miRTarBase - #MIRT457603


—
pre-miRNA Information
pre-miRNA hsa-mir-4481   
Genomic Coordinates chr10: 12653138 - 12653197
Description Homo sapiens miR-4481 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4481
Sequence 1| GGAGUGGGCUGGUGGUU |17
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1299710636 5 dbSNP
rs1433739601 12 dbSNP
rs1266754238 14 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol IDS   
Synonyms MPS2, SIDS
Description iduronate 2-sulfatase
Transcript NM_000202   
Other Transcripts NM_001166550 , NM_006123   
Expression
Putative miRNA Targets on IDS
3'UTR of IDS
(miRNA target sites are highlighted)		 
>IDS|NM_000202|3'UTR
   1 GTTTTGCCAACCATGGATGGCAAATGTGATGTGCTCCCTTCCAGCTGGTGAGAGGAGGAGTTAGAGCTGGTCGTTTTGTG
  81 ATTACCCATAATATTGGAAGCAGCCTGAGGGCTAGTTAATCCAAACATGCATCAACAATTTGGCCTGAGAATATGTAACA
 161 GCCAAACCTTTTCGTTTAGTCTTTATTAAAATTTATAATTGGTAATTGGACCAGTTTTTTTTTTAATTTCCCTCTTTTTA
 241 AAACAGTTACGGCTTATTTACTGAATAAATACAAAGCAAACAAACTCAAGTTATGTCATACCTTTGGATACGAAGACCAT
 321 ACATAATAACCAAACATAACATTATACACAAAGAATACTTTCATTATTTGTGGAATTTAGTGCATTTCAAAAAGTAATCA
 401 TATATCAAACTAGGCACCACACTAAGTTCCTGATTATTTTGTTTATAATTTAATAATATATCTTATGAGCCCTATATATT
 481 CAAAATATTATGTTAACATGTAATCCATGTTTCTTTTTCAAATCTAAAGTTAAAAAAAAATAGCAGAAGCCAGTGTCTTA
 561 AAGTCTATCTTTTGTTTCTAAGACCATGGGATTTCATAATCTCAAGATAAAATATGTATGAAGTAATTAATGTAGAATTT
 641 TTACACCAAATAATAAATAATGCTTAATAAACTAGAGATATGAGATGTGTAGGAAATTTGGTTAAACTTTTTTCAGATAC
 721 TTTCTGGCCCAAATAATAATTTGTTAGCAAATAATATGACCCTTGAACTCAATGGCCATCTATTAAAAGACTGTTGTTCA
 801 CACTGGAAAACATTTAAAGATGTGACTATATCCATGGGTGGATTGAATCACTCAAAATATATTAGTATCCTTCTTTAGGG
 881 ATGGTTGGTTACAGACATGTATTTATTCAGGAGGCAGAAAATATTCCATTTTAATTGCTTATTAAAGAAAACATTAAATT
 961 CTAAATTATTTTGAGGACTGTGAAGACTTTTCATTAGTGTAATATTAGGTCATTGTCAATCTCCCAGAATGTAGTTCTAT
1041 ATTCTCTAAATATGAAAGTATCCAGAAAGGCCAGTGGTAGTAAAAAGCTTAGTGTATATAATCTCAAAAGGGATGGAATA
1121 TTTACAACTCATATTTATAACATGTTGAATCTTCTCAGTTATCAGTAGTCATCAGAAGTGTCAATAGCTTTCTAAATAAA
1201 TATTAAATATCTACTGTCCTGTAGTGAAGGAGTAATTTTTAGTAATTTTCTCTTTACAAAGTCTCCAGTGTTTCCAGGTA
1281 AATATTTGTGAAACAAAATACAGCAAACTACATTGTTACTTCAGTGTATTGTTGCCAAAAATGACAAGATATTATATTAA
1361 AATCAGTAAATTTTAGACAGATTTTAAAAATTAATTAGCCTACAATAGAGGTTATATGGTAACACGGTGATCTTCTAAGC
1441 AGTTAAGTGACTGACTGTTCTGGCAACAACGACTTCTCCGTGACTGAAGGGCCCTGTTCATTTCCTGATCCTGAAGCTCG
1521 TCTCTCTTTTGAGCCTCCGCTTGCTTTGGTCGATGGTTTCCCTCAGCTTTTTCTTTGCTGTTCTTCATCCTCGTTGTTGC
1601 TGTCATCATGTTCACTGTGGCTTTTACAATACAGCCTGTAAATTCCTTATGACATAGTTCAGTGCATTTGGCTTTATTGC
1681 CTGCTCCACAGTTCTTTACCTTTACTTGGCTTAGAGAAACTGTATCTTTGTTGCTTCATATAACCTTTCCCCAACCCCAC
1761 TAAGCTGGACATAACTTATTAGTGGTCCTCCCGTCACTTTATTTGTAGAAATCTCTCTTTCACATGAGCAGGGGTTCTTT
1841 CATGTGGTTTAGCTGACAGCAGAACTAGTGATTCTAGACATTTTGCATGGCCCTCATTCAGTGGCTCACAAACATGAGGG
1921 AGCATCAGAACTACTTGAGGGGCTTGTTAAAACCCAGTGCGTTAGAAGTCGGATGCGGTGGCTCACACCTGTAATCCCAG
2001 CACTTTGGGAGGCCCAGGCAGGCGGATCACTTGAGGTTAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTC
2081 TCTACTAAAAATACAAAAGTTAGCCGGGTGTGGTGGTGCATGCCTGTAATCCCAGCTTCTTGGGAGGCCAAGGCACAAGA
2161 ATCGCTTGAACCAGGAGACGGAGGTTTCAGTGAATGAAGATCGTGCCATTGTATTCCAGCCTCGGCAACACAGCAGGACT
2241 GTGATTTTCTTTGGAGACTCCTAGATTTTCTGTGGTTTTGAACTGAATTTGTTGGATGTTGGCAAGTGCCTCTTATGAGC
2321 TGTTTCTTTATCCTGCATTTGCCCCACAAAGACTTATCTGGAGGTGAGCAAAGTATGTTTGGTAGTGAGGTCACAAAGGC
2401 AATCAGCCCCTTCCTCCCCACTCCCATTGCCATCTTCTCAGTCCTTCTCCCTTTCTTTCCAAGTAGTTTACCCACCCCTC
2481 CTCTTTCCTCCCCTGTCCCTAAAATAATCCACGTGTCTTCCTAAAATCTCTCTTTGATCCTGTCCTTTGATAACACCGTC
2561 AGTGCCTACTACTGGGTCTAGACAGACCTCTGTTGAGCAGTCAGAGTCTTCCCTGACTCCACAATGCCCCTTTCCTTGGC
2641 TGACCAGTATGACTACTGGTCCCCACCTTTCCCTTGCCTATCCCTACCTCCCTCCTACTAGGTTGTCCCATCCCTCTCTT
2721 CACCCATTCATTCATGACCATTTTTCACTACCAAGCTCCCCCCCTCCCGAAGGAGGCTGAGGTTTTTGTGACTCTCTAGA
2801 CTCTATTGTGGGATGGAATGAACATTGCTAAAGAATCTTGTGTTCGCTTTACTTTAAAAAGGTATTTTTTTCCTAATTAT
