNP
rs1031637076 1131 dbSNP
rs567151965 1134 dbSNP
rs529649260 1135 dbSNP
rs71338627 1136 dbSNP
rs541132048 1137 dbSNP
rs538876720 1139 dbSNP
rs1243554130 1142 dbSNP
rs910830162 1145 dbSNP
rs1281265393 1146 dbSNP
rs944575143 1148 dbSNP
rs552339273 1153 dbSNP
rs777952752 1157 dbSNP
rs751624486 1158 dbSNP
rs866782311 1162 dbSNP
rs923462020 1167 dbSNP
rs900391113 1172 dbSNP
rs777136235 1174 dbSNP
rs1365190716 1175 dbSNP
rs1450359042 1183 dbSNP
rs1385069489 1195 dbSNP
rs1181681643 1196 dbSNP
rs572053740 1205 dbSNP
rs1047252795 1206 dbSNP
rs1161582491 1210 dbSNP
rs1043396211 1214 dbSNP
rs1160008093 1220 dbSNP
rs902210356 1224 dbSNP
rs565901529 1226 dbSNP
rs540915845 1229 dbSNP
rs941055087 1230 dbSNP
rs896240403 1246 dbSNP
rs1181977300 1252 dbSNP
rs1012795518 1257 dbSNP
rs1023816750 1260 dbSNP
rs374548804 1261 dbSNP
rs1218389415 1263 dbSNP
rs1290840038 1264 dbSNP
rs1243681887 1270 dbSNP
rs1361559267 1281 dbSNP
rs555199157 1284 dbSNP
rs1452457945 1285 dbSNP
rs1038274947 1286 dbSNP
rs1359995461 1286 dbSNP
rs894419732 1288 dbSNP
rs1335307083 1292 dbSNP
rs868567587 1303 dbSNP
rs1376252632 1307 dbSNP
rs1025585534 1312 dbSNP
rs151191725 1312 dbSNP
rs962908935 1312 dbSNP
rs368146103 1317 dbSNP
rs951415214 1323 dbSNP
rs1170382038 1326 dbSNP
rs1045560246 1335 dbSNP
rs1416774560 1347 dbSNP
rs1427364830 1347 dbSNP
rs986899392 1347 dbSNP
rs912606263 1348 dbSNP
rs769644653 1355 dbSNP
rs907042268 1365 dbSNP
rs998912430 1374 dbSNP
rs1265919365 1375 dbSNP
rs946603671 1376 dbSNP
rs1225001069 1379 dbSNP
rs1043698294 1381 dbSNP
rs779812183 1382 dbSNP
rs957385746 1392 dbSNP
rs1281748381 1399 dbSNP
rs1239930185 1404 dbSNP
rs1480940959 1405 dbSNP
rs1012020950 1406 dbSNP
rs1460927427 1409 dbSNP
rs1177826705 1415 dbSNP
rs907571069 1421 dbSNP
rs1172246290 1423 dbSNP
rs960331581 1425 dbSNP
rs1056140971 1426 dbSNP
rs896195200 1432 dbSNP
rs1178853669 1433 dbSNP
rs537449503 1443 dbSNP
rs1267808738 1457 dbSNP
rs1012015675 1458 dbSNP
rs1479654609 1459 dbSNP
rs992092854 1465 dbSNP
rs1253118787 1468 dbSNP
rs1017839423 1471 dbSNP
rs1428076146 1479 dbSNP
rs59605281 1479 dbSNP
rs796505784 1479 dbSNP
rs1174779827 1481 dbSNP
rs1356768314 1495 dbSNP
rs1462966761 1507 dbSNP
rs1297069026 1508 dbSNP
rs1370546570 1511 dbSNP
rs1406332084 1513 dbSNP
rs1465657429 1556 dbSNP
rs2004443 1562 dbSNP
rs577399520 1563 dbSNP
rs1467313134 1568 dbSNP
rs1025889817 1569 dbSNP
rs1274913444 1570 dbSNP
rs951632237 1581 dbSNP
rs1252516738 1588 dbSNP
rs1179208545 1589 dbSNP
rs923409524 1590 dbSNP
rs1008618909 1597 dbSNP
rs1307953122 1599 dbSNP
rs1261350953 1607 dbSNP
rs1205789647 1618 dbSNP
rs1019632957 1619 dbSNP
rs950923256 1620 dbSNP
rs113575926 1621 dbSNP
rs908316144 1622 dbSNP
rs778501406 1625 dbSNP
rs1452569497 1626 dbSNP
rs1205807869 1640 dbSNP
rs565095572 1643 dbSNP
rs1381390134 1658 dbSNP
rs759772922 1660 dbSNP
rs1397382846 1665 dbSNP
rs1038419342 1666 dbSNP
rs1197655565 1667 dbSNP
rs1422135792 1668 dbSNP
rs572221014 1669 dbSNP
rs1381943975 1676 dbSNP
rs543171765 1677 dbSNP
rs975554987 1681 dbSNP
rs1443994657 1684 dbSNP
rs921755328 1685 dbSNP
rs1170377329 1687 dbSNP
rs386807406 1687 dbSNP
rs145531168 1688 dbSNP
rs146424375 1689 dbSNP
rs1261251596 1694 dbSNP
