miRTarBase - #MIRT457335


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pre-miRNA Information
pre-miRNA hsa-mir-4524b   
Genomic Coordinates chr17: 69099542 - 69099656
Description Homo sapiens miR-4524b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4524b-3p
Sequence 66| GAGACAGGUUCAUGCUGCUA |85
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1263495678 1 dbSNP
rs1350790266 9 dbSNP
rs1322445998 14 dbSNP
Putative Targets

Gene Information
Gene Symbol REG4   
Synonyms GISP, REG-IV, RELP
Description regenerating family member 4
Transcript NM_001159352   
Other Transcripts NM_001159353 , NM_032044   
Expression
Putative miRNA Targets on REG4
3'UTR of REG4
(miRNA target sites are highlighted)		 
>REG4|NM_001159352|3'UTR
   1 AGCAAGAATCAAGATTCTGCTAACTCCTGCACAGCCCCGTCCTCTTCCTTTCTGCTAGCCTGGCTAAATCTGCTCATTAT
  81 TTCAGAGGGGAAACCTAGCAAACTAAGAGTGATAAGGGCCCTACTACACTGGCTTTTTTAGGCTTAGAGACAGAAACTTT
 161 AGCATTGGCCCAGTAGTGGCTTCTAGCTCTAAATGTTTGCCCCGCCATCCCTTTCCACAGTATCCTTCTTCCCTCCTCCC
 241 CTGTCTCTGGCTGTCTCGAGCAGTCTAGAAGAGTGCATCTCCAGCCTATGAAACAGCTGGGTCTTTGGCCATAAGAAGTA
 321 AAGATTTGAAGACAGAAGGAAGAAACTCAGGAGTAAGCTTCTAGACCCCTTCAGCTTCTACACCCTTCTGCCCTCTCTCC
 401 ATTGCCTGCACCCCACCCCAGCCACTCAACTCCTGCTTGTTTTTCCTTTGGCCATGGGAAGGTTTACCAGTAGAATCCTT
 481 GCTAGGTTGATGTGGGCCATACATTCCTTTAATAAACCATTGTGTACATAAGAGGTTGCTGTGTTCCAGTTCAGTAATGG
 561 TGAATGTGGAAAAGTGAAATAAGACCAAGAAATACACCCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aucgucguacuuGGACAGAg 5'
                      ||||||| 
Target 5' cttccctcctccCCTGTCTc 3'
 228 - 247 140.00 -12.90
2 
miRNA  3' aucGUCGUACUUGGACAGAg 5'
             | || | |:|||| || 
Target 5' tttCTGC-T-AGCCTGGCTa 3'
 49 - 66 115.00 -9.20
3 
miRNA  3' aucGUC-GU-ACUU------GGACAGAg 5'
             ||| || | ||      |:|||:| 
Target 5' cccCAGCCACTCAACTCCTGCTTGTTTt 3'
 416 - 443 111.00 -7.49
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN28795800 5 COSMIC
COSN26991948 13 COSMIC
COSN5353942 14 COSMIC
COSN30489429 17 COSMIC
COSN30131554 34 COSMIC
COSN30500327 34 COSMIC
COSN30508754 35 COSMIC
COSN30495361 37 COSMIC
COSN30516293 39 COSMIC
COSN30486288 41 COSMIC
COSN31495655 41 COSMIC
COSN30107682 54 COSMIC
COSN8635495 58 COSMIC
COSN30461950 83 COSMIC
COSN30452531 87 COSMIC
COSN30471291 90 COSMIC
COSN30124241 114 COSMIC
COSN30575965 134 COSMIC
COSN27089419 145 COSMIC
COSN30529372 184 COSMIC
COSN30101893 204 COSMIC
COSN30103008 232 COSMIC
COSN31555610 249 COSMIC
COSN30469230 258 COSMIC
COSN18725373 365 COSMIC
COSN26650573 366 COSMIC
COSN30449449 369 COSMIC
COSN30147868 397 COSMIC
COSN30534381 407 COSMIC
COSN26991949 408 COSMIC
COSN26991946 416 COSMIC
COSN31502344 427 COSMIC
COSN31545740 439 COSMIC
COSN30454190 445 COSMIC
COSN26991945 453 COSMIC
COSN25091167 456 COSMIC
COSN30130029 469 COSMIC
COSN32053618 473 COSMIC
COSN30455192 478 COSMIC
COSN30190359 480 COSMIC
COSN31495319 516 COSMIC
COSN26603302 517 COSMIC
COSN26636306 518 COSMIC
COSN31613107 526 COSMIC
COSN30520251 530 COSMIC
COSN30479933 532 COSMIC
COSN30155733 546 COSMIC
COSN13460796 569 COSMIC
COSN30107431 578 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1187827452 1 dbSNP
rs768085797 5 dbSNP
rs1474921901 10 dbSNP
rs140936954 14 dbSNP
rs1195735849 16 dbSNP
rs779238248 21 dbSNP
rs1331237723 24 dbSNP
rs757689676 26 dbSNP
rs1222068473 27 dbSNP
rs749580336 28 dbSNP
rs778204412 32 dbSNP