2881 AAAACTGATGTGTCAGTTACGGAAAAATTAGAAATGCAGCACAAATACATGAATATTTTACCACAAAATTGCCATATAAT
2961 ATCTTGTCTTTTTTGGGGGTGTGAATTTTTTGCATTGTTCTGGTCATATTCTTTATCATGTAATTTATGTTCTTTTTTAC
3041 TAAGTATTATGTGTGGTTATTATAGATTTTCACAAAGATATATTGCTGGTAATATATTTTATTGTGTAGTCTTATAATTT
3121 ACTTAACCTTCTTTCAATTGTTAGAAATTTAGGCTATTTCCAGATTTTCAGTATTGTAAATAATGCTGTGATGACCAATT
3201 TTGTGAATAAAATGTTTTTATGTATTTCAGATTATTCCCTTAGGATAGTCTCTCAGTGCCAAGTTGTCAAAAACATCTCT
3281 ATTTTGCTTATCTTCCTGCTCTCTTGCTGCCTTAGGGGGTAGTAAACTGAAACATAAAGTAAACATGCATACAAATAAAA
3361 AACATAAAACAAAAATAAGCAACCTGATGGTAATAGGTGAAAGTGGTAACCTGTTTTAACTTTGAATTCTTGCCGGGCGC
3441 GGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACGAGGTCAGGAGTTCAAAACCAGCCTG
3521 GCCAAGATGGTGAAATCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAATCCCAGCTA
3601 CTTGGGAGGCTGAGGCAGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCA
3681 GCCTGGGTGACAGAGCGAGACTCCGTCTCAAATAAAAAACAACAAAAAACAAAAAAAACTTAAAATTCTTTGCTTGTTAG
3761 TGACCTTGATCATGGTTCTCTTTGTACGATAGTTGGGCATCTGTATTTCCACTTGTGTGAATTTGCCTTTAAATTTTGGT
3841 TATGGGTTTCACCTTTTAAAATAATCAAACATATTTATCTTTTCCTGTGTGATAGGTTTTTTTCTGTATCTTTTCCTGTT
3921 AAACACACAGACCCCTCCCCAATCTGGACATTGAATAAATATTCATTTTCCTTTGCATTGTTTGGGGTTTGGTTTTATGC
4001 TTACTGTGTCTCTCCACCCCATTATCAGAGTAATATATGCTCATTGCATAAAATCTGGAACATGTGAAAACTGGAGATGA
4081 AAAGAAGCCCAGCATTTGAGACATACCCACTGCTGACATTTGTATATTTCCTTTCATTCTTTTACCTGCCTAAAGACATA
4161 TATGCAGATATGGACATATTTAGCTTTACATACATGCAGACTACCACATATAATCTATATCTTGTTTTTTTGATCTAACA
4241 CAATGTTAGCTTGGTTTTTTATGTCATTGACAGTTCTTGATTAACAGCTGTAATGGCTGCACAGCCCTGCTTCATTAATT
4321 TTTTTTTTTGGACTGAAATGTATGTACCACGTTCCGCTTATCCATTCATCCACCAGTGACCACTTGGGTCATTTCTACCT
4401 TTTGGCCATTGCAATAATGTTGCTGTCAACAAGGATGTACAAATATCTGTTCGAGTCCCTGCTCTTAATTGTTTTGGGTA
4481 TACACCCAACCTACATTAATCTTTAATCACTTAAGATGTTGGGGTTTGTGCTGGGAGGTAACCAAGTGACTCTGGAGCAG
4561 CCTCACCCTAGCTACAGAGGGAAACTGACTCTTCCCTCTCTGCCCAATCTTTTGCCGCCTGTCAGGTTCCCAAGCTGTCC
4641 ATACCTTACTGTGTGAAGCGCTTTGGGTATAAACTCCCAAATAGAGGCTCAGCCCCTTTTCCTTTCCCAAGTCCATCCTG
4721 CAGGTTATAGCTCTTCAGAGGAATCTCTTGAATTCTGGCCTGGGATCTGGGATTAAAGTAGAACCCAGGGTGTCCCTTGG
4801 GGCCTTAGGCATAGCCCGTTGTGGTGGAACCTGCCATCAGCCCCACTGCACTCAGTGGTCCCCTGGTACTTCAGGACAGT
4881 TTCTCTCTTCTGCACATGAGAACTTCAAGCAGAGAGGACTGTCAGTTGTTGCCTTCACATCACCAATCGTTTGGCCATAA
4961 TGGCCAAGAGCCCTCACTGCTCTTGGGTCTTGCCTTTCCACATGTTACTGAAAGCTCCCGTTGGTGTCCCTGTCCACTAA
5041 CTCACCTGATGGGACAGATGCCACTTTCCTCTGAGTGTCTGATAAAACACAGTCTGTTGTGGGGAGCCCACGCTCAAGGG
5121 TTTTCTTTGGGATCAGAGTTTCCCGGCTATTACTCCATGCCCTGCCTGACATCACTGTCATGTATGGTGCTAATCACCAA
5201 AGGATGCCCTTGTTTGATTCTGGATTCTAGGTGATAGTCCTTATCCTCTGATGGGGGAAGAGTTTGGGTGGGAGAGAACA
5281 AACCGACAAGTTGGTTCCAGATGAGGTGGCTGGGAGCCAACCCTCAGGTACTTGGCTCTGAGTAATGTGACGGCCCAGGC
5361 AAGAGGGCTCCCACTGCCAATGAGGAACAAAAGCTCAAGGTCTAGTAGTGTATTCAGCACATGCTAGGAAACAAGAGTTG
5441 GGACGTGGACAAGGAGAGGAGCAAAGGCCAGGGGTTAACTGCTTTTGGTTTTTCCTCTATAAAAGTCAGGGACTATGATT
5521 TATATGGGTGAGAAGGTTTGGAGTAGGACTGAAGCTGCCATTTACAAACCCCTTGCCCTAATTTATTGTAGTTTTGGGTG
5601 TGTTTCTGAAAGAACCTTTTGCAGGTGATTTTTATTCAGTACTCATTAACTTACAGCTTTTATGAATTCACATCTTCTAC
5681 ACTATTGAAAAACATAAGTTTGTATTGTGTTAAGTGCAGCATGAGTTATTATATGAATAAATCACATTAAATTTGCAAAA
5761 AAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGGUGGUCGGGUGAGg 5'
            |: ||  ||||||| 
Target 5' ccCTTCCTCCCCACTCc 3'
 2408 - 2424 147.00 -20.50
2 
miRNA  3' uuGGUGGUC-GGGUGAgg 5'
            |||:||| ||||||  
Target 5' tgCCATCAGCCCCACTgc 3'
 4832 - 4849 143.00 -23.30
3 
miRNA  3' uuGGUGGUCGGGUGAgg 5'
            || | | ||||||  
Target 5' ttCCCCAACCCCACTaa 3'
 1747 - 1763 131.00 -14.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1198719 225 ClinVar
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs782355588 2 dbSNP
rs1219324212 6 dbSNP
rs375940553 7 dbSNP
rs1314769472 14 dbSNP
rs782432215 31 dbSNP
rs192118605 37 dbSNP
rs782584433 42 dbSNP
rs1268353577 54 dbSNP
rs1468372181 56 dbSNP
rs1212179763 61 dbSNP