rs2363962 1697 dbSNP
rs1353221745 1712 dbSNP
rs907032570 1719 dbSNP
rs1245882336 1720 dbSNP
rs1357981509 1725 dbSNP
rs1402739536 1728 dbSNP
rs1056509672 1730 dbSNP
rs1340579405 1732 dbSNP
rs544461844 1734 dbSNP
rs1317114955 1741 dbSNP
rs917614031 1743 dbSNP
rs947780997 1745 dbSNP
rs1053197227 1750 dbSNP
rs893235055 1754 dbSNP
rs931440631 1758 dbSNP
rs1383251493 1766 dbSNP
rs1011681964 1773 dbSNP
rs1362403392 1775 dbSNP
rs1047234967 1778 dbSNP
rs887338333 1781 dbSNP
rs1008505493 1782 dbSNP
rs1191292774 1786 dbSNP
rs1489433888 1788 dbSNP
rs1017531502 1794 dbSNP
rs1222274077 1795 dbSNP
rs1489967553 1811 dbSNP
rs964692104 1821 dbSNP
rs997718846 1822 dbSNP
rs899865509 1824 dbSNP
rs563079507 1834 dbSNP
rs1224783363 1836 dbSNP
rs1278470810 1837 dbSNP
rs1404068278 1846 dbSNP
rs1021680366 1859 dbSNP
rs1224793989 1859 dbSNP
rs950871430 1867 dbSNP
rs1490237058 1884 dbSNP
rs112568036 1886 dbSNP
rs1244139752 1887 dbSNP
rs2363963 1891 dbSNP
rs565936688 1894 dbSNP
rs1424540720 1896 dbSNP
rs1186368729 1897 dbSNP
rs1030856094 1908 dbSNP
rs1248833948 1910 dbSNP
rs1447027947 1914 dbSNP
rs1437827057 1920 dbSNP
rs962746444 1929 dbSNP
rs1163611928 1933 dbSNP
rs1196158567 1938 dbSNP
rs535179443 1939 dbSNP
rs915540732 1941 dbSNP
rs1222539746 1942 dbSNP
rs1258229184 1942 dbSNP
rs1343404003 1946 dbSNP
rs1319891355 1954 dbSNP
rs992117121 1958 dbSNP
rs948408271 1964 dbSNP
rs981348275 1972 dbSNP
rs928566737 1983 dbSNP
rs917564083 1984 dbSNP
rs1401125525 1985 dbSNP
rs112571788 1989 dbSNP
rs1053341002 1990 dbSNP
rs892985506 1999 dbSNP
rs980405534 2005 dbSNP
rs1246667327 2007 dbSNP
rs1470052845 2017 dbSNP
rs947427632 2025 dbSNP
rs1481173233 2026 dbSNP
rs919641424 2035 dbSNP
rs1181058665 2045 dbSNP
rs1315740575 2047 dbSNP
rs931084199 2048 dbSNP
rs1039100101 2049 dbSNP
rs1202640607 2050 dbSNP
rs375584870 2051 dbSNP
rs1310121195 2053 dbSNP
rs548647595 2056 dbSNP
rs997498447 2057 dbSNP
rs1349726088 2069 dbSNP
rs1174447908 2074 dbSNP
rs1448918202 2076 dbSNP
rs1377726157 2077 dbSNP
rs371403566 2078 dbSNP
rs1450680448 2088 dbSNP
rs1361166613 2090 dbSNP
rs1177096172 2092 dbSNP
rs1400424482 2093 dbSNP
rs1406257674 2099 dbSNP
rs528828552 2100 dbSNP
rs1168170591 2101 dbSNP
rs1238224307 2104 dbSNP
rs1030520448 2107 dbSNP
rs1482004096 2109 dbSNP
rs1238803029 2121 dbSNP
rs1210389539 2130 dbSNP
rs1446149864 2134 dbSNP
rs1283688167 2135 dbSNP
rs886665629 2136 dbSNP
rs1354373983 2144 dbSNP
rs1005146279 2151 dbSNP
rs1246597761 2154 dbSNP
rs765749790 2159 dbSNP
rs1226627003 2160 dbSNP
rs1041339038 2164 dbSNP
rs1303586856 2169 dbSNP
rs1343801547 2170 dbSNP
rs1184754161 2173 dbSNP
rs900086365 2174 dbSNP
rs1241919523 2178 dbSNP
rs1442222789 2180 dbSNP
rs1162261318 2182 dbSNP
rs1159858025 2190 dbSNP
rs1415345380 2191 dbSNP
rs568714354 2197 dbSNP
rs1182068063 2198 dbSNP
rs963580870 2199 dbSNP
rs1474914273 2205 dbSNP
rs1260726019 2208 dbSNP
rs753083950 2209 dbSNP
rs1079098 2213 dbSNP
rs1021649636 2219 dbSNP
rs1290864010 2224 dbSNP
rs1219299630 2230 dbSNP
rs1323569300 2232 dbSNP
rs1313617505 2233 dbSNP
rs1022755568 2241 dbSNP
rs904583659 2244 dbSNP
rs998962206 2246 dbSNP
rs1280362926 2248 dbSNP
rs138557005 2251 dbSNP
rs969700003 2252 dbSNP
rs764533455 2255 dbSNP