rs781508653 35 dbSNP
rs752907762 36 dbSNP
rs768524026 38 dbSNP
rs112954474 39 dbSNP
rs80287294 39 dbSNP
rs773951114 40 dbSNP
rs1360532878 41 dbSNP
rs587594305 43 dbSNP
rs1268146349 46 dbSNP
rs183767580 48 dbSNP
rs1213808300 57 dbSNP
rs775053318 59 dbSNP
rs587658207 62 dbSNP
rs1258417518 63 dbSNP
rs994070974 70 dbSNP
rs587773881 76 dbSNP
rs1318013969 84 dbSNP
rs1016770408 85 dbSNP
rs1164408147 98 dbSNP
rs1390784928 104 dbSNP
rs587705200 111 dbSNP
rs1344405277 118 dbSNP
rs1046245269 119 dbSNP
rs950148896 121 dbSNP
rs891992267 126 dbSNP
rs1053277717 129 dbSNP
rs755720774 131 dbSNP
rs1358405669 133 dbSNP
rs926200355 139 dbSNP
rs1200969804 140 dbSNP
rs887272813 147 dbSNP
rs1046830083 152 dbSNP
rs1488704229 158 dbSNP
rs1196191506 160 dbSNP
rs997875765 162 dbSNP
rs750054207 165 dbSNP
rs1260080165 168 dbSNP
rs1039391792 171 dbSNP
rs1300224508 183 dbSNP
rs974983841 187 dbSNP
rs1166076264 201 dbSNP
rs942334331 204 dbSNP
rs587650362 206 dbSNP
rs147308056 209 dbSNP
rs904448805 213 dbSNP
rs1161068620 218 dbSNP
rs587696315 222 dbSNP
rs1364474623 225 dbSNP
rs1042956289 235 dbSNP
rs79171404 236 dbSNP
rs1419929992 238 dbSNP
rs910862194 238 dbSNP
rs1354450644 240 dbSNP
rs1381390569 241 dbSNP
rs986985352 249 dbSNP
rs1342119347 250 dbSNP
rs955109513 252 dbSNP
rs945903623 253 dbSNP
rs112217556 254 dbSNP
rs1354588210 254 dbSNP
rs745444027 255 dbSNP
rs115301980 257 dbSNP
rs373373654 258 dbSNP
rs1383312921 261 dbSNP
rs1001429235 269 dbSNP
rs905886816 275 dbSNP
rs1024291366 286 dbSNP
rs928009646 293 dbSNP
rs1295921624 294 dbSNP
rs56822273 300 dbSNP
rs1439828333 310 dbSNP
rs969753952 323 dbSNP
rs1017178766 325 dbSNP
rs1422284248 326 dbSNP
rs1452608869 330 dbSNP
rs1303151406 333 dbSNP
rs1408095770 335 dbSNP
rs1370103256 338 dbSNP
rs1450351422 338 dbSNP
rs1314342673 339 dbSNP
rs1053159946 343 dbSNP
rs1242343570 346 dbSNP
rs984327828 346 dbSNP
rs7540526 351 dbSNP
rs699778 365 dbSNP
rs998735143 366 dbSNP
rs1460296393 369 dbSNP
rs1351760599 374 dbSNP
rs1163042695 375 dbSNP
rs1461174008 378 dbSNP
rs1424397367 379 dbSNP
rs41306173 384 dbSNP
rs1442123129 390 dbSNP
rs1018408907 393 dbSNP
rs1426621853 397 dbSNP
rs1178360745 399 dbSNP
rs369843810 401 dbSNP
rs761458299 402 dbSNP
rs1489338228 405 dbSNP
rs1176422650 407 dbSNP
rs1250972573 408 dbSNP
rs776224887 409 dbSNP
rs768175870 410 dbSNP
rs587613493 411 dbSNP
rs774958600 414 dbSNP
rs771334982 415 dbSNP
rs749717569 417 dbSNP
rs1295503505 424 dbSNP
rs778292591 425 dbSNP
rs375918455 430 dbSNP
rs587732153 431 dbSNP
rs904185859 436 dbSNP
rs1401339889 439 dbSNP
rs770323582 450 dbSNP
rs748406565 454 dbSNP
rs1043030032 455 dbSNP
rs1052972 456 dbSNP
rs1444311158 458 dbSNP
rs755129380 468 dbSNP
rs1415318372 469 dbSNP
rs751587388 471 dbSNP
rs1372781034 476 dbSNP
rs766397950 485 dbSNP
rs1393006816 486 dbSNP
rs750296601 487 dbSNP
rs765045879 489 dbSNP
rs1239630417 491 dbSNP
rs761546742 493 dbSNP
rs1480022189 494 dbSNP
rs972431275 496 dbSNP
rs776314663 497 dbSNP
rs1350730121 501 dbSNP
rs1301652768 502 dbSNP
rs1321703259 503 dbSNP
rs1234047909 504 dbSNP
rs180785881 506 dbSNP
rs760294717 516 dbSNP
rs1389948939 517 dbSNP
rs774846599 519 dbSNP
rs771550106 520 dbSNP
rs749760402 524 dbSNP
rs1373588219 525 dbSNP
rs1172724493 530 dbSNP
rs773808958 532 dbSNP
rs770334631 534 dbSNP
rs928073615 535 dbSNP
rs1418195451 540 dbSNP
rs909702960 562 dbSNP