rs1009125098 62 dbSNP
rs890729896 66 dbSNP
rs879986479 67 dbSNP
rs1026257602 69 dbSNP
rs1405801789 72 dbSNP
rs1421124264 73 dbSNP
rs1160259798 77 dbSNP
rs14950 80 dbSNP
rs782405572 87 dbSNP
rs782283629 90 dbSNP
rs782355935 92 dbSNP
rs782635393 95 dbSNP
rs993495179 101 dbSNP
rs1351573990 103 dbSNP
rs188552517 105 dbSNP
rs1297118996 114 dbSNP
rs185589028 160 dbSNP
rs1229691409 167 dbSNP
rs1288633571 174 dbSNP
rs1333680111 202 dbSNP
rs1231869575 203 dbSNP
rs1292421279 217 dbSNP
rs948825586 218 dbSNP
rs782573761 224 dbSNP
rs1231660968 225 dbSNP
rs1257101128 225 dbSNP
rs376528035 225 dbSNP
rs377325959 225 dbSNP
rs71753099 225 dbSNP
rs868956775 226 dbSNP
rs1057379856 233 dbSNP
rs1162532076 250 dbSNP
rs1415620782 251 dbSNP
rs1405723041 262 dbSNP
rs193133326 311 dbSNP
rs148929875 312 dbSNP
rs781831717 315 dbSNP
rs189108448 317 dbSNP
rs1412471804 322 dbSNP
rs1286339738 331 dbSNP
rs1357567096 343 dbSNP
rs1214348745 352 dbSNP
rs782113338 366 dbSNP
rs1344871876 393 dbSNP
rs1205992086 404 dbSNP
rs781871377 411 dbSNP
rs182115584 412 dbSNP
rs145734314 418 dbSNP
rs1190404017 424 dbSNP
rs1238265036 432 dbSNP
rs1473026600 441 dbSNP
rs964151949 443 dbSNP
rs1417324664 459 dbSNP
rs1017751280 494 dbSNP
rs781919857 509 dbSNP
rs1374265967 525 dbSNP
rs987626521 540 dbSNP
rs1335857834 541 dbSNP
rs1432315234 541 dbSNP
rs1340672539 543 dbSNP
rs1430486711 553 dbSNP
rs1268744597 566 dbSNP
rs954949025 577 dbSNP
rs1026566959 603 dbSNP
rs1229716038 604 dbSNP
rs191299577 610 dbSNP
rs782149968 623 dbSNP
rs1345899657 639 dbSNP
rs1202216861 645 dbSNP
rs1279666092 671 dbSNP
rs782027282 677 dbSNP
rs1214848562 680 dbSNP
rs1245896283 684 dbSNP
rs1451271853 693 dbSNP
rs1189207619 701 dbSNP
rs1394403488 704 dbSNP
rs899139465 715 dbSNP
rs1016693311 727 dbSNP
rs1173766464 729 dbSNP
rs1402504640 730 dbSNP
rs1399687474 732 dbSNP
rs1316695847 737 dbSNP
rs1391358804 741 dbSNP
rs1436269653 743 dbSNP
rs1303366687 744 dbSNP
rs782363819 753 dbSNP
rs1235541794 760 dbSNP
rs1012979928 765 dbSNP
rs1275471417 767 dbSNP
rs1350237582 772 dbSNP
rs1222221267 788 dbSNP
rs782789624 791 dbSNP
rs1466141974 793 dbSNP
rs1209093143 834 dbSNP
rs1252356505 863 dbSNP
rs1449752713 866 dbSNP
rs1200372269 867 dbSNP
rs1377637240 897 dbSNP
rs1056953729 899 dbSNP
rs1469169607 899 dbSNP
rs1156512118 912 dbSNP
rs782095920 926 dbSNP
rs782318449 928 dbSNP
rs1392958814 929 dbSNP
rs782205097 949 dbSNP
rs782672366 952 dbSNP
rs1335312699 953 dbSNP
rs1236970669 954 dbSNP
rs1290491146 967 dbSNP
rs947298235 978 dbSNP
rs1228806950 997 dbSNP
rs1272235130 1039 dbSNP
rs782561209 1044 dbSNP
rs1211623899 1052 dbSNP
rs1267966800 1071 dbSNP
rs781893982 1082 dbSNP
rs781855533 1093 dbSNP
rs1179358814 1094 dbSNP
rs4844025 1127 dbSNP
rs1472691764 1131 dbSNP
rs1164666034 1142 dbSNP
rs1367027710 1143 dbSNP
rs1459758425 1147 dbSNP
rs1164412363 1148 dbSNP
rs1396371533 1151 dbSNP
rs1389801517 1153 dbSNP
rs1309881787 1156 dbSNP
rs1351340369 1158 dbSNP
rs1414331287 1173 dbSNP
rs1338551726 1187 dbSNP
rs1246673731 1191 dbSNP
rs912331908 1202 dbSNP
rs1266011894 1208 dbSNP
rs1338612193 1210 dbSNP
rs1202449007 1226 dbSNP
rs987599328 1235 dbSNP
rs1483187699 1250 dbSNP
rs1186854541 1258 dbSNP
rs1253641576 1259 dbSNP
rs1425971719 1263 dbSNP
rs1188657365 1265 dbSNP
rs186870252 1269 dbSNP
rs919435433 1270 dbSNP
rs972262050 1296 dbSNP
rs963986072 1315 dbSNP
rs1016248615 1323 dbSNP
rs1434177121 1332 dbSNP
rs1301355922 1333 dbSNP
rs1381587517 1336 dbSNP
rs1397585659 1342 dbSNP
rs1313110818 1344 dbSNP
rs1013362614 1366 dbSNP
rs1226009483 1378 dbSNP
rs958809818 1381 dbSNP
rs1035737869 1394 dbSNP
rs182686429 1398 dbSNP
rs1342343145 1399 dbSNP
rs782128493 1402 dbSNP
rs1209492448 1416 dbSNP
rs781984043 1425 dbSNP
rs1484003271 1426 dbSNP
rs782687860 1430 dbSNP
rs1201423639 1432 dbSNP
rs1041589839 1457 dbSNP
rs1191122584 1458 dbSNP
rs1391289456 1460 dbSNP