rs577279810 2256 dbSNP
rs1351108829 2258 dbSNP
rs746734215 2258 dbSNP
rs568582853 2260 dbSNP
rs369347510 2264 dbSNP
rs969716280 2265 dbSNP
rs1477992919 2267 dbSNP
rs776445321 2269 dbSNP
rs988754546 2270 dbSNP
rs1445872340 2271 dbSNP
rs1266091175 2280 dbSNP
rs539940886 2281 dbSNP
rs1281395790 2285 dbSNP
rs1351610015 2291 dbSNP
rs914353243 2296 dbSNP
rs757291116 2312 dbSNP
rs1345256523 2313 dbSNP
rs781328186 2317 dbSNP
rs1388996727 2320 dbSNP
rs908701262 2320 dbSNP
rs1298125734 2322 dbSNP
rs944181352 2343 dbSNP
rs553460938 2347 dbSNP
rs1039079021 2348 dbSNP
rs149266115 2361 dbSNP
rs1263055151 2366 dbSNP
rs1434715082 2367 dbSNP
rs1043058626 2368 dbSNP
rs904552685 2371 dbSNP
rs1456453601 2380 dbSNP
rs1240164395 2381 dbSNP
rs933423864 2388 dbSNP
rs1232988001 2391 dbSNP
rs1469252760 2408 dbSNP
rs1051685816 2411 dbSNP
rs886447616 2417 dbSNP
rs1005506731 2420 dbSNP
rs1016555163 2421 dbSNP
rs1445291532 2422 dbSNP
rs1374012390 2424 dbSNP
rs1332839397 2427 dbSNP
rs899322195 2428 dbSNP
rs143771437 2429 dbSNP
rs1175492660 2430 dbSNP
rs1300754345 2435 dbSNP
rs1002107287 2436 dbSNP
rs1378005894 2437 dbSNP
rs1022704803 2440 dbSNP
rs1403784962 2443 dbSNP
rs1026603097 2448 dbSNP
rs952422477 2449 dbSNP
rs1411611555 2454 dbSNP
rs558356401 2466 dbSNP
rs1460944852 2478 dbSNP
rs969772336 2507 dbSNP
rs1202398897 2514 dbSNP
rs1002638363 2515 dbSNP
rs1035731586 2517 dbSNP
rs1336430382 2518 dbSNP
rs1238574977 2519 dbSNP
rs1441668153 2520 dbSNP
rs186265133 2521 dbSNP
rs1347687742 2530 dbSNP
rs989133580 2531 dbSNP
rs756305266 2534 dbSNP
rs1331729354 2537 dbSNP
rs1397472579 2543 dbSNP
rs1402633332 2544 dbSNP
rs138454383 2549 dbSNP
rs1297396724 2554 dbSNP
rs543319289 2556 dbSNP
rs1262938933 2559 dbSNP
rs1362326241 2565 dbSNP
rs1159210815 2577 dbSNP
rs562968166 2584 dbSNP
rs968935856 2598 dbSNP
rs1366811530 2600 dbSNP
rs1189874846 2617 dbSNP
rs1424656208 2620 dbSNP
rs974523779 2623 dbSNP
rs1262896217 2624 dbSNP
rs1214841710 2625 dbSNP
rs1198085883 2630 dbSNP
rs1273030049 2633 dbSNP
rs921780059 2645 dbSNP
rs976924350 2646 dbSNP
rs1355023982 2654 dbSNP
rs531936463 2655 dbSNP
rs1281985077 2657 dbSNP
rs1246489954 2663 dbSNP
rs1340747212 2663 dbSNP
rs1277202244 2672 dbSNP
rs921455632 2676 dbSNP
rs1270555977 2678 dbSNP
rs79802713 2685 dbSNP
rs1404762329 2692 dbSNP
rs1198360993 2703 dbSNP
rs1375749774 2704 dbSNP
rs1051799182 2706 dbSNP
rs907864715 2719 dbSNP
rs1423137609 2720 dbSNP
rs925939171 2721 dbSNP
rs1478976647 2726 dbSNP
rs934606094 2727 dbSNP
rs191865132 2732 dbSNP
rs940735884 2733 dbSNP
rs895868916 2734 dbSNP
rs528706740 2754 dbSNP
rs548747882 2766 dbSNP
rs1429177546 2771 dbSNP
rs899438242 2774 dbSNP
rs1356474243 2778 dbSNP
rs1306299096 2789 dbSNP
rs1216426377 2794 dbSNP
rs368935700 2795 dbSNP
rs1435646400 2796 dbSNP
rs1045229142 2802 dbSNP
rs1325482268 2805 dbSNP
rs1387361851 2812 dbSNP
rs1399664959 2816 dbSNP
rs1168783117 2820 dbSNP
rs1467445002 2834 dbSNP
rs1002076193 2835 dbSNP
rs568526188 2837 dbSNP
rs867037315 2844 dbSNP
rs1477256369 2845 dbSNP
rs906709662 2847 dbSNP
rs1003855009 2849 dbSNP
rs1200206997 2854 dbSNP
rs779863463 2856 dbSNP
rs1282968946 2857 dbSNP
rs1237096763 2861 dbSNP
rs73929060 2865 dbSNP
rs1035486726 2872 dbSNP