rs1175373616 573 dbSNP
rs1424150464 574 dbSNP
rs766252406 589 dbSNP
rs1168287570 593 dbSNP
rs1353993826 594 dbSNP
rs948112085 595 dbSNP
rs909871427 597 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000354219.1 | 3UTR | CUUCUUCCCUCCUCCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
175 hsa-miR-4524b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT064889 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT075345 SF3B3 splicing factor 3b subunit 3 2 2
MIRT094174 PCGF3 polycomb group ring finger 3 2 6
MIRT100109 ABT1 activator of basal transcription 1 2 8
MIRT102242 HBP1 HMG-box transcription factor 1 2 2
MIRT124918 HCCS holocytochrome c synthase 2 2
MIRT140195 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT193891 HACD3 3-hydroxyacyl-CoA dehydratase 3 2 2
MIRT265634 LDHA lactate dehydrogenase A 2 2
MIRT303878 VAMP8 vesicle associated membrane protein 8 2 2
MIRT409756 CRTAP cartilage associated protein 2 4
MIRT441503 SPG20 spartin 2 6
MIRT446882 ZNF554 zinc finger protein 554 2 2
MIRT447093 COPRS coordinator of PRMT5 and differentiation stimulator 2 2
MIRT449987 AEN apoptosis enhancing nuclease 2 2
MIRT452116 IFITM1 interferon induced transmembrane protein 1 2 2
MIRT452654 ZNF33A zinc finger protein 33A 2 2
MIRT453886 IFRD1 interferon related developmental regulator 1 2 12
MIRT454143 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 2
MIRT454501 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT456633 ARMCX6 armadillo repeat containing, X-linked 6 2 2
MIRT457021 ACADSB acyl-CoA dehydrogenase, short/branched chain 2 2
MIRT457055 NEGR1 neuronal growth regulator 1 2 2
MIRT457335 REG4 regenerating family member 4 2 2
MIRT457421 CASC5 kinetochore scaffold 1 2 2
MIRT457940 LCE1A late cornified envelope 1A 2 2
MIRT458486 RMI1 RecQ mediated genome instability 1 2 10
MIRT458662 PAGR1 PAXIP1 associated glutamate rich protein 1 2 12
MIRT459784 IDH3A isocitrate dehydrogenase 3 (NAD(+)) alpha 2 2
MIRT459864 SVOP SV2 related protein 2 2
MIRT460575 FEM1A fem-1 homolog A 2 2
MIRT460987 STK17B serine/threonine kinase 17b 2 2
MIRT462315 TMEM109 transmembrane protein 109 2 2
MIRT464407 URM1 ubiquitin related modifier 1 2 2
MIRT465148 TSC22D2 TSC22 domain family member 2 2 2
MIRT466312 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466718 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT468258 SFXN4 sideroflexin 4 2 2
MIRT469140 RNF126 ring finger protein 126 2 2
MIRT471783 NUP153 nucleoporin 153 2 2
MIRT472506 NACC2 NACC family member 2 2 2
MIRT474588 KLF6 Kruppel like factor 6 2 2
MIRT475049 JOSD1 Josephin domain containing 1 2 2
MIRT476900 FBXO21 F-box protein 21 2 2
MIRT476972 FAM83G family with sequence similarity 83 member G 2 4
MIRT477433 EMP1 epithelial membrane protein 1 2 2
MIRT480334 C5orf51 chromosome 5 open reading frame 51 2 10
MIRT481179 AVL9 AVL9 cell migration associated 2 6
MIRT481693 AR androgen receptor 2 2
MIRT483280 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 4
MIRT485775 B4GALT5 beta-1,4-galactosyltransferase 5 2 2
MIRT487424 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT488002 RXRB retinoid X receptor beta 2 2
MIRT488259 DNLZ DNL-type zinc finger 2 4
MIRT490360 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT491593 USB1 U6 snRNA biogenesis phosphodiesterase 1 2 2