rs1453917705 1461 dbSNP
rs1173981976 1468 dbSNP
rs1361147794 1470 dbSNP
rs1466684808 1471 dbSNP
rs1303226256 1476 dbSNP
rs1387709291 1479 dbSNP
rs1011479652 1500 dbSNP
rs3087810 1504 dbSNP
rs1432633462 1508 dbSNP
rs893070028 1519 dbSNP
rs1039362512 1520 dbSNP
rs942398067 1523 dbSNP
rs73640665 1532 dbSNP
rs782742133 1533 dbSNP
rs146600601 1538 dbSNP
rs1259777413 1542 dbSNP
rs919404278 1551 dbSNP
rs782811357 1552 dbSNP
rs1249211514 1560 dbSNP
rs1468396513 1592 dbSNP
rs963649981 1593 dbSNP
rs782110431 1605 dbSNP
rs1427288317 1608 dbSNP
rs1433832292 1634 dbSNP
rs1158740603 1636 dbSNP
rs144428481 1648 dbSNP
rs17252662 1656 dbSNP
rs6641186 1657 dbSNP
rs1389332661 1667 dbSNP
rs1064463 1678 dbSNP
rs782220362 1679 dbSNP
rs1369185322 1689 dbSNP
rs1035706554 1690 dbSNP
rs1386811824 1720 dbSNP
rs1287381278 1721 dbSNP
rs1002934620 1730 dbSNP
rs191834447 1736 dbSNP
rs782306875 1758 dbSNP
rs1334783130 1760 dbSNP
rs1220082260 1768 dbSNP
rs1248961489 1769 dbSNP
rs1488872356 1778 dbSNP
rs59508039 1783 dbSNP
rs1249921579 1786 dbSNP
rs1473674582 1788 dbSNP
rs893047950 1790 dbSNP
rs1039990769 1792 dbSNP
rs782407774 1793 dbSNP
rs1404543344 1800 dbSNP
rs1162640555 1813 dbSNP
rs1351521736 1819 dbSNP
rs1457987694 1820 dbSNP
rs1306829172 1823 dbSNP
rs890764487 1828 dbSNP
rs1050737544 1844 dbSNP
rs929710551 1848 dbSNP
rs896938741 1852 dbSNP
rs186890639 1887 dbSNP
rs1226935707 1903 dbSNP
rs781995832 1922 dbSNP
rs1292704187 1923 dbSNP
rs1322799538 1936 dbSNP
rs1203956113 1942 dbSNP
rs1272490345 1947 dbSNP
rs1484169745 1952 dbSNP
rs942231917 1960 dbSNP
rs147148694 1961 dbSNP
rs782217576 1971 dbSNP
rs1179850604 1972 dbSNP
rs143500137 1976 dbSNP
rs1405814381 1977 dbSNP
rs184001799 1991 dbSNP
rs1167429557 1995 dbSNP
rs782382293 2001 dbSNP
rs1431101728 2011 dbSNP
rs1308302645 2013 dbSNP
rs1446312767 2022 dbSNP
rs138033183 2023 dbSNP
rs147395729 2024 dbSNP
rs1020417824 2033 dbSNP
rs1296012704 2036 dbSNP
rs1344498258 2051 dbSNP
rs1205945385 2063 dbSNP
rs142809960 2075 dbSNP
rs1440845486 2078 dbSNP
rs781858361 2105 dbSNP
rs1207796016 2106 dbSNP
rs5936293 2110 dbSNP
rs782458654 2140 dbSNP
rs1187895610 2148 dbSNP
rs1388243683 2155 dbSNP
rs782467736 2163 dbSNP
rs1450854800 2164 dbSNP
rs1168605350 2167 dbSNP
rs1424032656 2179 dbSNP
rs1412358177 2180 dbSNP
rs1336578359 2188 dbSNP
rs782189646 2190 dbSNP
rs1434827134 2201 dbSNP
rs891067160 2202 dbSNP
rs781839654 2203 dbSNP
rs1229242292 2208 dbSNP
rs1274293380 2210 dbSNP
rs1029272363 2214 dbSNP
rs150166269 2223 dbSNP
rs1221203281 2224 dbSNP
rs1279562504 2240 dbSNP
rs1461654004 2241 dbSNP
rs1207863416 2243 dbSNP
rs1246128357 2250 dbSNP
rs896907620 2260 dbSNP
rs1193315235 2263 dbSNP
rs782147463 2265 dbSNP
rs1476740603 2283 dbSNP
rs782682910 2293 dbSNP
rs1425420628 2301 dbSNP
rs1457061367 2307 dbSNP
rs1157315239 2310 dbSNP
rs1391513432 2311 dbSNP
rs782032446 2316 dbSNP
rs1436402361 2357 dbSNP
rs373377758 2382 dbSNP
rs1323453835 2385 dbSNP
rs1329459759 2391 dbSNP
rs941132463 2398 dbSNP
rs191849217 2400 dbSNP
rs1328679228 2405 dbSNP
rs1227558929 2407 dbSNP
rs1265962132 2408 dbSNP
rs1331164245 2421 dbSNP
rs140905513 2430 dbSNP
rs1055990483 2432 dbSNP
rs1205692712 2443 dbSNP
rs937575415 2446 dbSNP
rs928904695 2448 dbSNP
rs1266544595 2470 dbSNP
rs782365780 2470 dbSNP
rs782521902 2471 dbSNP
rs1200306743 2474 dbSNP
rs1269164503 2484 dbSNP
rs782367233 2495 dbSNP
rs1180501683 2502 dbSNP
rs1414718034 2505 dbSNP
rs782189125 2512 dbSNP
rs1163256858 2558 dbSNP
rs913245590 2583 dbSNP
rs781866570 2623 dbSNP
rs1407166361 2624 dbSNP
rs1324209582 2655 dbSNP
rs957496876 2658 dbSNP
rs1350131744 2668 dbSNP
rs1408176435 2674 dbSNP
rs868943327 2678 dbSNP
rs782749726 2682 dbSNP
rs1352135978 2693 dbSNP
rs1239493564 2710 dbSNP
rs985341374 2739 dbSNP
rs1354091127 2746 dbSNP
rs955284685 2751 dbSNP
rs1029574125 2754 dbSNP
rs781936227 2755 dbSNP