rs1273300444 2873 dbSNP
rs1218387693 2878 dbSNP
rs1342621520 2880 dbSNP
rs1276486301 2908 dbSNP
rs1233958998 2914 dbSNP
rs1376252098 2919 dbSNP
rs921434814 2927 dbSNP
rs1401237658 2933 dbSNP
rs1333788729 2934 dbSNP
rs1413055903 2935 dbSNP
rs955892786 2937 dbSNP
rs1427710963 2938 dbSNP
rs551246805 2941 dbSNP
rs1271283409 2942 dbSNP
rs978925734 2947 dbSNP
rs1009926846 2954 dbSNP
rs926156614 2961 dbSNP
rs1458738398 2963 dbSNP
rs1233030616 2975 dbSNP
rs1021726443 2976 dbSNP
rs754752167 2977 dbSNP
rs1293345851 2984 dbSNP
rs968575161 2986 dbSNP
rs1307015922 2988 dbSNP
rs1242354988 2995 dbSNP
rs1347241511 2997 dbSNP
rs1490400022 3000 dbSNP
rs974638217 3013 dbSNP
rs1221282448 3014 dbSNP
rs1264929803 3019 dbSNP
rs1283757416 3021 dbSNP
rs917269215 3024 dbSNP
rs35188036 3039 dbSNP
rs1361254622 3044 dbSNP
rs921728651 3049 dbSNP
rs1448502183 3051 dbSNP
rs1419504641 3054 dbSNP
rs950157026 3062 dbSNP
rs144096287 3070 dbSNP
rs987951534 3071 dbSNP
rs147314343 3072 dbSNP
rs553554779 3084 dbSNP
rs1471631371 3093 dbSNP
rs1238961565 3097 dbSNP
rs1211270163 3098 dbSNP
rs1487856104 3103 dbSNP
rs566952375 3104 dbSNP
rs1218720537 3105 dbSNP
rs550803620 3113 dbSNP
rs920605923 3118 dbSNP
rs570874846 3119 dbSNP
rs1381553418 3128 dbSNP
rs1004561740 3133 dbSNP
rs1399712458 3135 dbSNP
rs1045344798 3136 dbSNP
rs906699722 3142 dbSNP
rs1300573011 3144 dbSNP
rs1388932133 3153 dbSNP
rs1015246637 3158 dbSNP
rs1163524239 3174 dbSNP
rs1403114865 3177 dbSNP
rs539541364 3187 dbSNP
rs73511887 3200 dbSNP
rs1195746352 3201 dbSNP
rs1486176216 3208 dbSNP
rs1057264067 3212 dbSNP
rs953782300 3215 dbSNP
rs891519247 3216 dbSNP
rs1319450698 3231 dbSNP
rs1010412927 3237 dbSNP
rs1218317572 3241 dbSNP
rs1021254836 3242 dbSNP
rs1033195143 3242 dbSNP
rs1226881571 3244 dbSNP
rs117703583 3251 dbSNP
rs917257320 3252 dbSNP
rs543705493 3253 dbSNP
rs556796925 3254 dbSNP
rs1165178215 3259 dbSNP
rs950055648 3260 dbSNP
rs1421166061 3261 dbSNP
rs1428932173 3262 dbSNP
rs980134904 3262 dbSNP
rs927353436 3263 dbSNP
rs1352442522 3265 dbSNP
rs930747938 3266 dbSNP
rs1489499614 3268 dbSNP
rs879789188 3269 dbSNP
rs888307698 3278 dbSNP
rs1456650885 3282 dbSNP
rs1260266550 3288 dbSNP
rs1228559335 3290 dbSNP
rs987345346 3292 dbSNP
rs1037394737 3293 dbSNP
rs1015190100 3294 dbSNP
rs1372531790 3304 dbSNP
rs1326042816 3305 dbSNP
rs1445552856 3307 dbSNP
rs576471362 3309 dbSNP
rs1445312458 3310 dbSNP
rs1299530838 3311 dbSNP
rs962125003 3312 dbSNP
rs973905522 3317 dbSNP
rs920556180 3320 dbSNP
rs1028003811 3322 dbSNP
rs948076155 3323 dbSNP
rs1376917175 3324 dbSNP
rs1173866111 3330 dbSNP
rs1434882228 3338 dbSNP
rs1395746074 3342 dbSNP
rs772832697 3349 dbSNP
rs1366912281 3373 dbSNP
rs1455560866 3374 dbSNP
rs981014055 3379 dbSNP
rs759884002 3389 dbSNP
rs1483119559 3390 dbSNP
rs777660707 3390 dbSNP
rs1388370425 3394 dbSNP
rs1254693371 3400 dbSNP
rs956445775 3401 dbSNP
rs1309199855 3402 dbSNP
rs545371773 3404 dbSNP
rs1374034779 3405 dbSNP
rs559056461 3407 dbSNP
rs1391684661 3425 dbSNP
rs945775103 3431 dbSNP
rs59004821 3433 dbSNP
rs1024946321 3437 dbSNP
rs971686555 3437 dbSNP
rs980049159 3438 dbSNP
rs1365663981 3445 dbSNP
rs927322335 3447 dbSNP
rs528204649 3452 dbSNP