MIRT495269 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 4
MIRT495619 ZNF736 zinc finger protein 736 2 2
MIRT496167 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT496250 GJB2 gap junction protein beta 2 2 2
MIRT496915 RTKN rhotekin 2 2
MIRT498713 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 10
MIRT501106 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501831 NCOA3 nuclear receptor coactivator 3 2 2
MIRT507142 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT510991 PER1 period circadian clock 1 2 4
MIRT512283 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT513152 CSDC2 cold shock domain containing C2 2 2
MIRT513327 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 6
MIRT515090 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT516113 OARD1 O-acyl-ADP-ribose deacylase 1 2 8
MIRT516657 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT516892 PLEKHS1 pleckstrin homology domain containing S1 2 2
MIRT517966 ZMIZ2 zinc finger MIZ-type containing 2 2 4
MIRT519492 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT519799 ZNF226 zinc finger protein 226 2 2
MIRT524309 CTC1 CST telomere replication complex component 1 2 8
MIRT524425 CNKSR3 CNKSR family member 3 2 2
MIRT525927 KIAA0391 KIAA0391 2 2
MIRT528022 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT528227 METTL8 methyltransferase like 8 2 2
MIRT528686 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT528774 CD1D CD1d molecule 2 2
MIRT529935 P2RX7 purinergic receptor P2X 7 2 2
MIRT530642 PPIC peptidylprolyl isomerase C 2 4
MIRT530683 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT531922 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT532181 SEC14L5 SEC14 like lipid binding 5 2 4
MIRT534996 PRR11 proline rich 11 2 6
MIRT535452 PDCL phosducin like 2 4
MIRT544682 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT553757 TARBP2 TARBP2, RISC loading complex RNA binding subunit 2 4
MIRT560724 ZNF749 zinc finger protein 749 2 2
MIRT561518 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT561578 SLC30A1 solute carrier family 30 member 1 2 2
MIRT562483 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT565039 VAV2 vav guanine nucleotide exchange factor 2 2 2
MIRT565348 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT567104 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT568879 LY6H lymphocyte antigen 6 family member H 2 2
MIRT569141 NAP1L4 nucleosome assembly protein 1 like 4 2 2
MIRT569199 LRRC3C leucine rich repeat containing 3C 2 2
MIRT573559 TMEM120B transmembrane protein 120B 2 2
MIRT575931 Mrrf mitochondrial ribosome recycling factor 2 6
MIRT607035 MRRF mitochondrial ribosome recycling factor 2 9
MIRT607194 SPRY4 sprouty RTK signaling antagonist 4 2 2
MIRT609682 TMEM213 transmembrane protein 213 2 2
MIRT611227 ZNF274 zinc finger protein 274 2 2
MIRT611370 PLXDC1 plexin domain containing 1 2 4
MIRT611640 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT613011 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT613532 GTSE1 G2 and S-phase expressed 1 2 2
MIRT614459 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT616492 CD300E CD300e molecule 2 2
MIRT617288 GTF2H3 general transcription factor IIH subunit 3 2 2
MIRT618356 CDKL1 cyclin dependent kinase like 1 2 2
MIRT619529 ZNF74 zinc finger protein 74 2 2