rs781821129 2758 dbSNP
rs896796852 2759 dbSNP
rs782396733 2760 dbSNP
rs782692139 2762 dbSNP
rs782382712 2763 dbSNP
rs894922823 2764 dbSNP
rs1164318005 2765 dbSNP
rs1474035740 2765 dbSNP
rs1370080002 2766 dbSNP
rs782284115 2768 dbSNP
rs1310155602 2769 dbSNP
rs1371340116 2781 dbSNP
rs782618478 2788 dbSNP
rs782807952 2802 dbSNP
rs1056358640 2806 dbSNP
rs1338653788 2808 dbSNP
rs1001741605 2823 dbSNP
rs1315610543 2825 dbSNP
rs1340929481 2828 dbSNP
rs782212399 2845 dbSNP
rs1276351246 2846 dbSNP
rs782616121 2862 dbSNP
rs782014620 2863 dbSNP
rs782791720 2866 dbSNP
rs1200269344 2867 dbSNP
rs1254445441 2872 dbSNP
rs1444465423 2900 dbSNP
rs913203292 2901 dbSNP
rs1054485275 2909 dbSNP
rs1447750915 2916 dbSNP
rs1170497949 2919 dbSNP
rs1373891256 2935 dbSNP
rs8965 2945 dbSNP
rs1301295328 2964 dbSNP
rs1399850622 2967 dbSNP
rs1454373536 2971 dbSNP
rs1337376340 2979 dbSNP
rs1364297581 2985 dbSNP
rs1225550430 2986 dbSNP
rs1299125853 3001 dbSNP
rs11969 3003 dbSNP
rs1232136672 3010 dbSNP
rs1253849969 3018 dbSNP
rs1347657537 3037 dbSNP
rs985695544 3038 dbSNP
rs1204693826 3039 dbSNP
rs1247959308 3044 dbSNP
rs955169637 3045 dbSNP
rs922448357 3056 dbSNP
rs1190622603 3064 dbSNP
rs1262581174 3080 dbSNP
rs972600163 3089 dbSNP
rs782692634 3095 dbSNP
rs961300065 3114 dbSNP
rs1016997066 3117 dbSNP
rs1174307440 3131 dbSNP
rs1379576218 3157 dbSNP
rs1470842083 3163 dbSNP
rs1176802656 3167 dbSNP
rs1387856143 3172 dbSNP
rs1432748438 3173 dbSNP
rs1290532240 3180 dbSNP
rs1005251037 3181 dbSNP
rs1385725964 3185 dbSNP
rs1298808304 3194 dbSNP
rs186446456 3201 dbSNP
rs1033394220 3220 dbSNP
rs1327502870 3243 dbSNP
rs1003299475 3244 dbSNP
rs1261822996 3259 dbSNP
rs907343248 3271 dbSNP
rs1488231185 3295 dbSNP
rs781872764 3315 dbSNP
rs1269742190 3317 dbSNP
rs1480863437 3328 dbSNP
rs1199907455 3345 dbSNP
rs1010475871 3349 dbSNP
rs782729444 3368 dbSNP
rs1064467 3369 dbSNP
rs1054856974 3379 dbSNP
rs1161283724 3383 dbSNP
rs180697990 3387 dbSNP
rs1456977758 3397 dbSNP
rs911216508 3420 dbSNP
rs781799353 3429 dbSNP
rs782717636 3434 dbSNP
rs934095465 3435 dbSNP
rs1405233407 3438 dbSNP
rs922422108 3439 dbSNP
rs782192065 3440 dbSNP
rs1225820759 3441 dbSNP
rs35415606 3446 dbSNP
rs1308356648 3450 dbSNP
rs1321573457 3451 dbSNP
rs1219505334 3461 dbSNP
rs1267249401 3477 dbSNP
rs1490527332 3483 dbSNP
rs961268000 3484 dbSNP
rs1249881664 3486 dbSNP
rs1471518559 3495 dbSNP
rs1178661157 3501 dbSNP
rs909837485 3502 dbSNP
rs5936188 3511 dbSNP
rs1423127006 3512 dbSNP
rs1162576147 3526 dbSNP
rs1366944396 3528 dbSNP
rs1424741885 3531 dbSNP
rs1307089627 3535 dbSNP
rs201426579 3539 dbSNP
rs1368257558 3540 dbSNP
rs1444821737 3565 dbSNP
rs1280462364 3567 dbSNP
rs200754199 3568 dbSNP
rs1227153348 3570 dbSNP
rs1033774284 3572 dbSNP
rs1227743024 3575 dbSNP
rs5936292 3579 dbSNP
rs1484118562 3580 dbSNP
rs1206394526 3583 dbSNP
rs1233296492 3584 dbSNP
rs1482789187 3588 dbSNP
rs1180116115 3595 dbSNP
rs879996007 3604 dbSNP
rs970490966 3605 dbSNP
rs199533893 3608 dbSNP
rs201612383 3616 dbSNP
rs1444732765 3627 dbSNP
rs188442928 3635 dbSNP
rs1010444845 3641 dbSNP
rs892040967 3642 dbSNP
rs1033227946 3649 dbSNP
rs1358988989 3651 dbSNP
rs1000863873 3656 dbSNP
rs1339335690 3659 dbSNP
rs1384104009 3664 dbSNP
rs1434467918 3665 dbSNP
rs5936291 3666 dbSNP
rs782357554 3667 dbSNP
rs934064366 3669 dbSNP
rs201800308 3672 dbSNP
rs1215425281 3673 dbSNP
rs1278186775 3678 dbSNP
rs1141636 3696 dbSNP
rs1036822317 3704 dbSNP
rs939829586 3705 dbSNP
rs1461681878 3726 dbSNP
rs909713677 3738 dbSNP
rs1168206160 3739 dbSNP
rs1476090967 3739 dbSNP
rs1424009797 3746 dbSNP
rs1413130201 3748 dbSNP
rs1178943861 3778 dbSNP
rs1407508393 3780 dbSNP
rs1435078845 3787 dbSNP
rs984024424 3797 dbSNP
rs1319096596 3805 dbSNP
rs1328350787 3812 dbSNP
rs1431559828 3844 dbSNP
rs782671741 3853 dbSNP
rs1365675451 3857 dbSNP
rs3832 3862 dbSNP
rs1221496473 3869 dbSNP