rs1310014367 3454 dbSNP
rs1254485409 3455 dbSNP
rs984873012 3456 dbSNP
rs1486221425 3467 dbSNP
rs1285861344 3474 dbSNP
rs904189376 3479 dbSNP
rs1215157115 3485 dbSNP
rs995827205 3486 dbSNP
rs1028848640 3487 dbSNP
rs890349901 3488 dbSNP
rs541531990 3489 dbSNP
rs111671163 3491 dbSNP
rs933939461 3497 dbSNP
rs530965305 3504 dbSNP
rs1297495572 3505 dbSNP
rs1049404311 3506 dbSNP
rs1205405833 3507 dbSNP
rs1387196828 3508 dbSNP
rs1159271998 3513 dbSNP
rs551334494 3514 dbSNP
rs1460853524 3517 dbSNP
rs571155818 3518 dbSNP
rs1167388946 3527 dbSNP
rs999945706 3527 dbSNP
rs1181306273 3533 dbSNP
rs973512051 3534 dbSNP
rs1263000481 3536 dbSNP
rs1254207884 3539 dbSNP
rs1421035038 3541 dbSNP
rs533395936 3543 dbSNP
rs1182813293 3544 dbSNP
rs891553809 3545 dbSNP
rs765539921 3555 dbSNP
rs1455967627 3556 dbSNP
rs1355041238 3561 dbSNP
rs1027776752 3564 dbSNP
rs969367282 3569 dbSNP
rs1234815629 3577 dbSNP
rs770741269 3581 dbSNP
rs1010792383 3592 dbSNP
rs1407446857 3593 dbSNP
rs547004017 3603 dbSNP
rs1318929386 3614 dbSNP
rs927961503 3616 dbSNP
rs1001771880 3620 dbSNP
rs1167363638 3620 dbSNP
rs1034304564 3624 dbSNP
rs952085103 3627 dbSNP
rs77331626 3629 dbSNP
rs1287322366 3630 dbSNP
rs1168915495 3632 dbSNP
rs1476609415 3633 dbSNP
rs939583207 3635 dbSNP
rs753166389 3636 dbSNP
rs566720478 3641 dbSNP
rs1198799380 3642 dbSNP
rs531235834 3643 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgagcgcgagugcgcAGGGGGUc 5'
                         ||||||| 
Target 5' -------------acUCCCCCAc 3'
 		1 - 10
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000359866.4 | 3UTR | ACUCCCCCACCCCCACUCCCUUUUCCACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
123 hsa-miR-4665-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT115350 IGF1R insulin like growth factor 1 receptor 2 8
MIRT144387 SF3B3 splicing factor 3b subunit 3 2 2
MIRT145421 ANKRD13B ankyrin repeat domain 13B 2 4
MIRT146684 MINK1 misshapen like kinase 1 2 2
MIRT178944 C11ORF57 chromosome 11 open reading frame 57 2 2
MIRT189772 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT238514 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT366308 GDI1 GDP dissociation inhibitor 1 2 4
MIRT375173 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT442321 WNT9B Wnt family member 9B 2 2
MIRT442581 HOXD9 homeobox D9 2 2
MIRT451170 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 2 2
MIRT451894 ILK integrin linked kinase 2 2
MIRT453620 SLC4A2 solute carrier family 4 member 2 2 2
MIRT454769 STOML3 stomatin like 3 2 2
MIRT455038 MEN1 menin 1 2 2
MIRT455151 SUV39H1 suppressor of variegation 3-9 homolog 1 2 2
MIRT456891 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457201 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT457373 CAMK2A calcium/calmodulin dependent protein kinase II alpha 2 2
MIRT459190 RCE1 Ras converting CAAX endopeptidase 1 2 2
MIRT462580 MYL12A myosin light chain 12A 2 2
MIRT464669 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT464753 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT464881 UBALD1 UBA like domain containing 1 2 2
MIRT465932 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466013 TMEM189 transmembrane protein 189 2 2