MIRT619990 ZSCAN22 zinc finger and SCAN domain containing 22 2 2
MIRT621286 ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 2 2
MIRT621482 GPKOW G-patch domain and KOW motifs 2 2
MIRT625456 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT626757 NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 2 2
MIRT629138 CTCFL CCCTC-binding factor like 2 2
MIRT630092 DCAF10 DDB1 and CUL4 associated factor 10 2 2
MIRT633501 RNF14 ring finger protein 14 2 2
MIRT633604 APCDD1 APC down-regulated 1 2 2
MIRT633772 F2 coagulation factor II, thrombin 2 2
MIRT635605 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT637422 EPB41L3 erythrocyte membrane protein band 4.1 like 3 2 2
MIRT637822 PLA2G7 phospholipase A2 group VII 2 2
MIRT637978 RRP36 ribosomal RNA processing 36 2 2
MIRT638385 RABL3 RAB, member of RAS oncogene family like 3 2 2
MIRT638547 KIAA1549 KIAA1549 2 2
MIRT642019 NCKIPSD NCK interacting protein with SH3 domain 2 2
MIRT643342 MICA MHC class I polypeptide-related sequence A 2 2
MIRT644281 LRRC57 leucine rich repeat containing 57 2 2
MIRT646818 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT646839 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT646976 CYP2W1 cytochrome P450 family 2 subfamily W member 1 2 2
MIRT647735 CXCR2 C-X-C motif chemokine receptor 2 2 2
MIRT648598 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT649843 LIPG lipase G, endothelial type 2 2
MIRT650031 VHL von Hippel-Lindau tumor suppressor 2 2
MIRT652082 TSPAN14 tetraspanin 14 2 2
MIRT652103 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT652902 SYNPO2L synaptopodin 2 like 2 2
MIRT653549 SLC38A7 solute carrier family 38 member 7 2 2
MIRT653981 SEMA6B semaphorin 6B 2 2
MIRT654287 RCAN1 regulator of calcineurin 1 2 2
MIRT658372 FAM63B MINDY lysine 48 deubiquitinase 2 2 2
MIRT660321 BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2 2
MIRT663063 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT663269 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 2 2
MIRT664076 ZNF417 zinc finger protein 417 2 2
MIRT664193 MYOZ2 myozenin 2 2 2
MIRT664512 POLR3K RNA polymerase III subunit K 2 2
MIRT667025 PDF peptide deformylase, mitochondrial 2 2
MIRT669621 ACSL6 acyl-CoA synthetase long chain family member 6 2 2
MIRT670530 MLLT6 MLLT6, PHD finger containing 2 2
MIRT673050 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT683339 ZNF581 zinc finger protein 581 2 2
MIRT689264 WDR83OS WD repeat domain 83 opposite strand 2 2
MIRT690902 TOP2A DNA topoisomerase II alpha 2 2
MIRT699196 SLX4IP SLX4 interacting protein 2 2
MIRT702223 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT707053 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT707080 MED29 mediator complex subunit 29 2 2
MIRT712347 NLN neurolysin 2 2
MIRT714715 KIT KIT proto-oncogene receptor tyrosine kinase 2 2
MIRT715963 CES4A carboxylesterase 4A 2 2
MIRT718224 DEFB105B defensin beta 105B 2 2
MIRT718244 DEFB105A defensin beta 105A 2 2
MIRT721960 GCK glucokinase 2 2
MIRT723098 SERINC3 serine incorporator 3 2 2
MIRT725207 PTPRT protein tyrosine phosphatase, receptor type T 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4524b Tripterygium wilfordii Hook F resistant tissue
hsa-miR-4524b-3p Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)

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