rs1264720419 3874 dbSNP
rs1323961595 3878 dbSNP
rs782423181 3893 dbSNP
rs1282059506 3904 dbSNP
rs926261045 3910 dbSNP
rs1448285297 3928 dbSNP
rs1193197106 3935 dbSNP
rs981803455 3937 dbSNP
rs1479227606 3942 dbSNP
rs145834006 3950 dbSNP
rs1430482151 3953 dbSNP
rs1457045037 3960 dbSNP
rs1157668263 3962 dbSNP
rs149847110 3976 dbSNP
rs1401364233 4011 dbSNP
rs1322930878 4016 dbSNP
rs1348384473 4017 dbSNP
rs1407046508 4032 dbSNP
rs1284124275 4048 dbSNP
rs987893178 4054 dbSNP
rs1227539776 4077 dbSNP
rs1277714046 4084 dbSNP
rs1352661839 4087 dbSNP
rs185689277 4094 dbSNP
rs1288463242 4102 dbSNP
rs956198772 4114 dbSNP
rs1489622630 4130 dbSNP
rs1224345017 4148 dbSNP
rs1269145113 4162 dbSNP
rs781843057 4163 dbSNP
rs1472478383 4174 dbSNP
rs1180025410 4181 dbSNP
rs1366090446 4188 dbSNP
rs1033608895 4189 dbSNP
rs1163165824 4192 dbSNP
rs1411769543 4195 dbSNP
rs1426619633 4215 dbSNP
rs1304043443 4227 dbSNP
rs1370124366 4232 dbSNP
rs1408990659 4235 dbSNP
rs73617870 4253 dbSNP
rs1337484962 4254 dbSNP
rs1239734108 4263 dbSNP
rs1283525730 4267 dbSNP
rs1356724366 4271 dbSNP
rs782461618 4281 dbSNP
rs1028272474 4282 dbSNP
rs868974786 4290 dbSNP
rs1482501220 4302 dbSNP
rs1194464554 4308 dbSNP
rs1253168360 4310 dbSNP
rs998179289 4329 dbSNP
rs1438719089 4330 dbSNP
rs199727334 4330 dbSNP
rs201561946 4330 dbSNP
rs781884060 4330 dbSNP
rs1446535813 4342 dbSNP
rs1164215431 4347 dbSNP
rs901182560 4350 dbSNP
rs1460611611 4351 dbSNP
rs782429201 4355 dbSNP
rs1398454046 4356 dbSNP
rs1391749313 4358 dbSNP
rs782519154 4362 dbSNP
rs888260625 4363 dbSNP
rs1454147185 4390 dbSNP
rs782228331 4397 dbSNP
rs1340818895 4400 dbSNP
rs782807935 4400 dbSNP
rs1224838853 4418 dbSNP
rs1252695944 4419 dbSNP
rs1340571928 4429 dbSNP
rs937931679 4436 dbSNP
rs782613345 4438 dbSNP
rs981772337 4452 dbSNP
rs1463011609 4453 dbSNP
rs1184310089 4476 dbSNP
rs1247542072 4479 dbSNP
rs782104862 4486 dbSNP
rs12012551 4489 dbSNP
rs913578988 4499 dbSNP
rs1373805911 4504 dbSNP
rs987879925 4523 dbSNP
rs1462313679 4530 dbSNP
rs1175394030 4542 dbSNP
rs782721372 4546 dbSNP
rs1403848853 4549 dbSNP
rs782097614 4552 dbSNP
rs1470945094 4553 dbSNP
rs1337278254 4562 dbSNP
rs1363911305 4574 dbSNP
rs1380012847 4576 dbSNP
rs1297292683 4583 dbSNP
rs1326583841 4596 dbSNP
rs1233019224 4602 dbSNP
rs1261601953 4616 dbSNP
rs377465027 4617 dbSNP
rs1204902084 4619 dbSNP
rs1268040569 4620 dbSNP
rs1484943693 4622 dbSNP
rs782459389 4645 dbSNP
rs1262737796 4659 dbSNP
rs781792681 4665 dbSNP
rs979372916 4677 dbSNP
rs1197510358 4682 dbSNP
rs1426992634 4687 dbSNP
rs781916643 4695 dbSNP
rs1177136982 4701 dbSNP
rs954291597 4707 dbSNP
rs1451000502 4712 dbSNP
rs1028491942 4714 dbSNP
rs1404000926 4715 dbSNP
rs1280934981 4724 dbSNP
rs1347853429 4737 dbSNP
rs1224446980 4743 dbSNP
rs1288278873 4764 dbSNP
rs1315618429 4775 dbSNP
rs782323191 4778 dbSNP
rs1218066593 4789 dbSNP
rs1261438146 4792 dbSNP
rs1488181312 4796 dbSNP
rs1220625908 4801 dbSNP
rs35807183 4805 dbSNP
rs1271300704 4814 dbSNP
rs181363237 4817 dbSNP
rs1407207222 4824 dbSNP
rs1417178976 4830 dbSNP
rs965318821 4839 dbSNP
rs1363914782 4841 dbSNP
rs1015565358 4845 dbSNP
rs190167885 4883 dbSNP
rs1300921807 4889 dbSNP
rs1366982652 4894 dbSNP
rs888558348 4896 dbSNP
rs1297919063 4914 dbSNP
rs1371603549 4918 dbSNP
rs1226019263 4921 dbSNP
rs1308336693 4943 dbSNP
rs1048219194 4946 dbSNP
rs1002488876 4948 dbSNP
rs185029794 4949 dbSNP
rs1490563247 4955 dbSNP
rs1222982100 4956 dbSNP
rs1232134290 4990 dbSNP
rs1479516232 5010 dbSNP
rs1046312962 5015 dbSNP
rs782520784 5019 dbSNP
rs369925793 5020 dbSNP
rs1251136065 5037 dbSNP
rs1443488836 5041 dbSNP
rs782209527 5048 dbSNP
rs1386735029 5054 dbSNP
rs1424954672 5058 dbSNP
rs781978500 5092 dbSNP
rs200812994 5110 dbSNP
rs1444799429 5111 dbSNP
rs5936290 5112 dbSNP
rs1382601859 5119 dbSNP
rs1450581251 5124 dbSNP
rs1317188043 5144 dbSNP
rs1360224491 5145 dbSNP