MIRT466905 STK38 serine/threonine kinase 38 2 10
MIRT468421 SETD1B SET domain containing 1B 2 2
MIRT468592 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT468853 RREB1 ras responsive element binding protein 1 2 2
MIRT468900 RPS6KA4 ribosomal protein S6 kinase A4 2 2
MIRT469189 RICTOR RPTOR independent companion of MTOR complex 2 2 2
MIRT469305 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT469771 RAB15 RAB15, member RAS oncogene family 2 2
MIRT469934 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470000 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT470585 POTEM POTE ankyrin domain family member M 2 2
MIRT470615 POTEG POTE ankyrin domain family member G 2 2
MIRT470932 PKM pyruvate kinase, muscle 2 2
MIRT472511 NACC1 nucleus accumbens associated 1 2 2
MIRT472843 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT473298 MEX3A mex-3 RNA binding family member A 2 2
MIRT473951 LRRC58 leucine rich repeat containing 58 2 2
MIRT474336 KMT2D lysine methyltransferase 2D 2 2
MIRT474399 KLHL28 kelch like family member 28 2 8
MIRT476487 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477597 EFNA3 ephrin A3 2 2
MIRT477857 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT479858 CCDC6 coiled-coil domain containing 6 2 2
MIRT480123 CALR calreticulin 2 2
MIRT480391 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480685 BRPF1 bromodomain and PHD finger containing 1 2 2
MIRT482326 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482513 ACTB actin beta 2 2
MIRT483244 CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 2 4
MIRT483282 SLC35C2 solute carrier family 35 member C2 2 4
MIRT483381 SPATA6 spermatogenesis associated 6 2 4
MIRT483416 RHOXF2B Rhox homeobox family member 2B 2 2
MIRT483468 STMN3 stathmin 3 2 4
MIRT484178 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484460 DDX6 DEAD-box helicase 6 2 2
MIRT484515 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484595 SIX3 SIX homeobox 3 2 6
MIRT484738 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT485248 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT485592 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT485912 PGPEP1 pyroglutamyl-peptidase I 2 4
MIRT485954 RTBDN retbindin 2 2
MIRT486597 METTL6 methyltransferase like 6 2 2
MIRT486807 NDOR1 NADPH dependent diflavin oxidoreductase 1 2 2
MIRT486972 STEAP3 STEAP3 metalloreductase 2 4
MIRT487364 C10orf54 V-set immunoregulatory receptor 2 2
MIRT488072 DLGAP3 DLG associated protein 3 2 4
MIRT488150 PRRC2B proline rich coiled-coil 2B 2 4
MIRT488454 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT489027 PRPF4B pre-mRNA processing factor 4B 2 2
MIRT489704 CALML3 calmodulin like 3 2 2
MIRT489757 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490015 PIEZO1 piezo type mechanosensitive ion channel component 1 2 2
MIRT490120 FN3K fructosamine 3 kinase 2 2
MIRT490187 PKNOX2 PBX/knotted 1 homeobox 2 2 2
MIRT490313 ANK1 ankyrin 1 2 4
MIRT490595 SLC47A1 solute carrier family 47 member 1 2 4
MIRT491133 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT493027 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT494199 CLIP2 CAP-Gly domain containing linker protein 2 2 2
MIRT495699 PADI1 peptidyl arginine deiminase 1 2 2
MIRT501149 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501413 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501638 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT512047 DIRAS2 DIRAS family GTPase 2 2 4
MIRT519877 ZFP30 ZFP30 zinc finger protein 2 4
MIRT522598 MAP7D1 MAP7 domain containing 1 2 4
MIRT524787 BAG5 BCL2 associated athanogene 5 2 2
MIRT539158 AR androgen receptor 2 2
MIRT555901 ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2 2
MIRT562543 CCDC71L coiled-coil domain containing 71 like 2 4
MIRT568791 VPS37D VPS37D, ESCRT-I subunit 2 2
MIRT569568 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT570000 COL1A2 collagen type I alpha 2 chain 2 2
MIRT570183 RAP1GAP2 RAP1 GTPase activating protein 2 2 2
MIRT572990 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT574618 LPCAT3 lysophosphatidylcholine acyltransferase 3 2 2
MIRT615354 CCNF cyclin F 2 2
MIRT616091 HOXB5 homeobox B5 2 2
MIRT617658 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT619107 CD40LG CD40 ligand 2 2
MIRT621198 ARPC1B actin related protein 2/3 complex subunit 1B 2 2
MIRT628839 FAM151B family with sequence similarity 151 member B 2 2
MIRT635552 LEPREL1 prolyl 3-hydroxylase 2 2 2
MIRT635703 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2 2
MIRT646646 FNBP1 formin binding protein 1 2 2
MIRT654905 POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2 2
MIRT655121 PHF7 PHD finger protein 7 2 2
MIRT659457 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 4
MIRT668952 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT684242 TBXA2R thromboxane A2 receptor 2 2
MIRT692701 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT694328 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT712137 TAOK1 TAO kinase 1 2 2
MIRT713672 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT715741 HSD11B1L hydroxysteroid 11-beta dehydrogenase 1 like 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4665 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4665 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4665 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4665 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4665-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4665-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4665-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4665-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4665-5p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4665-5p Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4665-5p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-4665-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4665-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4665-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4665-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4665-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4665-5p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4665-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4665-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

Error report submission