rs1214243496 5153 dbSNP
rs782735488 5160 dbSNP
rs1271138269 5197 dbSNP
rs925063491 5210 dbSNP
rs73640664 5213 dbSNP
rs6641316 5218 dbSNP
rs1251851731 5223 dbSNP
rs1460781496 5235 dbSNP
rs921443877 5253 dbSNP
rs370590230 5262 dbSNP
rs976947899 5264 dbSNP
rs1444713074 5268 dbSNP
rs965621402 5284 dbSNP
rs1412001612 5287 dbSNP
rs879975709 5297 dbSNP
rs1171512836 5300 dbSNP
rs1015583956 5304 dbSNP
rs139517444 5330 dbSNP
rs781802397 5351 dbSNP
rs1339230690 5352 dbSNP
rs1383704198 5356 dbSNP
rs1430086034 5358 dbSNP
rs1268649761 5362 dbSNP
rs1364301502 5374 dbSNP
rs112421996 5380 dbSNP
rs1258522448 5390 dbSNP
rs1027446679 5395 dbSNP
rs1002301494 5404 dbSNP
rs904998679 5406 dbSNP
rs782243773 5414 dbSNP
rs1442512212 5415 dbSNP
rs1214372259 5440 dbSNP
rs1240031144 5444 dbSNP
rs1476160259 5445 dbSNP
rs190209465 5449 dbSNP
rs1429074898 5453 dbSNP
rs1479658384 5482 dbSNP
rs1179282080 5496 dbSNP
rs1407404552 5509 dbSNP
rs377294012 5525 dbSNP
rs1013491808 5530 dbSNP
rs1347017859 5537 dbSNP
rs1431801565 5540 dbSNP
rs1282884236 5542 dbSNP
rs1344707362 5550 dbSNP
rs1221405237 5554 dbSNP
rs1285123166 5565 dbSNP
rs1345577843 5573 dbSNP
rs1222724252 5598 dbSNP
rs1281580481 5604 dbSNP
rs1448186380 5604 dbSNP
rs782481349 5607 dbSNP
rs1267715118 5612 dbSNP
rs1201957284 5615 dbSNP
rs1378743814 5634 dbSNP
rs781834814 5639 dbSNP
rs1470118994 5653 dbSNP
rs1157308870 5655 dbSNP
rs1052103418 5657 dbSNP
rs782704645 5671 dbSNP
rs1302797027 5677 dbSNP
rs1363875416 5678 dbSNP
rs1402902361 5680 dbSNP
rs1304674831 5682 dbSNP
rs1331447529 5689 dbSNP
rs5936289 5697 dbSNP
rs1277697673 5698 dbSNP
rs5936288 5698 dbSNP
rs374452167 5699 dbSNP
rs782765815 5707 dbSNP
rs184747634 5719 dbSNP
rs921412884 5729 dbSNP
rs976915377 5744 dbSNP
rs1224226512 5747 dbSNP
rs1268546093 5756 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuGGUGGUCGGGUGAGg 5'
            |: ||  ||||||| 
Target 5' --CUUCCUCCCCACUCc 3'
 		1 - 15
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_000202 | 3UTR | GCCCCACAAAGACUUAUCUGGAGGUGAGCAAAGUAUGUUUGGUAGUGAGGUCACAAAGGCAAUCAGCCCCUUCCUCCCCACUCCCAUUGCCAUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001166550 | 3UTR | AGCCCCUUCCUCCCCACUCCCAUUGCCAUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_000202 | 3UTR | UUCCUCCCCACUCCCAUUGCCAUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_000202 | 3UTR | CCCUUCCUCCCCACUCCCAUUGCCAUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_000202 | 3UTR | CCUCCCCACUCCCAUUGCCAUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000340855.6 | 3UTR | CUUCCUCCCCACUCCCAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
84 hsa-miR-4481 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT100715 TJAP1 tight junction associated protein 1 2 2
MIRT183589 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT338033 DAZAP2 DAZ associated protein 2 2 4
MIRT395796 SPCS3 signal peptidase complex subunit 3 2 2
MIRT443947 LRIT3 leucine rich repeat, Ig-like and transmembrane domains 3 2 2
MIRT450580 HIST1H2BG histone cluster 1 H2B family member g 2 6
MIRT451617 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT452331 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT453279 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT455212 GNL1 G protein nucleolar 1 (putative) 2 2
MIRT455470 LYPLA2 lysophospholipase II 2 2
MIRT456503 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2 2
MIRT456687 LDB1 LIM domain binding 1 2 2
MIRT456915 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457603 IDS iduronate 2-sulfatase 2 2
MIRT457848 RNASEH2B ribonuclease H2 subunit B 2 4
MIRT458455 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT460179 UNK unkempt family zinc finger 2 6
MIRT461465 SLC19A3 solute carrier family 19 member 3 2 2
MIRT464739 UBE2Q1 ubiquitin conjugating enzyme E2 Q1 2 2
MIRT465279 TRIM28 tripartite motif containing 28 2 2
MIRT468450 SETD1B SET domain containing 1B 2 2
MIRT468620 SUMO1 small ubiquitin-like modifier 1 2 6
MIRT469152 RNF121 ring finger protein 121 2 2
MIRT470073 PTGES2 prostaglandin E synthase 2 2 2
MIRT470172 PSMD11 proteasome 26S subunit, non-ATPase 11 2 4
MIRT473156 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT474308 LAMC1 laminin subunit gamma 1 2 2
MIRT474782 KIAA0895L KIAA0895 like 2 2
MIRT476484 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477613 EFNA3 ephrin A3 2 2
MIRT479525 CDCA4 cell division cycle associated 4 2 2
MIRT479973 CARD10 caspase recruitment domain family member 10 2 2
MIRT480410 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480426 C17orf85 nuclear cap binding subunit 3 2 2
MIRT483573 SYT2 synaptotagmin 2 2 2
MIRT483664 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT484532 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484616 SIX3 SIX homeobox 3 2 6
MIRT485897 ZFP36 ZFP36 ring finger protein 2 2
MIRT486505 MYH11 myosin heavy chain 11 2 2
MIRT487505 GRK5 G protein-coupled receptor kinase 5 2 2
MIRT488852 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489464 MSC musculin 2 2
MIRT491170 LRP3 LDL receptor related protein 3 2 2
MIRT496627 TMEM67 transmembrane protein 67 2 2
MIRT497616 ANG angiogenin 2 2
MIRT497766 KIAA0895 KIAA0895 2 2
MIRT499680 MRE11A MRE11 homolog, double strand break repair nuclease 2 6
MIRT499774 SLC29A2 solute carrier family 29 member 2 2 2
MIRT501745 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT504995 ZNF652 zinc finger protein 652 2 2
MIRT511664 HIST1H3C histone cluster 1 H3 family member c 2 2
MIRT511690 HIST1H2BO histone cluster 1 H2B family member o 2 4
MIRT511703 HIST1H2BL histone cluster 1 H2B family member l 2 4
MIRT511734 HIST1H2BE histone cluster 1 H2B family member e 2 8
MIRT512858 TBC1D13 TBC1 domain family member 13 2 2
MIRT513444 EMP1 epithelial membrane protein 1 2 6
MIRT515681 TFPI tissue factor pathway inhibitor 2 2
MIRT523529 GLUL glutamate-ammonia ligase 2 2
MIRT525546 PHB2 prohibitin 2 2 4
MIRT526209 SNX24 sorting nexin 24 2 2
MIRT531554 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT533764 TMEM135 transmembrane protein 135 2 2
MIRT545582 SNRPA1 small nuclear ribonucleoprotein polypeptide A' 2 2
MIRT552434 ZNF460 zinc finger protein 460 2 2
MIRT561159 BCL2L12 BCL2 like 12 2 2
MIRT562345 EXOSC2 exosome component 2 2 2
MIRT570659 KDM6B lysine demethylase 6B 2 2
MIRT571076 TCHHL1 trichohyalin like 1 2 2
MIRT571330 TPCN2 two pore segment channel 2 2 2
MIRT571603 TOB2 transducer of ERBB2, 2 2 2
MIRT573013 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT609041 EP300 E1A binding protein p300 2 2
MIRT613398 DNAH17 dynein axonemal heavy chain 17 2 2
MIRT635589 TTC9C tetratricopeptide repeat domain 9C 2 2
MIRT661118 FPR1 formyl peptide receptor 1 2 2
MIRT690103 PNMA2 paraneoplastic Ma antigen 2 2 2
MIRT694972 PLAC8 placenta specific 8 2 2
MIRT695515 ALPI alkaline phosphatase, intestinal 2 2
MIRT695578 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT699570 SIT1 signaling threshold regulating transmembrane adaptor 1 2 2
MIRT701991 MIER3 MIER family member 3 2 2
MIRT725464 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4481 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-mir-4481 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-4481 Tamoxifen 2733525 NSC180973 approved resistant cell line (MCF7)
hsa-mir-4481 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4481 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4481 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4481 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4481 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4481 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

Error report submission